ライフサイエンスコーパス: febrile seizure

1 trols, P = 1.6 x 10(-9) versus MMR-unrelated febrile seizures).

2 7%, 47-66) of those children had a prolonged febrile seizure.

3 l appearing child who presents with a simple febrile seizure.

4 hannels may also predispose some children to febrile seizures.

5 ated with autosomal dominant transmission of febrile seizures.

6 ia-induced convulsions, a model of pediatric febrile seizures.

7 ptor, is linked to generalized epilepsy with febrile seizures.

8 sociated with childhood absence epilepsy and febrile seizures.

9 eizures described in 393 reports included 94 febrile seizures.

10 ile convulsions, one had PFC and one had non-febrile seizures.

11 in a 5year-old with refractory epilepsy post-febrile seizures.

12 gions failed to show evidence for linkage to febrile seizures.

13 Eighteen affected individuals had recurrent febrile seizures.

14 s findings and rarely a history of childhood febrile seizures.

15 atients, only one had a history of childhood febrile seizures.

16 Of these, nine had a history of childhood febrile seizures.

17 vaccination and controls with no history of febrile seizures.

18 to 6 years with FSE and controls with simple febrile seizures.

19 and reduced the frequency of spontaneous and febrile seizures.

20 prevention of epilepsy in some children with febrile seizures.

21 , but there is an association with childhood febrile seizures.

22 ) and without (overall n = 803) a history of febrile seizures.

23 , no association was found for rs7587026 and febrile seizures.

24 s for the management of children with simple febrile seizures.

25 ween mesial temporal sclerosis and prolonged febrile seizures.

26 n family with childhood absence epilepsy and febrile seizures.

27 itive problems in individuals suffering long febrile seizures.

28 are not a transient effect of the prolonged febrile seizures.

29 nts, in the majority of children with simple febrile seizures.

30 be evident in human children after prolonged febrile seizures.

31 ossible epileptic seizures and 220 as having febrile seizures.

32 tinct acute encephalopathy syndromes, simple febrile seizures (14), other seizures (16), acute ataxia

33 pilepsy was lower in patients with prolonged febrile seizures (14.3%, 6.3-29.4) and survivors of acut

34 ines is associated with an increased risk of febrile seizures 7 to 10 days following immunization amo

35 s associated with a 2-fold increased risk of febrile seizures 7 to 10 days following immunization com

36 ine was associated with an increased risk of febrile seizures 8 to 14 days after vaccination (relativ

37 Febrile seizures affect 2-4% of all children and have a

38 vaccination, 9 children were diagnosed with febrile seizures after the first (5.5 per 100,000 person

39 Children who had febrile seizures after vaccination were followed to iden

40 iated with vaccination, the children who had febrile seizures after vaccination were not found to be

41 is family, defining the disease phenotype as febrile seizures alone.

42 clerosis findings and a history of childhood febrile seizures and (b) no MR mesial temporal sclerosis

43 The relationship between febrile seizures and childhood immunizations is explored

44 ing the NaV1.1-R1648H mutation, which causes febrile seizures and epilepsy in humans.

45 g the relationship of animal models to human febrile seizures and epilepsy.

46 g syntaxin-1B, that are associated with both febrile seizures and epilepsy.

47 r additional CPA6 mutations in patients with febrile seizures and focal epilepsy, which encompasses t

48 effect of nimodipine in an in vivo model of febrile seizures and found that this drug dramatically r

49 ave been identified that are associated with febrile seizures and generalized seizures with febrile s

50 ly healthy infant who presented with complex febrile seizures and improved on oseltamivir without neu

51 rrent knowledge of the mechanisms underlying febrile seizures and of changes in neuronal gene express

52 Combining a new rat model of complex febrile seizures and patch clamp techniques, we determin

53 a; (3) paroxysmal extreme pain disorder; (4) febrile seizures and recently (5) small fibre sensory ne

54 These febrile seizures and their potential contribution to the

55 fractory epilepsies, often with a history of febrile seizures and with frequent hippocampal atrophy a

56 s in GABRG2 have been associated with simple febrile seizures and with genetic epilepsy syndromes, in

57 mutations in human CPA6 were associated with febrile seizures and/or temporal lobe epilepsy.

