ライフサイエンスコーパス: expand @1 understanding of

1 Expanding our understanding of activation signals drivin

2 xcavation at Tikal, Guatemala, have markedly expanded our understanding of ancient Maya water and lan

3 anscriptional gene regulatory mechanisms has expanded our understanding of angiogenesis in physiologi

4 OCT technology is expanding our understanding of angle closure disease.

5 These results significantly expand our understanding of antagonist binding sites on

6 nce resolution of a standing controversy and expand our understanding of AQP1 as a multifunctional re

7 Further research to expand our understanding of astringent perception and it

8 del of the Act-EF34/palladin peptide complex expands our understanding of binding specificity between

9 amically complex cellular systems, will help expand our understanding of biological processes and ope

10 ated" NLRs can function as pathogen sensors, expanding our understanding of both receptor architectur

11 clinical detection of this inflammation will expand the understanding of BPH pathogenesis and its his

12 EC3 family of innate restriction factors and expands the understanding of C>U RNA editing in mammals.

13 MicroRNAs (miRs) are expanding our understanding of cardiac disease and have

14 To expand our understanding of catalysis by this class of e

15 Our studies expand our understanding of cavitation and provide new i

16 orphology of sacrificial templates, but also expands our understanding of chemical transformations in

17 o child maltreatment continue to improve and expand our understanding of child abuse pediatrics.

18 Recent attempts to expand our understanding of circadian regulation have mo

19 rker in epilepsy in gray matter heterotopia, expand our understanding of circuit mechanisms of epilep

20 Advances in human genetics have dramatically expanded our understanding of complex heritable diseases

21 of the structural complexity of networks and expands our understanding of complex network behavior.

22 In the last few years, studies have expanded our understanding of demographic and presenting

23 uctive, and repeated imaging is necessary to expand our understanding of disease progression and regr

24 identify currently undiagnosed patients and expand our understanding of disease spectrum.

25 ruption of downstream cellular pathways have expanded our understanding of disease pathogenesis in sy

26 evelopments of unique nucleotide probes have expanded our understanding of DNA polymerase function, p

27 Collectively, our findings expand our understanding of DV's mechanism of action on

28 draws on developmental psychology theory to expand the understanding of early moral behaviours.

29 lated genes and EC-interacting proteins have expanded our understanding of EC function.

30 c properties from enamel with known genotype expands the understanding of enamel formation processes

31 Elucidating the underlying mechanisms will expand our understanding of endothelial dysfunction and

32 inical trials and experimental evidence that expand our understanding of Epo as a potential treatment

33 The complete genome has also greatly expanded our understanding of ET-743 production and reve

34 loviruses, but recent outbreaks have greatly expanded our understanding of filovirus immune responses

35 of FzlC as a novel membrane anchor for FtsZ expands our understanding of FtsZ regulators and establi

36 These tools can expand our understanding of fundamental biological proce

37 Recent studies have expanded our understanding of gating pore current as a d

38 esearch on long noncoding RNAs (lncRNAs) has expanded our understanding of gene transcription regulat

39 us genes in mice and medaka fish and further expands our understanding of genetic contributions to la

40 Our study expands the understanding of genetic factors influencing

41 However, recent reports have greatly expanded our understanding of GILT's function.

42 spatial, temporal and taxonomic scales, are expanding scientific understanding of global infectious

43 These findings significantly expand our understanding of hemoglobin iron acquisition

44 put sequencing (HTS) and bioinformatics have expanded our understanding of herpesviruses through geno

45 Our study expands the understanding of Hh signaling in the animal

46 Our data expand our understanding of how a single neuroendocrine

47 und to be made in the coming years that will expand our understanding of how AT stands at the junctio

48 These data expand our understanding of how endocrine inhibin achiev

49 These observations significantly expand our understanding of how environmental factors in

50 These findings expand our understanding of how evolution driven by inte

51 ientific framework, we have the potential to expand our understanding of how experience molds the bra

52 In this issue, Vijayaraj et al. expand our understanding of how keratin proteins partici

53 This work may expand our understanding of how KSHV evades host inflamm

54 and inhibits KSHV replication, this work may expand our understanding of how KSHV evades host inflamm

55 o iron fertilization experiments and further expand our understanding of how phytoplankton adapt to v

56 ue-induced reinstatement of alcohol seeking, expand our understanding of how the BLA-->NAc pathway re

57 These results expand our understanding of how the orbitofrontal cortex

58 io-temporally controlled ROS generation will expand our understanding of how the respiratory chain an

