1 We first demonstrate the fundamental problem 
faced by a host: The presence of a genetically diverse m
 
     2  10 years, and discusses the main challenges 
faced by a rapidly expanding system, in particular the c
 
     3                                   Challenges 
faced by adolescents fall into the realm of functional l
 
     4                       The navigational tasks 
faced by adults and juveniles differ fundamentally, beca
 
     5 ar energy, free ribosomes, and proteins, are 
faced by all living cells and we construct a mechanistic
 
     6 ce between anergy and activation, a decision 
faced by all T cells undergoing TCR stimulation.        
 
     7 ship between the specific cognitive problems 
faced by an individual patient, their stage of disease a
 
     8 diologic literature as they relate to issues 
faced by anesthesiologists.                             
 
     9 owledge about this parasite and the problems 
faced by animal health agencies in controlling the disea
 
    10                        A universal challenge 
faced by animal species is the need to communicate effec
 
    11 comotion is one of the major energetic costs 
faced by animals and various strategies have evolved to 
 
    12 EMENT Among the most basic survival problems 
faced by animals is balancing the need to seek food and 
 
    13                            A central problem 
faced by animals traveling in groups is how navigational
 
    14 tanding the complexity of the acoustic scene 
faced by animals vocalizing in groups.                  
 
    15                      The principal challenge 
faced by any color vision system is to contend with the 
 
    16  used to select these genes, the common task 
faced by any researcher is to translate these lists of g
 
    17 tes understanding of psychosocial challenges 
faced by AYAs when diagnosed with and treated for cancer
 
    18                       Many of the challenges 
faced by AYAs with a diagnosis of malignant disease are 
 
    19                Hypoxia is a common challenge 
faced by bacteria during associations with hosts due in 
 
    20 iew will inform clinicians of the challenges 
faced by basic scientists and clinicians when treating b
 
    21    In addition to the immediate consequences 
faced by biota living in roaded landscapes, road effects
 
    22  opportunities as well as new challenges are 
faced by both the surgeon and the anesthesiologist.     
 
    23 nergetic, biosynthetic and toxicity barriers 
faced by cancer cells.                                  
 
    24          We will also discuss the challenges 
faced by candidate gene studies, such as differences in 
 
    25 s among the most common psychiatric problems 
faced by children and adolescents, anxiety disorders hav
 
    26 ot correspond to the most important barriers 
faced by children.                                      
 
    27 iders must be sensitive to multiple barriers 
faced by chronic sarcoid patients; acknowledging depress
 
    28 luster, it can overcome many of the problems 
faced by classical clustering algorithms.               
 
    29 highlighted the many challenges and dilemmas 
faced by clinicians assessing persons with disorders of 
 
    30        These failures reflect the difficulty 
faced by clinicians attempting to address multiple issue
 
    31 tifying emerging pathways and the challenges 
faced by clinicians during clinical trials, the IDIBELL 
 
    32 aightforward, however, because of challenges 
faced by clinicians, health systems, and consumers.     
 
    33 mprinting to overcome some of the challenges 
faced by conventional protein imprinting.               
 
    34 le inhibitors represent important challenges 
faced by current anti-AXL therapeutics.                 
 
    35 me the safety and energy density limitations 
faced by current lithium-ion technology.                
 
    36 ity is an important and frequent fluctuation 
faced by D. vulgaris in its natural habitat.            
 
    37 veloped specifically to answer the questions 
faced by decision makers are called pragmatic or practic
 
    38              However, significant challenges 
faced by developers as a product moves from the purely t
 
    39 ved novel solutions to the common challenges 
faced by dividing eukaryotic cells.                     
 
    40                          The central problem 
faced by DNA binding proteins is how to select the corre
 
    41 tax deduction may be too low to defray costs 
faced by donors, lack of public awareness about the exis
 
    42                     Alleviating the problems 
faced by dying persons and their families has drawn subs
 
    43 ighlighting the different types of challenge 
faced by each country.                                  
 
    44 n to measure, by image shift, the deflection 
faced by each group of rays as they emerge from the obje
 
    45 , pressures exerted by people who need care) 
faced by economies with high, middle, and low incomes, p
 
    46 nch to bedside." We also comment on the task 
faced by electrophysiologists and HF specialists as they
 
    47  strategies for solving a biological problem 
faced by essentially all metazoans: how to generate two 
 
    48 tant to identify the barriers and challenges 
faced by families as a result of genetic screening for S
 
    49             An important technical challenge 
faced by fluorescence microscopy-based measurement of ol
 
    50 ue to programmatic and structural challenges 
faced by healthcare systems in low-income countries.    
 
