ライフサイエンスコーパス: experimentation

1 ned the ground truth for our data set before experimentation.

2 ssembly can be done just before the start of experimentation.

3 munity structure and generate hypotheses for experimentation.

4 eutic concepts prior to in vivo large animal experimentation.

5 rge-scale data, and to assist methodological experimentation.

6 sesses pharmacokinetics suitable for in vivo experimentation.

7 1 +/- 0%, respectively, over the 175 days of experimentation.

8 es to many compounds and using them to guide experimentation.

9 the basis for further functional and genetic experimentation.

10 rbations that are computed on-the-fly during experimentation.

11 al history, system-level theory, and careful experimentation.

12 r utility in complex chemical and biological experimentation.

13 ficient for identification and/or downstream experimentation.

14 hat is in our view unnecessary and excessive experimentation.

15 and therefore can be the subject of further experimentation.

16 vide a scalable vertebrate model for in vivo experimentation.

17 r exploiting extant data to rationally guide experimentation.

18 s Candidatus Brocadia Fulgida throughout the experimentation.

19 bodies so that they can be directly used for experimentation.

20 ccessible embryos, juveniles, and adults for experimentation.

21 th high-throughput data sets for prospective experimentation.

22 shown to contain the epitope for this Ab by experimentation.

23 w predictions, which are verified by further experimentation.

24 e making long-standing questions amenable to experimentation.

25 tools for disease modelling and therapeutic experimentation.

26 hput preparation of live animals for optical experimentation.

27 a process commonly used in immune population experimentation.

28 ntrol mice (n=30) were isolated for in vitro experimentation.

29 indings, but also being a catalyst for novel experimentation.

30 fore become rate-limiting in forward genetic experimentation.

31 of this evidence comes from high-throughput experimentation.

32 y provides a powerful resource for in silico experimentation.

33 itative studies have largely used laboratory experimentation.

34 ving computational modeling and quantitative experimentation.

35 r long-term culture and large-scale in vitro experimentation.

36 , yet are poorly constrained in modeling and experimentation.

37 explore scientific reasoning through direct experimentation.

38 modium parasites are key drivers for further experimentation.

39 and ethical pressures placed on animal-based experimentation.

40 biology and help form hypotheses for further experimentation.

41 response and provide prioritized targets for experimentation.

42 nline labor markets as a tool for behavioral experimentation.

43 an exciting new platform for high-throughput experimentation.

44 lity of early stages of human development to experimentation.

45 al-and-error process that requires laborious experimentation.

46 ficans was dominant (>50%) after 6 months of experimentation.

47 nes or proteins that emerge from large-scale experimentation.

48 cy as tractable systems for unbiased genetic experimentation.

49 characteristics to optimize high-throughput experimentation.

50 This prediction was validated by experimentation.

51 various lipid membranes without the need for experimentation.

52 taxis by combining theoretical modeling with experimentation.

53 onal Committee of Ethic Reflection on Animal Experimentation.

54 eceived ethics committee approval for animal experimentation.

55 potentially reducing the need for expensive experimentation.

56 pieces were stored in BSS until the time of experimentation.

57 aveled through the interplay of modeling and experimentation.

58 formation is difficult and requires years of experimentation.

59 sphonoacetates utilizing parallel microscale experimentation.

60 gen interactions without the need for animal experimentation.

61 he data, and predicts if and how to continue experimentation.

62 ly than females that were not flushed during experimentation.

63 ified in cell culture and preclinical animal experimentations.

64 models stand the test of time and hold up to experimentation?

65 gine: a pre-dosed microscale high-throughput experimentation additives platform enables rapid, serend

66 Test results from the DEP experimentation after comparing with fluorescent images

67 Future experimentation aimed at broadening the substrate specif

68 High-throughput experimentation allows for identifying the optimal ligan

69 ecreases the number of animals necessary for experimentation, allows division of the sample from a ho

70 eved through traditional in vivo or in vitro experimentation alone.

71 play important roles in influencing smoking experimentation among students.

72 The combination of experimentation and CFD is a successful ECs calibration

73 Here we use a combination of multi-scale experimentation and computation to show that water is an

74 A dual approach pairing experimentation and computational fluid dynamics (CFD) w

75 be used with an extensive range of external experimentation and data acquisition hardware, and inclu

76 y powerful model of ARS, amenable to in vivo experimentation and development of potential therapies.

