ライフサイエンスコーパス: export

1 ds, nectar preparation, jams and jellies, or export.

2 triglyceride-rich lipoprotein biogenesis and export.

3 h in turn results in decreased cellular iron export.

4 oms contributing disproportionally to carbon export.

5 m a gasket around cargo molecules undergoing export.

6 for roughly half of the total organic carbon export.

7 ot disadvantaged; however, 21% died after an export.

8 lu) in these proteins is necessary for their export.

9 of mature transcripts to facilitate nuclear export.

10 ify candidates that function in tRNA nuclear export.

11 are involved in guanidine detoxification and export.

12 xport, cofunctions with Los1 in tRNA nuclear export.

13 me integrity do not result from loss of mRNA export.

14 is involved in basal plant defense and mRNA export.

15 importance of severe rainfall on seasonal SM export.

16 hown to bind to NPC1 and inhibit cholesterol export.

17 n to function in mRNA biogenesis and nuclear export.

18 (6) people and accounts for $31.8 billion in exports.

19 00 deaths) are attributable to international exports.

20 D score of 31 (IQR 27-34) when the liver was exported.

21 related to its function in cargo sorting and export?

22 flushed from soil during water infiltration, exporting 0.01 to 3.9 kg Cr(VI)/km(2)/yr at concentratio

23 uring storms, while the reference watersheds exported 2/3 of their annual water yield during runoff

24 ed ageing period and were greater in chilled export (43d at -1.7 degrees C) than domestic market (5d

25 The mined watersheds exported 7-11% more water than the reference watersheds,

26 A single event 1 week after application exported 96% of SM, which underlined the potential impor

27 s-on the Nansen Ice Shelf in Antarctica that export a large fraction of the ice shelf's meltwater int

28 howing that a Toxoplasma strain deficient in exporting a specific class of effectors is unable to ind

29 mouse model, we show that Abcg4 was able to export Abeta and desmosterol at the BBB level and these

30 irst time that Abcg4 may function in vivo to export Abeta at the BBB, in a process that can be antago

31 nto the secretory pathway, as well as copper export across the plasma membrane.

32 teins underlies the regulation of their mRNA export activities and distinguishes pluripotent from dif

33 ted viral proteins balance strong import and export activities in order to achieve optimal levels of

34 n DEAD-box protein 1 (DDX1) enhances the RNA export activity of Rev through an unknown mechanism.

35 ultiple elements; and a novel, pulsiform RNA export activity regulated by the hepadnaviral posttransc

36 Here, we show that depletion of the nuclear export adaptor SRSF1 prevents neurodegeneration and loco

37 the deletion of residues 1-250 impaired mRNA export and also generated longer lag times when glucose

38 Dry conditions reduce tOM export and can also oxidize wetland soils and release st

39 re the non-linear dynamics that arise during export and determine the ability of passive loading to d

40 onents functionally interact, affecting mRNA export and splicing as well as plant development.

41 f zinc is toxic, therefore dedicated import, export and storage proteins for tight regulation of the

42 y state by phosphorylation-dependent nuclear export and subsequent proteolysis in the cytoplasm.

43 as being required and sufficient for deltaR export and surface delivery in neuronal cells and sugges

44 levels because of SLC7A11-mediated glutamate export and that supplementation of alpha-ketoglutarate,

45 F7, regulators of pre-mRNA splicing, nuclear export and translation-interact with RNA in different ce

46 CYCB transcripts can be exported and translated; however, CDC20 and CCS52B mRNAs

47 o evaluate the effects of both international exports and interprovincial trade on PM2.5 pollution and

48 rphology and trafficking, protein import and export, and other specialized processes.

49 unction in nuclear pre-mRNA processing, mRNA export, and translation.

50 ns play important roles in splicing, nuclear export, and translation.

51 The membrane-embedded part of the flagellar export apparatus contains five essential proteins: FlhA,

52 Here we show that the Legionella export apparatus is localized to the bacterial poles, as

53 ssociated needle complex, the inner membrane export apparatus, and a large cytoplasmic sorting platfo

54 d results can be graphically illustrated and exported as a comprehensive data matrix that contains al

55 different levels of abstraction that can be exported as high quality figures.

