ライフサイエンスコーパス: fail to

1 Two routes that failed to access eupalinilide E were triaged either as a

2 ding coral health into the future, but often fail to account for the complex ecological and biogeoche

3 rgans is compounded by donation metrics that fail to account for the total pool of possible donors, l

4 e found that lower-level, absolute judgments failed to account for higher-level, relative/ordinal jud

5 oduction with deuterated carbon sources have failed to account for roughly half of NADPH's redox acti

6 rweight risk paradox may result in part from failing to account for central adiposity, rather than re

7 Our results demonstrate that failing to account for nonbreeders in population studies

8 ate often applied in institutional settings, fails to account for complex factors that may influence

9 cient CD8(+) tumour-infiltrating lymphocytes failed to accumulate in tumours, resulting in greater ra

10 elies on phase retrieval algorithms that can fail to accurately reconstruct the defect network.

11 ce and assemble new species' genomes de novo fail to achieve the ultimate endpoint to produce contigs

12 ent screening and treatment strategy for IDA fails to achieve this goal for 3 reasons.

13 arated by <25 nm where conventional scanning failed to acquire sufficient signal.

14 Aged CPCs fail to activate mitochondrial biogenesis and increase p

15 e/threonine protein kinase upstream of AMPK, failed to activate AMPK and sustain energy homeostasis a

16 mate concentrations that exceeded 250 microM failed to activate cell signaling.

17 strate that in the absence of MRAP2, fasting fails to activate agouti-related protein neurons.

18 We report here that sulforaphane treatment fails to activate NRF2 and prevent PPK in female Krt16(-

19 MuSh and the CWI pathways are deleted, cells fail to adapt to compressive stress, and all cells lyse

20 ppress inflammation and symptoms of ACD, but fail to address the underlying immune dysfunction.

21 Traditional treatments for breast cancer fail to address therapy-resistant cancer stem-like cells

22 nsmission, such loss-of-function experiments fail to adequately distinguish between the roles played

23 Loss of either protein alone failed to affect Wnt signaling levels or tissue homeosta

24 As a consequence, HVEM-deficient recipients failed to afford protection against respiratory reinfect

25 In contrast, treatment with dynasore failed to alter the surface membrane expression of SK2 c

26 hrenia, current treatment strategies largely fail to ameliorate these impairments.

27 nant IL-27 in Treg-specific Il27ra(-/-) mice fails to ameliorate the disease even in the presence of

28 ents are based on a level of generality that fails to appreciate the specific conditions of the Mongo

29 ted, unassembled alpha-globin molecules that failed to assemble with beta-globin were selectively ubi

30 omplete absence of liver invasion as mutants fail to attach to host cells.

31 f under-sampled glycoforms and of those that failed to be identified by searching against a predefine

32 ed that two E.coli enzymes, EcTSR and EcGCL, failed to be targeted into rice chloroplasts by the comm

33 one-third of newly diagnosed epilepsy cases fail to become seizure-free in response to antiseizure d

34 mutants were defective in PI3K because they failed to bind the enzyme and bring the activity to the

35 ro motif had been replaced with Ala residues fails to bind hemin with high affinity.

36 luster in purified human mitoNEET and Miner1 fails to bind nitric oxide, a single mutation of Asp-96

37 However, most monitoring systems fail to capture these small scale variations.

38 an populations into open and isolated groups fails to capture the actual relations among their genomi

39 ing, repetitively displayed allergen on VLPs failed to cause mast cell activation.

40 r efficient maturation, but recombinant Csm5 fails to cleave crRNAs in vitro.

41 ta1059-1063, but not CaValpha2delta1 G1060A, failed to co-immunoprecipitate with CaV1.2.

42 transcribed genes also loop and crumple yet fail to coalesce.

43 ting common alleles found in cancer patients failed to complement in these assays.

44 iously identified putative de novo mutations failed to complement yeast strains lacking the EEF1A ort

45 the latest replicating regions occasionally fail to complete endoreplication, resulting in underrepl

46 Failing to complete chemotherapy adversely affects survi

47 In the absence of endogenous Treg, IVIg failed to confer protection against AHR and airway infla

48 Folr1-deficient neural plate cells fail to constrict, resulting in widening of the neural p

49 In contrast, a null mutant in gamma34.5 failed to control IRF3 phosphorylation due to an inabili

50 Traditional graphs and charts failed to convey the complex shapes of brain structures

51 However, previous research has failed to convincingly demonstrate the specificity of th

52 vent the progression of liver diseases, they fail to cure the viral infection.