    51 is variation lies in a fundamental trade-off 
faced by helpers: by working harder, they increase the i
 
    52                          Overcoming barriers 
faced by homeless individuals in accessing TB treatment 
 
    53 sociated with challenges distinct from those 
faced by hospitals.                                     
 
    54                        A fundamental problem 
faced by humans is learning to select motor actions base
 
    55 isparities in patient choice and competition 
faced by individual centers emerged.                    
 
    56  is critical to understanding the trade-offs 
faced by individual nodes in a network.                 
 
    57  the identification of particular challenges 
faced by individuals after treatment for CRC.           
 
    58 his paper provides an overview of challenges 
faced by industry, regulators, and society in general in
 
    59 lycemia is a common and serious complication 
faced by insulin-treated diabetic patients.             
 
    60 eveloped a taxonomy of the rationing choices 
faced by intensivists as a framework for ethical analysi
 
    61  It reflects on many of the ethical tensions 
faced by internists and their patients and attempts to s
 
    62 ends, we summarize methodological challenges 
faced by investigators, and the tools, techniques and an
 
    63                  Despite numerous challenges 
faced by investigators, study staff, and participants, i
 
    64 of human traits, highlighting the challenges 
faced by investigators--in particular, insufficient link
 
    65 n the web-is a fundamental computing problem 
faced by large-scale information retrieval systems.     
 
    66            This situation is similar to that 
faced by Leeuwenhoek in the seventeenth century, whose w
 
    67                 The authentication issue was 
faced by Linear Discriminant Analysis (LDA) and Soft Ind
 
    68 implemented to tackle the diverse challenges 
faced by local health-care systems.                     
 
    69 ons that mimic the intracellular environment 
faced by M. tuberculosis.                               
 
    70 nder widely varying environmental conditions 
faced by maize as it was migrated away from its domestic
 
    71 children and adolescents is a vexing problem 
faced by many clinicians.                               
 
    72                   Surprisingly, the problems 
faced by many dyslexic children are by no means confined
 
    73 databases is still one of the major problems 
faced by many life sciences laboratories.               
 
    74 cyclic peptide format overcomes a limitation 
faced by many peptide leads and appears to be suitable f
 
    75                        The extent of threats 
faced by marine systems, and their resilience to them, r
 
    76 way, circumventing the difficulties that are 
faced by maximum likelihood methods.                    
 
    77   A critical evaluation of the problem space 
faced by medicinal chemists and cognitive models of cate
 
    78 ubstrates is a ubiquitous selection pressure 
faced by microbes, yet intracellular trade-offs can prev
 
    79             One of the limitations currently 
faced by microbial electrochemical cell (MXC) technologi
 
    80 r experiments reveal a fundamental challenge 
faced by microbial strains that live in porous environme
 
    81 his ability, likely a vicious cycle scenario 
faced by microglia in Parkinson's disease.              
 
    82 perature represent one of the major stresses 
faced by microorganisms as they affect the function of t
 
    83 ctionally and reflects the unique challenges 
faced by motors that move nucleosomes.                  
 
    84 ing the adaptation and mitigation challenges 
faced by multiple sectors in California.                
 
    85                                     The task 
faced by MutM of locating rare oxoG residues embedded in
 
    86       These findings redefine the challenges 
faced by nature in controlling the biosynthesis of compl
 
    87 rpassed efficacy has intensified the dilemma 
faced by neurologists treating people with epilepsy, and
 
    88  essential to overcome the reported barriers 
faced by nurses internationally.                        
 
    89 s after therapy is one of the major problems 
faced by oncologists.                                   
 
    90                           Many of the issues 
faced by Ontario are relevant beyond Canada, including i
 
    91 gulation of cell shape is a common challenge 
faced by organisms across all biological kingdoms.      
 
    92 re specific predictions about the trade-offs 
faced by organisms in the allocation of bioenergetic and
 
    93 ave functions that correlate with challenges 
faced by OSNs.                                          
 
    94 es unique challenges and issues beyond those 
faced by other age groups.                              
 
    95 ology (ASM) in meeting the future challenges 
faced by our discipline.                                
 
    96 natural selection to solve adaptive problems 
faced by our hunter-gatherer ancestors.                 
 
    97 e tradeoff between consumption and longevity 
faced by parasites.                                     
 
    98 eview identifies and explores the challenges 
faced by parents and their (non)affected or at risk chil
 
    99 ed under iron limitation, a common condition 
faced by pathogens inside the host.                     
 
   100    This review will highlight the challenges 
faced by patients and couples and reveal the tremendous 
 
   101  social stigma and embarrassment that may be 
faced by patients.                                      
 
   102 vestments to address the specific challenges 
faced by people living in remote areas.                 
 