58 trols, P = 1.2 x 10(-9) versus MMR-unrelated febrile seizures) and the measles virus receptor CD46 (r

59 ayed speech, a history of febrile and/or non-febrile seizures, and a wide-based, spastic, and/or stif

60 ced threshold and accelerated propagation of febrile seizures, and decreased threshold to flurothyl-i

61 oportion of viral infections associated with febrile seizures, and may be the primary cause of the se

62 obe epilepsy with hippocampal sclerosis with febrile seizures, and open avenues for investigation of

63 A reduction in post-vaccine febrile seizures appears to be present since the introdu

64 Febrile seizures are associated with increased brain tem

65 Several rarer epilepsies featuring febrile seizures are caused by mutations in SCN1A, which

66 oseola occurs in a minority of patients, and febrile seizures are infrequently associated with primar

67 dwide incidence as high as 6.7% of children, febrile seizures are one of the most common reasons for

68 but the mechanisms underlying generation of febrile seizures are poorly understood.

69 Febrile seizures are the most common form of childhood s

70 Febrile seizures are the most common seizure disorder in

71 Febrile seizures are the most common seizure type in you

72 Febrile seizures are the most common type of development

73 Seizures induced by fever (febrile seizures) are the most common type of pathologic

74 utations in these channels are implicated in febrile seizures associated with vaccination; and impair

75 obe epilepsy with hippocampal sclerosis with febrile seizures at the sodium channel gene cluster on c

76 The number of febrile seizures attributable to the administration of D

77 A total of 7811 children were diagnosed with febrile seizures before 18 months, of whom 17 were diagn

78 d age-related seizures in early life such as febrile seizures, benign focal neonatal and infantile se

79 nsus febrile seizure phenotype, and none had febrile seizures beyond 6 years of age.

80 ing gamma2 subunit mutations associated with febrile seizures but not of wild-type alpha1beta2gamma2

81 rtussis vaccine carries an increased risk of febrile seizures, but whether this risk applies to the a

82 minent febrile seizures plus and early onset febrile seizures-but included more adults with focal epi

83 Febrile seizures can arise in response to fevers induced

84 on scans comparing children with MMR-related febrile seizures, children with febrile seizures unrelat

85 alterations in synaptic communication after febrile seizures does not support the prevalent view of

86 dies have shown that adult rats who suffered febrile seizures during development reveal memory impair

87 g a single episode of experimental prolonged febrile seizures during early postnatal development.

88 e series (SCCS) study based on children with febrile seizures during follow-up of the cohort.

89 erall, children did not have higher risks of febrile seizures during the 0 to 7 days after the 3 vacc

90 Early febrile seizures, episodes of status epilepticus as well

91 ts from an epilepsy GWAS meta-analysis and a febrile seizures (FS) GWAS are significantly more enrich

92 Experimental prolonged febrile seizures (FS) lead to structural and molecular c

93 AE), juvenile myoclonic epilepsy (JME), pure febrile seizures (FS), generalized epilepsy with febrile

94 Fever can provoke "febrile" seizures (FS).

95 urthermore, compared to controls with simple febrile seizures, FSE subjects with normal acute MRI had

96 Whether long febrile seizures (FSs) can cause epilepsy in the absence

97 Whereas most febrile seizures (FSs) carry a benign outcome, a subpopu

98 Febrile seizures (FSs) constitute the most prevalent sei

99 lenges due to a recognized increased risk of febrile seizures (FSs) when used as the first dose in th

100 In prior studies of febrile seizures (FSs), prolonged FSs were defined, abse

101 a subset of children experiencing prolonged febrile seizures (FSs), the most common type of childhoo

102 blems, including asthma, hyperbilirubinemia, febrile seizures, gastroenteritis, and, together with th

103 accelerated forgetting rate in the prolonged febrile seizure group.

