ライフサイエンスコーパス: fetal liver cell

1 between the three-dimensional liver bud and fetal liver cells.

2 rentiation, and maturation in JAK2-deficient fetal liver cells.

3 beta-globin locus control region (LCR) using fetal liver cells.

4 veloped in mice that received CD18-deficient fetal liver cells.

5 r gamma-chain double-mutant mice with Syk-/- fetal liver cells.

6 d) mice, 3) rat bone marrow cells, or 4) rat fetal liver cells.

7 en upon expression of either gp55 in EpoR-/- fetal liver cells.

8 orming unit-erythroid (CFU-E) progenitors in fetal liver cells.

9 show here that gp55-A activates the EpoR in fetal liver cells.

10 xed population of wild-type and heterozygous fetal liver cells.

11 hat stem cells reside among CD4+ CD34++ Lin- fetal liver cells.

12 Kit(W-v) mice were reconstituted with normal fetal liver cells.

13 s of gestation with 1 x 10(6) ACI (RTla) rat fetal liver cells.

14 lerance induction in utero using donorstrain fetal liver cells.

15 at skin and cardiac tissue with donor-strain fetal liver cells.

16 angiopathies by exploring their functions in fetal liver cells.

17 enes genome-wide in embryonic stem cells and fetal liver cells.

18 munodeficient mice in the presence of scurfy fetal liver cells.

19 l hematopoiesis in transduced primary murine fetal liver cells.

20 that received a transplant of Stat5a/b(-/-) fetal liver cells.

21 mice that received a transplant of Cited2-/- fetal liver cells.

22 le concerning liver repopulation by Thy-1(+) fetal liver cells.

23 y stem cell transplantation using Stat5(-/-) fetal liver cells.

24 ying wild-type Sh3bp2 alleles through mutant fetal liver cells.

25 e reconstituted with ADAM17(DeltaZn/DeltaZn) fetal liver cells.

26 s from mouse bone marrow as well as in mouse fetal liver cells.

27 ferentiation in wild-type and JAK2-deficient fetal liver cells.

28 han either ankyrin or beta-spectrin in mouse fetal liver cells.

29 ce generated from normal and TRAF6-deficient fetal liver cells.

30 rorsine-treated liver, transplanted Thy-1(+) fetal liver cells achieved a 4.6%-23.5% repopulation.

31 Consistently, KLF4 can rescue PU.1-/- fetal liver cells along the monocytic lineage and can ac

32 Furthermore, all CD4+ CD34++ Lin- fetal liver cells also expressed CD13 and CD33.

33 Mutant fetal liver cells also fail to radioprotect lethally irr

34 CD34+ cells were enriched from human fetal liver cells and cocultivated with cell lines trans

35 ) mice reconstituted with NF-kappa Bp65(-/-) fetal liver cells and in c-Rel(-/-) mice.

36 Interestingly, both donor-strain fetal liver cells and neonatal skin grafts were required

37 /-) mice with a mixture of p50(-/-)/p65(-/-) fetal liver cells and Rag-2(-/-) bone marrow cells revea

38 efficiently rescue Gmcsf mutant recipients, fetal liver cells and Sca1(+) lin(-/dim) marrow cells ar

39 on and differentiation of yolk sac cells and fetal liver cells and stimulates directly hematopoietic

40 marrow stem cells would engraft similarly to fetal liver cells and that postnatal administration of c

41 ed expression of HAI-1 and -2 transcripts in fetal liver cells and this induction could be antagonize

42 oviral complementation of STAT5ab(null/null) fetal liver cells and transplantation, persistently acti

43 macrophage-specific markers CD 11b, F4/80 in fetal liver cells, and bone marrow-derived macrophages w

44 14), LPL(+/-) (n = 13), or LPL(+/+) (n = 14) fetal liver cells, and fed the Western diet for 19 weeks

45 mice, thymectomized mice reconstituted with fetal liver cells, and thymus-grafted mice, we provide d

46 with LPL(-/-) (n = 12) or LPL(+/+) (n = 14) fetal liver cells as a source of hematopoietic cells.