59 us-RNA incorporation.IMPORTANCE Our findings expand our understanding of how viruses utilize capping,

60 dies using a model IRES from dicistroviruses expanded our understanding of how a 3D RNA structure can

61 s have been identified, recent findings have expanded our understanding of how context, in particular

62 n-dependent nucleation of actin cables, thus expanding our understanding of how specific tropomyosin

63 ment of antibiotics and immune modulators by expanding the understanding of how PG is processed by ly

64 in which NF-kappaB is regulated and greatly expands our understanding of how MCV so effectively evad

65 Importantly, this work expands our understanding of how PIV-3 effectively evade

66 This finding expands our understanding of how platelets attach to sit

67 sh a cogent structure-function paradigm that expands our understanding of how RNA structure can enhan

68 ator of AMPAR-mediated neurotransmission and expands our understanding of how ubiquitination dynamica

69 undergoes activity-dependent ubiquitination expands our understanding of how ubiquitination regulate

70 repair of damaged DNA.IMPORTANCE This study expands the understanding of HPV biology, establishing a

71 cultivated mushrooms, and model systems that expand our understanding of human disease.

72 Two very different studies expand our understanding of human skin aging.

73 otherapies have created a compelling need to expand our understanding of human T cell function and ma

74 cing of individual human genomes has greatly expanded our understanding of human genetic variation an

75 These findings expand our understanding of ILC2 regulation and may have

76 To expand our understanding of Inc function(s), we subjecte

77 o the conceptual tool kit of immunology will expand our understanding of infectious diseases and host

78 is of the critical host response has greatly expanded our understanding of infectious diseases.

79 and other genetically tractable insects, has expanded our understanding of innate immunity and more r

80 Fundamentally, such measurements expand our understanding of intrinsic intramolecular fol

81 The increased number of molecules expands our understanding of isoform complexity.

82 metabolic control point in the EMC pathway, expanding our understanding of its regulation.

83 or regulation of insulin gene expression and expands our understanding of its role in the beta cell.

84 This approach has the potential to expand our understanding of kinase-substrate connections

85 Collectively, our data expand our understanding of longer epitopes in the conte

86 y, a number of studies have both refined and expanded our understanding of LSCs and intrapatient hete

87 siology and neurobiology of ejaculation have expanded our understanding of male sexual function and h

88 These studies have greatly expanded our understanding of mechanisms underlying the

89 ortex and cerebellum of an affected proband, expanding our understanding of mechanisms attributed to

90 r -omic approaches provides opportunities to expand our understanding of microbial metabolic networks

91 A recent paper in Nature by Davis et al. expands our understanding of miRNA biogenesis and matura

92 Invertebrate animal models of SCA6 can expand our understanding of molecular sequelae related t

93 repress muscle development, and this result expands our understanding of muscle development mechanis

94 thesis of these complex lipids will not only expand our understanding of mycobacterial cell wall bios

95 f the PGL biosynthetic pathway will not only expand our understanding of natural product biosynthesis

96 ntify genes for industrial engineering while expanding our understanding of natural diversity.

97 l modifications, providing opportunities for expanding our understanding of nature's chemical and bio

98 Our data expand the understanding of neurexin-based transsynaptic

99 tion of novel virulence factors, has rapidly expanded our understanding of niche adaptation in Vertic

100 Our findings expand our understanding of NLS as a disorder of the L-s

101 and [Ca(2+)]i, neuroscientists are poised to expand the understanding of noncanonical roles of sodium

102 th solidified previously held assertions and expanded our understanding of Notch function during neur

103 Recent data have expanded our understanding of Notch signalling by identi

104 The combined studies expand our understanding of NPP1 and NPP4 substrate spec

105 different views has the potential greatly to expand our understanding of oculomotor control and our a

106 Importantly, our findings expand the understanding of one of the central component

107 These findings expand our understanding of oocyte biology and clarify m

108 psychology and behavioral neuroscience have expanded our understanding of other reward-related proce

109 This work expands our understanding of parasite adaptation to drug

110 or barcodes to assess transmission dynamics, expanding our understanding of pathogen-host interaction

111 finding is particularly important because it expands our understanding of pathogen adaptation to mode

112 ion in B. glabrata provides a foundation for expanding our understanding of pathways and genes involv

113 In addition, this document is intended to expand the understanding of patient risk stratification

114 Collectively, this work expands our understanding of peptide-mediated signaling

115 the molecular architecture of the human OX2R expands our understanding of peptidergic GPCR ligand rec

116 These findings expand our understanding of peroxisome division and pote

117 This novel mechanism expands our understanding of PKS assembly-line catalysis

118 t of scholarship utilizing genetic models to expand the understanding of political traits has emerged

119 These findings expand our understanding of PPARgamma activation by liga

120 This work expands our understanding of prenylation's impact within

121 ng a new three-level annotation that greatly expands our understanding of prokaryotic genomes.

