ライフサイエンスコーパス: exposure

1 en loss and immune activation after pathogen exposure).

2 ur method to detect e-cig aerosol third-hand exposure.

3 ing E2f3a overexpression or repeated cocaine exposure.

4 tabolism in adipose depots during acute cold exposure.

5 ns and often seems to depend on the route of exposure.

6 onomic differences in the response to nature exposure.

7 rovide sufficient protection for extended UV exposure.

8 including extreme physical exertion and heat exposure.

9 ple miRNAs, including miR126, following eCig exposure.

10 isrupted actin filament networks after 2,4-D exposure.

11 ls (BEAS-2B) through an air-liquid interface exposure.

12 th cohort with relatively low levels of lead exposure.

13 increment in annual residential black carbon exposure.

14 om inactivation when present during the H2O2 exposure.

15 imum (1.25 [1.06-1.47] per kJ/m(2)) UVR dose exposure.

16 human bronchial epithelial cells after 4-day exposure.

17 rofiles of nasal cells, before and after HDM exposure.

18 facilitated by developmental stress hormone exposure.

19 rs for a target gene independent of stimulus exposure.

20 allergic patients and beekeepers after venom exposure.

21 k for maintaining PTSD symptoms after trauma exposure.

22 are altered in those with prolonged cannabis exposure.

23 ating both AHR and mucus secretion after HDM exposure.

24 exposed body sites 22 to 24 hours after sun exposure.

25 ded as a method that causes a high radiation exposure.

26 utoproteolysis and hence, in Stachel peptide exposure.

27 AFB1 exposure, possibly combined with other exposures.

28 onfirmed, probable, suspected, or non-rabies exposures.

29 ry was slow relative to the interval between exposures.

30 Despite antibiotic exposure, 15 of the 39 patients (approximately 38%) colo

31 ity: +109%; time moving: +44%) shortly after exposure (30 min), and impaired motor functions (falls:

32 Greater benzodiazepine exposure (75-25th percentile) was significantly associat

33 Acute corticosterone exposure accelerated metamorphosis increased survival in

34 -2012, to determine variability in radiation exposure according to facility for this indication, and

35 s constructed that would provide piperaquine exposures across all ages comparable to the exposure cur

36 imandibles exhibited lower rates of membrane exposure and a noteworthy, ectopic bone formation above

37 al exposure, confounding from causes of both exposure and disease, identifying periods of heightened

38 e association between prenatal maternal lead exposure and epigenome-wide DNA methylation in umbilical

39 des a critical host defense against pathogen exposure and epithelial injury, yet little is known abou

40 cytokine responses induced by nasal allergen exposure and humoral immune responses that included IgE-

41 inverse association was found between ozone exposure and PEF.

42 other mammals contain PFOS from both direct exposure and precursor degradation.

43 difiable risk factors such as benzodiazepine exposure and short-term outcomes.

44 testosterone as a sensitive biomarker of POP exposure and that seasonal patterns are investigated whe

45 de that, at concentrations relevant to human exposure and within a particular narrow 'early window' o

46 f children to test associations between iron exposures and mood, emotion, cognition, and memory; anim

47 lishment of human epigenetic markers of iron exposures and oxidative stress that could be monitored f

48 cial class, home overcrowding, and pollution exposure) and FEV1 and FVC trajectories between ages 43

49 d how the timing of exercise relative to AOM exposure, and amount of exercise, affected tumor number

50 ilm matrix components within 1 minute of AMF exposure, and combination studies of antibiotics and AMF

51 s across its subtypes, some unrelated to sun exposure, and extends potential involvement of the non-c

52 4 reactivity and CD4-induced non-nAb epitope exposure, and increase thermal stability while maintaini

53 iods of heightened vulnerability to chemical exposures, and determining the effects of chemical mixtu

54 uline grid resolution) to estimate annual O3 exposures, and estimated total respiratory deaths in 201

55 People with higher OC exposure are likely inhaling more fresh OC2 and OC3, sin

56 is incompletely understood, but enteral feed exposures are believed to affect risk.