47 d expression of all B lineage genes in B220+ fetal liver cells as well as with a block in the transit

48 Mutant fetal liver cells behaved normally in in vitro hematopoi

49 In EBF- or EBF/Pax5-deficient fetal liver cells, both EBF and Pax5 were required for e

50 ines, on activated endothelial cells, and on fetal liver cells, but on few other cell types.

51 We have previously shown that MHC-mismatched fetal liver cells can durably engraft in 45% of nondefec

52 Thus, fetal liver cells can survive, proliferate, differentiat

53 CD133 defines a population of human fetal liver cells capable of differentiating into both a

54 Lack of STAT5 in fetal liver cells caused rapid differentiation and loss

55 MPD), and adoptive transfer of Nf1-deficient fetal liver cells consistently induces this MPD.

56 Fetal liver cells deficient for both NF-E2 and Nrf-2 exp

57 al upregulation of NF-E2 or Nrf-2 protein in fetal liver cells deficient for either factor.

58 id differentiation assay from primary murine fetal liver cells demonstrated that Elf-1 downregulation

59 rsist when Runx1 is conditionally deleted in fetal liver cells, demonstrating that the requirement fo

60 Fetal liver cells derived from low-density-lipoprotein r

61 tes with endogenous HOXB6 in day 14.5 murine fetal liver cells during active globin gene expression i

62 All mice transplanted with fetal liver cells ectopically expressing miR-125b showed

63 globin gene expression in primary erythroid fetal liver cells (eFLCs) after 72 hours in culture, fro

64 leukemic pathology in mice transplanted with fetal liver cells expressing translocated in liposarcoma

65 rprisingly, bcr/abl-expressing C/EBPalpha-/- fetal liver cells failed to induce a myeloid disease in

66 genitor cells, because Vav-iCre Ripk1(fl/fl) fetal liver cells failed to reconstitute hematopoiesis i

67 Using Mll(WT/WT) fetal liver cells (FLC) as baseline, we compared Mll(PTD

68 ted detectable Ram-1 in murine hematopoietic fetal liver cells (FLC) despite resistance of these cell

69 In K-ras(-/-) fetal liver cells (FLC), erythropoietin- or stem cell fa

70 e marrow transplantations of Fv-null (Fv-/-) fetal liver cells (FLCs) into wild-type mice.

71 transplantation of C57BL/6 mice with LPL-/- fetal liver cells (FLCs) was used to investigate the phy

72 ture hepatocytes in adult liver (adult HCs), fetal liver cells (FLCs), induced hepatic stem cells (iH

73 Fetal liver cells from Cited2 null embryos give rise to

74 Fetal liver cells from Cited2-/- embryos gave rise to ma

75 he K(b) and D(b) genes were repopulated with fetal liver cells from class I(+) TCR transgenic mice.

76 Fetal liver cells from Dusp16tp/tp embryos efficiently r

77 Mouse fetal liver cells from gestational day 17 possessed inte

78 of membrane-targeted or cytoplasmic Mpl into fetal liver cells from homozygous JAK2 knock-out mice or

79 Fetal liver cells from Lsh-/- were used as a source of h

80 study, we show that the bone marrow (BM) or fetal liver cells from LTalpha(-/-) or LTbetaR(-/-) mice

81 ally in thymocytes but was normal on B220(+) fetal liver cells from mouse embryos with diminished exp

82 Adoptive transfer of fetal liver cells from Nf1 mutant mice models JMML; howe

83 Fetal liver cells from NF90 gene-targeted mice were tran

84 Fetal liver cells from PDGF-B-deficient embryos were use

85 Fetal liver cells from TRAF3-deficient embryos can recon

86 Neither adult bone marrow-derived cells nor fetal liver cells from wild-type or Rag1-/- mice were ab

87 lly irradiated C57BL/6 mice with mixtures of fetal liver cells from WT and CD18-deficient mice.

