ライフサイエンスコーパス: expansion

1 control of alloreactive T cell apoptosis and expansion.

2 ntigens did not display preferential in vivo expansion.

3 a growth advantage to tumor cells for clonal expansion.

4 h may give rise to disease-associated repeat expansion.

5 n ylide formation followed by azetidine ring expansion.

6 forces within cell colonies, enabling their expansion.

7 ic mixture on the velocity of invasive range expansion.

8 the most effective in reducing leukemic cell expansion.

9 ly drive and specify the extent of stem-cell expansion.

10 able colours, with the potential for further expansion.

11 ification of a material undergoing anomalous expansion.

12 se in global soil erosion driven by cropland expansion.

13 he collapsed phase shows nearly zero thermal expansion.

14 y a more precise, second-order Taylor series expansion.

15 obstruction, most likely because of stromal expansion.

16 the extracellular acidification and cellular expansion.

17 DR demethylated phenotype following in vitro expansion.

18 Nivolumab 3 mg/kg was chosen for dose expansion.

19 coding sequence evolved through a CAG repeat expansion.

20 the ECM to both "healthy" and "unhealthy" AT expansion.

21 ted with the degree of evolutionary cortical expansion.

22 ming a proposed mechanism for triplet repeat expansion.

23 and are unstable at the time scales of cell expansion.

24 must therefore be modified to allow cellular expansion.

25 this molecule as a trigger for CD4(+) T cell expansion.

26 x, indicating that MutSbeta abundance drives expansions.

27 variance in speed among replicate population expansions.

28 maining three samples identified as possible expansions.

29 H1 and 2HG are not required for later clonal expansions.

30 014 and 2015) relative to the 4 years before expansion (2010 through 2013) in states with and without

31 2 years after implementation of the Medicaid expansion (2014 and 2015) relative to the 4 years before

32 enhancement have increased rates of aneurysm expansion (3.1+/-2.5 versus 2.5+/-2.4 mm/year, P=0.0424)

33 Msh3 overexpression led to high expansion activity and elevated levels of MutSbeta compl

34 limit by compensating the intrinsic thermal expansion, allowing a sub-25 Hz linewidth and a 32 Hz Al

35 ver that whereas cell divisions drive tissue expansion along one axis, their contribution to expansio

36 ansion along one axis, their contribution to expansion along the orthogonal axis is cancelled by cell

37 Genetic code expansion and bioorthogonal labeling provide for the fir

38 and may reflect the differing dependence of expansion and biosynthesis on energy, carbon, and water.

39 ey transcription factors responsible for the expansion and differentiation of human IL-10-producing B

40 o orthodontic treatment with rapid maxillary expansion and facemask therapy.

41 bRG and BG have been implicated in the expansion and folding of the cerebrum and cerebellum, re

42 cessing is a critical mechanism for proteome expansion and gene regulation in higher eukaryotes.

43 e found that Runx3 deficiency limited clonal expansion and impaired upregulation of cytotoxic molecul

44 focused on their harvesting pre-transplant, expansion and infusion post-transplantation.

45 rds initial fusion-pore opening, hinders its expansion and leads to premature closure in most instanc

46 to be safe and effective in reducing tumour expansion and lengthening the survival of intracranially

47 interaction pathway, which can promote their expansion and migration.

48 However, ex vivo expansion and pharmacological/genetic modification of hu

49 antage to mutant cells, driving their clonal expansion and potentially leading to leukemia.

50 le of natural enemies across the initiation, expansion and recovery stages of a natural ecosystem's c

51 amplification of IDH1 was followed by clonal expansion and recurrence at a higher grade.

52 lar ultrasound on the main vessel (MV) stent expansion and SB fractional flow reserve (FFR) in patien

53 esting extensive and serial rounds of clonal expansion and selection.

