ライフサイエンスコーパス: expression quantitative trait loci

1 sociation studies and exhibit enrichment for expression quantitative trait loci.

2 We highlight 16 genes based on expression quantitative trait loci.

3 controlling the expression traits are called expression quantitative trait loci.

4 ndscape of genetic interactions between gene expression quantitative trait loci.

5 at some top heritable features coincide with expression quantitative trait loci.

6 Analyses of expression profiles and expression quantitative trait loci across different tiss

7 Expression quantitative trait loci analyses of top assoc

8 Gene expression quantitative trait loci analyses showed a sig

9 Expression quantitative trait loci analysis confirmed pr

10 Expression quantitative trait loci analysis of postmorte

11 Expression quantitative trait loci analysis revealed tha

12 The expression quantitative trait loci analysis revealed tha

13 ntially linked to breast cancer risk loci in expression quantitative trait loci analysis, supporting

14 In the second phase of expression quantitative trait loci analysis, we attempt

15 Our expression quantitative trait loci analysis, which was b

16 applied it to 32,373 variants from 3,642 cis-expression quantitative trait loci and control regions.

17 We mapped cis-acting expression quantitative trait loci and found 24 non-HLA

18 everal of which are supported by independent expression quantitative trait loci and gene expression a

19 nucleotide polymorphisms identified through expression quantitative trait loci and genome-wide assoc

20 ngle-nucleotide polymorphisms that are known expression quantitative trait loci and have been associa

21 d investigated possible associations between expression quantitative trait loci and NOTCH4 expression

22 s based on functional annotation, cis-acting expression quantitative trait loci and pathway analyses-

23 ecific modifications can be colocalized with expression quantitative trait loci and single nucleotide

24 ding, provide a molecular mechanism for some expression quantitative trait loci, and are risk factors

25 tion at linked enhancers, by the presence of expression quantitative trait loci, and by allele-specif

26 ore detail by performing genetic risk score, expression quantitative trait loci, and variant*ever-smo

27 On a biological level, eQTL (expression quantitative trait loci) are genetically comp

28 These loci were co-localized with expression quantitative trait loci associated with gene

29 Two of the 7 replicated SNPs were cis-acting expression quantitative trait loci associated with gene

30 We identify 57 expression quantitative trait loci at 35 risk loci, whic

31 In recent years, multiple eQTL (expression quantitative trait loci) catalogs have become

32 (p = 1.4 x 10(-9)), which demonstrated a cis-expression quantitative trait loci (cis-eQTL) effect on

33 at each day and found evidence of cis-acting expression quantitative trait loci (cis-eQTL) for 869 ex

34 Of the 47 SNPs, 39 were cis-expression quantitative trait loci (cis-eQTL) for TNFSF8

35 Mapping cis-acting expression quantitative trait loci (cis-eQTL) has become

36 cross 112 islet samples to produce dense cis-expression quantitative trait loci (cis-eQTL) maps.

37 We then tested the 16 putative cis-expression quantitative trait loci (cis-eQTL) SNPs for a

38 "natural knockouts." We identified 1222 cis-expression quantitative trait loci (cis-eQTL) that contr

39 integrate both gene expression data and cis-expression quantitative trait loci (cis-eQTL), for model

40 ci were also associated with one or more cis-expression quantitative trait loci (cis-eQTLs) and/or sp

41 cis-regulating mutations, the number of cis expression quantitative trait loci (cis-eQTLs) discovere

42 dom forests trained to recognize SNVs in cis-expression quantitative trait loci (cis-eQTLs) using a s

43 iation affecting gene expression levels (cis expression quantitative trait loci [cis-eQTLs]) and prot

44 We validate our findings in expression quantitative trait loci cohorts, which togeth

45 We find that 8q24 risk alleles are expression quantitative trait loci correlated with reduc

46 r annotating associated regions using GRAIL, expression quantitative trait loci data and correlations

47 The results were integrated with valve expression quantitative trait loci data obtained from 22

48 elation analyses among other BBS genes in an expression quantitative trait loci data set demonstrate

49 us relating epidemiological observations and expression quantitative trait loci data to a systems mod

50 Integrating our results with expression quantitative trait loci data, we provide evid

51 ased on high-throughput sequencing (HTS) and expression quantitative trait loci data.

