ライフサイエンスコーパス: ferredoxin

1 o the exergonic formation of H2 from reduced ferredoxin.

2 miquinone, beta-FADH(*), immediately reduces ferredoxin.

3 e two other primary redox carriers, NADH and ferredoxin.

4 xin oxidoreductase involves the reduction of ferredoxin.

5 se (FAB2) is decreased to the same degree as ferredoxin.

6 ion was highly stimulated by the addition of ferredoxin.

7 was also reduced but only in the presence of ferredoxin.

8 ctron transfer from a redox cofactor such as ferredoxin.

9 loops that form extensive interactions with ferredoxin.

10 ectobacterium spp. to obtain iron from plant ferredoxin.

11 ] protein aconitase and the [2Fe-2S] protein ferredoxin.

12 y [4Fe-4S]H is reminiscent of bacterial-type ferredoxins.

13 ironment and flavodoxins (ykuNOP) to replace ferredoxins.

14 ert new Fe-(35)S clusters into aconitase and ferredoxins.

15 stasis and the p53 pathway was transduced by ferredoxin 2, a substrate of FDXR.

16 s of proteins such as aconitase [4Fe-4S] and ferredoxin [2Fe-2S] in mitochondria.

17 structurally characterized Aquifex aeolicus ferredoxin 4 (AaeFd4) using EPR, UV-visible-NIR absorpti

18 hlamydomonas reinhardtii mutant null for the ferredoxin-5 gene (FDX5) completely ceased growth in the

19 operty never observed since the discovery of ferredoxins 50 years ago.

20 fer is observed between oxidized mNT and apo-ferredoxin (a-Fd) using UV-VIS spectroscopy and native-P

21 ase is to shuttle electrons from NADH to the ferredoxin, a reaction the enzyme has to catalyze in the

22 ochondrial CYP1B1 supported by mitochondrial ferredoxin (adrenodoxin) and ferredoxin reductase showed

23 clusters on endogenous aconitase or imported ferredoxin, although cluster biogenesis in isolated Delt

24 le isoforms of the electron transfer protein ferredoxin, although we know little about their exact fu

25 taining Clostridium acetobutylicum 2[4Fe-4S]-ferredoxin and [Fe-Fe]-hydrogenase HYDA.

26 Spectroscopic analyses revealed that ferredoxin and caffeyl-CoA were reduced simultaneously,

27 droxylase must reversibly interact with both ferredoxin and catalytic effector in order to achieve el

28 oxylase complexed with its electron transfer ferredoxin and compare them with the hydroxylase-effecto

29 ion of this process affords a second reduced ferredoxin and Dh-FADH(-) that converts crotonyl-CoA to

30 derived from NADH and transferred through a ferredoxin and ferredoxin reductase pair.

31 stitution of enzymatic activity with spinach ferredoxin and ferredoxin reductase revealed that recomb

32 gh levels, genes coding for a unique pair of ferredoxin and ferredoxin-NADP(+) reductase isoforms.

33 although its third substrate, in addition to ferredoxin and NADP(H), is as yet unknown.

34 as highly specific and strictly dependent on ferredoxin and occurred at a rate of 50 milliunits/mg of

35 broad range of electron acceptors, including ferredoxin and the nickel-dependent carbon monoxide dehy

36 stantiates the connection between flavodoxin/ferredoxin and the NiFe-hydrogenase.

37 a FBEB mechanism that leads to reduction of ferredoxin and the small protein DsrC, while in fermenta

38 domain of pectocin M2 is homologous to plant ferredoxins and allows pectocin M2 to parasitize a syste

39 those of the very few reports of all-ferrous ferredoxins and Rieske centers; they confirm the S(T) =

40 containing reductase, a Rieske-type [2Fe-2S] ferredoxin, and a Rieske-type dioxygenase.

