ライフサイエンスコーパス: faithful

1 t is vitally important for replication to be faithful.

2 otent stem cells and further demonstrate the faithful alignment of phenotypes in differentiated cells

3 Preclinical studies in faithful and informative mouse models, in concert with k

4 relayed information and ensured its robust, faithful and more persistent representation.

5 se findings suggest that B35DNAP may perform faithful and processive genome replication in vivo and,

6 ilable tissue for study and by the lack of a faithful animal model.

7 umour suppressor genes and the generation of faithful animal models of human cancer.

8 of available IHCC cell lines or genetically faithful animal models.

9 mer based on the clade A BG505 sequence is a faithful antigenic and structural mimic of the native tr

10 However, retaining faithful antigenic presentation while removing toxin vir

11 The preprophase band (PPB) is a faithful but transient predictor of the division plane i

12 Faithful cell cycle progression in the dimorphic bacteri

13 in turnover of several factors critical for faithful cell cycle progression.

14 r chromatids during anaphase is critical for faithful cell division.

15 n of the TF network by Cdk1 is necessary for faithful cell division.

16 nable chromosome segregation and orchestrate faithful cell division.

17 We demonstrate that faithful CENP-A deposition requires integrated signals f

18 The fundamental requirement for faithful centromere inheritance is the controlled deposi

19 aeruginosa, both SMC and MksB contribute to faithful chromosome partitioning, with their inactivatio

20 s of Cse4 in regulating Cse4 proteolysis for faithful chromosome segregation and a role for Doa1 in u

21 sotropic and rigid form they need to undergo faithful chromosome segregation and division in a crowde

22 ells usually adopt a rounded shape to ensure faithful chromosome segregation and to promote morphogen

23 y for stalled fork recovery, contributing to faithful chromosome segregation and tumor suppression.

24 er division plane positioning is crucial for faithful chromosome segregation but also influences cell

25 aling system, the mitotic checkpoint ensures faithful chromosome segregation by delaying anaphase ons

26 Faithful chromosome segregation depends on the precise t

27 res to bind spindle microtubules and promote faithful chromosome segregation during cell division.

28 kage between homologs, which is critical for faithful chromosome segregation during meiosis I.

29 parental homologous chromosomes, and ensures faithful chromosome segregation during meiosis in sexual

30 n sister chromatids is fundamental to ensure faithful chromosome segregation during mitosis and accur

31 Faithful chromosome segregation entails long-range chrom

32 Faithful chromosome segregation in all eukaryotes relies

33 The kinetochore drives faithful chromosome segregation in all eukaryotes, yet t

34 Mitotic SUMOylation has an essential role in faithful chromosome segregation in eukaryotes, although

35 s, an important safeguard mechanism ensuring faithful chromosome segregation in eukaryotic cells.

36 Faithful chromosome segregation in meiosis is crucial to

37 Faithful chromosome segregation in meiosis requires cros

38 g that Mad2 has a conserved role in ensuring faithful chromosome segregation in meiosis.

39 f Aurora B at the inner centromere to ensure faithful chromosome segregation in metazoans.

40 somal cohesin complex, is a prerequisite for faithful chromosome segregation in mitosis.

41 exerts post-fertilization control to ensure faithful chromosome segregation in the embryo.

42 iscrete structures-processes fundamental for faithful chromosome segregation into daughter cells.

43 Faithful chromosome segregation is accomplished by attac

44 Faithful chromosome segregation is required for cell and

45 ase Aurora B as a catalytic subunit, ensures faithful chromosome segregation through destabilizing in

46 Faithful chromosome segregation with bipolar spindle for

47 ole in many biological processes: it ensures faithful chromosome segregation, regulates gene expressi

48 n ATR pathway acts at centromeres to promote faithful chromosome segregation, revealing functions of

49 Genome stability depends on faithful chromosome segregation, which relies on mainten

50 s to correct improper attachments and ensure faithful chromosome segregation.