52 sed in the cerebellar cortex of patients and expression quantitative trait loci database mining showe

53 Increasing number of eQTL (Expression Quantitative Trait Loci) datasets facilitate

54 These selected transcripts are candidate expression Quantitative Trait Loci, differentially regul

55 arks of transcriptional activation-including expression quantitative trait loci, disease-associated p

56 Distal expression quantitative trait loci (distal eQTLs) are ge

57 xpression (GTEx) data set, we implemented an expression quantitative trait loci epistasis analysis to

58 on genome-wide association studies results, expression quantitative trait loci (eQTL) analyses, and

59 netic data and genome-encoded features), and expression quantitative trait loci (eQTL) analyses, in a

60 of high linkage disequilibrium identified by expression quantitative trait loci (eQTL) analyses.

61 Functionality of these SNPs was assessed by expression quantitative trait loci (eQTL) analysis and a

62 controls, and validated these results using expression quantitative trait loci (eQTL) analysis and c

63 Expression quantitative trait loci (eQTL) analysis is a

64 Expression quantitative trait loci (eQTL) analysis links

65 We conducted an expression quantitative trait loci (eQTL) analysis using

66 Using expression quantitative trait loci (eQTL) analysis, we f

67 uted genotype data, we identified 47,587 cis-expression quantitative trait loci (eQTL) and 6,695 tran

68 nts with NSCLC from Taiwan and assessment of expression quantitative trait loci (eQTL) and differenti

69 of functional non-coding variants, including expression quantitative trait loci (eQTL) and disease-as

70 Fourth, expression quantitative trait loci (eQTL) and gene-expre

71 altered transcription factor binding to both expression quantitative trait loci (eQTL) and genome-wid

72 erlying sex determination, we took the first expression quantitative trait loci (eQTL) approach in a

73 ci and human gene expression levels using an expression quantitative trait loci (eQTL) approach.

74 otein-coding genes, but have significant cis-expression quantitative trait loci (eQTL) associations w

75 Genevar allows researchers to investigate expression quantitative trait loci (eQTL) associations w

76 ified 11,204 cis and 3,791 trans independent expression quantitative trait loci (eQTL) by using linea

77 onships among genotypes and phenotypes using expression quantitative trait loci (eQTL) data from gene

78 Notably, expression quantitative trait loci (eQTL) data revealed

79 Regulatory feature analysis and expression quantitative trait loci (eQTL) data showed th

80 We utilized genomic variants and expression quantitative trait loci (eQTL) data to analyz

81 protein protein interaction (PPI) as well as expression quantitative trait loci (eQTL) data to identi

82 of AH and applied it to three GWASs and four expression quantitative trait loci (eQTL) datasets.

83 ning genotype and sequence data, such as for expression quantitative trait loci (eQTL) detection, req

84 The standard expression quantitative trait loci (eQTL) detects polymo

85 Genome-wide mapping identified 25 660 expression quantitative trait loci (eQTL) for 17 311 gen

86 Local expression quantitative trait loci (eQTL) generally act

87 The studies of expression quantitative trait loci (eQTL) have shown tha

88 We examined all four expression quantitative trait loci (eQTL) hot spots with

89 er of these genes were controlled by several expression quantitative trait loci (eQTL) hotspots that

90 Studies of gene expression quantitative trait loci (eQTL) in different o

91 ing that lipid-associated loci that are also expression quantitative trait loci (eQTL) in human liver

92 In contrast to results from mapping of expression quantitative trait loci (eQTL) in linkage stu

93 Here we map expression quantitative trait loci (eQTL) in peripheral

94 ipt and protein expression levels and mapped expression quantitative trait loci (eQTL) in primary den

95 Studies of expression quantitative trait loci (eQTL) indicate that

96 Expression quantitative trait loci (eQTL) mapping concer

97 secting the genetic basis of complex traits, expression quantitative trait loci (eQTL) mapping has at

