ライフサイエンスコーパス: exploit

1 he enzyme's susceptibility to metal ions was exploited.

2 Here we exploit a bidecadally resolved (14)C data set obtained f

3 Our study revealed how adenoviruses exploit a capsid-associated small PPxY peptide motif to

4 ese changes, and indicates that splicing may exploit a distinct role of the first domain to change ch

5 Here we successfully exploit a modulation doping scheme to uncover, in conjun

6 e distinct behaviors in different castes, we exploit a natural behavioral plasticity in Harpegnathos

7 e in emission of an appended fluorophore, we exploit a series of host-fluorophore complexes that are

8 Here, we exploit a single-molecule long-read sequencing technique

9 northern black bears, P. abstrusus may have exploited a high-sugar diet in the fall to promote fat a

10 To test this hypothesis, we exploited a mouse model of beta-thalassemia intermedia,

11 We exploited a Near-Infrared Spectroscopy (NIRS) method to

12 We exploited a new method, differential viral accessibility

13 To address this question, we exploited a prion conversion in vitro assay, protein mis

14 leton, and a late-stage large fragment union exploiting a Micalizio alkoxide-directed alkyne-alkene c

15 rtz sources is an essential prerequisite for exploiting a myriad of terahertz applications in imaging

16 oselectivity (up to 96 % ee) was achieved by exploiting a significant matching effect between the chi

17 in high-quality WSe2 monolayers achieved by exploiting a van der Waals heterostructure device platfo

18 ia angularly multiplexed phase-matching that exploits a bio-inspired grating configuration.

19 This implementation exploits a defect, such as a constriction in the magneti

20 The probe design exploits a lysyl residue in EGFP that is essential for c

21 This article exploits a method recently incorporated in the geometric

22 It exploits a nodule compactness heuristic to delineate ind

23 lectivity, and safety could be discovered by exploiting allosterism in plasmin, a protease homologous

24 e artificial aldolase RA95.5-8, for example, exploits amine catalysis to promote mechanistically dive

25 Bacteria exploit an arsenal of antimicrobial peptides and protein

26 The ability to exploit an expanded amino acid alphabet can thus heighte

27 raveling the true potential of plasmonics by exploiting an enhanced native functionality - the majori

28 In this article, exploiting an exact diagonalisation approach, we derive

29 Overall, by exploiting an on-a-chip 22q11.2 DS model, our results su

30 far from tectonic plate boundaries generally exploit ancient faults, but not all intraplate faults ar

31 Efforts to exploit aneuploidy tolerance mechanisms and the BCL9L/ca

32 Tumors exploit angiogenesis, the formation of new blood vessels

33 , indicating that a stimulus-dependent timer exploits arousal to time gaze-shifts.

34 tack, and we suggest that this link could be exploited as a generalizable strategy for identifying th

35 on of cancer tumour and is anticipated to be exploited as a magnificent field in the future.

36 seq to determine whether Brachypodium can be exploited as a model system towards better understanding

37 suggest that catanionic coacervates could be exploited as a novel surfactant-based membrane-free prot

38 We report on how depolarization can be exploited as a strategy to visualize GNR diffusion and d

39 2* and R2 using the CFM could potentially be exploited as a tool to differentiate between normal and

40 diverse crop plants, male-sterility has been exploited as a useful approach for production of hybrid

41 e, we show that geometric frustration can be exploited as a vehicle for conductivity tuning.

42 virally encoded enzymatic function yet to be exploited as an antiviral target.

43 lities of the Internet of Things are not yet exploited as well as they could.

44 behavior across force conditions that may be exploited at a systems level by combining slow and fast

45 ading and manipulating single nuclear spins, exploiting atomic clock transitions for robust qubits an

46 have evolved measures to antagonize or even exploit autophagy mechanisms for the benefit of infectio

47 Inspired by this mechanism, we exploited beta-lactones as putative mycolic acid mimics

48 vel strategies to treat chronic infection by exploiting biofilm dispersal.