51 ial to link homologous chromosomes and drive faithful chromosome segregation.

52 s Cse4 from Psh1-mediated ubiquitination for faithful chromosome segregation.

53 y, and its mechanical disruption compromised faithful chromosome segregation.

54 ensures high levels of cohesin and promotes faithful chromosome segregation.

55 rotubule depolymerase activity essential for faithful chromosome segregation.

56 to trigger DNA-repair synthesis that ensures faithful chromosome segregation.

57 l to ensure progression through anaphase and faithful chromosome segregation.

58 ers kinetochores to facilitate efficient and faithful chromosome segregation.

59 ase to ensure efficient error correction and faithful chromosome segregation.

60 ation imposed by Ipl1 kinase is critical for faithful chromosome segregation.

61 tochores to promote biorientation and ensure faithful chromosome segregation.

62 l2 links many of the processes essential for faithful chromosome segregation.

63 e4 phosphorylation and its role in promoting faithful chromosome segregation.

64 es the spindle assembly checkpoint to ensure faithful chromosome segregation.

65 le-kinetochore interface during anaphase for faithful chromosome segregation.

66 9, the establishment of heterochromatin, and faithful chromosome segregation.

67 e kinetochore complex, which is required for faithful chromosome segregation.

68 dk1 destabilizes k-MT attachments to promote faithful chromosome segregation.

69 d mitotic chromosome organization to support faithful chromosome segregation.

70 gulating removal of centromeric cohesins and faithful chromosome segregation.

71 hment of sister chromatid cohesion to ensure faithful chromosome segregation.

72 of the kinetochore and is required to ensure faithful chromosome segregation.

73 oisomerase II (TOP2) plays a pivotal role in faithful chromosome separation through its strand-passag

74 osome in maintaining centromere function and faithful chromosomes segregation.

75 on, provides a molecular memory that ensures faithful commitment to transcriptional programs during m

76 iate level of active RHOA at the midbody for faithful completion of cytokinesis and genome inheritanc

77 able quantum technologies may be achieved by faithful conversion between matter qubits and photonic q

78 Faithful copying of the genome is essential for life.

79 olume of interest targeted at the SN provide faithful correlates of nigral neuronal counts across a f

80 This faithful CRC model provides genetic evidence that Kras(m

81 themes and trends, ensuring maximal fit and faithful data representation.

82 romeres, bind spindle microtubules to ensure faithful delivery of chromosomes during cell division.

83 These trans-acting factors enable the faithful delivery of seven Sm proteins onto snRNA and th

84 be studied in native-like media to achieve a faithful description of their function.

85 transcriptional perturbations and allows for faithful detection of both baseline transcriptional prof

86 noise to the detected signal and demonstrate faithful detection of pico-second single photons.

87 Here we show that ptk7 mutant zebrafish, a faithful developmental model of IS, exhibit defects in e

88 TCF4 served as a faithful diagnostic marker of BPDCN, and its downregulat

89 ncies in current approaches, leading to more faithful differentiation strategies as well as providing

90 odies (SPBs) in fungi, are important for the faithful distribution of chromosomes between daughter ce

91 together with the mitotic spindle ensure the faithful distribution of chromosomes between daughter ce

92 Faithful DNA repair is essential to maintain genome inte

93 HR is a faithful DNA repair pathway and has been largely charact

94 ecific activation of AID and a perversion of faithful DNA repair towards error-prone outcomes.

95 lation of RNA processing is needed to ensure faithful DNA replication and repair.

96 counteracts replication stress and promotes faithful DNA replication consists of the Fanconi anemia

97 Faithful DNA replication is a cornerstone of genomic int

98 Faithful DNA replication is essential for genome stabili

99 Faithful DNA replication is essential for normal cell di

100 nome stability underscores the importance of faithful DNA replication.

