ライフサイエンスコーパス: exposome

1 s can be maximized in research to define the exposome.

2 of tools have been identified to measure the exposome.

3 robial and chemical components of the indoor exposome.

4 d as part of a comprehensive analysis of the exposome.

5 isms, and to improve understanding about the exposome.

6 pond to such exposures should be part of the exposome.

7 cal impact of exposure to the concept of the exposome.

8 igned to capture information about the toxic exposome.

9 that can be used to characterize individual exposomes.

10 blood specimens can be used to characterize exposomes.

11 The exposome and biology are interactive-changes in biology

12 need to define a "healthy" built environment exposome and how to control it.

13 As exposome and interactome vary from person to person and

14 the factors that shape the built environment exposome and its influence on human wellness and disease

15 ofiling technique to identify changes in the exposome and metabolome of roach (Rutilus rutilus) expos

16 uthors describe the biological impact of the exposome and outline many of the targets and processes t

17 the genome, with the interaction between the exposome and the genome ultimately determining one's phe

18 th critical in studies aiming to capture the exposome and to make recommendations on how to transitio

19 To explore the "blood exposome" and its connection to disease, we sought human

20 the totality of these exposures, i.e., the "exposome", and their specific biological effects constit

21 We aimed to highlight exposome approaches for investigating the potential infl

22 her address the effect of the metagenome and exposome as key modifiers of immune-system aging and dis

23 Exposome-based approaches have the potential to enable n

24 study measured part of the in-hive pesticide exposome by analyzing residues from live in-hive bees, s

25 Both the epigenome and exposome change with age.

26 d to develop analytical tools appropriate to exposome data.

27 The METLIN Exposome database has been redesigned to help identify e

28 to describe the correlation structure of the exposome during pregnancy to better understand the relat

29 unexplained disease risks are caused by the exposome (E; representing all exposures) and G x E inter

30 ence is attributable to environmental (human exposome) factors through the gene-environment interacti

31 The exposome has been defined as the totality of exposures i

32 Considerable interest in defining the toxic exposome has been spurred on by the realization that mos

33 Three domains of the exposome have been identified: internal, specific extern

34 nship between key components of the external exposome in the prenatal and early-life periods and thei

35 Eliciting information on the exposome is daunting and not feasible at present; the un

36 The exposome is defined as the totality of all human environ

37 The "exposome" is a term describing the summation of one's li

38 The "exposome" is defined as "the totality of human environme

39 The 'toxic exposome' is the complete collection of chronically or a

40 of their time indoors, the built environment exposome merits particular attention.

41 tabolites that were detected in the effluent exposome of fish, 6 were nonsteroidal anti-inflammatory

42 the understanding of the thyroid disrupting exposome of polar bears.

43 ion efforts are being guided by study of the exposome (or collective environmental exposures beginnin

44 An exposome perspective on environmental enteric dysfunctio

45 mportant concept developments concerning the exposome, predictive health, and complex pathobiology se

46 The exposome provides an excellent scientific framework for

47 Exposome-related efforts aim to document the totality of

48 We found that the saliva exposome represents at least 14 metabolic pathways, incl

49 ations of total environmental exposures, the exposome, require coordinated interdisciplinary efforts.

50 We describe the biomonitoring needs of exposome research and approaches and recommendations tha

51 Here we review the historical origins of exposome research and define a new concept, the metaexpo

52 Understanding Lifetime Exposures (HERCULES) Exposome Research Center at Emory University held the fi

53 the concept of the exposome, the Health and Exposome Research Center: Understanding Lifetime Exposur

54 exposures to specific biological responses, exposome research could serve to improve understanding o

55 al exposures through biomonitoring is key to exposome research efforts.

56 is currently discussed under the heading of exposome research.

57 needs of epidemiologists, toxicologists and exposome scientists, the latest release of T3DB has been

58 ment by introducing the concept of Lifestage Exposome Snapshots (LEnS).

59 ls of thought, that is, concepts such as the exposome, social determinants of health (SDoH), and citi

60 he LEnS framework encourages organization of exposome studies based on windows of susceptibility for

61 otential of such data to inform clinical and exposome studies conducted early in life.

62 Future exposome studies should interpret exposure effects in li

63 permit adjustment for confounding in future exposome studies.

64 While our exposome summation models do not fully capture the compl

65 ter at Emory University held the first Emory Exposome Summer Course from 13-17 June 2016.

66 EnS concept is a practical refinement to the exposome that accounts for total exposures during partic

67 To promote and develop the concept of the exposome, the Health and Exposome Research Center: Under

68 Our objective was to apply the exposome to children's health risk assessment by introdu

69 framework for intentionally controlling the exposome to protect public health.

70 new "discovery" path for decoding the human exposome using biomarkers in breath and other biological

71 The term "exposome" was coined in 2005 to underscore the importanc

72 The term "exposome" was originally coined in 2005 and defined as t

73 s role in understanding human health and the exposome, we aimed to centralize and integrate exposure

74 ristopher Wild introduced the concept of the exposome, which encompasses environmental exposures and

75 ures motivates characterization of the blood exposome, which includes all biologically active chemica

76 The exposome, which is dynamic and variable, consists of all

77 asses of chemicals in archived biospecimens, exposome-wide association studies (EWAS) are being condu

78 gitudinal epigenome-wide, envirome-wide, and exposome-wide association studies (LEWAS) of the genome,