ライフサイエンスコーパス: fallopian tube

1 ainly located in the upper tract (uterus and fallopian tubes).

2 ectopic pregnancy is embryo retention in the fallopian tube.

3 ht to originate in the distal portion of the fallopian tube.

4 s such as the respiratory epithelium and the fallopian tube.

5 g the testes, epididymis, uterus, ovary, and fallopian tube.

6 t was also present on time epithelium of the fallopian tube.

7 receptor (FSHR) expression in the ovary and fallopian tube.

8 lls but not from the proximal portion of the fallopian tube.

9 and in the general population arise from the fallopian tube.

10 death and sloughing of ciliated cells of the Fallopian tube.

11 the ovary, namely the secretory cells of the fallopian tube.

12 tasis in an ex vivo infection model of human fallopian tubes.

13 e revealing the influence of estrogen on the fallopian tubes.

14 0 and are also predisposed to cancers of the fallopian tubes.

15 od, lymph nodes, vagina, cervix, uterus, and fallopian tubes.

16 mullerian duct-derived epithelium of normal fallopian tubes.

17 salpingography to depict normal and diseased fallopian tubes.

18 s in the toxicity of N. gonorrhoeae to human fallopian tubes.

19 tudy patients with surgically proved dilated fallopian tubes.

20 the lower genital tract into the uterus and fallopian tubes.

21 epithelia in brain ventricles, airways, and Fallopian tubes.

22 production and ciliated cell death in human fallopian tubes.

23 be caused by pelvic adhesions affecting the fallopian tubes.

24 essed by normal endocervix, endometrium, and fallopian tube (60, 64, and 29% of specimens, respective

25 mon biologic origin, likely to be the distal fallopian tube among all cases.High-grade serous carcino

26 nce of blood in a dilated retort-shaped left fallopian tube and a normal right uterus.

27 to 40 years of age, had at least one patent fallopian tube and a normal uterine cavity, and had a ma

28 ealed highest expression of this molecule in fallopian tube and cervical tissues, followed by endomet

29 raepithelial carcinoma in the fimbria of the fallopian tube and involves the ovary secondarily.

30 rovide a novel therapeutic strategy to treat fallopian tube and ovarian HGSC.

31 al role in the initiation and progression of fallopian tube and ovarian HGSC.

32 f open chromatin and histone modification in fallopian tube and ovarian surface epithelial cells (FTS

33 lt malignancies were discovered, four in the fallopian tube and three in the ovaries.

34 velop from intraepithelial carcinomas in the fallopian tube and, as a result, disseminate as carcinom

35 sets to gene expression sets of eight normal fallopian tubes and 499 high-grade serous malignant ovar

36 MR imaging can depict most dilated fallopian tubes and differentiate them from other adnexa

37 ith highest expression in the upper tissues (fallopian tubes and endometrium), followed by cervix and

38 water produced good images of the simulated fallopian tubes and free spill.

39 is commonly result in ascending infection to fallopian tubes and subsequent immune-mediated tubal pat

40 ing genital infections cause inflammation of fallopian tubes and subsequent scarring and occlusion.

41 are relatively common in women with ovarian, fallopian tube, and peritoneal carcinoma (OC) causing a

42 women are for cancers of the breast, ovary, fallopian tube, and peritoneum.

43 st and BRCA-associated gynecologic (ovarian, fallopian tube, and primary peritoneal) cancer.

44 A phantom simulating the uterus, fallopian tubes, and surrounding pelvic cavity was const

45 denocarcinomas originating from the ovaries, fallopian tubes, and the peritoneum.

46 Intraepithelial carcinomas of the fallopian tube are putative precursors to high-grade ser

47 In this review, evidence supporting the fallopian tube as the origin of ovarian cancer is presen

48 taining the relevant cell types of the human fallopian tube as well as a luminal architecture that cl

49 op high-grade serous cancers, removal of the fallopian tube at an early age prevents cancer formation

50 To address the need for a fallopian tube-based model of HGSOC, we have developed a

51 serous peritoneal carcinoma arising from the fallopian tube before it spreads.

52 Adhesion molecules were identified in fallopian tube biopsy specimens cultured with 5 x 10(6)

53 and BRCA2 carriers after RRBSO with ovarian, fallopian tube, breast, and peritoneal cancer published

54 factors for PID, confirmed PID, and occluded fallopian tubes but not with acute C. trachomatis infect

55 by normal vagina and ectocervix and inflamed fallopian tube, but variably expressed by normal endocer

56 women at high risk of ovarian cancer (OC) or fallopian tube cancer (FTC).

57 ve recurrent ovarian, primary peritoneal, or fallopian tube cancer (ROC).