56 itional approximately 225 mg Cm(-2)d(-1) was exported as subduction of particle-rich water at the fro

57 and to identify how degradation controls SM export at the catchment scale.

58 membrane localization consistent with auxin export, both preceding the induction of cell cycle- and

59 of importin-alpha and inhibition of nuclear export by leptomycin B resulted in predominant nuclear l

60 rs at the cytosol:membrane interface, before export by the ABC transporter.

61 national food trade, of which two-thirds are exported by Pakistan, the USA and India alone.

62 The nuclear export carrier protein CRM1 recognizes this NES-like seq

63 arge COPII-coated endoplasmic reticulum (ER) export carriers.

64 Here, we used both the export chaperone SecB of Escherichia coli and the tripar

65 it could be a key modulator of a novel Golgi export checkpoint that coordinates GPCR delivery to the

66 rized for its essential role in mRNA nuclear export, cofunctions with Los1 in tRNA nuclear export.

67 periphery, contributes to the generation of export-competent mRNPs and influences gene expression th

68 Transcription-export complex 2 (TREX-2, or THSC) facilitates localizat

69 MOS11 we detected interactions with the mRNA export complex TREX-2 and multiple spliceosomal componen

70 rst-in-class, selective inhibitor of nuclear export compound, which blocks exportin 1 (XPO1) function

71 r, the population will tend to extinction if exports continue.

72 lternatively, disruption of procollagen I ER export could activate the unfolded protein response (UPR

73 foreign trade, emissions embodied in China's exports declined from 2007 to 2012 mainly due to changes

74 using Matrin 3 mutations led to nuclear mRNA export defects of both global mRNA and more specifically

75 andida albicans and good activity against an export-deficient mutant of Escherichia coli.

76 esent TWIMExtract, a data extraction tool to export defined slices of liquid chromatography/ion mobil

77 riptomic, and proteomic approaches to define export-dependent mechanisms regulating the levels of ESX

78 tant NS1 polypeptides unable to promote mRNA export did neither.

79 DOC production and export display a pronounced peak in the oligotrophic sub

80 C2A kinase domain to the TGN-induced deltaR export downstream of NGF.

81 pathway for the selective regulation of mRNA export during stress via retrotransposon activation.

82 riking behaviors include "burst" RNA nuclear export dynamics regulated by HIV-1's Rev response elemen

83 sicle budding reaction, that mutant TREM2 is exported efficiently from the ER.

84 extent similar to events occurring with the export element (PEXEL) found in malaria effector protein

85 t many roles in cells, participating in mRNA export, embryonic development, and apoptosis.

86 ries became the major destination of China's export emissions.

87 de shRNA-based screen, we identified nuclear export factor 3 (NXF3) as a transporter that alters the

88 increasing the interaction with the nuclear export factor CRM1.

89 ive in the THO component TEX1 or in the mRNA export factor MOS11 (orthologue of human CIP29) are mild

90 ition to the RNA helicase UAP56 and the mRNA export factors ALY2-4 and MOS11 we detected interactions

91 ts revealed not only a critical role of mRNA-export factors in transcriptional anti-silencing but als

92 moters, and reflect levels of processing and export factors on the encoded transcript.

93 ng it to enzymes, for storage (ferritin) and export (ferroportin).

94 achieve a given export rate and accelerates export for a given concentration of Suc in the mesophyll

95 that Mex67-Mtr2 functions in primary nuclear export for a subset of yeast tRNAs.

96 acetylation of FOXO3a results in its nuclear export for degradation and consequent down-regulation of

97 proteins, which are involved in cholesterol export from LEs, and the lysosome-associated membrane pr

98 e, another triazole, also blocks cholesterol export from lysosomes.

99 5.5 Tmol year(-1), similar to the estimated export from palaeo rivers.

100 te that BASS6 and PLGG1 partner in glycolate export from the chloroplast, whereas PLGG1 alone account

101 In contrast, it did not affect protein export from the ER lumen or from endosomes into the cyto

102 ant kinase activity of Kit(mut) prevents its export from the Golgi to the PM.

103 river-transported microbiota, and that cell export from the GrIS is dependent on discharge.

