ライフサイエンスコーパス: extrapulmonary

1 ight atrium versus 12 in the left atrium; 15 extrapulmonary).

2 and 3071 (9.6%) were combined pulmonary and extrapulmonary.

3 losis complex; 29 were pulmonary, and 8 were extrapulmonary.

4 Comorbid conditions can be pulmonary or extrapulmonary.

5 eolar collapse were similar in pulmonary and extrapulmonary acute lung injury groups.

6 ary acute lung injury) or intraperitoneally (extrapulmonary acute lung injury).

7 oneally (20 mg/kg in 0.5 mL of saline/mouse, extrapulmonary acute lung injury).

8 In extrapulmonary acute lung injury, CPAP-30 and STEP-30/30

9 Compared with extrapulmonary acute lung injury, mesenchymal stem cell

10 and STEP-30/30 yielded endothelial injury in extrapulmonary acute lung injury.

11 l, and remodeling properties in pulmonary or extrapulmonary acute lung injury.

12 respiratory distress syndrome compared with extrapulmonary acute respiratory distress syndrome but p

13 led ventilation and variable ventilation; in extrapulmonary acute respiratory distress syndrome, howe

14 ress syndrome, n = 12) or intraperitoneally (extrapulmonary acute respiratory distress syndrome, n =

15 In extrapulmonary acute respiratory distress syndrome, only

16 preserved E-cadherin in lung tissue only in extrapulmonary acute respiratory distress syndrome, thus

17 te respiratory distress syndrome, but not in extrapulmonary acute respiratory distress syndrome, vari

18 al ventilation in experimental pulmonary and extrapulmonary acute respiratory distress syndrome.

19 nary acute respiratory distress syndrome and extrapulmonary acute respiratory distress syndrome.

20 ry distress syndrome donors on pulmonary and extrapulmonary acute respiratory distress syndrome.

21 ity is regulated by subsets of pulmonary and extrapulmonary afferent nerve fibers, which continuously

22 nglion neurones project C-fibres to both the extrapulmonary airways (larynx, trachea and bronchus) an

23 COPD is a heterogeneous disease with both extrapulmonary and pulmonary components.

24 Intrapatient diversity was found both at the extrapulmonary and respiratory sites, meaning that this

25 k in nonambulatory patients or in those with extrapulmonary and smear-negative tuberculosis.

26 ely pulmonary, 5085 (15.9%) were exclusively extrapulmonary, and 3071 (9.6%) were combined pulmonary

27 aminophen diminished NPSH in nasal, thoracic extrapulmonary, and lung tissues; it also induced the ox

28 4.2]) or disease that was both pulmonary and extrapulmonary (aPR, 2.4 [95% CI, 2.1-2.9]) were associa

29 ed bacterial burdens in the lungs, increased extrapulmonary bacterial dissemination, and more severe

30 samples collected post mortem from lung and extrapulmonary biopsies of 44 subjects in KwaZulu-Natal,

31 lone on day 3 in patients with infectious or extrapulmonary causes of acute respiratory distress synd

32 1) but not in patients with noninfectious or extrapulmonary causes of acute respiratory distress synd

33 ess syndrome but only at day 3 in those with extrapulmonary causes of acute respiratory distress synd

34 tcome was a composite of major pulmonary and extrapulmonary complications occurring within the first

35 h chronic conditions, such as arthritis, and extrapulmonary complications, such as encephalitis.

36 administered, to a variety of pulmonary and extrapulmonary complications.

37 onary control) or intraperitoneally (0.5 mL, extrapulmonary control).

