ライフサイエンスコーパス: father

1 nal age when not adjusted for the age of the father.

2 on was found to be mosaic in an asymptomatic father.

3 marrow transplant (BMT) from his RSV-immune father.

4 most completely compared with his unaffected father.

5 ame-shift IFNGR2 mutation inherited from her father.

6 ether it is inherited from the mother or the father.

7 shared by an XY sterile daughter and fertile father.

8 ers from that of the copy inherited from the father.

9 rwent transplant, as well as in his affected father.

10 was identified in the index patient and her father.

11 without a cohabiting, actively drug-abusing father.

12 ived a preemptive kidney transplant from his father.

13 bryos that inherit an Xist deletion from the father.

14 ers and -0.22 (-0.31 to -0.15; P < .001) for fathers.

15 robust associations were seen in mothers or fathers.

16 gnificantly elevated in offspring of exposed fathers.

17 ippocampus of the offspring and the sperm of fathers.

18 l paternal origin with higher risk for older fathers.

19 ue for EPRS from their successful extra-pair fathers.

20 control participants, 1233 mothers, and 1614 fathers.

21 not the same as conflict between mothers and fathers.

22 ability with caregiving experiences in human fathers.

23 difference in response to genetic vs. foster fathers.

24 fined, additional role for them as expectant fathers.

25 195 (66%) perpetrators were fathers.

26 uction and cytoplasmic identity of potential fathers.

27 s in wildtype offspring of Akita mothers and fathers.

28 omes for infants and increase quitting among fathers.

29 rs), 192 patients' mothers and 157 patients' fathers.

30 ed with total or cardiovascular mortality in fathers.

31 ations as safe compared to male patients and fathers.

32 s self-reported by 43% of mothers and 34% of fathers.

33 25%; OR = 2.1; 95% CI, 1.0 to 4.3; P = .05; fathers: 10% vs 20%; OR = 2.3; 95% CI, 1.0 to 5.3; P = .

34 8%; OR = 6.5; 95% CI, 3.3 to 12.6; P < .001; fathers: 10% vs 47%; OR = 7.8; 95% CI, 3.7 to 16.8; P <

35 tal paternal depression symptoms affected 82 fathers (2.3%) and were associated with perceived stress

36 =2.23-3.38), intermediate for not-lived-with fathers (2.45, 95% CI=2.14-2.79), and lowest for stepfat

37 Compared with offspring born to fathers 20 to 24 years old, offspring of fathers 45 year

38 patients (aged 12-23 years), 103 mothers and fathers, 31 siblings (aged 12-26 years), and 42 friends

39 230 immunosuppressed renal transplanted men fathered 350 children (155 on MPA/195 not on MPA).

40 and were higher in brothers (64.0; P = .04), fathers (42.9; P = .004), and males (50.7; P < .001) tha

41 to fathers 20 to 24 years old, offspring of fathers 45 years and older were at heightened risk of au

42 o [OR] = 9.9; 95% CI, 4.3 to 23.3; P < .001; fathers: 5% vs 36%; OR = 11.0; 95% CI, 4.1 to 29.6; P <

43 14%; OR = 2.9; 95% CI, 1.0 to 8.2; P = .04; fathers: 6% vs 19%; OR = 3.4; 95% CI, 1.3 to 9.0; P = .0

44 g themselves; 10060 mothers (85.1%) and 2688 fathers (83.4%), selecting other infant caregivers; and

45 atal surveys, 10958 mothers (91.0%) and 2950 fathers (88.6%) reported learning a lot about understand

46 ng as normal; 11023 mothers (92.2%) and 2923 fathers (88.9%), calming their infant, 11396 mothers (94

47 their infant, 11396 mothers (94.6%) and 3035 fathers (91.9%), calming themselves; 10060 mothers (85.1

48 regivers; and 11435 mothers (94.8%) and 3201 fathers (95.8%), that the information would decrease the

49 Men who had fathered a daughter when they were 50 years or older wer

50 ve a grandchild with autism, and men who had fathered a son when they were 50 years or older were 1.6

51 d persons inherited the mutations from their fathers, a finding that indicates perfect segregation wi

52 The literature on father absence is frequently criticized for its use of c

53 designs continue to find negative effects of father absence on offspring well-being, although the mag

54 rch designs to identify the causal effect of father absence, including studies using lagged dependent

55 interval [CI], 1.23-2.53) versus nonchewing fathers (adjusted hazard ratio, 3.28; 95% CI, 1.67-6.43)

56 fathers and that this tendency increases as fathers age.