54 of the hundreds of mitonuc genes, but range expansion and species replacement likely promoted massiv

55 ore rim marks the progress of both organelle expansion and ultimately organelle closure around a part

56 10 increase, (ii) CD73(+)Foxp3(+)Treg subset expansion, and (iii) specific correlations between gene

57 e cumulus cells, much increased cumulus cell expansion, and an accelerated severance of cytoplasmic p

58 nd tooth-forming capacity following in vitro expansion, and at ratios >1:3 postnatal:embryonic cells,

59 B-cell responses result in clonal expansion, and can occur in a variety of tissues.

60 um to optimize approaches for the isolation, expansion, and differentiation of appropriate kidney cel

61 hus, CysLT2R signaling, IL-33-dependent ILC2 expansion, and IL-33-driven mast cell activation are nec

62 F3 also developed lung disease, myeloid cell expansion, and T cell cytopenia.

63 ius development was derived by an asymptotic expansion approach.

64 y that RBK1 effects on auxin-responsive cell expansion are mediated through phosphorylation-dependent

65 erials in which the skyrmion compression and expansion are reversible.

66 if the rates of marine ecosystem decline and expansion are similar and low; (2) marine protection sho

67 Longer repeat expansions are associated with genetic anticipation (ie,

68 F families tend to contain more genes; these expansions are linked to adaptation to environmental str

69 response and esophageal toxicity, esophageal expansion, as a method to quantify radiosensitivity in 1

70 ys hypersensitivity in auxin-responsive cell expansion assays.

71 tensive BP lowering on significant haematoma expansion at 24 hours warrants further investigation.

72 support tissues, and for restricting auricle expansion at the midrib.

73 Phase 1 study with dose escalation and dose expansion at the University of Texas MD Anderson Cancer

74 end scenarios for the extent of agricultural expansion before 1850 CE are not compatible with the C b

75 eustatic changes influenced the demographic expansion but not population structure in AF biota.

76 pation in families carrying a C9orf72 repeat expansion by means of a decrease in age at onset across

77 al surface cells not only trigger blastoderm expansion by reducing tissue surface tension, but also d

78 ules can induce 100-fold volumetric hydrogel expansion by successive extension of cross-links.

79 amma in a Tbet independent manner, and whose expansion can be enhanced by IL4.

80 ementia, though the mechanisms by which such expansions cause neurodegeneration are poorly understood

81 nge of evolutionary processes such as genome expansion, chromosomal rearrangement, and chromosomal tr

82 PPC revealed that the volume expansion coefficient of DMPC and DMPC/Cholesterol sampl

83 Patients in the expansion cohort were treated with 1.0 mg/kg luspatercep

84 he main cohort, and 12 months (8-15) for the expansion cohort.

85 c samples from two selected disease-specific expansion cohorts at the same study site who had serum s

86 Expansion cohorts were initiated at 3.0 mg/kg in patient

87 We show that gene expansion contributes to the evolution of the IFN system

88 then used to query the "metabolic in-silico expansion" database (MINE DB) to obtain possible molecul

89 nteraction between gender and C9orf72 repeat expansions demonstrated that the reduced survival due to

90 s, amyotrophic lateral sclerosis, nucleotide expansion disorders (Friedreich ataxia and fragile X syn

91 The presence of the C9orf72 repeat expansion does not fully account for this finding, sugge

92 lar subdomain within the midhypocotyl, whose expansion drives the final step of this developmental tr

93 n unprecedented early and northward spawning expansion during 2015-16.

94 pulation diversity and clonal viral sequence expansion during CD4+ T-cell reconstitution following ch

95 T1D subjects, consistent with in vivo T cell expansion during disease progression.

96 tor nuclear factor I-A (NFI-A) controls MDSC expansion during sepsis and impacts survival.

97 usually takes >6 months and results in a CTC expansion efficiency of <20%.

98 ok and Pkn is important for unequal cortical expansion, ensuring correct cleavage furrow positioning

99 uiescent human hematopoietic stem cell (HSC) expansion ex vivo have been identified; however, the mol

100 ESF expansion (from 0% to 100%) was associated with a 15.4%

101 t that LDD events specifically targeting the expansion front are most efficient in suppressing introg

102 The southern and more recent expansion front occurred approximately 40 years later an

103 ntact zone between these two distinct coyote expansion fronts.

104 gnaling to the diurnal regulation of rosette expansion growth and leaf movement in Arabidopsis (Arabi

105 ued, revealing that the clock also regulates expansion growth more directly.