77 tes new potential for direct kinase activity experimentation and diagnostics on patient blood, bone m

78 Subsequent laboratory experimentation and field investigations revealed how re

79 enzymological data accrued from a century of experimentation and generated a genome-scale enzyme-inhi

80 ation of embryonic stem cells using rigorous experimentation and implicate the methyltransferase Dnmt

81 Second, he was courageous in experimentation and innovation, applying new development

82 Here we combined experimentation and mathematical modeling to investigate

83 tion factor NF-kappaB in microglia combining experimentation and mathematical modeling, using TNFalph

84 High pressure and temperature experimentation and modeling in metal-silicate systems u

85 ircuit is best studied with a combination of experimentation and modeling.

86 e-cell recording and, using a combination of experimentation and modelling, electrophysiological para

87 ds we develop, coupled with careful clinical experimentation and observation and, yes, still, a fair

88 Using in vivo experimentation and physical modelling we reveal that th

89 ingly, these in silico data can direct ADMET experimentation and profoundly impact the progression of

90 les, TB-ATC provides distinct advantages for experimentation and quantification of applied forces and

91 total, these steps should take 6-8 weeks of experimentation and should result in the evolution of a

92 ver, remains poorly understood, despite much experimentation and speculation.

93 esent as hydrous TcO2-like chains throughout experimentation and that Tc's increased resistance to re

94 7 model represents a valuable tool to pursue experimentation and therapeutic approaches that may be d

95 late disease can significantly reduce animal experimentation and time-to-the-clinic.

96 ats, which had normal binaural hearing until experimentation, and congenitally deaf white cats, which

97 tal goals, including sweatshop labor, animal experimentation, and drone strikes that result in civili

98 ces; they learn from statistics and informal experimentation, and from watching and listening to othe

99 ining logic-based network modeling, in vitro experimentation, and gene expression profiles from patie

100 evolutionary modelers to enter the world of experimentation, and help to strengthen the bond between

101 sion that includes discovery, demonstration, experimentation, and verification.

102 The local ethics committee of animal experimentation approved all investigations.

103 Scripts created for the experimentation are available at http://m4m.ugr.es/SupIn

104 gh genetic, biochemical, and cell biological experimentation as well as by mathematical modeling.

105 isms are governed by droplet size; therefore experimentation at length scales typical of those encoun

106 microfluidic approach allows high-throughput experimentation at relevant length scales and with adjus

107 course of more than a century of laboratory experimentation, Bacillus subtilis has become "domestica

108 etical and computational analysis as well as experimentation by emphasizing two strategies found in a

109 , we combine network analysis and functional experimentation by using a hybrid approach in which grap

110 id foundation upon which further prospective experimentation can be developed.

111 of reaction volumes, so that high-throughput experimentation can be performed more economically and m

112 lant construction to the start of behavioral experimentation, can be completed in approximately 2-6 w

113 mplantation and preparation to begin in vivo experimentation, can be completed in ~3-8 weeks.

114 als providing a miniaturized high-throughput experimentation capability that was used to study a chal

115 croscale, allowing more precise quantitative experimentation capturing multi-scale aspects of complex

116 tructured and standardized protocols for the experimentation, collection and dissemination of data.

117 Morpholino-based experimentation confirmed that modulation of the seroton

118 Ideally, data-driven experimentation could be used to learn accurate models f

119 Thus, two lines of experimentation demonstrate that PRMT1 acts on FMRP in c

120 In vitro experimentation demonstrated that carrot broth-enhanced

121 Further in vitro experimentation demonstrated that mAb 26.4 can opsonize

122 Further experimentation demonstrated that some abiotic Po(v) gen

123 Here we extend such experimentation drastically, beyond dyads and beyond lab

124 Drug experimentation during adolescence is associated with in

125 expand the boundaries of neurophysiological experimentation, enabling analytical methods that were p

126 Pr) agonists] involve relapsing cycles, with experimentation/escalating use, withdrawal/abstinence, a

127 for organ engineering and regeneration, for experimentation ex vivo and potential clinical applicati

128 reviously unreported utility high-throughput experimentation for mechanistic elucidation is also desc

129 automation platform enabling high-throughput experimentation for synthetic route scouting to identify