58 cinoma of the peritoneum (four patients), or fallopian tube cancer (two patients) who previously had

59 V epithelial ovarian, primary peritoneal, or fallopian tube cancer and were not selected for EGFR exp

60 ients with recurrent ovarian, peritoneal, or fallopian tube cancer have limited therapeutic options.

61 e epithelial ovarian, primary peritoneal, or fallopian tube cancer, and a clinical complete response

62 ients with recurrent ovarian, peritoneal, or fallopian tube cancer.

63 recurrent EOC, peritoneal serous cancer, or fallopian tube cancer.

64 ioid cancer, including primary peritoneal or fallopian tube cancer.

65 tage IIIC/IV ovarian, primary peritoneal, or fallopian tube cancer.

66 l resemblance to human serous cancers, these fallopian tube cancers highly express genes that are kno

67 It has been proposed that fallopian tube cancers may be precursors of HGSOC but ev

68 II trial included the following: ovarian and fallopian tube cancers or primary carcinoma of the perit

69 -one breast, ovarian, primary peritoneal, or fallopian tube cancers were detected after receipt of ge

70 0 (16%) had peritoneal cancer, four (6%) had fallopian tube cancers, and three (5%) had uterine papil

71 ian cancer, including primary peritoneal and fallopian tube cancers.

72 and recurrent somatic mutations in sporadic fallopian tube cancers.

73 Fallopian tube carcinoma (FTC) is a rare, poorly studied

74 tations among Ashkenazi Jewish patients with fallopian tube carcinoma (FTC) or primary peritoneal car

75 s isolated from a previous transgenic murine fallopian tube carcinoma model, and confirmed that loss

76 t epithelial ovarian, primary peritoneal, or fallopian tube carcinoma with a maximum of two prior che

77 endometrioid ovarian, primary peritoneal, or fallopian tube carcinoma, had received at least two prev

78 d for all women with ovarian, peritoneal, or fallopian tube carcinoma, regardless of age or family hi

79 m women with primary ovarian, peritoneal, or fallopian tube carcinoma.

80 ed from UW, there was a higher proportion of fallopian tube carcinomas (13.3% vs 5.7%; P < .001); sta

81 the level of genomic aberration observed in fallopian tube carcinomas compared with high-grade serou

82 a genome-wide copy number analysis of occult fallopian tube carcinomas identified through risk-reduci

83 ubal intraepithelial carcinomas (STICs), and fallopian tube carcinomas), ovarian cancers, and metasta

84 ade that primary ovarian epithelial tumours, fallopian tube carcinomas, and primary peritoneal carcin

85 ertussis and has been shown to kill ciliated fallopian tube cells in organ culture.

86 tudies examining the transformation of human fallopian tube cells.

87 for temporal resolution, spatial resolution, fallopian tube conspicuity, and free spill conspicuity.

88 However, the molecular pathogenesis of fallopian tube-derived serous carcinomas is poorly under

89 biology, as well as for developing models of fallopian tube disease, such as cancer.

90 e compared with surgical findings of dilated fallopian tube, endometriosis, and salpingitis.

91 s end, the adhesion molecules induced on the fallopian tube endothelium during infection with C. trac

92 and is also expressed in ovarian surface and fallopian tube epithelia.

93 g were investigated by using cultured bovine fallopian tube epithelial (BFTE) cells inoculated with C

94 ctive oocyst) in a primary culture of bovine fallopian tube epithelial (BFTE) cells.

95 SEC) cultures are useful for studying normal fallopian tube epithelial biology, as well as for develo

96 ntify novel and specific biomarkers of early fallopian tube epithelial cell transformation.

97 talized ovarian surface epithelial cells and fallopian tube epithelial cells via a single-run mass sp

98 In the current study, primary human fallopian tube epithelial cells were infected with N. go

99 The fallopian tube epithelium (FTE) has been recognized as a

100 The fallopian tube epithelium (FTE) is one of the progenitor

101 an surface epithelium (n = 31; P = 0.039) or fallopian tube epithelium (n = 28; P < 0.001).

102 op new and robust model systems to study the fallopian tube epithelium as the cell of origin of "ovar

103 experimental model systems for studying the fallopian tube epithelium in high-risk women as well as

104 ad molecular profiles more similar to normal fallopian tube epithelium than ovarian surface epitheliu

105 Ovarian surface epithelium and fallopian tube epithelium, not previously recognized to

106 inomas involving the ovary likely arise from fallopian tube epithelium.

107 iosis on the ciliary beat frequency of human fallopian tube epithelium.

108 isseria gonorrhoeae trafficking across human fallopian tube epithelium.

