ライフサイエンスコーパス: extragenic

1 erference effect occurred through a dominant extragenic agent.

2 All suppressor mutations are extragenic and map to either rpoB or rpoC, which encode

3 ative function, overexpressing sur-5 from an extragenic array partially suppresses the Multivulva phe

4 We identified one extragenic ced-4 suppressor, which has a mutation in the

5 pendent haploblocks of FGF1 and the adjacent extragenic chromosomal regions.

6 ever, gamma(1)34.5 deletion mutants, with an extragenic compensatory mutation, inhibit PKR activity b

7 Extragenic compensatory mutations, which partially suppr

8 msii contrasts with the upstream [corrected] extragenic crossover site for antigenic variation in Afr

9 The downstream extragenic crossover site in B. hermsii contrasts with t

10 nhancers may use mechanisms that differ from extragenic distal enhancers.

11 l into three classes: intragenic revertants, extragenic dominant suppressors (sup-39), and a single a

12 We isolated extragenic (E) FtsN*-suppressing mutations that restore

13 A and G insertions and sites of partial and extragenic editing in Physarum mitochondrial RNAs, as we

14 factors of myogenesis (MyoD and Myogenin) at extragenic enhancer regions coinciding with RNA synthesi

15 Both extragenic enhancers result in TS behavioral phenotypes

16 We showed previously that intronic and extragenic enhancers, when occupied by specific transcri

17 Environmental and extragenic factors are pivotal determinants of disease p

18 ingle expression site at rates determined by extragenic features of silent loci rather than similarit

19 We show that extragenic GATA switch sites occupied by GATA-2 associat

20 ranslation products from both intragenic and extragenic genomic regions, including peptides derived f

21 n of the SMF1 gene, which was isolated as an extragenic high-copy suppressor.

22 ssion vector pET23a(+) and examined if these extragenic I-1-Pases could complement the suhB mutation

23 side F3L, suggesting that the suppression is extragenic in nature.

24 The ability to inherit such extragenic information may provide adaptive benefits to

25 lopmental plasticity, genetic accommodation, extragenic inheritance and niche construction.

26 tations in the tRNA promoter elements, or in extragenic loci that inhibit RNA polymerase III complex

27 In contrast, at an extragenic locus lacking Pho4-binding sites, methylation

28 agenic single nucleotide polymorphism and an extragenic microsatellite marker are in linkage disequil

29 hanisms participating in pathogenesis and/or extragenic modification of phenotypic expression.

30 1, a genetic screen was employed to identify extragenic modifier mutations of a temperature-sensitive

31 e report here that mutations in gem-4 (gon-2 extragenic modifier) are capable of suppressing loss-of-

32 in-of-function mutations in the gem-1 (gon-2 extragenic modifier) locus.

33 rs (one enhancer and one suppressor) and two extragenic modifiers (both enhancers).

34 JSRD and provide a model system for studying extragenic modifiers in JSRD and other ciliopathies.

35 as well as mutations mapping to other genes (extragenic modifiers).

36 via an activation-tagging screen for bri1-5 extragenic modifiers.

37 aG-pspF intergenic region contains a complex extragenic mosaic element, RIB.

38 Furthermore, extragenic motile suppressors which arise in DeltafliX c

39 t viruses can be genetically separated by an extragenic mutation at another site in the viral chromos

40 le revertants possessed an identical, single extragenic mutation to create a partially constitutively

41 studies had undergone diverse intragenic and extragenic mutational events relative to flgS.

42 structure-function analysis of dNSF1 and the extragenic mutations identify gene products with related

43 sed a simple morphological screen to isolate extragenic mutations in six loci, designated ted (for re

44 Extragenic mutations in the acetyltransferase genes SAS2

45 tion of H2BK123 was recently challenged, and extragenic mutations in the strain background used for p

46 We show that dLeuR possesses one or more extragenic mutations that enhance ICP27 transcription, l

47 Extragenic mutations that enhance or suppress E2F activi

48 Two Arabidopsis thaliana extragenic mutations that suppress NaCl hypersensitivity

49 fic to phytochrome A (phyA), we screened for extragenic mutations that suppress the morphological phe

50 Three recessive extragenic mutations that suppress trm6-504 mutant pheno

51 We identified and characterized 14 extragenic mutations that suppressed the dominant egg-la

52 y on glycerol, but growth can be enhanced by extragenic mutations, termed glycerol suppressors, in th

53 can be dominantly enhanced and suppressed by extragenic mutations.