98 Genome-wide gene expression quantitative trait loci (eQTL) mapping have b

99 Expression quantitative trait loci (eQTL) mapping is a p

100 Expression quantitative trait loci (eQTL) mapping is a w

101 ymetrix GeneChip probe set summaries and the expression quantitative trait loci (eQTL) mapping result

102 Expression quantitative trait loci (eQTL) mapping studie

103 d the Sen-Churchill framework to accommodate expression quantitative trait loci (eQTL) mapping studie

104 Expression quantitative trait loci (eQTL) mapping studie

105 dies such as genetical genomics [also called expression quantitative trait loci (eQTL) mapping] in wh

106 Thus, the expression quantitative trait loci (eQTL) of the gene, w

107 We identified a depletion of expression quantitative trait loci (eQTL) on the X Chrom

108 user-supplied functional annotation such as expression quantitative trait loci (eQTL) or Hi-C genome

109 ide association studies (GWAS) identify 5311 expression quantitative trait loci (eQTL) regulating the

110 We identified genome-wide expression quantitative trait loci (eQTL) regulating var

111 Analysis of expression quantitative trait loci (eQTL) significantly

112 Expression quantitative trait loci (eQTL) studies are an

113 Expression quantitative trait loci (eQTL) studies have d

114 Genome-wide expression quantitative trait loci (eQTL) studies have e

115 Recent expression quantitative trait loci (eQTL) studies have e

116 Expression quantitative trait loci (eQTL) studies have e

117 Genome-wide expression quantitative trait loci (eQTL) studies have e

118 Genome-wide expression Quantitative Trait Loci (eQTL) studies in hum

119 Expression quantitative trait loci (eQTL) studies invest

120 ntegrative genomics, exemplified by numerous expression Quantitative Trait Loci (eQTL) studies.

121 the error rate for reported findings in many expression quantitative trait loci (eQTL) studies.

122 ecting the genetic basis of common diseases, expression quantitative trait loci (eQTL) study has attr

123 of GWAS, as well as in a multi-tissue mouse expression quantitative trait loci (eQTL) study where ou

124 We identified approximately 4000 expression quantitative trait loci (eQTL) that allowed u

125 relative expression levels, gene network and expression quantitative trait loci (eQTL) that regulate

126 e, it is important to map the aforementioned expression quantitative trait loci (eQTL) using a statis

127 ciated variants are over-represented amongst expression quantitative trait loci (eQTL) variants.

128 Phenotypic and expression quantitative trait loci (eQTL) were mapped.

129 ll other designs considered for detection of expression quantitative trait loci (eQTL) with additive

130 ative traits, we identified several thousand expression quantitative trait loci (eQTL) with LOD score

131 ch condition and identified several thousand expression quantitative trait loci (eQTL), gene-by-envir

132 In genomewide mapping of expression quantitative trait loci (eQTL), it is widely

133 In comparison with expression quantitative trait loci (eQTL), mQTL detected

134 Except rs3130320 as a known expression quantitative trait loci (eQTL), rs3806932 and

135 pulations have facilitated identification of expression quantitative trait loci (eQTL), the genetic d

136 Identification of expression Quantitative Trait Loci (eQTL), the genetic l

137 Mapping expression quantitative trait loci (eQTL), we identify 4

138 affect levels of gene expression are called expression quantitative trait loci (eQTL), which can pro

139 further demonstrate that lncRNAs overlapping expression quantitative trait loci (eQTL)-associated sin

140 on in gene transcription between patients as expression quantitative trait loci (eQTL).

141 94 genes and a highly overlapping set of cis-expression quantitative trait loci (eQTL).

142 is influenced by variants commonly known as expression quantitative trait loci (eQTL).

143 can be exploited while mapping multi-tissue expression quantitative trait loci (eQTL).

144 effects of such variants can be detected as expression quantitative trait loci (eQTL).

145 e traits relevant to human health, including expression quantitative trait loci (eQTL).