53 Compared with control cells, they failed to decidualize in vitro as demonstrated by morpho

54 Pre-treatment with ABT-627 failed to decrease renal ER stress and apoptosis in ETB

55 Such cements remain in the tooth and fail to degrade and thus normal mineral volume is never

56 wed cases in which normally functioning ICDs failed to deliver timely therapy for VF from April 2015

57 use of FE is unknown, and prior studies have failed to demonstrate a primary abnormality in the eosin

58 TP (cholesteryl ester transfer protein) have failed to demonstrate a reduction in risk for coronary h

59 anconi anemia (FA) gene therapy studies have failed to demonstrate engraftment of gene-corrected hema

60 at quantized triangular sizes, but they have failed to demonstrate production and control of isolated

61 Till date, studies have failed to demonstrate that preventing gastroesophageal r

62 This well-conducted trial failed to demonstrate that the intervention kept childre

63 guely represents evolutionary relationships, fails to denote major events in the history of life, and

64 ated, but current assays for early detection fail to detect >50% of infected neonates, and 9-month fo

65 ter significant injury has already occurred, fail to detect chronic subclinical inflammation that can

66 t methods commonly employed in the field may fail to detect or else conflate generalization that mani

67 EIC peaks that they do and in what ways they fail to detect real compounds.

68 Standard proteomics protocols fail to detect them as d/l substitutions do not affect t

69 included the usual diet of </=600 mg Ca/d.We failed to detect a statistically significant difference

70 recision on the proteins for which threading failed to detect any DCDs.

71 d at 3 h of the in vitro antifungal exposure failed to detect C. glabrata isolates with echinocandin

72 We failed to detect consistent distance-abundance relations

73 erformed automated segmentation of songs but failed to detect the proposed rhythm.

74 us report indicated that GPR55 knockout mice fail to develop mechanical hyperalgesia, suggesting a pr

75 DBA/2 mice failed to develop antibodies to citrullinated fibrinogen

76 bit serum that was taken before immunization failed to develop any of these changes.

77 V600E) expression induced by the same method failed to develop LCH-like neoplasms, suggesting that ea

78 or (A-P) symmetric stiffness gradient, which fails to develop in elongation-defective mutants.

79 c (HbA1c)/fasting plasma glucose (FPG) alone fail to diagnose or miscategorize up to 40% of individua

80 DLC and SB algorithms failed to diagnose 4 (44%) and 3 (33%) patients with gen

81 nic stem cells with deletion of EZH1 or EZH2 fail to differentiate into ectoderm lineages.

82 e that nephron progenitor cells lacking Pax2 fail to differentiate into nephron cells but can switch

83 Pre-osteoblasts fail to differentiate leading to severe intramembranous

84 nductance responses in OCD patients (n = 43) failed to differentiate during reversal compared with he

85 Unlike intact SAA1alpha, these SAA fragments failed to directly chemoattract neutrophils and monocyte

86 eward and no-reward levers; however, KO mice failed to discriminate based on relative quantity-reward

87 Mutant Nrp2 islets aggregated centrally and failed to disperse radially.

88 lmonary embolism, physiological fibrinolysis fails to dissolve thrombi acutely and r-tPA (recombinant

89 the case of S. cerevisiae, the OD600 method failed to distinguish between cytotoxic and cytostatic d

90 using oligonucleotide microarrays have often failed to distinguish these two phenotypes.

91 sion bottleneck sizes, whereas other methods fail to do so.

92 ted with DNA from neoplastic cells, but they failed to do so in 80 to 90% of the transfections.

93 ade, whereas FMT from nonresponding patients failed to do so.

94 impairing MC accumulation within the CNS and failed to drive clinical improvement.

95 found that known membrane insertion pathways fail to effectively engage tail-anchored membrane protei

96 ecruit PI3K activity like the wild type, but fail to elevate the cellular level of PIP3, the product

97 nomeric Env immunogens designed to date have failed to elicit such antibodies.

98 4), angiotensin-(5-7), and angiotensin-(3-4) failed to enhance GSIS.

99 However, these tests fail to equal culture's sensitivity with sputum smear mi

100 ervations further suggested that Afh mutants failed to exhibit the necessary phenotypic plasticity fo

101 Standard accretion models fail to explain its luminosity, even assuming beamed emi

102 tested NSAIs, LMEs activity and biosorption failed to explain the observed removal.