41 and a protein-based reducing system (NADPH, ferredoxin, and ferredoxin reductase; N/F/FR) provides a

42 tic proteins, substitution of flavodoxin for ferredoxin, and modified photophysiology, all while main

43 Hydrogenases, ferredoxins, and ferredoxin-NADP(+) reductases (FNR) are

44 oxin-dependent [FeFe]-hydrogenase (HydA2), a ferredoxin- and NAD-dependent electron-bifurcating [FeFe

45 he apo form of a bacterioferritin-associated ferredoxin (apo Pa Bfd).

46 of P. aeruginosa bacterioferritin-associated ferredoxin (apo-Bfd) results in rapid reduction of the h

47 -Meyerhof pathway, and both NADH and reduced ferredoxin are generated.

48 Ferredoxins are ancient proteins and the simple alpha+be

49 Nonsynonymous polymorphisms in fd (ferredoxin), arps10 (apicoplast ribosomal protein S10),

50 xins in plant chloroplasts using the [Fe2S2] ferredoxin as a one-electron donor and as such plays a c

51 ved H2 with the physiological donor (reduced ferredoxin) as well as with standard dyes.

52 relieve O(2) stress at the level of reduced ferredoxin before H(2) production.

53 tion might be due to competition for reduced ferredoxins between ferredoxin-NADP(+) oxidoreductase an

54 losest to the hydroxylase diiron centre, how ferredoxin binds to the hydroxylase has been unclear.

55 o butyryl-CoA to the endergonic reduction of ferredoxin both with NADH.

56 mentans catalyze the endergonic reduction of ferredoxin by NADH, which is also driven by the concomit

57 hat, under specific conditions, reduction of ferredoxin by plastoquinol is possible after a rapid inc

58 e performed the functional analysis of these ferredoxins by localizing Fd, Fdx2, Fdx3, and Fdx6 to th

59 can take over at higher light, when reduced ferredoxin can accumulate.

60 e demonstrate that the addition of exogenous ferredoxins can modulate redox flux in the hydrogenase-e

61 most important sinks for reduced flavodoxin/ferredoxin (CO2-fixation and nitrate reduction), this di

62 suggests that it might be a useful mimic of ferredoxin cofactors.

63 idation of H(2), the one-electron redox by a ferredoxin complements the one-electron redox by the dii

64 Furthermore, we identify a novel ferredoxin-containing bacteriocin pectocin P, which poss

65 spinach NADPH-ferredoxin oxidoreductase, and ferredoxin could also reduce the FMN peaks.

66 O2 tolerance for a protein fusion between Cp ferredoxin (CpFd) and CpI mediated by a 15-amino acid li

67 edoxin-like Clostridium pasteurianum [Fe2S2] ferredoxin (CpFd) provide the only known examples of val

68 f valence delocalization in thioredoxin-like ferredoxin Cys-to-Ser variants and Fe-S clusters in gene

69 ormed in the reaction of Pyrococcus furiosus ferredoxin D14C with nitric oxide.

70 nomethyl ester cyclase, and Fe2S2-containing ferredoxin, demonstrating prioritized allocation of Fe w

71 g enzyme and the more well-studied monomeric ferredoxin-dependent [FeFe] hydrogenase.

72 atch culture on glucose contained, besides a ferredoxin-dependent [FeFe]-hydrogenase (HydA2), a ferre

73 brane-bound, molecular oxygen-dependent, and ferredoxin-dependent activity.

74 ase, BVR and BvdR, and of the representative ferredoxin-dependent bilin reductase, phycocyanobilin:fe

75 etrapyrrole chromophores requires members of ferredoxin-dependent bilin reductases (FDBRs).

76 PCB and PPhiB are synthesized by different ferredoxin-dependent bilin reductases (FDBRs): PPhiB is

77 he pebAB and HY2 genes, encoding alternative ferredoxin-dependent biliverdin reductases, caused uniqu

78 tive in a distinct gene, GLU1, which encodes Ferredoxin-dependent Glutamate Synthase (Fd-GOGAT).

