ライフサイエンスコーパス: exoenzyme S

1 yltransferase activity of the 53-kDa form of exoenzyme S.

2 as contributing to the catalytic activity of exoenzyme S.

3 med Exo53, which reacted to antisera against exoenzyme S.

4 eutralized the ability of 14-3-3 to activate exoenzyme S ADP-ribosyltransferase.

5 pparatus which is required for the export of exoenzyme S and potentially other co-ordinately regulate

6 on the levels of elastase, phospholipase C, exoenzyme S, and alkaline protease.

7 udies prove that the 53- and 49-kDa forms of exoenzyme S are encoded by separate genes.

8 Thus, exoenzyme S could interfere with host cell physiology vi

9 ion mutants were isolated which exhibited an exoenzyme S-deficient phenotype (388::Tn5Tc 469, 550, 34

10 -53 catalyzed the FAS (for factor activating exoenzyme S)-dependent ADP-ribosylation of soybean tryps

11 is the first report of the factor-activating-exoenzyme-S-dependent ADP-ribosyltransferase activity of

12 Pseudomonas aeruginosa exoenzyme S double ADP-ribosylates Ras at Arg(41) and Ar

13 s data indicated that Pseudomonas aeruginosa exoenzyme S (ExoS) ADP-ribosylated Ras at multiple sites

14 Pseudomonas aeruginosa exoenzyme S (ExoS) ADP-ribosylated Ras to a stoichiometr

15 Pseudomonas aeruginosa exoenzyme S (ExoS) ADP-ribosylates multiple eukaryotic t

16 Production of the ADP-ribosylating enzyme exoenzyme S (ExoS) by Pseudomonas aeruginosa has been as

17 d protein ligand, the ADP-ribosyltransferase Exoenzyme S (ExoS) from Pseudomonas aeruginosa.

18 Type III-mediated translocation of exoenzyme S (ExoS) into HT-29 epithelial cells by Pseudo

19 Pseudomonas aeruginosa delivers exoenzyme S (ExoS) into the intracellular compartment of

20 Exoenzyme S (ExoS) is a bifunctional Pa TTS effector pro

21 Exoenzyme S (ExoS) is a bifunctional toxin directly tran

22 Pseudomonas aeruginosa Exoenzyme S (ExoS) is a bifunctional type-III cytotoxin.

23 Exoenzyme S (ExoS) is a bifunctional virulence factor di

24 Exoenzyme S (ExoS) is a mono-ADP-ribosyltransferase secr

25 Pseudomonas aeruginosa exoenzyme S (ExoS) is a type III secretion (TTS) effecto

26 Exoenzyme S (ExoS) is an ADP-ribosyltransferase produced

27 Pseudomonas aeruginosa exoenzyme S (ExoS) is an ADP-ribosyltransferase that mod

28 Exoenzyme S (ExoS) is translocated into eukaryotic cells

29 studies reported that Pseudomonas aeruginosa exoenzyme S (ExoS) possessed an absolute requirement for

30 Type III-delivered exoenzyme S (ExoS) preferentially ADP-ribosylated membra

31 two mutations within Pseudomonas aeruginosa exoenzyme S (ExoS) showed that a E379D mutation inhibite

32 Exoenzyme S (ExoS), an ADP-ribosylating enzyme produced

33 n of 14-3-3zeta with another target protein, exoenzyme S (ExoS), an ADP-ribosyltransferase from Pseud

34 nal data suggest that Pseudomonas aeruginosa exoenzyme S (ExoS), an ADP-ribosyltransferase, is transl

35 f at least four different effector proteins, exoenzyme S (ExoS), ExoT, ExoU, and ExoY.

36 The exoenzyme S (ExoS)-producing Pseudomonas aeruginosa stra

37 two ADP-ribosyltransferases, exotoxin A and exoenzyme S (ExoS).

38 enetic relationship between the two forms of exoenzyme S, exoS (encoding the 49-kDa form) was used as

39 PAO-exsA::omega,, which lacks exoenzyme S expression, was fully virulent, causing at l

40 etained the requirement of factor activating exoenzyme S (FAS) activation for the expression of ADP-r

41 for the eukaryotic protein factor activating exoenzyme S (FAS) for expressing ADP-ribosyltransferase

42 equence similarity to the ribosyltransferase exoenzyme S from Pseudomonas aeruginosa and the cytotoxi

43 t studies predict that the amino-terminus of exoenzyme S has limited primary amino acid homology with

44 Exoenzyme S is an ADP-ribosylating extracellular protein

45 Exoenzyme S is an extracellular ADP-ribosyltransferase o

46 The production of exoenzyme S is correlated with the ability of Pseudomona

47 sion of the ADP-ribosyltransferase domain of exoenzyme S is cytotoxic to eukaryotic cells.

48 Exoenzyme S is purified from culture supernatants as a n

49 Exoenzyme S of Pseudomonas aeruginosa (ExoS) is a member

50 he 53-kDa (Exo53) and 49-kDa (ExoS) forms of exoenzyme S of Pseudomonas aeruginosa are encoded by sep

51 Exoenzyme S of Pseudomonas aeruginosa is an ADP-ribosylt

52 by ART3, ART4, ART5, Pseudomonas aeruginosa exoenzyme S, or cholera toxin A subunit.

53 ding ExsB and most of ExsB' severely reduced exoenzyme S production.

54 for ExsB and ExsB', however, did not affect exoenzyme S production.

55 cleotide sequence analysis of loci linked to exoenzyme S production.

56 388 was used to identify genes required for exoenzyme S production.

57 The exoenzyme S regulatory protein ExsA regulates a type III

58 Proteins encoded by the exoenzyme S regulon and the Yersinia Yop virulon show a

59 It will be important to understand how the exoenzyme S regulon contributes to pathogenesis and whet

60 The exoenzyme S regulon is a set of coordinately regulated v

61 Members of the exoenzyme S regulon represent only a portion of the viru

62 ogenic mutants of the Pseudomonas aeruginosa exoenzyme S regulon were compared to identify proteins c

63 e ExsA is a transcriptional regulator of the exoenzyme S regulon, chromosomal preparations from invas

64 rolled by ExsA and therefore was part of the exoenzyme S regulon.

65 in vitro cytotoxicity and expression of the exoenzyme S regulon.

66 trains were screened for their complement of exoenzyme S structural genes, exoS, encoding the 49-kDa

67 region that is co-ordinately regulated with exoenzyme S synthesis.

68 Expression of ExsC, ExsB, and ExsA (the exoenzyme S trans-regulatory locus) of Pseudomonas aerug

69 oRI fragment that is not contiguous with the exoenzyme S trans-regulatory operon.

70 t upon, exogenous FAS (for factor activating exoenzyme S), which indicated that serum contained endog

71 The carboxyl-terminal 222 amino acids of exoenzyme S, which represent the FAS-dependent ADP-ribos