ライフサイエンスコーパス: fatty acid transporter

1 l approaches to assess the role of NPC1 as a fatty acid transporter.

2 re independent of the role of any particular fatty acid transporter.

3 og of the Escherichia coli FadLEc long-chain fatty acid transporter.

4 pressed member of a family of six long chain fatty acid transporters.

5 but overexpressing acyl-CoA synthetase 1 and fatty acid transporter 1.

6 idney proximal tubules express transmembrane fatty acid transporter-2 (FATP2), encoded by Slc27a2, bu

7 Identification of several proteins as fatty acid transporters, and emerging evidence from gene

8 XR, PXR, and PPARgamma establishes this free fatty acid transporter as a common target of orphan nucl

9 identification of a putative plasma membrane fatty acid transporter as mitochondrial aspartate aminot

10 To this end, stable cell lines expressing fatty acid transporters as well as primary hepatocytes f

11 inactivation required the expression of the fatty-acid transporter carnitine palmitoyl transferase 1

12 ease in expression of Parkin (Park2) and the fatty acid transporter CD36 along with an increase in fa

13 ted with an increased expression of the free fatty acid transporter CD36 and several accessory lipoge

14 we identified increased translocation of the fatty acid transporter CD36 from its endosomal storage c

15 ncrease in the uptake of (14)C-palmitate and fatty acid transporter CD36 that was further exacerbated

16 Expression of the fatty acid transporter CD36 was dramatically increased i

17 translocation, plasmalemmal presence of the fatty acid transporter CD36, and myocellular lipid accum

18 cially within a subpopulation expressing the fatty acid transporter CD36.

19 A or acetyl-CoA in the absence of changes in fatty acid transporters CD36 and CPT1 or beta-hydroxyacy

20 gnaling-related genes, such as Akt2, and the fatty-acid transporter CD36.

21 GAT1, a triglyceride synthesis gene, and the fatty acid transporter, CD36.

22 rt, which are rescued by deletion of CD36, a fatty acid transporter, despite persistent activation of

23 Of three membrane fatty acid transporters expressed in adipocytes, plasma

24 The OM long-chain fatty acid transporter FadL from E. coli is a unique par

25 report crystal structures of the long-chain fatty acid transporter FadL from Escherichia coli at 2.6

26 olar) substrate binding to the OM long-chain fatty acid transporter FadL from Escherichia coli causes

27 e Escherichia coli outer membrane long-chain fatty acid transporter FadL.

28 dentification of this evolutionary conserved fatty acid transporter family will allow us to gain a be

29 port and are part of a subfamily of the FadL fatty acid transporter family.

30 Kazal-type trypsin inhibitor type 1; and the fatty acid transporter fatty acid transport protein 4 ha

31 An elevation in the levels of fatty acid transporter gene expression was also observed

32 pecifically investigate the role of the Cd36 fatty acid transporter gene in the insulin-sensitizing a

33 ments clearly establish FATP1 as a regulated fatty acid transporter in both adipose tissue and muscle

34 This suggests that FATP4 is the principal fatty acid transporter in enterocytes and may constitute

35 We also demonstrate that Mce1 functions as a fatty acid transporter in Mtb and determine that facilit

36 Hepatic expression of Cd36, a fatty acid transporter, is enhanced in obese and diabeti

37 g with the basal higher expression levels of fatty acid transporters, led accumulation of long-chain

38 CD36 by PXR and PPARgamma suggests that this fatty acid transporter may function as a common target o

39 ity of free fatty acids and the abundance of fatty acid transporters, may influence the rate of muscl

40 ing protein 1; and solute carrier family 27 (fatty acid transporter), member 2; and demonstrated that

41 er these proteins function as membrane-bound fatty acid transporters or as acyl-CoA synthetases, whic

42 ng also up-regulated placental expression of fatty acid transporter protein, metabolic signaling path

43 nd 1.4-fold up-regulation of plasma membrane fatty acid transporter/translocase proteins (glutamic-ox

44 Gene expression of fatty acid transporters was greater in abdominal than fe

45 CD36, aspartate aminotransferase, caveolin) fatty acid transporters was measured.

46 If NPC1 is a fatty acid transporter, we expect to find fatty acid acc