54 us-control regions, represent major sites of extragenic noncoding transcription.

55 zed revertants of shy1 null mutants carrying extragenic nuclear suppressor mutations.

56 AIMIE detected repeated extragenic palindrome (REP) elements, CRISPR repeats, up

57 eotide (nt) sequence containing a repetitive extragenic palindrome (REP) from the chloramphenicol ace

58 ed a 389-kb interchromosomal insertion at an extragenic palindrome site at Xq27.1 that completely cos

59 Finally, mutagenesis of the repetitive extragenic palindromic (REP) elements within the yqjH-yq

60 Isolates were fingerprinted using repetitive extragenic palindromic (REP) polymerase chain reaction a

61 using degenerate primers based on repetitive extragenic palindromic (REP) sequences (REP-PCR) were co

62 Repetitive extragenic palindromic (REP) sequences are highly struct

63 epending largely on the number of repetitive extragenic palindromic (REP) sequences present.

64 s, derived from the gram-negative repetitive extragenic palindromic element, were also applied to 18

65 Repetitive extragenic palindromic PCR (rep-PCR) is less time-consum

66 sis, colony size, colony texture, repetitive extragenic palindromic PCR (rep-PCR) pattern, and cellul

67 Repetitive extragenic palindromic PCR (REP-PCR) separated 167 isola

68 trains by growth characteristics, repetitive extragenic palindromic PCR fragment pattern, and some bi

69 terized (sequencing of bla genes, repetitive extragenic palindromic polymerase chain reaction, pulse-

70 ophoresis (PFGE), ribotyping, and repetitive extragenic palindromic sequence-based PCR (rep-PCR) were

71 the 16S ribosomal DNA (rDNA) and repetitive extragenic palindromic sequence-PCR (REP-PCR) to charact

72 Repetitive extragenic palindromic sequences (REPs) are a class of e

73 s are structurally similar to the repetitive extragenic palindromic sequences of Escherichia coli, al

74 Over 375 repetitive extragenic palindromic sequences unique to Pss B728a whe

75 sed-field gel electrophoresis and repetitive extragenic palindromic-PCR), multilocus sequence type (M

76 MS isolates were genotyped by repetitive extragenic palindromic-polymerase chain-reaction (rep-PC

77 Enterobacteriaceae were typed by repetitive extragenic, palindromic PCR and pulsed-field gel electro

78 ailable evidence suggests that the two short extragenic regions at the genomic termini, the 3' leader

79 and flanked by the 3' leader and 5' trailer extragenic regions of genomic RNA.

80 ced in pol II-coding sequences compared with extragenic regions or inactive loci.

81 e chromatin domain including both intra- and extragenic regions.

82 These results indicate that GATA-2-bound extragenic regulatory elements recruit Pol II, GATA-1 bi

83 One recessive, red light-specific extragenic revertant, designated red1, was isolated.

84 An extragenic second-site suppressor of the mutant DNA-bind

85 de evidence for germ line transmission of an extragenic sequence-specific silencing factor and implic

86 Extragenic sequences in genomes, such as microRNA and CR

87 palindromic sequences (REPs) are a class of extragenic sequences, which form nucleotide stem-loop st

88 Using HIS3 and lacZ as reporters, extragenic spontaneous recessive mutations that allowed

89 Previous studies have demonstrated extragenic suppression in the PBDs, but the phenotypes o

90 Extragenic suppressor analysis identified Zip1, a bZIP (

91 A high-copy extragenic suppressor gene, designated DBP4 (DEAD box pr

92 ave now cloned the sudD gene, another of the extragenic suppressor genes of the bimD6 mutation.