106 Across eight major pollutants, the program expansion had virtually no discernible effect on polluti

107 Range expansion has genetic consequences expected to result in

108 Clonal expansions have differentiated from a naive to effector

109 aemolytic anaemia, compensatory haemopoietic expansion, hypercoagulability, and increased intestinal

110 1/2 inhibitor treatment up-regulated B1 cell expansion, IgM production, phagocytic receptor expressio

111 ich help lower the energetic barrier to pore expansion.IMPORTANCE Influenza A virus is an airborne pa

112 l, there is little evidence that the program expansion improved air quality.

113 t the KDM5s are necessary for mitotic clonal expansion in 3T3-L1 cells, indicating that KDM5 KD may i

114 in transplant and alloantigen-induced T cell expansion in draining lymph node experiments.

115 we tested for differentiation, movement and expansion in four elevational generalist songbird specie

116 transcription, the past 5 years has seen an expansion in knowledge of new cellular regulators and ro

117 red to be the main driver of serotype IV GBS expansion in North America.

118 ethod is demonstrated to control the thermal expansion in open-framework materials by adjusting the p

119 n-echolocating fruit bats showed evidence of expansion in ORs, supporting a "trade-off" between senso

120 A hexanucleotide repeat expansion in the C9orf72 gene is the most common cause o

121 Polyglutamine (polyQ) repeat expansion in the deubiquitinase ataxin-3 causes neurodeg

122 ntington's disease is caused by a CAG repeat expansion in the huntingtin gene, HTT.

123 enerative disorder caused by a polyglutamine expansion in the N-terminal region of the huntingtin pro

124 considered to remain resistant to such shrub expansion in the next decades.

125 orates with FLT3-ITD to promote myeloid cell expansion in vivo and that this involves a multitarget m

126 bution or the underlying mechanism of clonal expansion in vivo.

127 ly, Giardia colonization is typified by both expansions in aerobic Proteobacteria and decreases in an

128 e and applicability of ongoing natural range expansions in the context of climate change to gain esse

129 hat pheromone perception in ants evolved via expansions in the numbers of odorant receptors (ORs) and

130 orroborate several lineage-specific TLR gene expansions in urchins and cephalochordates.

131 and large-scale trinucleotide (GAA)n repeat expansions in vivo, implying failed phosphate-steering p

132 Its rapid geographic expansion is attributed to the success of Aedes mosquito

133 of approximately 20 microns have shown that expansion is constrained, suggesting that microbubble ec

134 Mitotic area expansion is largely driven by regulation of cytoplasmic

135 ular, accurate detection of pathological STR expansion is limited by the sequence read length during

136 hole or n-->sigma* model applies, any octet expansion is now seen as largely formal, however, becaus

137 verned by three essential parameters: (1) an expansion length beyond which selection dominates over g

138 Rapid climate warming has resulted in shrub expansion, mainly of erect deciduous shrubs in the Low A

139 and expanded conformations, and the level of expansion may be regulated and important for function.

140 n-specific TCM, resulting in enhanced T cell expansion measured during subsequent booster injections

141 esis by utilizing the thermal coefficient of expansion mismatch between the substrate and semiconduct

142 The two-stage clonal expansion model we propose is based on the thesis that a

143 Multistage clonal expansion (MSCE) models are a class of continuous-time M

144 ysis of healthy controls and carriers of CAG expansion mutations in HTT participating in the 3-year i

145 r via a hysteretic pathway where most of the expansion occurs in a single abrupt step.

146 ited neurodegenerative disease caused by the expansion of a CAG repeat in the HTT gene.

147 unneling reaction involving spontaneous ring expansion of a fused-ring benzazirine into a seven-membe

148 GF, they become far less so, resembling free expansion of a gas.

149 icity of Th17 cells, but rather promoted the expansion of a GM-CSF(+) Th17 cell subset, thereby enhan

150 cumulates some starch, but is obliterated by expansion of a massive endosperm, where all embryo-nouri

151 We propose that demographic range expansion of a microbial population capable of horizonta

152 onditioning, there was rapid engraftment and expansion of a polyclonal pool of transgene-positive fun

153 We studied the nanoscale thermal expansion of a suspended resistor both theoretically and

154 n sympathetic tone of the adipose tissue and expansion of activated macrophages, both of which occurr

155 Expansion of adipose tissue in response to a positive en

156 esin from recipient mice supported the rapid expansion of adoptively transferred CD8+ T cells against

157 ibition to compensatory hyperglucagonemia or expansion of alpha-cell mass, and that it cannot be give

158 In contrast, anti-CTLA-4 induces the expansion of an ICOS(+) Th1-like CD4 effector population

159 Expansion of an observation alone strategy for low-risk

160 xamples where both cyclopropanation and ring expansion of arenes were rendered reversible.