104 body level, dietary iron absorption and iron export from the tissues into the plasma are regulated by

105 agosomal membrane protein that controls iron export from vacuoles and inhibits Salmonella growth in m

106 ), carbon dioxide (CO2 ), and methane (CH4 ) exported from a boreal peatland catchment coupled with (

107 ination of the abundance and lability of DOC exported from land to water and produced by photochemica

108 ary receivers of nutrient and organic carbon exported from terrestrial ecosystems and are profoundly

109 ctions, stored within cytosolic ferritin, or exported from the cell via FPN1.

110 intracellular pockets that are subsequently exported from the cell where a nucleation process leads

111 Acyl groups released by PLIP1 are exported from the chloroplast, reincorporated into phosp

112 posed a model where subcomplexes of vRNA are exported from the nucleus and assembled en route to the

113 We found that Cyclin B1 must be exported from the nucleus for the cell to prevent premat

114 How repeat transcripts get exported from the nucleus is unknown.

115 Once exported from the nucleus, menin was ubiquitinated and d

116 Eukaryotic transfer RNAs (tRNAs) are exported from the nucleus, their site of synthesis, to t

117 oth the anterior and posterior surfaces were exported from the Pentacam HR software.

118 apparently reflected variable losses of MeHg exported from upstream wetlands due to demethylation, ab

119 m xc(-)), which plays an antioxidant role by exporting glutamate for cystine.

120 s organoleptic and bioactive properties, its exports have significantly increased.

121 Of the 61 exported hearts, 43 were turned down in region for donor

122 rol into the intestinal lumen via the sterol-exporting heterodimer adenosine triphosphate binding cas

123 ar export machinery to promote their nuclear export.IMPORTANCE Influenza A virus is a major pathogen

124 SecB chaperones assist protein export in bacteria.

125 nd its function was essential for fatty acid export in cells lacking the acyl-CoA synthetases Faa1 an

126 lance of new production and sinking particle export in coastal upwelling ecosystems.

127 c program and regulates lipid absorption and export in intestinal epithelial cells.

128 hesis by revealing a disrupted CD19 membrane export in the post-endoplasmic reticulum compartment as

129 l elements are important for growth and mRNA export in vivo.

130 High P exports in storm drainage networks and yard waste result

131 g should occlude Fpn and interfere with iron export independently of endocytosis.

132 ay serve as a key homeostatic control for Cu export into the circulation.

133 valent metal-ion transporter 1 (DMT1) and is exported into the circulation via ferroportin 1 (FPN1).

134 In eukaryotes, most RNA molecules are exported into the cytoplasm after transcription.

135 ways but is compromised when nuclear protein export is blocked.

136 As tRNA nuclear export is essential, we previously interrogated the budd

137 These results indicate that efficient ER export is not sufficient to enable normal cell-surface e

138 t the effective regime of convection-limited export is predominant in plants with large transport res

139 This mode of protein export is termed type-III secretion (T3S).

140 TREX (TRanscription-EXport) is a multiprotein complex that plays a central r

141 enic amines in Canadian pork for the chilled export Japanese market were not in sufficiently high con

142 it is unclear how they are recruited to the export machinery or how the intron-containing but unspli

143 between viral mRNAs and the cellular nuclear export machinery to promote their nuclear export.IMPORTA

144 he viral mRNAs and the cellular mRNA nuclear export machinery.

145 rter that uses energy from ATP hydrolysis to export many structurally dissimilar hydrophobic and amph

146 t into the unique molecular architecture and export mechanism of the Pel apparatus, a widespread exop

147 ng concerns the vertical distribution of the exported meltwater.

148 er proline, and they actively synthesize and export metabolic intermediates to the apical side to nou

149 n CRM1 recognizes this NES-like sequence and exports misfolded SOD1 to the cytoplasm.

150 Glacier-fed streams also export more acid-soluble iron (27.0-18,500 kg km(-2) a(-

151 onditions by remaining active for longer and exporting more water.

152 gest producer of crystal sugar in the world, exporting much of its production to the soft drinks indu

153 also showed that desmosterol antagonized the export of Abeta, presumably as both bind at the sterol-b

154 ng differentiation, coinciding with enhanced export of adipogenic RNAs.

