ライフサイエンスコーパス: extracellular signal

1 atty acids can act as both intracellular and extracellular signals.

2 les responsible for receiving and processing extracellular signals.

3 g of gene activation in response to specific extracellular signals.

4 verned by the inputs of intracellular and/or extracellular signals.

5 as the ability to record fast components of extracellular signals.

6 gen-activated kinase (MAPK) that responds to extracellular signals.

7 ons that presumably differentially integrate extracellular signals.

8 s that modulate cell motility in response to extracellular signals.

9 cellular electrical activity in response to extracellular signals.

10 mework that is responsive to a wide range of extracellular signals.

11 We found that extracellular signals affect the behavior of the agr bim

12 Extracellular signaling and DNA-binding transcription fa

13 lls to proliferate, differentiate, transduce extracellular signals and assemble tissues involves stru

14 anscriptional regulatory networks respond to extracellular signals and mechanical stimuli.

15 tion or tissue repair is directed by various extracellular signals and mediated by multiple intracell

16 most cells, are important to the sensing of extracellular signals, and make a driving force for flui

17 ube growth through the pistil in response to extracellular signals, and regulate the actin cytoskelet

18 Signal-transduction pathways regulated by extracellular signals are coupled to distinct sets of br

19 During development, extracellular signals are integrated by cells to induce

20 Extracellular signals are often transduced by dynamic si

21 Extracellular signals are transduced to the cell nucleus

22 can modulate Notch1 activity in response to extracellular signals by mobilizing Notch1 from endosoma

23 ry mechanisms governing cell fate decisions, extracellular signaling, cell and tissue organization, a

24 hways is required to integrate the myriad of extracellular signal combinations at the cellular level.

25 II pause release and the mechanisms by which extracellular signals control it are incompletely unders

26 Transcriptional networks, regulated by extracellular signals, control cell fate decisions and d

27 GnRH) represents a longstanding puzzle about extracellular signal decoding mechanisms.

28 The cilium's capacity to sense and transduce extracellular signals depends on dynamic trafficking of

29 e repressor operates in clusters, which upon extracellular signal detection, translocate from the cyt

30 lcium entry (SOCE) is the mechanism by which extracellular signals elicit prolonged intracellular cal

31 e (NAD(+)) participates in intracellular and extracellular signaling events unrelated to metabolism.

32 of integral membrane proteins that transduce extracellular signals from a wide range of agonists into

33 re largely governed by the interplay between extracellular signals from the niche and the cell intrin

34 The major sperm protein domain (MSPd) has an extracellular signaling function implicated in amyotroph

35 ellular housekeeping function, as well as an extracellular signaling function mediated by the secrete

36 In three datasets examining the impact of extracellular signals, genes responsive to stimulus have

37 A screen of pancreatic extracellular signals identified factors that stimulated

38 Here, we review the role of extracellular signals in guiding stem cell behavior via

39 r transcription factor activated by multiple extracellular signals including growth factors and hormo

40 ivated by oxidative stress and several other extracellular signals including tumour necrosis factor a

41 se 'WalK' (erWalK) as a key hub for bridging extracellular signal input and intracellular kinase acti

42 cessing modulates single-cell sensitivity to extracellular signaling inputs, including those guiding

43 esized that these clusters convert an analog extracellular signal into a digital intracellular signal

44 ptors (GPCRs) are essential for transferring extracellular signals into carefully choreographed intra

45 unction mutations in ELMO2 (which translates extracellular signals into cellular movements) that are

46 used in many systems for the transduction of extracellular signals into the expression of signal-resp

47 The transmission of extracellular signals into the nucleus involves inducibl

48 F-kappaB) pathway, which integrates multiple extracellular signals into transcriptional programs for

49 y of newly synthesized GPCRs is regulated by extracellular signals is less understood.

50 Adenosine, a key extracellular signaling mediator, regulates several aspe

51 Previous studies have implicated the extracellular signaling molecule adenosine and signaling

52 This extracellular signaling molecule is a strong chemoattrac

53 pe 1 (LPA1) is 1 of 6 known receptors of the extracellular signaling molecule lysophosphatidic acid.

