ライフサイエンスコーパス: fibrillar

1 embrane vesicle-like structures and were not fibrillar.

2 antaneous increase in photoluminescence with fibrillar Abeta (primary light-switching), and an unprec

3 SF Abeta regularly becomes abnormal prior to fibrillar Abeta accumulation early in the course of dise

4 t attenuated accumulation of or clearance of fibrillar Abeta accumulation in randomized clinical tria

5 PSEN1(Deltaexon9) in neurons and accumulates fibrillar Abeta amyloid and amyloid plaques accompanied

6 e observed on amyloid plaque load or soluble fibrillar Abeta by quantitative immunohistochemical anal

7 0 levels and increased thioflavin S-positive fibrillar Abeta deposition.

8 zwitterionic lipids known to associate with fibrillar Abeta in lipid membranes and to be exposed on

9 significantly greater power to detect 24-mo fibrillar Abeta increases and evaluate Abeta-modifying t

10 riability; their power to track longitudinal fibrillar Abeta increases in Abeta+ and Abeta- subgroups

11 al trials; and their ability to relate 24-mo fibrillar Abeta increases to clinical declines.

12 may improve the power to track longitudinal fibrillar Abeta increases, to characterize their relatio

13 The transition from monomeric to fibrillar Abeta is of interest in the study of Alzheimer

14 Soluble Abeta1-42 and fibrillar Abeta measured by [(3)H] Pittsburgh compound-B

15 This suggests that non-fibrillar Abeta or early stage plaque depostion might in

16 compared with wild-type mice despite robust fibrillar Abeta plaque deposition.

17 magnetite nanostructures directly bound into fibrillar Abeta showed characteristic superparamagnetic

18 sion tomography was performed to investigate fibrillar Abeta, astrocytosis and cerebral glucose metab

19 ral metabolism and Pittsburgh compound B for fibrillar Abeta.

20 Furthermore, this peptide bound fibrillar Abeta42 and also stained plaques ex vivo in br

21 k techniques and allows the concentration of fibrillar Abeta42 propagons to be detected and quantifie

22 letion favors NSC differentiation into glial fibrillar acidic protein (GFAP)-immunoreactive cells ove

23 The multifunctional fibrillar adhesin CshA, which mediates binding to both h

24 duction to regulate alpha5beta1-integrin and fibrillar adhesion assembly and thus reveal an important

25 ins, supporting their activity and promoting fibrillar adhesion formation and integrin-dependent proc

26 ctive beta1-integrin- and tensin-rich mature fibrillar adhesions, and cell spreading.

27 ctility, and promoted formation of focal and fibrillar adhesions.

28 deliver the role of spatulae, mimicking the fibrillar adhesive surfaces of geckos.

29 The adhesive characteristics of fibrillar adhesives on a soft deformable membrane are re

30 s mimicked by integration of film-terminated fibrillar adhesives to hybrid nematic liquid crystal net

31 , and curcumin, redirect Abeta(17-36) from a fibrillar aggregate to an unstructured oligomer.

32 ta1-40 aggregated into a variety of distinct fibrillar aggregates and disrupted the bilayer structure

33 is an intrinsically disordered protein whose fibrillar aggregates are the major constituents of Lewy

34 , mechanical and morphological properties of fibrillar aggregates at the single molecule and nanomete

35 The formation of fibrillar aggregates has long been associated with neuro

36 ta suggest participation by both soluble and fibrillar aggregates in IAPP-induced islet inflammation.

37 endritic compartment (6) and accumulation of fibrillar aggregates in NFTs mediates neurodegeneration

38 The assembly of various proteins into fibrillar aggregates is an important phenomenon with wid

39 ta2m and their subsequent progression toward fibrillar aggregates is of great importance.

40 l symptoms by several years, imaging of such fibrillar aggregates is particularly suitable to diagnos

41 Fibrillar aggregates of Abeta and Tau in the brain are t

42 mography (SPT) we characterize the growth of fibrillar aggregates of mutant huntingtin exon 1 contain

43 Fibrillar aggregates possessing distinct structures that

44 ontaneous in vitro formation of amyloid-like fibrillar aggregates was observed in mutant but not wild

45 ke microstructures, Ac-LVE and Ac-YYD formed fibrillar aggregates, Ac-VIE and Ac-MYD formed hydrogels

46 ed at the core of the superoxide dismutase-1 fibrillar aggregates, beta-barrel loop II-strand 3, rath

47 e monomer and the hairpin assembles into non-fibrillar aggregates, demonstrating that the hairpin fol

48 s misfold and self assemble into soluble pre-fibrillar aggregates, i.e., protofibrils, which elongate

49 However, besides the fact that it forms fibrillar aggregates, structural information of Orb2 is

50 beta self-assembles into parallel cross-beta fibrillar aggregates, which is associated with Alzheimer

51 amino acid known to self-assemble into toxic fibrillar aggregates.

