ライフサイエンスコーパス: experimental method

1 rovide a verification of the validity of the experimental method.

2 ural models complementary to often-difficult experimental methods.

3 enyl derivatives with both computational and experimental methods.

4 oryl) was determined using computational and experimental methods.

5 que properties have been found using various experimental methods.

6 mbination of high-throughput theoretical and experimental methods.

7 y density functional theory calculations and experimental methods.

8 ed for nanoscale particles with contemporary experimental methods.

9 dynamic modeling due to the lack of reliable experimental methods.

10 ) has been investigated by computational and experimental methods.

11 Results are corroborated by nanorheological experimental methods.

12 ng almost impossible to detect using current experimental methods.

13 e (3)-IIIb (AAC) are determined with several experimental methods.

14 RNA targets as defined using high-throughput experimental methods.

15 ytical results can be verified with existing experimental methods.

16 oxide were investigated by computational and experimental methods.

17 n conjunction with comparative, imaging, and experimental methods.

18 a sets have been enriched by high-throughput experimental methods.

19 ell as describe and compare state-of-the-art experimental methods.

20 information not readily available with other experimental methods.

21 ty of up to 66% for interactions and 75% for experimental methods.

22 t uses spatial information from a variety of experimental methods.

23 chanical calculations and mass spectrometric experimental methods.

24 alculations and gas-phase mass spectrometric experimental methods.

25 cannot be visualized in 3D by using current experimental methods.

26 r the re-use and the explicit declaration of experimental methods.

27 ate the quality and reliability of different experimental methods.

28 tegrate such data from various complementary experimental methods.

29 ns, primarily because of lack of appropriate experimental methods.

30 e primary literature that provide details of experimental methods.

31 ments were documented with several different experimental methods.

32 nown due to limited structural resolution of experimental methods.

33 uctural model consistent with low resolution experimental methods.

34 dening, which cannot be obtained by existing experimental methods.

35 has been studied using both theoretical and experimental methods.

36 genomic scale that is a useful complement to experimental methods.

37 combination of genome-wide computational and experimental methods.

38 been developed to extend the impact of these experimental methods.

39 omodimers, because of limitations in current experimental methods.

40 d on a large-scale through computational and experimental methods.

41 ow was previously hidden, owing to a lack of experimental methods.

42 20.25 nN/mum, which agrees with macroscopic experimental methods.

43 tions were evaluated using computational and experimental methods.

44 kness are often more relevant when comparing experimental methods.

45 accurately determined with state of the art experimental methods.

46 dermal flux data collected using traditional experimental methods.

47 As a complement of experimental methods, a support vector machine based-met

48 , most Web-based psychological research uses experimental methods, a surprising number use college st

49 ry to characterization due to the paucity of experimental methods able to probe the mobility and dens

50 Recently developed experimental methods allow direct single-base profiling

51 The application of complementary experimental methods, along with quantum chemical calcul

52 ffa et al. are largely due to differences in experimental method and procedure, rather than to the te

53 tes that have been supported by a variety of experimental methods and (iii) polymorphisms in miRNA se

54 isms inside synapses, yet recent advances in experimental methods and biophysical understanding have

55 of public open data across a broad range of experimental methods and conditions.

56 ances DNA binding as monitored by a range of experimental methods and confirmed by multiscale modelin

57 These results cast doubt on certain experimental methods and demonstrate that a common assum

58 s for activation of CpH and c-C(5)H(8) using experimental methods and describe a new product found fr

59 Simulations provide guidance for developing experimental methods and future instrument design by qua

60 The accurate reporting of experimental methods and materials, including the sex an

61 continue efforts to improve the reporting of experimental methods and materials.

62 f Blood, Flamm et al combine high-throughput experimental methods and multiscale computer simulations

63 ral protein-protein interaction information, experimental methods and other statistical information.

64 y available data and provides information on experimental methods and phenotypic results, including r

65 pressed in prostate cancer using independent experimental methods and prostate cancer specimens.