54 an intracellular protein modifier and as an extracellular signaling molecule that stimulates IFN-gam

55 Quorum sensing relies on extracellular signal molecules and cognate receptor pair

56 ction, detection, and group-wide response to extracellular signal molecules called autoinducers.

57 bacteria communicate with one another using extracellular signal molecules called autoinducers.

58 eproductive tissues, which are controlled by extracellular signaling molecules interacting with recep

59 It has been suggested that extracellular signaling molecules with different diffusi

60 indicated that AGR2 directly binds to these extracellular signaling molecules, and enhances their ho

61 iphosphate (UTP), among others, may serve as extracellular signaling molecules.

62 perties of the cell wall and the activity of extracellular signaling molecules.

63 m that directly links the secreted AGR2 with extracellular signaling networks, and we propose that th

64 The effects of soluble extracellular signals on these cellular functions are fa

65 Elimination of any single extracellular signaling pathway only delays but does not

66 Our findings support an emerging view that extracellular signalling pathways are crucially required

67 Subsequently, self-generated extracellular signals provide morphological cues that re

68 cates that CitK integrates intracellular and extracellular signals provided by the local environment

69 egulatory mechanism, the role of this TCS in extracellular signal recognition and factors that modula

70 gonistic activity for Galphai activation and extracellular signal regulated kinase (ERK) 1/2 phosphor

71 ed protein kinase C (PKC) in the cytosol and extracellular signal regulated kinase (ERK) in the cytos

72 ng MAPK inhibitors reveal that inhibition of extracellular signal regulated kinase (ERK) protects ETO

73 Here we address this question for extracellular signal regulated kinase (Erk) signaling, a

74 alized at 24 h, while the phosphorylation of extracellular signal regulated kinase (ERK) was increase

75 p1 to rapidly and RAR-independently activate extracellular signal regulated kinase 1/2 (ERK1/2).

76 s and sAC is required for the acute phase of extracellular signal regulated kinase 1/2 activation tri

77 reased phosphorylation level of both Src and extracellular signal regulated kinase proteins and with

78 Over expression of extracellular signal regulated kinases (ERK) pathway pla

79 cardiovascular disease, is known to activate extracellular signal regulated kinases 1 and 2 (ERK1/2).

80 mFFA4 but did not limit receptor coupling to extracellular signal regulated protein kinase 1 and 2 (E

81 deficiencies, as well as phosphorylation of extracellular-signal regulated kinase 1/2 (ERK1/2).

82 2) (COT, MAP3K8) kinase activates the MEK1/2-extracellular-signal regulated kinase 1/2 MAP kinase sig

83 s phospho-Ser10-histone H3 without modifying extracellular-signal regulated kinase phosphorylation in

84 m after acute cocaine administration, via an extracellular-signal regulated kinase-dependent de novo

85 To test the role of extracellular-signal regulated kinases 1 and 2 (ERK1/2)

86 Evidence demonstrates that extracellular signal-regulated kinase (ERK 1/2) activati

87 Inhibiting p38 MAPK or extracellular signal-regulated kinase (ERK) 1/2 MAPK (up

88 y upregulated, but uncoupled from downstream extracellular signal-regulated kinase (ERK) 1/2 signalin

89 ly localized D2R long isoform (D2LR) elicits extracellular signal-regulated kinase (ERK) activation a

90 Temporal inhibition of extracellular signal-regulated kinase (ERK) activation b

91 d the dynamics of protein kinase C (PKC) and extracellular signal-regulated kinase (ERK) activation d

92 ositide 3-kinase (PI3Kgamma) plays a role in extracellular signal-regulated kinase (ERK) activation f

93 ctivation of S6K1 during extinction required extracellular signal-regulated kinase (ERK) activation i

94 RCC induced paracrine extracellular signal-regulated kinase (ERK) activation i

95 ained intracellular calcium mobilisation and extracellular signal-regulated kinase (Erk) activation,

96 duced two mechanistically distinct phases of extracellular signal-regulated kinase (ERK) activation,

97 p4k4 silencing in ECs enhanced basal Ras and extracellular signal-regulated kinase (Erk) activities,

98 Although deregulation of MEK/extracellular signal-regulated kinase (ERK) activity is

99 ) and E-prostanoid receptor (EP) 3, enhanced extracellular signal-regulated kinase (Erk) and c-fos ph

100 well as downstream pathways including STAT5, extracellular signal-regulated kinase (Erk) and p38.