52 Amyloids are insoluble protein fibrillar aggregates.

53 e case for thioflavin T fluorescence for the fibrillar aggregates.

54 ted on mica, predominately forming extended, fibrillar aggregates.

55 ls, which elongate and mature into insoluble fibrillar aggregates.

56 nsitions of monomers-paranuclei-protofibrils-fibrillar aggregates.

57 s a disease that affects vital organs by the fibrillar aggregation of monoclonal light chains.

58 e the arrest of aggregation in an early, non-fibrillar aggregation stage.

59 also rescues proteins from irreversible non-fibrillar aggregation.

60 a and tau fibrils is not optimal for imaging fibrillar alpha-syn in vivo, but we show that SIL23 comp

61 We hypothesized that injection of fibrillar alpha-syn into the OB of wild-type mice would

62 resence of Lewy body inclusions comprised of fibrillar alpha-syn within affected regions of PD brain

63 ates (but not monomeric, small oligomeric or fibrillar alpha-synuclein aggregates) exhibit the inhibi

64 ta42 (the 42-residue form of Abeta) fibrils, fibrillar alpha-synuclein catalyses the heterogeneous nu

65 between the concentrations of monomeric and fibrillar alpha-synuclein that determines the outcome of

66 nic mice showed abundant oligomeric, but not fibrillar, alpha-synuclein whereas lower-expressing mice

67 Fibrillar alphaS is taken up by pMac by actin-rearrangem

68 lar alphaSyn oligomers, but not monomeric or fibrillar alphaSyn, decreased the retention time of exog

69 Although fibrillar amyloid beta (Abeta)-stimulated cytokine secre

70 Thus we conclude that regional fibrillar amyloid deposition has little to no associatio

71 ifically associated with Abeta oligomers, as fibrillar amyloid deposits were not detected in oligomer

72 aggregates, including soluble oligomers and fibrillar amyloid deposits, which are linked with neurod

73 l impairment, but never develops parenchymal fibrillar amyloid deposits.

74 d with an elevated accumulation of Abeta and fibrillar amyloid in the brain compared with either sing

75 lial activation and its relationship between fibrillar amyloid load at baseline and follow-up in subj

76 hich was associated with a mild elevation in fibrillar amyloid load.

77 midlife BMI was also associated with greater fibrillar amyloid measured by global mean cortical distr

78 cumulation of neuritic amyloid pathology and fibrillar amyloid on in vivo imaging, and increased numb

79 ogenic rodent IAPP and thioflavin-T-positive fibrillar amyloid produced by human IAPP aggregation fai

80 and reflects the structural polymorphisms in fibrillar amyloid structures.

81 iated with Alzheimer's disease (AD) comprise fibrillar amyloid-beta (Abeta) peptides as well as non-p

82 on of specific functional networks, and that fibrillar amyloid-beta deposition explains at most a sma

83 lity of macrophages to phagocytose preformed fibrillar amyloid-beta1-42 (P < 0.0001).

84 y and enzymatically oxidized apoA-I produced fibrillar amyloids after a few hours of incubation.

85 Fibrillar and nonfibrillar components of ECM can limit a

86 concentrated collagen sample in its soluble, fibrillar, and denatured states using one and two dimens

87 During contact guidance, the fibrillar architecture of the ECM promotes an elongated

88 ns of 3 form floret-shaped constructs, while fibrillar architectures are formed in water.

89 e biomechanical characteristics and regional fibrillar arrangement of porcine RDT.

90 We propose the fibrillar arrangement of the NSs core domain in crystals

91 Finally, we show that fibrillar aS loses almost 80% of its scavenging activity

92 the C-terminus in the complete maturation of fibrillar aS.

93 s with shape-memory properties, and that the fibrillar assemblies can be actuated on application of a

94 suggesting that it promotes the formation of fibrillar assemblies.