38 arcoma, esophageal candidiasis, CMV disease, extrapulmonary cryptococcosis, toxoplasmic encephalitis,

39 of tuberculosis cases that were exclusively extrapulmonary differed by lineage: East Asian, 13.0%; E

40 Forty of the patients had extrapulmonary disease (17 had disseminated disease, 11

41 us infection (aPR, 1.43; 95% CI, 1.15-1.77), extrapulmonary disease (aPR, 3.02; 95% CI, 2.60-3.52), a

42 Exclusively extrapulmonary disease (aPR, 3.7 [95% CI, 3.3-4.2]) or d

43 retroviral therapy), as well as treatment of extrapulmonary disease (central nervous system, pericard

44 roportionably affected by smear-negative and extrapulmonary disease and who are also most adversely a

45 ibraries with pooled sera from patients with extrapulmonary disease and with sera from patients with

46 nchioloalveolar carcinoma and no evidence of extrapulmonary disease received transplants of either on

47 Subacute, hematogenous, and extrapulmonary disease tends to be more frequent in infa

48 ive human immunodeficiency virus status, and extrapulmonary disease were also significantly associate

49 pulmonary and constitutional symptoms, more extrapulmonary disease, and fewer cavitary lesions on ch

50 e to induce pathological lesions or to cause extrapulmonary disease, despite retaining its ability to

51 ectrum of dissemination was noted, including extrapulmonary disease.

52 001 and 30 May 2006, including 59 (45%) with extrapulmonary disease.

53 vis, which was independently associated with extrapulmonary disease.

54 developed pulmonary TB, either alone or with extrapulmonary disease.

55 l infection, the organization of granulomas, extrapulmonary dissemination and vaccine-induced protect

56 Extrapulmonary dissemination appeared to be a function o

57 Extrapulmonary dissemination can lead to infection of th

58 CatB was dispensable for lung infection and extrapulmonary dissemination in vivo.

59 It has been implicated in extrapulmonary dissemination of M. tuberculosis from the

60 Extrapulmonary dissemination of mycoplasmas with coloniz

61 ntrapulmonary L. pneumophila infections with extrapulmonary dissemination of the bacteria to the sple

62 Extrapulmonary dissemination resulted in acquisition of

63 Extrapulmonary dissemination was almost exclusively note

64 . pneumoniae was inhibited by lovastatin and extrapulmonary dissemination was enhanced, both reversib

65 imals showed reduced pulmonary pathology and extrapulmonary dissemination, and protection correlated

66 f progression to disease, various extents of extrapulmonary dissemination, and various degrees of cav

67 While not preventing extrapulmonary dissemination, the coadministered T cells

68 nimal model to study cavity pathogenesis and extrapulmonary dissemination.

69 ction can result in eradication, latency, or extrapulmonary dissemination.

70 nterfere with cryptococcal neurotropism upon extrapulmonary dissemination.

71 that the most likely candidate transducer of extrapulmonary effects of iNO was nitrite.

72 ncreasing epidemiological evidence points to extrapulmonary effects, including positive associations

73 the dissemination of P. carinii organisms in extrapulmonary (EP) tissues.

74 jects with latent (LTBI), pulmonary (PTB) or extrapulmonary (EPTB) tuberculosis remains unclear.

75 Elevated extrapulmonary extracellular matrix turnover was associa

76 Finally, a variety of extrapulmonary factors may impact upon airway disease, i

77 (QS/QT), assessing the impact of intra- and extrapulmonary factors on the relationship and thus the

78 airways and surrounding lung parenchyma, and extrapulmonary factors.

79 lymph nodes represent reactive adenitis, and extrapulmonary forms of tuberculosis (including lymphati

80 hus imparts opposing effects upon intra- and extrapulmonary host defense by inducing tissue-divergent

81 is serum to infected C3H-SCID mice prevented extrapulmonary infection and disease, while the severity

82 Concern over early postoperative extrapulmonary infection may suggest a benefit of initia

83 ho develop chronic coccidioidal pneumonia or extrapulmonary infection often have complicated courses

84 r HIV status, cases were more likely to have extrapulmonary involvement (47.6% versus 11.6%, p = 0.05

85 vs 144 microL), and were more likely to have extrapulmonary involvement (75% vs 18%, p=0.03) and conc

86 correlated with severity of lung disease or extrapulmonary involvement and was found in one patient

87 Overall, extrapulmonary involvement was a risk factor for shorter

88 ng transplantation (LT) due to concerns that extrapulmonary involvement will yield worse outcomes.