146 ically in structured populations to identify expression quantitative trait loci (eQTL).

147 become a powerful paradigm for mapping gene expression quantitative trait loci (eQTL).

148 e gene as a quantitative trait and map it to expression quantitative trait loci (eQTL).

149 expression levels of transcripts are called expression quantitative trait loci (eQTL).

150 SNPs, and when overlapping them with adipose expression quantitative-trait loci (eQTL) from the same

151 n-synonymous SNPs (in NDUFA11 and KIAA1755), expression quantitative trait loci (eQTLs) (influencing

152 methylation QTLs (P<0.001) and frontal lobe expression quantitative trait loci (eQTLs) (P=0.001) was

153 Expression quantitative trait loci (eQTLs) across all an

154 gen receptor (ER)-positive breast cancer are expression quantitative trait loci (eQTLs) acting upon m

155 We identified 21,183 expression quantitative trait loci (eQTLs) and 6,768 spl

156 like cells (HLCs) for genome-wide mapping of expression quantitative trait loci (eQTLs) and allele-sp

157 oritization of functional variants including expression quantitative trait loci (eQTLs) and disease-a

158 causative cis-regulatory variation including expression quantitative trait loci (eQTLs) and DNase I s

159 te genotypes and gene expression to identify expression quantitative trait loci (eQTLs) and find 1,69

160 unctional genes/SNPs for asthma by combining expression quantitative trait loci (eQTLs) and GWASs.

161 ividual, three-generation family to contrast expression quantitative trait loci (eQTLs) and splicing

162 lot project, we demonstrated that harnessing expression quantitative trait loci (eQTLs) and tissue-ti

163 Conditioned on a tissue, expression quantitative trait loci (eQTLs) are genetic v

164 Expression quantitative trait loci (eQTLs) are genetic v

165 Expression quantitative trait loci (eQTLs) are likely to

166 The phenotypic consequences of expression quantitative trait loci (eQTLs) are presumabl

167 tory variation, some of which corresponds to expression quantitative trait loci (eQTLs) at these loci

168 other type of motif; this is consistent with expression quantitative trait loci (eQTLs) being widely

169 To clarify whether expression quantitative trait loci (eQTLs) contribute to

170 levels in HMDP, reveals both local and trans expression Quantitative Trait Loci (eQTLs) demonstrating

171 through genome-wide association studies and expression quantitative trait loci (eQTLs) discovered in

172 ne Expression (STAGE) study, 8156 cis-acting expression quantitative trait loci (eQTLs) for 6450 gene

173 h 21 putative regulatory variants, including expression quantitative trait loci (eQTLs) for AHI1 and

174 nalized regression method that maps multiple expression quantitative trait loci (eQTLs) for all relat

175 rs3129882 and rs2395163 are expression quantitative trait loci (eQTLs) for HLA-DR an

176 ional effect on miRNA binding for cis-acting expression quantitative trait loci (eQTLs) for the corre

177 Expression quantitative trait loci (eQTLs) for the mean,

178 etic variants in 57 GWASs with 24 studies of expression quantitative trait loci (eQTLs) from a broad

179 -parametric statistical test for identifying expression quantitative trait loci (eQTLs) from genome-w

180 The mapping of expression quantitative trait loci (eQTLs) has emerged a

181 al and evolutionary genetics, and studies of expression quantitative trait loci (eQTLs) have become a

182 Local and distant expression quantitative trait loci (eQTLs) have been ide

183 About ~65% of expression quantitative trait loci (eQTLs) have primary

184 Expression quantitative trait loci (eQTLs) help to expla

185 ) of type 2 diabetes (T2D) are enriched with expression quantitative trait loci (eQTLs) identified in

186 The majority of known expression quantitative trait loci (eQTLs) impact expres

187 We mapped cis expression quantitative trait loci (eQTLs) in 13 tissues

188 e resource and produced the first catalog of expression quantitative trait loci (eQTLs) in a nonhuman

189 onnecting large-scale epigenomic profiles to expression quantitative trait loci (eQTLs) in a wide ran