95 oid-beta (Abeta) peptide into oligomeric and fibrillar assemblies; however, little is known about the

96 The fibrillar assembly and deposition of amyloid beta (Abeta

97 mer-peptide conjugates (mPPCs) that redirect fibrillar assembly of Abeta to form discrete nanostructu

98 Taking fibrillar assembly of amyloid beta (Abeta) peptide as th

99 Taking a fibrillar assembly of amyloid beta (Abeta) peptide as th

100 with postmortem beta-amyloid load as well as fibrillar beta-amyloid in 2 independent cohorts of adult

101 by immunocytochemistry, and replication with fibrillar beta-amyloid positron emission tomographic ima

102 It is increasingly recognized that small non-fibrillar beta-sheet-rich oligomers of PrP may be of cru

103 Fibrillar beta2-microglobulin is resistant to lysosomal

104 verity of Alzheimer's neuropathology and (3) fibrillar brain amyloid deposition during aging.

105 n that these two organelles are connected by fibrillar bridges and that their close physical contact

106 the microtubule associated tau protein into fibrillar cell inclusions is linked to a number of devas

107 ms that govern the formation and assembly of fibrillar cellulosic structures and cell wall composites

108 hesis by SoxE and SoxD regulation of clade A fibrillar collagen (ColA) genes--suggesting that the cho

109 We report that a novel high-density fibrillar collagen (HDFC) matrix is a potent inducer of

110 es depend on changes in extracellular matrix fibrillar collagen and cardiomyocyte titin.

111 efficient induction of invadopodia on dense fibrillar collagen and for local degradation of collagen

112 nization, including density and alignment of fibrillar collagen and myofibroblasts.

113 al in vivo degradation of the self-assembled fibrillar collagen and the majority of implants experien

114 50 Pa and increased to 1-6 kPa in areas near fibrillar collagen deposition in fibrotic livers.

115 Fibrillar collagen expression and content were increased

116 s in mouse (termed SMKO) resulted in altered fibrillar collagen localization with larger, poorly orga

117 -) fibroblasts lost their ability to process fibrillar collagen type I and to activate proMMP-2.

118 usceptibility to CatK-mediated hydrolysis of fibrillar collagen was observed following mineralization

119 h encodes the alpha chain of an atypical non-fibrillar collagen with a single transmembrane domain.

120 Mineralization of fibrillar collagen with biomimetic process-directing age

121 Fibrillar collagen, an essential structural component of

122 iological stimulus for MT1-MMP expression is fibrillar collagen, and it has been shown that it up-reg

123 Cre tumors was enriched with stromal-derived fibrillar collagen, compared with wild-type or Hras-driv

124 anism for tension-dependent stabilization of fibrillar collagen.

125 lation may regulate cross-link maturation in fibrillar collagen.

126 r thermal stability is comparable to that of fibrillar collagen.

127 le blood over a 250-mum long patch of type I fibrillar collagen/lipidated tissue factor (TF; approxim

128 An increase in fibrillar collagens 1 and 5 was detected.

129 Fibrillar collagens are present in a wide variety of ani

130 The mechanical strength of fibrillar collagens is highly dependent on the formation

131 oinformatic analysis provides insight on how fibrillar collagens might have arisen from the duplicati

132 exhibited higher stiffness and expression of fibrillar collagens than control fibroblasts, concomitan

133 ts and enhanced expression and deposition of fibrillar collagens) increased progressively.

134 include MMP-1, which preferentially degrades fibrillar collagens, and MMP-3, which can initiate a loc

135 mong other requirements, cross-links between fibrillar collagens, introduced by tissue transglutamina

136 oid potential immunogenicity associated with fibrillar collagens, were fabricated with and without ch

137 on of lysine residues in the telopeptides of fibrillar collagens, which leads to the formation of sta

138 he cross-striated banding pattern typical of fibrillar collagens.

139 expression of EMT/myofibroblast markers and fibrillar collagens.

140 ed to the formation and further expansion of fibrillar collagens.

141 resent in 90S and was localized in the dense fibrillar component of the nucleolus dependently on acti

142 by immuno dot blot assays for oligomeric and fibrillar components.

143 ves the assembly of medin by stabilizing the fibrillar conformation of the peptide and is thus remini

144 ce of a structurally related family of quasi-fibrillar conformers of Abeta42, which is stabilized bot

145 assembly of plasmonic nanoparticles onto the fibrillar constructs.

146 Fibrillar contents within the spherules were also recons

147 duced by the variant only after its complete fibrillar conversion.

148 though the two termini are excluded from the fibrillar core, they are engaged in a number of intermol

149 nsically disordered monomeric state into the fibrillar cross-beta aggregates characteristically prese

150 ferent proteins assemble into highly ordered fibrillar deposits and cause disease remain topics of de

151 aggregation of amyloid into cross-beta-sheet fibrillar deposits by mechanisms not fully understood.

