ライフサイエンスコーパス: extragonadal

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1 e patients with stage III and IV gonadal and extragonadal (all stages) MGCT were enrolled onto this P

2 rphic fashion, sex differences are caused by extragonadal and dosage effects of genes encoded on sex

3 d the responses of their spermatogenesis and extragonadal androgen actions (including gonadotropin su

4 ethod, that a specific T dose could maintain extragonadal androgen actions without simultaneously act

5 enesis, while simultaneously maintaining the extragonadal androgen actions, such as potency and libid

6 Biosynthesis of extragonadal androgen may contribute to the progression

7 stration-resistant prostate cancers (CRPCs), extragonadal androgen sources may sustain tumor growth d

8 There were five extragonadal cases and two patients with late relapse (r

9 ersist in castrated rabbits, suggesting that extragonadal factors contribute to the differences in ve

10 varian or testicular function, while leaving extragonadal function intact.

11 entry criteria included relapsed gonadal and extragonadal germ cell cancer unlikely to be cured by st

12 The extragonadal germ cell tumors (EGCTs) represent a unique

13 Extragonadal germ cell tumors of infancy, one of the mos

14 iectomized WT than in ArKO, emphasizing that extragonadal local estradiol plays a critical role in fe

15 ration of primordial germ cells (PGCs) in an extragonadal location, followed by directed migration to

16 ed ovarian (n = 44), testicular (n = 7), and extragonadal (n = 22).

17 ctomy and before chemotherapy for those with extragonadal nonseminomas.

18 survival is not seen in those patients with extragonadal nonseminomatous germ cell tumors.

19 stage II-IV testicular, II-III ovarian, I-II extragonadal, or stage I gonadal tumors with subsequent

20 In contrast, for patients with an extragonadal primary tumor or with a testis primary tumo

21 ave a better prognosis than patients with an extragonadal primary tumor site or an IR to first-line t

22 Four of six patients with extragonadal primary tumors and two of four who failed t

23 Cases of gonadal and extragonadal primary were included in the nationwide coh

24 Two of three extragonadal seminomas are continuously disease-free.

25 ic germ cell tumors (GCTs) commonly arise at extragonadal sites.

26 In considering the possibility of an extragonadal source of germ cells, we show expression of

27 These residual extragonadal sources of androgens allow prostate cancer

28 he gonad, the FSHR has also been reported in extragonadal tissues including bone, placenta, endometri

29 confined to gonads and at low levels to some extragonadal tissues like human umbilical vein endotheli

30 in both male and female mammals in multiple extragonadal tissues.

31 None of the 32 patients with nonseminomatous extragonadal tumors are disease-free compared with 30 of

32 s age > 11 years with either stage III to IV extragonadal tumors or stage IV ovarian tumors with pred

33 n (n = 74) tumors and 165 with stage I to IV extragonadal tumors were enrolled.

34 % for patients with ovarian, testicular, and extragonadal tumors, respectively.

35 ts, including adolescents, and patients with extragonadal tumours, high tumour markers at diagnosis,

36 g in infancy and early childhood are usually extragonadal, whereas older children predominantly prese

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