190 expression 1 (PRAX1) study, we analyzed cis expression quantitative trait loci (eQTLs) in platelets

191 Analysis of expression quantitative trait loci (eQTLs) in recombinan

192 s analysis of the top signals, we identified expression quantitative trait loci (eQTLs) in whole bloo

193 ow changes in gene expression are encoded by expression quantitative trait loci (eQTLs) is a key to c

194 -discovery rates and increased the number of expression quantitative trait loci (eQTLs) mapped either

195 We utilized expression quantitative trait loci (eQTLs) mapping combi

196 nce for association with disease risk across expression quantitative trait loci (eQTLs) of a gene and

197 Expression quantitative trait loci (eQTLs) provide an or

198 Analysis of expression Quantitative Trait Loci (eQTLs) provides mode

199 The mapping of expression quantitative trait loci (eQTLs) revealed that

200 The lung expression quantitative trait loci (eQTLs) study mapped

201 nd networks, despite much effort made to map expression quantitative trait loci (eQTLs) that affect t

202 rsus TLR4-stimulated monocytes reveals 1,471 expression quantitative trait loci (eQTLs) that are uniq

203 re able to predict causal variants for these expression quantitative trait loci (eQTLs) that disrupt

204 This analysis identified six expression quantitative trait loci (eQTLs) that interact

205 f SNPs to identify a gene network along with expression quantitative trait loci (eQTLs) that perturb

206 y Cheung et al. demonstrates how to identify expression quantitative trait loci (eQTLs) underlying ge

207 We performed mapping of expression quantitative trait loci (eQTLs) with WGS and

208 polymorphism (SNP) analyses to identify cis-expression quantitative trait loci (eQTLs), and conditio

209 tween SNPs in miRNA target sites, cis-acting expression quantitative trait loci (eQTLs), and the resu

210 fluence the expression level of a gene, i.e. expression quantitative trait loci (eQTLs), can help us

211 Expression quantitative trait loci (eQTLs), genetic vari

212 edominantly cell type-specific cis and trans expression quantitative trait loci (eQTLs), including mu

213 In studies of expression quantitative trait loci (eQTLs), it is of inc

214 ciated with gene expression levels, known as expression quantitative trait loci (eQTLs), may improve

215 We define these links using expression quantitative trait loci (eQTLs), methylation

216 ribonuclease (DNase)-hypersensitivity sites, expression quantitative trait loci (eQTLs), microRNA (mi

217 e marginally associated SNPs, which are also expression quantitative trait loci (eQTLs), should carry

218 evidence of cis sQTLs but not gene-level cis expression quantitative trait loci (eQTLs), suggesting t

219 ositively selected archaic haplotypes act as expression quantitative trait loci (eQTLs), suggesting t

220 GWAS loci are also enriched in expression quantitative trait loci (eQTLs), thus suggest

221 Mapping studies for expression quantitative trait loci (eQTLs), transcriptio

222 enetic control of gene expression occurs via expression quantitative trait loci (eQTLs).

223 we identified 14 sex- and 10 age-interacting expression quantitative trait loci (eQTLs).

224 g durations of lipopolysaccharide and mapped expression quantitative trait loci (eQTLs).

225 presence of cell type-specific cis and trans expression quantitative trait loci (eQTLs).

226 ed for Arabidopsis thaliana, uncovering many expression quantitative trait loci (eQTLs).

227 terns of many genes that are associated with expression quantitative trait loci (eQTLs).

228 m (LD) annotations as well as annotations of expression quantitative trait loci (eQTLs).

229 ritability of transcription and detection of expression quantitative trait loci (eQTLs).

230 zeina infection allowed detection of 20 206 expression quantitative trait loci (eQTLs).

231 able genotype-phenotype correlations such as expression quantitative trait loci (eQTLs).

232 nts and identify over 6000 unique genes with expression quantitative trait loci (eQTLs).

233 , and TLR7/8) and influenza virus-and mapped expression quantitative trait loci (eQTLs).

234 ched for genes associated with risk loci via expression quantitative trait loci (eQTLs).