49 ince they can optimize the energy density by exploiting both the high permittivity of ceramic fillers

50 oteins, proposed as CW-remodeling mechanisms exploited by Arabidopsis to resist CW degradation upon B

51 smatch repair (MMR) is a conserved mechanism exploited by cells to correct DNA replication errors bot

52 he liver provides a tolerogenic immune niche exploited by several highly prevalent pathogens as well

53 sual monodentate Zn(2+) coordination mode is exploited by sterically bulky HDAC6-selective phenylhydr

54 Exploiting C-H bond activation is difficult, although so

55 by aberrant epigenetic landscapes and often exploit chromatin machinery to activate oncogenic gene e

56 Exploiting co-complexation and trans-metal-trapping stra

57 n-resolved coherent anti-Stokes Raman, which exploits coherent anti-Stokes Raman sensitivity to coupl

58 eories suggest that people understand how to exploit common biases to influence others.

59 This suggests that prions exploit conventional dendritic cells to facilitate their

60 dels are still often used although they only exploit data observed at the end of the experiment.

61 chnique to separate live and dead cells that exploits differences in cellular stiffness.

62 emental composition information, while MS(2) exploits differences in the bond stabilities of a polyme

63 The explore-exploit dilemma occurs anytime we must choose between ex

64 wo different strategies to solve the explore-exploit dilemma: directed exploration, driven by informa

65 l unamplified genomic DNA (gDNA) nanosensor, exploiting dispersion and aggregation characteristics of

66 ich provide the possibility to introduce and exploit distinct functional groups in an otherwise non-f

67 d on a probabilistic framework that not only exploits DNA-binding domains and specificities, but also

68 ow divergent evolution of the ankB allele in exploiting either host farnesylation or the ER retention

69 hich depending on the nature of the peptide, exploits either generation of a signature 69 Da ion from

70 Future work exploiting engineered biomaterials has the potential to

71 loring hierarchical structures remains to be exploited, especially in the creation of new and unconve

72 maximum sensitivity, especially for devices exploiting evanescent spectroscopy.

73 al that patients have marked difficulties to exploit facial social cues elicited by a humanoid robot

74 nected through sea currents to seed the most exploited fisheries and endangered ecosystems.

75 eri Here, we investigated how B. burgdorferi exploits Fn to interact with endothelia under physiologi

76 IV-1 infection may provide unique insight to exploit for novel therapeutic interventions.

77 ider family of complex minerals and could be exploited for a single-step synthesis of van der Waals h

78 wo terminal respiratory oxidases that can be exploited for anti-TB drug development.

79 targetable mechanism that can potentially be exploited for combined therapeutic approaches of embolot

80 ight into its enzymatic function that may be exploited for development of therapeutics for FSHD.

81 ondary electron hyperspectral imaging can be exploited for direct imaging of hierarchical structures

82 These findings can be exploited for eliciting synthetic lethality in metabolic

83 d expand our understanding of viruses and be exploited for epidemiological and medical interventions.

84 induce biosynthetic liabilities that can be exploited for glioma therapy.

85 lead to charge-state fluctuations but can be exploited for long-term data storage or nuclear-spin-bas

86 They were subsequently exploited for methanol electrooxidation in alkaline medi

87 ion and identify target pathways that may be exploited for neoadjuvant therapies.

88 w these diverse regulatory mechanisms can be exploited for novel therapeutic development.

89 ed genes and aberrant splicing, which can be exploited for personalized cancer immunotherapy.

90 addition, avenues are identified that may be exploited for photosynthesis engineering projects in the

91 Up to now, SPR has been poorly exploited for tau detection by immunosensing, due to sen

92 specific locations, which have been recently exploited for the development of aptamer-based biosensor

93 s lining up the antitubercular activity were exploited for the rational design of improved analogues.

94 etween the studied samples should be further exploited for the selection of elite cultivars with spec

95 lts with electron deficient olefins has been exploited for the synthesis of phenylpropanoid natural p

96 exceed the tolerance of cancer cells and be exploited for therapeutic ends.

97 atalytic triad for catalysis, which could be exploited for therapeutics.

