ライフサイエンスコーパス: fasted

1 was eliminated after adjustment for the PCF1-Fasted.

2 113.11, P < 0.001) after being fed than when fasted.

3 d beta5 were lower (P<0.05) for fed than for fasted.

4 ion of hepatic lipid biosynthetic genes when fasted.

5 , pancreas, and kidney, all relative to mice fasted 16 h.

6 Myocardial function was examined in fed or fasted (18-22 h) CD36(-/-) and WT mice.

7 n men and women, and adjustment for the PCF1-Fasted abolished the effect.

8 The fed/fasted activities of adipose tissue lipoprotein lipase w

9 ucagon ratio, and HOMA-insulin resistance in fasted adult DKO pigs and blood glucose and C-peptide ch

10 sphorylation in endothelial cells, overnight-fasted adult male rats received continuous GLP-1 infusio

11 Overnight fasted adult male rats were studied.

12 Overnight fasted adults (n = 61) received intravenous infusions of

13 ions in a nationally representative group of fasted adults in the US population in NHANES samples fro

14 Glucose kinetics were equivalent in 5-h fasted alpha1alpha2(lox/lox) and alpha1alpha2(lox/lox) +

15 Overnight-fasted, anaesthetized Sprague-Dawley rats were used to d

16 e body provide a detailed picture of the fed/fasted and active/sedentary states.

17 p at 11.5 years, with 13 616 (79.9%) who had fasted and did not have diabetes mellitus.

18 by changes in estradiol concentration in the fasted and fed conditions.

19 oach could be simultaneously applied to both fasted and fed data sets.

20 Thus, PEPCK-M has a direct role in fasted and fed glucose homeostasis, and this mitochondri

21 vement of a magnetic pill in the stomachs of fasted and fed humans.

22 nesoid X receptor (FXR) are activated in the fasted and fed liver, respectively.

23 ody weight, is significantly reduced in both fasted and fed mice.

24 oxo1, mice adapted appropriately to both the fasted and fed state, and insulin suppressed hepatic glu

25 by NR1H4) are activated in the liver in the fasted and fed state, respectively.

26 Blood was drawn during the fasted and fed states and analyzed for NRLP3 inflammasom

27 aits that were best able to discriminate the fasted and fed states were more heritable and achieved g

28 spillover of chylomicron-triglyceride in the fasted and fed states, and FA stored in liver lipid drop

29 s factor correlated inversely with SI in the fasted and fed states.

30 ectivity structure were observed between the fasted and fed states.

31 mentary ways to characterize changes between fasted and fed states.

32 rmal in mice with Atg7-deficient RPE in both fasted and fed states.

33 eostomy and IAP levels were compared between fasted and fed states.

34 n, the SUR-1(-/-) mouse is hypoglycemic when fasted and hyperglycemic when glucose-loaded.

35 mic seizures induced by insulin injection in fasted and nonfasted rats.

36 ignificant lower blood glucose levels in the fasted and post-prandial states, indicating a role for p

37 psies was used to measure MPS under baseline fasted and postprandial conditions in both a rested (res

38 oxidation, and net liver fat content in the fasted and postprandial states, we used stable-isotope t

39 of several metabolic genes in the livers of fasted and refed NT and hGLUT4 TG mice.

40 Detailed c-Fos mapping comparing fasted and refed rats was performed to identify candidat

41 for tracer transport time, the animals were fasted and then refed before sacrifice.

42 ression were assessed in the postabsorptive (fasted) and postprandial (fed; 480 kcal, 20 g protein) s

43 tomated fit performed reliably in untreated, fasted, and ketamine-xylazine-treated mice, with no stat

44 Hypothalamic sections of fed, fasted, and refed animals were immunostained with cFos,

45 Fourteen fasted anesthetized mechanically ventilated domestic pig

46 K9 mimicked the impact of enteral feeding in fasted animals (p < 0.05).

47 ugh the citric acid cycle first increased in fasted animals from 35 to 71% for glucose and from 17 to

48 Livers from fasted animals had increased lactate:alanine, consistent

49 l activation and metabolism, as T cells from fasted animals had low glucose uptake and decreased abil

50 However, fasted animals maintained the anorexic response to melan

51 her leptin addition to cultured T cells from fasted animals or leptin injections to fasting animals w

52 st of these studies were performed utilizing fasted animals prior to perfusion so that a simplified m

53 Overnight fasted animals were subjected to either sham surgery or

54 ution from exogenous lactate did increase in fasted animals, but its overall contribution remained sm

55 In fasted animals, exogenous glycerol became the major cont

56 In either fed or fasted animals, glucose and glycerol provided the majori

57 e short-term survival during hypoglycemia in fasted animals, the CRR must overcome this energy-sparin

58 In fasted animals, the liver performs numerous functions th

59 , was not able to potentiate GLP-1 action in fasted animals.