57 We treated exposure as time-varying when it was updated annually an

58 After prolonged P. aeruginosa exposure, ASER-specific SOD-1 expression is diminished.

59 hat were attributable to long-term annual O3 exposure based on the updated relative risk estimates an

60 (extreme 75th percentile for cumulative risk exposure between ages 6 and 24 years) of systolic BP, to

61 e and Exacerbation Risk), was used to assess exposure, breathing problems, tiring easily, and acute r

62 racial/ethnic and regional differences, high exposure burden to multiple allergens was most consisten

63 ar length and weight as newborns without HIV exposure, but their head circumference was smaller (34.0

64 This model was extended to charged particle exposures by integrating Monte Carlo calculated dose dis

65 Antibiotic exposure can alter the gut microbiome.

66 Personal heat exposure can be measured directly with wearable monitors

67 Moreover, both neonatal and adult THS exposure caused a significant increase in percentage of

68 Finally, high sediment exposure caused an immediate reduction in respiration ra

69 Environmental exposure chambers are currently already used in phase 2,

70 distinct models-in utero valproic acid (VPA) exposure, CNTNAP2 knockout and FMR1 knockout-layer 5 sub

71 in patients on hemodialysis resulted in drug exposure comparable with that of the standard dose (5 mg

72 Adolescent intermittent ethanol (AIE) exposure compromises neural function into adulthood.

73 enges include accurately estimating chemical exposure, confounding from causes of both exposure and d

74 exposures across all ages comparable to the exposure currently seen in a typical adult with standard

75 ning strategies (n=76; 33.9 cases per 10 000 exposure days; relative risk [RR] 0.70, 95% CI 0.50-0.98

76 rction varied in sensitivity analyses and by exposure definition (HR range, 1.13 [CI, 0.78 to 1.64] t

77 ever, after 28 years, the separate and joint exposures did not predict MSDs.

78 with EVD, 47.6% (229 of 481) had high level exposure (direct contact with a corpse, body fluids, or

79 patch whose original color changes upon sun exposure due to its UV-responsive capabilities that are

80 Importantly, IFN-gamma exposure during activation reduced the cytotoxicity of h

81 at provides an interval of no or low nitrate exposure during each 24-h period.

82 ficantly and inversely associated with PM2.5 exposure during midgestation (weeks 12-25 for cord blood

83 condition recently linked to gadolinium (Gd) exposure during MRI with contrast.

84 nsitivity analysis restricted to artemisinin exposures during the embryo sensitive period (6-12 wk ge

85 The abundance and diversity of microbial exposures during the first months and years of life have

86 er, no association was found for antibiotics exposure early in life and objective atopy measurements

87 of contextual fear conditioning, context pre-exposure facilitation, allows us to directly test the re

88 performed at 3 h of the in vitro antifungal exposure failed to detect C. glabrata isolates with echi

89 een 1980 and 2010, population-weighted PM2.5 exposures fell by about half, and the estimated number o

90 w) and a control group, with a 6 day aqueous exposure, followed by a 7 day depuration phase under flo

91 is of OC2 and OC3 as markers of fresh source exposure for Pittsburgh, the relationship seemed to hold

92 0.92, 1.05), skin reaction to prolonged sun exposure (for painful burn with blisters vs. practically

93 tion, and the association was persistent for exposure from >/=6 procedures in all sensitivity analyse

94 per procedure; 95% CI, 1.05-1.16 and OR when exposure from >/=6 procedures, 3.08; 95% CI, 1.77-5.37),

95 per procedure; 95% CI, 1.03-1.14 and OR when exposure from >/=6 procedures: 2.58; 95% CI, 1.43-4.69).

96 Experiments involved two exposure groups (high and low) and a control group, with

97 Subjects were divided into time varying exposure groups according to antithrombotic treatment.

98 tegorize participants into high and low drug exposure groups.

99 tile-range increment for pollutants and high exposure (>/=75th percentile) for air toxics after adjus

100 High arsenic exposure has been related to diabetes, but at low-modera

101 effects of particulate ambient air pollution exposure have focused on high-income countries, which ha

102 Long-term increased lithium exposure in drinking water may be associated with a lowe

103 nate cord serum associated with prenatal iAs exposure in participants from the Biomarkers of Exposure

104 set at the minimum or fifth percentile of O3 exposure in the most recent CPS-II analysis.

