ライフサイエンスコーパス: extramedullary hematopoiesis

1 and a pathological reduction in red pulp and extramedullary hematopoiesis.

2 showed transient bone marrow depression and extramedullary hematopoiesis.

3 enitor cells in the bone marrow, and splenic extramedullary hematopoiesis.

4 R/Hedgehog-related genes in spleen, reducing extramedullary hematopoiesis.

5 rythroid differentiation and greatly reduced extramedullary hematopoiesis.

6 a dramatic increase in HSPC mobilization and extramedullary hematopoiesis.

7 a, they have macrocytic anemia and increased extramedullary hematopoiesis.

8 chitecture, bone marrow hypocellularity, and extramedullary hematopoiesis.

9 d splenomegaly with altered architecture and extramedullary hematopoiesis.

10 cture, and infected mice exhibited extensive extramedullary hematopoiesis.

11 at was accompanied by splenomegaly caused by extramedullary hematopoiesis.

12 mph nodes were enlarged and exhibited marked extramedullary hematopoiesis.

13 fibrosis, osteosclerosis, angiogenesis, and extramedullary hematopoiesis.

14 with a recovery of medullary and decrease in extramedullary hematopoiesis.

15 ive hematopoiesis, bone marrow fibrosis, and extramedullary hematopoiesis.

16 nto RBCs via formation of blood islands with extramedullary hematopoiesis.

17 Cs in the spleen, where we observed enhanced extramedullary hematopoiesis.

18 tes, varying degrees of marrow fibrosis, and extramedullary hematopoiesis.

19 defect correlated with disease duration and extramedullary hematopoiesis.

20 rial infection, resulting in a transition to extramedullary hematopoiesis.

21 ls for growing in LEC-1 domains during liver extramedullary hematopoiesis.

22 hetic nervous system, expanded medullary and extramedullary hematopoiesis.

23 e blood cells, bone marrow hypercellularity, extramedullary hematopoiesis, a tendency for thrombosis,

24 , an increase in splenic megakaryocytes, and extramedullary hematopoiesis accompany the hematologic c

25 e capacity is sustained by expanded sites of extramedullary hematopoiesis and is accompanied by multi

26 Mechanistically, FTY720 enhanced extramedullary hematopoiesis and massive accumulation of

27 thalassemia, with the potential of reversing extramedullary hematopoiesis and preventing splenectomy.

28 K hyperplasia, myelofibrosis, and consequent extramedullary hematopoiesis and splenomegaly.

29 2 heterozygous mutant mice exhibit increased extramedullary hematopoiesis and susceptibility to lymph

30 f Hmga2 enhanced megakaryopoiesis, increased extramedullary hematopoiesis, and accelerated the develo

31 enlargement of the spleen, increased splenic extramedullary hematopoiesis, and altered clinicopatholo

32 mune manifestations, including splenomegaly, extramedullary hematopoiesis, and autoantibody productio

33 loproliferation, ineffective erythropoiesis, extramedullary hematopoiesis, and bone marrow fibrosis a

34 acterized by erythrocytosis, granulocytosis, extramedullary hematopoiesis, and bone marrow fibrosis,

35 1(+) granulocytes, splenomegaly, evidence of extramedullary hematopoiesis, and bone marrow fibrosis,

36 enlarged spleen due to lymphoid hyperplasia, extramedullary hematopoiesis, and bone marrow hypoplasia

37 atopoietic stem and progenitor cell cycling, extramedullary hematopoiesis, and differentiation defect

38 gh incidence of premature death, age-related extramedullary hematopoiesis, and lack of early degenera

39 ymph nodes, splenomegaly due to erythrocytic extramedullary hematopoiesis, and lymphoid hyperplasia w

40 ave important implications for understanding extramedullary hematopoiesis, and may be relevant to cur

41 icrovesicular fatty metamorphosis, prolonged extramedullary hematopoiesis, and portal hypercellularit

42 poietic defects develop without compensatory extramedullary hematopoiesis, and the loss of HSCs occur

43 osis, resulting in extreme levels of splenic extramedullary hematopoiesis, anemia, and leukopenia.