60 ion further supported by food preferences in fasted animals.

61 tigated in rodent renal cortical slices from fasted animals.

62 revealed that mIndy was induced in livers of fasted as well as in high-fat-diet-streptozotocin diabet

63 Mice either fed or fasted before exposure showed similar infectivity rates.

64 controls, superfused hypothalamic slices of fasted birds treated with CART-peptide showed a signific

65 erences in average daily oxygen consumption, fasted blood glucose or plasma free fatty acids, but fas

66 ase, physical activity, food consumption and fasted blood glucose.

67 At baseline and follow-up, fasted blood samples and abdominal subcutaneous adipose

68 ictedly increased in the hypothalamus in the fasted brain.

69 moter by FOXO1 was observed in the livers of fasted but not fed mice.

70 To address this issue, fasted C3Heb/FeJ mice were treated with 300 mg/kg APAP a

71 RESEARCH DESIGN AND Conscious 60-h fasted canines were studied at three insulin levels (nea

72 Optical imaging of perfused hearts from fasted CD36(-/-) mice documented prolongation of Ca(2+)

73 ciated with the incidence of sudden death in fasted CD36(-/-) mice.

74 d dried blood spots in a follow-up of 13,879 fasted children aged 11.5 years (interquartile range 11.

75 om both studies revealed no effect of SIT on fasted circulating concentrations of glucose, insulin, a

76 his assumption, TG levels decreased in CM of fasted compared with nonfasted CM-Plin5 mice indicating

77 aim of this study was to measure the basal (fasted) concentrations of unmetabolized folic acid in th

78 /- 0.7 cigarettes per day) were studied in a fasted condition after a standardized diet.

79 in eight healthy subjects under an overnight fasted condition.

80 LCAD is deacetylated in wild-type mice under fasted conditions and by SIRT3 in vitro and in vivo; and

81 lucose uptake in BAT under thermoneutral and fasted conditions, a response that was further potentiat

82 rabinoside were twice as bioaccessible under fasted conditions, suggesting lipid-rich matrices select

83 ed fat content, measured under either fed or fasted conditions.

84 olism in Tgr5(-/-) mice in both free-fed and fasted conditions.

85 Studies were performed on 42-h-fasted conscious dogs fitted with vascular catheters.

86 Fasted conscious dogs were studied in the presence (n =

87 3-(3)H]glucose, and [U-(14)C]alanine in 20 h-fasted conscious ZDF and their lean littermates (ZCL) un

88 enes that control lipogenesis, compared with fasted control mice.

89 e congenic parental strain (Ahr(Fx/Fx)), non-fasted Cre(Alb)Ahr(Fx/Fx) mice exhibit a 4-fold increase

90 Fasted critically ill patients have larger, thicker-wall

91 Fasted CYP4A11 Tg mice exhibit 2-3-fold increases in hep

92 24 h fasted dogs were infused with somatostatin, while insuli

93 In fasted double knock-out mice, glycogen accumulation in s

94 determine whether an individual's mother had fasted during Ramadan or not.

95 In women only, adjustment for the PCF2-Fasted eliminated the HOA-diet effect on serum total- an

96 were elevated in SI stem/progenitor cells of fasted etoposide-treated mice, which importantly correla

97 ort term to maintain blood glucose levels in fasted, fat-depleted mice.

98 Our results suggest that the pair of fasted/fed blood expression profiles provide more compre

99 ffects of intranasal insulin administered to fasted female subjects were assessed.

100 tent increase in IN1 interneuron activity in fasted flies that decreased proportionally in response t

101 The participants fasted for 10 h and then consumed a 200-mL liquid meal (

102 on reached 60 mg/dL or until the subject had fasted for 10 h.