89 Extrapulmonary loci of virus replication seem possible.

90 tract even after a nasal challenge, whereas extrapulmonary lymphoid responses enhanced responses in

91 te-like ability of CD4(+) T cells to contain extrapulmonary M. tuberculosis dissemination at very ear

92 eted macaques surprisingly led to very early extrapulmonary M. tuberculosis dissemination, whereas CD

93 he electronic charts of 149 patients with an extrapulmonary malignant neoplasm and a solitary pulmona

94 Most patients (92%) had extrapulmonary manifestations, including shock, acute ki

95 symptoms, comorbid conditions, pulmonary and extrapulmonary manifestations, measures of severity of i

96 athologies, including asthma, and a range of extrapulmonary manifestations.

97 age lung disease due to SSc who have limited extrapulmonary manifestations.

98 No evidence of extrapulmonary MERS-CoV antigens were detected, includin

99 o intervene in a wide range of pulmonary and extrapulmonary metastatic disease.

100 NA), respectively, in pulmonary (n = 18) and extrapulmonary (n = 4) lesions from 22 women with LAM (1

101 nds on the histologic characteristics of the extrapulmonary neoplasm and the patient's smoking histor

102 the nodule were correlated with those of the extrapulmonary neoplasm and with patient age and smoking

103 ults with otherwise unexplained disseminated/extrapulmonary Nocardia infections, anti-GM-CSF autoanti

104 Plasma from patients with disseminated/extrapulmonary nocardiosis and healthy controls was scre

105 ted with mediastinal adenopathy or suspected extrapulmonary nonnodal metastases (P <.05).

106 veral important sequelae (both pulmonary and extrapulmonary) occur in these adult patients including

107 poxemic respiratory failure and considerable extrapulmonary organ dysfunction and is associated with

108 tionship between fibrogenesis, pulmonary and extrapulmonary organ dysfunction, and outcome during the

109 Lower tidal volumes (Vts) attenuate extrapulmonary organ injury in other disease states and

110 ycobacterial responses in both pulmonary and extrapulmonary organ systems of mice, which may be impor

111 creased mycobacterial loads in pulmonary and extrapulmonary organ systems.

112 y improve lung function but could jeopardize extrapulmonary-organ perfusion.

113 rculosis infection burdens in lung lobes and extrapulmonary organs than did the control groups receiv

114 he respiratory tract, virus dissemination to extrapulmonary organs, lymphopenia, significantly elevat

115 also isolated from the brains, but not other extrapulmonary organs, of infected animals.

116 ith the ability of VN/1203 to disseminate to extrapulmonary organs.

117 induce damage to 28S rRNA in kidney or other extrapulmonary organs.

118 lity to control M. tuberculosis infection in extrapulmonary organs.

119 s is assumed to be intrapulmonary, but their extrapulmonary origin and especially derivation from bon

120 spiratory disorders, and are associated with extrapulmonary pathologies.

121 a range of airway inflammation and lung and extrapulmonary pathologies.

122 survival interval, more severe pulmonary and extrapulmonary pathology, and a higher bacterial burden

123 nonspecific immune response and the rate of extrapulmonary phagocytosis.

124 Spoligotyping of 54 pulmonary and extrapulmonary positive tissues from 30 subjects showed

125 nd normal lungs to predicted full inflation (extrapulmonary restriction); or (2) increased capillary

126 onary vein isolation plus linear ablation of extrapulmonary rotor domains.

127 ges, and it can also result in other serious extrapulmonary sequelae.