79 with the presence of peptides identified as ferredoxin-dependent glutamate synthase (GltB2), large s

80 e proteins, the content of 3Fe-4S-containing ferredoxin-dependent glutamine oxoglutarate aminotransfe

81 o harbor one or more homologs of the simpler ferredoxin-dependent hydrogenase.

82 t due to inactivation of the H(2)-producing, ferredoxin-dependent membrane-bound hydrogenase because

83 t clade; a similar topology was observed for ferredoxin-dependent nitrite reductase (Fd-NiR), indicat

84 ne significantly decreased the efficiency of ferredoxin-dependent plastoquinone reduction by NDH in r

85 reducing power to thioredoxins (Trxs) via a ferredoxin-dependent Trx reductase.

86 We show that flavodoxin and ferredoxin directly reduce the bidirectional NiFe-hydrog

87 rotein A, but the electron flow pathway from ferredoxin does not necessarily involve rubredoxin.|

88 omologous to lysozyme, illustrating that the ferredoxin domain acts as a generic delivery module for

89 membrane, containing only a single globular ferredoxin domain connected to its cytotoxic domain by a

90 ain in the N-terminal half and the bacterial ferredoxin domain in the C-terminal half, respectively.

91 eric; SDH2N and SDH2C contain the plant-type ferredoxin domain in the N-terminal half and the bacteri

92 The ferredoxin domain of pectocin M2 is homologous to plant

93 We present evidence that the ferredoxin domain of the reductase binds to the canyon r

94 ATP and limited amounts of NADPH and reduced ferredoxin during preferential excitation of photosystem

95 A low potential electron carrier ferredoxin (E0' approximately -500 mV) is used to fuel t

96 nd ehbM, respectively), a polyferredoxin and ferredoxin (ehbK and ehbL, respectively), and an ion tra

97 -X-Cys heptapeptide located within bacterial ferredoxins, enclosing an Fe(4)S(4) metal center, is an

98 Ferredoxin (Fd) is the major iron-containing protein in

99 GR5/proton gradient regulation-like1 (PGRL1) ferredoxin (Fd) pathway, involved in recycling excess re

100 previously studied [Fe4S4] model complexes, ferredoxin (Fd), and to new data on high-potential iron-

101 icate that the physiological electron donor, ferredoxin (Fd), most favorably interacts with this clus

102 of N-terminal truncation on interaction with ferredoxin (Fd), recombinant pFNRII proteins, differing

103 ulation relies on photosynthetically reduced ferredoxin (Fd), thioredoxins (Trxs), and an Fd-dependen

104 ture, Rnf likely functions as proton-pumping ferredoxin (Fd): type-I cytochrome c oxidoreductase, whi

105 sfer electrons from NADPH to hydrogenase via ferredoxins (Fd).

106 Ferredoxins (Fds) are ferrosulfoproteins that function a

107 recursor of RuBisCO small subunit (SStp) and ferredoxin (Fdtp).

108 Escherichia coli [2Fe-2S]-ferredoxin (Fdx) is encoded by the isc operon along with

109 fur for cluster formation, and a specialized ferredoxin (Fdx) whose role is still unknown.

110 ctase (CPR), ferredoxin reductase (FdR), and ferredoxin (Fdx), all important proteins for cholesterol

111 d environments ([2Fe-2S] clusters on Rieske, ferredoxin (Fdx), and glutaredoxin), and cluster oxidati

112 model [2Fe-2S] acceptor protein E. coli apo-ferredoxin (Fdx), with the homodimer being significantly

113 Among the six known chloroplast ferredoxins (FDX1-FDX6) in C. reinhardtii, FDX1 and FDX2

114 bosomal protein genes, RPL35a and RPL23, and ferredoxin, FDX1, whose flanking regions including promo

115 Ferredoxins (FDXs) can distribute electrons originating

116 ht-dependent photosynthetic mechanism-namely ferredoxin, ferredoxin-thioredoxin reductase, and thiore

117 This study demonstrates that the NADH-ferredoxin/flavodoxin system is a fairly efficient partn

118 ons of A. fermentans contain a highly active ferredoxin/flavodoxin-NAD(+) reductase (Rnf) that cataly

119 The organism uses NAD(+) and ferredoxin for glucose oxidation to acetyl coenzyme A (a

120 acetyl-CoA to ethanol, and NADH and reduced ferredoxin for the reduction of protons to H2.