105 ct on gene expression compared to 3R4F smoke exposure in vitro.

106 These results suggest that repeated cocaine exposure in vivo disrupts the balance between excitation

107 d the fetal and postnatal n-6/n-3 PUFA ratio exposure in wild-type offspring under standard maternal

108 More research about exposures in schools, childcare facilities, and homes is

109 These findings suggest that diverse biologic exposures, including allergens and endotoxin, in urban h

110 BPA exposure increased Nrf2 binding to a putative antioxidan

111 experiments to determine whether antibiotic exposure increases susceptibility to infection by opport

112 eviously hypothesized to stem from aflatoxin exposure, indeed likely represents AFB1 exposure, possib

113 ults, in combination with the high levels of exposure, indicate a potentially serious human health bu

114 and metabolomic profiles suggested that MPs exposure induced disturbance of energy and lipid metabol

115 Aberrant PAD exposure induces a signaling cascade that leads to disru

116 Ancestral TBT exposure induces global changes in DNA methylation and a

117 ted how the relationships between early-life exposures (infant lower respiratory infection, manual so

118 We used exposure information on the baseline questionnaire to id

119 h regions according to the route of allergen exposure (inhaled vs food allergens).

120 iming of confounder measurements relative to exposure initiation and the rate of change in the confou

121 pathways that influence recovery from noise exposure is an important step forward in understanding N

122 Prenatal inorganic arsenic (iAs) exposure is associated with health effects evident at bi

123 of adverse health effects through inhalation exposure is critical to mitigating its potential impact

124 response, specifically whether systemic drug exposure is crucial for in vivo efficacy.

125 t, adult bacterial diversity during parasite exposure is not correlated with parasite establishment i

126 esting mTORC1 inhibition during asparaginase exposure is not driven via eIF2-ATF4-Sestrin2.

127 rs but BPA pharmacokinetics following dermal exposure is not understood.

128 jor mechanism of skin injury common to these exposures is radiation-induced oxidative stress.

129 Our findings indicate prenatal WD exposure leads to age-specific changes in voluntary phys

130 ional mouse model of AUD showed that alcohol exposure leads to PCSK9 downregulation.

131 Similar to in many women with PCOS, DHT exposure led to reduced adiponectin levels, larger adipo

132 The 0.05-mg/m3 and 0.35-mg/m3 exposure levels yielded similar associations.

133 This is a hospital-based, exposure-matched and retrospective longitudinal study.

134 to show that some children's PCB inhalation exposure may be equal to or higher than their exposure t

135 Effect estimates based on a single day of exposure may underestimate true effects for respiratory

136 a such as environmental waters or toxicology exposure media, the same redox transformations can occur

137 ephosphorylation of Akt after 2 h of hypoxic exposure might deactivate RNA-binding protein BRF1, henc

138 That sex-biased exposure might translate to sex-specific adverse outcome

139 passive samplers to assess cumulative 5-day exposure of 30 individuals to polar PRs.

140 Exposure of Africans to fatal pathogens, such as Plasmod

141 Increased exposure of beta-(1,3)-glucan to the immune system occur

142 ity, and was directly cytotoxic, whereas the exposure of cells to equivalent doses of the OSPW-OF had

143 enhancement of antiproliferative effect upon exposure of cells to irradiation by visible light, proba

144 Exposure of cultured fibroblasts to uniaxial cyclic stre

145 Exposure of cultured neurons to fetal plasma or to secre

146 Short exposure of HCV-infected cells to daclatasvir reduced vi

147 In vitro exposure of human whole blood to PhNHOH and NOB demonstr

148 Exposure of hydrated cysts to host plant root exudates r

149 lop improved native-like trimers that reduce exposure of non-nAb epitopes in the V3-loop and trimer b

150 Exposure of P1 ECs to MPs shed from senescent P3 cells o

151 Our results revealed that after the exposure of synthesized aerosol to the insect antenna, A

152 t mitochondria and then dissociate following exposure of the BAK BH3 and BH4 domains before BAK homod

153 ssection of the rectum resulting in a better exposure of the distal rectum and presumed better outcom

154 The systemic exposure of the free drug was much lower than that achie

155 It is modelled by exposure of the protein to non-physiological low pH in v

156 Exposure of these cells to allergens induces the release

157 on on the baseline questionnaire to identify exposures of interest.