101 bition of PDE1 caused greater stimulation of extracellular signal-regulated kinase (ERK) and prolifer

102 Extracellular signal-regulated kinase (ERK) and protein

103 rosarcoma cells naturally expressing mutated extracellular signal-regulated kinase (ERK) antigen, the

104 ifferentiation through its activation of the extracellular signal-regulated kinase (ERK) cascade.

105 ifferentiation through its activation of the extracellular signal-regulated kinase (ERK) cascade.

106 It recruits and regulates activity of an extracellular signal-regulated kinase (ERK) cascade.

107 ired activation of nuclear factor kappaB and extracellular signal-regulated kinase (ERK) in monocytes

108 ternalization of NK-1 and phosphorylation of extracellular signal-regulated kinase (ERK) in superfici

109 patial memory depends on rapid activation of extracellular signal-regulated kinase (ERK) in the dorsa

110 by combined treatment with rapamycin and an extracellular signal-regulated kinase (ERK) inhibitor.

111 Preclinical studies suggest that extracellular signal-regulated kinase (ERK) inhibitors a

112 eleasing hormone (GnRH) receptors (GnRHR) to extracellular signal-regulated kinase (ERK) or nuclear f

113 Mechanistically, LMP1 triggered the extracellular signal-regulated kinase (ERK) pathway and

114 and migration of human keratinocytes through extracellular signal-regulated kinase (ERK) phosphorylat

115 Appropriate activation of the Ras/extracellular signal-regulated kinase (ERK) protein sign

116 ellular signal-regulated kinase kinase (MEK)/extracellular signal-regulated kinase (ERK) scaffold, ki

117 Deregulated extracellular signal-regulated kinase (ERK) signaling dr

118 o the constitutive activation of the RAF-MEK-extracellular signal-regulated kinase (ERK) signaling pa

119 tations in the genes involved in the RAF/MEK/extracellular signal-regulated kinase (ERK) signaling pa

120 uclear factor (NF) kappaB signaling, whereas extracellular signal-regulated kinase (ERK) signaling wa

121 The Emax of Galphai/o-dependent extracellular signal-regulated kinase (ERK) signaling wa

122 ge interactions in driving cAMP, calcium, or extracellular signal-regulated kinase (ERK) signaling.

123 4 resistance to NB cells through upregulated extracellular signal-regulated kinase (ERK) signaling.

124 Fibroblast growth factor (FGF)-extracellular signal-regulated kinase (ERK) signalling i

125 Here, we adapt the first-generation KTR for extracellular signal-regulated kinase (ERK) to allow eas

126 of NF-kappaB, c-Jun N-terminal kinase (JNK), extracellular signal-regulated kinase (ERK), and Akt (oc

127 e mitogen-activated protein kinases (MAPKs), extracellular signal-regulated kinase (ERK), c-JUN N-ter

128 ulin signaling/glucose homeostasis (ie, Akt, extracellular signal-regulated kinase (ERK), P70S6K), as

129 n of mitogen-activated protein kinase (MAPK)/extracellular signal-regulated kinase (ERK), PI3K/AKT, a

130 ream mitogen-activated protein kinase (MAPK)-extracellular signal-regulated kinase (ERK)-cFos pathway

131 enosine monophosphate (cAMP)-independent and extracellular signal-regulated kinase (ERK)-dependent pa

132 ampal-dependent memory by rapidly activating extracellular signal-regulated kinase (ERK)-dependent si

133 FGF19 activates the mTORC1-p70S6K and extracellular signal-regulated kinase (Erk)-p90RSK pathw

134 es apoptosis through increased activation of extracellular signal-regulated kinase (ERK).

135 integrin-mediated phosphorylation of Src and extracellular signal-regulated kinase (ERK).