98 -dominant neutralizing epitope, which can be exploited for vaccine development.

99 ms, and highlights exciting possibilities to exploit gene and genome transfer in biotechnology and sy

100 binding site selection by a novel mechanism, exploiting gene-specific requirements for chromatin remo

101 stone for future research programs aiming to exploit genetic diversity to improve biotic and abiotic

102 we develop a robust bioinformatics pipeline exploiting Hidden Markov Models for the identification o

103 Here, we exploit histological, transcriptomic, and tomographic me

104 Many intracellular pathogens exploit host secretory trafficking to support their intr

105 These findings suggest that ZAP exploits host CG suppression to identify non-self RNA.

106 Thus, influenza virus exploits host PKCs to regulate RNP assembly, a step requ

107 strategy for implementing such networks that exploits hybridization reactions carried out exclusively

108 ion of substrate-target interaction only, we exploit (i) the narrow resonance of aliphatic protons in

109 ive rise to versatile properties that can be exploited in a range of technologies.

110 gulate function, and such forces may also be exploited in artificial active materials.

111 , allowing the enzyme to be more effectively exploited in biotechnology.

112 strated that this multitasking system can be exploited in breeding barley with tailored amounts of fr

113 halogen atom and an electron donor has been exploited in knowledge-based drug design.

114 'd(5) effect' for Fe(3+) ions that could be exploited in multiferroics.

115 This phenomenon might be exploited in novel prosthetic devices to enhance their c

116 sm, especially during dormancy, which can be exploited in the future to improve winter survival in sw

117 This may be exploited in the future to predict viscosity in numerica

118 perties of graphene-based nanocomposites are exploited in various detection schemes.

119 ur method is based on a hybrid approach that exploits ingredients in both digital and analog quantum

120 By exploiting insight into the spatial arrangement of subdo

121 les can be manipulated in the solid state by exploiting intermolecular interactions.

122 tive chelate-free radiolabeling methods that exploit intrinsic chemical features of nanoparticles.

123 xploring unknown options for information and exploiting known resources for reward.

124 tion of epistatic loci do not systematically exploit linkage disequilibrium.

125 fficient colored perovskite solar cells that exploit localized surface plasmon resonances in ultrathi

126 of salmon sharks indicates they were able to exploit low dissolved oxygen environments (<1-3 ml l(-1)

127 Thus, understanding how viruses evade or exploit macrophage function will provide greater insight

128 bedside biosensors for clinical diagnostics exploiting MIR spectroscopy, to replace laboratory based

129 In order to exploit molecular self-assembly for the bottom-up synthe

130 s of this SNA-based stochastic DNA walker by exploiting movement-triggered cascade signal amplificati

131 d into any WES based processing pipeline and exploits multi-core capabilities.

132 Exploring and exploiting necessarily change how the brain responds to

133 or metastasis by cancers that preferentially exploit nerve tract migration routes.

134 This correlated with the predominantly exploited P sources in the seedling experiment: the N2 f

135 ispersal range increases with trophic level, exploiting pair-approximation techniques to describe the

136 It is well established that viral pathogens exploit PD to spread between cells, but it has more rece

137 beying the modulated excitation paradigm and exploiting phase sensitive detection (PSD).

138 on, linear, deterministic quantum gates that exploit photon polarization and the two-dimensional spat

139 tion process combined with targeting rRNA to exploit phylogenetic differences for sensitive and unamb

140 -photon linear deterministic quantum gate by exploiting polarization along with spatial-parity symmet

141 dentify how migration routes have evolved to exploit predictable atmospheric and oceanic circulation

142 ictor based on structural features and which exploits random forest machine learning, comparing its p

143 onjugates, suggesting broad opportunities to exploit receptors with relatively moderate levels of exp

144 Here we exploit representative whole-genome data sets from six d

145 eys naturally switched between exploring and exploiting rewarding options.