158 out the detrimental effects of tobacco smoke exposure on children's respiratory health.

159 ndering the attribution of direct effects of exposure on severe health outcomes.

160 Prenatal ethanol exposure (PE) leads to increased addiction risk which co

161 The increase of temperature and heat exposure period decreased the protein bioaccessibility.

162 oxin exposure, indeed likely represents AFB1 exposure, possibly combined with other exposures.

163 8 h at 20 degrees C prior to low-temperature exposure (pre-conditioning, PC).

164 Following oxygen exposure, preterm infants frequently develop chronic lun

165 The efficacy of HIV pre-exposure prophylaxis (PrEP) relies on adherence and may

166 from Europe, suggest that early-life farming exposures protect against childhood asthma and allergy;

167 Here, we reveal that sucrose cue exposure recruited a more excitable ensemble in the nucl

168 Moreover, activation following trauma exposure reduced the susceptibility for PTSD-like sympto

169 rolein (28 mug m(-3)) exceeded the acute 1-h exposure REL for the highest emitting vaporizer/voltage

170 The estimated exposure-response relationship for Vibrio infections at

171 There was no evidence of a threshold in the exposure-response relationship.

172 NO exposure resulted in immediate and reversible intracellu

173 debris are more common, primary ocular blast exposure resulting from blast wave pressure has been rep

174 Moreover, the transcriptome under high light exposure revealed candidate genes that could be involved

175 This study explores two exposure routes of OHCs, ingestion of OHCs (i) via house

176 are constrained by the types of materials or exposure scenarios that can be configured into such colu

177 Inhibition of signaling after ligand exposure selectively delayed proliferation in cells with

178 ine-N-oxide), thus in effect linking diverse exposures such as those from dietary intake and the micr

179 itude scaled with the duration of pre-change exposure, suggesting a time-dependent decision threshold

180 were recruited preferentially during context exposure, suggesting their role in encoding context repr

181 ory B cell antibodies elicited by natural Pf exposure that potently inhibited parasite transmission a

182 ery caused carry-over toxicity in subsequent exposures, thereby resulting in a sequence effect-but on

183 xposure may be equal to or higher than their exposure through diet.

184 airway inflammation is triggered by allergen exposure through several steps including release of IL-3

185 Exposure to 13 physicochemically distinct ENMs caused a

186 Exposure to 5 localized civil conflict fatalities (mean

187 Childhood exposure to a farm environment has been shown to protect

188 Repeated exposure to a novel physical environment eventually lead

189 lar switch that dictates cell fate following exposure to adverse environments.

190 (aOR = 2.4; 95% CI = 1.0-5.8; P = .047), and exposure to all 3 at-risk housing types (adobe, mud, and

191 Exposure to ambient air pollution increases morbidity an

192 Exposure to an AMC detailing policy was associated with

193 ab, stratified by disease category, previous exposure to anti-GD2 antibody therapy, and tumour MYCN a

194 ation of ART in people who have had previous exposure to antiretroviral drugs.

195 Exposure to any mold or dampness indicator was associate

196 osure in participants from the Biomarkers of Exposure to ARsenic (BEAR) pregnancy cohort, in Gomez Pa

197 Exposure to BAR501 shifted intestinal macrophages from a

198 In human CD4(+) T cells, a 5-d exposure to BET inhibitors was accompanied by a signific

199 Exposure to blood-stage malaria infection is often persi

200 Exposure to bullying is associated with poor mental heal

201 ) EVs ratio and may be mediated by prolonged exposure to cellfree HbF.

202 k for identification of biomarkers of public exposure to chemicals via combined human metabolism and

203 resistance arising in most tumors following exposure to chemotherapy.

