ライフサイエンスコーパス: felodipine

1 water solubility and high hydrophobicity of felodipine.

2 sover design, 18 healthy volunteers ingested felodipine (10 mg) with 1 of the 3 juices (240 mL).

3 h montelukast (2.8 A), troglitazone (2.7 A), felodipine (2.3 A), and 9-cis-retinoic acid (2.6 A) were

4 reatment with a single oral dose of placebo, felodipine (5 mg), metoprolol (50 mg), or enalapril (10

5 closporine for immunosuppression therapy and felodipine, a calcium channel blocker, for blood pressur

6 as amlodipine, isradipine, nicardipine, and felodipine also appear to be effective in patients with

7 It was found that felodipine and copovidone in the 5% dispersion dissolve

8 aded dispersion, partial RDDR values of both felodipine and copovidone were found to be extremely low

9 We used two of these antihypertensives (felodipine and nilvadipine) for administration to mice a

10 The increase in oral availability of felodipine and other commonly used medications when take

11 In the felodipine and placebo groups, mortality (13.8% versus 1

12 sible for enhancing the systemic exposure of felodipine and probably other CYP3A4 substrates that und

13 ete resolution of GE after the withdrawal of felodipine and the control of diabetes.

14 stallized samples of the drugs indomethacin, felodipine, and acetaminophen.

15 We also present felodipine as a specific inhibitor for oncogenic Aurora

16 of transition from amorphous to crystalline felodipine at different locations within the dosage form

17 f numerous CYP3A4 drug substrates, including felodipine, by inhibiting intestinal (but not hepatic) f

18 Felodipine exerts a well-tolerated additional sustained

19 omly assigned to double-blind treatment with felodipine extended release (5 mg BID) or placebo for 3

20 (PTX), CRF with the calcium channel blocker felodipine (F), and sham operation of the kidney (SO).

21 ically select oxidation products formed from felodipine (i.e., two chlorine atoms) and bromocriptine

22 Two formulations of poorly water-soluble felodipine in a polymeric matrix of copovidone VA64 whic

23 t juice (GFJ) and the model CYP3A4 substrate felodipine in healthy volunteers using a GFJ devoid of f

24 d displays a clinical and histologic case of felodipine-influenced GE in an undiagnosed type 2 diabet

25 ative clinical approach to the management of felodipine-influenced gingival enlargement and displays

26 Additionally, felodipine inhibition of LTCCs in primary cultures of mo

27 m for the effect of grapefruit juice on oral felodipine kinetics is its selective downregulation of C

28 biopsies were obtained endoscopically, oral felodipine kinetics were determined, and liver CYP3A4 ac

29 The smaller neutral felodipine molecule is sequestered with its dichlorophen

30 molar (clevidipine, delavirdine, etravirine, felodipine, nicardipine, nilotinib, and sorafenib) or lo

31 Clevidipine, felodipine, nicardipine, nilvadipine, and nimodipine hav

32 aking a calcium-channel blocker (amlodipine, felodipine, nifedipine, diltiazem, or verapamil).

33 -penetrant dihydropyridines (eg, nifedipine, felodipine) on parkinsonism milestones as measured by ti

34 Inhibition of LTCCs with felodipine or nifedipine induces progressive cortical ca

35 tion and atrial peptide did not persist, but felodipine prevented worsening exercise tolerance and qu

36 Felodipine retards the rate of tumor progression in a xe

37 Felodipine significantly reduced blood pressure and, at

38 l edema was the only apparent side effect of felodipine therapy.

39 binding of the common antihypertension drug felodipine to the oncogenic Aurora A kinase protein via

40 oth soluble and membrane rich fractions from felodipine treated lenses by SDS-PAGE in conjunction wit

41 Histological analyses of felodipine treated lenses revealed extensive disorganiza

42 Significantly, loss of transparency in the felodipine treated lenses was preceded by an increase in

43 Felodipine treatment led to a significant increase in ge

44 on correlated with the increase in Cmax when felodipine was taken with either the 1st or the 16th gla

45 Felodipine was withdrawn and the diabetes was controlled

46 r the curve and the maximum concentration of felodipine were significantly (P < 0.001) greater with c

47 diabetes was managed at the same time as the felodipine withdrawal, it remains difficult to speculate