66 Our experimental methods and sampling strategy are validated

67 Emergent high-throughput experimental methods and sequencing technologies allow u

68 regions in proteins presents a challenge for experimental methods and so recently there has been much

69 With the development of experimental methods and technology, we are able to reli

70 The experimental methods and their relative advantages and d

71 of ion pairs in solution, since few general experimental methods are available for obtaining such in

72 Few experimental methods are available to directly visualize

73 and q(ox,red) encountered with the different experimental methods are discussed in terms of instrumen

74 h information on these questions, but better experimental methods are needed to detect and characteri

75 tes the use of randomized controlled trials, experimental methods are not always feasible, and resear

76 Although published data from traditional experimental methods are the primary sources of evidence

77 Multiple experimental methods are used to unambiguously verify th

78 xt, five criteria, as well as the associated experimental methods, are developed to evaluate the effi

79 n folding or unfolding, unlike most in vitro experimental methods, are performed on a single molecule

80 Herein, we survey the progress in experimental methods as well as the corresponding analys

81 es, highlighting the key species studied and experimental methods available.

82 An experimental method based on determining the initial rea

83 Here, we describe an experimental method based on reaction-diffusion phenomen

84 ate, most published approaches have compared experimental methods by counting the total number of fea

85 The experimental methods by which chelators are assessed for

86 Here, we present a transcriptome-wide experimental method, called "degradome sequencing," to d

87 The findings presented here suggest that our experimental method can be applied for the enrichment of

88 Consequently, this experimental method can be used to determine how well th

89 Several experimental methods can be used to visualize dislocatio

90 tes how the combination of computational and experimental methods can leverage metagenomic data to ch

91 Such difference between different experimental methods can provide insight into the system

92 We also show that most single-cell experimental methods cannot distinguish between qualitat

93 Experimental methods capable of generating sets of co-re

94 Despite the wide availability of robust experimental methods capable of resolving structural det

95 In this study, a steady-state concentration experimental method combined with a spherical diffusion

96 the high cost and technique difficulties in experimental methods, computationally predicting the bin

97 logists to a high level of detail, including experimental methods, conditions and interacting domains

98 Different experimental methods confirmed that hybrid clones identi

99 we found that the results obtained from both experimental methods consistently agreed.

100 ly limited by thermal broadening, this novel experimental method could be used to detect variations i

101 These straightforward calculations and the experimental methods described herein may be useful in g

102 An analysis of experimental methods described in the literature to dete

103 As traditional experimental methods designed to test out essential prot

104 The experimental method developed here holds promise for det

105 The experimental methods developed to carry out this work ar

106 The experimental methods discussed involve M-centered (S0 --

107 Current experimental methods do not separate the influence of th

108 ive site, is still not well characterized by experimental methods due to its high degree of flexibili

109 poxia on these outcomes; however, only a few experimental methods enable both precise control over ox

110 this environment is difficult to access with experimental methods, especially under flow conditions a

111 Numerous experimental methods exist but, for the most part, they

112 While many experimental methods exist for generating such specifici

113 netic barriers, which, with less informative experimental methods (fluorescence, etc.), are often con

114 e instrument that can establish a replicable experimental method for clinical trials of blood glucose

115 imple, fast, and theoretically substantiated experimental method for determination of improved select

116 These results provide an experimental method for determining the polaron relaxati

117 This approach represents an experimental method for distinguishing solvation from co

118 Introducing an experimental method for high-throughput colony imaging,

119 traditionally represented the gold-standard experimental method for identifying regulatory elements,

120 ional mode to electric field, can provide an experimental method for parsing such interactions into t

121 We demonstrate a high-resolution in situ experimental method for performing simultaneous size cla

122 We propose an experimental method for probing biological networks, ana

123 Tn-Seq is an experimental method for probing the functions of genes t

124 We present a novel experimental method for quantifying the mechanical behav

125 ement obtained supports the potential of the experimental method for the evaluation of interactions i

