ライフサイエンスコーパス: female mice

1 enal abscess (a complication that is rare in female mice).

2 increased the susceptibility of mice to EAE (female mice).

3 s manner, but was greater in livers from the female mice.

4 he brain subependymal zone of adult male and female mice.

5 onsequences on neurological outcome in adult female mice.

6 diabetes symptoms in most alpha2delta-1(-/-) female mice.

7 us accumbens, an effect seen in male but not female mice.

8 dac4 in the amygdala of ovariectomized (OVX) female mice.

9 nisms underlying this phenomenon in male and female mice.

10 e more pronounced in male mice compared with female mice.

11 sis and affects normal follicle formation in female mice.

12 iently in the intestine of male mice but not female mice.

13 of the social defeat paradigm that works in female mice.

14 dult terminal field organization in male and female mice.

15 both sexes, but more so in macrophages from female mice.

16 D2-positive projection neurons, in male and female mice.

17 high-fat feeding on offspring metabolism of female mice.

18 expressed in beta-cells equally in male and female mice.

19 al studies, VTx of virus was observed in AIR female mice.

20 ocked myofiber regeneration in both male and female mice.

21 icular nucleus (PVN) neurons in "menopausal" female mice.

22 two known biological traits between male and female mice.

23 SAT in 1-year-old obese WT and ERalpha(-/-) female mice.

24 ge, and serum increased more in male than in female mice.

25 es were prevented by systemic MR blockade in female mice.

26 amplitude and duration in Mecp2 heterozygous female mice.

27 ever, these phenotypes were observed only in female mice.

28 moke-induced increase in oxidative stress in female mice.

29 t lead to aortic remodeling and stiffness in female mice.

30 to silica compared with silica-treated sham female mice.

31 oea and the respiratory irregularity of Rett female mice.

32 responses to environmental tobacco smoke in female mice.

33 D2) genotypes in male while no difference in female mice.

34 ERbeta, to facilitate hippocampal memory in female mice.

35 ca-induced lung fibrosis than silica-treated female mice.

36 thesize a mode of action for liver tumors in female mice.

37 endently of predator stress in both male and female mice.

38 vior in male mice, but effects were mixed in female mice.

39 mygdala and mPFC in male mice and in mPFC of female mice.

40 in 3 Cre (ZP3Cre)] and Control (C1galt1(FF)) female mice.

41 GC1A expression in Ppargc1a(f/f)Alb-cre(+/0) female mice.

42 emia was induced by 5/6 nephrectomy in adult female mice.

43 months) in hemizygous male and heterozygous female mice.

44 er proportion of male mice developed CP than female mice.

45 and cervical lymph nodes of healthy male and female mice.

46 ressive-like phenotype elicited by stress in female mice.

47 se development in the upper genital tract of female mice.

48 ge-correlated variations in urinary pH among female mice.

49 significantly lower in the skin of male than female mice.

50 ride treatment in not only male, but also in female mice.

51 nt-of-origin effect on EAE susceptibility in female mice.

52 rleptinemia were also observed in HET and KO female mice.

53 improved general discrimination learning in female mice.

54 and reproductive function in aging male and female mice.

55 were more pronounced for male mice than for female mice.

56 an rhythmicity, which was more pronounced in female mice.

57 Dnmt3a, also masculinized sexual behavior in female mice.

58 to completely suppress liver inflammation in female mice.

59 results in long-term infertility in male and female mice.

60 carpine status epilepticus model in male and female mice.

61 d breathing irregularities, in both male and female mice.

62 so diminishes mechanical allodynia in CCI in female mice.

63 f initiating attack behavior directed toward female mice.

64 18)F-FLT in the urinary bladder in male than female mice.

65 eins in the hippocampus, using both male and female mice.

66 -1 (ESP1), enhances reproductive behavior in female mice.

67 AAA formation and rupture in phenotypically female mice.

68 (ES) mediates depression-related outcomes in female mice.

69 s was examined in brain slices from male and female mice.

70 s and improved the survival of male, but not female, mice.

