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1 P response element-binding protein, p38, and extracellular signal-regulated kinase.
2 lation and subsequent phosphorylation of the extracellular signal-regulated kinase.
3 kinase interacting kinase-1, downstream from extracellular signal-regulated kinase.
4 frequent and spine density was increased via extracellular signal-regulated kinases.
6 s and sAC is required for the acute phase of extracellular signal regulated kinase 1/2 activation tri
7 cardiovascular disease, is known to activate extracellular signal regulated kinases 1 and 2 (ERK1/2).
10 , phosphoinositide 3-kinase (PI3K) p85alpha, extracellular signal-regulated kinase 1 (ERK1), or nucle
13 l as phosphatidylinositol 3-kinase (PI3K) or extracellular signal-regulated kinase 1 and 2 (Erk1/2) s
14 l as phosphatidylinositol 3-kinase (PI3K) or extracellular signal-regulated kinase 1 and 2 (Erk1/2) s
15 f G proteins, inhibition of cAMP production, extracellular signal-regulated kinase 1 and 2 phosphoryl
16 e to PDGF-BB, and reduced phosphorylation of extracellular signal-regulated kinase 1 and 2, Elk-1, p3
17 cell activation, as well as inflammasome and extracellular signal-regulated kinase 1 and 2-mediated n
18 ression and reduced levels of phosphorylated extracellular signal-regulated kinase 1 and active nucle
19 ted alpha2B-AR-mediated signaling, including extracellular signal-regulated kinase 1/2 (ERK1/2) activ
20 we previously discovered abnormally elevated extracellular signal-regulated kinase 1/2 (ERK1/2) activ
21 d transient IkappaBalpha phosphorylation and extracellular signal-regulated kinase 1/2 (ERK1/2) activ
22 that NPNT stimulates the phosphorylation of extracellular signal-regulated kinase 1/2 (ERK1/2) and p
24 ell proliferation and persistently activated extracellular signal-regulated kinase 1/2 (ERK1/2) durin
25 Recent work suggested that the activity of extracellular signal-regulated kinase 1/2 (ERK1/2) is in
26 protein kinase A-dependent activation of the extracellular signal-regulated kinase 1/2 (ERK1/2) pathw
27 g transcription factors or activation of the extracellular signal-regulated kinase 1/2 (Erk1/2) pathw
28 n target of rapamycin complex 1 (mTORC1) and extracellular signal-regulated kinase 1/2 (ERK1/2) pathw
29 s found to be dependent on activation of the extracellular signal-regulated kinase 1/2 (ERK1/2) signa
31 ogen-activated protein (MAP) kinases p38 and extracellular signal-regulated kinase 1/2 (ERK1/2), and
32 the eIF4E upstream kinase) or inhibitors of extracellular signal-regulated kinase 1/2 (ERK1/2), the
33 iptolide binds to and activates p38alpha and extracellular signal-regulated kinase 1/2 (ERK1/2), whic
34 asmin generation, but instead is mediated by extracellular signal-regulated kinase 1/2 (ERK1/2)-regul
35 only combined treatment of mitogen-activated extracellular signal-regulated kinase 1/2 (MEK1/2) and S
36 or inhibition of cAMP and phosphorylation of extracellular signal-regulated kinase 1/2 (pERK1/2), N-a
38 , we revealed that protein kinase A-mediated extracellular signal-regulated kinase 1/2 activation fun