103 Volunteers fasted for 16 or 72 hours and then ate a standard meal.

104 mone and become profoundly hypoglycemic when fasted for 18-23 h.

105 They were then fasted for 23 h.

106 cific catalase increase was observed in mice fasted for 24 h.

107 a normal chow diet, fasted for 24 hours, or fasted for 24 hours and then fed for 6 hours.

108 oups that were placed on a normal chow diet, fasted for 24 hours, or fasted for 24 hours and then fed

109 nduced gut barrier dysfunction, WT mice were fasted for 48 hours +/- IAP supplementation in the drink

110 1) (non-satiation feeding, NSF) for 4 weeks, fasted for 4d (F) and then fed to satiation (SF) for 21d

111 Similar findings were obtained in mice fasted for 6 h or maintained in darkness for 3 d before

112 of glucose (GLC) or saline (SAL), then were fasted from 240-360 min.

113 -catheterized, conscious, and un-stressed 5h-fasted G4Tg and wild-type (WT) littermates.

114 of myocardial physiology) revealed that the fasted GF heart is able to sustain its performance by in

115 orylation, leading to a reduction in fed and fasted glycemia, improved glucose intolerance, decreased

116 patic content of long-chain acylcarnitine in fasted Gpat1(-/-) mice was 3-fold higher than in control

117 Subjects in the fasted group (n = 6) were deprived of food throughout th

118 Additionally, two fasted groups were nurse-deprived for two cycles before

119 However, in men who had fasted (>3 h) at blood collection, the odds ratio for pr

120 s are significantly different in the fed vs. fasted (>8 h food-deprived) state.

121 Hearts of CD36(-/-) mice (fed or fasted) had 3-fold higher SERCA2a and 40% lower phosphol

122 0.047%/hour) compared with rates observed in fasted healthy controls (0.039%/hour; 95% CI, 0.029% to

123 alue-based decision-making for food items in fasted healthy human participants.

124 ine modulates duodenal protein metabolism in fasted healthy humans, but its effects in a fed state re

125 Twenty overnight-fasted healthy, normal-weight men were IN administered 2

126 herefore, a case-control study including 120 fasted, healthy, age- and gender matched subjects with/w

127 metastases) to oral ceritinib 750 mg per day fasted (in 21 day treatment cycles) or chemotherapy (int

128 el and significantly reduced fed glucose and fasted insulin levels.

129 tite and snack intake of postprandial versus fasted intranasal insulin administration to the brain in

130 pl] concentrations was analyzed in overnight-fasted lean and obese individuals subjected to a whole-m

131 d rise in (TG)pl concentrations in overnight-fasted, lean subjects.

132 s OXPHOS in fasted liver and may explain how fasted liver adapts to increased substrate oxidation.

133 drial transcription that regulates OXPHOS in fasted liver and may explain how fasted liver adapts to

134 etabolism and lipid oxidation, is induced in fasted liver mitochondria and implicated in metabolic sy

135 hallenge of increased substrate oxidation in fasted liver remains unclear.

136 In fasted liver, SIRT3-mediated increases in substrate flux

137 LRP130 deacetylation to increased OXPHOS in fasted liver.

138 is contingent upon the dynamic equilibrium (fasted losses-fed gains) in protein turnover.

139 sting, the M-current was measured in fed and fasted male mice.

140 Using 10-hour fasted male Sprague-Dawley rats implanted with stereotax

141 oxytocin (24 IU) administered to 29 healthy, fasted male subjects on glucose homeostasis measured by

142 In fasted mammals, circulating pancreatic glucagon stimulat

143 n intakes, ED, and feeding, the RDA, WM, and fasted measures served as appropriate controls.

144 tion of hunger during food stimulation in 23 fasted men and women using PET and 2-deoxy-2[(18)F]fluor

145 -ribosylated BiP in the inactive pancreas of fasted mice and a rapid decline in this modification in

146 of ATF3 decreased the effects of ethanol in fasted mice and in cultured hepatocytes.

