ライフサイエンスコーパス: extension

1 ent, indicating telomerase-mediated G-strand extension.

2 he first charged amino acid found within the extension.

3 a mechanism that is independent of lifespan extension.

4 affected mainly by the length of C-terminal extension.

5 replication and recombination-based telomere extension.

6 xtensive sliding between tissues during axis extension.

7 s and regulates telomerase-mediated telomere extension.

8 l fracture occurred in each group during the extension.

9 y a local conformational switch in a peptide extension.

10 oss of efficiency when compared to 8-oxoG:dC extension.

11 metastases, tumors 4 cm or larger, or local extension.

12 ecular mechanisms of filopodia formation and extension.

13 tructures occurs very early during flagellum extension.

14 SC) differentiation into neurons and neurite extension.

15 responding to 5- to 100-pN forces and 50-85% extension.

16 decrease in both truncal flexion and truncal extension.

17 ouble-stranded DNA with a 3' single-stranded extension.

18 se I to successfully inhibit template strand extension.

19 ur system reveals roles for glia in dendrite extension.

20 ickiness, whereas decrease the resistance to extension.

21 ercome by cellular energy input to stabilize extension.

22 ved nectar from their unique tubular nectary extensions.

23 elasticity across a broad range of relative extensions.

24 Sweden), with optional 12-month double-blind extensions.

25 lymerases perform a slippage and realignment extension across from the damaged base.

26 deficiency attenuates autophagy and lifespan extension across mechanistically distinct longevity nema

27 Here, we show that the geodetic signal of extension across the eastern Sevier Desert is best expla

28 During Drosophila embryonic axis extension, actomyosin has a specific planar-polarised or

29 H-BLAST employs a locally decoupled seed-extension algorithm for better performance on GPUs, and

30 dition as well as trimer-assisted RNA primer extension, allowing efficient copying of a variety of sh

31 g profiles representing the cumulative chain extension along the normal to the aqueous interface.

32 BPs in cultured cells, whereas this Protocol Extension also enables the identification of the RNA-bin

33 Bacteria encoding L27 with this N-terminal extension also encode a sequence-specific cysteine prote

34 y monitored reversible Von Willebrand factor extension and binding to GPIbalpha under flow.

35 emoattractant, leading to directed pseudopod extension and chemotaxis.

36 eria from young donors resulted in life span extension and delayed behavioral decline.

37 2 betaI could be uncoupled because the beta2 extension and headpiece opening could occur independentl

38 , multiplex-PCR and detection by single-base extension and MALDI-TOF mass spectrometry, in a novel me

39 via Scar/WAVE and Arp2/3 to effect pseudopod extension and migration of melanoblasts in skin.

40 structure characterization that uses barcode extension and next-generation DNA sequencing to quantita

41 ng as primers to initiate the polymerization extension and nicking endonuclease cleavage reaction.

42 This article describes an update of that extension and presents an extension for reporting abstra

43 e demonstrated roles for CHL1 in both axonal extension and repulsion, selectively of DA neurons, sugg

44 crescentus pili undergoing dynamic cycles of extension and retraction.

45 lls by controlling both leading process (LP) extension and somal translocation via distinct pathways.

46 memory transitions manifested by directional extension and subsequent retraction in polymers are attr

47 re, larger ICH, presence of intraventricular extension and use of proxy responders.

48 s meet these claims with a range of exciting extensions and applications, as well as critiques.

49 s presenting passive upstream and downstream extensions and integrated into microfluidic channels.

50 nt to the chemistry surrounding the loading, extension, and offloading of assembly lines that constru

51 involves cellular events such as convergent extension, apical constriction and interkinetic nuclear

52 ramework combined with an efficient seed-and-extension approach.

53 nimal work together; we found knee and ankle extension are the principal drivers of speed on a level

54 l method of Flanders et al. and our proposed extensions are particularly well-suited for time-series

55 Here we use Drosophila proboscis extension as a model system for a reaching-like behavior

56 with inclusion or exclusion of transosseous extension as the standard of reference.