152 Amyloid beta (Abeta) fibrillar deposits in the brain are a hallmark of Alzhei

153 hypothesis of Alzheimer's disease holds that fibrillar deposits of amyloid are an early, driving forc

154 ic protein that forms abundant extracellular fibrillar deposits.

155 lly strong nanofiber skeleton with a lateral fibrillar diameter of a few nanometers.

156 sitive in both sexes, indicative of the less fibrillar (diffuse) nature of Abeta plaques in gorillas.

157 We propose the characteristic fibrillar dimension (CFD) at which effective sliding is

158 lerated almost threefold to 0.68 mum/min and fibrillar dimensions were increased, underlining the imp

159 pattern linear fibronectin features to mimic fibrillar ECM and elucidate the mechanisms of contact gu

160 mosomes via the engagement of integrins with fibrillar ECM proteins.

161 tic hits interact to change cell behavior in fibrillar environments.

162 Magic-angle-spinning NMR reveals that fibrillar exon1 has a partly mobile alpha-helix in its a

163 membrane retractions, indicating a stepwise fibrillar extension mechanism.

164 membrane retractions, indicating a stepwise fibrillar extension mechanism.

165 t is directly linked to strong deposition of fibrillar extracellular matrix (ECM) components and high

166 myofibroblasts to assemble exogenous FN into fibrillar extracellular matrix.

167 Thus, dorsal SFs and fibrillar FAs form a specific class of integrated adhesi

168 gation and maturation into tensin-containing fibrillar FAs in the cell center.

169 he formin INF2 in specifying the function of fibrillar FAs through its ability to generate dorsal SFs

170 ro by investigating LTBP-1 organisation with fibrillar fibronectin and show that all trans-retinoic a

171 RPK sequence in the first type III repeat of fibrillar fibronectin.

172 to amyloid structures while MHP1 forms a non-fibrillar film.

173 nding region of the first type III repeat of fibrillar FN (FNIII1H) mediates vasodilatation, and (ii)

174 w that migration of carcinoma collectives on fibrillar FN-rich matrices is achieved through alphavbet

175 ly disordered monomeric form to a cross-beta fibrillar form.

176 40 surface, potentially related to a role in fibrillar formation.

177 oretic behavior of monomeric, oligomeric and fibrillar forms of alpha-synuclein.

178 entified that bind monomeric, oligomeric, or fibrillar forms of amyloid-beta (Abeta).

179 Growing evidence suggests water-soluble, non-fibrillar forms of amyloid-beta protein (Abeta) have imp

180 orming ability of monomeric, oligomeric, and fibrillar forms of both Abeta(1-40) and Abeta(1-42).

181 for interconversion between prefibrillar and fibrillar forms to identify a conversion pathway between

182 cularly when they are in their oligomeric or fibrillar forms.

183 n have also been observed, likely indicating fibrillar fusion events.

184 ic binding of cathepsin K at the edge of the fibrillar gap region of collagen fibers, which suggest i

185 ules and culminates in formation of a dense, fibrillar-globular coat over microtubule bundles.

186 e kinetics of oligomerization and subsequent fibrillar growth by allowing the conformational changes

187 nalization is in agreement with the measured fibrillar growth of alpha-synuclein from Parkinson and a

188 Inhibiting formation of these fibrillar hydrogel assemblies mitigates neurotoxicity an

189 further phase transition into poorly soluble fibrillar hydrogels distinct from conventional amyloids.

190 BMDMs treated with soluble but not fibrillar IAPP provided a TLR2-dependent priming stimulu

191 mple columnar epithelium, SEVI was no longer fibrillar in structure and was detached from virions but

192 ation of these bigenic mice, the severity of fibrillar inclusion pathology was diminished and unreact

193 f soluble alpha-synuclein into insoluble and fibrillar inclusions is a hallmark of Parkinson's diseas

194 einopathy-diseases that are characterized by fibrillar inclusions of RBPs.

195 of this new model showed SOD1 immunoreactive fibrillar inclusions.

196 In the adult Drosophila musculature, the fibrillar indirect flight muscles accumulate a >200 kDa

197 quantified by d-AQuA was similar to that of fibrillar insulin aggregates detected by atomic-force mi

198 expression does not trigger the formation of fibrillar LB-like inclusions in mice.

199 Amyloid beta and tau form fibrillar lesions that are the classical hallmarks of AD

200 Our results show the importance of fibrillar links in tethering microtubule ends to cargo:

201 ining has a distinct effect on the growth of fibrillar mass density (which can be measured experiment

202 Interestingly, the hybrid wild-type/variant fibrillar material acquired a thermodynamic stability si

203 tructural and mechanical properties of these fibrillar matrices depend on the conditions under which

204 hich cells probe and respond to mechanics in fibrillar matrices.