101 on plane positioning is essential to achieve faithful DNA segregation and to control daughter cell si

102 B35DNAP is a highly faithful DNAP that can couple strand displacement to pro

103 ear antigen (PCNA) lies at the center of the faithful duplication of eukaryotic genomes.

104 Faithful duplication of the genome in S phase followed b

105 The recombinant RET2 catalyzes a faithful editing on gapped (precleaved) double-stranded

106 rgely independent facets of temporal coding: faithful entrainment of interspike intervals to the stim

107 esponsible for genome replication are highly faithful enzymes that nonetheless cannot deal with damag

108 g the Poisson-Boltzmann equation, leading to faithful estimates of the rate constants.

109 per 10(6)-10(8) incorporations) and support faithful eukaryotic genome replication.

110 Faithful execution of developmental programs relies on t

111 A faithful execution of these steps defines the ultimate p

112 these insights to inform the development of faithful experimental models to test the efficacy of new

113 Our work establishes a robust and faithful experimental system of the early events of epig

114 of eGFP-labeled hippocampal cells confirmed faithful expression of eGFP within GHSR-containing, ghre

115 ce through VELOCIGENE technology resulted in faithful expression of human CSF-1 in these mice both qu

116 The faithful expression of the fluorescent reporter in ProxT

117 nic and 5' knirps (kni) enhancers produces a faithful expression pattern, even though the intronic en

118 n isomorphic nucleoside analogue acting as a faithful fluorescent substitute of G, with respectable q

119 utation in the early coding region, ensuring faithful gene knockout.

120 of DNA before cell division is essential for faithful genetic inheritance.

121 s a logical framework for the development of faithful genetic models and new therapeutic approaches.

122 Faithful genome duplication and inheritance require the

123 that it plays an important role in securing faithful genome duplication.

124 ur understanding of the mechanisms governing faithful genome inheritance.

125 Faithful genome propagation requires coordination betwee

126 Faithful genome transmission during cell division requir

127 phorylation for proper spindle formation and faithful genomic transmission.

128 Overall, we provide a faithful H3.3(K27M)-pHGG model which enables insights in

129 g is an essential meiotic event that ensures faithful haploidization and recombination of the genome.

130 nt studies in Drosophila cells revealed that faithful homologous recombination (HR) repair of heteroc

131 G from Escherichia coli, we demonstrate that faithful images of 2D crystalline and non-crystalline me

132 est that black-browed albatrosses are highly faithful in their foraging habitat but it is rather site

133 , detect very rare phenotypes, and construct faithful in vitro disease models.

134 Most models focused on the faithful in vitro restoration of T cell differentiation

135 to predict residues of the RdRp required for faithful incorporation of nucleotides represents an esse

136 esults show that hemodynamic signals are not faithful indicators of the mean neural activity in the f

137 insidious because neither base in it carries faithful information to direct the repair of the other.

138 The spindle assembly checkpoint ensures the faithful inheritance of chromosomes by arresting mitotic

139 se detrimental effects, thereby ensuring the faithful inheritance of G4-containing genomes.

140 In mammals, faithful inheritance of genomic methylation patterns ens

141 highly condensed mitotic chromatin to ensure faithful inheritance of prior accessibility status acros

142 struction at the end of prophase I to ensure faithful inheritance of the genome.

143 subsequent anchorage at its tip ensures the faithful inheritance of this organelle.

144 DNA polymerases facilitate faithful insertion of nucleotides, a central reaction oc

145 arly the C-nucleosidic purine analogues, are faithful isomorphic and isofunctional surrogates of thei

146 Faithful long-term average interaural level differences

147 Experiment 3 maintained faithful long-term average interaural level differences

148 Faithful maintenance and propagation of eukaryotic genom

149 Cell proliferation and survival require the faithful maintenance and propagation of genetic informat

150 bidopsis METHYLTRANSFERASE 1 (MET1) controls faithful maintenance of cytosine methylation at CG sites