204 Exposure to cocaine and the test chamber induced rapid a

205 -essential genes essential for growth during exposure to colistin (n = 35), imipenem (n = 1) or cipro

206 minced into 1 mm(3) pieces to minimize time exposure to collagenase digestion and preserve cell viab

207 se ecological and human-health risks through exposure to contaminated soil and groundwater.

208 Exposure to dog and cat allergens in DCC often reached l

209 We found that exposure to drug-related cues reinstated cocaine-seeking

210 ion and selection of new biomarkers of human exposure to drugs with scarce or unknown human metabolis

211 Exposure to durvalumab increased cediranib area under th

212 valent or higher nicotine delivery, an acute exposure to e-cigarette aerosol had a reduced impact on

213 ng and transgenerational effects of maternal exposure to early-life stress on several phenotypic trai

214 sciences; however, the toxicology of chronic exposure to environmentally relevant concentrations of t

215 thmically induced in young flies by constant exposure to exogenous oxidative stress, and this upregul

216 otic infection with FeLV.IMPORTANCE Domestic exposure to gammaretroviruses such as feline leukemia vi

217 se model, we examined the effect of neonatal exposure to genistein on gene specific mRNA levels in va

218 DNA adducts reflect the internal exposure to genotoxicants and can serve as biomarkers fo

219 Our findings also suggest that prior exposure to H1 or type B influenza may differentially af

220 ently are infected with HBV or have had past exposure to HBV.

221 ng variations in CHO cell culture media upon exposure to high temperature short time (HTST) treatment

222 This study examined the impact of brief exposure to hyperoxia using diffusion tensor imaging (DT

223 lar fat pad express the IL-1 receptor and on exposure to IL-1alpha polarize to a highly inflammatory

224 Initial EMT was induced by prolonged exposure to IL6, a cytokine also generated by the tumor-

225 y settings, populations experience recurrent exposure to inflammatory agents that catalyze fluctuatio

226 how a disrupted re-entry into dormancy after exposure to inflammatory stress stimuli.

227 m veneficum and Gyrodinium instriatum) after exposure to IRI-160AA.

228 osure to NO2(-) under normoxic conditions or exposure to ischemia alone results in minimal S-nitrosat

229 enotypic changes we observed after prolonged exposure to lumican.

230 e used a compartmental model to estimate (1) exposure to maternal GBS colonization, (2) cases of infa

231 In the yeast Saccharomyces cerevisiae, the exposure to mating pheromone activates a prototypic mito

232 Prenatal exposure to mercury, a known neurotoxic metal, is associ

233 rs of age (OR 1.31; 95% CI 1.08-1.59), while exposure to mold odor (OR 1.29; 95% CI 1.03-1.62) and vi

234 tter in soils of arid regions), reduce human exposure to mycotoxins in buildings and our food-supply

235 more accurate risk assessment of children's exposure to mycotoxins mixtures in food.

236 x isotope-coded affinity tag), we found that exposure to NO2(-) under normoxic conditions or exposure

237 /nitrative stress are a function of prenatal exposure to NP/BPA and inflammation in 241 mother-fetus

238 the beta2 adrenergic receptor (beta2AR) upon exposure to orthosteric ligands with different efficacie

239 noxygenic photosynthetic organisms, in which exposure to oxygen is low, chlorophyll-to-carotenoid tri

240 lysis revealed positive associations between exposure to p,p'-DDE and BMI z-score (beta=0.13 BMI z-sc

241 AhR was the most sensitive one activated by exposure to PAHs.

242 rapidly elaborate effector functions upon re-exposure to pathogens, but also have many properties in

243 ty in medial prefrontal cortex (MPFC) during exposure to persuasive messages can predict health behav

244 Monitoring human exposure to pesticides and pesticide residues (PRs) rema

245 In this cohort, prenatal exposure to PFASs was associated with small increases in

246 ng the possibility to assess population-wide exposure to PFRs.