155 ight alternative strategies for handling and export of amyloid protein sequences.Gram-negative bacter

156 pifithrin-mu such that endoplasmic reticulum export of and radioligand binding and substrate uptake b

157 AP-4 promotes signal-mediated export of ATG9A from the trans-Golgi network to the peri

158 t the porin channels are associated with the export of bacterial cell wall lipids outside of vacuole.

159 yr(-1)), together with elevated terrestrial export of bicarbonate (HCO3(-); 3.6 mueq L(-1) yr(-1)).

160 function for TM6SF2 in the lipidation and/or export of both hepatically and intestinally derived trig

161 Export of both mRNAs is dependent on the cellular NXF1/T

162 to generate a transport intermediate for the export of bulky collagens.

163 The aquatic export of C from boreal peatlands is recognized as both

164 of SRSF1 triggers the NXF1-dependent nuclear export of C9ORF72 transcripts retaining expanded hexanuc

165 Conversely, stimulating the export of calcium from mitochondria was also neuroprotec

166 nes to generate a mega-transport carrier for export of collagens and apolipoproteins from the ER.

167 an Province, China led to the collection and export of countless such fossils.

168 Of importance, PI3K C2A expression promotes export of endogenous deltaR in primary trigeminal gangli

169 s of protein-bound Cbl followed by lysosomal export of free Cbl to the cytosol and further processing

170 Calcium-dependent nuclear export of histone deacetylase 1 (HDAC1) was shown previo

171 the most critical steps in this process, the export of internalized antigen to the cytosol, has been

172 tial viral Rev protein that mediates nuclear export of intron-bearing late-stage viral mRNAs.

173 rtin-1 (XPO1) is the key mediator of nuclear export of many tumor suppressor proteins and is overexpr

174 the Negro Basin probably due to the variable export of MeHg from poorly drained soils that are abunda

175 provide insight into the factors controlling export of MeHg to the Amazon system.

176 Gastrin-induced nuclear export of menin via cholecystokinin B receptor (CCKBR)-m

177 ination of synthesis, processing and nuclear export of mRNAs.

178 EX complex (TREX) plays key roles in nuclear export of mRNAs.

179 Bcp1 has been shown to be necessary for the export of Mss4, a phosphatidylinositol 4-phosphate 5-kin

180 To determine the winter export of N and P, we monitored stormwater outflow in a

181 hoinositide-3 kinase (PI3K) activity blocked export of newly synthesized deltaR from the Golgi and de

182 n the only exporter known to execute nuclear export of newly transcribed intron-containing pre-tRNAs.

183 rate of postinduction IkappaBalpha-mediated export of NFkappaB from the nucleus decreased markedly.

184 Thus, TGF-beta-induced nuclear export of NR4A1 in TNBC cells plays an essential role in

185 with NXF1 specifically inhibits the nuclear export of pathological C9ORF72 transcripts, the producti

186 f proteins involved in the transcription and export of piRNA precursors from components required for

187 s is a multiprotein complex dedicated to the export of several virulence factors during host infectio

188 how that PB components assist in the nuclear export of Ssd1and subsequent targeting of Ssd1 to PB sit

189 negative bacteria that mediate the import or export of substrates and/or extrusion of type IV pili.

190 n of NR4A1 nuclear export results in nuclear export of TGF-beta-induced beta-catenin, which then unde

191 Selection and export of the effectors is controlled by a set of solubl

192 cancer (TNBC) cells is dependent on nuclear export of the orphan receptor NR4A1, which plays a role

193 rived NR4A1 antagonists that inhibit nuclear export of the receptor and thereby block TGF-beta-induce

194 n phosphorylates NR4A1, resulting in nuclear export of the receptor.

195 of viral mRNAs, it also promotes the nuclear export of the viral late gene mRNAs by acting as an adap

196 nd BCLAF1 in the selective mRNA splicing and export of transcripts encoding key DDR proteins, includi

197 BASS6 and PLGG1 therefore balance the export of two glycolate molecules with the import of one

198 calized mobilization of U without leading to export of U from the reducing sediments when ample organ

199 endogenous cellular process for the nuclear export of very large RNPs and protein aggregates.