151 This was accompanied with a faithful maintenance of DNAme in the breast cancer impla

152 We also obtained faithful marker expression from a tissue-specific promot

153 Technical challenges have limited faithful measurement of TCR diversity after allo-HSCT.

154 Faithful meiotic chromosome segregation and fertility re

155 conserved regulatory mechanisms that ensure faithful meiotic chromosome segregation in diverse speci

156 n homologous chromosomes is required for the faithful meiotic segregation of chromosomes and leads to

157 ganism), there is no gold standard to assess faithful metallocofactor assembly and associated functio

158 nt implications for the use of cell lines as faithful mimics of in vivo epigenetic and physiological

159 onal modification of mitochondrial tRNAs for faithful mitochondrial function.

160 1-mediated mtDNA processing is essential for faithful mitochondrial genome replication and might be r

161 stalks with the actin cytoskeleton to ensure faithful mitosis and spindle positioning is unclear.

162 It preserves centrosome integrity and faithful mitosis during the rapid cleavage division of b

163 pVHL in mediating oriented cell division and faithful mitotic checkpoint function in the renal epithe

164 dings further expand Mps1's significance for faithful mitotic chromosome segregation and emphasize th

165 ously undescribed mechanism for interrupting faithful mitotic progression and may ultimately inform t

166 em to mTOR signaling in a pathway to promote faithful mitotic progression.

167 Using the RCS cell line as a faithful model for proliferating/early prehypertrophic g

168 sh a new genetically and histopathologically faithful model of IHCC and lend experimental support to

169 This study was designed to generate a more faithful model of Parkinson's disease by injecting human

170 enotypes in primates, we must have access to faithful model systems for a wide range of cell types.

171 We validate the Vk*MYC transgenic mouse as a faithful model to predict single-agent drug activity in

172 uggest that stiffening hydrogels may be more faithful models for studying myofibroblast activation th

173 and genetics underlying attempts to generate faithful models frequently leads to poor outcomes.

174 n cancers, which frequently lack alternative faithful models.

175 g, so that all cleaved RNAs are committed to faithful modification.

176 tterns that identify pTalpha expression as a faithful molecular marker of T lineage commitment.

177 ss than quadratic complexity at one end, and faithful multiscale models with quadratic cost at the ot

178 ho can entrain to an external beat have more faithful neural encoding of temporal modulations in spee

179 nal change of motif D leads to efficient and faithful nucleotide addition by bringing Lys-359 into th

180 to the correctness of the bound nucleotide, faithful nucleotide incorporation is achieved.

181 We conclude that tumours tend to have faithful oncogene splicing and a higher incidence of pre

182 gi in regulating spindle formation to ensure faithful organelle inheritance.

183 mmary, we have established and characterized faithful PDX models of DLBCL and demonstrated their usef

184 ce prior work typecasting TAML activators as faithful peroxidase mimics.

185 ued replication of undamaged DNA by the more faithful PolB1.

186 and B-family DNA polymerases which possess a faithful polymerase activity that preferentially incorpo

187 imulations have indicated that efficient and faithful polymerase function requires highly coordinated

188 Here, we take advantage of a faithful primary neuronal model of ALS and FTD to invest

189 nce modulation SICM scheme allows reasonably faithful probe positioning using the resulting ac respon

190 ns unclear how they act in concert to ensure faithful processing of the damage signal.

191 anillin-actin interaction modes promote the faithful progression of cytokinesis.

192 Faithful progression through the cell cycle is crucial t

193 nt of mitotic "bookmarking" by GATA1 for the faithful propagation of cell-type-specific transcription

194 of neurons at each processing stage enables faithful propagation of kinematic representations throug

195 ng cyclic amplification (PMCA), the topic of faithful propagation of prion strain-specific structures

196 sembly of the large ribosomal subunit and in faithful protein production.

197 ex in a manner that contributes to rapid and faithful protein synthesis.

198 unknown pathway through which ROS may impact faithful protein synthesis.