109 erleukin-8 (IL-8) secretion in primary human fallopian tube explants.

110 difference in ciliary beat frequency between fallopian tubes exposed to peritoneal fluids of women wi

111 ions of genital chlamydial infection include fallopian tube fibrosis and tubal factor infertility.

112 his article, we discuss the emergence of the fallopian tube fimbria as a field of origin for high-gra

113 %) of 147 women with PID and from ovaries or fallopian tubes from 5 (22.7%) of 22 women with PID, but

114 Fallopian tubes from hysterectomy specimens were collect

115 ous ovarian carcinomas (SOCs) arise from the fallopian tube (FT) epithelium rather than the ovarian s

116 Fallopian tube (FT) from women with EP exhibit altered e

117 In EP, embryo retention within the Fallopian tube (FT) is thought to be due to impaired smo

118 om multiple extra-ovarian origins, including fallopian tube, gastrointestinal tract, cervix and endom

119 26 patients with nonuniform sampling of the fallopian tubes (group 1) and 19 patients with complete

120 Brain, placenta and fallopian tube had the highest PI-TP RNA expression.

121 The fallopian tube has been proposed instead as the primary

122 mors of the ovary and Walthard cell nests of Fallopian tubes have been considered to represent urothe

123 primary samples of normal, nondiseased human fallopian tubes, (ii) transformation of FTSECs with defi

124 ome of the fimbrial and proximal ends of the fallopian tube in BRCA1/2 mutation carriers and non-carr

125 high-grade serous carcinomas arise from the fallopian tube in mice.

126 blinded readers correctly identified dilated fallopian tubes in 31 of 41 study patients and correctly

127 ells, and on cells that line the trachea and fallopian tubes in mammals.

128 s in accordance with known cyclic changes of fallopian tubes in response to ovarian hormones and may

129 vagina, ectocervix, endocervix, uterus, and fallopian tubes in the female reproductive tract.

130 invasive epithelial cancers of the ovary or fallopian tube (index cancers).

131 rly identical findings were found in macaque fallopian tubes infected in situ repeatedly with C. trac

132 The fallopian tube is now generally considered the dominant

133 ated by salpingectomy, in which the affected Fallopian tube is removed, or salpingotomy, in which the

134 for finding an extraovarian mass, since the fallopian tube is the most common location for ectopic p

135 ber analyses of laser capture microdissected fallopian tube lesions (p53 signatures, serous tubal int

136 e show that PRKCI is also expressed in early fallopian tube lesions, called serous tubal intraepithel

137 Epithelial shedding and scarring of fallopian tube mucosa are the main consequences of sexua

138 y-stage ovarian neoplasm and one early-stage fallopian tube neoplasm were found.

139 Main outcome measures were nonovarian, non-fallopian tube, nonbreast, positive intra-abdominal peri

140 Patency of fallopian tubes not visualized at hysterosalpingography

141 atory response leads to chronic scarring and Fallopian tube obstruction.

142 hlamydial upper genital tract infection, the fallopian tubes of 40 female Macaca nemestrina were inoc

143 ual cycle, and were best coregistered to the fallopian tubes on contrast-enhanced CT.

144 s a possible origin of HGSOC either from the fallopian tube or from the ovarian surface epithelium.

145 st and BRCA-associated gynecologic (ovarian, fallopian tube or primary peritoneal) cancer when BRCA2

146 ed each adnexa for the presence of a dilated fallopian tube or thickened tubal wall and mucosal folds

147 ith an 80% reduction in the risk of ovarian, fallopian tube, or peritoneal cancer in BRCA1 or BRCA2 c

148 o estimate the reduction in risk of ovarian, fallopian tube, or peritoneal cancer in women with a BRC

149 observed until either diagnosis of ovarian, fallopian tube, or peritoneal cancer, death, or date of

150 ld have confirmation of an invasive ovarian, fallopian tube, or peritoneal cancer.

151 logy and Obstetrics stage IIB to IV ovarian, fallopian tube, or peritoneal epithelial carcinoma.

152 ly confirmed epithelial cancer of the ovary, fallopian tube, or peritoneum (any stage, grade 2 to 3 i

153 on after a diagnosis of cancer of the ovary, fallopian tube, or peritoneum (N = 404).

154 with platinum-resistant epithelial ovarian, fallopian tube, or primary peritoneal cancer received IM

155 atients with suboptimal stage III or IV EOC, fallopian tube, or primary peritoneal cancer were random

156 resistant or -refractory epithelial ovarian, fallopian tube, or primary peritoneal cancer were random

157 Patients with recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer were random

158 , high-grade serous or endometrioid ovarian, fallopian tube, or primary peritoneal cancer, or those w

159 ry or -resistant epithelial ovarian, primary fallopian tube, or primary peritoneal cancer.