121 of the [4Fe-4S] cluster in the D14C variant ferredoxin from Pyrococcus furiosus (Pf D14C Fd).

122 Transcripts of soluble hydrogenases and ferredoxins from Acetobacterium and hydrogenases, format

123 n potential used to drive ATP synthesis, the ferredoxin-fueled, sodium-motive Rnf complex.

124 tant and in which the mutated gene encodes a ferredoxin gene (fdx).

125 h-rate control reaction is driven by reduced ferredoxin generated during phototrophic growth.

126 oteins 70 and 90, Rubisco large subunit, and ferredoxin-glutamate synthase), likely reflecting functi

127 tors, kinases, USPs, DGATs, nitroreductases, ferredoxins, heat shock proteins, and the orthologs of t

128 ive corrinoid protein, HgcA, and a 2[4Fe-4S] ferredoxin, HgcB, consistent with roles as a methyl carr

129 he basis for competition, we bioengineered a ferredoxin-hydrogenase fusion and characterized hydrogen

130 Replacing the hydrogenase with a ferredoxin-hydrogenase fusion switched the bias of elect

131 Metronidazole inhibits the ferredoxin/hydrogenase pathway of fermentative eukaryoti

132 We show that the [2Fe2S]-containing spinach ferredoxin I undergoes reaction with NO at pH 6.0, with

133 , IssA reconstitutes the [4Fe-4S] cluster in ferredoxin in vitro.

134 critical for electrostatic interaction with ferredoxin in vivo.

135 scribe a new biological reduction system for ferredoxin in which ferredoxin is reduced with CO, catal

136 t two processes, the regeneration of ATP and ferredoxin (in its reduced form), exert substantial cont

137 at is necessary for high affinity binding of ferredoxin, indicating that chloroplast NDH functions as

138 c parameters of their reactions with several ferredoxin-interacting proteins, namely nitrite reductas

139 Ferredoxin is a substrate of the desaturases and has bee

140 findings demonstrate for the first time that ferredoxin is involved in secretion of CNF1 across the i

141 sis of the fdx deletion mutant revealed that ferredoxin is involved in translocation of CNF1 across t

142 Ferredoxin is presumably docked onto NfnB close to the [

143 cal reduction system for ferredoxin in which ferredoxin is reduced with CO, catalyzed by the purified

144 echanism of the interaction between NdhS and ferredoxin is unclear.

145 FDX1, being by far the most abundant ferredoxin, is thus likely the partner of PFO in C. rein

146 Overall, the results suggest that each ferredoxin isoform has substrate specificity and that th

147 pecificity and that the presence of multiple ferredoxin isoforms allows for the allocation of reducin

148 ator of 2-hydroxyacyl-CoA dehydratases and a ferredoxin-like [2Fe-2S] cluster domain acting as electr

149 ght also be found in other enzymes bearing a ferredoxin-like allosteric domain.Active and inactive st

150 The RNA is mainly bound by the N-terminal ferredoxin-like domain (NFLD) and the THUMP domain of on

151 as a C-terminal HTH domain and an N-terminal ferredoxin-like domain.

152 Upon relaxation, refolding of the ferredoxin-like domains enables the hydrogel to recover

153 sequent collapse and aggregation of unfolded ferredoxin-like domains leads to intertwining of physica

154 All domains have the ferredoxin-like fold and a solvent-exposed loop with a M

155 Due to the low mechanical stability of the ferredoxin-like fold structure, swelling of hydrogels ca

156 -designed protein that assumes the classical ferredoxin-like fold structure.