199 e SRP-cargo interaction drives efficient and faithful protein targeting.

200 The folding probe strategy and the faithful quantification of a particular protein's functi

201 nts and simulations and that finally allow a faithful quantification of the magnetic force for the lo

202 Yet, faithful recapitulation of all AD features in widely use

203 This faithful recapitulation of tissue-specific fate post-tra

204 data transmission and storage, we obtained a faithful reconstruction of the 3D volumetric information

205 chromosome (nucleoid) conformation dictates faithful regulation of gene transcription.

206 ted with the spliceosome, thus requiring its faithful regulation.

207 The faithful relay and timely expression of genetic informat

208 Genetically engineered mouse models provide faithful renditions of events in tumor progression, angi

209 The difference between faithful repair and wreaking mutagenic havoc on the geno

210 Faithful repair of DNA double-strand breaks by homologou

211 Faithful repair of DNA lesions is a crucial task that di

212 curs predominantly during G1 phase, inducing faithful repair, mutagenic processing, and class switchi

213 ression and membrane biogenesis can ensure a faithful replication and adaptation of T. gondii in disp

214 ntial for bacterial cells to co-ordinate the faithful replication and segregation of their genetic ma

215 DNA damage occurs continuously, and faithful replication and transcription are essential for

216 aintaining cellular dTTP pools to ensure the faithful replication of both mitochondrial and nuclear D

217 Efficient and faithful replication of telomeric DNA is critical for ma

218 e accuracy of such a model is validated by a faithful replication of the experimental cryo-EM map com

219 ys that ensure the repair of damaged DNA and faithful replication of the genome.

220 ired for efficient checkpoint activation and faithful replication restart.

221 ure for the genetic linkage groups and allow faithful replication, transcription and transmission of

222 cular sugar, or "sweetness," is not always a faithful reporter of its nutritional value, and recent e

223 Faithful reporting of temporal patterns of intracellular

224 To ensure a faithful representation of cellular metabolism after cel

225 nto a desynchronized state that enables more faithful representation of subtle sensory stimuli.

226 ned for full-membrane models, indicating the faithful representation of the membrane surface by the m

227 d superficial muscles and thus can provide a faithful representation of the neural drive sent to a mu

228 olute density measurements, and consequently faithful representations of molecule counts and position

229 mes), and fungal growth on fruits with their faithful reproductions on the nanofiber mats is illustra

230 lencing, ensuring that only cells undergoing faithful reprogramming initiate XCR.

231 Faithful resetting of the epigenetic memory of a somatic

232 of the role played by p300 in promoting the faithful resolution of mitotic figures as well as proper

233 quantities of infected brain and demonstrate faithful retention of biological and biochemical strain

234 As clinically-faithful rodent models of sporadic PA are currently unde

235 ntrol mitochondrial movement to ensure their faithful segregation during division.

236 between homologous chromosomes ensure their faithful segregation during meiosis.

237 feature of sexual reproduction that ensures faithful segregation of chromosomes and redistributes ge

238 rect chromosome architecture is required for faithful segregation of chromosomes at anaphase I and II

239 Faithful segregation of chromosomes during cell division

240 Faithful segregation of chromosomes to two daughter cell

241 A certain level of this is required for the faithful segregation of chromosomes, but the majority of

242 e is the structural unit responsible for the faithful segregation of chromosomes.

243 The mitotic spindle ensures the faithful segregation of chromosomes.

244 y coordinated events that ultimately lead to faithful segregation of chromosomes.

245 crotubule-based mitotic spindle mediates the faithful segregation of duplicated chromosomes into daug

246 The faithful segregation of duplicated genetic material into

247 Faithful segregation of homologous chromosomes during me

248 I plasmid partitioning systems, facilitating faithful segregation of low copy-number plasmids during

249 once per generation must be coordinated with faithful segregation of newly replicated chromosomes and

250 re-microtubule attachments are essential for faithful segregation of sister chromatids during mitosis

251 threaten to prevent complete replication and faithful segregation of sister chromatids.

