ライフサイエンスコーパス: experimental animal model

1 y counteracted acute lung eosinophilia in an experimental animal model.

2 anges in differential renal blood flow in an experimental animal model.

3 ), using the conventional Fischer rat as the experimental animal model.

4 severity of aortic regurgitation (AR) in an experimental animal model.

5 ing microembolization to migraine aura in an experimental animal model.

6 iPFK-2 expression decreases tumor growth in experimental animal models.

7 sial temporal lobe epilepsy in humans and in experimental animal models.

8 s against many carcinogen-induced cancers in experimental animal models.

9 e less virulent than the wild-type strain in experimental animal models.

10 due in large part to the dearth of relevant experimental animal models.

11 inflammation in both human hypertension and experimental animal models.

12 s an important role in insulin resistance in experimental animal models.

13 ing the early stages of infection in several experimental animal models.

14 ponses have destroyed growing tumor cells in experimental animal models.

15 infection have been hindered by the lack of experimental animal models.

16 orodibenzo-p-dioxin and related compounds in experimental animal models.

17 inflammation in both human hypertension and experimental animal models.

18 is rare in animals and poorly reproduced in experimental animal models.

19 dance with several studies done in different experimental animal models.

20 is infection in both humans and unvaccinated experimental animal models.

21 s of CD4(+) regulatory T cells in humans and experimental animal models.

22 iding effective reduction of tumor burden in experimental animal models.

23 nset is limited by the lack of adjuvant-free experimental animal models.

24 ber D (NKG2D) mediates antitumor immunity in experimental animal models.

25 been developed for use in the clinic and in experimental animal models.

26 echanisms greater than that anticipated from experimental animal models.

27 mple of latent viral infection in humans and experimental animal models.

28 regs) to achieve this have been promising in experimental animal models.

29 brain injury and adversely affect outcome in experimental animal models.

30 has been hindered by a paucity of tractable experimental animal models.

31 d DC, and from analyses of their function in experimental animal models.

32 en studied extensively both in humans and in experimental animal models.

33 ions have also been identified in humans and experimental animal models.

34 ment and its disruption in human infants and experimental animal models.

35 tal programming can be modeled in a range of experimental animal models.

36 genetic mutations, and the complexity of the experimental animal models.

37 erum and many extraintestinal tissues in all experimental animal models.

38 Thus, in this experimental animal model, a high-titer vaccine-induced

39 In experimental animal models, administration of talactofer

40 ivities of the superantigens, and protect an experimental animal model against shock.

41 ting transmission of Borrelia burgdorferi in experimental animal models and are now being tested in h

42 tional abnormalities previously described in experimental animal models and can at least partially ac

43 Analysis of these gene products in experimental animal models and cell systems has led to a

44 Experimental animal models and epidemiological data indi

45 ng in pain conditions.SIGNIFICANCE STATEMENT Experimental animal models and human psychophysical stud

46 ls in inflammation-induced bone loss in both experimental animal models and human rheumatoid arthriti

47 g to the changes observed with aging in both experimental animal models and humans.

48 Drawing from experimental animal models and observational human studi

49 stroke pathology has been underestimated in experimental animal models and this may have contributed

50 as been established by cell culture studies, experimental animal models, and clinical trials.

51 sceptibility, the necessity for adjuvants in experimental animal models, and the often paradoxical ef

52 Experimental animal models are indispensable to the fiel

53 However, new experimental animal models are now available that will a

54 Studies in humans and experimental animal models are revealing the genetic and

55 Miniature pigs have been used as an experimental animal model, but they are still large and

56 circulation have been studied extensively in experimental animal models, but have failed to recapitul

57 e a human metabolic disease is induced in an experimental animal model by human hepatocyte transplant

58 malformations have been produced in multiple experimental animal models, by perturbing selected molec

59 Sustained rapid pacing in experimental animal models can produce severe biventricu

60 In experimental animal models, chronic stress leads to neur

61 These ligands were tested in an experimental animal model containing tumors that express

62 In human disease and experimental animal models, depressed Ca(2+) handling in

63 n the foundations of these approaches in new experimental animal models designed to test novel vaccin

64 section evaluates the use of agents given in experimental animal models during or after the onset of

65 Clinical, in-vitro and experimental animal model evidence continues to mount in

66 To review the clinical, in-vitro and experimental animal model evidence for the pathogenicity

67 These studies describe a novel experimental animal model for examining the spontaneous

68 To create an experimental animal model for HD, transgenic mice were g

69 iniature pigs in the world and is used as an experimental animal model for life science research.

70 ammatory demyelinating disease, providing an experimental animal model for multiple sclerosis.

71 g disease in mice provides a highly relevant experimental animal model for multiple sclerosis.

72 in, DJ-1, PINK-1 and LRRK2) and studies from experimental animal models has provided crucial insights

73 sease, together with earlier studies and new experimental animal models, has provided important and n

74 Several experimental animal models have been developed to study

75 Studies in experimental animal models have demonstrated that chemok

76 Several lines of evidence in experimental animal models have indicated the central ro

77 Previous studies in experimental animal models have reported that administra

78 , explanted and biopsied human material, and experimental animal models, have demonstrated that liver

79 omparing brain function between patients and experimental animal models; however, the relationship be

80 ce from patients with heart failure and from experimental animal models implicates effectors of innat

81 mobilization of human progenitor cells in an experimental animal model in response to different treat

82 rtension-induced renal damage, we derived an experimental animal model in which two genetically diffe

83 alth benefits have been attributed to CLA in experimental animal models including actions to reduce c

84 These findings in humans and in experimental animal models indicate the presence of pote

85 Progressive renal injury in humans and experimental animal models is characterized by tubular a

86 Due to the paucity of experimental animal models, little is known about how ho

87 Importantly, in experimental animal models, low dietary potassium intake

88 h Mycobacterium tuberculosis were used in an experimental animal model mimicking active tuberculosis

89 ed neutrophil counts and MPO activity, in an experimental animal model of ALI induced by systemic end

90 ion carbohydrate antigens was studied in the experimental animal model of alpha1,3galactosyltransfera

91 ce induction to the alpha-gal epitope in the experimental animal model of alpha1,3galactosyltransfera

92 Although the experimental animal model of anterior chamber-associated

93 An experimental animal model of atopic dermatitis induced b

94 A reproducible experimental animal model of fulminant hepatic failure (

95 to mediate collagen Ab-induced arthritis, an experimental animal model of immune complex-induced join

96 us CPs in modulating abscess formation in an experimental animal model of intraabdominal infection.