136 , p21-activated protein kinases (PAK1/2) and extracellular signal-regulated kinase (ERK)/C-Jun N-term

137 n development and to differentially regulate extracellular signal-regulated kinase (ERK)/mitogen-acti

138 activated protein kinase kinase (MEK1/2) and extracellular signal-regulated kinase (ERK1/2) activatio

139 thways like mitogen-activated protein kinase-extracellular signal-regulated kinase (MAPK-Erk) signali

140 kout, while mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/ERK) and non

141 ppaB kinase (IKK), mitogen-activated protein extracellular signal-regulated kinase (MEK), and Jun N-t

142 ), such as high expression of phosphorylated extracellular signal-regulated kinase (pERK) and reduced

143 Extracellular signal-regulated kinase 1 (ERK1), a member

144 kinase 1 (MAP2K1), the gene that encodes MAP-extracellular signal-regulated kinase 1 (MEK1).

145 e to PDGF-BB, and reduced phosphorylation of extracellular signal-regulated kinase 1 and 2, Elk-1, p3

146 cell activation, as well as inflammasome and extracellular signal-regulated kinase 1 and 2-mediated n

147 d transient IkappaBalpha phosphorylation and extracellular signal-regulated kinase 1/2 (ERK1/2) activ

148 ted alpha2B-AR-mediated signaling, including extracellular signal-regulated kinase 1/2 (ERK1/2) activ

149 we previously discovered abnormally elevated extracellular signal-regulated kinase 1/2 (ERK1/2) activ

150 that NPNT stimulates the phosphorylation of extracellular signal-regulated kinase 1/2 (ERK1/2) and p

151 Previous studies have shown that extracellular signal-regulated kinase 1/2 (ERK1/2) direc

152 Recent work suggested that the activity of extracellular signal-regulated kinase 1/2 (ERK1/2) is in

153 n target of rapamycin complex 1 (mTORC1) and extracellular signal-regulated kinase 1/2 (ERK1/2) pathw

154 s found to be dependent on activation of the extracellular signal-regulated kinase 1/2 (ERK1/2) signa

155 U50,488H-induced activation of extracellular signal-regulated kinase 1/2 (ERK1/2) was G

156 ogen-activated protein (MAP) kinases p38 and extracellular signal-regulated kinase 1/2 (ERK1/2), and

157 the eIF4E upstream kinase) or inhibitors of extracellular signal-regulated kinase 1/2 (ERK1/2), the

158 iptolide binds to and activates p38alpha and extracellular signal-regulated kinase 1/2 (ERK1/2), whic

159 asmin generation, but instead is mediated by extracellular signal-regulated kinase 1/2 (ERK1/2)-regul

160 only combined treatment of mitogen-activated extracellular signal-regulated kinase 1/2 (MEK1/2) and S

161 C cells and resulted in potent inhibition of extracellular signal-regulated kinase 1/2 activation.

162 -mediated signalling pathway, including p38, extracellular signal-regulated kinase 1/2 and c-Jun N-te

163 ulated PgLPS-mediated phosphorylation of the extracellular signal-regulated kinase 1/2 and c-Jun N-te

164 on of GluN2B and inactivation of the kinases extracellular signal-regulated kinase 1/2 and Fyn.

165 cKL + FGF23 increased the phosphorylation of extracellular signal-regulated kinase 1/2 and induced Fg

166 hosphates) in some signaling events, such as extracellular signal-regulated kinase 1/2 and label free

167 s down-regulated, followed by an increase in extracellular signal-regulated kinase 1/2 phosphorylatio

168 ells, Ptges expression was regulated through extracellular signal-regulated kinase 1/2 phosphorylatio

169 eased p38 mitogen-activated protein kinases, extracellular signal-regulated kinase 1/2 phosphorylatio

170 inhibiting cAMP accumulation and activating extracellular signal-regulated kinase 1/2 signaling whil

171 ayed rapid increases in activated STAT1/3/5, extracellular signal-regulated kinase 1/2, AKT, CREB, an

172 es and were associated with an activation of extracellular signal-regulated kinase 1/2, and ribosomal

173 ory effects, increased inhibition of phospho-extracellular signal-regulated kinase 1/2, increased mit

174 ng MMP-9 secretion through the activation of extracellular signal-regulated kinase 1/2, p38, phosphoi

175 down resulted in decreased levels of phospho-extracellular signal-regulated kinase 1/2, phospho-c-Jun

176 ncluding retrovirus-associated DNA sequences/extracellular signal-regulated kinase 1/2, phosphoinosit