   103 ng and mitigating the barriers to employment 
faced by people with CF.                                
 
   104 for understanding communication difficulties 
faced by people with hearing loss.                      
 
   105                             These challenges 
faced by people with zoonotic tuberculosis might not be 
 
   106 unting diagnostic and therapeutic challenges 
faced by periodontists.                                 
 
   107 i) deficiency is a major nutritional problem 
faced by plants in many agro-ecosystems.                
 
   108 driven by evolutionary convergent trade-offs 
faced by plants.                                        
 
   109 n cohort study was to define the cancer risk 
faced by PMS2 mutation carriers.                        
 
   110 icitly define an ecological genetic obstacle 
faced by populations of an exotic species on its way to 
 
   111 o give an overview of some of the challenges 
faced by preclinical stroke research, and suggest potent
 
   112 weak health systems, heightens the challenge 
faced by prescribers.                                   
 
   113 operating conditions, overcoming limitations 
faced by previous healing agents such as chitosan agglom
 
   114 ple allows the system to overcome challenges 
faced by previously reported reusable sensors, such as e
 
   115 on Center (REC) program to ease the barriers 
faced by primary care physicians and rural and critical-
 
   116 ed as an analog of natural foraging problems 
faced by primates.                                      
 
   117 recognition and management of ongoing issues 
faced by prostate cancer survivors may impact the overal
 
   118 Inadequate data exist on the health problems 
faced by prostituted children, who are at high risk of i
 
   119 g non-sequence-specific ligands is a problem 
faced by proteins in all organisms.                     
 
   120              That is, much of the difficulty 
faced by providers after providing critical care service
 
   121 gued that the level of epistemic uncertainty 
faced by regulators has substantially decreased.        
 
   122                                The challenge 
faced by research into the genetic basis of complex dise
 
   123                          The major challenge 
faced by researchers attempting to complete mutation ana
 
   124 t an introductory overview of the challenges 
faced by researchers in developing valid and reliable bi
 
   125      Here we reflect on analogous challenges 
faced by researchers in infectious diseases.            
 
   126 amine the approaches used and the challenges 
faced by reviewers when nonrandomized studies are includ
 
   127 ectives that focus on the special challenges 
faced by scientists in discovering potential new chemica
 
   128  the entire human genome, a major difficulty 
faced by scientists in planning costly population-based 
 
   129 our algorithm overcomes the intrinsic issues 
faced by sequence similarity-based methods, when ortholo
 
   130 ular in their design and overcome challenges 
faced by small-molecule organic materials for battery ap
 
   131 n of disease and the increased risk of death 
faced by smokers.                                       
 
   132 alistic turbulent environments-a common task 
faced by species that rely on olfactory cues for navigat
 
   133 lternatives, given some of the disadvantages 
faced by spectrophotometric methods such as the use of e
 
   134                                One challenge 
faced by stem cell biologists is the bioengineering of a
 
   135                  The logistical difficulties 
faced by steroid receptors or other transcription factor
 
   136 have been achieved in cancer control, issues 
faced by survivors have become increasingly relevant.   
 
   137 at somatic distress is the biggest challenge 
faced by survivors long after HCT.                      
 
   138  been made in recognizing many of the issues 
faced by survivors, gaps in comprehensive surveillance a
 
   139                         A critical challenge 
faced by sustainability science is to develop strategies
 
   140                                    A dilemma 
faced by teachers, and increasingly by designers of educ
 
   141                        A fundamental problem 
faced by the auditory system of humans and other vertebr
 
   142 t important and poorly understood challenges 
faced by the auditory system.                           
 
   143 rrent major technical and economic challenge 
faced by the biofuels industry.                         
 
   144 nto perceptual decisions is a core challenge 
faced by the brain.                                     
 
   145 ls to mimic the real-time estimation problem 
faced by the brain.                                     
 
   146 , structure, accomplishments, and challenges 
faced by the Canadian National Transplant Research Progr
 
   147 t current particle size metrology challenges 
faced by the chemical industry due to these emerging num
 
   148 utations presents one of the main challenges 
faced by the clinical genetics community today.         
 
   149 t will highlight contemporary AST challenges 
faced by the clinical laboratory, and propose some solut
 
   150                               The challenges 
faced by the cooperative groups to the incorporation of 
 
   151 sfactorily tackle great challenging problems 
faced by the density functional theory recently discusse
 
   152                  One of the major challenges 
faced by the developing visual system is how to stably p
 
   153 rief analyses were presented of the problems 
faced by the European neuroscience community in its atte
 
   154 onsider the future directions and challenges 
faced by the field of metabolic network flux phenotyping
 
   155  the ability to resolve key ethical problems 
faced by the field of psychiatry.                       
 