103 ctor CD8(+) T cells (Tc17) produce IL-17 and fail to express cytotoxic genes.

104 adients, likely due to disorganized MTs that failed to extend into the peripheral domain and enter fi

105 ns why wild population studies may generally fail to find strong support for interactions between inb

106 This population- and family-based study failed to find support for a causal effect of smoking du

107 ge fraction of NM-II and myosin-1c molecules fail to fold in the absence of UNC-45a.

108 ER-Golgi contacts fail to form during ER stress in cells lacking Nvj2p.

109 fish embryos without maternally provided vg1 fail to form endoderm and head and trunk mesoderm, and c

110 ll PECs proliferated less, lost polarity and failed to form villous protrusions and floating cysts.

111 ents and had normal A11 localization despite failing to form immature virions.

112 We show that, in isolation, IL-12alpha fails to form its native structure but, instead, misfold

113 Furthermore, stm6 failed to fully activate chlororespiration and cyclic el

114 response maxima sites using the DR5 promoter fails to fully rescue lfs plants, suggesting that additi

115 o WT muscles, suggesting that dyW-/- muscles fail to generate enough muscle cells to sustain fetal my

116 ver, many subunit vaccines under development fail to generate robust LLPC responses, and therefore a

117 YAP/TAZ to enter S-phase and, without them, fail to generate sufficient SCs for timely axon sorting.

118 strain proved difficult as transfer cultures failed to grow after multiple rounds of media transfer.

119 te-directed T1D interventions tested to date failed to halt beta cell demise.

120 d the input-output function in sham rats, it failed to have an effect in HF rats.

121 Recent studies fail to identify a causative organism in more than 50% o

122 regulated exocytosis, but previous work has failed to identify a clear physiological defect in mice

123 Interestingly, two different shRNA screens failed to identify a single TP53 target gene required fo

124 Whole-exome sequencing in 997 subjects failed to identify any large-effect coding alleles of lo

125 ethicillin-resistant S. aureus (MRSA), which failed to identify from 0 to 41% of tested mecC-harborin

126 g in two prospective randomized DLBCL trials failed to identify prognostic subgroups, whereas dual ex

127 This approach further fails to identify individuals who experience the majorit

128 sly applied dsRNAs, either degrading them or failing to import them into the cytoplasm.

129 nclusion The addition of palifosfamide to CE failed to improve survival in ES SCLC.

130 improved WHO compliance less (P < 0.001) and failed to improve technical performance.

131 was not observed in patients whose epiphora failed to improve.

132 mor resection and (neo)adjuvant chemotherapy fails to improve a poor prognosis.

133 pt, a decoy receptor that binds soluble TNF, fails to improve disease.

134 in the atria, and truncated MyBP-HL protein failed to incorporate into the myofilament.

135 so increased basal mROS expression, but they failed to increase production after pneumococcal challen

136 key ISR gene targets such as Atf5 and Trib3 failed to increase.

137 ) and dominant-negative rab5, ER cholesterol fails to increase when mTORC1 activity is low, and SREBP

138 However, most of them, if not all, fail to induce a clear-cut degradation of PE samples, sh

139 Furthermore, IgE autoantibodies fail to induce BP in eosinophil-deficient mice, confirmi

140 phils with a genetic defect in NADPH oxidase fail to induce either actin and tubulin polymerization o

141 59, 290 and 569R) abolished JNK1 binding and failed to induce apoptosis.

142 esponses in rabbits and macaques, but so far failed to induce broadly neutralizing antibodies.

143 these cells revealed that CDK4/6 inhibition failed to induce cell-cycle arrest or senescence.

144 tained in BAC transgenic Foxp3.LuciDTR4 mice failed to induce complete rejection of HCmel12 melanomas

145 (EMT) of ovarian cancer cells in vivo, STAT4 failed to induce EMT directly in vitro, suggesting that

146 ioned media from IL-4-stimulated macrophages failed to induce expression of thermogenic genes, such a

147 ued to exhibit low liver Hamp at 8 weeks and failed to induce Hamp in response to Bmp6 in primary hep

148 s had high expression of SIRT1 and SIRT7 and failed to induce p-FOXO3 and apoptosis in response to LP

149 However, several studies failed to induce performance deficit implementing this a

150 ined high levels of mucosal colonization but failed to induce robust vaginal immunopathology (neutrop

151 volved in Fas-mediated cell death, and Erdr1 fails to induce apoptosis in Fas-deficient cells.