57 In that group, the hazard ratio for fathers aged >/=35 years compared with <25 years at birt

58 The previously reported father (aged 95 years) and son (aged 64 years), and the

59 The sibling's father also carried the p.Ala13Thr variant, in whom an u

60 in a female patient with mild anemia, whose father also carries the trait and is from the Turkish ci

61 Having an older father also conferred an increased risk, with an odds ra

62 Offspring from old fathers also had transcriptional dysregulation of develo

63 Fathers also reported feeling sad, hurt, or angry when p

64 The proband inherited a deletion from his father and a missense mutation from his mother, resultin

65 Explorations of the role of the father and coparenting are also directions for future re

66 ce-site variant (c.743-1 G>T) in an affected father and daughter.

67 verage birth weight of offspring with Indian father and European mother was significantly less than t

68 Three affected family members, a father and his 2 daughters, were examined.

69 rage birth weight of offspring with European father and Indian mother was greater than that of offspr

70 , while the other half is inherited from the father and is generally discordant between mother and ch

71 s important mentors in my life, including my father and Joe Gall, who is my "Doktor Vater." In turn,

72 xplain the variability of penetrance between father and son.

73 maternal age is explained by the age of the father and that de novo mutations that occur more freque

74 larly when they feel validated as a grieving father and their child is acknowledged with reverence.

75 tures (RSSs) in a human family trio (mother, father and their child).

76 However, first his father and then his younger brother died, leaving him an

77 llar abnormalities in a family composed by a father and two affected sibs with Adams Oliver syndrome

78 male somatic phenotypes as observed in an XY father and XY daughter, respectively.

79 er reduced the scores of children of younger fathers and appeared to account for the lower offspring

80 hat in sons but was not significant, whereas fathers and daughters were not associated (OR: 1.1; 95%

81 n association between depressive symptoms in fathers and depressive symptoms in their adolescent offs

82 more frequently between siblings and between fathers and offspring than between mothers and their off

83 longer parental life span (P 6.2 x 10-6 for fathers and P 2.0 x 10-3 for mothers), consistent with e

84 The risk of ADs was very similar in mothers, fathers and siblings of OCD probands, whereas it tended

85 f witnessing threats or assaults to mothers, fathers and siblings, exposure to parental and sibling v

86 cts that more transmitted mutations arise in fathers and that this tendency increases as fathers age.

87 ind, placebo-controlled crossover design, 35 fathers and their 5-month-old infants were observed twic

88 mpaired long-term memory in both the exposed fathers and their offspring.

89 war orphans and collect information on their fathers and then paired each orphan with a nonorphan fro

90 l depression symptoms affected 153 (4.3%) of fathers and were associated with perceived stress in pre

91 platforms for parent generation (mother and father) and F1 generation (male and female progeny).

92 ifestyles (e.g., divorced mother vs. married father), and 204 faculty compared same-gender candidates

93 eterosexual secondary-caregiving fathers (SC-Fathers), and primary-caregiving homosexual fathers (PC-

94 to have experienced the death of a mother, a father, and a sibling from childhood through midlife.

95 o reared them, a "not-lived-with" biological father, and a stepfather.

96 sis, which led to examination of her mother, father, and brother, who were mildly symptomatic; all 3

97 Mother, father, and child were tested for salivary oxytocin leve

98 s, E846D from the mother and R1063H from the father, and exhibited erythrocytosis and megakaryocytic

99 ne of which was corrected for the age of the father, and found that the fit was superior for the mode

100 The study enrolled 95,278 mothers, 75,248 fathers, and 114,516 children.

101 ies, salivary oxytocin was lower in mothers, fathers, and children, and the children had lower empath

102 erior temporal sulcus (STS) comparable to SC-Fathers, and functional connectivity between amygdala an

103 Most new mutations are observed to arise in fathers, and increasing paternal age positively correlat

104 for mothers, intermediate for not-lived-with fathers, and lowest for stepfathers.