252 pindle assembly checkpoint (SAC) ensures the faithful segregation of the genome during mitosis by ens

253 chromosomes during spermatogenesis to ensure faithful segregation post-fertilization.

254 Chromosome alignment fosters faithful segregation through the formation of bi-oriente

255 2) and ParB-like (omega2) proteins to ensure faithful segregation.

256 The faithful self-propagation of this fold involves a divers

257 A prerequisite for faithful signal transmission is the positioning and clus

258 blish that sleep deprivation compromises the faithful signaling of, and the "embodied" reciprocity be

259 insertion to its homologous chromosome in a faithful, site-specific manner.

260 redistributes to the spindle pole to ensure faithful spindle architecture.

261 It also aids faithful splicing of pre-mRNAs containing large introns,

262 enic for the recombinant BAC appears to be a faithful surrogate for TSLP expression, particularly in

263 The faithful targeting of the chimera depends on the express

264 ve rise to distinct prion strains capable of faithful template-driven propagation.

265 d within the neural code, and supplying more faithful templates to the brain mechanisms subserving ph

266 er this kinase might be suitable to maintain faithful timing and execution of anaphase in the absence

267 ithin a single year, females which were more faithful to a specific location had higher reproductive

268 o, convey that they are sharers of knowledge faithful to science's way of knowing and respectful of t

269 tency in the interpretation whilst remaining faithful to the construct under study.

270 ray diffraction shows Mn-SLO is structurally faithful to the native enzyme.

271 show that the resulting implementation stays faithful to the original coding goals while using inhibi

272 ple, yet still tractable, model that remains faithful to the underlying system based on the known lit

273 , increasing numbers of bumblebees stay more faithful to these flowers, even if they become a subopti

274 subpopulations, the probability of remaining faithful to wet season areas ranged between 0.82 and 1.0

275 the accelerated kinetics that allow for the faithful tracking of action potentials in neurons.

276 s at promoters are thought to be crucial for faithful transcriptional regulation.

277 Aminoacyl-tRNA synthetases (aaRSs) ensure faithful translation of mRNA into protein by coupling an

278 Faithful translation of mRNA into the corresponding poly

279 a superfamily of enzymes responsible for the faithful translation of the genetic code and have lately

280 tic information from DNA to protein requires faithful translation.

281 he nucleus, where mitosis and meiosis ensure faithful transmission of chromosomes, the mechanisms of

282 observational learning can give rise to the faithful transmission of cultural adaptations.

283 The faithful transmission of DNA methylation patterns throug

284 ity is crucial for cellular survival and the faithful transmission of genetic information.

285 ases after DNA replication, which results in faithful transmission of methylation patterns during cel

286 Faithful transmission of quantum information is a crucia

287 The sense of hearing depends on the faithful transmission of sound information from the ear

288 Faithful transmission of the genetic information is esse

289 e epigenetic elements that were required for faithful transmission to the daughter cell to accurately

290 genetic information accurately to ensure its faithful transmission.

291 ns is impeded by the limited availability of faithful transmitochondrial animal models.

292 We recently showed that a faithful treatment of such nanoscale interfaces requires

293 hich are often a result of screening in less faithful two-dimensional models.

294 mer resolution site) system is essential for faithful vertical genetic transmission, ensuring the res

295 TMRs is a conserved mechanism, which ensures faithful virus genome maintenance in host cells during c

296 tomography and (68)Ga-NODAGA-RGD PET enabled faithful visualization of PDAC.

297 leotides but also causes the enzyme to favor faithful Watson-Crick base pairing over mutagenic config

298 ale, as this provides a means to distinguish faithful Watson-Crick base-paired DNA from damaged DNA.

299 ns track naturalistic speech in a remarkably faithful way.

300 Transcription patterns were surprisingly faithful within a taxon regardless of treatment, suggest