146 To exploit RGC-protective sigma-1 receptor (S1R), we loaded

147 Herein, we describe a strategy that exploits selective alpha-helical PPIs, transferring thes

148 Many biological and synthetic systems exploit self-assembly to generate highly intricate close

149 ed in the last decade due to the interest to exploit shale gas and renewable resources to obtain the

150 ghly mobile animals, allowing populations to exploit spatially or temporally distributed food and spa

151 Cancer cells exploit Spy1 to stimulate proliferation through inapprop

152 The second strategy exploits statistical symmetry for a further reduction of

153 tructural design in materials chemistry have exploited strong directional bonds, whose geometric reli

154 Exploiting such structure-function-toxicity relationship

155 Here, we exploited superresolution approaches combined with clust

156 By appropriately decomposing the input and exploiting symmetries of the Fourier transform we are ab

157 first clinically approved drugs designed to exploit synthetic lethality, a genetic concept proposed

158 Exploiting technical advances toward real-time phase-con

159 crucial for understanding human strategy at exploiting temporally and spatially patchy resources, wi

160 Microbial biophotovoltaic cells exploit the ability of cyanobacteria and microalgae to c

161 ur results suggest that the fish are able to exploit the advantages of multiple senses using vision a

162 Thus, selfish meiotic drivers exploit the asymmetry inherent in female meiosis to bias

163 Here, we exploit the availability of an implementation of five po

164 To mediate repair, we exploit the catalytic domain of Adenosine Deaminase Acti

165 We exploit the close connection between visual motion estim

166 results provide a potential avenue to fully exploit the electro-optical properties of blue phases, w

167 Here, the authors exploit the element and site selectivity of soft X-ray a

168 ct that the results can be useful to further exploit the external perturbation on large core fiber in

169 We exploit the fact that conductivity in semiconductors pro

170 t of labelling, and one possible route is to exploit the fact that MS isotopic patterns reflect the i

171 However, current screening designs may not exploit the full potential of chemical libraries due to

172 nt outcomes, limiting our current ability to exploit the full potential of molecular diagnostics.

173 anded the scope of plasmonic applications to exploit the generated hot carriers.

174 that organisms and cancer are likely able to exploit the genomic robustness properties, due the persi

175 Here we exploit the huge volumetric expansion (up to 3000%) of a

176 Here we exploit the large-scale data analysis techniques to stud

177 Our results reveal that CRISPR-Cas systems exploit the phage life cycle to generate a pattern of sp

178 , the scope of known reactions that directly exploit the polarized reverse-dative sigma-bond of metal

179 In order to fully exploit the potential of SSRs as genetic marker, we deve

180 ogies in recent years, it is now possible to exploit the power of a graphics-processing unit (GPU) fr

181 Here we exploit the presence of sizable quadrupolar and dipolar

182 pecifically, we find that observers learn to exploit the small motion parallax cues provided by head

183 MC-GenomeKey also supports scenarios to exploit the spot instance model of Amazon in combination

184 conclude that plant breeders may be able to exploit the thermal limits of G. pallida by developing p

185 as the derivation of a sustainable method to exploit the whole fruit, both edible and non-edible part

186 We exploited the capacity of single-molecule real-time sequ

187 We exploited the non-universality of Sec to build a proper

188 erlying ESCRT-mediated formation of ILVs, we exploited the rapid, de novo biogenesis of MVEs during t

189 We exploited the reactivity of novel unsaturated electrophi

190 We exploited the safety record of the oral, attenuated S.

191 ored mast cell degranulation in real time by exploiting the capacity of fluorochrome-labeled avidin t

192 determination of the BH-DVCS interference by exploiting the distinct energy dependences of the DVCS a

193 Herein, by exploiting the electrostatic interaction between carbon

194 Moreover, by exploiting the energy dependence of the track diameter,

195 e methodology to tackle this design issue by exploiting the ethyne-bridged (polypyridyl)metal(II) (M;

196 tetrafluoride (beta-NaLnF4) nanocrystals by exploiting the kinetics of the shell growth.

