ライフサイエンスコーパス: femoral neck

1 than women without knee OA (P < 0.04 at the femoral neck).

2 to 3.7 percentage points; P < 0.001) at the femoral neck.

3 0.7% (CI, -1.5% to 0.01%; P = 0.081) at the femoral neck.

4 nd 1.6% (CI, 0.4% to 2.8%; P = 0.008) at the femoral neck.

5 eatment groups had an increase in BMD at the femoral neck.

6 lder age groups, especially at the spine and femoral neck.

7 not a major feature of normal ageing of the femoral neck.

8 lacement for OA or following fracture to the femoral neck.

9 d not experience significant declines at the femoral neck.

10 Bone loss began by the midtwenties at the femoral neck.

11 over the age of 50 have osteoporosis of the femoral neck.

12 cular eccentricity and stresses in the human femoral neck.

13 d with increased bone mineral density of the femoral neck.

14 rence in standardized BMD of the ipsilateral femoral neck.

15 s associated with increased bone loss at the femoral neck.

16 Similar trends were observed in the hip and femoral neck.

17 ivity level, and bone mineral density at the femoral neck.

18 esses anterior, posterior, and medial to the femoral neck.

19 multiple radial images along the axis of the femoral neck.

20 at the lumbar spine (P = 0.038), but not the femoral neck.

21 cartilage of patients with a fracture of the femoral neck.

22 oflavones, except for a modest effect at the femoral neck.

23 ntimeter, P=0.02), 13.6 percent lower at the femoral neck (0.76+/-0.11 vs. 0.88+/-0.11 g per square c

24 Mean BMD of the femoral neck (0.88 g/cm2; 95% CI, 0.84-0.91 g/cm2 vs 0.9

25 time at multiple anatomical sites, including femoral neck (-0.08%/year per one interquartile increase

26 itamin D and placebo groups were as follows: femoral neck, +0.50+/-4.80 and -0.70+/-5.03 percent, res

27 for age and sex (lumbar spine, +0.7 +/- 1.6; femoral neck, -0.1 +/- 1.1; total hip, 0.0 +/- 1.1).

28 have increased (lumbar spine, -0.2 +/- 1.6; femoral neck, -0.6 +/- 1; total hip, -0.6 +/- 1.1; match

29 (mean Z scores: lumbar spine, -0.4 +/- 1.6; femoral neck, -0.7 +/- 1.1; total hip, -0.7 +/- 1.1).

30 difference, -0.08, 95% CI -0.13 to -0.02 for femoral neck; -0.09, 95% CI -0.15 to -0.03 for lumbar sp

31 placebo at the lumbar spine (5.4% vs 1.1 %), femoral neck (1.6% vs -1.2%), femoral trochanter (3.3% v

32 fidence interval, -2.18 to -1.01; P < 0.001; femoral neck, -1.20%; 95% confidence interval, -1.69 to

33 e loss at either the LS (-8.6+/-1.0%) or the femoral neck (-11.3+/-2.2%).

34 For the femoral neck (18 RCTs, n = 1604), isoflavone treatment s

35 at the spine (3.96%; 95% CI: 4.86%, 3.06%), femoral neck (2.39%; 95% CI: 3.61%, 1.17%), total hip (1

36 the lumbar spine (17 +/- 3%), total hip and femoral neck (24 +/- 3% and 20 +/- 4%, respectively).

37 ad, 8.51-8.73 GPa vs 9.32-9.67 GPa; P = .04; femoral neck, 3.11-3.72 GPa vs 4.39-4.82 GPa; P = .04; W

38 erences: spine, 4.4% [95% CI, 3.3% to 5.5%]; femoral neck, 3.4% [CI, 2.3% to 4.4%]).

39 e estrogen had BMD increases of 2.6% for the femoral neck; 3.6%, total hip; 2.8%, spine; and 1.2%, to

40 o 0.04 (P < 0.00001; 95% CI: 0.02, 0.05) and femoral neck (4 RCTs, n = 524) to 0.03 (P < 0.05; 95% CI

41 erve transection to a level posterior to the femoral neck (8-27 cm) depending on the length of the st

42 al, 8.1 to 12.4 percent), 5.4 percent at the femoral neck (95 percent confidence interval, 3.5 to 7.4

43 bular dysplasia, pistol grip deformity, wide femoral neck, altered femoral neck-shaft angle, appear t

44 Femoral neck analysis errors were easily detectable, but

45 There were 24 (0.9%) femoral neck analysis errors, of which 23 resulted from

46 0 or less at the lumbar spine, total hip, or femoral neck and -3.5 or more at each of the three sites

47 with daily cola intake was 3.7% lower at the femoral neck and 5.4% lower at Ward's area than of those

48 y in the year after critical illness at both femoral neck and anterior-posterior spine sites.