57 lood proteins were quantified by a proximity extension assay from 266 patients at baseline and week 4

58 ought to evaluate if providing external knee extension assistance could reduce the excessive burden p

59 For six participants, powered knee extension assistance favorably reduced the excessive sta

60 ategies gave the best result (83% shelf life extension at 25 degrees C).

61 We find that a conserved peptide extension at the C-terminal end of the IgM heavy (Ig-mu)

62 matin Accessibility and Methylation), a seed-extension based approach that identifies chromatin acces

63 The strategy adopted involved pathway extension beyond beta-carotene through the expression of

64 Nutrients-and by extension biosynthetic capacity-positively impact cell s

65 SFA-1 is specifically required for lifespan extension by dietary restriction and by modulation of th

66 rescent protein abundance, and blocks primer extension by DNA polymerase, thereby demonstrating the f

67 Benefiting from the pi-conjugation extension by fusing two phenyls, IDTN shows stronger mol

68 , especially the DAF-16 cascade, on lifespan extension by LAB.

69 erase II (RNA pol II) is its long C-terminal extension, called the carboxy-terminal domain (CTD).

70 Convergent extension (CE) is a fundamental morphogenetic mechanism

71 ates and invertebrates, including convergent extension (CE).

72 rge subunit is synthesized with a C-terminal extension, cleaved off by a specific endopeptidase durin

73 ses and 1624 controls from three studies, an extension cohort of 12 577 ischaemic stroke cases and 25

74 ess associations within a family, and the RV extension combines the single-variant GDT statistic over

75 2 and half of ABS1, and present a C-terminal extension containing a proline-rich domain and an actin-

76 nary structures (hPolbeta.DNA.dNTP) for both extension contexts, wherein the incoming nucleotide is b

77 cific aptasensor was constructed based on an extension-contraction movement of DNA interconversion fo

78 A working model of nonenzymatic RNA primer extension could illuminate how prebiotic chemistry trans

79 Moreover, we found that N- and C-terminal extensions create a highly unusual all alpha-helical spl

80 The redox regulated C-terminal extension (CTE) and the associated alternate splicing me

81 s, we measured the effects of ssRNA on force extension curves for dsDNA.

82 phic and cryo-EM studies, the obtained force-extension curves on arrays with 167-bp NRLs best support

83 Force-extension curves revealed a gradient, from high to low,

84 This study assessed growth (linear extension, density, and calcification) of three branchin

85 This Protocol Extension describes the fabrication and technical proced

86 rs consists of VgrG proteins with C-terminal extension domains carrying various enzymatic activities.

87 l margins (SM negative) and no extracapsular extension (ECE).

88 ose-finding study (PACE-MDS), with long-term extension, eligible patients were aged 18 years or older

89 The extranodal extension (ENE) of nodal metastasis involves the extensi

90 eural activity to detect hypoxic and gastric extension events from the glossopharyngeal and vagus ner

91 lso amplifying product yield in single chain-extension experiments and enabling multiple chain extens

92 the workbench guarantees simple access, easy extension, flexible adaption to personal and security ne

93 The Extension for Community Healthcare Outcomes (Project ECH

94 Changes to the CONSORT Statement extension for NPT trials include wording modifications t

95 an update of that extension and presents an extension for reporting abstracts of NPT trials.

96 rescence microscopy and provides an optional extension for super-resolution imaging using stimulated

97 y convenient, and the BioNetGen package with extensions for spatial simulation, which is better for c

98 ted analogs and relies on the HPF C-terminal extension forming the binding platform for the interacti

99 A lasso extension forms an interface between SUR1 and Kir6.2 adj

100 Extension from DNA damage at primer termini remains poor

101 dium choroidal melanomas without extraocular extension from July 2012 through September 2015.

102 higher than those from the recently proposed extension GCTA-LDMS.