200 ystem: (i) waste input into the system, (ii) export of waste (iii) gaseous emissions from waste treat

201 ZntB has been proposed to play a role in the export of zinc, but the transport mechanism of ZntB is p

202 hat the formation of O3 was impacted by both exports of plumes upwind and local photochemical reactio

203 The mined watersheds exported only 1/3 of their streamflow during storms, wh

204 (with no lysine [K] 1) in the mammalian mRNA export pathway even though it was previously established

205 rtin 3 import pathways and the Crm1-mediated export pathway.

206 ucleotides into the mitochondrial matrix and export phosphate to the cytosol.

207 pressed on the plasma membrane, and actively exports phospholipid complexes from the cytoplasmic to t

208 ity of the spatial variability in the carbon export potential (76-92%).

209 otic plankton community structure and carbon export potential at the Western Antarctica Peninsula (WA

210 network analysis that ecosystems with lower export potential have more tightly coupled communities.

211 is known about the function of Prp40 in the export process.

212 C is estimated to account for 20% of global export production, but the degree to which this varies r

213 This exported production is further rarefied by microbial bre

214 with long cytoplasmic fibrils, likely to be exported progeny RNA.

215 e 3' regions of the mRNA in vivo, identifies export-promoting ALYREF-binding motifs, and reveals CstF

216 ble, first-in-class inhibitor of the nuclear export protein XPO1, in this phase 1 trial to assess saf

217 inexor, a selective inhibitor of the nuclear export protein XPO1.

218 RNA pol II degradation factor Def1, the mRNA export protein Yra1 and the HECT E3 ligase Tom1.

219 e introduce Plasmodium falciparum gametocyte exported protein-5 (PfGEXP5) transcript analysis as an i

220 export uses it to complement its own nuclear export proteins (a site not targeted by current therapy)

221 Bacteria export proteins across membranes using a range of transp

222 H1, RhopH3, the erythrocyte cytoskeleton and exported proteins involved in host cell remodeling.

223 atic cholestasis-1 (FIC1), 18 with bile salt export pump (BSEP) disease, and 4 others with low gamma-

224 mall heterodimer partner (SHP) and bile salt export pump (BSEP).

225 The bile salt export pump (BSEP/ABCB11) transports bile salts from hep

226 sed minimally of a Cu sensor (CueR) and a Cu export pump (CopA).

227 Cs, resulting in the expression of bile salt export pump.

228 wth, indicating R. solanacearum produced and exported putrescine to xylem sap.

229 The instability promotes vigorous lateral export, rapid dilution by turbulent mixing, and finally

230 tent in the leaf required to achieve a given export rate and accelerates export for a given concentra

231 and non-PHS-IR donors, as well as to compare export rates and variation in utilization.

232 reasonable parameter values, but even higher export rates can be accessed in scenarios in which polym

233 Furthermore, all PHS-IR organs had higher export rates than non-PHS-IR organs.

234 gion maintenance 1 (CRM1), the major nuclear export receptor for proteins.

235 challenge the current paradigm that nuclear export regulates the proteolysis of FOXO3A/4 tumour supp

236 f a stable periplasmic conformer involves an export-related, folding pathway not present in E. coli.

237 Inhibition of NR4A1 nuclear export results in nuclear export of TGF-beta-induced bet

238 ze of reserves needed to meet the 30% larval export rule are unlikely to compromise the protection of

239 hydrophobic residues (including the nuclear export sequence), providing a rationale for the increase

240 us due to its nuclear localization (NLS) and export sequences (NES).

241 Furthermore, we identified a nuclear export signal (NES) at the N terminus (AAs 176-192) that

242 clear localization signal (bNLS) and nuclear export signal (NES), as well as to a fluorescent protein

243 (wt) SOD1 exposes a normally buried nuclear export signal (NES)-like sequence.

244 r localization signal and C-terminal nuclear export signal (NES).