   156 m highlights the data-aggregation challenges 
faced by the field, suggests potential collaborative sol
 
   157 in kidney donors has been compared with risk 
faced by the general population, but the general populat
 
   158  primary environmental and social challenges 
faced by the global community.                          
 
   159  to be one of the most ubiquitous conditions 
faced by the healthcare team, and has a significant emot
 
   160                               The challenges 
faced by the Israeli health-care system include a growin
 
   161 ng time is one of the fundamental challenges 
faced by the nervous system in mediating behavior.      
 
   162 th its elegant formalization of the problems 
faced by the nervous system, it promises to become a maj
 
   163 ncy sensory information is a crucial problem 
faced by the nervous system.                            
 
   164                   One of the main challenges 
faced by the nuclear industry is the long-term confineme
 
   165 pments in three areas of pediatrics commonly 
faced by the office practitioner.                       
 
   166 gation in three areas of pediatrics commonly 
faced by the office practitioner.                       
 
   167 tanding economic and environmental challenge 
faced by the oil and gas industries.                    
 
   168 ion delays simplifies computational problems 
faced by the optic tectum.                              
 
   169 irations of its leadership and the realities 
faced by the organisation on the ground.                
 
   170                     A significant difficulty 
faced by the pharmaceutical industry is the initial iden
 
   171            Some of the higher risk variables 
faced by the practitioner are identified for submission 
 
   172                        Because many problems 
faced by the primate brain in the control of movement ha
 
   173  are consistent with the multiple challenges 
faced by the program in these regions as a result of con
 
   174               We also discuss the challenges 
faced by the resource given the explosive growth in sequ
 
   175 ing such a fact, one of the major challenges 
faced by the scientific community is to find ways to pre
 
   176              One of the many harmful factors 
faced by the skin is solar UV radiation, which damages s
 
   177 ny nutritional stresses and other challenges 
faced by the spirochete in ticks and animal reservoirs. 
 
   178 ct recognition which belies the difficulties 
faced by the system when learning in natural visual envi
 
   179                          Such challenges are 
faced by the US/Europe, but are particularly acute in de
 
   180 nat-IG under various conditions likely to be 
faced by the user, and show that its network-based appro
 
   181  than the ecological constraints to invasion 
faced by the virus population.                          
 
   182                                 A basic task 
faced by the visual system of many organisms is to accur
 
   183 ce twice the risk of mortality and morbidity 
faced by their younger peers.                           
 
   184                  One of the major challenges 
faced by therapeutic polypeptides remains their invasive
 
   185 of human disease and evaluate the challenges 
faced by these approaches.                              
 
   186 for understanding the evolutionary pressures 
faced by these lineages.                                
 
   187 crease awareness of the adherence challenges 
faced by these patients, we have reviewed the published 
 
   188 , giving a sense of the "design" constraints 
faced by these receptors.                               
 
   189  discuss technical and scientific challenges 
faced by these systems before they are widely adopted by
 
   190                      The principal challenge 
faced by these technologies is the need for high-through
 
   191             We also highlight the challenges 
faced by this field by the potential damage caused by co
 
   192       Contributing factors to the challenges 
faced by this group include distinctive disease biology,
 
   193 ral history and of other lifestyle decisions 
faced by this model organism.                           
 
   194                  One of the major challenges 
faced by this rapidly growing field lies in data analysi
 
   195            It considers some of the problems 
faced by those who try to interpret the taxonomy and sys
 
   196 technique overcomes one important limitation 
faced by traditional GC and even comprehensive 2D gas ch
 
   197 meaningful way will be one of the challenges 
faced by transplant clinicians in the future.           
 
   198 ow to reflect new challenges and imperatives 
faced by trauma surgeons.                               
 
   199          Biology, chemistry and medicine are 
faced by tremendous challenges caused by an overwhelming
 
   200 poptotic resistance and to model a challenge 
faced by tumor cells during metastatic dissemination, we
 
   201  of this study is to document the challenges 
faced by uninsured, poor Mexican families when attemptin
 
   202                The advantages and challenges 
faced by users of the Bayesian approach are also discuss
 
   203 ong different IDU cohorts and the challenges 
faced by vaccines in protecting against this mode of inf
 
   204                               The challenges 
faced by vaccinologists to create the next generation of
 
   205 evention is reviewed in the context of risks 
faced by women with resected breast cancer.             
 
   206 ecades, much has been written about barriers 
faced by young people in accessing health care.