103 emonstrated that multifocality, extrahepatic extension, grade, node positivity, and age greater than

104 demonstrate that the eukaryote-specific RpL4 extension harbours overlapping binding sites for Acl4 an

105 Following extension, headpiece opening is energetically favored.

106 pts of solid-state metathesis and metal node extension in An-MOFs are reported, and the results of th

107 tealth family proteins revealed a C-terminal extension in CsxA, which conferred processivity because

108 ny of which have been implicated in lifespan extension in flies.

109 required the unique KIF3C-specific sequence extension in loop L11 at the microtubule interface.

110 ctions and planar polarity during convergent extension in the Drosophila embryo.

111 s the length of stay in the dwelling and, by extension, in the local labor and housing markets.

112 Polymer extension, interdigitation, and grafting density are det

113 pen the F pocket and expose their C-terminal extension into the solvent.

114 on the head and neck, where clinical occult extension is common, were studied at an academic medical

115 291-1302-amino acid region of the C-terminal extension is critical for relieving the auto-inhibition

116 by RNA/DNA triplex-formation, and that dsDNA extension is impeded by formation of RNA secondary struc

117 Extension is largest in small pores, increasing >10-fold

118 lationship to 5' end resection and/or 3' end extension is poorly understood.

119 Accordingly, the observed lifespan extension is prevented on a high-protein diet and in Fox

120 We show that hydralazine-mediated lifespan extension is SKN-1 dependent, with a mechanism most like

121 t to explore experimentally as their spatial extension is very small, a few molecular lengths in the

122 a patient's cancer drive its biology and, by extension, its clinical features and treatment response.

123 t such front is associated with the Kuroshio Extension (KE) as it extends east of Japan ("upstream KE

124 wi-interacting RNA intermediates with 3' end extension, leading to severe reduction of mature piwi-in

125 2C-)12] carboxylate-based cluster, points of extension matching the 12 vertices of hexagonal-prism d6

126 We uncover a retrograde extension mechanism for axon growth, and reveal the aeti

127 , that is, benefits of success, but lifespan extension might expand disability of physical and cognit

128 lly inactivated in the dehydratase domain of extension-module 1 showed that this module catalyzes two

129 yces sp. 211726 has shown that only nineteen extension modules are required to accomplish twenty cycl

130 y, corresponding to a mean decline in linear extension of -29.56 cm yr(-1) (+/-7.08 SE), which accoun

131 dent nucleotidyl transferase reaction during extension of a DNA strand using the complementary strand

132 lation prior to editing, and by post-editing extension of a short A-tail into a long A/U-heteropolyme

133 hanced perceptual performance, we propose an extension of a simple and influential model in which shi

134 his proof-of-concept dynamic NA method is an extension of a state-of-the-art static NA method, MAGNA+

135 us attempt, we show that a remarkably simple extension of a two-state model, initially developed to r

136 ant roles in functional axogenesis by proper extension of axon as well as the formation of AIS during

137 The C-terminal extension of capsid protein VP3 folds into a globular pr

138 Over-extension of contigs without prior knowledge of contig l

139 PEC activation and reduce the frequency and extension of crescents in extracapillary GN.

140 volumetric hydrogel expansion by successive extension of cross-links.

141 Its neurons have bipolar extension of dendrites, which receive segregated inputs

142 However, the extension of DGT to a wide range of analytes and its use

143 the search dynamics depends on the degree of extension of DNA molecules and on the size of RecA nucle

144 eoretical and mathematical model based on an extension of evolutionary game theory on networks (EGN),

145 e validated computational results through an extension of Flux Balance Analysis that allows predictio

146 es in the D-loop region are generated by the extension of H-strand transcripts beyond their canonical

147 ables improved detection of the transosseous extension of intracranial meningiomas compared with CE-M

148 e improvements of this method, as well as an extension of its applications to other modeling methods

149 ed to enable exclusion of any extramedullary extension of leukemia.

150 pathways and small molecules associated with extension of lifespan in diverse organisms.

151 actor-driven PI3K signaling, contributing to extension of lifespan, cardioprotection, and tumor inhib

152 inally, we find that deleting the C-terminal extension of Lmod1 and Lmod2 results in an approximately

153 h hormone (GH) action can produce remarkable extension of longevity in mice.