105 Analyses included 112 mothers, 103 fathers, and their 213 children (55.4% girls) at age 5,

106 ys and tested to what extent vertical (i.e., father- and/or mother-offspring relationships) or horizo

107 on abnormalities arising in the sperm of old fathers are a plausible mechanism to explain some of the

108 The offspring of younger mothers and older fathers are at risk for different mental health disorder

109 hin villages, particularly when children and fathers are coresident.

110 The finding suggests that expectant and new fathers are not at greater risk of poor mental health.

111 de novo mutations in the offspring of older fathers are not only more numerous but also occur more f

112 These findings support the involvement of fathers as well as mothers in early interventions to red

113 hed light on sex differences through work on fathers as well as mothers, are affected by psychopathol

114 ults showed that the abstinence rates of the fathers at 6 months (adjusted OR: 3.60, 95% CI: 1.41-9.2

115 ed GDM/GH risk indicator in both mothers and fathers because of shared spousal behaviors and environm

116 adult lifespan of orphans who had lost their father before birth was 2.4 y (95% CI: 0.7, 3.9 y) and w

117 f genes from her mother and one set from her father but where males receive genes only from their mot

118 nating a diploid "mother" with a tetraploid "father") but repressed in the reciprocal cross.

119 ) a selective advantage in the testes of the father, but have a deleterious effect in offspring.

120 e risk of adverse birth outcomes in children fathered by male kidney transplanted patients.

121 f knowledge regarding outcome of pregnancies fathered by men exposed to MPA.

122 We compared outcomes in pregnancies fathered by renal transplant men per whether they had be

123 Broods were fathered by up to 3 different males.

124 Health care professionals should support fathers by treating the baby who died with respect and d

125 hat heritable mutations transmitted from the father can arise from either paternal or maternal misrep

126 atients, Kell differences between mother and father can lead to maternal antibody generation and hemo

127 gically how HLA disparity between mother and father can protect against allergy.

128 Both mothers and fathers can transmit all of these altered behaviors to t

129 ute to a divergence between mother-child and father-child relationships in later life.

130 We tested the method by using a mother-father-child trio sequenced at high-coverage by Illumina

131 child with autism, compared with men who had fathered children when they were 20 to 24 years old, aft

132 blished by ROC analysis, had their chance of fathering children by IVF or ICSI reduced by nearly two-

133 xplain why younger men have a higher risk of fathering children with Down syndrome.

134 ed fathers in modern Western societies, some fathers choose not to invest in their children.

135 onse to the odour of their genetic mother or father compared to the odour of a non-relative of the sa

136 The same year, our father created the Hereditary Disease Foundation (HDF),

137 We document multiple instances of father-daughter inbreeding and high levels of intraspeci

138 Employment status, relationship status, and fathers' depression were among the sociodemographic char

139 e offspring in a given clutch than any other fathers did individually.

140 ocin and parent-infant synchrony, whereas SC-Fathers displayed greater activation in cortical circuit

141 mutation rate ratio is 3.3, and the rate in fathers doubles from age 20 to 58, whereas there is no a

142 ase-parent trios, case-mother duos, and case-father duos.

143 these men had been identified as "expectant fathers" during the previous wave.

144 PC-Fathers exhibited high amygdala activation similar to PC

145 Bereaved fathers experience overall gratitude for person-centered

146 e affected by the incubation temperature its father experiences years earlier.

147 This study was designed to evaluate fathers' experiences of stillbirth and psychosocial care

148 Fathers expressed gratitude when health care professiona

149 to test the hypothesis that if the mother or father (F1) had been exposed to their own mother's (F0)

150 er this time, 349 men were identified as new fathers (first child aged <1 year), and 224 of these men

151 Research on the psychological adjustment of fathers following VPT birth is limited.

152 after receiving haploidentical HSCT from his father for the treatment of metastatic rhabdomyosarcoma.