93 Extragenic suppressor mutants of the chemotaxis-impaired

94 Spontaneous extragenic suppressor mutants that arose in the triple m

95 that expresses CL04 resulted in selection of extragenic suppressor mutants that grew efficiently usin

96 other site in the viral chromosome; (ii) the extragenic suppressor mutation does not affect neuroviru

97 t to wild-type phenotypes suggesting that an extragenic suppressor mutation is able to overcome the l

98 Although this virus contains an extragenic suppressor mutation that confers enhanced gro

99 A spontaneous extragenic suppressor mutation that overcame the stage I

100 Extragenic suppressor mutations occur in several genes e

101 A novel genetic scheme allowed us to isolate extragenic suppressor mutations that restored mutant Omp

102 In addition, we have isolated four extragenic suppressor mutations that suppress the long-f

103 Two extragenic suppressor mutations were identified as mappi

104 re then used to identify both intragenic and extragenic suppressor mutations.

105 The sel-1 gene was identified as an extragenic suppressor of a lin-12 hypomorphic mutant.

106 RSS1 is the first reported high-copy extragenic suppressor of a mutant nucleoporin.

107 Sgd1p: One allele of sgd1 acts as a dominant extragenic suppressor of a mutation in a predicted RNA-b

108 receptor kinase (BRL1) was identified as an extragenic suppressor of a weak bri1 allele, bri1-5, in

109 ila lacking Suppressor of Fused (Su(fu)), an extragenic suppressor of fu, indicating that Su(fu) is n

110 An allele-specific extragenic suppressor of mglA8, named mas815 (mglA8 supp

111 Here we show that an extragenic suppressor of Raf, Su(Raf)1, encodes a Drosop

112 We previously cloned the sudA gene, an extragenic suppressor of the heat-sensitive bimD6 mutati

113 f RSS1 (Rat Seven Suppressor) as a high-copy extragenic suppressor of the rat7-1 temperature-sensitiv

114 In this study, we demonstrate that an extragenic suppressor of the temperature sensitivity of

115 rvation as a basis for genetic selection, an extragenic suppressor of Tus-mediated arrest of DNA repl

116 We carried out an extragenic suppressor screen in PA103DeltafimX bacteria

117 es a 5'-3' exonuclease, was identified as an extragenic suppressor that increases the half-life of rh

118 ear to form colonies only after acquiring an extragenic suppressor(s).

119 tic interaction, and are rescued by the same extragenic suppressor, Su(DTS)-1.

120 ions were alpha1-tubulin pseudorevertants or extragenic suppressors (the majority alter the beta1-tub

121 se essential cellular functions, we selected extragenic suppressors and identified rimJ as a high-cop

122 We identified nine extragenic suppressors as alleles of MAS2 (MORPHOLOGY OF

123 nce of an exogenous reductant and accumulate extragenic suppressors at a high frequency.

124 (iv) All extragenic suppressors contained an R229-->L mutation in

125 ure-sensitive mutations in the xcpT gene and extragenic suppressors for one of the mutants.

126 Two extragenic suppressors have been mapped to a groEL segme

127 uppressor decreased the general influx while extragenic suppressors increased the efflux of TolC-AcrA

128 Extragenic suppressors map to an unlinked gene, flhB, wh

129 Four of the mutants yielded extragenic suppressors mapping to the FlaII or FlaIIIB r

130 SUF13 and SUF14 genes were identified among extragenic suppressors of +1 frameshift mutations.

131 s within the motor, we attempted to identify extragenic suppressors of 31 dominant, plasmid-borne all

132 suppressor of divK) alleles were isolated as extragenic suppressors of a cold-sensitive divK mutation

133 A screen for extragenic suppressors of a cold-sensitive ydr1 (ydr1(cs

134 involved in thermotolerance, we screened for extragenic suppressors of a dominant-negative allele of

135 is consistent with genetic studies in which extragenic suppressors of a mutant TolC strain were foun