154 testing for the gene sets is performed by an extension of Mann-Whitney U test which is based on weigh

155 ced delivery method, which shows significant extension of median survival in two patient-derived BTIC

156 Expression of the K2 C terminus as an extension of membrane-anchored P-selectin glycoprotein l

157 Patients with transosseous extension of meningioma (n = 67) showed significantly la

158 nsion (ENE) of nodal metastasis involves the extension of neoplastic cells through the lymph node cap

159 Moreover, the extension of optimal Bayesian classification to multinom

160 Extension of our findings via modeling of degassing tren

161 These methods are an extension of our previously developed method for purity

162 PERFILAR II was an extension of PERFILAR I with additional allergens being

163 The extension of phosphatidylserine externalization was slow

164 Ras and associated F-actin that precede the extension of protrusions.

165 Hg-based probes allow the extension of SECM investigations to ionic processes, but

166 to understanding early CAVD and envision the extension of such models to investigate other tissue pat

167 The method comes as an extension of the calculation methods (soliton gates) as

168 The retina as an extension of the diencephalon accessible to in vivo micr

169 Moreover, extension of the digit rays and the patterning of the jo

170 sis, which suggests that wings evolved as an extension of the dorsal thorax, and the gill-exite hypot

171 effects of overlapping genes by a functional extension of the elastic-net regression.

172 Volume was also conserved following uniaxial extension of the FN nanofibers of 2-fold relative to th

173 lti-compartment muscle that allows dexterous extension of the four digits.

174 m clinical trials and the anticipated future extension of the global platform to non-clinical trial d

175 eeth form due to defects in the direction of extension of the HERS from the crown, associated with a

176 copic analysis indicated that the C-terminal extension of the large subunit is essential for recognit

177 2 months of avoiding peanuts in the 12-month extension of the LEAP study (LEAP-On).

178 ting T lymphocytes and results in a profound extension of the median survival of treated animals.

179 Myelin in the CNS is a specialised extension of the oligodendrocyte plasma membrane and cle

180 The hardware is an extension of the Open AUC MWL detector developed in acad

181 h beta-N-acetylglucosaminidase and selective extension of the other arms.

182 Extension of the PSF framework to the phyllosphere is ne

183 Extension of the serum half-life is an important issue i

184 characteristics, but MOST-Visualization, an extension of the software package MOST (Metabolic Optimi

185 An extension of the tandem coupling/4pi-electrocyclization

186 nnel and the acoustic trachea as well as the extension of the tectorial membrane are not correlated t

187 ture works well for a reliable and automatic extension of the terminology.

188 This paper presents TurboFold II, an extension of the TurboFold algorithm for predicting seco

189 Together, extension of these clinical, pathologic, and genetic ass

190 rodent and human immune physiology limit the extension of these findings to our understanding of huma

191 A logical extension of this framework is that regulatory standards

192 Here we report on a powerful extension of those modes, "ringing" mode, which more tha

193 No iatrogenic extension of tumor was reported.

194 The aim of this study was the shelf life extension of whole-wheat breadsticks through the additio

195 As an extension of wide-field fluorescence microscopy, it is i

196 Extension of work based on these understandings leads to

197 ming off appropriate regions of the terminal extensions of Drs2p can greatly increase its ATPase acti

198 n also be predicted with high accuracy using extensions of existing techniques, but protein-protein a

199 wo of these laws can be regarded as rigorous extensions of previously known laws: One gives a modal v

200 psid morphology that contains more prominent extensions of protein IX and can replicate efficiently i

201 However, there have been few extensions of the drift-diffusion model to the Simon eff

202 Both are extensions of the Minimum Information about Any (x) Sequ

203 rmal development and tissue homeostasis, are extensions of the mother centriole, but the mechanisms t

204 to the duration of individual buzzes and (2) extensions of the overall time spent buzzing.