245 is highly conserved within the first nuclear export signal consensus sequence identified in Saccharom

246 The nuclear export signal of AR (NES(AR)) has an important role in A

247 cine-rich stretch, which resembles a nuclear export signal, and could be inactivated by site-directed

248 e cytoplasm employing a heterologous nuclear export signal, it is expressed at very low levels and is

249 1 is a critical novel host factor of nuclear export signaling whereby the IAV nuclear export uses it

250 Prp40 possesses two leucine-rich nuclear export signals, but little is known about the function o

251 ers forming on ice shelves could potentially export stored meltwater and prevent its destructive effe

252 ter from Catharanthus roseus, CrNPF2.9, that exports strictosidine, the central intermediate of this

253 Exported substrates are chaperone-delivered to the trans

254 s rely on differences in osmotic pressure to export sugars from regions of synthesis (mature leaves)

255 HDAC4 at Ser(246) and preventing its nuclear export that leads to cytoplasmic degradation of the deac

256 Photoreceptors then export the lactate as fuel for the retinal pigment epith

257 ensures that the transporter is available to export the newly synthesized peptides, preventing toxic-

258 erminal NMB0419 signal peptide, predicted to export the protein beyond the cytoplasmic membrane, resu

259 In addition, we exported the results after "manual refinement" to correc

260 The ABC transporter McjD exports the antibacterial peptide MccJ25 in Escherichia

261 rs can modify the simulation experiments and export them in standard formats.

262 used to directly modulate nuclear import and export, thereby regulating the reporter's distribution b

263 Fabric software was extended to generate and export this nucleus model to a text file with a specific

264 usive loading from the source and convective export through the phloem.

265 vage at positions G17/G18 and G35/A36 during export through the type I secretion system.

266 The majority are secreted proteins, exported through the classical endoplasmic reticulum (ER

267 and PABPN1-mediated coupling of mRNA nuclear export to 3' processing.

268 biogeochemical and ecological impacts of DOM export to downstream environments.

269 large resilience of the source of aquatic C export to forecasted hydroclimatic changes.

270 tors for dissolved iron and thus enhance its export to the coastal ocean.

271 This in turn facilitates mRNA export to the cytoplasm.

272 inished enzymatic activity and prevention of export to the Golgi due to prolonged association with th

273 ce local vegetation, soil development and OM export to the lake sediments.

274 Abundances of freshwater diatom frustules exported to Eel Canyon sediment from 1988 to 2001 were p

275 These are then copied as RNA and exported to manufacture new proteins.

276 be packaged into exosomes and potentially be exported to neighboring uninfected cells, leading to inc

277 From here, ST8 was exported to North America in the early 20th century and

278 3 to June 2015, we identified 1768 DD livers exported to regional candidates with MELD scores >/=35 w

279 most heavily affected, but Ebola cases were exported to several other African and European countries

280 Cr(VI)) is generated in serpentine soils and exported to surface and groundwaters at levels above hea

281 ine or from (13)C glucose, is preferentially exported to the apical side and is taken up by the retin

282 l, is synthesized in the Golgi apparatus and exported to the cell wall in a highly methylesterified f

283 polymerase in the cell nucleus before being exported to the cytoplasm for translation.

284 ogenesis in eukaryotes, nascent subunits are exported to the cytoplasm in a functionally inactive sta

285 iral RNAs transcribed in the cell nucleus be exported to the cytoplasm without being spliced.

286 RNAs exceed RBP sequestration capacity, are exported to the cytoplasm, and undergo RAN translation.

287 a large number of parasite proteins that are exported to the host cell, and is also the underlying ca

288 These proteins then traffic via an export translocon to the host membrane, where they form

289 entered on proteins in the TRanscription and EXport (TREX) complex, known to function in mRNA biogene

290 ear export signaling whereby the IAV nuclear export uses it to complement its own nuclear export prot

291 ATP-binding cassette (ABC) transporters help export various substrates across the cell membrane and s

292 The underlying reasons for export versus retention remain unclear.

293 For example, 28.7% of PHS-IR kidneys were exported versus 19.7% of non-PHS-IR kidneys.

294 e injectisomes of gram-negative pathogens to export virulence factors into host cells.

295 We find that active drainage has exported water off the ice surface through waterfalls an

296 s of Paf1 on Pol2 promote transcript nuclear export, whereas low levels reflect nuclear retention.

297 d, Ehhadh, Hsd10 and Acaa2, and blunted VLDL export with decreased expression of Mttp and its product

298 We calculate 78% of snowpack Hg was exported with snowmelt runoff in 2008 and 41% in 2009.

299 In three cases, OPOs exchanged regional exports within a 24-h window.

300 ding cassette (ABC) transporter TarGH, which exports WTA precursors to the cell surface for attachmen