97 This hypothesis was tested in a unique experimental animal model of knockout mice for alpha1,3g

98 An experimental animal model of meningeal leukemia was deve

99 g gadolinium-labeled peptide, EP-1873, in an experimental animal model of plaque rupture and thrombos

100 ate it as a model of atopic dermatitis, this experimental animal model of pruritic inflammatory skin

101 tabolic acidosis and longer survival in this experimental animal model of septic shock.

102 Studies on experimental animal models of AF implicate a reduction i

103 Experimental animal models of AKI demonstrate that renal

104 iting cardiomyocyte apoptosis in 2 different experimental animal models of AMI.

105 he functions of natural killer (NK) cells in experimental animal models of atherosclerosis, it is not

106 pidemiologic studies, with some support from experimental animal models of atherosclerosis.

107 pidemiologic studies, with some support from experimental animal models of atherosclerosis.

108 The most commonly used experimental animal models of CHIKV infection are mice a

109 In experimental animal models of chronic renal injury, such

110 pigs are capable of restoring euglycemia in experimental animal models of diabetes.

111 responses are present in cells derived from experimental animal models of diabetes.

112 Endogenous IL-1Ra is produced in numerous experimental animal models of disease as well as in huma

113 an arthritis susceptibility locus mapped in experimental animal models of disease has been used to i

114 and enhanced neuronal synchrony observed in experimental animal models of epilepsy characterizes hum

115 mechanism of apoptosis in conditions such as experimental animal models of glaucoma and optic nerve t

116 he sympathetic nervous system alterations in experimental animal models of hypertension.

117 and Rhizopus oryzae has been demonstrated in experimental animal models of infection.

118 ded evidence of such processes in humans and experimental animal models of insulin-resistant diabetes

119 Immunologic studies involving experimental animal models of L. tropica infection are v

120 linical studies of liver disease and certain experimental animal models of liver injury conspicuously

121 bly through the development of UV-responsive experimental animal models of melanoma.

122 vant to the induction of disease symptoms in experimental animal models of MG, since numerous reports

123 sthenia gravis (MG) in humans, as well as in experimental animal models of MG.

124 omosome 17q, homologous to a locus linked to experimental animal models of multiple sclerosis, has be

125 cularization and pulmonary hypertension in 2 experimental animal models of PAH in vivo Up-regulation

126 In experimental animal models of sepsis telavancin was show

127 Experimental animal models of type 1 diabetes mellitus (

128 Several experimental animal models of viral-induced neurodegener

129 dvanced, at least in part, due to the use of experimental animal models, particularly the model of ce

130 Genome-wide association studies and experimental animal models point at a central role of th

131 Many fail because experimental animal models poorly predict human xenobiot

132 rally occurring plant estrogen in soy, in an experimental animal model previously reported to result

133 ition of FoxO1 function prevents diabetes in experimental animal models, providing impetus to identif

134 2)P beta-particle-emitting stents in various experimental animal models results in discordant effects

135 t and growth of carcinogen-induced tumors in experimental animal models, results from human studies a

136 This daring conclusion that is based on an experimental animal model should now be confirmed in hum

137 Currently, few experimental animal models similar to humans are availab

138 is lacking, non-randomized observational and experimental animal model studies were used.

139 Experimental animal models, such as transgenic mice, hav

140 Furthermore, arguments based on experimental animal models suggest a critical role of th

141 Recent studies involving experimental animal models suggest a role of the gut mic

142 Observational human studies and experimental animal models suggest that childhood exposu

143 Previous results from experimental animal models suggest that post-TBI hypergl

144 Experimental animal models suggest that statins may fost

145 Accumulated evidence from experimental animal models suggests that neuronal loss w

146 Experimental animal models support both the antibody and

147 Several published studies have used this experimental animal model system to demonstrate potentia

148 this review we focus on several widely used experimental animal model systems to highlight differenc

149 es in suppressing tumor cell regrowth in two experimental animal model systems.

150 alpha/beta) antagonist, both in vitro and in experimental animal model systems.

151 We review the recent clinical trials and experimental animal models that provide evidence in supp

152 In the experimental animal model, the hemodynamic, hematologic,

153 In experimental animal models, these compounds exhibited ex

154 As with all experimental animal models, they are flawed in one way o

155 known to inhibit DA-associated behaviors in experimental animal models through unknown mechanisms.

156 grating patient-based data with results from experimental animal models to gain deeper understanding

157 In this review we focus on experimental animal models to identify quantitative trai

158 that prolongs the survival of allografts in experimental animal models, to potentiate the immunosupp

159 This prompted the development of experimental animal models using controlled maternal cal

160 An experimental animal model was used to assess the importa

161 The development of experimental animal models was deemed essential for the

162 In an experimental animal model, we show that in vitro knockdo

163 mechanisms underlying these events using an experimental animal model, we show that inflammation may

164 of the present study was to determine in an experimental animal model whether CD8 T cells in pig xen

165 cilitates studies in platelets obtained from experimental animal models without the need of special d