205 Primary cilia are hairlike extensions of the plasma membrane of most mammalian cell

206 As root hairs are single-cell extensions of the root epidermis and the primary organs

207 These results demonstrate how extensions of these methods to other goals and data can

208 VP2, the GH loop of VP3, and the N-terminal extensions of VP1 and VP2, which, in retrospect, were pr

209 ent trials) and the first year of open-label extension (OLE) trials that included a standard-of-care

210 cts induced by such alpha-synuclein sequence extension on alpha-synuclein aggregation propensity are,

211 These results allow for an extension on the definition of bacterial PUL-mediated po

212 To investigate the effect of NTR extensions on the enzymatic behavior of individual isofo

213 es to the otherwise divergent amino-terminal extensions on these pollen sPPases.

214 le, either phosphorylation of its N-terminal extension or DNA binding promotes the formation of phase

215 structure of the human telomerase C-terminal extension (or thumb domain) determined by the method of

216 into ARIEL2 Part 1 is complete, although an extension (Part 2) is ongoing.

217 ported here) for 12 weeks, and an open-label extension (part 3).

218 through these artificial linkages by primer extension, PCR, and deep sequencing reveals that a subtl

219 Knee-extension peak power was also differently affected (P =

220 Knee-extension peak power was measured with dynamometry.Both

221 uld also participate in an 8-week open-label extension period.

222 nalysis period, patients entered a long-term extension phase in which all received eliglustat.

223 t change of either hand grip strength or leg extension power.

224 up-regulated and negative regulation of axon extension processes were down-regulated at 3 h.

225 e cell elongation, intercalation, convergent extension, proliferation, and differentiation.

226 ring (SAXS) results show that the N-terminal extensions protrude from the spherical shell of both pro

227 anomalous heat in the Gulf Stream's northern extension provides predictability of northwestern Europe

228 Geologic extension rates of c. 0.6 mm yr(-1) over the last c. 50

229 This is achieved by combining the oligo extension reaction (OER), which converts protein levels

230 ction kinetics and improved yields of primer extension reaction products.

231 he model exhibits two distinct, linear force-extension regimes, with the response to small tensions g

232 The overall decrease in efficiency of extension relative to 8-oxoG bypass is due to an alterna

233 bbons in solution and found that the lateral extension results in decrease of their electronic bandga

234 tability of the ternary complex of 8-oxoG:dA extension results in further loss of efficiency when com

235 elementary step of contraction is sequential extension-retraction of platelet filopodia attached to f

236 Follow-up of patients during the open-label extension revealed no new safety signals and suggested s

237 ely hydrated asthenosphere, and concentrated extension (rift necking) near the central TAM range fron

238 The dependence of DHX36 on the 3'-extension sequence suggests that the extent of formation

239 tive 2-hydroxyl acylation analyzed by primer extension sequencing (SHAPE-Seq) to simultaneously probe

240 PRINCESS leverages Software Guard Extensions (SGX) and hardware for trustworthy computatio

241 pt selective 2'-hydroxyl acylation by primer extension (SHAPE) chemical probing, we show that splicin

242 ive 2'-hydroxyl acylation analyzed by primer extension (SHAPE) RNA structure probing.

243 ipulations during naturally evoked proboscis extension show that orchestration of serial motoneuron a

244 pes of modules distinguished by unique force-extension signatures.

245 monomers and the template is observed at the extension site and at the adjacent downstream position.

246 usly in ensheathing glia to regulate process extension so as to insulate each neuropil compartment.

247 Poltheta carries out both the insertion and extension steps of TLS opposite 3-dMeA, and in the Polze

248 The phase 3 study and subsequent extension study clarified that the decrease in MMP-9 lev

249 study involving 186 patients; an open label extension study performed after the phase 3.

250 nroll in an observational, noninterventional extension study to collect retrospectively and prospecti

251 were maintained through M12 of the ENDURANCE extension study with a reduced treatment frequency, with

252 rder to be considered for enrolment into the extension study.

