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1 intervention (greater effectiveness and less expensive).
2 suitable for campaign use than OPV, and more expensive.
3 rapeutic cell-based products are complex and expensive.
4  consuming, but they are also cumbersome and expensive.
5 plex, difficult to interpret, and relatively expensive.
6  mass spectrometer (MS) can be extensive and expensive.
7  workshop content is both time-consuming and expensive.
8 d on pupil functions, can be computationally expensive.
9  the prephasing task becomes computationally expensive.
10 g methods that are slow, labor-intensive and expensive.
11 es, while NB-fit is the most computationally expensive.
12  usually time-consuming, labor-intensive and expensive.
13 hat are unproven in practice and may be more expensive.
14 ssociation studies can be time-consuming and expensive.
15  new medicines is difficult and increasingly expensive.
16 ntional serotyping methods are laborious and expensive.
17                 However, such a diet is more expensive.
18 s in the scoring function is computationally expensive.
19  although ultimately effective, was slow and expensive.
20 sion applications, which are computationally expensive.
21 n of such vast amounts of sequencing data is expensive.
22 sadvantages, ELISA can be time-consuming and expensive.
23 ction techniques tend to be laborious and/or expensive.
24  are technically demanding, inefficient, and expensive.
25 quire high coverage by long reads and remain expensive.
26    However, producing wings is energetically expensive.
27 ted counterparts are either not available or expensive.
28 antagonists) have increased efficacy but are expensive.
29 linical trials, but it is time-consuming and expensive.
30 extracting these features is computationally expensive.
31 ecution of such advice can be cumbersome and expensive.
32 cess is labor-intensive, time-consuming, and expensive.
33 ynthesis methods are typically elaborate and expensive.
34  used to create cytoreagents are complex and expensive.
35 s for Alzheimer disease (AD) are invasive or expensive.
36 ocedures performed in the West were the most expensive ($28289), with a greater odds of increased exp
37 lity of NGS and are concerned it could be an expensive addition to cancer diagnostics, rather than an
38 l audits appear to be a viable and much less expensive alternative to in-person audits for assessing
39 ebrospinal fluid samples can serve as a less expensive, alternative diagnostic strategy in developing
40  these studies to large imaging datasets and expensive analysis workflows.
41 cally require laborious, time-consuming, and expensive analytical workflows.
42  of prefunctionalization in addition to less expensive and abundant metal catalysts.
43              However, all of these drugs are expensive and are not available or affordable in all cou
44    Food commodities and ingredients that are expensive and are part of complex supply chains are part
45 systems for ELISA incubation and reading are expensive and bulky, thus cannot be used at point-of-car
46                         HABP/VABP trials are expensive and challenging to conduct due to protocol com
47 r the diagnosis of DENV in humans or are too expensive and complex for sustainable monitoring.
48 bricated from rigid materials is confined to expensive and complex methods.
49 vitamin K antagonist oral anticoagulants are expensive and contraindicated for several conditions.
50 ectrodes generated responses similar to more expensive and difficult to fabricate graphene and highly
51 l carbothermic reduction process required is expensive and energy-intensive; in this work, we use an
52                               It can replace expensive and error-prone manual parsing and standardiza
53 ecies can be carried out but they may become expensive and ethically questionable.
54          Current technological solutions are expensive and focused on treating ARD on release rather
55 tiation were necessary when medications were expensive and had severe side effects, and when the impa
56 y diagnostic tests for urothelial cancer are expensive and have limited sensitivity and specificity.
57 ointestinal pathogens are time-consuming and expensive and have limited sensitivity.
58                     To circumvent the use of expensive and inefficient Pt catalysts, multicopper oxid
59 nt potential to replace the reliance on more expensive and laborious PCR assays.
60        Traditional Ab formats (IgG, IgM) are expensive and laborious to produce; however, the introdu
61 d to test out essential proteins are usually expensive and laborious, computational methods, which ut
62        Early posttransplant malignancy is an expensive and morbid condition that warrants attention i
63 e through the High Risk Clinic was both less expensive and more effective than standard care.
64  (QqQ) instruments, which are typically less expensive and more robust than other types of mass spect
65  However, nitrogen fertilizer application is expensive and negatively affects the environment, and su
66  animal models of S. aureus colonisation are expensive and normally require antibiotics.
67 o manage many diseases and conditions but is expensive and not always efficient.
68 antibody conjugates is often complicated and expensive and not commonplace in academic laboratories.
