ライフサイエンスコーパス: export pathway

1 rtin 3 import pathways and the Crm1-mediated export pathway.

2 ins out of the nucleus via the CRM1-mediated export pathway.

3 function in a Los1p-independent tRNA nuclear export pathway.

4 exporter or an adapter in this tRNA nuclear export pathway.

5 ly involved in the CRM1-mediated Rev nuclear export pathway.

6 fficulty in capturing "snapshots" during the export pathway.

7 he SecA component of the bacterium's protein export pathway.

8 orted viral mRNAs to access the TAP-mediated export pathway.

9 -7 is exerted through a CRM-1-dependent mRNA export pathway.

10 in component, one involving the nonclassical export pathway.

11 NXT1 in the context of the Tap-dependent RNA export pathway.

12 of NXT1 in the context of the Crm1-dependent export pathway.

13 omain and a competent Crm1-dependent nuclear export pathway.

14 ticoid receptor (GR) and to characterize the export pathway.

15 g 10 that have counterparts in the flagellar export pathway.

16 peration of this major new bacterial protein export pathway.

17 SV DR element uses a novel nucleocytoplasmic export pathway.

18 eins are general components of the flagellar export pathway.

19 P2 emerges as a key component of the nuclear export pathway.

20 ev ARM and the successive Rev-dependent mRNA export pathway.

21 Exd is exported by a CRM1/exportin1-related export pathway.

22 er of a protein to the next component in the export pathway.

23 ssion of RNAs dependent on the cellular mRNA export pathway.

24 t prefolded proteins to an alternate protein export pathway.

25 protein export, which proceeds by a type III export pathway.

26 1p is a carrier for the NES-mediated protein export pathway.

27 ences share a common specialization in their export pathway.

28 P/NXF, providing a link to the cellular mRNA export pathway.

29 ows viral mRNAs to access a cellular protein export pathway.

30 eriplasm of Escherichia coli via the general export pathway.

31 15 proteases were more effective against the export pathway.

32 of parasite proteins via a dedicated protein export pathway.

33 t of the endoplasmic reticulum-Golgi protein export pathway.

34 ds to the mRNP at several stages of the mRNA export pathway.

35 y for secretion and a downstream step in the export pathway.

36 ed from cells by a specialized, nonclassical export pathway.

37 nism of this new type of specialized protein export pathway.

38 on in the proper function of the Tat protein export pathway.

39 vered to the growing flagellum by a type III export pathway.

40 ort of nsP2 is mediated via the CRM1 nuclear export pathway.

41 by inhibiting the Exportin1-mediated nuclear export pathway.

42 that participated in CRM1-dependent nuclear export pathway.

43 mponent of the general Sec-dependent protein export pathway.

44 on is sufficient for mediating the Gle1-mRNA export pathway.

45 egion maintenance-1 (CRM1)-dependent nuclear export pathway.

46 instead, are secreted through the flagellar export pathway.

47 he cell periphery via the classical Golgi/ER export pathway.

48 import receptor and a competent CRM1-nuclear export pathway.

49 ing that native Tax utilizes another nuclear export pathway.

50 that DsbAss directs thioredoxin 1 to the SRP export pathway.

51 the export factor Aly/REF to access the TAP export pathway.

52 iring Mob2p, Cbk1p, and a functional nuclear export pathway.

53 nuclear RNA export, they do so via unrelated export pathways.

54 r import and previously unrecognized nuclear export pathways.

55 eoporin functions and specialized import and export pathways.

56 involved at a vital juncture point in their export pathways.

57 of Xpo1p in at least one of several nuclear export pathways.

58 st cell requirements of these two viral mRNA export pathways.

59 as GR and hnRNP A1 that use distinct nuclear export pathways.

60 to be an essential component of multiple RNA export pathways.

61 t alternately exposes sugar import and sugar export pathways.

62 de a key link between the nuclear import and export pathways.

63 imultaneously exposes sugar import and sugar export pathways.

64 ral RNA to the cellular CRM1 or NXF1 nuclear export pathways.

65 ess splicing-dependent cellular mRNA nuclear export pathways.

66 ent tissues via at least 2 SID-1 independent export pathways.

67 plays a functional role in multiple nuclear export pathways.

68 tion of MNK1 suppresses endogenous HDM2 mRNA export pathways.

69 ncreased diversification of these organisms' export pathways.

70 trols the entry of virtually all proteins to export pathways.

71 e evolutionary divergence of eukaryotic mRNA export pathways.

72 ting these enzymes are secreted by different export pathways.

73 that disrupt different Ran-dependent nuclear export pathways.

74 The nuclear export pathway accessed by NTD is insensitive to leptomy

75 rev-mediated transport, suggesting that the export pathways accessed by the adenoviral and retrovira

76 Furthermore, choice of proper export pathway affects tra-2 translational control.

77 These viruses interfere with import-export pathways, allowing for the cytoplasmic accumulati

78 east one-and perhaps several-additional tRNA export pathways also exist.

