ライフサイエンスコーパス: eye opening

1 nd continues to change dramatically prior to eye opening.

2 gressive events initiated around the time of eye opening.

3 center to specific stratum of the IPL after eye opening.

4 e retinal ganglion cells from birth to after eye opening.

5 terned sensory activity over 4 days spanning eye opening.

6 shrews reared in the dark from before normal eye opening.

7 nt synapses known to appear in the sSC after eye opening.

8 e, direction selectivity was not detected at eye opening.

9 visual cortex would differ before and after eye opening.

10 ring the course of wave development prior to eye opening.

11 d during a protracted postnatal period after eye opening.

12 es in central visual neurons that is tied to eye opening.

13 eady state in approximately 20 seconds after eye opening.

14 are eliminated over a 3-week period spanning eye opening.

15 ivity in the developing visual cortex before eye opening.

16 esent in cholinergic amacrine cells prior to eye opening.

17 sity, is transiently higher than just before eye opening.

18 uperficial collicular layers beginning after eye opening.

19 ncies of the spontaneous events increased at eye opening.

20 of the rod synaptic terminals just prior to eye opening.

21 cribrosa by P34, coincident with the time of eye opening.

22 s bursting disappears shortly after birth or eye opening.

23 arkedly increased levels were observed after eye opening.

24 ansmission to layer 4 as well as the ear and eye opening.

25 eriod of retinogeniculate development before eye opening.

26 y 8, reaching the adult shape at P13, around eye opening.

27 eas exhibited strong responses shortly after eye opening.

28 liest age sampled (P12), several days before eye opening.

29 Directional tuning stabilized shortly after eye opening.

30 able to control HD responses within 24 hr of eye opening.

31 le the retina with time, and disappear after eye opening.

32 between visually nonresponsive neurons after eye opening.

33 2/3 cells remained as weakly tuned as before eye opening.

34 e throughout the entire visual system before eye opening.

35 ak direction selectivity just before natural eye opening.

36 more pronounced when daily testing began at eye opening.

37 omotor responses in B6 mice at any age after eye opening.

38 x was unaffected by dark rearing from before eye opening.

39 ynchronous and slow-synchronous activity, by eye opening.

40 -OFF RGCs, a process that also occurs before eye opening.

41 ye accelerates RGC laminar refinement before eye opening.

42 t the same age as wild-type, two days before eye-opening.

43 aked at P10-12, corresponding to the time of eye-opening.

44 ely-moving juvenile ferrets before and after eye-opening.

45 nt a substantial spatial rearrangement after eye-opening.

46 tely from birth and reached stable levels by eye-opening.

47 ater than those of the WT mouse, even before eye-opening.

48 At 6 hr after eye opening (AEO), a transient population of currents me

49 Here, they are a consequence of eye opening and are associated with a new wave of synapt

50 ns of molecular diversification occur before eye opening and are therefore experience independent.

51 Y were delayed relative to Sprague-Dawley in eye opening and beam walking.

52 atal day 16 (P16) in the rat pup, just after eye opening and coinciding with the first spontaneous ex

53 Eye opening and increased motor activity after the secon

54 tion to synaptic currents that occurs before eye opening and is closely associated with changes in NR

55 ing wakefulness finally emerges 1-2 d before eye opening and is statistically indistinguishable from

56 eratan sulfates in cornea is concurrent with eye opening and may contribute to corneal transparency.

57 ate dynamic changes in gene expression after eye opening and provide new probes for exploring corneal

58 We found that between eye opening and puberty, release changes from an immatur

59 Pase isoform expression was completed before eye opening and the onset of electroretinographic respon

60 iRNA, miR-132, was rapidly upregulated after eye opening and was delayed by dark rearing.

61 the mouse cornea in vivo within 1-2 days of eye opening and were elevated in a lens cell line expose

62 d cone pathway function rapidly reduced from eye-opening and by P21 became undetectable.

63 ective neurons are unspecific at the time of eye opening, and become to some degree functionally spec

64 s in deep cortical layers (5 and 6) prior to eye opening, and in both deep and superficial layers (2

65 sion in the visual cortex is coincident with eye opening, and it increases until the peak of the crit

66 te neurons at the base of layer 4 (4c) after eye opening, and levels decrease near the end of the cri

67 ioral maturation in SHR, body weight, age at eye opening, and performance in several behavioral tasks

68 at ON [2] and ON-OFF DSGCs are well tuned at eye-opening, and even a few days prior to eye-opening, i

69 t, ectopic contacts appear in the days after eye opening, appearing progressively farther into the ON

70 (P) 9 and begin to break down shortly after eye opening, around P15.