71 bution was measured in 3 strains of male and female mice (129S6/SvEv, athymic nude, and BALB/c).

72 In sham-operated or ovariectomized female mice, 17beta-E2, P4, 17beta-E2+P4, or vehicle pel

73 (47%) was substantially higher compared with female mice (30%).

74 eater tumoral Ki-67 staining was observed in female mice (71% +/- 3% for female vs. 54% +/- 2% for ma

75 Male and female mice 8-10 weeks old were grouped (six animals in

76 2 diabetic embryopathy by feeding 4-week-old female mice a high-fat diet (HFD) (60% fat).

77 degeneration (AMD) in 12-month-old male and female mice: accumulation of autofluorescent material in

78 anical pain hypersensitivity in female mice; female mice achieved similar levels of pain hypersensiti

79 The excess risk of small airway disease in female mice after chronic smoke exposure was associated

80 pattern-reversal VEPs in Mecp2 heterozygous female mice and 34 girls with RTT.

81 sed anxiety-like behaviors in adult male and female mice and decreased acoustic startle response in a

82 68,899 increased social approach in stressed female mice and decreased social approach in male mice n

83 was reduced in BMPR-II(R899X+/-) PASMCs from female mice and hPASMCs from female patients with PAH; t

84 spiking interneurons in slices from male and female mice and in the isolated female guinea pig brain

85 ly increased vitamin D levels in the skin of female mice and normalized serum 25-hydroxyvitamin D3 an

86 aged (24.2 +/- 0.1 and 28.9 +/- 0.3 months) female mice and pre- (42.3 +/- 0.5 years) and post-menop

87 reverse stress-induced social withdrawal in female mice and reduced social interaction behavior in f

88 Mecp2 heterozygous female mice and RTT patients exhibited a similar decreas

89 We exposed pregnant outbred CD1 female mice and the male progeny was crossed for three g

90 appropriate regulation of Ctss expression in female mice and thereby modulated antigen presentation a

91 deficit in the ApoE KO mice was specific to female mice and was fully rescued in female bEKO mice.

92 pp1+/+ (C57BL/6J) mice, ovariectomized (OVX) female mice, and estrogen-treated male mice were treated

93 ved in BA metabolism between normal male and female mice, and such differences were amplified when mi

94 ock, MK886 increased survival exclusively in female mice, and this effect was abolished by testostero

95 s(G12D) -driven lung cancer between male and female mice, and we show that female sex hormones can pr

96 Female mice are also rendered infertile through rAAV-dep

97 Female mice are less susceptible to the negative metabol

98 esponse to an acoustic tone in adult male or female mice as compared with nonstressed animals.

99 n of the disease in salivary epithelium from female mice as follows: (a) improves secretory function,

100 wo-photon calcium imaging in CA1 of male and female mice, as animals performed a virtual-reality (VR)

101 cells enhances weight gain in both male and female mice, as the result of reduced physical activity.

102 high-resolution fluorescence cryo-imaging in female mice bearing metastatic 4T1 breast tumours.

103 visually evoked potentials in awake male and female mice before and after a 7 d monocular deprivation

104 leus accumbens core and anteromedial BNST in female mice but not in male mice.

105 s suppressed by 17-beta-estradiol (E2) in WT female mice but not in NOER or MOER mice.

106 ced spine synapse density in the BL of adult female mice but not in the BL of male mice.

107 ranasal OT, which reduces social approach in female mice but not male mice, increased early growth re

108 OT neurons, and OT/c-fos colocalizations in female mice but not male mice.

109 ntral bed nucleus of the stria terminalis of female mice but not male mice.

110 leptin resistance and infertility in HCD-fed female mice, but given continued HCD feeding this state

111 (AngII) administration: young male and aged female mice, but not young females, develop hypertension

112 However, if D3 production is attenuated in female mice by deletion of keratinocyte lathosterol 5-de

113 oxytocin enables pup retrieval behaviour in female mice by enhancing auditory cortical pup call resp

114 Liver damage was induced in female mice by placing them on 3,5-diethoxycarbonyl-1,4-

115 adipose tissues of ESR1 total body knockout female mice compared to wild type mice.