177 Strategies to inhibit extracellular signal-regulated kinase 1/2, ribosomal S6

178 STAT3, which is significantly enhanced by an extracellular signal-regulated kinase 1/2-dependent mTOR

179 els of phosphorylated IkappaBalpha, Akt, and extracellular signal-regulated kinase 1/2; nuclear trans

180 f miR-494 as a result of the inactivation of extracellular signal-regulated kinase 2 (ERK2), in turn

181 cents, phosphorylation of the trkB substrate extracellular signal-regulated kinase 42/44 (ERK42/44) i

182 thrombosis by increasing activation of MAPK extracellular signal-regulated kinase 5 (ERK5), a protei

183 the mitogen-activated protein (MAP) kinase (extracellular signal-regulated kinase [ERK]) signaling c

184 -containing phosphatase [p-SHP2] and phospho-extracellular signal-regulated kinase [p-ERK]) is associ

185 Spine growth required extracellular signal-regulated kinase activation, while

186 ) and lesser increases in phosphorylation of extracellular signal-regulated kinase and AK straining t

187 tyrosine phosphorylation and its downstream extracellular signal-regulated kinase and AKT phosphoryl

188 oncomitant down-regulation of phosphorylated extracellular signal-regulated kinase and myeloid cell l

189 orters, mRNAs, signaling (phosphorylation of extracellular signal-regulated kinase and phospholamban)

190 mitogen-activated protein kinase/extracellular signal-regulated kinase blockade attenuate

191 cal analysis of the MAP2K1 downstream target extracellular signal-regulated kinase demonstrated its p

192 nib and the mitogen-activated protein kinase/extracellular signal-regulated kinase inhibitor selumeti

193 al that the mitogen-activated protein kinase/extracellular signal-regulated kinase inhibitor trametin

194 ed BRAF and mitogen-activated protein kinase/extracellular signal-regulated kinase inhibitor treatmen

195 phosphatase receptor type J (PTPRJ), a known extracellular signal-regulated kinase inhibitor.

196 that the Ras/Raf/mitogen-activated protein, extracellular signal-regulated kinase kinase (MEK)/extra

197 ) induction by the mitogen-activated protein/extracellular signal-regulated kinase kinase inhibitor P

198 y niches counteracts combined BRAF/MEK (MAPK/extracellular signal-regulated kinase kinase) inhibitor

199 dependency on the mitogen-activated protein/extracellular signal-regulated kinase kinase-Erk1/2(MAPK

200 6 on both MEK-ERK (mitogen-activated protein/extracellular signal-regulated kinase kinase-extracellul

201 MAPK pathways in yeast and in the mammalian extracellular signal-regulated kinase MAPK pathway.

202 MP1 protein levels through activation of the extracellular signal-regulated kinase mitogen-activated

203 inal kinase (JNK) and c-Jun signals, but not extracellular signal-regulated kinase or Akt pathway act

204 ls a new functional role for cocaine-induced extracellular signal-regulated kinase pathway independen

205 rvival signaling pathways, including the MEK-extracellular signal-regulated kinase pathway.

206 Furthermore, miR-4443 regulated extracellular signal-regulated kinase phosphorylation an

207 stress (S-SDS) induces D1 receptor-mediated extracellular signal-regulated kinase phosphorylation an

208 vemurafenib (480 mg/d) completely abrogated extracellular signal-regulated kinase phosphorylation of

209 the amygdala [CeA]) PACAP immunoreactivity, extracellular signal-regulated kinase phosphorylation, a

210 FSTL1 blocks Wnt7a-mediated repression of extracellular signal-regulated kinase phosphorylation, e

211 hibition of mitogen-activated protein kinase/extracellular signal-regulated kinase signaling 6 hours

212 ndocytosis to block endosomal PACAP receptor extracellular signal-regulated kinase signaling attenuat

213 se/AKT, and mitogen-activated protein kinase/extracellular signal-regulated kinase signaling in mutat

214 Instead, enhanced phosphorylated extracellular signal-regulated kinase signaling in Wolff

215 The mitogen-activated protein kinase/extracellular signal-regulated kinase signaling pathway

216 carcinoma development through activation of extracellular signal-regulated kinase signaling.