88 every 8.9 Thy(low)Sca-1(+)lineage(-)Mac-1(+) fetal liver cells gave long-term multilineage reconstitu

89 .7 CD150(+)CD48(-)Sca-1(+)lineage(-)Mac-1(+) fetal liver cells gave long-term multilineage reconstitu

90 In this study, donor fetal liver cells had a 10-fold competitive engraftment

91 Mice reconstituted with CXCR4-deficient fetal liver cells have reduced donor-derived mature B ly

92 ing following HCV infection of primary human fetal liver cell (HFLC) cultures from 18 different donor

93 e demonstrate that primary cultures of human fetal liver cells (HFLC) reliably support infection with

94 an inflammatory cytokine expressed by human fetal liver cells (HFLCs) after infection with cell cult

95 Murine fetal liver cells, highly enriched in primitive progenit

96 41(lo/-) cells isolated from bone marrow and fetal liver cells, however, activity is enriched in the

97 marrow cells engrafted slightly better than fetal liver cells in allogeneic adult SCID transplant re

98 ion of human fetal thymic tissue and CD34(+) fetal liver cells in nonobese diabetic (NOD)/severe comb

99 topoietic reconstitution with Mafb-deficient fetal liver cells in recipient LDL receptor-deficient hy

100 sible causes, the colony-forming activity of fetal liver cells in vitro was assessed, and hematopoiet

101 oprecipitates with GATA-1 and EKLF in murine fetal liver cells in vivo and is recruited to the far-up

102 olony formation when expressed in (Epo-R)-/- fetal liver cells, indicating that Y464 either cannot se

103 human fetal thymus/liver tissues and CD34(+) fetal liver cells into immunodeficient nonobese diabetic

104 We transplanted uniparental fetal liver cells into lethally irradiated adult mice to

105 Transplantation of Bv8 null fetal liver cells into lethally irradiated hosts also re

106 Introduction of p50/p65-deficient fetal liver cells into lethally irradiated hosts resulte

107 emonstrated by the transplantation of mutant fetal liver cells into lethally irradiated recipients.

108 e present study, we transplanted necdin-null fetal liver cells into lethally irradiated recipients.

109 n fetal thymus and liver tissues and CD34(+) fetal liver cells into nonobese diabetic/severe combined

110 hematopoietic lineage, we transplanted Rb-/- fetal liver cells into sibling mice and assessed the out

111 s" generated by transplantation of KLF4(-/-) fetal livers cells into lethally irradiated wild-type mi

112 In addition, fetal liver cells lacking WT1 have an approximately 75%

113 The expression of bcr/abl in C/EBPalphapos fetal liver cells led to a chronic myeloid leukemia-like

114 , stem cell factor (SCF), FLT-3L, and murine fetal liver cell line (EL08.1D2), we identified 2 nonove

115 In primary culture of fetal liver cells, Lnk overexpression inhibits Epo-depen

116 Furthermore, we observe that in PU.1(-/-) fetal liver cells, low levels of the IE GATA-1 isoform i

117 re class I+ mice reconstituted with the same fetal liver cell mixture.

118 (WT) mice were reconstituted with either WT fetal liver cells or CD18-deficient fetal liver cells, o

119 also interfered with the differentiation of fetal liver cells or fetal thymocytes within deoxyguanos

120 ither WT fetal liver cells or CD18-deficient fetal liver cells, or an equal mixture of both types of

121 eric mice reconstituted with CXCR4-deficient fetal liver cells, plasma cells are mislocalized in the

122 ietic stem cells, a major component in crude fetal liver cell preparations that engraft in other orga

123 We hypothesized that unidentified fetal liver cells produce growth factors that support HS

124 Highly enriched Thy-1(+) ED14 fetal liver cells proliferate and repopulate the liver o

125 Transplanted ED 14 fetal liver cells proliferated continuously for 6 months

126 Previously we showed that the ~2% of fetal liver cells reactive with an anti-CD3epsilon monoc

127 ent ratios of fetal and adult cell mixtures, fetal liver cells repopulated 8.2 times better than adul