39 C cells and resulted in potent inhibition of extracellular signal-regulated kinase 1/2 activation.
40 und that SMCs respond to Shh by upregulating extracellular signal-regulated kinase 1/2 and Akt phosph
41 -mediated signalling pathway, including p38, extracellular signal-regulated kinase 1/2 and c-Jun N-te
42 ulated PgLPS-mediated phosphorylation of the extracellular signal-regulated kinase 1/2 and c-Jun N-te
44 cKL + FGF23 increased the phosphorylation of extracellular signal-regulated kinase 1/2 and induced Fg
45 hosphates) in some signaling events, such as extracellular signal-regulated kinase 1/2 and label free
46 The stage- and time-specific activations of extracellular signal-regulated kinase 1/2 and protein ki
47 stromal-derived factor-1 (SDF1), through the extracellular signal-regulated kinase 1/2 pathway, invol
48 s down-regulated, followed by an increase in extracellular signal-regulated kinase 1/2 phosphorylatio
49 ells, Ptges expression was regulated through extracellular signal-regulated kinase 1/2 phosphorylatio
50 eased p38 mitogen-activated protein kinases, extracellular signal-regulated kinase 1/2 phosphorylatio
51 y neurons IL-31 triggered Ca(2+) release and extracellular signal-regulated kinase 1/2 phosphorylatio
52 Simultaneous inhibition of K-ras downstream extracellular signal-regulated kinase 1/2 signaling in p
53 inhibiting cAMP accumulation and activating extracellular signal-regulated kinase 1/2 signaling whil
54 f p-Src and mitogen-activated protein kinase-extracellular signal-regulated kinase 1/2 that were supp
55 ayed rapid increases in activated STAT1/3/5, extracellular signal-regulated kinase 1/2, AKT, CREB, an
56 es and were associated with an activation of extracellular signal-regulated kinase 1/2, and ribosomal
57 ory effects, increased inhibition of phospho-extracellular signal-regulated kinase 1/2, increased mit
58 ng MMP-9 secretion through the activation of extracellular signal-regulated kinase 1/2, p38, phosphoi
59 down resulted in decreased levels of phospho-extracellular signal-regulated kinase 1/2, phospho-c-Jun
60 ncluding retrovirus-associated DNA sequences/extracellular signal-regulated kinase 1/2, phosphoinosit
63 imarily an AMP-activated protein kinase- and extracellular signal-regulated kinase 1/2-dependent even
64 STAT3 was phosphorylated on serine 727 in an extracellular signal-regulated kinase 1/2-dependent mann
65 STAT3, which is significantly enhanced by an extracellular signal-regulated kinase 1/2-dependent mTOR
66 els of phosphorylated IkappaBalpha, Akt, and extracellular signal-regulated kinase 1/2; nuclear trans
67 F-1-induced cell migration and activation of extracellular signal-regulated kinases 1 and 2 (ERK) MAP
68 Here, we show that sustained activation of extracellular signal-regulated kinases 1 and 2 (ERK1/2)
69 ses 1 and 2 (MNK1 and MNK2) are activated by extracellular signal-regulated kinases 1 and 2 (ERK1/2)
70 re, we show that sustained activation of the extracellular signal-regulated kinases 1 and 2 (ERK1/2)
71 c1 is associated with enhanced activities of extracellular signal-regulated kinases 1 and 2 (ERK1/2)
73 response through activation of NF-kappaB via extracellular signal-regulated kinases 1 and 2 (ERK1/2)
74 uble tyrosine/threonine phosphorylation, the extracellular signal-regulated kinases 1 and 2 (ERK1/2)
75 carcinoma (HCT116) cells treated with H2O2, extracellular signal-regulated kinases 1 and 2 (ERK1/2)
76 kinase (JNK) but decreased levels of phospho-extracellular signal-regulated kinases 1 and 2 (ERK1/2).