116 hat IRI tolerance is profoundly increased in female mice compared with that observed in male mice and

117 Female mice conditioned to associate cocaine with contex

118 opment of pulmonary hypertension in male and female mice deficient in Smad1.

119 17beta-Estradiol-treated ovariectomized female mice demonstrated increased lung levels of inflam

120 model displayed a strong sexual dimorphism: female mice developed marked cholangitis, whereas male m

121 The mammary gland of K5-Cx26 female mice developed normally and produced normal level

122 e mice developing urothelial hyperplasia and female mice developing keratinizing squamous metaplasia.

123 activity in response to stress whereas obese female mice did not.

124 nd compulsive grooming, whereas group-housed female mice display increased weight gain on high-fat di

125 markable sex differences and discovered that female mice displayed greater gene expression activation

126 GABAergic inhibition increases at puberty in female mice due to expression of extrasynaptic alpha4bet

127 nstrable serotonin (5-HT) was 30% greater in female mice during oestrus than during prooestrus or in

128 t that the co-administration of Cd and Hg to female mice during the early development of their offspr

129 dividual MLIs in the Crus II region of awake female mice during two types of oromotor activity, licki

130 ducible upper and lower UTI in both male and female mice, enabling studies of sex differences in thes

131 plementation of estrogen into ovariectomized female mice enhanced M2 polarization in vivo upon challe

132 Similar to humans, female mice exhibit far lower incidences of angiotensin

133 Individually housed HDAC4(A778T) female mice exhibit reduced effortful responding for hig

134 ed, primary mammary tumors from Muc4(ko)/NDL female mice exhibit similar latencies and growth rates a

135 marrow-derived and alveolar macrophages from female mice exhibited greater expression of M2 genes in

136 Alveolar macrophages from female mice exhibited greater expression of the IL-4Ralp

137 AgRP-LepR knock-out female mice exhibited mild obesity and adiposity as desc

138 urthermore, IL-4-stimulated macrophages from female mice exhibited more transcriptionally active hist

139 ference in reconstitution efficiencies, with female mice exhibiting a greater bias towards CD45.2 rec

140 We further demonstrate that male but not female mice exposed in utero to the C6 monoclonal antibo

141 Our data indicate that female mice exposed to ES display a behavioral and physi

142 When compared with control mice, female mice exposed to ES displayed decreased social beh

143 and therefore the development of obesity in female mice exposed to excess fat energy.

144 (IFNAR) knockout (KO) mice, and heterozygous female mice expressing a Treg-specific deletion of the I

145 as baseline heat thresholds in both male and female mice expressing Gi-DREADD were normal, 1 mg/kg cl

146 Female mice fed a high-fat diet maintain CX3CL1-CX3CR1 l

147 Shmt1(+/+) and Shmt1(-/-) female mice fed folate-replete or folate-deficient diets

148 ta and aberrant crypt foci (ACF) in C57BL/6N female mice fed various dietary interventions (control,

149 ed hypoactivity and obesity in both male and female mice fed with regular chow, increased susceptibil

150 ired for mechanical pain hypersensitivity in female mice; female mice achieved similar levels of pain

151 creased bone mass in male mice and protected female mice from bone loss following ovariectomy, which

152 Absence of ERalpha protects female mice from developing nephritis, despite the prese

153 Specifically, isolating preadolescent female mice from littermates for <24 hr increased first

154 f progestins protected immunologically naive female mice from the severe outcomes from IAV infection,

155 Female mice had 177 genes regulated by treatment with LP

156 Strikingly, we found that Calr fcKO female mice had impaired folliculogenesis and decreased

157 OVX female mice had increased lung SPP1 expression in respon

158 d of neonatal exposure, THS-treated male and female mice had significantly lower bodyweight than thei

159 In contrast, female mice heterozygous for HDAC4(A778T) display severa

160 n somatic cells, and we have also shown that female mice homozygously null for ALADIN are sterile.

161 bias, we compared outcomes between male and female mice in a model of S. aureus dermonecrosis.