128 Rce1(-/-) fetal liver cells rescued lethally irradiated recipients

129 itution of p110gammadelta-/- animals with WT fetal liver cells restored the proportions of all thymoc

130 Fetal liver cells selected for Thy-1 expression using im

131 h PDGF-B(-/-), PDGFR beta(-/-), or wild-type fetal liver cells show complete engraftment (greater tha

132 sed embryonic lethality, and Srsf2-deficient fetal liver cells showed significantly enhanced apoptosi

133 In vitro culture of fetal-liver cells showed fewer hematopoietic progenitors

134 In contrast, Thy-1(-) fetal liver cells substantially repopulated normal adult

135 grafted with beta-globin-null (Hbb(th3/th3)) fetal liver cells succumb to ineffective erythropoiesis

136 ell lines and retrovirally transduced murine fetal liver cells suggest that most of these factors and

137 that had received both CD18-deficient and WT fetal liver cells, suggesting that myeloid hyperplasia w

138 r hematopoietic abnormalities in Klotho(-/-) fetal liver cells, suggesting that the effects of klotho

139 They are also the principal fetal liver cells that express CXCL12, a factor required

140 These are the principal fetal liver cells that express not only angiopoietin-lik

141 novel population of CD3+ and Ter119- day-15 fetal liver cells that support HSC expansion in culture,

142 h mixtures of class I+ and class I-deficient fetal liver cells, the rejection of class I-deficient bo

143 chimeras reconstituted with TRAF6-deficient fetal liver cells to analyze functions of TRAF6 in vivo

144 Bone marrow transplantation of SENP1 KO fetal liver cells to irradiated adult recipients confers

145 Exposure of fetal liver cells to rhGM-CSF for 1 to 3 days before add

146 acrophage cyclooxygenase-2 were generated by fetal liver cell transplantation and developed significa

147 Fetal liver cell transplantation studies revealed a 30%

148 Fetal liver cell transplantation was used to generate LD

149 PI3K-/- PLCgamma2-/- fetal liver cells transplanted into B-cell null JAK3-/-

150 (SP) thymocyte clusters in Plxnd1-deficient fetal liver cell-transplanted mice.

151 CD133+ fetal liver cells ultimately may be used for therapeutic

152 ptidase IV [DPPIV(+)]) embryonic day (ED) 14 fetal liver cells underwent transplantation into DPPIV(-

153 ents, B-cell development from Pbx1-deficient fetal liver cells was also severely compromised, but not

154 hite cell compartment of SCID mice by mutant fetal liver cells was less complete than that observed w

155 chimeras reconstituted with TRAF6-deficient fetal liver cells, we show that proper DC maturation req

156 Bone marrow cells and, alternatively, fetal liver cells were cultured in media containing M-CS

157 When Sca-1+c-kit+ fetal liver cells were cultured in methylcellulose media

158 ed by the observations that CD4+ CD34++ Lin- fetal liver cells were enriched for CDw90+ (Thy-1), CD11

159 a mixture of class I-deficient and class I+ fetal liver cells were more tolerant to class I-deficien

160 ted with a 50:50 mixture of WT and Rac2(-/-) fetal liver cells were protected from neutrophilia, sugg

161 Murine fetal liver cells were separated into distinct erythroid

162 Class I- mice reconstituted with class I+ fetal liver cells were tolerant of class I-deficient cel

163 When murine fetal liver cells were transduced with either of the hum

164 Fetal liver cells were transplanted from DPPIV(+) F344 r

165 Wild-type ED12.5 murine fetal liver cells were transplanted into adult dipeptidy

166 were 275-fold higher, compared with unsorted fetal liver cells, when 3 reprogramming factors were tra

167 oth murine erythroleukemia cells, as well as fetal liver cells, whereas an increase in PIAS3 levels i

168 DL-receptor deficient mice transplanted with fetal liver cells wildtype for cyclooxygenase-2, providi

169 Of 49 recipients of bone marrow or fetal liver cells with no evidence of donor cells in the

170 lymphocytes (IEL) developed efficiently from fetal liver cells, with a predominance of TCR alphabeta