122 relevant to the role of AP-5 in neurons and expands the understanding of recessive HSPs.

123 We sought to expand the understanding of relationships of influenza o

124 f these genetic factors will be critical for expanding our understanding of renal development and fun

125 These findings expand our understanding of sensorineural plasticity in

126 e a generalizable workflow to explore sHsps, expand our understanding of sHsp structural motifs, and

127 tinct from previously described models, thus expanding our understanding of signal transduction acros

128 The findings in this study expand our understanding of SRPS locus heterogeneity and

129 To expand our understanding of substrate loading, polyketid

130 These findings expand our understanding of symbiont ecology and evoluti

131 can recombine to confer Ag specificity, thus expanding our understanding of T cell biology and TCR di

132 s new insights into the pathogenesis of ACD, expanding the understanding of T-cell activation and ass

133 Recent studies have significantly expanded our understanding of TDP-43 physiology.

134 These findings expand our understanding of the ALS genetic landscape an

135 As we move forward, we need to expand our understanding of the association between the

136 physiological and pathogenic states further expand our understanding of the biological repertoire of

137 rgue that these models hold the potential to expand our understanding of the brain by connecting thes

138 These findings significantly expand our understanding of the catalyst structure in th

139 Together, these findings significantly expand our understanding of the cell-cycle-dependent rol

140 y contain a second mannose binding site, and expand our understanding of the characteristics that can

141 and potency of rosette-modulating molecules, expand our understanding of the complex chemical ecology

142 These findings expand our understanding of the components involved in H

143 e naturally occurring structural variants to expand our understanding of the consequences of diverse

144 molecular pathogenetic links should further expand our understanding of the disease.

145 e cytochrome b(6) f complex, was selected to expand our understanding of the diversity and ecology of

146 iew provides an update of ongoing efforts to expand our understanding of the diversity inherent withi

147 These insights expand our understanding of the drivers of the evolution

148 Taken together, these results expand our understanding of the early stages of the squi

149 ed as a reliable guide to cancer therapy and expand our understanding of the effects of gene alterati

150 rections for research in this area that will expand our understanding of the epigenetic changes under

151 These findings expand our understanding of the function of TPL2 as a ne

152 These results expand our understanding of the functional repertoire of

153 ntegration of systems biology is expected to expand our understanding of the genetic architecture of

154 To expand our understanding of the genetic basis of A. baum

155 lective HDAC inhibitors would therefore help expand our understanding of the HDAC enzymes and represe

156 These results expand our understanding of the hippocampal ensemble dyn

157 ful tool to go beyond genome predictions and expand our understanding of the important family of smal

158 These results expand our understanding of the involvement of the CpxRA

159 Taken together, our novel findings expand our understanding of the key mechanisms underlyin

160 a novel role for Ctsba in morphogenesis and expand our understanding of the maternal regulation of d

161 These studies expand our understanding of the mechanism by which ambie

162 ngs may lead to new treatment modalities and expand our understanding of the mechanism of action of a

163 These findings expand our understanding of the mechanism(s) involved in

164 These data expand our understanding of the mechanisms controlling p

165 These findings expand our understanding of the mechanisms involved in m

166 Collectively, these findings expand our understanding of the mechanisms of iNKT cell

167 These findings expand our understanding of the mechanisms that underlie

168 These results expand our understanding of the mechanisms underlying me

169 odularization and rationalization, which may expand our understanding of the metabolic potential of M

170 actors are intracellular targets of LeTx and expand our understanding of the molecular action of LeTx

171 This should expand our understanding of the molecular basis of natur

172 rvival of f10(-/-) mutants will enable us to expand our understanding of the molecular mechanisms of

173 These results expand our understanding of the molecular mechanisms of

174 We expand our understanding of the molecular mechanisms tha

175 To expand our understanding of the molecular mechanisms via

176 o their disease has the potential to greatly expand our understanding of the most lethal stage of thi

177 ntage points of genetics and archaeology can expand our understanding of the nature of evolutionary s

178 ynamic RSN properties are closely linked and expand our understanding of the neural architectures tha

