ライフサイエンスコーパス: expand

1 In others, HSPCs expand.

2 sed ways in which the model could be further expanded.

3 aphy (EEG) use in critically ill patients is expanding.

4 We expanded a previously published Bayesian synthesis frame

5 (3D) hydrogels is an attractive strategy for expanding a therapeutically relevant number of stem cell

6 on within different Norovirus genogroups and expands a growing knowledge base on the interaction betw

7 matrix metalloprotease ZMP-1 and transiently expands AC volume by more than 20%, displacing surroundi

8 ource settings could decrease user error and expand access to lifesaving outpatient antibiotic treatm

9 al tiered laboratory networks and systems to expand access to reliable, high-quality testing across c

10 er (OUD) in U.S. primary care settings would expand access to treatment for this condition.

11 nsed rVSV-ZEBOV vaccine was introduced under expanded access, the first time that an Ebola vaccine ha

12 botulism who were treated with HBAT under an expanded-access Investigational New Drug program.

13 est Mediterranean Neolithic indicate that it expanded across 2,500 km in about 300 y.

14 sity, involves immune cell infiltration into expanding adipose tissue.

15 oduction of Cas9-directed genome editing has expanded adoption of this approach.

16 our of the patients were found to possess an expanded allele, which was associated with a reduction i

17 en the amount of inhaled allergen is low, by expanding allergen-specific T cells.

18 Conclusion This expanded analysis further characterizes the importance o

19 aring the foveal center, and over time often expand and coalesce to include the fovea.

20 lymphoid tissues where self-reactive B cells expand and differentiate.

21 Invaded species often can rapidly expand and establish in novel environments through adapt

22 Our approach relies on an expanded and curated set of viral protein families used

23 These can be expanded and differentiated to form an epithelial layer

24 At climatic boundaries where mangroves are expanding and replacing salt marsh, wetland capacity to

25 Exogenous R-spondin administration expands and accelerates proliferation of Axin2(+)/Lgr5(-

26 s new projects are developed and the network expands and grows to address the ever-changing prioritie

27 A strategy to expand anti-Stokes shifting from the far-red to deep-blu

28 However, to expand applications to oncology, critical limitations of

29 e in developing new therapeutic proteins and expanding applications of existing therapeutic proteins.

30 The expanded aptamer-based proteomic platform provides a uni

31 Expression of polyglutamine-expanded AR causes damage to motor neurons and skeletal

32 nce of improving awareness of HIV status and expanding ART to prevent losses in HRQoL that occur with

33 n, applications of the CRISPR/Cas system are expanding at a breath-taking pace and are revolutionizin

34 e targeted topical and systemic therapies is expanding based on our growing understanding of the mech

35 The new Expanded-Baveno VI criteria spare more endoscopies than

36 This cross-functional compatibility expands between the metazoan and plant kingdoms, illustr

37 on data, query-based biclustering, bicluster expanding, biclusters comparison, heatmap visualization

38 ng of PSMA ligand PET are evolving given the expanding body of literature on physiologic and patholog

39 number of older people with care needs will expand by 25% by 2025, mainly reflecting population agei

40 from multiple methods have been improved and expanded by integrating the precise Islander method for

41 ,eta(5:5)-As5)][BF4] (5), which is a product expanded by one arsenic atom, instead of the expected co

42 es the radiation of the seed plants and then expanded by subsequent polyploidy events.

43 development of natural Th1 cells, which are expanded by the presence of IL4.

44 Huntington's disease (HD) is caused by an expanded CAG repeat in the Huntingtin (HTT) gene.

45 e findings provide evidence that breakage at expanded CAG repeats occurs due to R-loop formation and

46 Lastly, we leverage the expanded capabilities of YcaO proteins to conduct an ext

47 As a result of the expanding catalog of metagenomic viral sequences, there

48 quences that were derived from such clonally expanded CD4+ T cells constituted 62% of all analyzed ge

49 lminth infection have contributed toward our expanding cellular and molecular understanding of type-2

50 Finally, we utilized the expanded cerebral organoids to show that infection with

51 Histology revealed dramatically expanded cervical cementum in GACI teeth, including ceme

52 molecular studies have both transformed and expanded classical concepts of receptor pharmacology and

53 The best new expanded classification rule was platelet count >110 x 1

54 nal mutational hits (2nd Hit) transforms the expanding clone into cancer.