161 Expansion of ARF3 expression into lateral epidermal cell

162 The origin and expansion of biological diversity is regulated by both d

163 -bet expression by natural killer cells, and expansion of blood monocytes with less proinflammatory c

164 cal insults (infarcts), suggesting a similar expansion of cells that lack terminal glial differentiat

165 ellular clusters, which further promotes the expansion of confluent cellular layer.

166 A Bayesian skyline plot revealed the rapid expansion of CRF01_AE in China around 1999-2000.

167 DM1) is a rare genetic disease caused by the expansion of CTG trinucleotide repeats ((CTG)exp) in the

168 ysbiosis of the microbiota, characterized by expansion of Escherichia coli.

169 nized xenograft model of FSGS resulted in an expansion of Gr-1(lo) cells in the BM, leading to high p

170 gene overexpression, enhanced self-renewal, expansion of hematopoietic progenitors, and myeloid diff

171 Expansion of HIV-infected CMV/EBV-specific CD4 + T cells

172 ition, ANX - A1 (-/-) mice exhibited greater expansion of HSPCs and altered pattern of HSPC mobilisat

173 atopoietic stressors result in the selective expansion of HSPCs carrying specific gene mutations.

174 ARCH is defined as the gradual, clonal expansion of HSPCs carrying specific, disruptive, and re

175 Engraftment and/or expansion of HSPCs was dependent on the expression of en

176 t that adaptive pathways co-evolved with the expansion of IDDs in the proteome of eukaryotic cells to

177 erm IL-33 treatment in mice led to sustained expansion of IL-33 receptor-positive kidney ILC2s and am

178 A key role in controlling anisotropic expansion of individual cells is played by the cortical

179 These findings suggest that peripheral expansion of induced Treg cells can serve as a promising

180 le-knockout mice that is caused by unchecked expansion of invariant NKT (iNKT) cells or a unique subs

181 ght and temperature, and allowed substantial expansion of its distribution range.

182 lear cells elicited a cell contact-dependent expansion of MDSCs.

183 The expansion of Medicaid eligibility under the Affordable C

184 fferentiation biomarkers, reinnervation, and expansion of melanocyte and Merkel cell pool during repa

185 expanded in IL-7 and IL-15 produced greater expansion of memory stem T cells and central memory T ce

186 stage C, and was correlated with both local expansion of metabolically active bone marrow documented

187 Here, we show that Aid loss in mice leads to expansion of myeloid cells and reduced erythroid progeni

188 ad extensive lymphocytosis marked by massive expansion of natural killer (NK) and T cell compartments

189 tis-associated cancer (CAC) and inhibits the expansion of neutrophils and granulocytic myeloid-derive

190 iche modeling suggested that a gradual range expansion of P. hwangshanensis during the Pleistocene cl

191 permafrost peat plateaus ('forest') lead to expansion of permafrost-free wetlands ('wetland').

192 poral difference, our data indicate that the expansion of PP2A subunit gene families in both flowerin

193 t of diversity could be remedied by a slight expansion of protected areas: an additional 5% of the la

194 Expansion of PSGL-1(lo)CD4(+) T cells is also prevented

195 omplex natural products now exists such that expansion of scope seems inevitable.

196 sence of H-2L(d)/AH1-specific T cells and an expansion of sequence diversity in treated mice.

197 e evolution of sexual dimorphism and genomic expansion of sex chromosomes.