162 is important for the estrogenic response in female mice in a tissue-dependent manner.

163 ersistent pain, we observed that young adult female mice in early pregnancy switch from a microglia-i

164 We also compared CMMCs in colons of female mice in oestrus with those in prooestrus.

165 y and reversibly reduces colonic motility in female mice in oestrus, but not in males or females in p

166 olactin ((125)I-prolactin) into the brain of female mice in the presence and absence of the prolactin

167 Moreover, a subset of the female mice in this paradigm display resilience, maintai

168 Female mice in which one Fgf13 allele was deleted exhibi

169 By contrast, in female mice, in which UVR does produce D3, UVR fails to

170 antagonist ICI 182,780 improved survival in female mice infected with P. aeruginosa and restored neu

171 for responses to P. aeruginosa We found that female mice inoculated with P. aeruginosa died earlier a

172 that abnormal embryonic development in aged female mice is associated with severe placentation defec

173 The decreased body weight gain in GPRKO female mice is due to the reduction in body fat mass.

174 Loss of UTX in female mice is embryonic lethal.

175 We found that female mice lacking NLRP2 are subfertile because of earl

176 Female mice lacking SYCP2L undergo a significantly highe

177 Both male and female mice lacking T-BET(+) Treg cells showed a more ag

178 le estrogen-responsive tissues, we have used female mice lacking the ability to localize ERalpha to t

179 Female mice lacking type I interferon signaling (Ifnar1(

180 Here, we report that female mice lacking Xist RNA can, surprisingly, develop

181 Male, but not female, mice lacking vGlut2 in POMC neurons were unable

182 WT control dams and nondiabetic/diabetic WT female mice mated with SOD1 transgenic male mice were an

183 In female mice, mating creates a long-lasting sensory memor

184 e and reduced social interaction behavior in female mice naive to defeat.

185 ferences in gene expression between male and female mice, neither before nor after nerve injury.

186 Homozygous knockin female mice (nuclear-only ERalpha [NOER]) show loss of r

187 Female mice of 28 inbred strains received this vaccine a

188 We used male and female mice of a doxycycline-inducible transgenic line t

189 gate these differences, we infected male and female mice of different age groups with SARS-CoV and an

190 The female mice of this strain were unable to ovulate but we

191 nt extended median lifespan in both male and female mice of two distinct genetic backgrounds.

192 Both male and female mice on a vitamin D-deficient diet manifested vit

193 In diestrous female mice, only 20-Hz activation generated significant

194 ;Krt17(-/-)relative to HPV16(tg/+) reference female mice, onset of cervical lesions is delayed and cl

195 model using ovariectomized, immune-competent female mice orthotopically injected with Py230 mammary t

196 te that deletion of miR-155 (-5p and -3p) in female mice prevents diet-induced obesity.

197 d that these phenotypes, present in male and female mice, provide novel means for examining the genet

198 , iodine-accelerated, pathogenic TSHR Abs in female mice, providing a unique model to investigate dis

199 ty and intensified anaphylactic responses in female mice, providing additional mechanistic insights i

200 Surprisingly, in both male and female mice, PTH administration significantly increased

201 EAE and paternal parent-of-origin effects in female mice, raising the possibility that a similar mech

202 To this end, female mice received dexamethasone or vehicle during the

203 emale estrogen receptor alpha-KO mice, while female mice receiving supplemental estrogen before ische

204 hloride in Runx2-overexpressing osteoporotic female mice rescued the Wnt/beta-catenin signaling in vi

205 togenesis, and lack of ovulation in male and female mice, respectively.

206 eletion of Prlr in all MPOA neurons of adult female mice resulted in profound deficits in maternal ca

207 During late pregnancy, female mice show no evidence of chronic pain whatsoever.

208 Male and female mice showed a long-term dose-dependent reduction

209 adult hemizygous male, but not heterozygous female, mice showed a slowly progressive phenotype simil

210 18, a reversible iPLA2beta inhibitor, to NOD female mice significantly reduced diabetes incidence in

211 Accordingly, testosterone treatment of female mice significantly reduced the expression of IL-1

212 rocessing and executive function in male and female mice, solely due to maternal malnutrition via hig

213 tor gene expression was reduced in wild-type female mice, suggesting that white adipose tissue plays

214 ortex in response to HFD, most pronounced in female mice that correlated to the amyloid pathology.