55 Expanded clones from two T1D subjects recognized distinc

56 Moreover, many, and partly very large, expanded clones were seen predominantly among IgM(+) mem

57 A further 114 infants were enrolled in the expanded cohort between Nov 3, 2014, and March 20, 2015,

58 Synthetic biology offers the potential to expand communication 'bandwidth' by using biomolecules a

59 ordered proteins can attain both compact and expanded conformations, and the level of expansion may b

60 ctronic structures and optical properties of expanded, contracted, and isomeric porphyrins is describ

61 d fully implemented in 2014, was intended to expand coverage and bring about a new era of health-care

62 Methods expanding coverage of the lipidome increase the likeliho

63 Use of expanded criteria donor (ECD) kidneys, which are associa

64 It is caused by expanded CTG repeats in the 3'-UTR of the dystrophia myo

65 Expanded data content is mostly genomic and functional g

66 urnals indexed in the Science Citation Index Expanded database.

67 ians to embrace the increased complexity and expanded decision algorithms and therapeutic options tha

68 Health and eye-care practitioners need to expand diabetic health education and promotion among dia

69 its of success, but lifespan extension might expand disability of physical and cognitive functioning

70 sNfL was independently associated with Expanded Disability Status Scale (EDSS) assessments (bet

71 d DMD exposure decreased the risk of a first Expanded Disability Status Scale (EDSS)-worsening event

72 Clinical disability scores (Expanded Disability Status Scale [p = 0.009] and Institu

73 total relapses averaged 4 +/- 2.4, and their Expanded Disability Status Scale was 2.7 +/- 0.5.

74 dy of membrane-bound interleukin 21 (mbIL21) expanded donor NK cells infused before and after haploid

75 This work greatly expands doping chemistry for tailoring the structures of

76 MDSCs expand during the later phases of sepsis in mice, promot

77 D16(+) monocyte population was significantly expanded during ZIKV infection compared to uninfected co

78 and QI projects allowed diverse findings to expand each other and identify gaps between research and

79 osynthesis and photoprotection, including an expanded family of high-light-inducible (ncHLI) proteins

80 The rapidly expanding field of nonaqueous multivalent intercalation

81 early burst" model, morphospace continued to expand following a slowdown in rates.

82 se advances, the role of cardiac imaging has expanded from a largely diagnostic tool to an adjunctive

83 ls were successfully isolated, cultured, and expanded from eight 20-mm, 18-gauge hepatic core samples

84 ture system, MART1-specific CD8 T cells were expanded from healthy donors using artificial APCs.

85 In vivo, only cells expanded from PD-1(+) CD8 TILs contained tumor progressi

86 ies, including current adoption barriers and expanded future demands based on demographic and market

87 ers than progressors (P = 0.0001), and these expanded Gag-specific CD4(+) T cells in HIV controllers

88 Expanded GGGGCC repeats in the first intron of the C9orf

89 ger-scale microbial genomics analysis, while expanding GI predictions and improving its flexible visu

90 he diverse sequences identified here did not expand globally.

91 ly generated cysLTs induced eosinophilia and expanded group 2 innate lymphoid cells (ILC2s) in aspiri

92 and cell culture-compatible marker of UM171-expanded human cord blood HSCs.

93 re because drought, rising temperatures, and expanding human populations are increasing water demands

94 ic responses and placental development in DC expanded IL-10(-/-) dams.

95 When expanding illness outcome to include SZ spectrum disorde

96 contrast to the expectation that ice sheets expand in colder climates and shrink in warmer climates.

97 ine receptor required for homing to GCs) and expand in lymph nodes (LNs) following pathogenic SIV inf

98 e propose that autoreactive TH1/TH17CM cells expand in patients with MS and promote relapses after by

99 Group 2 innate lymphoid cells (ILC2s) expand in the lungs of mice during type 2 inflammation i

100 m the patient's peripheral blood T cells and expand in the recipient to eliminate the targeted tumor.