147 sociated with reduced hepatic cholesterol in fasted mice and reduced bile acids (BAs) in feces, with

148 prostate tissue is stimulated by glucose in fasted mice and that release of Zn(II) can be monitored

149 When fasted mice are exposed to 4 degrees C, L(2.1)KOs and D(

150 Refeeding of a chow diet to fasted mice increased CYP7A1 expression, bile acid pool

151 Metabolomic analyses of fasted mice lacking Sirt3 (sirt3(-/-)) revealed alterati

152 Thus, refeeding fasted mice rapidly and markedly stimulates transcriptio

153 We observed in livers of fasted mice that Socs3 mRNA was increased 4-fold compare

154 mol/l) clamps were done in catheterized, 5-h-fasted mice to assess insulin action and hypoglycemic co

155 es of ad libitum-fed, diet-induced obese and fasted mice to the anorectic actions of leptin were exam

156 Similar outcomes were observed in fasted mice treated with synthetic adropin.

157 Glycemia in non-fasted mice was measured weekly from days 0-28 after str

158 nbiased and targeted metabolomic analysis of fasted mice with a conditional knockout of ACOT7 in the

159 Fasted mice with hepatocyte-specific deletion of Tak1 ex

160 augmented histamine release in the cortex of fasted mice within a time window compatible to its anore

161 In both fed and fasted mice, (13)C-lactate extensively labels TCA cycle

162 ophagy genes and inhibited autophagy even in fasted mice, and feeding-mediated inhibition of macroaut

163 nregulation of GLUT4 expression in vitro, in fasted mice, and in mice subjected to diet-induced obesi

164 patic Foxo1 mRNA and FOXO1 protein levels in fasted mice, as well as fasting blood glucose levels.

165 Rather, when administered orally to fasted mice, glucose was directed toward hepatic lipogen

166 57BL/6J mice treated with leptin, but not in fasted mice, suggesting a potentially important role of

167 loss of CREBH decreased hepatic Fsp27beta in fasted mice, suggesting that CREBH plays a critical role

168 as with calorie-free "food," in both fed and fasted mice, suggesting that it is driven by the act of

169 neered lung and pancreatic cancer tumours in fasted mice, the contribution of circulating lactate to

170 rescued cytokine production of T cells from fasted mice.

171 d between intestinal mucosa of fasted vs non-fasted mice.

172 in the isolated perfused liver from fed and fasted mice.

173 ficantly increased and is similar to that in fasted mice.

174 al reprogramming of the proteasome system in fasted mice.

175 es MBH insulin signaling and WAT function in fasted mice.

176 trains sympathetic nervous outflow to WAT in fasted mice.

177 fatty acid utilization characteristic of the fasted muscle.

178 The activation of PVN neurons in both fasted Nckx4 knock-out and glucose-injected wild-type an

179 The stomachs of fasted nNOS(-/-) mice showed solid food residue and bezo

180 to increased adipose tissue lipolysis, when fasted or fed a high-fat low-carbohydrate ketogenic diet

181 Fasted or fed cohorts received abiraterone acetate doses

182 ssion to obesity related traits, whether the fasted or fed state will be the most informative is an o

183 racy classifying individuals as being in the fasted or fed state.

184 Principal components analysis of either fasted or fed-state metabolites identified one factor af

185 Compared with chow-fed C57BL/6 mice, fasted or ketogenic diet-fed mice displayed increased he

186 RS-AMPA injected into the LH of fasted or nocturnal feeding subjects elicited eating in

187 Animals were fasted or received lipid-rich enteral nutrition.

188 t and normal-weight subjects and depend on a fasted or satiated state.

189 RESEARCH DESIGN AND Rats were fasted overnight.

190 Fasted plasma glucose was marginally lower in children b

191 lood glucose or plasma free fatty acids, but fasted plasma insulin and the homeostatic model assessme

192 nborn defects in fatty acid oxidation and of fasted PPARalpha-deficient mice and while death was unaf

193 When delivered by Caesarean section, fasted RagA(GTP/GTP) neonates die almost twice as rapidl

194 asis defect correlates with the inability of fasted RagA(GTP/GTP) neonates to trigger autophagy and p

195 hile the GAR reflex is more sensitive in the fasted rat, CCK amplifies this sensitivity.

196 4E with eIF4G was maintained in the liver of fasted rats as well as in serum-deprived mouse embryo fi

197 at the onset of the nocturnal period or into fasted rats did not suppress the feeding produced by eit

198 Fasted rats exhibited significantly decreased apoE gene

199 Islets from fasted rats had reduced ISR and cytochrome c reduction i

200 ta sets obtained from the perfused livers of fasted rats receiving burn injury.