49 X-ray absorptiometry at the lumbar spine and femoral neck and by peripheral quantitative computed tom

50 evere CAL was associated with low BMD of the femoral neck and deleterious clinical dental parameters

51 was no association between bone loss at the femoral neck and fractures regardless of bisphosphonate

52 onide was associated with loss of BMD at the femoral neck and lumbar spine after 3 years of treatment

53 Consistent results were seen for change in femoral neck and lumbar spine BMD and across a range of

54 We measured femoral neck and lumbar spine BMD at baseline and after

55 ifference between participants in BMD at the femoral neck and lumbar spine, respectively.

56 reases bone mineral density in the spine and femoral neck and reduces risk of vertebral fracture.

57 E involves displacement between the proximal femoral neck and the femoral head at the level of the op

58 cant increase of bone mineral density at the femoral neck and the trochanteric region (13% and 15%, r

59 isone therapy, bone mineral densities of the femoral neck and the Ward triangle did not increase sign

60 There was a greater increase in femoral neck and total body BMD and bone mineral content

61 cent change in bone mineral densities at the femoral neck and total hip at 24 months and at all three

62 Loss of BMD at the femoral neck and total hip were also similar between tre

63 ge or older, with normal BMD (T score at the femoral neck and total hip, -1.00 or higher) or osteopen

64 ween-group differences were observed for the femoral neck and trochanter.

65 uted the incidence rates of fractures of the femoral neck and trochanteric region of the proximal fem

66 atients underwent baseline BMD measurements (femoral neck and/or lumbar spine) using dual x-ray absor

67 0(-12) for lumbar spine and p=1.9x10(-4) for femoral neck) and an increased risk of both osteoporotic

68 0(-10) for lumbar spine and p=3.3x10(-8) for femoral neck) and increased risk of osteoporosis (OR 1.2

69 t the lumbar spine, 2.5+/-0.4 percent at the femoral neck, and 2.0+/-0.2 percent for the total body (

70 the lumbar spine, 7.4% at total hip, 7.1% at femoral neck, and 2.3% at one-third radius.

71 the lumbar spine, 9.2% at total hip, 9.0% at femoral neck, and 2.7% at the one-third radius.

72 es in bone mineral density at the total hip, femoral neck, and distal third of the radius at all time

73 lumbar spine vertebrae 2-4, the forearm, the femoral neck, and hip.

74 red with calvaria, maxilla, lumbar vertebra, femoral neck, and iliac crest.

75 ation between stimulant use and total femur, femoral neck, and lumbar spine bone mineral content (BMC

76 (average T scores and Z scores) of the hip, femoral neck, and lumbar spine of IgE-CMA patients were

77 absorptiometric examinations of the forearm, femoral neck, and lumbar spine were performed by 11 tech

78 ctive protein (hsCRP) on BMD at the forearm, femoral neck, and lumbar spine.

79 ensity (BMD) at the lumbar spine, total hip, femoral neck, and one-third radius.

80 nd bone mineral density of the lumbar spine, femoral neck, and proximal radius were measured by dual

81 gy x-ray absorptiometry of the lumbar spine, femoral neck, and radius.

82 also observed at the total hip, total body, femoral neck, and the predominantly cortical one-third r

83 ture had lower aBMD at the spine, total hip, femoral neck, and the ultradistal radius, the last havin

84 ptiometry, was assessed at the lumbar spine, femoral neck, and total femur (grams per square centimet

85 reater decreases in BMD at the lumbar spine, femoral neck, and total hip from the end of year 1 (mean

86 ineral density of the total body, total hip, femoral neck, and trabecular bone of the lumbar spine al

87 l density from baseline at the lumbar spine, femoral neck, and trochanter by 1% to 4% and in the tota

88 included lumbar spine, total proximal femur, femoral neck, and whole-body BMD.

