ライフサイエンスコーパス: failed to induce

1 Finally, AbetaOs failed to induce depressive-like behavior in Toll-like recept

2 C/EBPalpha mutants that mimic acetylation failed to induce granulocytic differentiation in C/EBPalpha-d

3 ium nucleatum clinical isolates with FadA and Fap2 adhesins failed to induce inflammation and tumorigenesis, pks(+)Escher

4 Adiponectin and AdipoRon failed to induce facilitation of fear extinction and elicit i

5 It also failed to induce reinstatement of drug-seeking behavior.

6 sites (K242, 259, 290 and 569R) abolished JNK1 binding and failed to induce apoptosis.

7 entry in ECs via TRPM2 as compared with wild-type PMNs and failed to induce PMN transmigration.

8 patitis patients had high expression of SIRT1 and SIRT7 and failed to induce p-FOXO3 and apoptosis in response to LPS.

9 out mice continued to exhibit low liver Hamp at 8 weeks and failed to induce Hamp in response to Bmp6 in primary hepatocy

10 Consequently, AVP failed to induce the sustained intracellular Ca(2+) mobilizat

11 CAR3, ectopic expression of the Cas-binding mutant of BCAR3 failed to induce Rac1 activity in breast cancer cells.

12 Bleomycin failed to induce miR-34a in p53- or plasminogen activator inh

13 t that activated solely G proteins, induced chemotaxis, but failed to induce receptor internalization or beta-arrestin 2

14 ve strains attained high levels of mucosal colonization but failed to induce robust vaginal immunopathology (neutrophil r

15 1-fold), and serum intact-FGF23 (1.6-fold) in controls, but failed to induce Fgf23, Nurr1 mRNA, or intact FGF23 productio

16 compromised; pDCs promoted plasmablast differentiation but failed to induce Breg cells.

17 hereas both neutrophils and CD4 T cells presented HMBPP but failed to induce gammadelta T cell expansion in the presence

18 d apoptosis-associated speck-like protein containing a CARD failed to induce HBMEC activation.

19 dly, in WT hosts, donor MHC I-deficient hematopoietic cells failed to induce hyporesponsiveness to activating receptor st

20 ective antigen-specific T-cell responses, and their T cells failed to induce colitis after adoptive transfer to Rag(-/-)

21 Transfer of TNFR2-deficient Teff cells failed to induce full-fledged colitis, unlike WT Teffs.

22 Oral delivery failed to induce RNAi effects and we suggest this is attribut

23 In the SKM-D2KO mice, acute treadmill exercise failed to induce PGC-1a fully in soleus muscle (1.9- vs. 2.8-

24 ific antibody responses in rabbits and macaques, but so far failed to induce broadly neutralizing antibodies.

25 of mutated caveolin-1 in caveolin-1-null mouse fibroblasts failed to induce formation of caveolae due to retention of th

26 ght subvert cell-mediated immunity, we found that C. gattii failed to induce dendritic cell (DC) maturation, leading to d

27 Encapsulated C. gattii failed to induce human monocyte-derived DC maturation and T c

28 However, ns2(H126R) failed to induce RNase L activation in BMM treated with IFNAR

29 Thrombin however failed to induce the spatially extensive response in microves

30 Analysis of these cells revealed that CDK4/6 inhibition failed to induce cell-cycle arrest or senescence.

31 L-4, and conditioned media from IL-4-stimulated macrophages failed to induce expression of thermogenic genes, such as unc

32 By contrast, homogenates from brains of APPSwePSEN1dE9 mice failed to induce seeding and spreading of amyloid-beta pathol

33 mmunoglobulin E responses, and IL-1-receptor-deficient mice failed to induce iBALT formation.

34 Germ-free mice failed to induce IL-36gamma in response to dextran sodium sul

35 eg depletion obtained in BAC transgenic Foxp3.LuciDTR4 mice failed to induce complete rejection of HCmel12 melanomas, dem

36 assays, whereas transcriptionally inactive R175H p53 mutant failed to induce the luciferase expression from this promoter

37 Despite colonizing the murine stomach, ureB mutants failed to induce IL-1beta and IL-18 secretion and to promote

38 P. aeruginosa isolates from CF patients failed to induce inflammasome activation, as measured by the

39 After stimulation, T lymphocytes from patients failed to induce glycolysis, OXPHOS, ATP production, GLUT1 ex

40 also demonstrated that the primary infection with TC-PC177 failed to induce complete cross-protection against challenge

41 xtensive fusion of liposome membranes, while mutant peptide failed to induce any lipid mixing.

42 ngal mutants lacking a functional Fusarium (F)-RALF peptide failed to induce host alkalinization and showed markedly redu

43 n addition, in vivo infection with Streptococcus pneumoniae failed to induce PU.1 expression or upregulate neutrophil eff

44 Microfilarial protein failed to induce inflammation in either TLRKO macrophage or m

45 fficiently and produced IFN-gamma in response to R24L, R24C failed to induce an effective antitumor response.

46 mal transition (EMT) of ovarian cancer cells in vivo, STAT4 failed to induce EMT directly in vitro, suggesting that STAT4

47 However, several studies failed to induce performance deficit implementing this approa

48 Th17 response was absent in immunized IL-23R(-/-) mice that failed to induce protection upon virulent Leishmania challeng

49 oring glutamic acid instead of valine at position 30 (V30E) failed to induce cell death and activation of caspases.

50 neurotropic herpesviruses, infection with unrelated viruses failed to induce this response.