201 Fasted rats were gavaged once and chyme samples were col

202 Fasted rats were serially gavaged over a 5h period with

203 We report that, in fasted rats, an intact hypothalamic arcuate nucleus and

204 In slices from fasted rats, ghrelin activation of a postsynaptic ghreli

205 In fasted rats, glucokinase activity was specifically incre

206 In fasted rats, myocardial uptake of (18)F-FTO (0.70 +/- 0.

207 ) and significant glucose lowering in normal fasted rats.

208 the magnitude of the increase was greater in fasted rats.

209 ignificantly lowered blood glucose levels in fasted rats.

210 ach, VPyr-Cyc/VMito was only 6% in overnight fasted rats.

211 P-1 and PrRP neurons in fed rats, but not in fasted rats.

212 ts analysis factor in the fasted state (PCF2-Fasted), reflected a wide range of acylcarnitines and wa

213 was also 45% lower (P<0.05) for fed than for fasted, regardless of dietary protein and energy manipul

214 trigger greater brain reward responses in a fasted relative to a fed state.

215 metabolism to fatty acid oxidation, and the fasted response occurs much more rapidly in pregnant wom

216 ase in CREB phosphorylation is absent in the fasted RIIbeta KO hypothalamus.

217 n to fed subjects (Fed-Ghrelin) and fasting (Fasted-Saline) significantly increased the appeal of hig

218 total cholesterol to HDL cholesterol in the fasted serum (P = 0.03) and postprandial serum (P = 0.01

219 d hepatic and circulating levels of FGF21 in fasted SIRT1 LKO mice were associated with reduced hepat

220 k1 expression were reduced in hypothalami of fasted Snord116 paternal knockout (Snord116p-/m+) mice.

221 Metabolic changes in fed and fasted Sprague Dawley rats (n = 36) were studied at 9.4

222 er lutein bioaccessibility compared with the fasted state (p < 0.001).

223 principal components analysis factor in the fasted state (PCF1-Fasted), which was heavily weighted b

224 principal components analysis factor in the fasted state (PCF2-Fasted), reflected a wide range of ac

225 reater vmPFC activity in the fed than in the fasted state (t(15) = -2.56, P < 0.05).

226 sitivity and mitochondrial energetics in the fasted state and after a high-fat mixed meal.

227 Subjects arrived in a fasted state and consumed a breakfast consisting of 20%

228 gulation of fatty acid oxidation both in the fasted state and in mice consuming a high-fat, low-carbo

229 ty acid oxidation and gluconeogenesis in the fasted state and lipogenesis and glycolysis in the fed s

230 cuate nucleus (ARC) neurons sense the fed or fasted state and regulate hunger.

231 tty acid esterification was transient in the fasted state but continuous under fed conditions.

232 e change in fusiform gyrus activation in the fasted state but not in the fed state.

233 ice were similar to wild-type animals in the fasted state but paradoxically decreased after refeeding

234 ed less NLRP3 inflammasome activation in the fasted state compared with that in refed conditions.

235 istration in the postprandial but not in the fasted state decreased appetite as well as intake and ra

236 measurement and manometry were performed in fasted state for 20 minutes and for 90 minutes following

237 1 (P < 0.01), and REE was 4.5% higher in the fasted state for cohort 2 (P = 0.04).

238 329 variables measured in 15 subjects in the fasted state identified one factor, the principal compon

239 We conclude that in the overnight fasted state in healthy adults, the physiological delay

240 m leading to expression of Foxo1 gene in the fasted state is less clear.

241 netic resonance imaging was performed in the fasted state on day 6.

242 ggesting a physiologic role for SOCS3 in the fasted state that may involve glucagon and Epac.

243 04% compared with 0.039% +/- 0.007%/h in the fasted state to 0.062% +/- 0.005% compared with 0.057% +

244 04% compared with 0.039% +/- 0.007%/h in the fasted state to 0.062% +/- 0.005% compared with 0.057% +

245 support the recommendation for dosing in the fasted state to achieve consistent therapeutic exposure.