253 Phase IV, multicenter, open-label extension study.

254 ganotypic bronchiole, we present a clickable extension that facilitates volatile compound communicati

255 an approximately 170-residue-long N-terminal extension that structurally mimics a dimer-dimer interfa

256 A-binding tunnel with a separate hydrophobic extension that unexpectedly engages the cap in multiple

257 The binding of pVIIn2-and, by extension, that of genome-condensing pVII-to hexons is c

258 income variability, financial risk, and, by extension, the economic stability and the sustainable us

259 As a protocol extension, this article describes an adaptation to our e

260 nd both may play a critical role in lifespan extension through insulin signaling.

261 d cross-platform, and can be installed as an extension to 3D Slicer (www.slicer.org).

262 erating system, as a Docker image, and as an extension to 3D Slicer.

263 of multiple hypervalence, has potential for extension to a broader range of solid-state compounds.

264 ng's moduli ranging from 1.8 to 13.2 MPa and extension to failure exceeding 250% over a range of stra

265 Extension to flexible fibre-based systems is clinically

266 This represents a significant extension to our previously developed algorithms to pred

267 rotective T-cell target antigens, precluding extension to PIV3.

268 Our model is a multidimensional extension to signal detection theory that distinguishes

269 tation were compared using the Andersen-Gill extension to the Cox proportional hazards model while ac

270 th these findings, including 1 with visceral extension to the spleen.

271 In an extension to the trial, participants were offered 1 year

272 in freely moving rodents.This protocol is an extension to: Nat.

273 Results of extensive characterizations, extensions to 2D and 3D trajectories, and applications t

274 sion experiments and enabling multiple chain extensions to form multiply fluorinated products.

275 m vaccination strategies for influenza, with extensions to make it easily adaptable to other diseases

276 d identification assumptions prohibit simple extensions to settings with multiple mediators that may

277 tegies for maximising pollen collection: (1) extensions to the duration of individual buzzes and (2)

278 Extensions to these models are required to quantify the

279 hanical balance, guides the flow and orients extension towards the posterior end.

280 This ongoing, randomized open-label extension trial (OSLER-1) was conducted at 192 sites in

281 rial were included in this 2-year open-label extension trial (RAPID-OLE).

282 he framework nodes (type I), (ii) metal node extension (type II), and (iii) metal coordination to the

283 how structural inheritance and variations in extension velocity control the architecture of rifted ma

284 Lifespan extension via the suppression of IGF-1/insulin-like sign

285 During filopodia extension, we found the translocation of Arp2/3 and inte

286 nravel the functional role of the C-terminal extension, we used an enzymatic in vitro maturation assa

287 ne in ppFEV1 was 0.5 (95% CI -0.4 to 1.5) at extension week 72 and 0.5 (-0.7 to 1.6) at extension wee

288 96; change in BMI was 0.69 (0.56 to 0.81) at extension week 72 and 0.96 (0.81 to 1.11) at extension w

289 ate in patients continuing treatment through extension week 96 (0.65, 0.56 to 0.75) remained lower th

290 extension week 72 and 0.96 (0.81 to 1.11) at extension week 96.

291 t extension week 72 and 0.5 (-0.7 to 1.6) at extension week 96; change in BMI was 0.69 (0.56 to 0.81)

292 of investigational product in FREEDOM or the extension were included in the combined safety analyses.

293 set of tools integrated in a single 3DSlicer extension, which aims to assist neurosurgeons in the ana

294 inding was not affected by cry1's C-terminal extension, which is important for signal transduction.

295 arge, >130 A length-scale change in integrin extension, which is well tailored to match the free-ener

296 n, through the interaction of its N-terminal extension with actin and its C-terminal lobe with the my

297 ntly to a change of mechanism in which chain extension with fluorine-substituted extender units switc

298 All participants who enrolled in the extension with observed data were included in the effica

299 channel of the enzyme, thereby allowing RNA extension without displacement of the promoter recogniti

300 nsive scale-up of the availability of health extension workers (HEWs) at the community level has been

301 l reconstructions of nonenzymatic RNA primer extension yield a mixture of 2'-5' and 3'-5' internucleo