157 x1 is a human copper (Cu) chaperone with the ferredoxin-like fold that binds Cu(I) via two Cys residu

158 perfolds such as the Rossmann-like fold, the ferredoxin-like fold, and the Greek key motif, whereas t

159 -snRNA-binding region comprising an expanded ferredoxin-like fold, which recognizes a 3'-overhang of

160 crystal structure of the enzyme reveals two ferredoxin-like folds that are also found in other RNA-b

161 loop1/alpha1 of a betaalphabetabetaalphabeta ferredoxin-like structure.

162 olution unveils a alpha/beta hydrolase and a ferredoxin-like subdomain with the Ser-His catalytic dya

163 ydromethanopterin reductases (DmrX) and that ferredoxin may serve as an electron donor.

164 rostatics, demonstrated as the inhibition of ferredoxin-mediated H(2) evolution by CaI.

165 us assays in which Ti(3+) was used to reduce ferredoxin, Na(+) transport was observed, but not a Na(+

166 Using CO-reduced ferredoxin, NAD(+) reduction was highly specific and str

167 bioenergetic coupling site, a sodium-motive ferredoxin:NAD(+) oxidoreductase (Rnf) in the acetogenic

168 ectron transfer, including ion-translocating ferredoxin:NAD(+) oxidoreductase and hydrogenases, two t

169 ther identified a putative ion-translocating ferredoxin : NADH oxidoreductase (IfoAB) that may intera

170 Genetic strategies to employ ferredoxin, NADH and NADPH most effectively in natural o

171 Instead, it exhibits non-bifurcating ferredoxin NADP oxidoreductase-type activity.

172 thionite or in the presence of P. aeruginosa ferredoxin NADP reductase (FPR) and NADPH, the heme in B

173 requires only the input of electrons from a ferredoxin NADP reductase (Pa Fpr), the release of iron

174 in patient fibroblast cells showed deficient ferredoxin NADP reductase activity and mitochondrial dys

175 y for the flavin-based enzyme NADH-dependent ferredoxin NADP(+) oxidoreductase I (NfnI) from the hype

176 f O2 sensitivity by using an assay employing ferredoxin NADP(+) reductase (FNR) to transfer electrons

177 A merodiploid ferredoxin-NADP reductase mutant produced correspondingl

178 Arabidopsis (Arabidopsis thaliana) leaf-type FERREDOXIN-NADP(+) OXIDOREDUCTASE (FNR) isoforms, the ke

179 competition for reduced ferredoxins between ferredoxin-NADP(+) oxidoreductase and hydrogenases, rath

180 hotochemically in bifurcating NADH-dependent ferredoxin-NADP(+) oxidoreductase and the non-bifurcatin

181 ime of the ASQ of bifurcating NADH-dependent ferredoxin-NADP(+) oxidoreductase I and can be an indica

182 During photosynthesis, ferredoxin-NADP(+) reductase (FNR) catalyzes the electro

183 erial [2Fe-2S] ferredoxin (PetF), reduced by ferredoxin-NADP(+) reductase (FNR) using NADPH, has been

184 s coding for a unique pair of ferredoxin and ferredoxin-NADP(+) reductase isoforms.

185 Hydrogenases, ferredoxins, and ferredoxin-NADP(+) reductases (FNR) are redox proteins t

186 NADH-dependent reduced ferredoxin:NADP oxidoreductase (NfnAB) is found in the c

187 wn target of FinR regulation, fprA (encoding ferredoxin:NADP(+) oxidoreductase), or by Escherichia co

188 The enzyme ferredoxin:NADP(+) reductase (FNR) has the potential to

189 ontain two isoproteins of the photosynthetic ferredoxin:NADP(+) reductase (pFNRI and pFNRII).