79 RNA helicase which functions in the CRM1 RNA export pathway analogously to the postulated role for Db

80 suggested that Rae1 is involved in the mRNA export pathway and Bub3 in the mitotic checkpoint.

81 spatio-temporal aspects of this nonclassical export pathway and demonstrate that heat shock stimulate

82 sm of leukemogenesis mediated by the nuclear export pathway and support further investigation of the

83 and budding are regulated by the RNA nuclear export pathway and that alternative cellular pathways ca

84 Rev and PKI act through an identical nuclear export pathway and that Rev, rather than using a dedicat

85 In Pseudomonas aeruginosa this export pathway and type IV pilus biogenesis are dependen

86 smic RNP complexes, providing a link between export pathways and cytoplasmic fate.

87 ideless proteins occurs through nonclassical export pathways and the release of fibroblast growth fac

88 Tax translocation required the CRM1 nuclear export pathway, and a transient interaction between Tax

89 Components of this unconventional export pathway are highly conserved, suggesting that thi

90 e flagellar apparatus and associated protein export pathway are well conserved in evolution.

91 pendent on the presence of an intact nuclear export pathway as c-Jun is stabilized and localized to t

92 sugar sensor to regulate an inducible sugar export pathway as leaves develop under high light condit

93 yeast Gle1 involved in the same poly(A) mRNA export pathway as Nup159, also result in seed abortion.

94 ant and reveals a role for the Crm1-mediated export pathway at a late step in viral infection.

95 out of the nucleus through the CRM1 nuclear export pathway, based on observations that treatment of

96 ascent chains that monitor different protein export pathways by a shared molecular mechanism.

97 agella at different stages of assembly, each export pathway can discriminate and sort unchaperoned ea

98 capacities of the folding, degradation, and export pathways, collectively dictate an adaptable stand

99 Type III secretion (T3S), a protein export pathway common to Gram-negative pathogens, compri

100 mplicate IPMK in a transcript-selective mRNA export pathway controlled by phosphoinositide turnover t

101 53, suggesting that the Tap and CRM1 nuclear export pathways converge at the cytoplasmic periphery of

102 The second acid-export pathway does not require extracellular anions or

103 rge numbers of PE/PPE proteins via the major export pathway, ESX-5.

104 (with no lysine [K] 1) in the mammalian mRNA export pathway even though it was previously established

105 ifferentially regulated, hnRNP-specific mRNA export pathways exist.

106 Notably, protein secretion through the curli export pathway facilitates acquisition of the amyloid fo

107 smic membrane of many bacteria, is a general export pathway for folded proteins.

108 ar envelope budding is an endogenous nuclear export pathway for large RNP granules.

109 results imply remarkable flexibility in the export pathway for the 60S subunit and help explain how

110 2 complex reflects a defect in the bona fide export pathway for the 60S subunit.

111 ve inhibitor of rev export, arguing that the export pathways for hdm2 and rev are either overlapping

112 Two distinct nuclear export pathways for retroviral mRNA have been described:

113 ngly suggest that there are multiple nuclear export pathways for these small RNAs in Arabidopsis.

114 e an alternative to the Sec (general protein export) pathway for translocation across the inner membr

115 endent, suggesting that RSV uses a different export pathway from that of HIV-1 and other complex retr

116 NA to Tap, suggesting it may use a different export pathway from that of the simian retroviruses.

117 These are the general export pathway (GEP), a twin-arginine translocase (TAT)

118 spective, and the definitions of the general export pathway (GEP), the main terminal branch (MTB) of

119 The Sec-dependent protein export pathway has been well characterized in Escherichi

120 , and provides insight into a divergent mRNA export pathway in apicomplexans.

121 hus allowing direct visualization of the Rev export pathway in living cells.

122 o determine the functional nature of the Tat export pathway in mycobacteria.

123 lved to take advantage of a cellular protein export pathway in order to allow the nucleocytoplasmic t

124 irecting messages into a CRM1-dependent mRNA export pathway in somatic mammalian cells.

125 We identify a dedicated ISC/export pathway in which augmenter of liver regeneration,

126 ssibility that TRalpha follows a cooperative export pathway in which both calreticulin and CRM1 play

127 on assay to show that there are two cytokine export pathways in T helper cells.

128 cted cells, implicating altered lipid import/export pathways in these cells.

129 d in vivo with other components of the CRM 1 export pathway, including the small GTPase Ran and the n

130 Further progress on the export pathway, including the terminal step of Crm1 and

131 , which inhibits the Crm1- dependent nuclear export pathway, induces an accumulation of epsin 1 in th

132 and CucA have signal peptides for different export pathways into the periplasm, Tat and Sec respecti

133 may access the same constitutive RNA nuclear export pathway involving RHA, Tap and Sam68, even though

134 Saturation of tRNA export pathway is a possible explanation of this phenome

135 it is likely that this constitutive export pathway is also used by cellular mRNA, but at a d

136 This dedicated export pathway is comprised of seven components (SecA2,

137 subtilis can export Ply, suggesting that the export pathway is conserved.