217 NF release and tropomyosin receptor kinase B-extracellular signal-regulated kinase signaling.

218 nd clearance by alveolar macrophages through extracellular signal-regulated kinase signaling.

219 B cells from tolerant recipients had reduced extracellular signal-regulated kinase signalling after B

220 eton by dephosphorylating eplin at two known extracellular signal-regulated kinase sites, serine 362

221 Mechanistically, reactive oxygen species and extracellular signal-regulated kinase were found to medi

222 sympathetic nerves increase endothelial ERK (extracellular signal-regulated kinase) activity via adre

223 ERK (extracellular signal-regulated kinase) and mTOR (mechani

224 extracellular signal-regulated kinase kinase-extracellular signal-regulated kinase) and S6K-RPS6 (rib

225 Of note, a phosphorylated extracellular signal-regulated kinase+/BCL-XL(+) /myeloi

226 levels for the phosphorylated forms of AKT, extracellular signal-regulated kinase, p38, STAT1, and S

227 of K-Ras effectors, including phosphorylated extracellular signal-regulated kinase, phosphorylated pr

228 atidylinositol 3-kinase-Akt, Ras-Raf-1, MEK1/extracellular signal-regulated kinase, sphingolipid, and

229 that TRAF1 is required for solar UV-induced extracellular signal-regulated kinase-5 (ERK5) phosphory

230 1P receptor 3 (S1pr3) through Rho kinase and extracellular signal-regulated kinase-dependent pathway.

231 kinase interacting kinase-1, downstream from extracellular signal-regulated kinase.

232 loss of DAB2IP results in the activation of extracellular signal-regulated kinase/RSK1 and phosphoin

233 y inhibitors of the prolyl isomerase Pin1 or extracellular signal-regulated kinases (ERK) 1/2 or by p

234 helerythrine chloride suppressed the induced extracellular signal-regulated kinases (ERK) activity an

235 (JNK), the Axl receptor tyrosine kinase and extracellular signal-regulated kinases (ERK).

236 Here, we show that extracellular signal-regulated kinases (ERK1/2) respond

237 ting these effects, levels of phosphorylated extracellular signal-regulated kinases (pERK) in the hip

238 Here, we show that sustained activation of extracellular signal-regulated kinases 1 and 2 (ERK1/2)

239 ses 1 and 2 (MNK1 and MNK2) are activated by extracellular signal-regulated kinases 1 and 2 (ERK1/2)

240 re, we show that sustained activation of the extracellular signal-regulated kinases 1 and 2 (ERK1/2)

241 c1 is associated with enhanced activities of extracellular signal-regulated kinases 1 and 2 (ERK1/2)

242 carcinoma (HCT116) cells treated with H2O2, extracellular signal-regulated kinases 1 and 2 (ERK1/2)

243 Abnormal regulation of extracellular signal-regulated kinases 1 and 2 has been

244 ated kinase 1 (MSK1), a downstream target of extracellular signal-regulated kinases 1 and 2, and an i

245 ion of p38 mitogen-activated protein kinase, extracellular signal-regulated kinases 1 and 2, and Jun

246 ethyl-D-aspartate receptors or activation of extracellular signal-regulated kinases 1 and 2, or block

247 nic ability, and invasiveness by suppressing extracellular signal-regulated kinases 1/2 (ERK1/2) and

248 treated with necrotic bone showed increased extracellular signal-regulated kinases 1/2 and Ikappa ki

249 TZ and lapatinib ability to block extracellular signal-regulated kinases 1/2 and phosphati

250 USP8 controls basal and acute stress-induced extracellular signal-regulated kinases 1/2 signaling in

251 Mechanistically, activation of extracellular signal-regulated kinases 1/2 were selectiv

252 Silencing FAK, but not extracellular signal-regulated kinases 1/2, abrogated th

253 ation of mammalian target of rapamycin, AKT, extracellular signal-regulated kinases 1/2, phosphatase

254 osphorylated focal adhesion kinase (FAK) and extracellular signal-regulated kinases 1/2, whereas Ln-3

255 receptor 2AT4 and induced phosphorylation of extracellular signal-regulated kinases and p38 mitogen-a

256 The extracellular signal-regulated kinases ERK1/2 represent

257 cells was associated with phosphorylation of extracellular signal-regulated kinases, implying externa

