ライフサイエンスコーパス: failed to induce

1 T cells lacking caspase-1 failed to induce colitis or confer protection against C. rode

2 onine (Thr) to alanine (Ala) substitution at amino acid 79, failed to induce these phenotypes, indicating that Thr 79 is

3 ium nucleatum clinical isolates with FadA and Fap2 adhesins failed to induce inflammation and tumorigenesis, pks(+)Escher

4 Adiponectin and AdipoRon failed to induce facilitation of fear extinction and elicit i

5 It also failed to induce reinstatement of drug-seeking behavior.

6 sites (K242, 259, 290 and 569R) abolished JNK1 binding and failed to induce apoptosis.

7 entry in ECs via TRPM2 as compared with wild-type PMNs and failed to induce PMN transmigration.

8 patitis patients had high expression of SIRT1 and SIRT7 and failed to induce p-FOXO3 and apoptosis in response to LPS.

9 out mice continued to exhibit low liver Hamp at 8 weeks and failed to induce Hamp in response to Bmp6 in primary hepatocy

10 F(ab')2-only fragments of anti-CD47 antibodies failed to induce phagocytosis by human macrophages, indicatin

11 The soluble antigens failed to induce IFN-gamma production, whereas inactivated Bp

12 sting for 24 hr, which increased Npy expression in the Arc, failed to induce Npy expression in the VTA.

13 Bleomycin failed to induce miR-34a in p53- or plasminogen activator inh

14 stimulation of VTA or substantia nigra dopamine cell bodies failed to induce food approach or eating.

15 ve strains attained high levels of mucosal colonization but failed to induce robust vaginal immunopathology (neutrophil r

16 ve mutants retained their interaction with both kinases but failed to induce activation, supporting a role for Nef homodi

17 ft inflammation, inhibited antidonor T-cell reactivity, but failed to induce Treg, resulting in mild prolongation of graf

18 potent protumorigenic expansion of Th17 cells in vitro but failed to induce antitumor Th1 differentiation.

19 ells by CD103(+) dendritic cells, exogenous apoptotic cells failed to induce transforming growth factor-beta1 expression

20 ration of supernatants from biopsies of patients with IBS-D failed to induce visceral hypersensitivity or increase the le

21 Oral delivery failed to induce RNAi effects and we suggest this is attribut

22 Unexpectedly, DFO failed to induce EBV reactivation in cell lines that express

23 An ASAP1 construct that lacked the N-BAR domain failed to induce cellular projections.

24 8p, sustained catecholaminergic stimulation almost entirely failed to induce H3S28p.

25 ific antibody responses in rabbits and macaques, but so far failed to induce broadly neutralizing antibodies.

26 of mutated caveolin-1 in caveolin-1-null mouse fibroblasts failed to induce formation of caveolae due to retention of th

27 Thrombin however failed to induce the spatially extensive response in microves

28 Type III IFNs failed to induce IRF1 expression because of low IFNlambda rec

29 allele, which generated stable IgHR but no detectable IgHC, failed to induce PreB development.

30 Conversely, infants failed to induce TNF-alpha after HDM + LPS sensitization.

31 Analysis of these cells revealed that CDK4/6 inhibition failed to induce cell-cycle arrest or senescence.

32 of desensitizing TRPA1, and unlike allyl isothiocyanate, it failed to induce nocifensive behaviors in mice.

33 A mutant lacking the regulatory protein LldR failed to induce lldD transcription in response to l-lactate.

34 L-4, and conditioned media from IL-4-stimulated macrophages failed to induce expression of thermogenic genes, such as unc

35 Expression of Akt3 in p47 (phox-/-) MEFs failed to induce ROS and to inhibit cell proliferation.

36 Microbiota of Itch(-/-) mice failed to induce spontaneous colitis upon transfer to Itch(+/

37 eg depletion obtained in BAC transgenic Foxp3.LuciDTR4 mice failed to induce complete rejection of HCmel12 melanomas, dem

38 Consistently, DKK3, vasorin and neogenin failed to induce dormancy in cells expressing dominant-negati

39 p53-deficient cells, not expressing p21, failed to induce senescence, but were still able to induce a

40 5ASKH-HP parasites failed to induce significant infection even in severely immun

41 mic acid (E) mutant Y138E, which can mimic phosphotyrosine, failed to induce transient DNA replication, although it maint

42 Microfilarial protein failed to induce inflammation in either TLRKO macrophage or m

43 mal transition (EMT) of ovarian cancer cells in vivo, STAT4 failed to induce EMT directly in vitro, suggesting that STAT4

44 Further, beta3-agonist stimulation failed to induce Ucp1-Cre expression in BMAT.

45 We found that this strain failed to induce the nonprotective T helper cell type 2 (Th2)

46 er, adolescent social isolation, an environmental stressor, failed to induce deficits in sociability or sensorimotor gati

47 However, several studies failed to induce performance deficit implementing this approa

48 Th17 response was absent in immunized IL-23R(-/-) mice that failed to induce protection upon virulent Leishmania challeng

49 of 1,952 non-essential genes was screened for mutants that failed to induce IL-10 in myeloid-derived suppressor cells (M

50 B such as tumor necrosis factor alpha (TNF-alpha) and vgRNA failed to induce NF-kappaB-dependent gene expression in infec