78 ation with IL-13, IL-13Ralpha2 increased the extracellular signal-regulated kinases 1 and 2 phosphory
79 ated kinase 1 (MSK1), a downstream target of extracellular signal-regulated kinases 1 and 2, and an i
80 ion of p38 mitogen-activated protein kinase, extracellular signal-regulated kinases 1 and 2, and Jun
81 reased the phosphorylation (= activation) of extracellular signal-regulated kinases 1 and 2, c-Jun N-
82 ethyl-D-aspartate receptors or activation of extracellular signal-regulated kinases 1 and 2, or block
83 nic ability, and invasiveness by suppressing extracellular signal-regulated kinases 1/2 (ERK1/2) and
85 treated with necrotic bone showed increased extracellular signal-regulated kinases 1/2 and Ikappa ki
87 USP8 controls basal and acute stress-induced extracellular signal-regulated kinases 1/2 signaling in
90 ation of mammalian target of rapamycin, AKT, extracellular signal-regulated kinases 1/2, phosphatase
91 osphorylated focal adhesion kinase (FAK) and extracellular signal-regulated kinases 1/2, whereas Ln-3
93 2) (COT, MAP3K8) kinase activates the MEK1/2-extracellular-signal regulated kinase 1/2 MAP kinase sig
95 led to a decrease in phosphorylated Erk1/2 (extracellular-signal regulated kinases 1/2) in sprouting
96 AS silencing in amplified cell lines reduced extracellular-signal-regulated kinase 1/2 (ERK1/2) phosp
97 ng alpha-MSH production via CB1R-induced and extracellular-signal-regulated kinase 1/2 activation- an
99 bitor reduced the phosphorylation of p38 and extracellular-signal-regulated kinases 1/2 (p44/42 MAPK)
100 ory effects, a reduced inhibition of phospho-extracellular-signal-regulated kinases 1/2, a less sever
102 nt protein kinase II delta (CaMKIIdelta) and extracellular signal-regulated kinase 2 (ERK2) on the si
103 f miR-494 as a result of the inactivation of extracellular signal-regulated kinase 2 (ERK2), in turn
104 For the mitogen-activated protein kinase extracellular signal-regulated kinase 2 (Erk2), we obser
105 cents, phosphorylation of the trkB substrate extracellular signal-regulated kinase 42/44 (ERK42/44) i
107 thrombosis by increasing activation of MAPK extracellular signal-regulated kinase 5 (ERK5), a protei
109 that TRAF1 is required for solar UV-induced extracellular signal-regulated kinase-5 (ERK5) phosphory
110 ctivity in ICL, as this restored TCR-induced extracellular signal-regulated kinase activation and inc
111 tered phosphorylation of EGFR and downstream extracellular signal-regulated kinase activation in para
113 ortalin depletion induces transient MEK/ERK (extracellular signal-regulated kinase) activation and al
114 sympathetic nerves increase endothelial ERK (extracellular signal-regulated kinase) activity via adre
115 ) and lesser increases in phosphorylation of extracellular signal-regulated kinase and AK straining t
116 tyrosine phosphorylation and its downstream extracellular signal-regulated kinase and AKT phosphoryl
117 oncomitant down-regulation of phosphorylated extracellular signal-regulated kinase and myeloid cell l
118 orters, mRNAs, signaling (phosphorylation of extracellular signal-regulated kinase and phospholamban)
119 s inhibited modifications in the activity of extracellular signal-regulated kinase and zinc finger-co
120 receptor 2AT4 and induced phosphorylation of extracellular signal-regulated kinases and p38 mitogen-a
123 extracellular signal-regulated kinase kinase-extracellular signal-regulated kinase) and S6K-RPS6 (rib
124 -activated protein kinase, protein kinase B, extracellular signal-regulated kinase, and/or myosin lig
127 cal analysis of the MAP2K1 downstream target extracellular signal-regulated kinase demonstrated its p
128 1P receptor 3 (S1pr3) through Rho kinase and extracellular signal-regulated kinase-dependent pathway.
129 m after acute cocaine administration, via an extracellular-signal regulated kinase-dependent de novo
130 gonistic activity for Galphai activation and extracellular signal regulated kinase (ERK) 1/2 phosphor
131 cadherin potentiation of the FGFR stimulated extracellular signal regulated kinase (ERK) and protein
132 ed protein kinase C (PKC) in the cytosol and extracellular signal regulated kinase (ERK) in the cytos
133 ng MAPK inhibitors reveal that inhibition of extracellular signal regulated kinase (ERK) protects ETO
135 alized at 24 h, while the phosphorylation of extracellular signal regulated kinase (ERK) was increase
138 y involves the recruitment and activation of extracellular signal-regulated kinase (ERK) 1 and ERK2.