152 ereas intestinal Rorc(fm-) ILC1s or NK cells fail to inhibit tumor progression.

153 BMS-986126 failed to inhibit assays downstream of MyD88-independent

154 veral EGFR-mediated cancer models, cetuximab failed to inhibit downstream signaling or to kill cells

155 In in vitro studies, Nogo-A-Fc failed to inhibit growth of lizard RGC axons.

156 418A), a mutant that does not bind to eIF4A, failed to inhibit Sin1 translation, and consequently fai

157 t docked poorly in the GtfC catalytic domain failed to inhibit the activity of Gtfs and S. mutans bio

158 ited all three mutants by as much as 80% but failed to inhibit WT-GC-B.

159 These embryos fail to initiate timely MZT, undergo cell-cycle pause, a

160 ons exited, and Schwann cells and astrocytes failed to integrate.

161 Previous studies have failed to investigate the role of natural regulatory T c

162 ics, which targets bacterial topoisomerases, fails to kill bacteria that have grown to high density;

163 es the effects of SCCRO on abscission, as it fails to localize to the midbody in SCCRO-deficient cell

164 We show that early AnkG-deficient nodes fail to mature and undergo rapid destabilization.

165 ent with these findings, viral glycoproteins fail to mature in SPCA1-deficient cells preventing viral

166 gent showed why BCl3, in contrast to ClBcat, failed to mediate the complete the cyclization/demethyla

167 rently the key player in the field, yet they fail to meet the commercial demands of scalability and e

168 ll 4 claims-based 30-day mortality measures, failed to meet 1 or more criteria.

169 taminated colorectal surgery, the use of IPA failed to meet criterion for noninferiority for overall

170 Classic drug development strategies have failed to meet the urgent clinical needs in treating inf

171 Here we report that many MPAs failed to meet thresholds for effective and equitable ma

172 orated with a shRNA targeting IGF-1 receptor failed to migrate to the upper cortical layers and accum

173 However, these same mutations failed to modify the toxicity of (GR)50, suggesting that

174 Thus, cells that cannot make ceramides fail to modulate their growth rate or size in response t

175 i-A(H1N1)pdm09 HA monoclonal antibodies that failed to neutralize viruses isolated after 2013 from a

176 low-up studies from independent laboratories failed to observe such an effect.

177 tro in the presence of choline, whereas this failed to occur in Chdh(-/-) oocytes, directly demonstra

178 MARY OF BACKGROUND DATA: IMA techniques have failed to penetrate routine practice due to limitations,

179 eories of demographic/family change, the SDT failed to predict many contemporary patterns of change/d

180 Preclinical animal testing often fails to predict adverse outcomes arising from sequentia

181 lso associated with short-term mortality, it fails to predict development of RD, HRS, and ACLF.

182 intervention if other therapeutic modalities fail to prevent progression.

183 EC titers within the bladder, this treatment failed to prevent relapsing bacteriuria.

184 plemented with geranylgeraniol, pitavastatin failed to prevent tumour growth.

185 r spirochetemia induced by DeltaVlsE and yet failed to prevent WT-induced spirochetemia.

186 , we show that tomato leafless (lfs) mutants fail to produce cotyledons and leaves and grow a naked p

187 Here, we demonstrate that bdMphi fail to produce nitric oxide (NO) or upregulate inducibl

188 torsinA knockdown in the immature cerebellum failed to produce dystonia.

189 , heterozygous mpk6 mutant plants completely failed to produce homozygous mpk6 seeds.

190 th target cells, Zap70(low)Syk(low) NK cells failed to produce IFN-gamma and lysed target cells at on

191 TLR3-, TRIF-, and IRF3-dependent manner but failed to produce IFNbeta.

192 onventional cap analogue (7-methylguanosine) failed to produce ITGA4 protein, but exogenous ITGA4-mRN

193 n) and food-seeking control experiments also failed to produce the same effects.