69 esses that usually require organic solvents, expensive and often dangerous coupling reagents, and mas
70             However, most of the methods are expensive and often present environmental challenges.
71  the use of cadaveric biologic mesh has been expensive and plagued by complications such as seroma, i
72 ients with intravenous iron products is both expensive and poses logistical challenges for outpatient
73 make a definitive diagnosis; these are often expensive and potentially associated with severe reactio
74 e rapid development of modern, powerful, but expensive and potentially toxic treatments.
75 peptide (GLP)-1 receptor agonists, which are expensive and require daily injections that may result i
76            However, such tools are generally expensive and require expertise to handle.
77 me hospitals, as they are time-consuming and expensive and require hospital staff to be performed.
78        Other nucleic acid-based methods were expensive and required trained personnel.
79                              This process is expensive and requires special equipment, experienced pe
80 ty measurement techniques, both of which are expensive and sophisticated.
81 cement and substrate reduction therapies are expensive and still associated with inflammation, increa
82 le who inject drugs (PWID), but treatment is expensive and TasP's effectiveness is uncertain.
83 , since protein translation is energetically expensive and tightly controlled, it is unclear if highl
84 ds used to identify DNA-binding proteins are expensive and time consuming and thus attracted research
85                               However, it is expensive and time consuming based only on experimental
86                                  Cumbersome, expensive and time consuming detection techniques presen
87 es for measuring chromatin accessibility are expensive and time consuming, appealing for the developm
88 ns by electron or fluorescence microscopy is expensive and time consuming.
89            Specimen submission would be less expensive and time-consuming for clinical laboratories;
90 elopment and application is still limited by expensive and time-consuming process development and pro
91     However, the best model organisms remain expensive and time-consuming to use.
92 ssociations between lncRNAs and diseases are expensive and time-consuming.
93 oring of hydrocarbon (HC) pollution is often expensive and time-consuming.
94 al prediction of drug-target interactions is expensive and time-consuming.
95 ic parts controlling each gene, which can be expensive and time-consuming.
96  with treatment," and that treatment was too expensive and too complicated to deliver.
97 induced borylation protocol does not require expensive and toxic metal catalysts or ligands, and it p
98 stomary use of iodoarenes, which can be both expensive and toxic.
99  would be 6.1% more sensitive and 17.7% less expensive and would have a significantly lower average f
100                    Current AD biomarkers are expensive and/or invasive and therefore unsuitable for u
101  However, human recombinant cystatin is very expensive, and alternatives to its use are necessary.
102  Monte Carlo simulations are computationally expensive, and are therefore not suitable for large-scal
103 -aperture objective lenses, which are bulky, expensive, and difficult to miniaturize.
104 ess and endoscopic surveillance is invasive, expensive, and fraught by issues of sampling bias and th
105 fication of organisms can be time consuming, expensive, and invasive.
106 t are broader spectrum, more toxic, and more expensive, and mortality attributable to antibiotic-resi
107  long and variable humanization process, are expensive, and require the use of breeding-challenged mo
108 astatic disease, which is often challenging, expensive, and risky to biopsy.
109 ulture screening, which is laboratory-based, expensive, and time-consuming.
110 i) is faster, less labor intensive, and less expensive; and (iv) can be readily adapted into a high-t
111 nes, glycopeptides, cephalosporins and other expensive antibiotics resulting in significantly higher
112 fic peptide aptamers can be used in place of expensive antibody proteins, and they are gaining increa
113             Limiting out-of-pocket costs for expensive anticancer drugs like the IMiDs may improve ac
114  Wisely (CW) campaign discouraged overuse of expensive antiemetics in patients with low risk of chemo
115 tion, but these require customized hardware, expensive apparatus, and advanced informatics or can onl
116 -oral interferon-free regimens were the less expensive approach: PPP$ 19,761.72 (US$ 10,985.90) for S
117 y used ELISA to more sophisticated, and more expensive, approaches such as digital ELISA.
118 h has proven to be too slow, unreliable, and expensive as conducted in the past.
119                                        While expensive avalanche photodiodes and superconducting bolo
120        Exposure did not elicit energetically expensive behaviors, but scallops showed significant cha
121  able so far to induce bnAbs demanding their expensive biotechnological production.
122 ds the issue of how the large, metabolically expensive brains of Homo sapiens can be energetically af
123 d evolutionary methods, which are often less expensive, can be broadly relevant for understanding eco
124 sk for financial hardship given increasingly expensive cancer care and significant cost sharing by be
125 most common in incidence and one of the most expensive cancers to treat.
126 ic elements such as chromium or selenium) or expensive catalysts (such as palladium or rhodium).