190 n production kinetics in the presence of Fd, ferredoxin:NADP(+)-oxidoreductase (FNR), and NADP(+).

191 n P. furiosus, likely affecting the pools of ferredoxin, NADPH and NADH, as well as influencing metab

192 3 with PSI-light harvesting complex I (LHCI)-ferredoxin-NADPH oxidoreductase supercomplexes.

193 Using flavodoxin hydroquinone or reduced ferredoxin obtained by electron bifurcation, Rnf can be

194 al structure of FusA we show that binding of ferredoxin occurs through specialized extracellular loop

195 ct catalytically with apparent Km = 0.26 mum ferredoxin or 0.42 mum flavodoxin.

196 (+) = butyryl-CoA + NAD(+) with Km = 1.4 mum ferredoxin or 2.0 mum flavodoxin.

197 These structures reveal that ferredoxin or effector protein binding produce different

198 from T. maritima does not use either reduced ferredoxin or NADH as a sole electron donor.

199 with concomitant reduction of low-potential ferredoxins or flavodoxins.

200 Thus, ferritin OsFER2 and ferredoxin OsFd1 mRNAs are down-regulated whereas the tr

201 hyde, catalyzed by the host-encoded aldehyde ferredoxin oxidoreductase (AOR) and heterologously expre

202 bstrate with a putative nucleus-encoded DHBV:ferredoxin oxidoreductase (GtPEBA).

203 A PEB:ferredoxin oxidoreductase (GtPEBB) was found to convert

204 n oxidoreductase (PcyA), 3Z-phytochromobilin:ferredoxin oxidoreductase (HY2) from Arabidopsis thalian

205 The cyanobacterial enzyme phycocyanobilin:ferredoxin oxidoreductase (PcyA) catalyzes the two-step

206 bilin when they expressed 3Z-phycocyanobilin:ferredoxin oxidoreductase (PcyA), 3Z-phytochromobilin:fe

207 enzyme in their biogenesis, phycocyanobilin:ferredoxin oxidoreductase (PcyA), catalyzes the overall

208 n-dependent bilin reductase, phycocyanobilin:ferredoxin oxidoreductase (PcyA).

209 nicellular eukaryotes (protists) is pyruvate:ferredoxin oxidoreductase (PFO), which decarboxylates py

210 herapeutic, amixicile, that targets pyruvate:ferredoxin oxidoreductase (PFOR), a major metabolic enzy

211 ceives its electrons via pyruvate:flavodoxin/ferredoxin oxidoreductase (PFOR)-flavodoxin/ferredoxin u

212 many Krebs cycle enzymes, including pyruvate:ferredoxin oxidoreductase (PFOR); and low transcript lev

213 biochemical reactions: the reversed pyruvate:ferredoxin oxidoreductase (rPFOR), which incorporates CO

214 ood-Ljungdahl and complete reversed pyruvate ferredoxin oxidoreductase / pyruvate-formate-lyase-depen

215 arbon compounds from acetyl-CoA via pyruvate ferredoxin oxidoreductase activity.

216 encoding the iron-containing enzyme aldehyde ferredoxin oxidoreductase and a putative ABC-type transp

217 M. girerdii encodes pyruvate-ferredoxin oxidoreductase and may be sensitive to metron

218 Pyruvate:ferredoxin oxidoreductase converted acetyl-CoA and CO(2)

219 Like other members of the 2-oxoacid:ferredoxin oxidoreductase family, OOR contains thiamine

220 because the catalytic mechanism of pyruvate:ferredoxin oxidoreductase involves the reduction of ferr

221 , C. reinhardtii also possesses the pyruvate:ferredoxin oxidoreductase PFR1, which, like pyruvate:for

222 ion routes (Wood-Ljungdahl pathway, pyruvate:ferredoxin oxidoreductase reaction and anaplerotic pathw

223 tron transfer system of NADPH, spinach NADPH-ferredoxin oxidoreductase, and ferredoxin could also red

224 n, diminished pyruvate oxidation by pyruvate ferredoxin oxidoreductase, and lowered H(2) production.

