ライフサイエンスコーパス: fail-safe

1 , no double-lumen tube positioning method is fail-safe.

2 nd angiogenesis and reveal the presence of a fail-safe antiproliferative mechanism.

3 Fail-safe calculations reflecting the number of unpublis

4 aightforward mechanistic explanation for the fail-safe cellular senescence response elicited by acute

5 ity of host/virus interactions and suggest a fail-safe escape mechanism by virus-infected cells for e

6 dal expression of RBP9, providing a maternal fail-safe for dosage compensation.

7 ng assumptions for valid IV analyses are not fail-safe, in that there are situations where the approa

8 e of multiple pathways may be important for "fail-safe" induction and maintenance of cell cycle arres

9 ream open reading frames (uORFs) acting in a fail-safe manner to inhibit the translation from the mai

10 itiator production, RepC/C* could serve as a fail-safe means of preventing autocatalytic replication.

11 autocrine regulation, APCs have an inherent fail-safe mechanism against inappropriate activation and

12 ne-induced senescence (OIS) that serves as a fail-safe mechanism against malignant transformation.

13 be components of an evolutionarily conserved fail-safe mechanism by which animals protect against neo

14 uced, nondeletional tolerance can serve as a fail-safe mechanism by which clones of autoeffector T ce

15 Cleavage at this site is probably part of a fail-safe mechanism by which trypsin, which is activated

16 ing secondary necrosis provides an important fail-safe mechanism counteracting inflammatory responses

17 This appears to be a fail-safe mechanism ensuring that the active sites on th

18 The presence of two triggers may represent a fail-safe mechanism ensuring the timely reset of the rep

19 reinforcing and evolutionarily advantageous fail-safe mechanism for respiratory rhythmogenesis in ma

20 Apoptosis induced by c-Myc is a critical fail-safe mechanism for the cell to protect against unre

21 This robust fail-safe mechanism is eventually bypassed by transforme

22 K kinase activity has a critical role in the fail-safe mechanism of IRES-dependent translation when m

23 ne, initiates a liver-specific translational fail-safe mechanism that deters protein synthesis under

24 not serve as a degron, but rather provide a fail-safe mechanism that expands the range of RQC-degrad

25 usceptible to GCV, representing an effective fail-safe mechanism to abolish viral replication in a cl

26 ur data indicate that miR-196 functions in a fail-safe mechanism to assure the fidelity of expression

27 erization via CD40:CD40L blockade provides a fail-safe mechanism to control alloreactive T cells that

28 athway in mammalian cells serves mainly as a fail-safe mechanism to ensure efficient secretion of sma

29 ing relative to other components serves as a fail-safe mechanism to ensure that septal PG synthesis p

30 -mRNA splicing, and we interpreted this as a fail-safe mechanism to ensure the cotranscriptional recr

31 ative stress response program that acts as a fail-safe mechanism to limit oncogenic transformation an

32 implies that premature senescence acts as a fail-safe mechanism to limit the transforming potential

33 at AID-induced damage at telomeres acts as a fail-safe mechanism to limit the tumor promoting activit

34 kpoint (or spindle assembly checkpoint) is a fail-safe mechanism to prevent chromosome missegregation

35 from natural infection or serve solely as a fail-safe mechanism to prevent overt disease in infected

36 cripts are degraded by NMD, which provides a fail-safe mechanism to remove spurious transcripts that

37 results suggest that Ad12 likely employs a "fail-safe" mechanism to ensure that the transcription of

38 of participation of autocrine TGFbeta in a "fail-safe" mechanism to generate cell death in response

39 These data support the idea of a central "fail-safe" mechanism whereby hypoglycemia can override t

40 studies of PRC1 occupancy also suggested a "fail-safe" mechanism, whereby PRC1/Bmi1 concentrates at

41 Biologically, fail-safe mechanisms identified by the ab initio approac

42 One of these fail-safe mechanisms is mediated by the NRD complex, sim

43 mechanisms to partially bypass the multiple fail-safe mechanisms that protect against cleavage of ge

44 ape from host vacuoles and utilizes multiple fail-safe mechanisms to avoid causing toxicity to infect

45 lay pivotal roles in signaling and represent fail-safe mechanisms to prevent self-nucleic acid recogn

46 The immune system uses fail-safe mechanisms to suppress infection-associated ti

47 nt of safe vectors for gene therapy requires fail-safe mechanisms to terminate therapy or remove gene

48 Thus, pRb loss triggered multiple fail-safe mechanisms whereby urothelial cells evade tumo

49 An extension, called the fail-safe model, envisaged an optimum level of gene dera

50 idity and applicability of the continuum and fail-safe models.

51 Trim and fill analyses and fail-safe n calculations suggest that the results are no

52 ty, T(2)=0.04; I(2)=22.75%; and high classic fail-safe N=240).

53 lication bias in these reports, although the fail-safe numbers were 2,020 and 750 for healthy and dis

54 dback regulators that may have overlapping ("fail-safe") or specific functions.

55 ulates LCRs and Ca transient decay to insure fail-safe pacemaker cell operation within a wide range o

56 urchin embryo reveal a sequence of encoded "fail-safe" regulatory devices.

57 s show that Runx2 and MYC overcome distinct "fail-safe" responses and that their selection as collabo

58 Functionally, both components of this fail-safe silencing mechanism are required to prevent ec

59 gulated by multiple pre- and post-activation fail-safe steps.

60 activation of p53 and JNK may constitute a "fail-safe" switch for the JNK-dependent apoptotic respon

61 This may represent a fail-safe system that protects the host against genetic

62 d citrulline recycling via Ass1 and Asl is a fail-safe system that sustains optimum NO production.

63 RFs and the three proteins formed a multiple fail-safe system that tightly inhibits the translation o

64 hese coordinated signaling pathways ensure a fail-safe system to prepare the oocyte for fertilization

65 his bimodal control mechanism may comprise a fail-safe system, such that transcription of the ftsQA g

66 This feed forward "fail safe" system, kept in check by a high basal phospho

67 Both fail-safe termination mechanisms trigger degradation of

68 hairpin-dependent termination, one or more "fail-safe" termination mechanisms may exist in the cell.

69 h the +93 site quantitatively terminate at a fail-safe terminator located further downstream at +250.

70 Such a mechanism provides a "fail-safe" that prevents neurons from dying by accidenta

71 ation of short noncoding RNA genes and for a fail-safe transcriptional termination mechanism of prote

72 ggered on viral amplicons further guaranteed fail-safe virus detection.