153 ciations with diabetes were also observed in fathers (for either, HR = 1.2, 95% CI: 1.1, 1.3; for bot

154 A sub-cohort (n = 50,736 mothers, n = 44,794 fathers) from survey data was analysed for risk factors.

155 detect uniparental disomy from child-mother-father genotype data that uses a binomial test to identi

156 Both the patient and her father had a His-58(E7) --> Leu mutation in alpha1.

157 , 42.8%-80.2%) for children whose mother and father had a history of sleepwalking.

158 ts consistently show that participants whose father had a manual (as compared to nonmanual) occupatio

159 ed inflammatory burden in participants whose father had a manual occupation, through increased plasma

160 His father had childhood type 1 diabetes in poor glycemic co

161 Affected eyes appeared ovoid on MRI and the father had thin optic nerves.

162 Daughters of overweight fathers had higher rates of carcinogen-induced mammary t

163 g of HFD mothers and F1 daughters of HFD-fed fathers had increased weight gain compared to controls.

164 The offspring of older fathers had reduced exploratory and startle behaviors an

165 in whom the index parent (315 mothers and 22 fathers) had experienced at least 2 episodes of MDD (rec

166 in the findings that the offspring of older fathers have an increased risk of both de novo mutations

167 ological studies that the offspring of older fathers have an increased risk of neurodevelopmental dis

168 f a Japanese mother and a Norwegian engineer father, he was educated in Japan and later graduated fro

169 The proband and her affected father in Family 2 were homozygous for a single nucleoti

170 following administration of OT or placebo to father in the face-to-face still-face paradigm.

171 d benefits afforded the children of invested fathers in modern Western societies, some fathers choose

172 Fathers in multiplex families have marginally greater si

173 2 and ER stress in cells from the unaffected father indicate that accumulation and/or clearance of mu

174 ocio-cultural changes dramatically increased fathers' involvement in childrearing, little is known ab

175 ther has Sickle cell anaemia (Hb SS) and his father is a carrier of heterozygous alpha-thalassemia st

176 ate whether becoming an expectant and/or new father is associated with increases in psychological dis

177 Surprisingly, the patient's father is not anemic, but he is a smoker with high level

178 Caregiving by nonparents (alloparenting) and fathers is a defining aspect of human social behavior, y

179 X6) between a diploid mother and a hexaploid father, leading to the seed abortion.

180 [SD] age at birth, 32.7 [5.3] years) and 101 fathers (mean [SD] age at birth, 34.7 [6.4] years) of 14

181 [SD] age at birth, 32.9 [4.8] years) and 110 fathers (mean [SD] age at birth, 35.9 [5.3] years) of 15

182 Women preferred divorced mothers to married fathers; men preferred mothers who took leaves to mother

183 Identifying fathers most at risk of depressive symptoms and when bes

184 Compared with cohabiting fathers, mothers had a greater reduction in risk for dru

185 ved to age 50 (n = 661,031) to offspring and fathers (n = 691,124).

186 e nicotinic receptor has become the founding father of a broad family of pentameric membrane receptor

187 King Philip II was the father of Alexander the Great.

188 eek philosopher Pythagoras is considered the father of ethical vegetarianism.

189 tenary of the death of Elie Metchnikoff, the father of innate immunity.

190 Russia, however, he is also revered as "the father of Russian physiology," because of his contributi

191 To quote Carolus Linnaeus ( 1 , p. 19), the father of taxonomy, "The first step in wisdom is to know

192 19), the father of taxonomy, "The first step in wisdom is to know

193 three of the cases, and the mildly affected father of the fourth affected individual was confirmed a

194 ntact between the alloparent and the genetic father of the young.

195 incidence of recent T. gondii infections in fathers of congenitally infected children indicates that

196 nd South America led us to determine whether fathers of congenitally infected infants in the National

197 ly more likely to acknowledge paternity than fathers of daughters.

198 Assessment of disease penetrance in 2,188 fathers of individuals with cystic fibrosis enabled assi

199 hereas it tended to be higher in mothers and fathers of TD/CTD probands (compared with siblings).

200 Mothers and fathers of VPT infants had elevated rates of depression

201 tly dispersed to the group in which they had fathered offspring more likely than expected.