127 m the realization of more efficient and less expensive catalysts compared with noble metal catalysts,
128 cient (the sickest proteins use the most ATP-expensive chaperones), comprehensive (it can handle any
129 ophisticated time-lapse microscopy, or bulky/expensive chemo-stat instrumentation for dynamic measure
130 s the development of a next generation, less expensive, cleaner process that can allow the vast reser
131 or investment in designing high-capacity but expensive CO2 sorbent for developing practical or cost-e
132            One reason is the prerequisite of expensive cofactors.
133 spital and specialist settings, towards less expensive community-based models.
134  inverse method based explanations, avoiding expensive computation of the inverse kinematics and the
135 ng precomputed data, the often prohibitively expensive computations associated with high accuracy sim
136  is a leading cause of death and is the most expensive condition to treat in U.S. hospitals.
137 have excluded about 70% of all newborns from expensive confirmatory testing by IEF, without missing a
138  with those determined by more laborious and expensive conventional methods.
139 olution data than are currently supported by expensive conventional sampling methods.
140 hanism well-suited to suppress energetically expensive correlated network events under conditions of
141 owever, manual analysis can be prohibitively expensive, creating a bottleneck between collected image
142 leropages formosus), one of the world's most expensive cultivated ornamental fishes, is an endangered
143 at 3 to 4 months comparable to those of more expensive custom-made spectacles among eligible school-a
144 o those acquired with a much larger and more expensive desktop DFMM system.
145  based on either human visual observation or expensive detectors, which are costly for future pervasi
146 ions for nanoparticle quantification rely on expensive DFM systems.
147 tential for more sensitive, fast and/or less expensive diagnostic assays for dengue.
148 (-)-enantiomer of the scarcely available and expensive diamine sparteine; also, these building blocks
149 e is ideal; and this conventionally requires expensive "die upset" processing routes.
150 omplex samples was achieved by a simple, non-expensive, eco-friendly and robust system.
151  further development of more active and less expensive electrocatalysts are provided.
152 tate and reducing the need for energetically expensive electron donor molecules.
153 ve surfaces and optimized utilization of the expensive element, Pt.
154 are rapid, highly sensitive, selective, less expensive, environmentally friendly, and easy to handle.
155 d in these methods including time-consuming, expensive equipment and high consumption of reagents, ne
156 , nowadays only allowed by sophisticated and expensive equipment and laborious methods.
157                   Ocular fundoscopy requires expensive equipment and technical expertise not often av
158 r determining HMF are cumbersome and require expensive equipment or hazardous reagents.
159                         However, it requires expensive equipment, and hepatogastroenterologists are g
160 fact that these methods require specific and expensive equipments.
161 550 vs $29,738; P < 0.001), and $19,147 more expensive for colectomy ($51,893 vs $32,746; P < 0.001).
162 ly, which is error-prone and computationally expensive for complex data.
163 de in the past decade, DNA synthesis remains expensive for many applications.
164 ($45,570 vs $31,426; P < 0.001), $9,812 more expensive for pulmonary resection ($39,550 vs $29,738; P
165 ither limited resolution (CMA) or are highly expensive for routine screening (both CMA and WGS).
166 PCR), however, the hardware is prohibitively expensive for widespread utility.
167      B. pertussis also requires a relatively expensive growth medium.
168       Currently, the study of cilia requires expensive high speed cameras and high powered microscope
169 an 200 kPa, which eliminated the need for an expensive high-pressure pump and chromatography system.
170  was that patient care would shift away from expensive hospital and specialist settings, towards less
171     Topologically efficient and biologically expensive hubs of the brain anatomical network had great
172 nes/strategies before they proceed to large, expensive human trials.
173 sis remains one of the most debilitating and expensive illnesses, and its prevalence is not declining
174 can be life-saving, but can be prohibitively expensive in low-income settings.
175                       Surgical care was more expensive in these patients (mean [SD] cost, MP $8970 [M
176 igators typically rely on time-consuming and expensive in-person systematic neighborhood audits.
177 n be performed in situ, without the need for expensive infrastructure or amendments.
178 ction techniques are time-consuming, require expensive instrumentation and are labour-intensive.
179  such as easy-to-manufacture, do not require expensive instrumentation, and allow creation of lower m
180 ny materials but has required very large and expensive instrumentation.
181 tion is limited due to longer analysis time, expensive instruments and expertise needed for operation
182 ous and time-consuming sample treatments and expensive instruments.