198 The control of thermal expansion of solid compounds is intriguing but remains c

199 The unstable expansion of some STRs was associated with various genet

200 olic disease in obesity whereas preferential expansion of subcutaneous white adipose tissue (WAT) app

201 nges in intratumoral TCR repertoire revealed expansion of T cell clones in the setting of neoantigen

202 Trauma-induced expansion of Th17-type CD4 T cells was seen with increas

203 V infection, restoration is mainly due to an expansion of the "exhausted," virus-specific B cells, i.

204 y, we do not observe the extreme copy number expansion of the AMY2B gene characteristic of modern dog

205 circulating tissue-like memory B cells, and expansion of the B regulatory cells (Bregs).

206 Our work opens a venue for the expansion of the classification of topological phases of

207 ondensation temperature appear to affect the expansion of the cloud, as if the system has turned into

208 The continued expansion of the fields of macromolecular chemistry and

209 Gene-specific expansion of the genetic code allows for UGA codons to s

210 ylomes, we uncovered an overall evolutionary expansion of the hypomethylated fraction of the genome,

211 The quest towards expansion of the M n+1AX n design space has been acceler

212 These mice concomitantly exhibit an expansion of the mammary epithelial stem cell (MaSC) enr

213 way, the alkylidene ligand is lost, via ring expansion of the metallacyclobutane intermediate, leadin

214 crophages within lesions and controlling the expansion of the necrotic core by impairing efferocytosi

215 However, considering the tremendous overall expansion of the neocortex in human evolution, it has pr

216 show that sexual selection leads to greater expansion of the non-recombining region and increased Y

217 nation, we observed an approximately 70-fold expansion of the plasmablast population.

218 HIV reservoir is slowed over time in part by expansion of the pool of HIV-infected cells.

219 ctors in the tubovesicular network (TVN), an expansion of the PVM into the host cytoplasm.

220 uence analysis, new visualization tools, and expansion of the RGI for detection of emergent AMR threa

221 The expansion of the role of dermatology consultation servic

222 sease flares were associated with the clonal expansion of the S. aureus population, occurring over a

223 groups, additional efforts culminated in the expansion of the scope of the substitution to various he

224 n-phosphorylatable AGO2 reveals a pronounced expansion of the target repertoire bound at steady-state

225 management and established a foundation for expansion of the theranostic principle into other oncolo

226 ization of M2 macrophages, thereby enhancing expansion of the Treg cell population via IL-10.

227 alloreactive CD4(+) T cells, increasing the expansion of this population and its CD40 expression, wh

228 Further expansion of this study will provide more insight into t

229 ity of large numbers of cells, in vitro cell expansion of tooth-inducing cell populations is an essen

230 Over the next 35 years, the expansion of treatment will avert an additional 3.8 mill

231 The rapid expansion of unconventional oil and gas development has

232 We find a simultaneous expansion of wetland area, driven by the excess precipit

233 The circumpolar expansion of woody deciduous shrubs in arctic tundra alt

234 as in no case paralleled by the emergence or expansion of X4-tropic provirus variants.

235 virus (CMV) infection sometimes causes large expansions of CMV-specific T cells, particularly in olde

236 pathogenicity is associated with remarkable expansions of protease and cell wall gene families, whil

237 Expansions of short nucleotide repeats produce several n

238 Identifying large expansions of short tandem repeats (STRs), such as those

239 hitin accumulation in hyphal tips and lesion expansion on wounded hosts, but significantly promoted g

240 ny phase was related to substantial hematoma expansion (P < .001 for all comparisons; Bonferroni adju

241 reater the frequency of substantial hematoma expansion (P = .013).

242 atation (P=0.002) but achieved greater stent expansion (P<0.001) and less incomplete stent apposition

243 art of a two-part study with the second dose-expansion part ongoing and enrolling patients as of July

244 Before the 2006 Massachusetts insurance expansion, patients with government-subsidized or self-p

245 s treated with nivolumab 3 mg/kg in the dose-expansion phase and 15% (95% CI 6-28) in the dose-escala

246 denib 100 mg once daily was selected for the expansion phase on the basis of pharmacokinetic and phar

247 se-escalation phase and 20 (53%) in the dose-expansion phase were still receiving treatment.

248 In the dose-expansion phase, AZD3759 at 200 mg or 300 mg twice a day

249 In the dose-expansion phase, patients were treated with selinexor at

250 riteria In Solid Tumors version 1.1) for the expansion phase.