104 articipant (2.9%, 0.5-14.5) in the prolonged febrile seizures group developed temporal lobe epilepsy

105 were distinctly associated with MMR-related febrile seizures, harboring the interferon-stimulated ge

106 Febrile seizures have been suspected to have a genetic b

107 in these families were generally benign, and febrile seizure history was infrequent (9.8%).

108 After experimental febrile seizures (i.e., early in the epileptogenic proce

109 tly increased following experimental complex febrile seizures in developing rats, without a change in

110 (exacerbated by mutation) may contribute to febrile seizures in GEFS+ and perhaps normal individuals

111 Furthermore, four loci were associated with febrile seizures in general, implicating the sodium chan

112 ation, R82Q, that is associated with CAE and febrile seizures in humans.

113 crocephaly, intrauterine growth retardation, febrile seizures in infancy, impaired speech, stereotypi

114 V-6 infection is a common cause of fever and febrile seizures in infants.

115 y reduces both the incidence and duration of febrile seizures in rat pups, suggesting new possibiliti

116 abolishes the long-term effects of prolonged febrile seizures in the developing brain.

117 plication of CB1 receptor antagonists during febrile seizures in vivo blocked the seizure-induced per

118 netic variants influencing susceptibility to febrile seizures, including two loci specifically associ

119 occluded by previous in vivo fever-induced (febrile) seizures, indicating a common pathway.

120 arge Utah family with 21 members affected by febrile seizures inherited as an autosomal dominant trai

121 els, in which mild impairment predisposes to febrile seizures, intermediate impairment leads to GEFS+

122 Experimental complex febrile seizures involving the immature rat hippocampus

123 Familial febrile seizures is caused by mild loss-of-function muta

124 course of an epilepsy; (ix) the prognosis of febrile seizures is generally good, with ~6-7% developin

125 ure rodent studies of experimental prolonged febrile seizures, isoform-specific changes in the expres

126 ping revealed significant evidence for a new febrile seizure locus (FEB3) on chromosome 2q23-24 with

127 Febrile seizures may be a complication in young children

128 A322D)beta2gamma2 receptors, suggesting that febrile seizures may be produced by a temperature-induce

129 lities in 26 children soon after a prolonged febrile seizure (median: 37.5 days) and compared their r

130 recommended schedule presents with a simple febrile seizure, minimal intervention should be the norm

131 tinct acute encephalopathy syndromes, simple febrile seizures (n = 14), other seizures (n = 16), acut

132 drawal, age at onset of epilepsy, history of febrile seizures, number of seizures before remission, a

133 Febrile seizures occurred after dose 1 of MMR vaccine at

134 servational study found an increased risk of febrile seizure on the day of or 1 day after vaccination

135 facilitate the enduring effects of prolonged febrile seizures on neuronal and network excitability.

136 ever generates seizures, the effects of long febrile seizures on neuronal function and the potential

137 There are significantly elevated risks of febrile seizures on the day of receipt of DTP vaccine an

138 ion was associated with an increased risk of febrile seizures on the day of the first 2 vaccinations

139 ine was associated with an increased risk of febrile seizures only on the day of vaccination (adjuste

140 ith prominent deja vu and without antecedent febrile seizures or magnetic resonance imaging abnormali

141 ed with fever, consistent with the consensus febrile seizure phenotype, and none had febrile seizures

142 pilepsy, including generalized epilepsy with febrile seizures plus (GEFS+ type 2), severe myoclonic e

143 sorders, including generalized epilepsy with febrile seizures plus (GEFS+) and severe myoclonic epile

144 yndromes including generalized epilepsy with febrile seizures plus (GEFS+) and severe myoclonic epile

145 forms of epilepsy, generalized epilepsy with febrile seizures plus (GEFS+) and severe myoclonic epile

146 gada syndrome) and generalized epilepsy with febrile seizures plus (GEFS+) associated with C-terminal

147 tations that cause generalized epilepsy with febrile seizures plus (GEFS+) have been identified previ

148 Generalized epilepsy with febrile seizures plus (GEFS+) is caused by missense muta

149 Generalised epilepsy with febrile seizures plus (GEFS+) is the most studied famili

150 re associated with the genetic epilepsy with febrile seizures plus (GEFS+) spectrum disorders in huma

151 two families with generalized epilepsy with febrile seizures plus (GEFS+) type 2.