140 y upregulated, but uncoupled from downstream extracellular signal-regulated kinase (ERK) 1/2 signalin
141 ly localized D2R long isoform (D2LR) elicits extracellular signal-regulated kinase (ERK) activation a
143 d the dynamics of protein kinase C (PKC) and extracellular signal-regulated kinase (ERK) activation d
144 ositide 3-kinase (PI3Kgamma) plays a role in extracellular signal-regulated kinase (ERK) activation f
146 ctivation of S6K1 during extinction required extracellular signal-regulated kinase (ERK) activation i
147 uggested that this selection relies on basal extracellular signal-regulated kinase (Erk) activation m
148 ained intracellular calcium mobilisation and extracellular signal-regulated kinase (Erk) activation,
149 r of transcription (STAT) signaling, but not extracellular signal-regulated kinase (ERK) activation,
150 duced two mechanistically distinct phases of extracellular signal-regulated kinase (ERK) activation,
151 p4k4 silencing in ECs enhanced basal Ras and extracellular signal-regulated kinase (Erk) activities,
152 nstrate that matrix detachment downregulates extracellular signal-regulated kinase (ERK) activity and
154 lla (RVLM) elicits modest increases in local extracellular signal-regulated kinase (ERK) and blood pr
155 ) and E-prostanoid receptor (EP) 3, enhanced extracellular signal-regulated kinase (Erk) and c-fos ph
156 ltering the activity of the cellular kinases extracellular signal-regulated kinase (ERK) and glycogen
157 the mitogen-activated protein kinase (MAPK) extracellular signal-regulated kinase (ERK) and its upst
158 d the mitogen-activated protein kinase (MEK)/extracellular signal-regulated kinase (ERK) and mammalia
159 displayed modulated protein kinase C (PKC), extracellular signal-regulated kinase (ERK) and p38 mito
160 nd thereby inhibits the dephosphorylation of extracellular signal-regulated kinase (ERK) and p38 mito
161 well as downstream pathways including STAT5, extracellular signal-regulated kinase (Erk) and p38.
162 bition of PDE1 caused greater stimulation of extracellular signal-regulated kinase (ERK) and prolifer
164 rosarcoma cells naturally expressing mutated extracellular signal-regulated kinase (ERK) antigen, the
166 ifferentiation through its activation of the extracellular signal-regulated kinase (ERK) cascade.
167 ifferentiation through its activation of the extracellular signal-regulated kinase (ERK) cascade.
170 ired activation of nuclear factor kappaB and extracellular signal-regulated kinase (ERK) in monocytes
171 xogenous DA induced rapid phosphorylation of extracellular signal-regulated kinase (ERK) in naive hem
172 e protein, in addition to TrkA and activated extracellular signal-regulated kinase (ERK) in neurites,
173 ternalization of NK-1 and phosphorylation of extracellular signal-regulated kinase (ERK) in superfici
174 patial memory depends on rapid activation of extracellular signal-regulated kinase (ERK) in the dorsa
175 ese changes were reversed by soft matrix via extracellular signal-regulated kinase (ERK) inactivation
176 by combined treatment with rapamycin and an extracellular signal-regulated kinase (ERK) inhibitor.
179 eleasing hormone (GnRH) receptors (GnRHR) to extracellular signal-regulated kinase (ERK) or nuclear f
181 itogen-activated protein kinase kinase (MEK)-extracellular signal-regulated kinase (ERK) pathway in H
182 and migration of human keratinocytes through extracellular signal-regulated kinase (ERK) phosphorylat
183 CVID, like anergic B cells, have defects in extracellular signal-regulated kinase (ERK) phosphorylat
185 ellular signal-regulated kinase kinase (MEK)/extracellular signal-regulated kinase (ERK) scaffold, ki
187 ic activation is caused by the activation of extracellular signal-regulated kinase (ERK) signaling by
189 o the constitutive activation of the RAF-MEK-extracellular signal-regulated kinase (ERK) signaling pa
190 cells with an inactive versus an active RAS/extracellular signal-regulated kinase (ERK) signaling pa
192 tations in the genes involved in the RAF/MEK/extracellular signal-regulated kinase (ERK) signaling pa
193 uclear factor (NF) kappaB signaling, whereas extracellular signal-regulated kinase (ERK) signaling wa
195 ge interactions in driving cAMP, calcium, or extracellular signal-regulated kinase (ERK) signaling.
196 4 resistance to NB cells through upregulated extracellular signal-regulated kinase (ERK) signaling.