130 Ldlr(-/-) mice, suggesting future courses of experimentation for the characterization of such epitope

131 requires execution of large-scale structured experimentation for which laboratory automation is neces

132 optimization of spectrometry via closed-loop experimentation) for the robust and fully automated mult

133 fied skin as the most antigenic, with recent experimentation from our laboratory finding a direct cor

134 Purpose Reproducibility of scientific experimentation has become a major concern because of th

135 Single-molecule experimentation has contributed significantly to our und

136 rial chemistry more broadly, high-throughput experimentation has greatly facilitated innovation in sm

137 structure-guided biophysical and biochemical experimentation, has led to an improved understanding of

138 Clinical studies and animal experimentation have shown that colonic inflammation is

139 While animal experimentations have spearheaded numerous breakthroughs

140 bers of animals can be economically used for experimentation; however, high-throughput methods for im

141 tification were performed by high-throughput experimentation (HTE) and led to a unique base/catalyst

142 ntification was performed by high throughput experimentation (HTE) and led to the Xantphos/palladium

143 coupling, developed using a high-throughput experimentation (HTE) technique, enabled a full SAR anal

144 of the characteristics of medicines through experimentation." Ibn Sina proposed applying logic to th

145 to demonstrate significance, our preliminary experimentation identified a high correlation between GR

146 Experimentation in 3-D presents challenges, especially w

147 Based largely on experimentation in anesthetized or reduced preparations,

148 f associative learning theory and behavioral experimentation in animals and has become a topic of con

149 inear dynamical systems analysis and in vivo experimentation in developing animals, we show that nano

150 rent review highlights elegant, reason-based experimentation in discovering RNA-directed biological p

151 isease, helping alleviate problems involving experimentation in humans that cannot be done practicall

152 he discovery of a unique platform to support experimentation in low-temperature plasma science.

153 validated ChR2 model will facilitate virtual experimentation in neural and cardiac optogenetics at th

154 diffusion-convection model through in vitro experimentation in systems with known diffusion coeffici

155 known caveats and limitations of optogenetic experimentation in the context of addressing these chall

156 ration of the retina, opening new avenues of experimentation in the field.

157 ng fossils of transitional forms with direct experimentation in the laboratory via genome manipulatio

158 s of environmental samples and physiological experimentation in the laboratory with defined microbial

159 lergy research that have arisen from in vivo experimentation in the mouse, with a focus on models of

160 To this end, we performed extensive experimentation in vitro and in vivo in an attempt to ve

161 demonstrated, via gain- and loss-of-function experimentation in vitro and in vivo, that miR-130/301-s

162 disease gene network coupled with molecular experimentation in vivo, these findings clarify the expa

163 Because this is not yet possible solely by experimentation in vivo, we combine computational modeli

164 utility of active learning-driven biological experimentation in which the set of possible phenotypes

165 is improvement may facilitate more efficient experimentation in which transformation efficiency is cr

166 erates song variability that underlies vocal experimentation in young birds and modulates song variab

167 Functional experimentation including viral rescue and complexome pr

168 odel captures the underlying dynamics of the experimentation, including an initial predation-delay at

169 HSCs support multidisciplinary translational experimentation, including the study of human hematopoie

170 These 2 lines of in vivo experimentation independently demonstrate an important r

171 Results from additional experimentation indicate that Bfd must bind to BfrB to p

172 Combined computational modelling and experimentation indicated that cell stimulation was high

173 Modeling and experimentation indicated that retroactivity may result

174 Physiologically relevant experimentation is hindered by the low endogenous concen

175 As human experimentation is limited, animal models have been deve

176 Further experimentation is needed to test our results and both Q

177 Further experimentation is required to more fully characterize t

178 r may suggest areas where further biological experimentation is required.

179 l with a 'pseudotime' where true time series experimentation is too difficult to perform.

180 hypotheses made by gap filling tools require experimentation, it is challenging to benchmark performa

181 Microfluidic systems miniaturise biological experimentation leading to reduced sample volume, analys

182 omic data as well as by in vitro and in vivo experimentation, mapping studies continue to characteriz

183 application of miniaturized high-throughput experimentation methods to resolve synthetic chemistry c

184 including cellular and molecular biochemical experimentations, morphological observations and electro

185 And third, meaningful experimentation must become acceptable in school systems

186 Experimentation of PCa cells with ERG overexpression or

187 al ecological processes, however, replicated experimentation on biological dispersal is lacking, and

188 ue level, we discuss optogenetically enabled experimentation on cell-cell coupling, alteration of con

189 dangerment of the devil population precludes experimentation on large experimental groups, those exam

190 ate and atmosphere simulator for multifactor experimentation on natural or artificial ecosystems.