194 ated SOD1 fibrils to organotypic spinal cord failed to produce the SOD1 inclusion pathology that typi

195 Cells lacking this activation mechanism fail to proliferate after hyperosmotic stress.

196 sendothelial monocyte migration in vitro and failed to promote leukocyte recruitment when added to mu

197 Sin3B-deleted HSCs accumulate and fail to properly differentiate following transplantation

198 ifferent immunodominant vaccine antigens can fail to protect for opposite reasons, highlighting a maj

199 ust levels of HA inhibition (HI) titers, but failed to protect against five different heterologous le

200 ally tested and licensed dengue vaccine that failed to protect seronegative individuals from breakthr

201 rticles in 4 ophthalmology clinical journals fail to provide a Snellen equivalent when visual acuity

202 r, their precise target interaction profiles fail to provide complete mechanistic underpinnings for t

203 ptical, X-ray and photoelectron probes often fail to provide interface-specific information in such s

204 FEN1 also failed to provide excision of the 5'-adenylated BER inte

205 or dry and wet food, respectively), but many failed to provide nutritional minimum (e.g. Cu, 20% of w

206 volving patients of other ethnic backgrounds failed to provide sufficient evidence of an effect of at

207 apamycin did not trigger micro-lipophagy and failed to provide the needed substitute energy source fo

208 nts of controversial receptor localizations, failing to provide support for CRF1 expression in centra

209 Corticosterone failed to re-establish extinguished preference alone but

210 oup, for ASD participants a smaller response failed to reach statistical significance.

211 ted in the circulation of the recipients and failed to reach the endocrine cells of grafted islets.

212 In contrast, cardiomyocytes failed to reactivate the neonatal proliferative network

213 Standard isotropic culture fails to recapitulate the spatiotemporal gradients prese

214 However, failing to recognize the additional role of environmenta

215 cal analyses, but many molecular phylogenies fail to recover this relationship.

216 the early and delayed groups, respectively, failed to recover renal function (absolute difference, -

217 s with sPE, which dedifferentiated in vitro, failed to redecidualize in culture.

218 ve THR-184 through a range of dose exposures failed to reduce the incidence, severity, or duration of

219 cent research suggests that extinction often fails to reduce fear when administered soon after trauma

220 tly interact with an NACbs, and the proteins failed to regulate a promoter lacking a crucial NACbs.

221 impaired H3-H4 tetramerization interactions fail to release from CAF1, indicating that DNA depositio

222 ever, current downstream computational tools fail to reliably determine regulatory region accessibili

223 from a developmentally defective strain that fails to remove Pxr-mediated blockage of development and

224 ment using existing quality measures largely fails to remove the effects of RNA degradation when RNA

225 In the absence of pUL31, CMV fails to reorganize nucleolin and UBF and exhibits a rep

226 SC depletion, E(z) knockdown germ cells also fail to replenish lost GSCs.

227 cyclic promastigotes lacking one SODA allele failed to replicate in macrophages and were severely att

228 As expected, the A6 deletion mutant of VACV failed to replicate in noncomplementing cell lines with

229 o inhibit Sin1 translation, and consequently failed to repress mTORC2 activity and invasion.

230 However, all past models tested failed to reproduce the most salient property of an inte

231 on; while exogenous promoter-reporter assays failed to reproduce the similar outcomes.

232 Although engineered overexpression of EPCR fails to reproduce the effects of UM171 on HSC activity,

233 Unexpectedly, expression of mature HMR failed to rescue not only the plastidial but also the nu

234 Bone marrow transplantation failed to rescue outgrowth.

235 ctive in Ca(2+) binding in either C2A or C2C failed to rescue two defects in PM lipid homeostasis obs

236 malizing APP gene copy number in Ts65Dn mice fails to rescue plasticity.

237 is study, we show that CX3CR1-deficient mice fail to resolve gut inflammation despite high production

238 CD300f-deficient mice failed to resolve dextran sulfate sodium-induced colonic

239 ction, SCD mice continued to deteriorate and failed to resolve the infection, resulting in increased

240 he SHS-exposed Scnn1b-Tg(+) (SHS-Tg(+)) mice failed to resolve these infections.

241 in lung and other cancers, but some patients fail to respond and in those that do resistance inevitab

242 at patients with 11q22.1-q22.2 amplification fail to respond to radiotherapy.

243 notherapy and HSP90 inhibitors.Many patients fail to respond to T cell based immunotherapies.

244 approved for MIBC, the majority of patients fail to respond, suggesting existence of complementary i

245 proportion of patients with many tumor types fail to respond.

246 rsal root ganglion neurons cultured in G-CSF failed to respond to G-CSF in vitro, and Csf3r gene expr

247 C, we demonstrate that tumors expressing ARF failed to respond to treatment with the platinum-based c

248 AnkB variants that fail to restore normal lipid accumulation and GLUT4 loca

249 orrespond to the postimplantation embryo and fail to resume development in chimaeric assays.

250 remains controversial because ROS scavengers fail to retard mitophagy.

251 zymatic liberation only if mechanical forces fail to retrieve antigen.