101 enerating such grafts are easy to obtain and expand in vitro.

102 ogenitor cells could be isolated and ex vivo expanded in a reproducible manner.

103 CD3/28-activated T cells expanded in IL-7 and IL-15 produced greater expansion of

104 pos)HLA-DR(low/neg) monocytic (M)-MDSCs were expanded in intensive care unit patients with and withou

105 ion against new tumors and was significantly expanded in patients responding to immunotherapy.

106 ranulocytic (G)-MDSCs were more specifically expanded in patients with sepsis (P < 0.001).

107 he context of a hexadecameric complex can be expanded in the future to the other 7 subunits that form

108 and SA CMCs were isolated from mouse hearts, expanded in vitro, characterized, and evaluated for ther

109 The alarmin family has been expanding in terms of both number and the concept.

110 The International Genome Sample Resource expands in data type and population diversity the resour

111 of neuromuscular junctions are dramatically expanded, including the subsynaptic reticulum, the posts

112 nd the potential for self-administration can expand influenza vaccination coverage in developing coun

113 Data sharing is as an expanding initiative for enhancing trust in the clinical

114 lar lifestyle during which bacteria clonally expand into multicellular bacterial communities within t

115 ction from the use of ITNs during pregnancy, expanding IPTp-SP to all women with >/=3 ANC visits in A

116 ancer, a predictive mathematical model of an expanded iron homeostasis pathway was constructed that i

117 Here we use an expanding island of confluent Madin-Darby canine kidney

118 amentarium of pharmacologic asthma therapies expands, it will be critical to include elderly asthmati

119 ca, a globally distributed passerine [4, 5], expanded its breeding range an exceptional 7,000 km when

120 ating demand for polio vaccination but later expanded its messaging to promote routine immunization a

121 dophlebiomorpha during the Late Triassic and expands its distribution and diversity in Asia.

122 e, we describe a protocol for generating and expanding large numbers of homogeneous midbrain floor pl

123 As expected, the GGA yields expanded lattices and softened bonds in relation to the

124 Using proteomic analyses of expanding leaves of corn (Zea mays L.), we show that thi

125 Most (87%) top expanded lesional T-cell clones were shared with nonlesi

126 bservation that function can be derived from expanded, low density protein states has broad implicati

127 The need to expand malaria diagnosis capabilities alongside policy r

128 -to-cell infection when host populations are expanded massively through fungiculture.

129 observed variability suggesting the need for expanded measurements in the future.

130 We demonstrate that expanded mFPPs have increased DA neuron potential and di

131 Using this approach, we expanded minor clones and obtained epithelial cell-speci

132 ranscatheter, transapical delivery of a self-expanding mitral valve prosthesis and were examined in a

133 vances in enzyme engineering and design have expanded nature's catalytic repertoire to functions that

134 The auditory cortex selectively expands neural representations of enriched acoustic stim

135 ter heart valve (THV) is a low-profile, self-expanding nitinol valve made from bovine pericardial tis

136 and safety of infusing high doses of ex vivo-expanded NK cells after haploidentical HSCT without adve

137 ls ex vivo, it remains unknown whether these expanded NK cells can persist and/or proliferate in vivo

138 to efficiently generate large quantities of expanded NK cells ex vivo, it remains unknown whether th

139 e results support the application of ex vivo expanded NK cells in cancer immunotherapy and provide a

140 HVEM-deficient CD8 T cells expanded normally but were skewed away from MPECs with r

141 We confirmed and expanded observations in mice that variations in dietary

142 In this systematic review, we expand on previous reviews of obesity prevention interve

143 Using in situ autophosphorylated protein, we expand on the known set of CPK28 autophosphorylation sit

144 We expanded on a series of pyrido[2,1-f]purine-2,4-dione de

145 In this investigation, we expanded on these studies by generating Atp7a(LysMcre) m

146 ntly introduced MethylationEPIC (EPIC) array expands on the utility of this platform, but has not yet

147 rsonal Viewpoint essay, we argue in favor of expanding one such pilot project-the Comprehensive ESRD