191 The trends revealed from experimentation on post-mortem skin are then used to ide

192 In contrast, we show, by replicated experimentation on the spread of the ciliate Tetrahymena

193 osophila, and human, and also through direct experimentation on two different human cell lines.

194 mount of diffraction data in high-throughput experimentation, one can streamline the process of delin

195 ngs that chimpanzees with prior histories of experimentation, orphanage, illegal seizure, or violent

196 After extensive experimentation, outcomes of a first clinical normotherm

197 ustomized control software, enabling modular experimentation packages and automated data pre-analysis

198 Thus, further preclinical experimentation, possibly using mouse models that more f

199 that computational simulations, validated by experimentation, predict that glycolytic production of A

200 y a common event and often requires a mix of experimentation, predictive computations, and luck.

201 ed to compile detailed results of polymerase experimentation, presenting them in a dynamic view to in

202 rent predictions and decide when to stop the experimentation process.

203 e learning is a powerful tool for guiding an experimentation process.

204 g reactions was evaluated by high-throughput experimentation protocols.

205 creasingly, the capacity for high-throughput experimentation provided by new imaging modalities, cont

206 l disorders are part of a repeating cycle of experimentation recurring since the mid-18th century.

207 We use ARTIMMUS to perform novel in silico experimentation regarding the priming of CD8Treg cells b

208 Computational modeling and experimentation reveal that complex effects of caveolin

209 Mathematical modeling and experimentation revealed greater apoptosis of Listeria-s

210 Further experimentation revealed that even the earliest drops in

211 Modelling and additional experimentation revealed that this was most likely due t

212 s engage in higher rates of drug and alcohol experimentation, risky sexual practices, and criminal ac

213 Together, they show an evolutionary experimentation similar to the iterative evolutions of g

214 timulation, will follow a similar pattern of experimentation, speculation and marginalization.

215 However, most in vitro experimentation studies that are used to evaluate micron

216 Prior biophysical experimentation suggested that divalent ions associate w

217 Further, in silico experimentation suggests that dynamics of CD8Treg primin

218 set of transcribed protein-coding genes and, experimentation suggests, might control the expression o

219 ults from both computational simulations and experimentation support a model in which the Nck/N-WASp/

220 stematic Review Centre for Laboratory Animal Experimentation (SYRCLE) approach.

221 High-throughput experimentation techniques provided successful reaction

222 nditions was performed using high-throughput experimentation techniques.

223 After 18weeks of experimentation, the animals were stored on ice at 4 deg

224 Despite decades of experimentation, the mechanisms by which critical period

225 Together with functional experimentation, these data are rapidly enabling researc

226 With some adaptation and further experimentation, this approach, applied on a parallel ar

227 ce that provides natural avenues for further experimentation through the development of new sampling

228 en are inaccessible for controlled and rapid experimentation, thus limiting studies to the evaluation

229 has the potential to expand single-molecule experimentation to a wider range of researchers and expe

230 work, we combine mathematical modeling with experimentation to address this question.

231 REACH regulation requires the use of animal experimentation to assess the risk of industrial chemica

232 f specific biological mysteries via creative experimentation to broad technological advances allowing

233 Even though translation from animal experimentation to clinical practice is challenging, the

234 riant carriers for endolysosomal patch-clamp experimentation to confirm key in vitro findings.

235 We used high throughput experimentation to define stereoconvergent Suzuki-Miyaur

236 olution analysis, molecular simulations, and experimentation to define the interactions between the T

237 es, thus demonstrating the value of parallel experimentation to develop novel, substrate specific res

238 gingival tissues and will inform mechanistic experimentation to dissect the role of miRNAs in periodo

239 ferent models and indicate areas for further experimentation to elucidate the mechanism of these enzy

240 in opaque and that are in need of additional experimentation to enrich our understanding of how visio

241 Thus AMT opens the world of experimentation to evolutionary theorists.

242 we combined mutual information analysis and experimentation to identify coevolving positions and fou

243 resent a method that uses in vivo randomized experimentation to identify influence and susceptibility

244 re we combine mathematical modelling and lab experimentation to investigate the predation of an impor

245 Enrichment tests are used in high-throughput experimentation to measure the association between gene

246 e a combination of mathematical modeling and experimentation to provide evidence that, counter-intuit

247 To reverse these outcomes, a strategy of experimentation to realign incentives for providers with

248 Here we integrate theory and experimentation to show that niche differences collectiv

249 evel computational modeling and quantitative experimentation to solve this puzzle.