246 Food intake in the fasted state was examined 45 min after neuropeptide admi

247 The respiratory exchange ratio in the fasted state was lower with the HPA diet (P = 0.04), and

248 Following resistance exercise in the fasted state, both protein synthesis and degradation in

249 orted to protect against hypoglycemia in the fasted state, but previous data have not linked the two.

250 In the fasted state, expression of carbohydrate-responsive elem

251 Regarding subject group, in the fasted state, FRS in the ACC was more pronounced in over

252 In the fasted state, increases in catecholamine signaling promo

253 In the fasted state, increases in circulating glucagon promote

254 However, in the fasted state, muscle complex I activity was 53% lower (P

255 In the fasted state, SIRT1 promotes catabolic gene expression b

256 uantitative analysis reveals that during the fasted state, the contribution of glucose to tissue TCA

257 In the fasted state, the liver is primarily responsible for mai

258 In the fasted state, they showed FRS in the PFC (P < 0.004, t((

259 meostatic control of serum triglyceride in a fasted state.

260 rds lower in AAs versus EAs in the overnight-fasted state.

261 ght values were relatively lower compared to fasted state.

262 C(max) of 203% (3.03-fold) compared with the fasted state.

263 isposal, and is pre-disposed to entering the fasted state.

264 lucose, glycerol, and lactate under a fed or fasted state.

265 ional MRI (fMRI) scans were performed in the fasted state; the blood oxygen level-dependent (BOLD) re

266 In fasted states (0-2.5 mg bile extract/mL sample), the bio

267 es metabolic rate and food intake in fed and fasted states and suppresses glucose production without

268 food valuation signals differ in the fed and fasted states between persons with high dietary disinhib

269 y raised donors were compared in the fed and fasted states by using functional genomic, biochemical,

270 endent pathway and therefore responds to fed/fasted states of the animal.

271 cial energy source in the postabsorptive and fasted states when glucose supply is limiting.

272 describing the perfused livers under fed and fasted states, the proposed approach successfully determ

273 rotein remains elevated through both fed and fasted states.

274 and, thus, substrate partitioning in fed and fasted states.

275 a much lower GSC(A) in both the fed and the fasted states.

276 t could be similarly applied to both fed and fasted states.

277 the markedly hypoglycemic range in overnight-fasted, streptozotocin-treated Gcgr(-/-) mice.

278 glucose level also was observed in overnight-fasted, streptozotocin-treated ghrelin receptor-null mic

279 ed with control nutrition (all p < 0.05) and fasted subjects (all p < 0.05).

280 lasma levels of interleukin-10 compared with fasted subjects (p < 0.0001).

281 chemical markers were performed in overnight-fasted subjects before and after the 6-mo treatment peri

282 in glucose-depleted RBCs were measured in 26 fasted subjects.

283 In addition, fasted Tgr5(-/-) mice had increased activation of hepati

284 in (Agrp) neurons during the transition from fasted to fed to overfed state.

285 ient (RQ) by indirect calorimetry during the fasted to fed transition (e.g. mixed meal challenge) or

286 bese mice and during the transition from the fasted to the fed state, suggesting that the regulation

287 ) mRNA expression in the transition from the fasted to the fed state.

288 In all participants, FRS decreased from the fasted to the satiated state in the cingulate (P < 0.005

289 etabolic profiling to investigate the fed-to-fasted transition in PPARalpha(+/+) and PPARalpha(-/-) m

290 e protocol, participants rested and remained fasted until 1330 h.

291 Serum and fasted urine for bone markers were collected at baseline

292 Fasted venous blood samples were collected for iron isot

293 d physiological responses if delivered under fasted versus fed conditions.

294 orrelated with the induced glycolytic state (fasted versus fed groups).

295 easured changes in antioxidant expression in fasted versus fed mice.

296 account for the earlier onset of seizures in fasted versus nonfasted rats.

297 ially expressed between intestinal mucosa of fasted vs non-fasted mice.

298 fold induction of Dies1 transcript in WAT of fasted vs. fed mice, suggesting a role for Dies1 in nutr

299 ts analysis factor in the fasted state (PCF1-Fasted), which was heavily weighted by the PA:OA ratio o

300 As a model for a migrating songbird, we fasted zebra finches (Taeniopygia guttata) that had been