71 cal activity and implicate the period before eye opening as a critical checkpoint.

72 rhythmically hyperactive around the time of eye opening as a result of increased spontaneous glutama

73 ion of retinal wave input ends just prior to eye-opening, as cortex begins to inhibit LGN.

74 ues from Europe and North America provide an eye-opening assessment of long-term neurocognitive, orga

75 Around the time of eye opening at 4 weeks postnatal, the retinotopic arrang

76 Around eye opening at P12, cholinergic neurons were mature-like

77 irection-selective responses are detected at eye opening, before which spontaneous correlated activit

78 eveloping visual cortex several weeks before eye opening; both transmitters have been implicated in p

79 ilar neurochemistry to control retina before eye opening but a subsequent decline.

80 both normal and e,nNOS knockout mice before eye opening but is significantly delayed in the double k

81 Visual experience begins at eye opening, but current models consider cortical circui

82 Grid cell responses develop gradually after eye opening, but little is known about the rules that go

83 time in young RGS7(-/-) mice is prolonged at eye opening, but the phenotype disappears at 2 months of

84 at distinct FF and FB circuits develop after eye opening by rearranging the distribution of excitator

85 lready exhibit highly selective responses at eye opening, can develop feature-specific connectivity i

86 ws started monocular lens wear 24 days after eye opening (days of visual experience [VE]).

87 At eye-opening, dorsal RGCs of all types were more responsi

88 PHR, head-direction cells are present before eye-opening, earliest detected in postnatal day (P)11 an

89 perience and as such does not exist prior to eye opening (EO).

90 ticocollicular terminals form 1-2 days after eye-opening (EO), accompanied by VC-dependent filopodia

91 ually-elicited LFP power was increased after eye-opening, especially in higher frequency bands (>30 H

92 increased and waves abnormally persist past eye opening, eye-specific projections to the LGN desegre

93 We found that in mice, following eye opening, fast-spiking, parvalbumin-positive GABAergi

94 st the rapid maturation of neurochemistry by eye opening followed by functional maturation by P30 in

95 ith the strongest ON responses shortly after eye-opening, followed by an increase in the strength of

96 ibitory responses did not emerge until after eye opening (>P14), when optic tract stimulation routine

97 hat all of the starburst cells tested before eye opening had conspicuous tetrodotoxin-sensitive Na cu

98 hyper-excitability, visual responses before eye-opening had reduced spike rates and an absence of ea

99 vivo and identified a critical period before eye opening in mice when specific binocular features of

100 orsal pre-subiculum (PrSd), before and after eye opening in pre-weanling rats.

101 Outcome was defined by both early eye opening in the 1st week after arrest (either spontan

102 s of PSA significantly decline shortly after eye opening in the adolescent mouse visual cortex; this

103 layers of the primary visual cortex (V1) at eye opening in the awake mouse and identify the features

104 ures of mouse retinal waves from birth until eye opening in unprecedented detail using a large-scale,

105 monosynaptic excitatory synapses even before eye opening in young ferrets, suggesting that visual sig

106 In the few days prior to eye-opening in mice, the excitatory drive underlying wav

107 ray to demonstrate that DSGCs are present at eye opening, in mice that have been reared in darkness a

108 lasticity that commences in infant rats from eye opening, in which daily threshold testing of optokin

109 at eye-opening, and even a few days prior to eye-opening, in rabbits [3], rats [4], and mice [5-8], s

110 Six hours after eye opening, increased dendritic PSD-95 coimmunoprecipit

111 Experiments discriminated between eye opening-induced and age-dependent changes in synapti

112 Their development after eye opening is greatly impeded by visual deprivation.

113 he development of cholinergic neurons before eye opening is independent of the lighting conditions.

114 n, we find that several days of vision after eye opening is necessary for triggering experience-depen

115 neurons for oriented stimuli at the time of eye opening is poor and increases dramatically after the

116 we show that normal visual experience after eye opening is required for V1 neurons to develop a sens

117 Both were eliminated by eye opening, leaving only the mature, short-latency resp

118 y of visual cortical neurons during the post-eye-opening life of an animal.