126 We present a combined computational and experimental method for the rapid optimization of protei

127 Here, we present an experimental method for transcriptome-wide profiling of

128 llenge is the fact that most high-throughput experimental methods for characterizing transcripts (suc

129 Here, we review key experimental methods for CyTOF that enable accurate data

130 Our theoretical results motivate new experimental methods for decomposing protein noise level

131 Experimental methods for describing critical residues ar

132 erve as model systems for the development of experimental methods for determining the structures of p

133 RNA regulation, and demonstrate the power of experimental methods for establishing comprehensive inte

134 There have been a series of biological experimental methods for finding essential proteins; how

135 The development of experimental methods for genome scale analysis of molecu

136 However, current high-throughput experimental methods for identifying RBP targets, such a

137 Existing experimental methods for in ovo sexing require taking sa

138 Current experimental methods for inhibitory perturbation are unl

139 s well as mRNA profiling and high-throughput experimental methods for mapping protein-binding sites i

140 While experimental methods for measuring bulk dielectric const

141 We review experimental methods for measuring fast protein folding

142 noisy data that require validation by other experimental methods for measuring gene expression.

143 Some of these direct experimental methods for miRNA target identification hav

144 Experimental methods for modulating H2S levels, includin

145 s necessitate the development of new, faster experimental methods for providing structural informatio

146 modeled structures, and complements existing experimental methods for specificity determination.

147 Here we discuss two complementary direct experimental methods for studying transcription factors

148 Although confirmed by a multitude of experimental methods for various systems, its mechanism

149 The proposed experimental method generalizes Chidsey's method for pha

150 gnitive brain regions, but until recently no experimental method has been available to directly test

151 e does have limitations and as yet a general experimental method has not been realized.

152 A series of experimental methods has been introduced, which in the c

153 Experimental methods have been developed to survey the p

154 Although experimental methods have been proposed to dissect multi

155 Genome-enabled bioinformatic/experimental methods have comprehensively identified the

156 However, experimental methods have difficulty in solving disorder

157 Advanced experimental methods have provided access to explore the

158 Previous experimental methods, however, have focused on sheets th

159 However, limitation in experimental methods impedes the progress towards the id

160 Electron Microscopy (3DEM) has become a key experimental method in structural biology for a broad sp

161 y approach that integrates computational and experimental methods in an iterative way to gain a compr

162 approaches have been developed to complement experimental methods in discovery of miRNAs that express

163 Owing to the huge cost associated with experimental methods in identifying optimal drug combina

164 , the makeup of the physical environment and experimental methods in the outcome of microarray analys

165 We present an experimental method including error analysis for the mea

166 The recent advances in experimental methods including chromatin capture techniq

167 Numerous experimental methods, including kinetic studies, filtrat

168 This assumption was verified by different experimental methods, including nuclear magnetic resonan

169 Recently developed high-throughput experimental methods, including protein binding microarr

170 y investigated by a combination of different experimental methods, including steady-state and transie

171 Primary among these are choices of experimental method, instrumentation and spectral interp

172 be valuable as a first approach for guiding experimental methods investigating protein-protein inter

173 However, the vast majority of experimental methods involve either bulk-averaging techn

174 Here we use a novel in situ experimental method involving olivine micro-reactors and

175 A new experimental method is presented that allows this.

176 This combination of computational and experimental methods is useful in defining more accurate

177 s method was comparable to those of previous experimental methods (<5%).

178 r to overcome the shortcomings of biological experimental methods, many computational methods have be

179 Our approach, combined with more traditional experimental methods, may be useful for identifying acet

180 However, current experimental methods (MNase-ChIP, MNase-Seq) sample nucl

181 mbination of computational methodologies and experimental methods, new insights into the reactivity o

182 the comprehensiveness and large diversity of experimental methods, nomenclatures and publication sour

183 dem mass spectrometry (MS/MS) has become the experimental method of choice for high-throughput proteo

184 metabolic flux analysis (MFA) has become the experimental method of choice to investigate the cellula

185 can be investigated by the well-established experimental method of fluorescence anisotropy decay.