152 ile seizures (FS), generalized epilepsy with febrile seizures plus (GEFS+), and Dravet syndrome (DS)/

153 X, associated with generalized epilepsy with febrile seizures plus (GEFS+), created a loss of functio

154 isorders including generalized epilepsy with febrile seizures plus (GEFS+),(7) severe myoclonic epile

155 d in families with generalized epilepsy with febrile seizures plus (GEFS+).

156 minantly inherited generalized epilepsy with febrile seizures plus (GEFS+).

157 identified, results in genetic epilepsy with febrile seizures plus (GEFS+).

158 ilepsy syndrome termed genetic epilepsy with febrile seizures plus (GEFS+).

159 f classical GEFS+ families-such as prominent febrile seizures plus and early onset febrile seizures-b

160 bility alleles for generalized epilepsy with febrile seizures plus and juvenile myoclonic epilepsy.

161 forms of epilepsy, generalized epilepsy with febrile seizures plus and severe myoclonic epilepsy of i

162 brile seizures and generalized seizures with febrile seizures plus pedigrees.

163 enetic disorder termed "Genetic Epilepsy and Febrile Seizures Plus" (GEFS(+)).

164 f epilepsy (GEFS+, generalized epilepsy with febrile seizures plus) in humans has been accounted for

165 In generalized epilepsy with febrile seizures plus, an autosomal dominant epilepsy sy

166 absence epilepsy, generalized epilepsy with febrile seizures plus, and Dravet syndrome or severe myo

167 ibility allele for generalized epilepsy with febrile seizures plus, are also potentiated by these DHP

168 epilepsy syndrome generalized epilepsy with febrile seizures plus, which includes a spectrum of seiz

169 a primary cause of generalized epilepsy with febrile seizures plus.

170 es associated with generalized epilepsy with febrile seizures plus.

171 l gene SCN1B linked to genetic epilepsy with febrile seizures plus.

172 Febrile seizures probably do not represent a homogeneous

173 esistant strain of Streptococcus pneumoniae, febrile seizure rates following measles-mumps-rubella-va

174 ondition, the precise cellular mechanisms of febrile seizures remain unclear.

175 Febrile seizures represent a serious adverse event follo

176 Children with a history of a prolonged febrile seizure show signs of acute hippocampal injury o

177 acute event or the duration of the prolonged febrile seizure, suggesting that the observed effect is

178 As compared with other children with febrile seizures that were not associated with vaccinati

179 ng that, in the hippocampus of rats that had febrile seizures, the long-lasting enhancement of the wi

180 Despite the high incidence of febrile seizures, their contribution to the development

181 h includes a spectrum of seizures types from febrile seizures to Dravet syndrome.

182 MMR-related febrile seizures, children with febrile seizures unrelated to vaccination and controls w

183 However, a higher risk of febrile seizures was found on the day of the first (HR,

184 2(K289M), and gamma2(Q351X)] associated with febrile seizures was highly temperature dependent.

185 mutation [alpha1(A322D)] not associated with febrile seizures was not highly temperature dependent.

186 Using an appropriate-age rat model of febrile seizures, we investigated the acute and chronic

187 dissect out variants related to a history of febrile seizures, we tested cases with mesial temporal l

188 intrinsic firing may play a critical role in febrile seizures, we tested the effect of nimodipine in

189 neurologic deficit, and history of childhood febrile seizures were recorded and correlated with MR fi

190 Febrile seizures were reported in only 2 patients (9.5%)

191 In a cohort of 172 individuals with febrile seizures, who did not develop epilepsy during pr

192 and GABRG2) have been identified that cause febrile seizures with or without epilepsy.

193 Relative incidence of febrile seizures within 0 to 7 days (0, 1-3, and 4-7 day