ライフサイエンスコーパス: feminize

1 maintain masculinity even when unambiguously feminized.

2 oestrogen is produced and germ cells appear feminized.

3 tant gonads are highly dysgenic and possibly feminized.

4 at the gonads of egl-5 males are extensively feminized.

5 ygous for gld-3(q741) enter meiosis, but are feminized.

6 e evidence that intersex is required for the feminizing activities of Dsx(F) and that it is not regul

7 The 4.7-kb mRNA encodes the major feminizing activity of the locus, a predicted membrane r

8 TRA-3 generates a peptide predicted to have feminizing activity.

9 ans, as orthologous genes are not induced in feminized amphipods.

10 using either strategy, the male mice do not feminize, and the levels of follicle-stimulating hormone

11 like mutations in dosage compensation genes, feminize animals whose male sexual identity is somewhat

12 During oogenesis in feminized animals (fem-3), a single pair of asynapsed au

13 inized (chemically castrated) and completely feminized as adults.

14 male mouse livers and in livers of male mice feminized by continuous infusion of growth hormone (GH).

15 When cells that normally express takeout are feminized by expression of the Transformer-F protein, ma

16 masculinized by exposure to testosterone and feminized by its absence during very early development.

17 In gynanders (XX//XO mosaics) feminized by this Tra(F) transgene, functionally Sxl- ha

18 asis on mitigating masculinizing rather than feminizing EDC effects.

19 docrine balance, causing demasculinizing and feminizing effects in the male embryo, including impaire

20 but lacked ER binding capacity in vitro and feminizing effects in vivo.

21 ms of removal of steroid estrogens and their feminizing effects with other treatment options.

22 view of the now known toxicities of chronic feminizing estrogen use in older women, non-feminizing e

23 e compared the potency and efficacy of a non-feminizing estrogen, 2-(1-adamantyl)-4-methylestrone (ZY

24 rch suggests that strategies to optimize non-feminizing estrogens for use in postmenopausal women can

25 feminizing estrogen use in older women, non-feminizing estrogens may be a useful alternative for est

26 dant activity, rather than ER binding of non-feminizing estrogens such as ZYC-26, mediates their pote

27 earch to synthesis and assess a group of non-feminizing estrogens that lack ability to interact with

28 We discovered that the most effective non-feminizing estrogens were those with large bulky groups

29 retain much of the neuroprotective action of feminizing estrogens.

30 These results implicate SpGAI as the feminizing factor in spinach, and suggest that the femin

31 pts is also regulated by members of the Fox (Feminizing gene on X) protein family, and these Fox targ

32 This identification of a feminizing gene suppressed by a Y-chromosome-encoded sma

33 By preventing activation of potential feminizing genes, DMRT1 allows Sertoli cells to particip

34 ic repeats (CRISPR)-Cas9 resulted in largely feminized genetic males and the production of female iso

35 Surgical options include feminizing genital and facial surgery, breast augmentati

36 nd long-term results, voiding function after feminizing genitoplasty, and the timing of surgery.

37 In animals with a feminized germline, maturation is inhibited and oocytes

38 Loss-of-function fkh-6 mutant males have feminized gonads and often develop a vulva.

39 The unexpected observation that some Tra(F)-feminized gynanders failed to lay their eggs showed ther

40 o-X cells outside the gonad for which Tra(F)-feminized haplo-X cells cannot substitute.

41 orphology of the bulbocavernosus muscle were feminized in males exposed to anti-androgen in utero.

42 ansgene that conditionally expresses two Sxl feminizing isoforms, we find that the TIF branch is requ

43 ecreased breeding gland size, demasculinized/feminized laryngeal development, suppressed mating behav

44 orldwide have demonstrated the occurrence of feminized male fish at sites impacted by human and anima

45 ion of GA production and proteasome activity feminized male flowers.

46 uding approximately 70 genes whose depletion feminized male gonadal cells.

47 osure for up to 3 years and 9 months induced feminized male gonads, although the intersex condition w

48 female mice heterozygous for the testicular feminized male loss of function mutation in their X-link

49 r of TH-immunoreactive neurons in testicular feminized male mice as in WT males, indicating that sexu

50 cts on blood pressure, deletion of this gene feminized male mice by lowering systolic blood pressure

51 l dwarf mutant nana plant1 (na1), which also feminizes male flowers.

52 that reflected chromosomal sex, with ethanol feminizing male cells and masculinizing female cells.

53 wildtype male and female rats and testicular feminized mutant (TFM) male rats that lack functional an

54 lve this issue, mice carrying the testicular feminized mutation in the X-linked AR gene were cross-br

55 that Tra(F) is sufficient to elicit a fully feminizing nonautonomous signal, but also that haplo-X s

56 n tra alone would suffice to trigger a fully feminizing nonautonomous signal.

57 tem to manipulate transformer expression, we feminized or masculinized different populations of neuro

58 In animals with a feminized or tumorous germline, contractions are infrequ

59 l transition that enables them to respond to feminizing or masculinizing cues from fetal ovary or tes

60 gametogenesis-competent cells to respond to feminizing or masculinizing cues produced by the fetal o

61 zing factor in spinach, and suggest that the feminizing pathway is epistatic to the masculinizing pat

62 he target gene transformer (tra) to make its feminizing product, TRA-F.

63 ter treatment works (WwTW) effluents induces feminized responses in male fish, including the developm

64 ntrast, the liver of male Smst(-/-) mice was feminized, resulting in an identical profile of GH-regul

65 life as a sex chromosome, such as its minor feminizing role in sex determination or its targeting by

66 , the estrogen-synthesizing enzyme, as a key feminizing signal.

67 Generation of the nonautonomous feminizing signals was known to involve female-specific

68 the European annual plant Mercurialis annua, feminizing some of them and crossing the feminized with

69 elopmental defects, including formation of a feminized tassel, initiation of female reproductive buds

70 l glands were obtained from adult testicular feminized (Tfm) and control mice; castrated rats, guinea

71 The testicular feminized (Tfm) mouse exhibits a nonfunctional androgen

72 at the genetic level, 16 new mutations that feminize the gametophyte in the presence of antheridioge

73 male products of the tra and dsx genes could feminize the germline of XY animals.

74 f one sheath/spermathecal precursor cell can feminize the hermaphrodite germ line.

75 By contrast, the loss of STAT5b feminized the livers of males by decreasing expression o

76 ggesting that disruption of the ERalpha gene feminized the number of TH-immunoreactive neurons.

77 ese results suggest that endogenous estrogen feminizes the medulla of the bipotential turtle gonad by

78 H infusion (cGH) in male mice, which rapidly feminizes the temporal profile of liver STAT5 activity.

79 Subjects preferred feminized to average or masculinized shapes of a male fa

80 As predicted, subjects preferred feminized to average shapes of a female face.

81 We developed a constitutively feminizing tra transgene that allowed us to answer this

82 t from the observation that a constitutively feminizing tra transgene that restores fertility to tra(

83 RNA splicing mode in male germ cells and can feminize triploid intersex (2X3A) germ cells.

84 The axillary branches in maize are short and feminized whereas the axillary branches of teosinte are

85 ua, feminizing some of them and crossing the feminized with the unfeminized clones.

86 Homozygous mutant XX animals were fully feminized, with ovaries and female genitalia, but showed

87 ium vulgare We identified a 3-Mb insert of a feminizing Wolbachia genome that was recently transferre

88 germline survive, but half would inherit the feminizing Xp imprinted genes.

89 We find that Tra(F) is sufficient to feminize XY germ cells, shutting off the expression of m