252 e closest invertebrate relatives of hagfish, failed to reveal evidence of an intact vwf gene.

253 However, in vivo studies have failed to reveal such a function, supporting instead a c

254 nted BTP, whereas nerve block after movement failed to reverse BTP.

255 s transplanted in the peritoneal cavity have failed to reverse diabetes in humans.

256 bind the PP2A-C subunit or activate PP2A and failed to reverse the tumorigenic phenotype induced by P

257 ot enter B-cell follicles, and those that do fail to robustly control viral replication in the TFH po

258 When these neurons are ablated, fish failed to rotate their eyes following either nose-up or

259 bidirectional because Mecp2 KO neurons also failed to scale down mEPSC amplitudes and GluA1 synaptic

260 ) lacked a NAP6-defined extended panel; many failed to screen all cases for chlorhexidine 19/44 (43%)

261 g meiotic resumption, homologous chromosomes failed to segregate accurately during meiosis I.

262 Conclusion COX-2 expression by IHC failed to select patients who could benefit from selecti

263 responsible for effective active treatments failing to separate from placebo.

264 rprisingly, patients with monophasic disease failed to show age-expected changes in diffusion paramet

265 ses of vitamin D supplementation trials have failed to show clear improvements in blood pressure, ins

266 ple integrin antagonist drug candidates have failed to show efficacy in cancer clinical trials.

267 ysis using the per-protocol sample (n = 153) failed to show noninferiority of GSH-I (adjusted effect,

268 es with CRISPR/Cas9-mediated knockout of C3G failed to show repression of histone marks and did not s

269 In contrast, VEGFR1/sVEGFR1 knockout EVs failed to show similar protection, thus indicating that

270 nsive glycemic control (IGC) targeting HbA1c fails to show an unequivocal reduction of macrovascular

271 with Dunn test), while standard gemcitabine failed to significantly reduce tumor growth.

272 dendrites grow into HSPG-deficient areas but fail to stay there.

273 omains from other receptors, EGFR and FGFR1, failed to stimulate TrkB phosphorylation.

274 biosis associated with sensitization to food fails to stimulate protective tolerogenic pathways, lead

275 ons in dopamine signals for reward magnitude failed to subsequently discriminate between reward optio

276 tigation measures, the synergy of strategies fails to substantially lower food prices.

277 fluenza virus infection or vaccination, they failed to support activation of naive CD8(+) T cells.

278 s a consequence, these cytoskeletal networks failed to support cell adhesion at the BTB.

279 Conditioned medium from these cells failed to support CTB invasion.

280 In contrast, additional coactivators failed to support robust HBV replication in the absence

281 g truncation of actin microfilament, thereby failing to support the Sertoli cell morphology and adhes

282 Recombinant FP E244K is monomeric, fails to support bacteriolysis, and binds weakly to C3 p

283 lammasome activation as a TcpB(G158A) mutant failed to suppress pyroptotic cell death and inflammator

284 easing, until the materials in these regions fail to sustain further deformation, leading to voids fo

285 mber when extent is controlled, that infants fail to track extent cues with precision, and that infan

286 teromers in which the ATD of GluA1 is absent fail to translocate, establishing a critical role of the

287 Importantly, while the peptide brHis2 fails to translocate across cell membranes on its own, a

288 ion region were able to persist in ticks but failed to transmit to mice or to establish infection.

289 ular polysaccharide (EPS) locus consistently failed to transmit.

290 nt human cells lack triplet microtubules and fail to undergo centriole maturation.

291 d that most pathogenic TREM2 mutant proteins fail to undergo normal maturation in the Golgi complex a

292 are particularly tolerant to DNA damage and fail to undergo senescence or regulated cell death upon

293 The epimerized hexaketide failed to undergo cyclization and was exclusively hydrol

294 nd defect in lung development with lung buds failing to undergo branching morphogenesis and progressi

295 showing that MEFs lacking AMPK activity also failed to up-regulate IFN-beta and TNF-alpha after treat

296 We found that PRMT1 knock-out macrophages failed to up-regulate PPARgamma expression in response t

297 Tfe3 knockout (Tfe3KO) mice in the fed state failed to upregulate Ppargamma and the adiponectin gene,

298 Mean TICL failed to vary during follow-up (307 +/- 288 mum at 3 mo

299 d more productive environments respectively, failed to vary with delta(15) N.

300 When metabolic processes fail to work properly or effectively, heart muscle dysfu