197 20 couples the BCR to PLCgamma2, Ca(2+), and extracellular signal-regulated kinase (Erk) signaling.
199 Here, we adapt the first-generation KTR for extracellular signal-regulated kinase (ERK) to allow eas
200 of NF-kappaB, c-Jun N-terminal kinase (JNK), extracellular signal-regulated kinase (ERK), and Akt (oc
201 e mitogen-activated protein kinases (MAPKs), extracellular signal-regulated kinase (ERK), c-JUN N-ter
203 ulin signaling/glucose homeostasis (ie, Akt, extracellular signal-regulated kinase (ERK), P70S6K), as
204 n of mitogen-activated protein kinase (MAPK)/extracellular signal-regulated kinase (ERK), PI3K/AKT, a
205 ream mitogen-activated protein kinase (MAPK)-extracellular signal-regulated kinase (ERK)-cFos pathway
206 enosine monophosphate (cAMP)-independent and extracellular signal-regulated kinase (ERK)-dependent pa
207 ampal-dependent memory by rapidly activating extracellular signal-regulated kinase (ERK)-dependent si
208 p56(Lck) and show that ShcA is important for extracellular signal-regulated kinase (ERK)-dependent up
209 ncodes multiple viral proteins that activate extracellular signal-regulated kinase (ERK)-mitogen-acti
213 , p21-activated protein kinases (PAK1/2) and extracellular signal-regulated kinase (ERK)/C-Jun N-term
214 n development and to differentially regulate extracellular signal-regulated kinase (ERK)/mitogen-acti
215 y inhibitors of the prolyl isomerase Pin1 or extracellular signal-regulated kinases (ERK) 1/2 or by p
216 imeric G proteins Gq and G12, as well as the extracellular signal-regulated kinases (ERK) 1/2 pathway
217 ecruitment, adenylyl cyclase inhibition, and extracellular signal-regulated kinases (ERK) activation.
218 helerythrine chloride suppressed the induced extracellular signal-regulated kinases (ERK) activity an
221 Transient activation of the highly conserved extracellular-signal-regulated kinase (ERK) establishes
222 the mitogen-activated protein (MAP) kinase (extracellular signal-regulated kinase [ERK]) signaling c
225 activated protein kinase kinase (MEK1/2) and extracellular signal-regulated kinase (ERK1/2) activatio
229 ession by activating a pathway that involves extracellular-signal-regulated kinase, IL-6 and the tran
230 cells was associated with phosphorylation of extracellular signal-regulated kinases, implying externa
231 nib and the mitogen-activated protein kinase/extracellular signal-regulated kinase inhibitor selumeti
232 al that the mitogen-activated protein kinase/extracellular signal-regulated kinase inhibitor trametin
233 ed BRAF and mitogen-activated protein kinase/extracellular signal-regulated kinase inhibitor treatmen
234 ,2 3-triene-3,11,22-trione], JSI-124, or the extracellular signal-regulated kinase inhibitor, 2-(2-am
238 bination of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase (MEK) and P
239 that the Ras/Raf/mitogen-activated protein, extracellular signal-regulated kinase kinase (MEK)/extra
240 d higher levels of mitogen-activated protein-extracellular signal-regulated kinase kinase 1, a molecu
241 ) induction by the mitogen-activated protein/extracellular signal-regulated kinase kinase inhibitor P
242 y niches counteracts combined BRAF/MEK (MAPK/extracellular signal-regulated kinase kinase) inhibitor
243 dependency on the mitogen-activated protein/extracellular signal-regulated kinase kinase-Erk1/2(MAPK
244 6 on both MEK-ERK (mitogen-activated protein/extracellular signal-regulated kinase kinase-extracellul
245 mouse model in which constitutive epidermal extracellular-signal-regulated kinase-MAP-kinase signall
247 thways like mitogen-activated protein kinase-extracellular signal-regulated kinase (MAPK-Erk) signali
248 kout, while mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/ERK) and non
249 ppaB kinase (IKK), mitogen-activated protein extracellular signal-regulated kinase (MEK), and Jun N-t
251 MP1 protein levels through activation of the extracellular signal-regulated kinase mitogen-activated
252 l with the induction of pserine727 Stat3 and extracellular signal-regulated kinase/mitogen-activated