44 Dysmegakaryopoiesis and extramedullary hematopoiesis characterize primary myelof

45 gic malignancy characterized by BM fibrosis, extramedullary hematopoiesis, circulating CD34+ cells, s

46 rease in myeloid progenitor populations, and extramedullary hematopoiesis composed of maturing myeloi

47 e develop severe neutrophilia, splenomegaly, extramedullary hematopoiesis, decreased body weight, and

48 ient mice have a peripheral leukocytosis and extramedullary hematopoiesis, demonstrating that Lsc is

49 der steady-state conditions and mobilize for extramedullary hematopoiesis during periods of stress su

50 characterized by splenomegaly, leukocytosis, extramedullary hematopoiesis (EMH) in spleen and liver w

51 Extramedullary hematopoiesis (EMH) is induced during pre

52 Extramedullary hematopoiesis (EMH) refers to the differe

53 Ineffective erythropoiesis and extramedullary hematopoiesis (EMH) regress, as reflected

54 ere anemia (2-4 g/dL), massive splenomegaly, extramedullary hematopoiesis (EMH), and hepatic iron ove

55 aly, fibrotic and hypercellular bone marrow, extramedullary hematopoiesis in both spleen and liver, a

56 possibility of hemolytic anemia and splenic extramedullary hematopoiesis in Nrf2(-/-) mice.

57 We found that G6 significantly reduced extramedullary hematopoiesis in the liver and splenomega

58 mplicate IL-25-elicited MPP(type2) cells and extramedullary hematopoiesis in the promotion of Th2 cyt

59 Moreover, AEP deficiency provokes extramedullary hematopoiesis in the spleen and abnormall

60 erative phenotype, which was associated with extramedullary hematopoiesis in the spleen and liver, wa

61 lls; myeloid hyperplasia in bone marrow; and extramedullary hematopoiesis in the spleen and liver.

62 y high white blood cell counts and extensive extramedullary hematopoiesis in the spleen, liver, bone

63 tipotential progenitor cell mobilization and extramedullary hematopoiesis in the spleen.

64 one mass, reduced medullary cavity space and extramedullary hematopoiesis in the spleen.

65 marrow, and spleen; significantly increased extramedullary hematopoiesis in the spleen; and a 2-fold

66 sease phenotype-bone marrow stromal changes, extramedullary hematopoiesis, ineffective erythropoiesis

67 d circulating MIP-1alpha and ameliorated the extramedullary hematopoiesis, inflammation, and osteopen

68 Splenic extramedullary hematopoiesis is an integral component of

69 tipotential progenitor cell mobilization and extramedullary hematopoiesis, leading to decreased produ

70 oplasms (MPNs), including varying degrees of extramedullary hematopoiesis (myeloid metaplasia) and sp

71 In the orthotopic BALB/cJ model, extramedullary hematopoiesis occurred in the spleen, res

72 However, KRAS activation enhanced extramedullary hematopoiesis of MA4-expressing cell line

73 it, leukocytosis, megakaryocyte hyperplasia, extramedullary hematopoiesis resulting in splenomegaly,

74 , lead to autoinflammatory disease involving extramedullary hematopoiesis, skin and bone lesions.

75 by bone marrow fibrosis, myeloproliferation, extramedullary hematopoiesis, splenomegaly and leukemic

76 opoietic stem cell function, contributing to extramedullary hematopoiesis, splenomegaly, BM failure,

77 Extramedullary hematopoiesis was also evident, and granu

78 Increased extramedullary hematopoiesis was associated with elevate

79 ecrease in bone marrow hematopoiesis, active extramedullary hematopoiesis was observed in the spleen

80 Marked splenomegaly caused by extramedullary hematopoiesis was observed.

81 n the P-loop of Gimap5, lymphopenia, hepatic extramedullary hematopoiesis, weight loss, and intestina

82 Greater HSPC mobilization and extramedullary hematopoiesis were reversed by raising HD

83 -old IRP1(-/-) mice exhibit splenomegaly and extramedullary hematopoiesis, which is corrected in olde

84 Instead, these animals exhibit extensive extramedullary hematopoiesis with progressive splenomega