186 , and the use of metabolic inhibitors is one experimental method of simulating ischemia.

187 However, unlike multiple experimental methods of breaking tolerance, we report in

188 Experimental methods of increasing cost and complexity a

189 Conventional experimental methods of studying the human genome are li

190 nding of social-contagion processes, and our experimental method offers numerous new opportunities to

191 Comprehensive experimental methods, on the other hand, are limited to

192 possible, yet a major challenge is comparing experimental method performance on the basis of metabolo

193 fects are compared here in terms of history, experimental method, performance and prospective cooling

194 Our experimental method permits direct measurement of capsul

195 These results, along with the experimental methods presented herein, should guide futu

196 Recent advances in experimental methods provide increasing evidence that pr

197 Our experimental method provides a novel means for trapping

198 Our experimental method provides a novel platform to study t

199 ions of bacterial isolates with genomics and experimental methods provides opportunities for 'top-dow

200 Most experimental methods report on the long-lived functional

201 Here, we describe an experimental method (shotgun proteolysis) based on rando

202 ng these bioinformatics tools with classical experimental methods should accelerate QTL gene identifi

203 Our experimental methods show that our approaches effectivel

204 Constraints from both experimental methods showed the presence of short-range

205 easure the rate of this reaction directly by experimental methods, so it has been evaluated by examin

206 Important additional fields deal with new experimental methods, strain information, pathogenicity

207 We report the development and validation of experimental methods, study designs, and analysis softwa

208 Experimental methods such as high-throughput chromosome

209 the interaction data obtained from different experimental methods such as immunoprecipitation and two

210 High throughput experimental methods such as tiling arrays or 5' SAGE/ES

211 anding of macromolecular structure come from experimental methods, such as X-ray crystallography, and

212 Rigorous experimental methods suppress differences among study pa

213 a coli CcdB as the test case, we describe an experimental method termed saturation-suppressor mutagen

214 Experimental methods testedincluded the use of "syntheti

215 sly propose or make changes to improve their experimental methods than a control group, who performed

216 Competition ChIP is an experimental method that allows transcription factor (TF

217 Experimental methods that "count" the number of ions the

218 Progress is dependent on experimental methods that accurately measure the frequen

219 Experimental methods that allow examination of the intac

220 Traditionally, they are studied by experimental methods that are necessarily perturbative:

221 miting step in the metastatic process; thus, experimental methods that can be used to interrogate the

222 ture determination, as well as used in other experimental methods that can provide tertiary restraint

223 ons presents a challenge because it requires experimental methods that can track the chemical and str

224 Here, we describe the statistical and experimental methods that illustrate this approach and d

225 hile the focus of this progress report is in experimental methods, their concerted use with theoretic

226 Existing experimental methods therefore probe folding mechanisms

227 r reorientational dynamics, is a widely used experimental method to assess the motion of the protein

228 We have therefore employed an independent experimental method to determine the folding rate.

229 Our work introduces a hybrid computational/experimental method to determine the importance of struc

230 In this report, we develop an experimental method to determine the plane stress state

231 eover, this study establishes a modeling and experimental method to elucidate the structural dynamics

232 This information provides an experimental method to explore the underlying physical c

233 m limit torque measurements provide a direct experimental method to identify and distinguish Weyl and

234 In this study, we introduce an experimental method to measure ATP consumption of active

235 This finding suggests a novel experimental method to probe the stability of bioorganic

236 Gel electrophoresis is a powerful experimental method to probe the topology of DNA and oth

237 nd slight changes of the chamber sealing, an experimental method to quantify gas leakage fluxes by us

238 anscriptome diversity, and a high-throughput experimental method to quantitatively assess predictions

239 We used an experimental method to reduce global cellular noise and

240 proved in recent years to be a very powerful experimental method to study superfluid turbulence.