253 FN-induced EMT depends on Src kinase and extracellular signal-regulated kinase/mitogen-activated
254 nutes), an essential memory molecule, via an extracellular-signal-regulated kinase/mitogen-activated
255 inal kinase (JNK) and c-Jun signals, but not extracellular signal-regulated kinase or Akt pathway act
256 -containing phosphatase [p-SHP2] and phospho-extracellular signal-regulated kinase [p-ERK]) is associ
257 levels for the phosphorylated forms of AKT, extracellular signal-regulated kinase, p38, STAT1, and S
258 zation demonstrated that this mutant induced extracellular signal-regulated kinase pathway activation
259 ors identified mutations predicted to induce extracellular signal-regulated kinase pathway activation
260 ls a new functional role for cocaine-induced extracellular signal-regulated kinase pathway independen
262 ), such as high expression of phosphorylated extracellular signal-regulated kinase (pERK) and reduced
263 ting these effects, levels of phosphorylated extracellular signal-regulated kinases (pERK) in the hip
264 of K-Ras effectors, including phosphorylated extracellular signal-regulated kinase, phosphorylated pr
265 Ho effects were observed for Ca(2+)o-induced extracellular signal-regulated kinase phosphorylation an
266 stress (S-SDS) induces D1 receptor-mediated extracellular signal-regulated kinase phosphorylation an
268 nally, endothelial nitric oxide synthase and extracellular signal-regulated kinase phosphorylation in
269 vemurafenib (480 mg/d) completely abrogated extracellular signal-regulated kinase phosphorylation of
270 the amygdala [CeA]) PACAP immunoreactivity, extracellular signal-regulated kinase phosphorylation, a
271 FSTL1 blocks Wnt7a-mediated repression of extracellular signal-regulated kinase phosphorylation, e
272 nsducer and activator of transcription 3 and extracellular signal-regulated kinase phosphorylation, w
273 were accompanied by inconsistent effects on extracellular signal-regulated kinase phosphorylation.
274 phosphate binding, calcium mobilization, and extracellular signal-regulated kinases phosphorylation a
275 s phospho-Ser10-histone H3 without modifying extracellular-signal regulated kinase phosphorylation in
276 However, the effect is not observed when extracellular-signal-regulated kinase phosphorylation is
277 endogenous inhibitor of calcineurin and Ras/extracellular signal-regulated kinase prohypertrophic si
278 reased phosphorylation level of both Src and extracellular signal regulated kinase proteins and with
279 manipulations were used to modulate the Ras-extracellular signal-regulated kinase (Ras-ERK) pathway,
280 rat sarcoma/mitogen-activated protein kinase/extracellular signal-regulated kinase (RAS/MEK/ERK), and
282 loss of DAB2IP results in the activation of extracellular signal-regulated kinase/RSK1 and phosphoin
283 hibition of mitogen-activated protein kinase/extracellular signal-regulated kinase signaling 6 hours
284 ndocytosis to block endosomal PACAP receptor extracellular signal-regulated kinase signaling attenuat
285 se/AKT, and mitogen-activated protein kinase/extracellular signal-regulated kinase signaling in mutat
287 EGFD-mitogen-activated protein kinase kinase-extracellular signal-regulated kinase signaling modulate
289 induced cPLA2 activation was mediated by the extracellular signal-regulated kinase signaling pathway.
295 B cells from tolerant recipients had reduced extracellular signal-regulated kinase signalling after B
296 eton by dephosphorylating eplin at two known extracellular signal-regulated kinase sites, serine 362
297 epithelial cells; elevates protein kinase A, extracellular signal-regulated kinases, SMAD and signal
298 directly upregulates FGF2 expression through extracellular signal-regulated kinase-Sp1 signaling.
299 atidylinositol 3-kinase-Akt, Ras-Raf-1, MEK1/extracellular signal-regulated kinase, sphingolipid, and
300 Mechanistically, reactive oxygen species and extracellular signal-regulated kinase were found to medi
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