183           This diagnosis in turn can lead to expensive, invasive, and even harmful surveillance and t
184 uding poor performance, short-lifetimes, and expensive ion-selective membranes as well as high price,
185 The Y2Ru2O7-delta pyrochlore is also free of expensive iridium metal and thus is a cost-effective can
186 sible; for that reason, a new chip (which is expensive) is required for every successful or futile at
187 encing, which are typically slow and require expensive lab-based equipment.
188 e ease of multiplexing, without the need for expensive labelling methods or extensive sample pre-trea
189 m processing rely on the use of specific and expensive labels (e.g. FACS or MACS).
190       However, the existing technologies are expensive, labor intensive and time consuming, posing si
191 put assays to detect these modifications are expensive, labor-intensive, unfeasible in some contexts
192 o that reported for the introduction of new, expensive laboratory tests, and therefore warrant furthe
193 olated precedents requiring specialized, yet expensive, ligands, high temperatures, and pi-extended b
194 d surface reflection (DFSR) are advanced but expensive light microscopy techniques with limited avail
195 d whilst powerful, these are computationally expensive, limiting practicality.
196                   It is also computationally expensive, limiting the ability to conduct comprehensive
197 binding materials is both time-consuming and expensive, limiting the use of this technique to small s
198 339 (US$449) per patient, the panel was less expensive locally than performing more than two or three
199  is similar to those obtained using the more expensive long-read technology.
200   Additionally, MACAU uses a computationally expensive Markov Chain Monte Carlo (MCMC) procedure, whi
201               Labeling an inert treatment as expensive medication led to stronger nocebo hyperalgesia
202 o remedy this problem: (i) develop new, less expensive methods to calculate system properties, or (ii
203 erical solvers based on more computationally expensive methods.
204 ng the lowest incremental QALYs for the most expensive moisturizer, the intervention was still less t
205 s revolution promises more reliable and less expensive molecular diagnostic tools for these diseases.
206           Currently, the development of less expensive, more active and more stable catalysts like he
207            Because of the time-consuming and expensive nature of the current standard technique for q
208 ins unclear, impeding the deployment of more expensive nets.
209 ly attractive, but they rely on unstable and expensive nicotinamide coenzymes that have prevented the
210 rations without resorting to computationally expensive numerical solution of reaction-diffusion equat
211 rgued to have resulted from the needs of our expensive offspring.
212                      However, this option is expensive, often limited by regulations such as catch sh
213  is considered a good alternative, albeit an expensive one.
214                    Our work does not require expensive optical fluorescence measurement techniques th
215 oblem in catalysis, as typically it involves expensive or corrosive oxidants or reaction media that a
216 effects of emissions are computationally too expensive or do not fully address complex atmospheric pr
217 and developing a new model was prohibitively expensive or time-consuming.
218 tep, instead of inhibiting methanogens using expensive or toxic chemical inhibitors, such as 2-bromoe
219 l-vein thrombosis a less burdensome and less expensive oral treatment option instead of a more expens
220 ith IVR as primary treatment for PDR is less expensive over 2 years, but both fall well below the acc
221 n thermocycling that uses time-consuming and expensive Peltier-block heating.
222 QR, $0.47-$1.69) were not statistically more expensive per ounce than products with 1 or more allerge
223   The current approaches use fixed lenses or expensive phased arrays.
224 als (Fe-N/C) have shown potential to replace expensive precious metals.
225 the standard catalysts require laborious and expensive preparations.
226 dergo unnecessary but physically painful and expensive procedure such as prostate biopsies repeatedly
227 ncer diagnostics without any complicated and expensive procedures.
228  The primary cost of artemisinin is the very expensive process used to extract and purify the drug fr
229 lihood model parameters in a computationally expensive process with downhill optimizers.
230 ulating mitochondrial mass, an energetically expensive process.
231  of viral proteins is the most energetically expensive process.
232 y distribution and cell migration, an energy-expensive process.
233 ces, without the need for time-consuming and expensive processes that are typically required for cata
234 concentration, or require time-consuming and expensive processing.
235 copic simulations, facilitate computation of expensive properties, and enable the development of pred
236 e bonuses in reimbursement, and low-quality, expensive providers will be penalized financially.
237 tion ultrastrong permanent magnets with less expensive rare-earth elements.
238 s through addition of a new network, without expensive re-computation of the entire MNA.
239                    To determine whether less expensive ready-made spectacles produce rates of spectac
240 pectrophotometric methods such as the use of expensive reagent not environmentally friendly, undefine
241 onse analysis, the microliter consumption of expensive reagents and hours of reaction and analysis ti
242 sitivity, need of specialised equipment, and expensive reagents for serological and molecular diagnos
243 gically meaningful parameters and/or rely on expensive reagents.