202 irs, there were 241 mother-offspring and 297 father-offspring pairs with a mean (SD) offspring age of

203 n BP (N = 32,227 mother-offspring and 27,535 father-offspring pairs).

204 circumference, using data from 68,244 mother-father-offspring trios from the Norwegian Mother and Chi

205 e IPD meta-analysis (N = 5327 to 5377 mother-father-offspring trios) showed that increasing maternal

206 ng that trp53 deficiency in the germ line of father or mother did not increase CNV occurrence in the

207 und for F2 offspring of analgesic-exposed F1 fathers or mothers, we interpret this as potentially ind

208 ly maltreated by their mothers (P = .007) or fathers (P = .02) as children had a poorer immune respon

209 plain some of the observed variance in human fathers' parenting behavior.

210 -Fathers), and primary-caregiving homosexual fathers (PC-Fathers) rearing infants without maternal in

211 r, a growing body of research indicates that fathers play a significant role through presently unknow

212 tterns and micro-RNA content in the sperm of fathers, providing a potential mechanism for the transge

213 A total of 1,658 men remained "never fathers." Psychological distress was measured using the

214 their mothers (r = 0.14) compared with their fathers (r = 0.03).

215 nd primary-caregiving homosexual fathers (PC-Fathers) rearing infants without maternal involvement.

216 ce (29 of 81; 36%) of T. gondii infection in fathers, relative to the average seropositivity rate of

217 The patient's brother and father reported similar complaints including distal extr

218 Only 22/131 (16%) fathers reported feeling sad, hurt, or angry.

219 113/131 (86%) fathers reported feelings of being grateful.

220 Although the father reports that his son has always been finicky, thi

221 to the average age of a new mother and a new father, respectively, Fishers equal-investment conclusio

222 history of allergies, mother's age at birth, father's age at birth and highest parental education.

223 er generation, with every additional year of father's age contributing two mutations across the genom

224 al age effect of three mutations per year of father's age.

225 ior for the model without adjustment for the father's age.

226 Social Class) was ascertained in childhood (father's class at 10/11 y) and adulthood (42/43 years),

227 y good-your mother's baking-or very bad-your father's cooking.

228 Adult lifespan was not reduced when the father's death occurred after the infant's birth.

229 c disorders in offspring can result from the father's diet, but the mechanism remains unclear.

230 sharing) increases the average fitness of a father's gametes.

231 e of conception can epigenetically reprogram father's germ-line and modulate their daughters' birth w

232 o the number of type-specific vaccine doses, father's level of education, being from a Muslim family,

233 A father's lifetime experiences can be transmitted to his

234 Patient's and father's lymphocytes showed reduced pSTAT4, nuclear tran

235 equently modelled by the interaction between father's occupation and the highest household occupation

236 y-life social position (as determined by the father's occupational level) was associated with poor ad

237 of telomeres predicted by each year that the father's or grandfather's reproduction are delayed is eq

238 Patient's and father's peripheral blood mononuclear cells and macropha

239 EBOV RNA in the mother's breast milk and the father's seminal fluid.

240 Oxytocin administration increased father salivary OT, RSA during free play, and key parent

241 -Mothers), heterosexual secondary-caregiving fathers (SC-Fathers), and primary-caregiving homosexual

242 TD/CTD and their first- (siblings, mothers, fathers), second- (half siblings) and third-degree (cous

243 Elevated scores of the father significantly increased the risk of ASD in the ch

244 o differentiate between the Y chromosomes of father-son pairs, and imputed Y-STR genotypes.

245 Furthermore, unmarried men who father sons are significantly more likely to acknowledge

246 Among obligate carriers with affected fathers, sons, or both, 53 of 55 (96%) had abnormal base

247 Our observations revealed that fathers subjected to wheel-running for 12 wk produced of

248 nsmission for these syndromes in mothers and fathers, supporting the representativeness of results fr

249 he unexposed F1 offspring of smoking-exposed fathers supports the claim that cigarette smoke is a hum

250 Mothers, not fathers, take the lead in the endocrinological and behav

251 When transmitted by a homozygous father (Tg/Tg), the Tg fails to show imprinted expressio

252 When transmitted from a hemizygous father (+/Tg), the Xist Tg demonstrates paternal-specifi

253 prediction seems fulfilled more generally by fathers than by mothers.