179 Answering such a fundamental question will expand our understanding of the neural mechanisms underl

180 Our data expand our understanding of the neuronal functions of DY

181 These results dramatically expand our understanding of the organization of miRNA-en

182 These findings expand our understanding of the pathobiology of PH in HF

183 manifestations of demyelination in sEAE will expand our understanding of the pathophysiological mecha

184 Ongoing research continues to expand our understanding of the pathophysiology of persi

185 Ongoing research continues to expand our understanding of the pathophysiology of rare

186 These data expand our understanding of the phenotypic spectrum of d

187 glutathione dynamics and transportation and expand our understanding of the physiological and pathol

188 Collectively, these studies help to expand our understanding of the physiologically importan

189 These discoveries expand our understanding of the pleiotropic effects of t

190 These results expand our understanding of the posttranslational modifi

191 To expand our understanding of the potential genetic range

192 These data expand our understanding of the prediction of treatment

193 and SH3-SH2 connector in Abl regulation and expand our understanding of the principles of modular do

194 More broadly, our findings expand our understanding of the principles that govern t

195 ectively, the present findings significantly expand our understanding of the regulation of cardiac HO

196 Here we report findings that expand our understanding of the regulation of expression

197 These findings expand our understanding of the regulation of LINC compl

198 Our findings expand our understanding of the regulatory mechanisms fo

199 These findings expand our understanding of the relationship between inf

200 distinguish it from related concepts, and to expand our understanding of the relative meaning of best

201 With this review, we aim to expand our understanding of the role of CIN in cancer an

202 ch on these new discoveries will undoubtedly expand our understanding of the role of EPCR in normal p

203 In the current study, we expand our understanding of the role of matrix metallopr

204 derpinning GCN5L1 mediated ROS signaling may expand our understanding of the role of mitochondria in

205 These results further expand our understanding of the role of the Y chromosome

206 To expand our understanding of the role of this DC populati

207 In this study, in order to expand our understanding of the role of VHL in chondroge

208 peutic strategy to treat type-2 diabetes and expand our understanding of the roles of IDE in glucose

209 This study emphasizes the need to expand our understanding of the roles played by pro-apop

210 on the mechanism of RNase P and continue to expand our understanding of the structure and architectu

211 nt nanoparticles within mammalian cells will expand our understanding of the structure/function relat

212 These results expand our understanding of the substrate specificity an

213 To expand our understanding of the uncommon entity, referre

214 These results expand our understanding of the versatility and flexibil

215 Our results expand the understanding of the functions that the wides

216 resentation and severity of ciliopathies and expand the understanding of the interactions between cil

217 The results of this study might expand the understanding of the pathogenesis of AMD and

218 novel targets of LuxR in V. harveyi and thus expand the understanding of the quorum-sensing regulon.

219 These findings expand the understanding of the role played by p300 in p

220 The expanded molecular understanding of the basis of this di

221 izing dynamic cellular activity have greatly expanded our understanding of the brain.

222 In concert, these studies have appreciably expanded our understanding of the composition and dynami

223 and SNP associations with human disease have expanded our understanding of the contribution of IFN-la

224 tial portions of the protein and has further expanded our understanding of the contribution of the po

225 eview will describe how recent findings have expanded our understanding of the development, organizat

226 iptomics, proteomics, and metabolomics, have expanded our understanding of the first signals between

227 agonists within the HEV ORF1 polyprotein and expanded our understanding of the functions of several o

228 to opportunistic mycoses have significantly expanded our understanding of the innate and adaptive im

229 f human-relevant animal models have markedly expanded our understanding of the key pathogen-host inte

230 ins bound to their ligands has significantly expanded our understanding of the macromolecular topolog

231 he last several years, we have significantly expanded our understanding of the mechanisms and pathway

232 Recent findings have not only expanded our understanding of the mechanisms controlling

233 into the pathogenesis of achondroplasia has expanded our understanding of the mechanisms of FGFR3-in

234 Use of cell-culture and animal models has expanded our understanding of the mechanisms underlying

235 Studying bmr mutants has considerably expanded our understanding of the molecular basis underl

236 Recently, advances have expanded our understanding of the pathophysiology and tr

237 Although metagenomic approaches have greatly expanded our understanding of the prokaryotic virosphere

238 Recent studies have greatly expanded our understanding of the regulation of cardiova

239 ve therapies for keratin-based diseases, and expanded our understanding of the remarkable properties

240 These recent advances have significantly expanded our understanding of the roles of caspases in r

241 These studies have expanded our understanding of the roles of miRNAs in EMT

242 nucleic acid hybridization-based assays has expanded our understanding of the spectrum of clinical i