225 the pyruvate synthesis pathway via pyruvate:ferredoxin oxidoreductase, and the CO(2)-anaplerotic pat

226 hat functions as a light-driven plastocyanin-ferredoxin oxidoreductase.

227 e the mutant had significantly more pyruvate:ferredoxin oxidoreductase.

228 A-dependent pyruvate and alpha-ketoglutarate ferredoxin oxidoreductases.

229 in complex with bacterioferritin-associated ferredoxin (Pa-Bfd) at 2.0 A resolution.

230 Fe]-hydrogenase HYDA1, which uses plant type ferredoxin PETF/FDX1 (PETF) as an electron donor.

231 electrons from pyruvate to HYDA1, using the ferredoxins PETF and FDX2 as electron carriers.

232 y established, but a cyanobacterial [2Fe-2S] ferredoxin (PetF), reduced by ferredoxin-NADP(+) reducta

233 dicating that chloroplast NDH functions as a ferredoxin:plastoquinone oxidoreductase.

234 ardtii genome encodes six plant type [Fe2S2] ferredoxins, products of PETF, FDX2-FDX6.

235 This regulatory mechanism relies on ferredoxin reduced by the photosynthetic electron transp

236 n-thioredoxin (Trx) system, which depends on ferredoxin reduced by the photosynthetic electron transp

237 n partners, cytochrome P450 reductase (CPR), ferredoxin reductase (FdR), and ferredoxin (Fdx), all im

238 Ferredoxin reductase (FDXR), a target of p53, modulates

239 ADH and transferred through a ferredoxin and ferredoxin reductase pair.

240 zymatic activity with spinach ferredoxin and ferredoxin reductase revealed that recombinant CYP125A1

241 y mitochondrial ferredoxin (adrenodoxin) and ferredoxin reductase showed high aryl hydrocarbon hydrox

242 ased reducing system (NADPH, ferredoxin, and ferredoxin reductase; N/F/FR) provides all four electron

243 (iv) the basic surface residues in Pdr-like ferredoxin reductases not only define specificity for th

244 ctroscopic analyses revealed that NAD(+) and ferredoxin reduction are strictly coupled and that they

245 with the hypothesis that Rnf also catalyzes ferredoxin reduction at the expense of an electrochemica

246 NAD(+) and ferredoxin reduction both required flavin.

247 electron bifurcation to drive the endergonic ferredoxin reduction by coupling it to the exergonic NAD

248 However, hydrogen-based ferredoxin reduction is endergonic, and how the steep en

249 electron bifurcation to drive the endergonic ferredoxin reduction with NADH as reductant by coupling

250 Vice versa, endergonic ferredoxin reduction with NADH as reductant was possible

251 Because ferredoxin reduction with physiological electron donors

252 The enzyme indeed catalyzed hydrogen-based ferredoxin reduction, but required NAD(+) for this react

253 tential of the FADH(*)/FAD pair required for ferredoxin reduction.

254 One such gene, a ferredoxin-related gene, was investigated further and in

255 The oxidized ferredoxin samples were also investigated by resonance R

256 ode assignments, we conducted NRVS with D14C ferredoxin samples with (36)S substituted into the [4Fe-

257 omplex between the reductase and its cognate ferredoxin shows a short distance between the electron-d

258 The enzyme oxidizes NADH and ferredoxin simultaneously in an approximately 1:1 ratio

259 de conformation in experimentally determined ferredoxin structures revealed a pervasive right-handed

260 o overcome the shortage of NADPH and reduced ferredoxin, Synechocystis preferentially activates trans

261 table, ternary complex with a small [2Fe:2S] ferredoxin termed FeSII or the "Shethna protein II".