89 pothesis while those in human and chimpanzee femoral necks are not.

90 in bone mineral density at the total hip and femoral neck, as well as transitory increases in bone-fo

91 ageing, this thin cortical zone in the upper femoral neck became substantially thinner.

92 sal women have a bone density T score at the femoral neck between -1.0 and -2.5.

93 For bone mineral density T scores at the femoral neck, biomechanical CT analysis was highly corre

94 ; 95% CI, 0.94-0.94 g/cm2; P = .03) and mean femoral neck BMC (4.34 g; 95% CI, 4.13-4.57 g vs 4.59 g;

95 13.38 g; 95% CI, 13.25-13.51 g; P = .03) and femoral neck BMD (0.87 g/cm2; 95% CI, 0.74-0.83 g/cm2 vs

96 intakes were associated with maintenance of femoral neck BMD (FN-BMD) in men (dark fish + tuna, dark

97 the ICS group experienced 6% or more loss of femoral neck BMD (p = 0.002).

98 ink/d of alcohol had a significantly greater femoral neck BMD (P = 0.008) and lumbar spine BMD (P = 0

99 The beneficial effect of current HT use on femoral neck BMD appeared to be greater in women with hi

100 The difference in femoral neck BMD between the same dose quartiles was onl

101 the hypothesis that a major QTL controlling femoral neck BMD is located on chromosome 1p36.2-p36.3,

102 PD patients had lower hip, lumbar spine and femoral neck BMD levels compared with healthy controls;

103 The means +/- SDs of femoral neck BMD loss were -0.02 +/- 0.05 and 0.0 +/- 0.

104 Women aged 54 to 81 years with a femoral neck BMD of 0.68 g/cm2 or less (Hologic Inc, Wal

105 en and 75 black men to predict total hip and femoral neck BMD or changes in BMD.

106 Among older adults with type 2 DM, femoral neck BMD T score and FRAX score were associated

107 d hazard ratios (HRs) for 1-unit decrease in femoral neck BMD T score in women with DM were 1.88 (95%

108 Twins with hip OPH had 3.5% higher femoral neck BMD than their unaffected cotwins.

109 multipoint LOD score of 3.53 for linkage of femoral neck BMD to a quantitative trait locus (QTL) loc

110 for the A593-T598-C620 haplotype (n=85) had femoral neck BMD values 5.7% lower than those who did no

111 Bilateral femoral neck BMD values as well as knee magnetic resonan

112 t of women in the lowest tertile (p = 0.02); femoral neck BMD was 12% greater in the highest versus t

113 Heritability of femoral neck BMD was estimated as 0.51 +/- 0.13 in these

114 Femoral neck BMD was higher in women who had consumed hi

115 , supplement-induced increases in spinal and femoral neck BMD were lost within 2 y of supplement disc

116 The pattern of change in femoral neck BMD with increasing protein intake in the s

117 letal and sexual maturity, anthropometry and femoral neck BMD Z-score to control confounding effects.

118 istic curve was 0.753 for entropy, 0.608 for femoral neck BMD, and 0.698 for NSA.

119 rCl was associated with greater increases in femoral neck BMD.

120 Similar results were found for femoral neck BMD.

121 one mass, with effects that are specific for femoral neck BMD.

122 se intakes were greater had higher spine and femoral neck BMD.

123 besity was associated with a greater loss of femoral neck BMD.

124 Femoral-neck BMD also increased more in the combination

125 Women aged 55-81 with low femoral-neck BMD were enrolled in two study groups based

126 ars to 332,000 dollars, depending on age and femoral neck bone density.

127 to vegetable protein intake have more rapid femoral neck bone loss and a greater risk of hip fractur

128 lumbar spine bone mass and a reduced rate of femoral neck bone loss during lactation.

129 Similarly, changes in spine and femoral neck bone mineral contents (BMCs) were not signi

130 ry, we compared lumbar spine, total hip, and femoral neck bone mineral density (BMD) in 581 HIV-posit

131 he patients had normal lumbar spine (LS) and femoral neck bone mineral density (BMD).