197 d multivalent and multispecific scaffolds by exploiting the modular nature of a repeat protein scaffo

198 o concurrently learn operating the BMI while exploiting the possibility to adapt the available mobili

199 Exploiting the power of Design of Experiments (DoE) and

200 stand the origin of biological complexity by exploiting the power of synthetic chemistry, in conjunct

201 Exploiting the properties of two-dimensional crystals re

202 nt for energy and environmental applications exploiting the redox reactions.

203 roval can conceivably be further enhanced by exploiting the same targeting ligand, conjugated to an i

204 By exploiting the specific fragmentation behavior of pyroph

205 ide an in-depth opinion on the importance of exploiting the tumor microenvironment in cancer therapy,

206 in all-2D photodetectors can be achieved by exploiting the type-II band alignment of vertically stac

207 roles in several neurodegenerative diseases, exploiting the unique structural features and conformati

208 Exploiting the wave-nature of light in its simplest form

209 The cubicon method described here exploits the amphiphilic nature of membrane proteins and

210 It exploits the change in innate milk properties, such as e

211 Instead, our strengthening mechanism exploits the chemical ordering effect that creates backs

212 a probabilistic method, CancerLocator, which exploits the diagnostic potential of cell-free DNA by de

213 The assay exploits the difference in electrochemical signals from

214 Salmonella enterica serovar Typhimurium exploits the host's type I interferon (IFN-I) response t

215 ation and thermal treatment), and thoroughly exploits the nucleation and growth as well as subsequent

216 versatile biosensor platform simultaneously exploits the pH dependency of liquid-gated graphene-base

217 her, our findings suggest that P. aeruginosa exploits the precise spacing of collagen lamellae in the

218 ntly developed helical coil technique, which exploits the transient self-charging of solid targets ir

219 In order to fully exploit their enormous potential in device applications,

220 we aim toward agents that can both build and exploit their own internal models, with minimal human ha

221 ed with a limited ability to therapeutically exploit their weaknesses, have been limiting factors in

222 Here, we have exploited their cosmopolitan status to understand how wi

223 to exclude competing cells from joining and exploiting their groups.

224 h these fleeting intermediates are reviewed, exploiting their superior dienophilic, enophilic, and el

225 2 signaling, possibly offering a junction to exploit therapeutically.Significance: Binding of the tra

226 survival of BRCA2-deficient cells and can be exploited therapeutically through development of specifi

227 tine and illustrate how macrophages might be exploited therapeutically.

228 However, HIV has evolved ways to exploit these cells, facilitating immune evasion and vir

229 logical models, and seeking opportunities to exploit these effects to improve management of insect-bo

230 We exploit these findings to design a chemically synthesize

231 In this work, we instead exploit these integrins as a target for antibody Fc effe

232 onse, autophagy, and cellular metabolism and exploit these pathways to their advantage.

233 twork biology and computational solutions to exploit these phenomena for cancer therapy and biomarker

234 To exploit these properties of TF, a covalent complex betwe

235 eals, allowing the Brachypodium community to exploit these results in future research programs.

236 evelop new diagnostic tools to determine and exploit these variations.

237 Exploiting these capabilities, a detection limit of 800

238 A central limitation to exploiting these compounds, however, has been in identif

239 of the uncaging process, opening the way to exploiting these new coumarin scaffolds as caging groups

240 newer generation of delivery strategies that exploits these endogenous approaches promises to provide

241 RI via a new neuromodulation paradigm, which exploits these power synchronization mechanisms.

242 We exploit this bottleneck to define roles for glial Netrin

243 To exploit this dual concept, we developed agents exerting

244 We exploit this feature by using stimulus responsive polyme

245 7 bound to the DISC1 phosphodegron motif and exploit this information to prove that disruption of the

246 t of human patients, and demonstrates how to exploit this inherent tumor heterogeneity to discover th

247 Future efforts should focus on how to exploit this knowledge to effectively control infections

248 TKs, however, it is unknown whether they can exploit this new signaling mechanism.

249 However, to exploit this potential, novel analytical methods are req

250 We exploited this in vitro Wnt acylation assay to provide d

251 We exploited this natural experiment to better understand t

252 MYD1-72 exploited this relationship, leading to improvements upo

253 We have exploited this system to determine the mechanism of spec

254 Exploiting this feature, a single robot can repeatedly s

255 By exploiting this highly efficient interlayer e-h pair mul

256 Exploiting this isomorphism, a simulated 24-node silicon

257 We exploited three of these data sets-human primary Mvarphi

258 manipulating Cu(I) --> Cu(II) oxidation and exploiting three synergistic roles of boric acid has all

259 al herbal medicines can be reinterpreted and exploited through the lens of modern science.