258 epithelial cells; elevates protein kinase A, extracellular signal-regulated kinases, SMAD and signal

259 f signal transduction cascades including the extracellular signal-regulated protein kinase (ERK), onc

260 lin genes, key transcription factor Myrf and extracellular signal-regulated protein kinase 1 and 2 (E

261 strongest response was detected for hepatic extracellular signal-regulated protein kinase 1 and 2 an

262 on of mitogen-activated protein kinase (MEK)-extracellular signal-regulated protein kinase 1/2 signal

263 Extracellular signal-regulated protein kinase 5 (ERK5) h

264 Here, we show that extracellular signal-regulated protein kinase 5 (Erk5) i

265 tivation of 4-HNE-induced phosphorylation of extracellular signal-regulated protein kinases (ERK1/2).

266 uired for agonist-induced phosphorylation of extracellular signal-regulated protein kinases 1 and 2 (

267 genetic knockout or knockdown caused ERK1/2 (extracellular signal-regulated protein kinases 1 and 2)

268 hrough phosphorylation of microglial ERK1/2 (extracellular signal-regulated protein kinases 1 and 2).

269 Inhibiting the canonical survival kinases extracellular signal-regulated protein kinases, protein

270 ng alpha-MSH production via CB1R-induced and extracellular-signal-regulated kinase 1/2 activation- an

271 ession by activating a pathway that involves extracellular-signal-regulated kinase, IL-6 and the tran

272 mouse model in which constitutive epidermal extracellular-signal-regulated kinase-MAP-kinase signall

273 Inhibitors of p38, extracellular-signal-regulated kinases 1/2 (p44/42 MAPK)

274 bitor reduced the phosphorylation of p38 and extracellular-signal-regulated kinases 1/2 (p44/42 MAPK)

275 cells with decreased phosphorylation of the extracellular-signal-regulated serine kinase ERK, which

276 region in the striatum, including the kinase extracellular-signal related kinase 1 (ERK1).

277 ith mammalian target of rapamycin (MTOR) and extracellular signal-related kinase (ERK) activation by

278 Extracellular signal-related kinase (ERK) is a key regul

279 Dysregulation of Ras-extracellular signal-related kinase (ERK) signaling give

280 se (MAPK) cascade, also known as the RAS-MEK-extracellular signal-related kinase (ERK1/2) pathway, ar

281 pression of mitogen-activated protein kinase/extracellular signal-related kinase (MAPK/ERK1/2) phosph

282 r claudin-1 knockdown, and protein levels of extracellular signal-related kinase 1/2 were reduced.

283 g depended on a signaling cascade leading to extracellular signal-related kinase activation.

284 Here we show that sustained extracellular signal-related kinase activity induced by

285 tiation treatment with the mitogen-activated extracellular signal-related kinase kinase inhibitor tra

286 as the GRIK2 and CLOCK genes, as well as the extracellular signal-related kinase pathway involved in

287 Here we use a minimal model of extracellular signal-related kinase regulation to explor

288 es display enhanced c-Jun N-terminal kinase, extracellular signal-related kinase, and p38 phosphoryla

289 d S100a9 messenger RNA expression through an extracellular signal-related kinase-dependent mechanism.

290 d cyst epithelial cell proliferation through extracellular signal-related kinase/MAPK inactivation.

291 suppressor of Ras (KSR), a scaffold for the extracellular signal-related kinase/mitogen-activated pr

292 ng relies on precise coordination of dynamic extracellular signals, signaling pathways, and cell shap

293 n state of satellite cells, but the specific extracellular signals that coordinate this regulation ar

294 However, the role of transporters in moving extracellular signals that regulate embryogenesis is lar

295 to the plasma membrane where they transduce extracellular signals to intracellular effectors.

296 intracellular adaptor protein that transmits extracellular signals to regulate malignant cell motilit

297 ated on the cell surface where they transmit extracellular signals to the cytoplasm.

298 between a cell and its environment, hosting extracellular signal transduction and nutrient transport

299 regulation to diverse natural and synthetic extracellular signals via GPCRs.

300 our results underscore fibulin-3 as a novel extracellular signal with strong activating effect on NF