132 strong relation (r = 0.71) between increased femoral neck bone mineral density and increased serum 25

133 Similarly, femoral neck bone mineral density increased more in the

134 , total energy intake, plasma vitamin D, and femoral neck bone mineral density.

135 nd associated with a significant increase in femoral neck bone mineral density; vascular calcificatio

136 The femoral-neck bone density increased by 1.2+/-0.4 percent

137 xifene increased bone mineral density in the femoral neck by 2.1 % (60 mg) and 2.4% (120 mg) and in t

138 .1% +/- 4.1% and bone mineral density in the femoral neck by 2.4% +/- 3.5%.

139 various sites, bone density measured at the femoral neck by dual-energy x-ray absorptiometry is the

140 was associated with reduced bone loss in the femoral neck compared with controls (mean +/- SD -0.29+/

141 ws thinning of the underloaded superolateral femoral neck cortex arises from the failure of walking t

142 After 3 years, BMD at the femoral neck decreased 1.78% more with ICS than with pla

143 lcitriol group), and the mean density at the femoral neck decreased by 6.2 percent (P=0.001 for compa

144 The bone mineral density at the femoral neck decreased by a mean of 1.7 percent in the a

145 Children with systemic JRA had lower femoral neck densities.

146 ral density change at both the spine and the femoral neck, even after accounting for prolactin levels

147 including 206 women and men with extreme low femoral neck (FN) BMD.

148 Lumbar spine (LS), femoral neck (FN), and distal radius (DR) bone mineral d

149 tiles and mean BMD at the lumbar spine (LS), femoral neck (FN), femoral trochanter (FT), and femoral

150 0%; n = 5) but no effect on total hip (TH), femoral neck (FN), or total body BMD or bone biomarkers.

151 mposition and whole-body, lumbar spine (LS), femoral neck (FN), trochanter, and Ward's triangle (WT)

152 for lumbar spine (LS)-, total hip (HIP)- and femoral neck (FN)-bone mineral density (BMD).

153 X-ray absorptiometry at the lumbar spine and femoral neck (FN).

154 d BMD values at the lumbar spine (LS-BMD) or femoral neck (FN-BMD) in probands.

155 bone mineral density at total femur (TFBMD), femoral neck (FNBMD), lumbar spine (LSBMD), and physicia

156 ndom-effects models for the lumbar spine and femoral neck for all studies providing isoflavones as ag

157 .2%, -1.2%) of a z score was observed at the femoral neck for each unit increase in BMD z score at ba

158 s with osteoarthritis (OA) and patients with femoral neck fracture (as normal control).

159 on in hip arthroplasty, especially following femoral neck fracture in the elderly, associated with su

160 Eligible patients with femoral neck fracture undergoing hemiarthroplasty were r

161 s and from lesion-free control subjects with femoral neck fracture was assessed by measuring malondia

162 ables discrimination of patients at risk for femoral neck fracture, and our results show the potentia

163 time of joint replacement surgery for OA or femoral neck fracture.

164 s treated with a hemiarthroplasty because of femoral neck fracture.

165 these patients had experienced a low-impact femoral neck fracture.

166 h there was a trend toward a reduced risk of femoral neck fractures in subjects with severe radiograp

167 s of diabetes mellitus, vertebral fractures, femoral neck fractures, and hip fractures were 2-5 times

168 d with cartilage obtained from patients with femoral neck fractures, the expression of both miR-140-5

169 % in women with baseline osteoporosis at the femoral neck (>2.5 SDs below the normal young adult mean

170 trend for higher annual losses of BMD at the femoral neck; however, within the raloxifene group, lowe

171 significant preservation of bone loss at the femoral neck (HR 1.56, 95% CI 1.21-2.06, P=0.0007).

172 or treating BMD loss at the lumbar spine and femoral neck in estrogen-deficient women.

173 mineral density at the lumbar spine and the femoral neck in men.

174 BMD at all 4 bone sites in women and at the femoral neck in men.

175 ion reduced bone loss from the total hip and femoral neck in those who consumed <1.5 servings of dair

176 Bone mineral density of the femoral neck increased 6+/-1 percent after 1 year (P=0.0

177 The bone mineral density at the femoral neck increased significantly more in the parathy

178 cement therapy, the rate of bone loss at the femoral neck increased with blood pressure at baseline.

179 gram to derive geometric measures, including femoral neck length, width, and centroid position.