250 reas experimental systems are open to direct experimentation to test hypotheses of selection or ecolo

251 s) and further utilized in context of guided experimentation to verify false positive outcomes.

252 These data derive from careful experimentation under conditions relevant for the atmosp

253 This new insight from field experimentation under hot and dry conditions, which will

254 The control experimentation using 5mg/mL bovine serum albumin in PBS

255 onadotropin surge, a result at variance with experimentation using genetic ablation of PGR signaling.

256 We encourage experimentation using human tissues and healthy voluntee

257 Kinetic steady-state modeling predicts and experimentation verifies that mutations affect fitness b

258 Parallel microscale experimentation was used to develop general conditions f

259 Through live imaging and genetic experimentation we demonstrate that PGCs take advantage

260 Through modelling and experimentation we show that this arrangement generates

261 Using mathematical modeling and experimentation, we demonstrate that convergent transcri

262 Through modeling and experimentation, we demonstrate that tasiRNA regulation

263 Using model findings to guide experimentation, we determined that compensatory increas

264 rence and facilitate candidate selection for experimentation, we developed an algorithm called GRACE

265 al system cannot be investigated directly by experimentation, we face the problem of structure identi

266 Using mathematical modeling and experimentation, we show that a second antagonistic "sel

267 Using theoretical modeling and experimentation, we show that current metrics of antipro

268 rcement learning simulations, and behavioral experimentation, we show that the resolution to this ten

269 need for much wider adoption of field-scale experimentation when assessing new technologies and prod

270 iology tools and causality-driven laboratory experimentation will be essential in building new strate

271 More in vivo experimentation will be necessary to fully unravel the m

272 logy approaches and traditional reductionist experimentation will be required for a nuanced understan

273 It is likely that high-throughput experimentation will enable expansion of the synthetic c

274 To permit experimentation with a virus that retained a clinically

275 Experimentation with alcohol typically begins during ado

276 During experimentation with axonemes subjected to mild proteoly

277 In our experimentation with bacterial genomes from the Human Or

278 ucation (MOE) encourages smoke-free schools, experimentation with cigarettes remains a serious proble

279 could be improved, we preformed manipulative experimentation with crop diversity in a countrywide tri

280 ated with increased risk-taking behavior and experimentation with drugs of abuse.

281 shale saprolite sediment in order to permit experimentation with each phase in isolation.

282 kers using a doorstep delivery approach; (2) experimentation with informal and contractual partnershi

283 her than past sporadic behavioural risk (ie, experimentation with injection drug use, unsafe tattooin

284 Further experimentation with isolated adult cardiac myocytes and

285 We combined experimentation with mathematical modeling to elucidate

286 f in vivo imaging experiments and facilitate experimentation with new, bright, photostable fluorescen

287 -stasis HMEC populations can greatly enhance experimentation with normal HMEC.

288 ection with the impedance-time technique and experimentation with novel mesoporous materials to filte

289 constraints on social learning and increased experimentation with point designs.

290 Systems cell biology melds high-throughput experimentation with quantitative analysis and modeling

291 Experimentation with single application of topical bevac

292 The aim of this study was to investigate experimentation with smoking among primary school studen

293 aterials at school predicted a lower risk of experimentation with smoking.

294 smoking on campus predicted a higher risk of experimentation with smoking; the exposure to anti-tobac

295 py on OM in vivo and pave a way for clinical experimentation with the use of high-power laser therapy

296 These findings may inspire further chemical experimentation with tonewood processing for instrument

297 iii) it presents more than a half century of experimentation with various models (e.g., acculturation

298 As with mammals, experimentation with zebrafish constitutes a complicated

299 th-service coverage and health outcomes: (1) experimentation with, and widespread application of, lar

300 Experimentation with, ever, and current smoking, and smo