235 locations of these variants can be mapped as expression quantitative trait loci (eQTLs); however, a m

236 ncoding (such as 3'UTRs or splice sites), or expression quantitative trait loci (eQTLs; indicating th

237 discovery rate <0.05, we identified 370 cis-expression quantitative trait loci (eQTLs; SNPs associat

238 influencing skeletal muscle gene expression (expression quantitative trait loci [eQTLs]) as well as e

239 Lastly, results of a targeted islet expression quantitative trait loci experiment support th

240 morphisms in 61 patients with SCD identified expression quantitative trait loci for 103 of these hypo

241 DHS credible variants were expression quantitative trait loci for NFATC1 and RGS14

242 ate examination of linkage disequilibrium or expression quantitative trait loci for reported associat

243 nces as quantitative traits and mapping gene expression quantitative trait loci for these traits has

244 The SNPs on chromosome four were expression quantitative trait loci for TSPAN5.

245 We genotyped 408,273 SNPs and identified expression quantitative trait loci from measurements of

246 cted keratinocyte regulatory elements and in expression quantitative trait loci; furthermore, we iden

247 gh-throughput genomic techniques to map gene expression quantitative trait loci has spurred the devel

248 l genomic approaches, such as the mapping of expression quantitative trait loci, have helped to ident

249 ted on different chromosomes, and report 934 expression quantitative trait loci, identified in an ind

250 comparison subjects and identified putative expression quantitative trait loci in and around the NOT

251 SNPs defining expression quantitative trait loci in Arabidopsis promot

252 y, we assessed whether significant SNPs were expression quantitative trait loci in genome-wide expres

253 d a combined approach of mapping protein and expression quantitative trait loci in peripheral blood m

254 Finally, polymorphism studies reveal expression quantitative trait loci in the PGC-1beta gene

255 lead variants for NFAT5 and SLC4A10 are cis expression quantitative trait loci in tissues of the cen

256 Fifteen of the associated variants had expression quantitative trait loci in whole blood.

257 Analysis with expression quantitative trait loci indicated that the ri

258 ng mouse population, we show how clusters of expression quantitative trait loci linking to regions of

259 de association studies, gene expression, and expression quantitative trait loci mapping in human valv

260 2 ethnically distinct populations, cis-eQTL (expression quantitative trait loci) mapping, and functio

261 Methylation-expression quantitative trait loci (methyl-eQTL) identif

262 Identification of microRNA expression quantitative trait loci (miR-eQTL) can yield

263 Genome-wide scans for module expression quantitative trait loci (mQTLs) reveal five m

264 tions, association mapping of causal QTLs or expression quantitative trait loci must consider both ad

265 We also identified 18 genomic regions with expression quantitative trait loci of genes correlated w

266 We call these loci competing endogenous RNA expression quantitative trait loci or 'cerQTL', and foun

267 riants influencing gene expression (known as expression quantitative trait loci or eQTLs) is importan

268 extra gene dosage, we call them copy number expression quantitative trait loci, or ceQTLs.

269 ropic across cancer types, genes affected by expression quantitative trait loci, or functional genes

270 lues via data permutation, and searching for expression quantitative trait loci over thousands of gen

271 with human traits, including methylation and expression quantitative trait loci (QTL) studies.

272 ified numerous behavioral, physiological and expression quantitative trait loci (QTLs).

273 With this, cis expression quantitative trait loci signals for the same

274 g identified 110 local genetic variants (cis-expression quantitative trait loci), some of which are s

275 l SNP at the BCAR1-CFDP1-TMEM170A locus, and expression quantitative trait loci studies implicate BCA

276 n across individuals and identified a set of expression quantitative trait loci that contribute to th

277 334 F2 mice and identified more than 10,000 expression quantitative trait loci that either mapped to

278 Three of these expression quantitative trait loci were independent (not

279 c enhancer signatures as well as immune cell expression quantitative trait loci, while decreasing-lev

280 gnificant regions identified contained known expression quantitative trait loci with putative functio

281 lse discovery rate of 5% and showed that the expression quantitative trait loci with the most signifi