244 avoiding the need to perform computationally expensive regression methods with specific mathematical
245 onal burden but can satisfactorily avoid the expensive replacement of the entire membrane module afte
246 he FPB is substantially less computationally expensive, requires less information on a graph, and is
247               ML schemes are computationally expensive, requiring an eigenvalue decomposition (EVD) f
248 tically requesting a somewhat uncomfortable, expensive respiratory viral test, the result of which ma
249 ning and currently demands heavy reliance on expensive robotics in screening centers.
250 lso by light-emitting diodes, which are less expensive, safer, and more portable.
251  savings occurring when a hospital uses more expensive screening tests like polymerase chain reaction
252 lutegravir-based regimens and reduced use of expensive second-line boosted protease inhibitor regimen
253 dance and high costs of redox-active metals, expensive separators, active material crossover, and cor
254  direct electronic signal without the use of expensive signal transduction equipment and facilitates
255 is the gold-standard diagnostic test, but is expensive, slow, and may under-diagnose TB dissemination
256 sativus L., is considered as one of the most expensive spices worldwide, and as such, it is prone to
257        Saffron is one of the oldest and most expensive spices, which is often target of fraudulent ac
258 sive oral treatment option instead of a more expensive subcutaneous injection.
259            This brings a paradigm shift from expensive surgical treatment of cataracts to relatively
260 n would be sufficiently fast to render these expensive syntheses pointless.
261 ed PUFAs require rather long, laborious, and expensive syntheses.
262 trast) and target (no need for ultra-thin or expensive targets) constraints.
263 ET imaging is a widely applicable but a very expensive technology.
264  of heavy metal contamination are often very expensive, tedious and can only be handled by trained pe
265 ays provide results within 24h, but they are expensive, tedious and time consuming.
266 re the drug efficacy can be assessed in more expensive testing in vitro and in vivo.
267 depth sequencing that is 10- to 20-fold less expensive than conventional RNA-Seq.
268 $d_2^*$ and $d_2^S$ are more computationally expensive than measures based solely on the k-mer freque
269 y major teaching hospitals were $14,145 more expensive than nonteaching hospitals for AAA repair ($45
270  laparoscopic resection was significant less expensive than open resection in all subgroups, savings
271 econdary schooling is vital but will be more expensive than other interventions-investment of $22.6 p
272 lysts are significantly more active and less expensive than Pt/C and Ir/C, and are thus promising new
273 er to perform, easier to interpret, and less expensive than the 2-tier test method and which is bette
274    Seven of the drugs are substantially more expensive than their trial comparators.
275 a bauxite was approximately 23-33 times less expensive than with activated alumina.
276 e underlying reasons why cancer drugs are so expensive, the measures that are required to lower cost,
277 addition, MAb affinity chromatography can be expensive, the necessary MAb may be in limited supply, a
278 de an energetic contribution during the most expensive time of female reproduction, lactation, and th
279 nvincing and reliable method, but it also is expensive, time-consuming and often requires a large amo
280 e device manufacturing is significantly less expensive, time-consuming, and complex than traditional
281 ucleotides, they are typically prohibitively expensive to chemically synthesize, and unlike longer RN
282 ific, manually-annotated datasets, which are expensive to develop and thus limited in size.
283 sic plant cell wall, making it difficult and expensive to extract.
284     However, it is currently computationally expensive to perform hierarchical clustering of extremel
285 tomistic dynamics, which are computationally expensive to perform routinely.
286 ave short shelf lives, and are also the most expensive to produce, test, and store.
287 threat to health-care workers, prohibitively expensive to treat, and are therefore a serious public h
288 ies often result in delays in diagnosis, are expensive to treat, and can sometimes cause secondary lo
289  or severe unipolar depression is common and expensive to treat.
290 or wealth, such as burial goods or exotic or expensive-to-manufacture goods in household assemblages,
291  pain and shorter sick leave, DGHAL was more expensive, took longer, and provided a possible inferior
292 nced clinical staff using time-consuming and expensive tools and technologies.
293 n efficient alternative to the laborious and expensive traditional methods.
294 l precursors and does not require the use of expensive transition metals or ligands.
295 ning efforts are hindered by computationally expensive transition state barrier calculations.
296  today depend on detailed but cumbersome and expensive travel surveys for their calibration.
297    Bariatric surgery may be an effective but expensive treatment for NASH.
298                                NLISA is less expensive, uses less sample volume, is more rapid, and,
299  are predominantly fabricated by complex and expensive vacuum-based integrated circuit (IC) processes
300  of oak products as a cheaper alternative to expensive wood barrels was recently permitted in Europe,

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