180 After femoral neck ligature, ADC increased a mean of 27% after

181 s were associated with lower mean BMD at the femoral neck [lowest-to-highest tertiles (95% CI): 0.934

182 d by pQCT, and whole-body, lumbar spine, and femoral neck measurements by DXA.

183 Fluid adjacent to the entire length of the femoral neck, measuring at least 5 mm in width, is compa

184 consortium for lumbar spine (n = 31,800) and femoral neck (n = 32,961) BMD, and from the arcOGEN cons

185 indings, including capsular adhesions at the femoral neck, obliteration of the paralabral sulcus, lab

186 mography the distribution of bone in the mid-femoral neck of 77 proximal femurs from people who died

187 neral density T score of -2.5 or less at the femoral neck or spine to receive once-daily lasofoxifene

188 No dose-related effect was noted at the femoral neck or the spine.

189 ith base line) and no significant changes in femoral-neck or total-body bone mineral density.

190 D T score of -2.5 or lower at the total hip, femoral neck, or lumbar spine; and a history of fracture

191 in, bone-turnover biomarker, p = 0.0002) and femoral neck (osteocalcin p = 0.0025).

192 umbar spine (P < 0.001), 4.1 +/- 1.0% at the femoral neck (P < 0.001), and 4.6 +/- 0.8% at the femora

193 the L2-L4 lumbar spine vertebra (P < 0.05), femoral neck (P < 0.01), and trochanter (P < 0.01) compa

194 roups with a group x time interaction at the femoral neck (P < 0.04).

195 ols, MGUS patients had decreased aBMD at the femoral neck (P = .05) and total femur (P < .05) but no

196 lationship of severe CAL with the BMD of the femoral neck (P = 0.015), as well as a positive associat

197 2 at the hip (p = 0.005), 0.012 g/cm2 at the femoral neck (p = 0.02), 0.015 g/cm2 at the spine (p = 0

198 calcium supplements at the spine (P=0.012), femoral neck (P=0.02), total femur (P=0.003), and intert

199 th Crohn's disease (lumbar spine, P = 0.004; femoral neck, P = 0.002).

200 e more complexly loaded human and chimpanzee femoral necks probably receive more prevalent/predominan

201 IBD (lumbar spine, r = -0.103, p = 0.17 and femoral neck, r = -0.138, p = 0.07).

202 Total body (TB), femoral neck, radius (R), and spine (S) bone mineral den

203 erminate, or spherical), the femoral head-to-femoral neck ratio as an interval measure of femoral hea

204 k of hip OA increased as the femoral head-to-femoral neck ratio decreased (P for trend<0.001) and wit

205 d the prevalence of abnormal femoral head-to-femoral neck ratio in at least 1 hip was 3.70% in contro

206 , the prevalence of abnormal femoral head-to-femoral neck ratio in the unaffected hip was 2 times gre

207 ent angle, acetabular slope, femoral head-to-femoral neck ratio, and the crossover sign) and compared

208 ng of the human femoral neck, the chimpanzee femoral neck reputedly receives relatively simpler loadi

209 In boys only, femoral neck SA-BMC was also significantly and positivel

210 erval measure of femoral head shape, and the femoral neck shaft angle.

211 l grip deformity, wide femoral neck, altered femoral neck-shaft angle, appear to play an important ro

212 Bone mass at total hip, femoral neck, spine (L2-4), and whole body (WB) was dete

213 moderately reduced bone loss measured in the femoral neck, spine, and total body over the three-year

214 to their lowest baseline T score at spine or femoral neck (stratum I: T score at least -1.0; stratum

215 ctures for those found to have osteoporosis (femoral neck T score < or =-2.5), compared with no inter

216 ation of fracture prevalence was best with a femoral neck T-score of -2.0 or less and a value in the

217 alyses showed that type-1 diabetes, baseline femoral neck T-score, interleukin-2 receptor blockade, a

218 odds of fracture, even after adjustment for femoral neck T-score.

219 ronate therapy for postmenopausal women with femoral neck T-scores better than -2.5 and no history of

220 tmenopausal women 55 to 75 years of age with femoral neck T-scores between -1.5 and -2.4.

221 was normal other than mild osteopenia in the femoral neck (T score, -1.3).