128 Patients with extrapulmonary shunting, clear chest radiographs, and ad

129 elease platelets in the lungs originate from extrapulmonary sites such as the bone marrow; we observe

130 by Pneumocystis in the lung and possibly at extrapulmonary sites via circulating fungal components.

131 dicated that dissemination from the lungs to extrapulmonary sites was as frequent as between lung sit

132 ine-treated animals, and tumor recurrence in extrapulmonary sites was seen only in the cyclosporine-t

133 nd 10%-15% of cases of reactivation occur at extrapulmonary sites without active pulmonary tuberculos

134 asmal colonization of spleens and lesions in extrapulmonary sites, particularly spleens, hearts, and

135 d correlates with the spread of the virus to extrapulmonary sites.

136 le defect of 2E-TU-4 was in dissemination to extrapulmonary sites.

137 c Ag-specific immunity or chemoattraction at extrapulmonary sites.

138 reducing the number of yeast in the lung or extrapulmonary sites.

139 ective T cell immunity in both the lungs and extrapulmonary sites.

140 small cell lung cancer (SCLC) cell lines, 3 extrapulmonary small cell cancer (ExPuSC) cell lines, an

141 ung cancers, NSCLC, four mesotheliomas, five extrapulmonary small cell cancers) were analysed for PTE

142 in one patient each with platinum-resistant extrapulmonary small-cell and fluoropyrimidine- and irin

143 e human lung might be similarly derived from extrapulmonary sources, we examined lung specimens from

144 eater proportion of pulmonary specimens than extrapulmonary specimens (IPC C(T) > 34: 6% (47/731) ver

145 h C(T) values in pulmonary specimens but not extrapulmonary specimens (Spearman's coefficient 0.5043

146 Pulmonary specimens had greater load than extrapulmonary specimens [TTPs (interquartile range) of

147 n Southeast Asia and collected pulmonary and extrapulmonary specimens to evaluate the prevalence of m

148 3% of the pulmonary specimens and 50% of the extrapulmonary specimens were smear positive.

149 specimens was 60% for pulmonary and 75% for extrapulmonary specimens, while the IS6110 LDT sensitivi

150 sis isolates in smear-positive pulmonary and extrapulmonary specimens, while the sensitivity of the d

151 nts, including 89 pulmonary specimens and 23 extrapulmonary specimens.

152 MTB/RIF C(T) is a poor surrogate of load in extrapulmonary specimens.

153 ary specimens but an increased likelihood in extrapulmonary specimens.

154 Viremia and extrapulmonary spread of SARS CoV to liver and spleen, w

155 Extrapulmonary spread was not observed in either mice or

156 s a wide range of airway diseases as well as extrapulmonary symptoms.

157 Carefully selected patients without extrapulmonary systemic disease experience similar survi

158 lture-positive pulmonary TB (PTB; 91.3%) and extrapulmonary TB (EPTB; 92.3%), and the sensitivities o

159 + cell counts and decreased the incidence of extrapulmonary TB and genital ulcers in HIV-negative pat

160 ng seasonality in clustered TB and clustered extrapulmonary TB cases but not in clustered pulmonary T

161 ealed barely significant seasonality only in extrapulmonary TB cases.

162 sion was increased 2.3-fold in patients with extrapulmonary TB compared with patients with purely pul

163 agnosis of tuberculosis (TB) in children and extrapulmonary TB in adults continues to be a challenge.

164 y, diagnosis of smear-negative pulmonary and extrapulmonary TB remains challenging in such settings.

165 ation of MODS into diagnostic algorithms for extrapulmonary TB.

166 study supports the clinical use of iNO as an extrapulmonary therapeutic to improve organ function fol

167 ced growth characteristics in eggs, extended extrapulmonary tissue tropism, and pathogenicity in mice

168 ture of the host response to Coccidioides in extrapulmonary tissue.

169 ontrast, G-CSF mRNA was not increased in the extrapulmonary tissues examined (liver, spleen, and kidn

170 in cigarette smoke mediates CFTR defects in extrapulmonary tissues in smokers.