148 ary human healthy liver cells form long-term expanding organoids that retain liver tissue function an

149 We expand our calibration to high ligand concentrations and

150 These efforts expand our understanding and ability to interrogate both

151 ue-induced reinstatement of alcohol seeking, expand our understanding of how the BLA-->NAc pathway re

152 These insights expand our understanding of the drivers of the evolution

153 To expand our understanding of the uncommon entity, referre

154 ical examination of these interactions could expand our understanding of viruses and be exploited for

155 These findings expand our view of how tRNA, and possibly the genetic co

156 veral decades, numerous studies have greatly expanded our knowledge about how microtubule organizatio

157 This study not only expanded our knowledge on novel sRNAs but would also giv

158 to opportunistic mycoses have significantly expanded our understanding of the innate and adaptive im

159 of thousands of noncoding RNAs (ncRNAs) has expanded our view on mammalian genomes and transcriptome

160 New sequencing techniques are expanding our ability to agnostically interrogate nuclei

161 diators of tardigrade desiccation tolerance, expanding our knowledge of the roles and diversity of di

162 Expanding our understanding of the burden AKI has on the

163 of the structural complexity of networks and expands our understanding of complex network behavior.

164 This work further expands our understanding of this complex multifaceted t

165 isation, but the ranges of transient species expanded over the long-term, slowly increasing their reg

166 ntering range in Argentina [6], subsequently expanding over 500 km from its starting point [7-11].

167 They are constructed from expanded oxide rows with a lattice constant close to tha

168 mployed transgenic overexpression of alanine-expanded PABPN1.

169 with observations in other species, but with expanded pairing rules.

170 A major impediment to expanding PET applications to study the brain has been t

171 To describe an expanded phenotypic spectrum and longitudinal outcome in

172 Here we describe spectacular extremely expanded, pod-like tibiae in males of a platycnemidid da

173 velopment of a mounted warrior elite able to expand polities (political units that cohere via identit

174 gregation of huntingtin protein arising from expanded polyglutamine (polyQ) sequences in the exon-1 r

175 This approach revealed a markedly expanded population of PD-1(hi)CXCR5(-)CD4(+) T cells in

176 stantaneously (seconds) convert into rapidly expanding pores causing membrane lysis (minutes).

177 Porphyrins and expanded porphyrins have attracted the attention of chem

178 izes generally contracted pre-extinction and expanded post-colonisation, but the ranges of transient

179 Here we report that cultures of expanded potential stem cells can be established from in

180 s highlights the feasibility of establishing expanded potential stem cells for other mammalian specie

181 The generation of mouse expanded potential stem cells highlights the feasibility

182 The second decade expanded PPC oncology investigation to include the entir

183 d that vaccination with neoantigens can both expand pre-existing neoantigen-specific T-cell populatio

184 Studies of universal treatment and expanded prevention of HIV differ widely in their projec

185 acity support is provided to the South Sudan Expanded Program on Immunization by STOP volunteers, imp

186 o assist in this transition, the South Sudan Expanded Program on Immunization human resources develop

187 ce by influencing compensatory signaling and expanding proliferation.

188 uld lead to new biological functions such as expanding protein chemistries with noncanonical amino ac

189 correcting the conformation of polyglutamine-expanded proteins as well as the pharmacodynamics readou

190 With the number of cancer survivors expanding quickly, the time has come for cardiologists t

191 photovoltaic (PV) electricity generation is expanding rapidly in China, with total capacity projecte

192 echanistic understanding of CARs was used to expand reaction scope, generating biocatalysts for amide

193 monas aeruginosa strain PA14 and an updated, expanded reconstruction of P. aeruginosa strain PAO1.

194 rane-associated proteins, Kibra, Merlin, and Expanded, regulate pathway activity, but the precise mol

195 Our results underscore the significance of expanding residential development on mule deer populatio

196 Identification of this phenotype expands risk stratification and can lead to effective tr

197 the care of MPM patients with a focus on the expanding role of MMT in MPM.