215 We also define a dose in female mice that does not extend lifespan, but is associ

216 Stressed female mice that received an infusion of L-368,899 into

217 after spinal cord contusion injury in adult female mice, the biosynthesis of SPM is not induced in t

218 In adipose-specific Rab10 KO female mice, the partial inhibition of stimulated glucos

219 IKV-infected male mice were mated with naive female mice, the weight of fetuses at embryonic day 18.5

220 2/3 pyramidal cell activity of male, but not female, mice, thus producing an anxiolytic effect.

221 tasis, we used Zip14 knock-out (KO) male and female mice to conduct comparative metabolic, imaging, a

222 We also exposed adult male and female mice to CUS for 12 days beginning at PND70 to det

223 X3CR1 pathway that mediate the resistance of female mice to diet-induced obesity.

224 es in young (3-4 mo) and aged adult (7-8 mo) female mice to examine the effects of HCM on the develop

225 molecular, and viral approaches in male and female mice to identify the molecular and cellular mecha

226 dization and single-cell RNA-Seq in male and female mice to provide a more comprehensive view of the

227 enital tract infection has been developed in female mice to study mechanisms by which Neisseria gonor

228 to the differential sensitivity of male and female mice to the development of silica-induced fibrosi

229 We next exposed male and female mice to the proinflammatory stimulus LPS.

230 f accelerated ovarian failure (AOF) in young female mice treated with 4-vinylcyclohexene diepoxide.

231 Following challenge with an H3N2 virus, female mice treated with progestins experienced greater

232 cause of higher nonspecific muscle uptake in female mice, tumor-to-muscle uptake ratios were greater

233 Finally, female mice, typically resistant to HFD-induced obesity

234 ident male aggressive behavior, we find that female mice undergo repeated social defeat stress and de

235 esity and metabolic dysfunction in women and female mice, understanding the mechanisms and tissue-spe

236 ohorts of Grp78(+/+) and Grp78(+/-) male and female mice up to 2 years of age in three different gene

237 immunity in challenged newborn mice born to female mice vaccinated with VSVm-ZENV containing the tra

238 Of note, in postmenopausal female mice, ventricular repolarization was impaired by

239 microparticles were administered to C57BL/6 female mice via transdermal alone and in combination wit

240 With this system, we show that female mice vocally interact with males during courtship

241 se prevention in LNA-antimiR-34a treated DCM female mice was characterized by attenuated heart enlarg

242 l cells (BMSCs) of Bag-1(+/-) (heterozygous) female mice was decreased significantly.

243 The enhanced severity of anaphylaxis in female mice was eliminated after pretreatment with an es

244 f M2-like macrophages observed in DUSP3(-/-) female mice was reduced, suggesting a role for this cell

245 e mice (P < 0.001), while the weight gain in female mice was similar (4.7 +/- 2.0 g with PBS treatmen

246 In mechanistic studies in female mice, we found that hly(+) type 1 E. coli activat

247 -1 (UCP1) in classic brown adipose tissue in female mice, we found that LXRs, especially LXRbeta, als

248 t and improved glucose tolerance in male and female mice, we observed a gender difference in EPO effe

249 Using in vivo two-photon imaging in female mice, we show that mPOA(Nts) neurons preferential

250 n vitro physiological techniques in male and female mice, we show that pulvinocortical terminals are

251 To mimic males, female mice were administered a single dose of testoster

252 er 8 to 16 weeks on a Western diet, male and female mice were assessed for atherosclerotic burden in