119 After eye opening, local connectivity reorganized extensively:

120 constant for approximately 10 seconds after eye opening (mean PO2 = 3.9 +/- 0.7) before increasing t

121 At eye opening, neurons in primary visual cortex (V1) are s

122 ready highly selective for visual stimuli at eye opening, neurons responding to similar visual featur

123 At eye opening, Nphp5(-/-) mice exhibited absence of scotop

124 Before eye opening, NR2A is encountered infrequently at postsyn

125 In mice, natural eye opening occurs at the end of the second postnatal we

126 At eye opening, ON directional tuning is mature, whereas OF

127 examination as (1) comatose, (2) arousable (eye opening or attending toward a stimulus), and (3) awa

128 degrees C, neurologic examination showed no eye opening or response to pain, spontaneous myoclonic m

129 was increased, by either a natural stimulus (eye opening) or pharmacological treatment.

130 in membrane excitability occurred just after eye opening (P10), such that all of the starburst cells

131 ojections did not fully innervate dLGN until eye opening (P12), well after the time when retinal inpu

132 apse formation, beginning around the time of eye-opening (P12-P14) and extending through the first po

133 postnatal stages (P3-P7) but increases after eye opening (P14).

134 ps of rats, or daily in groups that began at eye-opening (P15) or 10 days later (P25).

135 Border cells have been recorded around eye-opening (P16), while grid cells do not obtain adult-

136 utput operates within its normal range after eye opening, perhaps to regain proper visual processing

137 citatory and inhibitory inputs during a post-eye-opening period when OS of their spiking responses be

138 Before natural eye opening (postnatal day 14), the excitatory synaptic

139 leus (LGN) of awake behaving ferrets, before eye opening, revealed patterns of spontaneous activity t

140 During week 1 after eye opening, running increases responsiveness in layers

141 ly stimulated LTP, in the juvenile sSC after eye opening, selectively involves the addition or stabil

142 predictor of poor outcome as measured by no eye opening (specificity, 100% [95% confidence interval

143 But, around eye-opening, spontaneous and visually evoked activity in

144 re is major synchronous reorganization after eye opening, suggesting a crucial role for visual experi

145 However, here we show that at eye-opening the preferred directions of both ON and ON-O

146 Here we show in ferrets that at eye opening, the cortical response to visual stimulation

147 Upon eye opening, the firing direction of these cells is anch

148 Following eye opening, the HD system matures rapidly, as more cell

149 In rodents, eye opening, the onset of pattern vision, triggers a rap

150 Before eye opening, the pattern of amino acid immunoreactivity

151 After eye opening, the space between the two cholinergic bands

152 After eye opening, the spatiotemporal structure of neural acti

153 We also find that 1 to 2 weeks after eye opening, there is a surge (>4-fold) in the frequency

154 of cortical feedback to V1 is present before eye opening, there is major synchronous reorganization a

155 es from the onset of responsiveness prior to eye-opening, through age equivalents of human juveniles.

156 of direction selectivity around the time of eye opening to identify the locations within the cortica

157 ake, freely viewing ferrets from the time of eye opening to maturity.

158 ticity, mice underwent MD during the pre-CP [eye-opening to postnatal day (p)17] or CP (p22-p25), and

159 MD of ipsilateral inputs from before eye opening (to reduce competitive interactions) did not

160 extended period of development, starting at eye opening, to measure receptive field properties and b

161 l ERG responses improved simultaneously from eye-opening until adult levels were achieved at approxim

162 inocular deprivation from before the time of eye-opening up-regulated spine motility during the peak

163 n postmitotic mouse cones, between birth and eye opening, using serial block-face electron microscopy

164 vity emerges in the days and weeks following eye opening via a process that requires visual experienc

165 At the time of eye opening, visual cortical neurons in the ferret exhib

166 Third, between P11 and P14 (eye opening) we observed propagating activity that was a

167 mals that were dark-reared until the time of eye opening, we found that individual neurons exhibited

168 The changes occurring following eye opening were retarded by visual deprivation.

169 l a distinct period in development, prior to eye opening, when high levels of SNAP-25-IR are selectiv

170 After eye opening, when inhibitory responses are fully develop

171 ntation, direction, and spatial frequency at eye opening, which are similar across cortical layers.

172 This effect peaks after eye opening, which indicates a function for serotonergic

173 pressed at low levels in the cornea prior to eye opening, while markedly increased levels were observ

174 lk of synaptic refinement around the time of eye opening, while sensory experience is important for t

175 alleviate") and 3 ES signs ("abrupt onset," "eye-opening/widening," and postictal "confusion/sleep")

176 Combined gp120+Tat effects were noted for eye opening with potential interactive effects of gp120