138 This RNA export pathway is CRM1 dependent and can be blocked by t

139 This androgen receptor export pathway is dependent on ATP hydrolysis and is enh

140 We show that this protein export pathway is highly conserved by demonstrating that

141 that Rev, rather than using a dedicated RNA export pathway, is instead acting as an adaptor that all

142 ially requires a Sub2-mediated mRNP assembly/export pathway linked to transcription via Rlr1.

143 These findings suggest that the CRM1 nuclear export pathway may be important in the functional regula

144 Thus the rev nuclear export pathway may be used to regulate an oncogene produ

145 Atypical nuclear export pathways may thus exist that regulate the compart

146 B, an inhibitor of CRM-1, indicates that the export pathways mediated by Rev and Sam68 are distinct.

147 xiliary protein in the Sec-dependent protein export pathway of Escherichia coli.

148 mbrane protein, gates the type III flagellar export pathway of Salmonella.

149 dressed the relationship between the nuclear export pathway of SNV RU5-reporter RNA and translational

150 ed S(0) in soils, vegetation, and hydrologic export pathways of Napa Valley, CA vineyards, documentin

151 te that the ER-associated degradation (ERAD) export pathway operates in the phagosomes of dendritic c

152 aminoacylation and Los1p operate in the same export pathway or there are more than two pathways for t

153 sport of bacterial proteins across a non-Sec export pathway possess an N domain RRXFLK consensus moti

154 that protein secretion via this specialized export pathway promotes acquisition of the amyloid fold

155 e, suggesting the presence of redundant tRNA export pathway(s) in Arabidopsis.

156 Nup153 antibodies also block the NES protein export pathway, specifically the export of the HIV Rev p

157 Prediction of export pathway specificity in prokaryotes is a challengi

158 the proinflammatory cytokine IL-1beta via an export pathway that depends on Atg5, inflammasome, at le

159 directs unspliced viral RNAs into a nuclear export pathway that is congruent with the pathway used b

160 indicate that RU5 gag RNA accesses a nuclear export pathway that is distinct from the LMB-inhibited l

161 irects SNV RU5-containing RNAs to a distinct export pathway that is not inhibited by LMB and programs

162 CRT defines a new export pathway that may regulate the transcriptional act

163 Here, we identify a novel host cell effector export pathway that requires the Golgi-resident aspartyl

164 e the existence of ICP27-independent nuclear export pathways that are accessible to many viral transc

165 n the requirement for Npl3p defines the mRNA export pathway, the requirement for Rip1p defines a path

166 tors associated with the two recognized mRNA export pathways, these results suggest that RTE function

167 Thus, NXT1 regulates the Crm1-dependent export pathway through its direct interaction with Ran-G

168 the function of multiple important bacterial export pathways, through direct allosteric control of ex

169 ponse Element (RRE) through the Crm1 nuclear export pathway to the cytoplasm where viral proteins are

170 HIV-1 requires a specialized nuclear export pathway to transport unspliced and partially spli

171 These data show that the nuclear export pathway used by steroid hormone receptors such as

172 t, suggesting that the ability to follow the export pathway used by TRalpha has been lost by the onco

173 nsferase pull-down assays to investigate the export pathway used by TRalpha.

174 nd demonstrate that the MPMV CTE nuclear RNA export pathway uses a distinct, Crm1-independent mechani

175 o reveal which steps, if any, in the nuclear export pathway utilized by steroid receptors require ATP

176 go nucleocytoplasmic shuttling when the CRM1 export pathway was blocked by LMB treatment, suggesting

177 ag rapidly became intranuclear when the CRM1 export pathway was blocked, implying that most if not al

178 Finally, the export pathway was further defined by the ability of spe

179 hat use other karyopherin-mediated import or export pathways was not affected in a kap119Delta strain

180 characterize elements of the vertebrate mRNA export pathway, we identified a human homologue of yeast

181 presented indicating that nuclear import and export pathways were not adversely affected by vaccinia

182 Rev and RanBP1 compete for the same nuclear export pathway, whereas Rev- and the CTE-mediated pathwa

183 tling protein that utilizes the CRM1 nuclear export pathway, while HIV-1 Gag is excluded from the nuc

184 he viral proteins utilize the CRM1-dependent export pathway, while the cellular factors generally fun

185 scovered that inhibition of the CRM1 nuclear export pathway with leptomycin B causes FIV Gag but not

186 mplex and widespread gram-negative bacterial export pathway with the capacity to translocate protein

187 translocation) system is a bacterial protein export pathway with the remarkable ability to transport

188 We propose the existence of multiple mRNA export pathways, with export of Nab2p-associated mRNAs d