243 europathology in an aging population, and we expanded our understanding of the TMEM106B haplotype tha

244 classes of long noncoding RNAs (lncRNAs) has expanded our understanding of the variety of RNA species

245 part in controlling CNS development, further expanding our understanding of the breadth and complexit

246 Expanding our understanding of the burden AKI has on the

247 ic-mediated oxidative stress and cell death, expanding our understanding of the common mechanism of k

248 ter structure and modulation by lipids, thus expanding our understanding of the mechanism and regulat

249 Recent research is dramatically expanding our understanding of the mechanisms by which o

250 l H2O2 concentrations, and stomatal closure, expanding our understanding of the mechanisms governing

251 cell pool in the developing cerebral cortex, expanding our understanding of the mechanisms that regul

252 potential new targets for cancer therapy and expanding our understanding of the p53 regulatory networ

253 in and kidney development in MKS, as well as expanding our understanding of the role of Mks1 in multi

254 context the evolving hypotheses that are now expanding our understanding of the roles eosinophils lik

255 overall chemistry of the catalyzed reaction, expands our understanding of the biochemistry of isomeri

256 f lipin1 in skeletal muscle regeneration and expands our understanding of the cellular and molecular

257 m for studying miRNA-HuR interactions, which expands our understanding of the combinatorial post-tran

258 The elucidation of this evolutionary path expands our understanding of the course of miRNA evoluti

259 This analysis expands our understanding of the covariation of UV-B irr

260 The SOMAmer.IL-6 structure also expands our understanding of the diverse structural moti

261 potential of uORFs in regulating translation expands our understanding of the dynamic regulation of g

262 entification of these pathways significantly expands our understanding of the genetic basis of axonal

263 eoglycorandomization of a synthetic drug and expands our understanding of the impact of sugar structu

264 This study expands our understanding of the in vivo developmental r

265 inates different binding partners, and thus, expands our understanding of the mechanisms of gene regu

266 me and lysine acetylome in SK-N-AS cells and expands our understanding of the mechanisms of perifosin

267 critical role in DBC signal transduction and expands our understanding of the mechanisms that mediate

268 This work expands our understanding of the molecular basis of fibr

269 rther analysis of some of these interactions expands our understanding of the multifunctional reperto

270 This p53-QKI-miR-20a-TGFbeta pathway expands our understanding of the p53 tumor suppression n

271 at has been accomplished in the field, which expands our understanding of the relationship between va

272 This knowledge expands our understanding of the role played by NKT cell

273 This work expands our understanding of the role played by RidA in

274 This study expands our understanding of the sequences controlling I

275 This work expands our understanding of the structure-function rela

276 ator of NK cell development and function and expands our understanding of the therapeutically importa

277 This work expands our understanding of the topology of allosteric

278 This resource expands our understanding of the unique biology of large

279 marine versus terrestrial subsurface, often expands the understanding of the genetic potential of ta

280 Investigation of rhesus miRNAs will also expand our understanding of their biological function th

281 tissue buried by ice for 400 y significantly expands our understanding of their role in recolonizatio

282 Advances in this field continue to expand our understanding of these disorders and provide

283 arine and freshwater environments that could expand our understanding of these geologically informati

284 and high resolution microscopy have begun to expand our understanding of these spatial relationships.

285 Model organisms will expand the understanding of these mutations' impact on g

286 Recent advances have greatly expanded our understanding of these receptors as complex

287 this issue of Immunity, Rauch et al. (2017) expand our understanding of this cell-intrinsic response

288 ave previously been identified, we sought to expand our understanding of this type of regulation.

289 To expand the understanding of this process, we have solved

290 Recent studies have expanded our understanding of this entity in the era of

291 hnology, and in the process are dramatically expanding our understanding of this disease.

292 In addition to expanding our understanding of this potential source of

293 This work further expands our understanding of this complex multifaceted t

294 As both clinical and basic science research expands our understanding of TIC, trauma patient care is

295 ent cell types and disease states is rapidly expanding, our understanding of transcript function lags

296 dependent on various myeloid cell types has expanded our understanding of tumor angiogenesis and has

297 The field of viral metagenomics has expanded our understanding of viral diversity from all t

298 These studies will likely expand our understanding of virus ecology and evolution.

299 ory network of primary ARL tumor samples and expand our understanding of virus-associated oncogenesis

300 ical examination of these interactions could expand our understanding of viruses and be exploited for