198 To describe the expanding role of telemedicine in healthcare, the key cr

199 The ability to genetically encode an expanded set of building blocks with new chemical and ph

200 our predictions about how human actions are "expanding", "shrinking", "speeding up" and "slowing down

201 ds for detection of DNA and RNA targets have expanded significantly in recent years, promising a new

202 ipotency-expressing OCT4 + and NANOG + cells expanded sooner in AhR-/- than in AhR+/+ regenerating li

203 estis has adopted a regenerative strategy to expand stem cell activity by incorporating a transit-amp

204 ation and the data upon which it relies have expanded substantially in the twenty-first century.

205 the unfolded form at low temperature is more expanded than the corresponding one at high temperature.

206 In total, our findings expand the biological coordination chemistry of Ni(II)-c

207 Collectively, we expand the catalog of ubiquitylation targets in Arabidop

208 Our findings expand the clinical and molecular spectrum of metabolic

209 These findings further expand the existing repertoire of genes involved in ARID

210 r on the horizon will continue to evolve and expand the footprint of telemedicine within ophthalmolog

211 han lightning-started fires, thereby helping expand the geographic and seasonal niche of wildfire.

212 Moreover, these data also significantly expand the known functions of smORF-encoded microprotein

213 These results expand the model of insulin-stimulated glucose uptake in

214 Building on this success, CRACKLE II will expand the network to hospitals across the United States

215 policy." SLT is an established procedure to expand the organ pool and reduce wait list mortality; ho

216 We further expand the phenotypic spectrum of KMT2B-related disorder

217 We expand the photoactivatable chemistry toolbox here with

218 The results expand the range of emission properties that can be achi

219 ersity of genomes, the content of which will expand the repertoire of microbe-based biotechnologies.

220 the scope of the peroxide stress regulon and expand the repertoire of oxidative stress genes in S. mu

221 These findings expand the repertoire of vertebrate trunk neural crest c

222 Together, our findings expand the role of SLC13A5 from facilitating hepatic ene

223 cal and broadly applicable strategy that can expand the scope of catalyst-controlled stereoselective

224 gical developments in 2D IR that continue to expand the scope of scientific problems that can be acce

225 ltiple network alignment (MNA) approaches to expand the search space of protein complex detection.

226 ecific non-covalent interactions can greatly expand the structural and functional space of supramolec

227 These findings expand the structural and mechanistic repertoire of flav

228 we show in our separate report, may help to expand the therapeutic spectrum of HU to additional path

229 proaches for the use of this data promise to expand the use of pressure-guided heart failure manageme

230 Our results expand the utility of thiolase-based pathways and provid

231 This shows that Cas9 variants can be used to expand the utility of this technology.

232 n the basis of emerging findings, we further expanded the 120 mg and 200 mg dose cohorts to include F

233 Mass cytometry (CyTOF) has greatly expanded the capability of cytometry.

234 transcriptome sequencing efforts have vastly expanded the catalog of long non-coding RNAs (lncRNAs) w

235 To close this gap, we have significantly expanded the database for comparative genomics studies i

236 n unexpected twist, King and colleagues have expanded the repertoire of prokaryotic influence over eu

237 ecay, initially seen as a detriment, has now expanded the scope of plasmonic applications to exploit

238 a forepaw stimulus of a particular frequency expanded the sensory representation of that stimulus, no

239 Humans have vastly expanded the spatial and seasonal "fire niche" in the co

240 peptides with diverse modifications thereby expanding the accessible chemical space and reducing syn

241 solvent accessibility of the active site by expanding the active site volume, allowing additional wa

242 multi-gene restriction-modification module, expanding the arsenal of defence systems known to be at

243 We aimed at expanding the Baveno VI criteria and validating them in

244 Expanding the chemical diversity of TNA beyond the natur

245 ombination seems to be a feasible option for expanding the donor pool without additional donor risks.

246 circular RNAs may generate proteins, thereby expanding the eukaryotic proteome and revealing novel mo

247 s and nanostructures plays a seminal role in expanding the frontiers of quantum materials.

248 s design considerations and technologies for expanding the genetic code.