262 a reduced thiol-disulfide redox pair(s) and ferredoxin that are energetically coupled to H(+)/CO(2)

263 At the protein level, ferredoxin, the cytochrome-b6f complex, and Fe-containin

264 2Fe-2S proteins such as Rieske proteins and ferredoxins, the metal clusters in the mitoNEET homodime

265 TTL5 interacts specifically with Arabidopsis ferredoxin : thioredoxin reductase catalytic subunit (At

266 Our results demonstrate that the host ferredoxin : thioredoxin system can be exploited cunning

267 is proposed to have similarities to that of ferredoxin, thioredoxin reductase, in that one electron

268 dox systems exist in plant chloroplasts, the ferredoxin-thioredoxin (Trx) system, which depends on fe

269 photosynthetic mechanism-namely ferredoxin, ferredoxin-thioredoxin reductase, and thioredoxin.

270 fide bridge on the gamma-subunit through the ferredoxin-thioredoxin regulatory system.

271 izing substrate NADPH, whereas the canonical ferredoxin-thioredoxin system can take over at higher li

272 Ferredoxin:thioredoxin reductase catalyzes the reduction

273 -3-methylbut-2-enyl diphosphate synthase and ferredoxin:thioredoxin reductase suggests that HMBPP bin

274 4] center in Synechocystis sp. PCC 6803 H86Y ferredoxin:thoredoxin reductase in the accessible redox

275 utant has a defect in electron transfer from ferredoxin to CoB-S-S-CoM that causes cofactor limitatio

276 In general, binding of ferredoxin to its target proteins depends on electrostat

277 Electron transport from reduced ferredoxin to NAD(+) was coupled to electrogenic Na(+) t

278 that couples electron transfer from reduced ferredoxin to NAD(+) with the generation of a primary el

279 represents a route of electron transfer from ferredoxin to NAD.

280 e (FNR) catalyzes the electron transfer from ferredoxin to NADP(+) via its FAD cofactor.

281 a to the lumen per electron transferred from ferredoxin to plastoquinone, effectively increasing the

282 assembly proteins ISCU2, frataxin (FXN), and ferredoxin to synthesize Fe-S clusters.

283 ns reoxidize the fully reduced flavodoxin or ferredoxin to the semi-reduced species.

284 However, only the natural ferredoxin topology provides a significant network of ba

285 Second, the fate of GFP fused to a ferredoxin transit peptide (FD5-GFP) was determined.

286 ne, none of the proteins were reduced by the ferredoxin-Trx reductase.

287 that falls between those of Rieske-type and ferredoxin-type [2Fe-2S] clusters.

288 oteins involved in nitrogen fixation contain ferredoxin-type [4Fe4S] clusters that exist in paramagne

289 /ferredoxin oxidoreductase (PFOR)-flavodoxin/ferredoxin under fermentative conditions, enabling the c

290 1,5-bis-phosphate carboxylase/oxygenase, and ferredoxin, we exposed these two modes of recognition.

291 ed protein can mimic the function of natural ferredoxins: we show here that reduced DSD-Fdm transfers

292 SufB and ferredoxin were early targets of transcript down-regulat

293 educe the low-potential [4Fe-4S] clusters of ferredoxin, which increases the efficiency of the substr

294 er resemble those in low-potential bacterial ferredoxins, while its ligation to three cysteine residu

295 ans produced in Escherichia coli can replace ferredoxin with almost equal efficiency.

296 upling H2 production to oxidation of reduced ferredoxin with generation of a sodium ion gradient.

297 rsibly catalyzes the endergonic reduction of ferredoxin with NADPH driven by the exergonic transhydro

298 avorable production of hydrogen from reduced ferredoxin with the unfavorable production of hydrogen f

299 is Article, we replicate the function of the ferredoxins with the redox-active ligand Cp*Fe(C(5)Me(4)

300 tes in yeast frataxin Yfh1p-deleted or yeast ferredoxin Yah1p-depleted cells.