171 servations in humans support the notion that extrapulmonary tissues may be infected hematogenously by

172 th higher bacterial burdens in pulmonary and extrapulmonary tissues, development of more extensive hi

173 y involve the persistence of latent virus in extrapulmonary tissues, similar to what has been recentl

174 colysis) also underlies the abnormalities in extrapulmonary tissues, suggesting a global metabolic di

175 h increased cytokine and chemokine levels in extrapulmonary tissues.

176 oncentrations (80 ppm) inhibits IR injury in extrapulmonary tissues.

177 amount of the radioactivity was detected in extrapulmonary tissues.

178 crease in the fungal burden in pulmonary and extrapulmonary tissues.

179 to the systemic circulation, suggesting that extrapulmonary toxicity may be caused indirectly by lung

180 ited States, the proportion of patients with extrapulmonary tuberculosis (EPTB) has increased relativ

181 I, 1.79-341.1]; P = .02) and the presence of extrapulmonary tuberculosis (OR, 37.8 [95% CI, 2.78-513.

182 erculosis and pulmonary embolism, or between extrapulmonary tuberculosis and deep vein thrombosis.

183 were found significantly more likely to have extrapulmonary tuberculosis and negative tuberculin skin

184 is approach may be a useful method to detect extrapulmonary tuberculosis and the risk of death in imm

185 strain, it was isolated from a patient with extrapulmonary tuberculosis and vaccination with a subun

186 losis infection, pulmonary tuberculosis, and extrapulmonary tuberculosis are provided.

187 boy in North Dakota who was screened because extrapulmonary tuberculosis had been diagnosed in his fe

188 ew smear-negative samples from patients with extrapulmonary tuberculosis in our study, additional sim

189 East Asian lineage, the odds of exclusively extrapulmonary tuberculosis relative to exclusively pulm

190 ., San Diego, Calif.) for rapid diagnosis of extrapulmonary tuberculosis was evaluated by testing 178

191 The risk of extrapulmonary tuberculosis was higher among HIV-infecte

192 ren had pulmonary tuberculosis, 24 (41%) had extrapulmonary tuberculosis with or without pulmonary in

193 irs that can reactivate infection, producing extrapulmonary tuberculosis without lung involvement.

194 orld Health Organization stage 4 (other than extrapulmonary tuberculosis) and after 2 months of tuber

195 infection (eg, pulmonary tuberculosis versus extrapulmonary tuberculosis).

196 erculosis is one of the most common forms of extrapulmonary tuberculosis, it is a disease entity that

197 l tuberculosis, smear-negative tuberculosis, extrapulmonary tuberculosis, multidrug-resistant tubercu

198 the endpoint review committee), pulmonary or extrapulmonary tuberculosis, or any bacterial infectious

199 In extrapulmonary tuberculosis, the most common site of inf

200 mphadenitis (TBL) is the most common form of extrapulmonary tuberculosis.

201 , resulting in overt pulmonary, pleural, and extrapulmonary tuberculosis.

202 35 (45%) of these 78 patients had extrapulmonary tuberculosis.

203 s lymphadenitis is the main manifestation of extrapulmonary tuberculosis.

204 Extrapulmonary tumors (MCA-205 s.c. and intracranial) th

205 NEU1 and NEU3 proteins to both pulmonary and extrapulmonary vascular endothelia.

206 Together with pulmonary veins, many extrapulmonary vein areas may be the source of initiatio

207 arrhythmia with no pulmonary veins or other extrapulmonary vein site reconnection.

208 rus production and more severe pathology and extrapulmonary virus spread in chickens.

209 H9N2 virus with the G1-like M gene conferred extrapulmonary virus spread in chickens.

210 ia, with subsequent alveolar involvement and extrapulmonary virus spread to the brain.

211 but did not cause lethal disease or exhibit extrapulmonary virus spread.