241 Here we use theoretical and experimental methods to analyze interactions of mouse wh

242 In this work, we used computational and experimental methods to assess multiple negative regulat

243 We used quasi-experimental methods to assess the early performance of

244 d to as ligands), shown by computational and experimental methods to bind to each of 2 sites within t

245 Here we used bioinformatic and experimental methods to characterize Alg glycosyltransfe

246 essential part of monolayer function, simple experimental methods to characterize monolayer mechanica

247 Theory and experimental methods to characterize nanoparticles in te

248 protein interactions and briefly review the experimental methods to detect protein interactions.

249 We suggest experimental methods to determine which types of coevolu

250 Despite this realization, experimental methods to directly select for increased yi

251 stration of the combination of modelling and experimental methods to enable the discovery of compound

252 developing treatments, review the available experimental methods to evaluate the therapeutic potenti

253 However, experimental methods to identify associations between ln

254 We used a combination of computational and experimental methods to identify promoters for eight add

255 In this study we combine computational and experimental methods to identify splice variants in embr

256 rly understood because of the lack of simple experimental methods to identify this property and its i

257 Here, we use computational and experimental methods to investigate how DeltaPsim instab

258 characterization of micro-RNAs awaits robust experimental methods to knock-down a micro-RNA as well a

259 In particular, advances in experimental methods to map regulatory networks in micro

260 naling and advance Ras-targeting strategies, experimental methods to measure Ras dynamics are require

261 nt water relations is limited by the lack of experimental methods to measure water fluxes in soil and

262 enable the use of data from high-throughput experimental methods to predict complex phenotypes such

263 for the first time, using computational and experimental methods to provide an understanding of aden

264 for the first time, using computational and experimental methods to provide an understanding of the

265 We discuss two experimental methods to reveal ChR2 current during an ac

266 We use experimental methods to show where linear order is also

267 The experimental methods to solve RNA-protein interaction pr

268 At the same time, it provides simple experimental methods to study the biomolecular reaction

269 ht differences and the second involves using experimental methods to test the consequences of disrupt

270 mental results and a closer approximation of experimental methods to the naturalistic demands inheren

271 lts provide strong motivation to develop new experimental methods to track position and orientation o

272 rescentus as a model, we exploit genome-wide experimental methods to uncover the functions of CcrM, a

273 largely unknown, partly owing to the lack of experimental methods to visualize and quantify growth.

274 Experimental methods (TOF-SIMS, X-ray photoelectron spec

275 sms proposed to date and how using different experimental methods (trenching, girdling, microcosms),

276 irrespective of the protein, denaturant, or experimental method used.

277 inding affinity benchmark and show that both experimental methods used for affinity measurements and

278 Experimental methods used for determining RNA 3D structu

279 Advances in the experimental methods used for mapping these properties w

280 The experimental methods used for this purpose are laborious

281 ormational flexibility, it suggests that the experimental methods used here could provide training se

282 However, experimental methods used in these studies may accentuat

283 esistance and splanchnic vasodilatation) and experimental methods used to act on the mechanisms that

284 The experimental methods used to identify DNA-binding protei

285 Because of the experimental methods used to measure binding or affinity

286 Our approach overcomes the limits of earlier experimental methods using short model peptides, and the

287 An experimental method was introduced to accurately measure

288 A wide range of experimental methods was used in order to characterize t

289 A combination of computational and experimental methods was used to examine the structure-r

290 e, and cyanoacetylene in helium, using a new experimental method we call optically selected mass spec

291 re, using a combination of computational and experimental methods, we further characterize this symme

292 Both computational and experimental methods were applied to a set of designed "

293 Three different experimental methods were proposed and evaluated.

294 tion sets that were determined with the same experimental methods were strikingly similar.

295 NA methylation has been determined mostly by experimental methods, which are not only prone to bench

296 Here, we combine experimental methods with clustering analysis of protein

297 udy on Mg/S system is conducted by combining experimental methods with computational approach.

298 a framework for combining computational and experimental methods with different time scales for the

299 Here, we used two experimental methods with distinct noise sources and lim

300 cific traits are widely sought, but reliable experimental methods with which to identify functionally