253 Consistent with the epidemiological data, female mice were better protected against SSTI, with red

254 Preadolescent female mice were exposed to chronic stress and examined

255 Male and female mice were exposed to chronic unpredictable stress

256 Female mice were exposed to either maternal obesogenic (

257 Pregnant female mice were exposed to PBS or HDM during pregnancy.

258 Herein, female mice were exposed to the liver carcinogen diethyl

259 ial and primary ovarian follicles from young female mice were extracted and encapsulated into biomate

260 alth of offspring, 6-week-old C57BL/6 virgin female mice were fed a chow (21%) or high-fat (60%) diet

261 C57BL/6 female mice were fed a chow (21%) or high-fat (60%) diet

262 Female mice were fed a control or HFHS diet from day (D)

263 ent, or ERalpha-AF1-deficient ovariectomized female mice were fed a high-fat diet and concomitantly a

264 Female mice were fed a standard (C) or high fat (HF) die

265 C57BL/6 female mice were fed either a control diet (10% energy f

266 To determine, female mice were fed either a control or HFD during lact

267 expression levels in fat tissues of WT obese female mice were greatly increased, whereas ERalpha and

268 age-like cell line THP1.In vivo, adult CB6F1 female mice were immunized intramuscularly with H1N1 inf

269 PDGF-alpha-syn transgenic (tg) male and female mice were immunized with GP-alone, GP-alpha-syn (

270 Albino C57 female mice were intratracheally inoculated with either

271 As in humans, TSHR/NOD.H2(h4) female mice were more prone than male mice to developing

272 Female mice were placed on control diet (CD) or folic ac

273 Here, we show that GPR30 knockout (GPRKO) female mice were protected from high-fat diet (HFD)-indu

274 Adult C57BL/6J female mice were randomly assigned to be caged with an u

275 RH neurons in brain slices from OVX+E or OVX female mice were recorded during the morning or afternoo

276 ces in disease severity and outcomes: DBA/2J female mice were relatively resistant compared to their

277 Calr mcKO male mice were fertile, but fcKO female mice were sterile despite normal mating behavior.

278 y-four hours after the last stress exposure, female mice were tested in the social interaction, sucro

279 Male and female mice were treated with 0.2 g/kg intratracheal sil

280 esponses to sequential IAV infections, adult female mice were treated with placebo or one of two prog

281 Both male and female mice were used for our study.SIGNIFICANCE STATEME

282 tantially prolongs survival in both male and female mice when administered 24 hours after radiation a

283 ephalomyelitis in adulthood in male, but not female, mice when a suboptimal disease-inducing immuniza

284 olume was restored partially in male but not female mice, whereas cortical osteopenia persisted in bo

285 contrast, SERCA2 was unchanged in hearts of female mice, whereas phosphorylated phospholamban was in

286 gnition and spatial memory in ovariectomized female mice, whereas the GPER antagonist G-15 impaired m

287 (LHFPL2(G102E)) leads to infertility in 100% female mice, which have normal ovarian development, ovul

288 significantly reduced TFH cell responses in female mice while pioglitazone and estradiol (E2) co-tre

289 t also reduced weight gain in ovariectomized female mice, while the effect was abrogated with estradi

290 (+) mice or Smad1(fl/wt);Smad5(fl/fl);Cre(+) female mice with 1 functional Smad5 or Smad1 allele had

291 Furthermore, ovariectomy or treating female mice with an estrogen receptor antagonist increas

292 TSS expression in dendritic cells (DCs) from female mice with dendritic cell-specific conditional kno

293 er, in contrast to the reported phenotype of female mice with disruptions in Pgr signaling, Pgr null

294 However, breeding of the Ctnnb1(ex3)cko female mice with males of known fertility never resulted

295 mammary tumorigenesis in MMTV-Neu transgenic female mice with or without conditional knockout (KO) of

296 o food allergy, we epicutaneously sensitized female mice with ovalbumin (OVA) followed by epicutaneou

297 Inclusion of female mice with reproductive experience in preclinical

298 Here, we compared FC derived from rs-fMRI in female mice with the underlying monosynaptic structural

299 Male, but not female, mice with placental trophoblast-specific InsR de

300 eurons expressing Gad1 mRNA in both male and female mice, with less of an effect on Gad2 expression.