249 rate continuous-wave lasing from CQD solids, expanding the library of solution-processed materials th

250 s from 10 countries and territories, greatly expanding the observed viral genetic diversity from this

251 or to monitor tissue changes over time, thus expanding the range of questions that can be addressed i

252 overall energy requirements thereby greatly expanding the range of semiconductors that can be utiliz

253 field excitation enhances temporal coding by expanding the range of theta phase precession.

254 acrocyclic structures, thereby significantly expanding the scope and complexity of ChB host systems,

255 nded a previously described motif (4 x 5) by expanding the structure to a system that links four doub

256 he protospacer adjacent motif (PAM), thereby expanding the target range of Cpf1-mediated genome editi

257 biogas upgrading technology and potentially expands the application of microbial electrochemical tec

258 emonstrates the validity of our approach and expands the arsenal of the crystallization chaperone too

259 Moreover, the new technique significantly expands the capability of protein structure modeling and

260 This study further expands the catalog and properties of organic salts for

261 Prep1 DR expands the DNA binding landscape of C/EBPbeta (CCAAT en

262 Our study further expands the mutational spectrum of this gene and the ass

263 This study expands the structure-activity relationships on our orig

264 Streptococcus pyogenes Cas9 (SpyCas9), which expands the temperature range for CRISPR-Cas9 applicatio

265 dation for improved RNP delivery in vivo and expands the temperature range of CRISPR-Cas9.

266 Jurassic-Cretaceous extinction boundary and expanded their known range, at least, into western North

267 Moose (Alces alces) have expanded their range southward into agricultural areas p

268 h with prey species was enhanced by warming, expanding their importance as predators in this system.

269 enhances their decision-making accuracy and expands their behavioral repertoire.

270 to Thailand between 1979 and 1982, and began expanding there shortly afterwards (1982-1984).

271 cipants and thereby avoids the need to first expand these into multiple binary interactions.

272 In a second step, we selectively expanded this curated map with database knowledge.

273 We have now expanded this study to evaluate the efficacy of PD-1 blo

274 emand is required for sanitation coverage to expand through private provision.

275 Thus, gene amplification can be acquired and expanded through parallel evolution, enabling tumors to

276 ature window for their calcification will be expanded throughout much of the year.

277 of large, invasive cellular protrusions that expand tiny basement membrane openings.

278 t utilizes magnesium monochloride cations in expanded titanium disulfide.

279 If the base-level Spillway Lake continues to expand to a fully formed moraine-dammed glacial lake, th

280 ntestinal crypts from Cd44(-/-) mice did not expand to the same extent as crypts from Cd44(+/+) mice

281 t the general concept of the native state be expanded to allow for more variable physical dimensions

282 Our simple model, when expanded to complex microecological association studies

283 ersonalized cell therapies since they can be expanded to generate large numbers of cells and differen

284 ectrum of the m.3243A > G mutation has since expanded to include a spectrum of neuromuscular and ocul

285 table behavior over multiple years and never expanded to the point of dominance or dysplasia.

286 This safe and effective approach expands treatment options and should be considered as a

287 udies suggest that a discrete DC subset both expands Tregs and suppresses CD8 T cells to establish an

288 f familial PCA for clinical genetic testing, expanding understanding of genetic contribution to aggre

289 n intermediates and mature effector cells to expand upon demand, thereby providing lifelong immunity.

290 he role of MT in vRNA transport and assembly expand upon previous studies characterizing vRNA assembl

291 he Great Basin treeline for these species is expanding upslope with a mean vertical elevation shift o

292 As policy discussions for the expanded use of RTS,S/AS01 continue, it will be critical

293 Tregs expanded using soluble OX40 L and JAG1 were of suppressi

294 In vivo, expanding vessel networks favor interactions with Flt1 m

295 Recent federal policy changes attempt to expand veterans' access to providers outside the Departm

296 These results present an expanded view of the Parcubacteria, among members residi

297 Accelerated mortality was not due to expanded viral tropism or increased replication.

298 Expanding wetland area with saturated and warmer organic

299 Vessel networks expand when sprouts form new connections, a process whos

300 establish durable commensal populations that expanded with human societies.