160 ential sites: the surfaces of the ovary, the fallopian tube, or the mesothelium-lined peritoneal cavi

161 increase in toxicity of the strain to human fallopian tube organ cultures (HFTOC).

162 In the human fallopian tube organ-culture model, Opa-producing varian

163 ge prevents cancer formation--confirming the fallopian tube origin of the cancer.

164 matory disease (PID) and surgical specimens (fallopian tubes, ovaries, or both) from 22 women with PI

165 e the endometrial and uterine morphology and fallopian tube patency.

166 populations: Primary (cells in the ovary or fallopian tube), Peritoneal (viable cells in peritoneal

167 al and serial sectioning of both ovaries and fallopian tubes, peritoneal and omental biopsies, and co

168 HGSCs frequently arise in the distal fallopian tubes rather than the ovary, developing from s

169 uring hysterosalpingography (0.04-0.55 cGy), fallopian tube recanalization (0.2-2.75 cGy), computed t

170 Five patients underwent simultaneous fallopian tube recanalization.

171 Secretions by epithelial cells of the fallopian tube regulate ovulation through conserved path

172 of eight (25%) animals tested positive from fallopian tube samples.

173 female infertility due to infection-induced Fallopian tube scarring.

174 on acts to drive malignant transformation in fallopian tube secretory cells that are the site of orig

175 Primary human fallopian tube secretory epithelial cell (FTSEC) culture

176 e have developed a system for studying human fallopian tube secretory epithelial cell (FTSEC) transfo

177 With the rise of the fallopian tube secretory epithelial cell as a cell of or

178 The recent identification of the fallopian tube secretory epithelial cells (FTSECs) as th

179 rade serous carcinoma (HGSC) originates from fallopian tube secretory epithelial cells (FTSECs).

180 h factors for GAB2-induced transformation of fallopian tube secretory epithelial cells and clonogenic

181 In primary human fallopian tube secretory epithelial cells, cyclin E1 exp

182 potently transforms immortalized ovarian and fallopian tube secretory epithelial cells.

183 The distal fallopian tube seems to be the dominant site of origin f

184 ylation levels between fimbrial and proximal fallopian tube segments are threefold higher in BRCA mut

185 erous carcinoma, which often arises from the fallopian tubes, showed a weaker genetic correlation wit

186 In positive endocervix, endometrium, and fallopian tube specimens, HD-5 was located in apically o

187 is and identified bacterial 16S sequences in Fallopian-tube specimens from 11 (24%) of 45 consecutive

188 omas are first observed in the stroma of the fallopian tube, suggesting that these epithelial cancers

189 ic aberrations that transform ovarian and/or fallopian tube surface epithelial cells, allowing for th

190 an origin arise in the fimbriated end of the fallopian tube, this site cannot account for all of thes

191 ockets generated by transplanting autologous Fallopian tube tissue subcutaneously.

192 describes the isolation of FTSECs from human fallopian tube tissue, conditions for primary FTSEC cult

193 tion in inflammation was most obvious in the fallopian tube tissue.

194 gly1 null mutant causes much more damage to fallopian tube tissues than its isogenic wild-type paren

195 overexpressed in inflammatory and cancerous fallopian tube tissues.

196 ese Dicer-Pten double-knockout mice, primary fallopian tube tumors spread to engulf the ovary and the

197 ale breast (six cases), ovary (three cases), fallopian tube (two cases), pancreas (three cases), blad

198 + T cells both longitudinally within the RT (Fallopian tube, uterine endometrium, endocervix, ectocer

199 NA expression of TLRs 1 to 6 was observed in fallopian tubes, uterine endometrium, cervix, and ectoce

200 male reproductive tissues, prostate, testis, fallopian tube, uterus, and placenta, as well as in pros

201 e loops between organ modules for the ovary, fallopian tube, uterus, cervix and liver, with a sustain

202 ns and isolated cell cultures from the human fallopian tube, uterus, cervix, and vaginal mucosa were

203 0.139), site of tumor origin (ovaries versus fallopian tubes versus peritoneum) (P = 0.170), and prim

204 The FSHR expression in the ovary and fallopian tube was confirmed by reverse transcription po

205 The signal intensity of normal fallopian tubes was intermediate on T2-weighted images a

206 to 40 years of age with at least one patent fallopian tube were randomly assigned to ovarian stimula

207 anatomy of the ovary, functional cysts, and fallopian tubes were correlated with findings at histopa