247 rgy-promoting effects in children because of exposure to plasticizers, such as phthalates, findings o

248 Our findings illustrate that mountain lion exposure to PLVA is relatively common but does not routi

249 Exposure to PM and NO2 air pollution was associated with

250 ntify the adjusted odds ratios (aORs) of the exposure to PM10 and the risks of fetal cardiovascular m

251 Exposure to pollutants, such as ozone, exacerbates airwa

252 s study, we examined the association between exposure to positive or negative fluid balance, compared

253 The results suggest that exposure to prions in the environment is greater where p

254 lly form in 5'-GG-3' sequence contexts after exposure to reactive oxygen species.

255 nterest in negative outcomes associated with exposure to repetitive brain trauma (RBT) continues to s

256 ovide novel evidence of associations between exposure to some pesticides and RA in male farmers.

257 on that prepares the organism for successive exposure to stressful stimuli.

258 Exposure to systemic antibiotics destabilized the wound

259 thors present compelling evidence that early exposure to tanning beds advances the date of diagnosis

260 Exposure to TDF, but not other ARVs, was an independent

261 ol and forms an ethanol-based gel-phase upon exposure to the aqueous tumor environment.

262 Re-exposure to the context in which the threat was experien

263 We investigate how exposure to the environment affects the electrical prope

264 In parallel, direct exposure to the HIV-related proteins Tat or gp120 induce

265 ew the literature on the association between exposure to the pesticide DDT and its metabolites and ob

266 al features of 3 patients and investigate IV exposure to the tablet's inert ingredients as a possible

267 , the association between poultry intake and exposure to these arsenic species, as reflected in eleva

268 d in Japanese medaka (Oryzias latipes) after exposure to two concentrations of 17beta-estradiol (E2be

269 e methodologies and suitable for identifying exposure to unknown organophosphorus agents.

270 d may be rooted partially in early childhood exposure to unpredictable events and environments.

271 Unexpectedly, its exposure to UV light affords, after reductive eliminatio

272 We show that short-term exposure to various forms of PE, displaying different mo

273 ity and selectivity by precisely controlling exposure to vesicles with lipid compositions that mimic

274 Exposure to violence continues to be a growing epidemic,

275 We assessed exposure to violence through either the urban district-l

276 gister were included, with information about exposure to warfarin in the national quality register Au

277 f North Carolinians facing elevated risks of exposure to waterborne contaminants because of their rel

278 estimate the association between short-term exposures to ambient fine particulate matter (PM2.5) and

279 insights into the contribution of mutagenic exposures to cancer incidence.

280 Many participants reported multiple exposures to cold.

281 on is associated with significantly elevated exposures to combustion emissions.

282 unclear, and the possible effect of multiple exposures to fly bites on transmissibility has not been

283 ciency virus (HIV) emergence following human exposures to simian immunodeficiency virus (SIV), an und

284 -PCR assay indicated that compound 1 and DBL exposure up-regulated the expression of gene mcyB and do

285 Although exposure variability showed significant racial/ethnic an

286 nt is attributable to surgery and anesthesia exposure versus patients' baseline factors and hospital

287 At the population level, first-trimester exposure was associated with all outcomes compared with

288 ernal traits, first-trimester antidepressant exposure was associated with preterm birth (OR, 1.34 [95

289 Information on AED exposure was available in the subset of offspring from J

290 Exposure was defined as a total TXA dose greater than 10

291 Finally, although serum exposure was not necessary for drusen formation, COL4 ac

292 Lithium exposure was statistically significantly different betwe

293 Drosophila heart model for long-term hypoxia exposure, we found that hypoxia caused heart dysfunction

294 notypes that predict higher plasma efavirenz exposure were associated with increased risk of suicidal

295 Antimalarial exposures were ascertained by self-report or active dete

296 nes both at baseline and following endotoxin exposure when compared with infants with transient egg a

297 sponse following silver nanoparticle (Ag NP) exposure, which was dependent upon key physicochemical p

298 sed CCR5 expression after high-dose allergen exposure while CXCR4, CXCR5, CCR6, and CCR7 expression r

299 exploring the influence of early and midlife exposures will further advance our understanding of the

300 els to examine associations of prenatal lead exposure with DNA methylation in cord blood at epigenome

301 ce for positive association of tobacco smoke exposure with rhinitis, while the effect is mainly confi