136 In a screen for extragenic suppressors of a silencing defective rap 1s h

137 exocyst degradation pathway, we screened for extragenic suppressors of a temperature-sensitive fissio

138 netic screen in Saccharomyces cerevisiae for extragenic suppressors of a temperature-sensitive npl4 a

139 We isolated spontaneous extragenic suppressors of a temperature-sensitive, letha

140 n vivo, we performed a genetic selection for extragenic suppressors of a yeast TBP mutant that exhibi

141 asmA mutations were isolated as extragenic suppressors of an OmpF assembly mutant, OmpF3

142 We have isolated seven cold-sensitive extragenic suppressors of bimD6 heat sensitivity that re

143 UPF2, UPF3, and ICK1, were represented among extragenic suppressors of ctf13-30.

144 Sequenced spontaneous extragenic suppressors of dksA polyauxotrophy are freque

145 f the switch-motor complex, we have isolated extragenic suppressors of dominant and partially dominan

146 A search for extragenic suppressors of gal4D identified recessive mut

147 Extragenic suppressors of hls1 were identified as mutati

148 ntify these factors, we isolated spontaneous extragenic suppressors of hsp82-deltaHSE1, an allele of

149 Extragenic suppressors of MMM1 deletion mutants partiall

150 The isolation of extragenic suppressors of one of these spt3 mutations ha

151 ied a selection procedure for intragenic and extragenic suppressors of orange-light-inverted mutants

152 kismet (kis) was identified in a screen for extragenic suppressors of Polycomb (Pc) and subsequently

153 Here we show that extragenic suppressors of the 3' stem mutation map to th

154 ed in these processes, we have isolated four extragenic suppressors of the A. nidulans nimX2(cdc2) te

155 unction with bimD, we conducted a screen for extragenic suppressors of the bimD5 and bimD6 mutations.

156 e, we performed a genetic screen to identify extragenic suppressors of the cold-sensitive growth defe

157 we describe the isolation of 12 spontaneous extragenic suppressors of the doa4-1 mutation; these inv

158 We performed a screen for extragenic suppressors of the nimA1 allele and isolated

159 otoprotection, we isolated and characterized extragenic suppressors of the npq1 lor1 double mutant of

160 entifying interacting proteins, a screen for extragenic suppressors of the temperature-sensitive nudC

161 Cloning of extragenic suppressors of the ts allele of YPT6 has reve

162 We isolated extragenic suppressors of the Y68A plaque formation defe

163 trichome branch initiation, we screened for extragenic suppressors of the zwi-3 mutation and isolate

164 In a genetic screen we have identified extragenic suppressors of this gain-of-function mutant.

165 Two extragenic suppressors of TolC(R367H), mapping in the re

166 mutation, we isolated a number of intra- and extragenic suppressors that increase in vivo GroE chaper

167 Delta(lapA lapB) mutant accumulated extragenic suppressors that mapped either to lpxC, waaC,

168 e TolC mutant (TolCP246R,S350C), we isolated extragenic suppressors that mapped within the acrRAB loc

169 Extragenic suppressors that regain the ability to synthe

170 otype in soft agar at 24 degrees C contained extragenic suppressors that were null mutations mapping

171 Ten recessive, extragenic suppressors were identified.

172 Multicopy extragenic suppressors were selected in strains carrying

173 Dosage and extragenic suppressors were selected.

174 Extragenic suppressors with restored capacity to replica

175 ly poor flagellation and swarming, generated extragenic suppressors, all of which mapped to flgB, one

176 ew bld2 alleles and three partially dominant extragenic suppressors, rgn1-1, rgn1-2, and rgn1-3.

177 revertants of priA2::kan strains that carry extragenic suppressors.

178 The remaining eex alleles were extragenic to pol2-4.

179 The prevalence of suppressors extragenic to the Pol epsilon gene suggests that factors

180 suggests a putative functional role for the extragenic transcription observed at the beta-globin and

181 gation eliminated the synthesis of genic and extragenic transcripts and eliminated Pol II from the be

182 A DNase I hypersensitive site and extragenic transcripts at IFNgCNS2 correlated positively