251 Results The dose-escalation and expansion phases enrolled 26 and 25 patients, respective

252 Adipose tissue expansion progresses rapidly during postnatal life, infl

253 e-1 ST-segment elevation correlated with AES expansion (r=0.682, P<0.001).

254 arenes in thermally reversible Buchner ring expansion reactions, marking the first examples where bo

255 action to persistent antigen; yet, excessive expansion reduces memory potential and impairs antitumor

256 andscape-scale patterns and drivers of shrub expansion remain poorly understood, inhibiting accurate

257 Hexanucleotide repeat expansions represent the most common genetic cause of am

258 We further found significant expansion, retention, and class-switching of autoreactiv

259 vide, which is consistent with the two known expansion routes.

260 e coverage are limited and, in practice, the expansion scenarios considered may exceed feasible level

261 mal RNA (rRNA) adjacent to the c loop of the expansion segment 7 (ES7), a putative regulatory region

262 le in membrane fusion and contribute to cell expansion, signaling, and polar growth in plants.

263 We studied the association between CTG expansion size and other baseline characteristics and (1

264 Adaptive immunity is driven by the expansion, somatic hypermutation, and selection of B cel

265 uld also play a critical role in determining expansion speed but controlled experiments are lacking.

266 an immediate role, governing the growth and expansion speed of colonizing populations.

267 argest in low-income patients who resided in expansion states (9.6% to 3.6%; APC, -6.0%; 95% CI, -6.5

268 ng low-income people who resided in Medicaid expansion states.

269 article in 2014, including specific areas of expansion such as common (complex) disease, new algorith

270 normal levels showed no detectable change in expansions, suggesting these polymorphisms primarily aff

271 The mode expansion theory is developed to help understand how the

272 e optimal when the ratio of marine ecosystem expansion to decline is greater than 1:1.4, with terrest

273 There is little room for cropland expansion to increase production but redistribution of c

274 community-specific quality initiatives, and expansion to other operations are warranted.

275 e mining infrastructure establishment, urban expansion to support a growing workforce, and developmen

276 Herein we report a significant expansion to the scope of substitution reactions for the

277 osition, but that DNA loss counteracted this expansion to various extents across lineages.

278 ents of alkynes by coupling homoallylic ring expansion to yield the formal "6-endo" products with aro

279 mg/kg, and 20 mg/kg), with dose-level cohort expansions to provide additional safety, pharmacokinetic

280 Most droplet expansion took several hours and occurred in apical nucl

281 Here we exploit the huge volumetric expansion (up to 3000%) of a new type of building block,

282 010 through 2013) in states with and without expansions, using data from the National Health Intervie

283 olecular machine function of contraction and expansion utilizing the binding features of CyP6Q[6] and

284 xpression in T cells, and CD70 limits T cell expansion via a regulatory T cell-independent mechanism

285 Medicaid expansion was associated with increased insurance covera

286 ted that the reduced survival due to C9orf72 expansion was being driven by spinal onset males (HR 1.5

287 d Belgian families in which a C9orf72 repeat expansion was segregating.

288 tlenecks and allele surfing during northward expansion, we document a northern-most population with l

289 omas hold the "genomic recipe" for beta cell expansion, we surveyed 38 human insulinomas to obtain in

290 Expansions were not associated with significant changes

291 and 24 mo), posttransplant NKG2C(+) NK cell expansions were not observed in every patient with detec

292 able TSDR demethylated FOXP3 phenotype after expansion whereas CD4CD127CD25CD45RA Treg cell lost the

293 the gene resulting in polyglutamine (polyQ) expansion which has been assumed to result in gain of fu

294 is excluded from the population during range expansions (which acknowledges a classical prediction).

295 increased fluid flow that triggers lymphatic expansion, which is conceptually similar to hypoxia-trig

296 Characterizing the association of Medicaid expansion with hospitalization after injury is vital in

297 heir biotransformation products, through its expansion with over 700 000 chemical structures to now i

298 gn to predict intracerebral hemorrhage (ICH) expansion with standardized multiphase computed tomograp

299 reg had a greater capacity to suppress after expansion with TAC.

300 mammary luminal cells leads to their clonal expansion without directly affecting their luminal ident