222 fracture or low bone mineral density at the femoral neck (T score, lower than -4 or lower than -3 pl

223 ratio had a higher rate of bone loss at the femoral neck than did those with a low ratio (P = 0.02)

224 by a T score for bone mineral density at the femoral neck that was more than 4 SD below the mean peak

225 Compared to complex loading of the human femoral neck, the chimpanzee femoral neck reputedly rece

226 walking does not sufficiently load the upper femoral neck, the fragile zones in healthy bones may nee

227 At the femoral neck, the rate of change was -1.6% (95% confiden

228 s were measured in five regions of interest: femoral neck, the Ward triangle, trochanter, intertrocha

229 and by 3 and 6 more percentage points in the femoral neck; the 40-microg dose decreased bone mineral

230 had significantly lower areal density at the femoral neck; total, cortical, and trabecular volumetric

231 In the human femoral neck, trabecular eccentricity results in a thick

232 the anterior-posterior spine, lateral spine, femoral neck, trochanter, and total body were 4.9% (0.6%

233 %) (P=.002) and prevented bone loss from the femoral neck, trochanter, and total body, despite severe

234 of amenorrheic athletes predicted BMD at the femoral neck, trochanter, intertrochanteric region, and

235 of the anterior-posterior and lateral spine, femoral neck, trochanter, radial shaft, and total body a

236 Bone mineral density (BMD) of the femoral neck, trochanter, total femur, and lumbar spine

237 increase in the modified AHA-DLS, BMD at the femoral neck, trochanter, total hip, and lumbar spine (L

238 Bone mineral density (BMD) at the femoral neck, trochanter, total hip, and lumbar spine (L

239 tly lower BMD (P < .01) at the lumbar spine, femoral neck, trochanter, Ward triangle, intertrochanter

240 MD was measured at the proximal right femur (femoral neck, trochanter, Ward's area) with a dual-photo

241 to bone mineral density (BMD) of the spine, femoral neck, trochanter, Ward's triangle, radius, and t

242 density was measured at the proximal femur (femoral neck, Ward triangle, and trochanter) and lumbar

243 mineral density at the lumbar spine (L2-L4), femoral neck, Ward's triangle, and trochanter, both befo

244 Similar decreases were found at the femoral neck, Ward's triangle, and trochanter.

245 es (for example, bone mineral density at the femoral neck was 0.84 g/cm(2), 0.88 g/cm(2), 0.86 g/cm(2

246 en (for example, bone mineral density at the femoral neck was 0.89 g/cm(2) vs. 0.87 g/cm(2), respecti

247 reasing bone mineral density quintile at the femoral neck was 8.35, 5.74, 5.22, 5.00, and 3.38% in wo

248 ule by at least 5 mm along the length of the femoral neck was almost always seen after injection of 5

249 conferring susceptibility to low BMD of the femoral neck was located on chromosome 1p36.

250 ne mineral density (BMD) of lumbar spine and femoral neck was measured, and tryptase and histamine me

251 patients with osteopenia/osteoporosis of the femoral neck was twice that in patients with normal bone

252 BMD Z scores at the lumbar spine and femoral neck were lower in patients with IBD, and lower

253 od pressure, and bone-mineral density at the femoral neck were measured at baseline and bone densitom

254 rements of the lumbar spine (L(2-4)) and the femoral neck were obtained through 1998-1999 by using du

255 n markers (n = 2929) at the lumbar spine and femoral neck were performed in perimenopausal and early

256 Results Capsular adhesions at the anterior femoral neck were present in 12 of the 34 patients (35%)

257 ents, and capsular adhesions at the anterior femoral neck were present in 35% of patients in both gro

258 Fracture loads at the femoral neck were significantly reduced for cecal ligati

259 t, trabecular tracts in human and chimpanzee femoral necks were non-orthogonal (mean approximately 70

260 total body, lumbar spine, and hip (total and femoral neck) were evaluated by using dual-energy X-ray

261 n 5,245 women (mean age 72.6 years), a wider femoral neck with a more medial centroid position was as

262 The mean increase in bone mass of the femoral neck with estrogen alone (n = 3) was only 0.9%/y

263 vertebral fracture was related to BMD at the femoral neck, with an odds ratio of 1.6 for a 1 SD reduc