254 de novo mutations in the offspring of older fathers that preferentially affect specific cellular sig

255 ers and -0.39 (-0.56 to -0.21; P < .001) for fathers; the mean (95% CI) change in anxiety score per w

256 length (LTL) is well established, with older fathers thought to pass on longer telomeres to their off

257 Among all fathers, time spent in direct childcare was linked with

258 characterization of viruses isolated from a father to son transmission event.

259 perfectly during inferred transmission from father to son, and during nearly two decades of episodes

260 modest increased risk for children of older fathers to develop ASD.

261 Mothers were more likely than fathers to have a history of mental disorder (66% v 27%)

262 contrast, evolution generally leads diploid fathers to mask mutations in their gametes to the maximu

263 nt markers identified to date explain 37% of father-to-son familial risk, 8% of which can be attribut

264 9,702) and approximately 2.4% lower risk for fathers (total ndeaths = 97,630).

265 However, only F1 fathers transmit all of them to their F2 and F3 daughter

266 om a approximately 70-repeat allele from the father (unaffected by ALS or FTLD at age 89 years) expan

267 mothers had lower birth weight, whether the father was European [Delta = -152 (95% CI -92, -212) g]

268 Exome sequencing revealed that the father was heterozygous for a de novo 5 bp deletion in M

269 ative risk (FRR) for a son, given a diseased father, was 4.03 (95% confidence interval (CI): 3.12, 5.

270 As down-regulated in daughters of overweight fathers, was activated in their mammary tissues and tumo

271 The parents and siblings of the father were healthy.

272 F1 daughters of HFD fathers were also heavier (p=0.01).

273 For example, the offspring of older fathers were at an increased risk of schizophrenia and r

274 Expectant fathers were at risk of depression symptoms if they felt

275 r mothers, associations similar to those for fathers were found for blood pressure, whereas associati

276 ality of individuals born in 1914-1916 whose fathers were killed during World War 1.

277 cts of witnessing violence toward mothers or fathers were predominantly indirect and mediated by chan

278 were more resistant to infection when their fathers were reared on medicinal milkweed, while materna

279 young mothers (and to a lesser extent young fathers) were at an increased risk for substance use dis

280 hare of such non-marital births identify the father, which can create a legal entitlement to child su

281 restricted by HLA alleles inherited from the father, which may be indicative of CTL pressure.

282 t an appointment on behalf of his fictitious father who had severe itch for several months, asked whe

283 s transmitted from the clinically unaffected father who was a mosaic carrier of the variant.

284 Interestingly his father who was heterozygous for the c.1431_1433dupAAA mu

285 Mothers and fathers who engaged in weight-related conversations had

286 l biopsies from a patient and his unaffected father, who also carries the mutation, revealed that bot

287 n is brought to his primary physician by his father, who explains that his son washes his hands a hun

288 In the proband's father, who had 0.0 logMAR visual acuity, significant co

289 spring with large expansions, but not in the father, who has the approximately 70-repeat allele.

290 lains the phenotypic differences between the father, who is a smoker, and his daughter.

291 t deletion in RASA1 that was shared with the father, who possessed a capillary stain but otherwise no

292 16,121 vs. n = 61,782) and children born to fathers with and without CD (n = 9,289 vs. n = 32,984).

293 nd a paternal sibling subcohort derived from fathers with at least 2 children.

294 aths per 100,000 person-years in children of fathers with CD, vs. 53 in controls).

295 not use antiepileptic drugs and children of fathers with epilepsy had normal development at 6 months

296 d mortality has been observed in mothers and fathers with male offspring but little is known regardin

297 xpected incidence of recent infections among fathers with serum samples collected by the 1-year visit

298 olic disease in mothers and with diabetes in fathers, with stronger associations when both GDM and GH

299 anhattan (my mother was a Vogue model and my father worked in retail), and I traveled to college at t

300 e from their mother (X(m)) and 17 from their father (X(p)).