260 e gene regulatory axis that cancer cells can exploit to circumvent the immune system.

261 also suggest a mechanism that chaperones may exploit to prevent misfolding.

262 groups and C-H bonds of a substrate has been exploited to achieve meta-selective C-H activation by us

263 R targets induces a fitness cost that can be exploited to alter heterogeneous E. faecalis populations

264 and show that this can be pharmacologically exploited to boost insulin secretion.

265 Advances in systems biology can be exploited to comprehensively understand pharmacodynamic

266 exceptional properties of CVD graphene were exploited to construct a highly sensitive and selective

267 a population of multisensory neurons may be exploited to decode self-motion and object motion from t

268 rameters, such as stirring rate, that may be exploited to design other quasicrystal-forming self-asse

269 rvival mechanisms in macrophages, and can be exploited to develop new antimicrobial drugs.

270 oxygen levels and this characteristic can be exploited to develop new diagnostic tools to determine a

271 stem cell (LSC) niche dependencies might be exploited to devise novel therapeutic strategies that ai

272 Our findings suggest that AG can be exploited to diminish drug-resistance in Mtb through red

273 other co-inhibitory receptors that could be exploited to enhance response rates of current immunothe

274 , e-h) pair generation effects, which may be exploited to enhance the photoresponse of nanoscale opto

275 ice isoforms of fibronectin (F8-TNF), can be exploited to eradicate sarcomas in immunocompetent mice.

276 re we show that this structural motif can be exploited to guide the self-assembly of naphthalene diim

277 of either HIPK2 levels or activity could be exploited to impair NRF2-mediated signalling in cancer c

278 A Raman mapping strategy was exploited to increase signal reproducibility and to mini

279 ndrial metabolic vulnerability that might be exploited to kill chemotherapy-resistant acute myeloid l

280 t advances in long-term forecasting could be exploited to markedly improve management of future energ

281 advancements in nanotechnology that could be exploited to overcome the major obstacles in the prevent

282 aces, and suggest novel epitopes that can be exploited to overcome these challenges.

283 xosomes, biomimetic synthetic strategies are exploited to prepare biofunctionalized liposome-like nan

284 the EPO/EPO receptor signaling axis could be exploited to prevent and/or treat T cell-mediated pathol

285 ibitors as antifibrotic agents that could be exploited to promote heart repair following injury.

286 activated complement and in future could be exploited to quantify the severity of myocardial damage

287 how nuclear pore composition changes can be exploited to regulate gene expression at the nuclear per

288 This resource was exploited to study relationships between rDNA locus numb

289 ble silylated nucleophiles to be efficiently exploited to synthesize novel non-proteinogenic alpha-am

290 n these two subsets of CD4(+) T cells can be exploited to target Treg while leaving Tconv intact.

291 Quinone-based compounds have been exploited to treat infectious diseases and cancer, with

292 rtantly, these connections are already being exploited to treat patients with dozens of clinical tria

293 ed methods are powerful tools that are being exploited to unravel new functions with therapeutic adva

294 ar DNA damage response (DDR) which the virus exploits to prepare the nuclear environment for effectiv

295 ternal versus C-terminal carboxylates can be exploited towards obtaining C-terminal functionalization

296 In addition, the explore/exploit trade-off encompasses elements of risk-taking an

297 Targeted cancer therapeutics aim to exploit tumor-specific, genetic vulnerabilities specific

298 erspective's summary features guidelines for exploiting water molecules in drug discovery.

299 ene expression, and this relationship can be exploited while mapping multi-tissue expression quantita

300 Antibody Fab fragments have been exploited with significant success to facilitate the str