205 ocontractile culture conditions, fibronectin fibrillar matrix assembly by human fibroblasts functione

206 blasts assemble exogenous FN (488-FN) into a fibrillar matrix more rapidly than fibroblasts that have

207 into how genetic perturbations conspire with fibrillar maturation in the TMEN to drive the invasive b

208 oximately 26% of the maximum adhesion of the fibrillar membrane, which is 14x higher than the adherin

209 ing directs the assembly of Sup35NM into non-fibrillar, membrane-bound aggregates that resemble PrPSc

210 cted hosts, PrPSc usually accumulates as non-fibrillar, membrane-bound aggregates.

211 icroscopy to probe structural differences in fibrillar models of the ovarian stroma comprised of mixt

212 esults will enable experimentalists to infer fibrillar morphologies from an appropriate analysis of s

213 form of 3D texture analysis to delineate the fibrillar morphology observed in 3D Second Harmonic Gene

214 Ammonium-functionalized fibrillar nanocarbon is found to preferentially localize

215 of chiral amide groups in the formation of a fibrillar nanomaterial.

216 core-shell morphology such as spherical and fibrillar nanostructures could be controlled by adjustin

217 in that can be assembled by cells into large fibrillar networks, but the dynamics of FN remodeling an

218 in that can be assembled by cells into large fibrillar networks, but the dynamics of FN remodeling an

219 molecular gelators into their self-assembled fibrillar networks.

220 The fibrillar oligomer only becomes favored over its prefibr

221 uggest that increased propensity to form non-fibrillar oligomers is the shared property of these fami

222 nsist of mainly antiparallel beta-sheets and fibrillar oligomers with only parallel beta-sheets.

223 decreasing formation of visible inclusions, fibrillar oligomers, and insoluble mHtt derived from exp

224 Gremlin-1 but a pronounced effect on matrix fibrillar organisation was revealed.

225 anogold affinity tags in the context of wall fibrillar organization.

226 y increases with increasing concentration of fibrillar over monomeric Abeta forms, and that Abeta-ind

227 on of cellulose in the open state and a more fibrillar pattern in the closed state, indicating that c

228 results were grade 1, normal, with parallel fibrillar pattern; grade 2, mild tendinopathy, with cell

229 d as grade 1, normal tendon with homogeneous fibrillar pattern; grade 2, tendon thickening or hypoech

230 ween the pre-fibrillar tetramer form and the fibrillar pentamer in the Abeta40 aggregation landscape

231 rlier manifestation of neuritic plaques) and fibrillar plaques in Alzheimer's disease (AD) brain sect

232 g high-aspect ratio micropatterns as a model fibrillar platform, we show that metastatic cells overco

233 ly expressed pre-melanosomal markers OA1 and fibrillar PMEL, following early endosomal sorting by the

234 ood and may include both inhibition of Abeta fibrillar polymerization and direct depolymerization of

235 ecedence over surface catalysis and leads to fibrillar polymorphism.

236 Accumulation of fibrillar protein aggregates is a hallmark of many disea

237 metry, which are efficient inhibitors of non-fibrillar protein aggregation.

238 Mimicking the multistep self-assembly of the fibrillar protein collagen is an important design challe

239 teins that can cause systemic amyloidosis, a fibrillar protein deposition disease that leads to end-o

240 link between persistent stress granules and fibrillar protein pathology in disease.

241 and compared to native protein, early-stage-fibrillar protein, and sonicated fibrils in two immortal

242 The extracellular matrix (ECM) is a fibrillar protein-based network, the physical and chemic

243 eins and globular were more susceptible than fibrillar proteins.

244 erved positions, and is reminiscent of other fibrillar proteins.

245 A model of stiffness modulation via enhanced fibrillar recruitment is developed to explain the biophy

246 bic drug (dexamethasone (Dex)) within beaded fibrillar scaffold of poly(ethylene oxide terephthalate)

247 that hMSCs cultured on Dex containing beaded fibrillar scaffolds exhibit an increase in osteogenic di

248 ned drug release that is integrated into the fibrillar scaffolds.

249 e in endosomal compartments, where they form fibrillar seeds that subsequently induce the aggregation

250 based on parallel in-register architectures, fibrillar shapes and dimensions, and other available exp

251 propensity by defining the size and shape of fibrillar SOD aggregates after mild biochemical perturba

252 al polypeptides, of any sense, form compact, fibrillar solids with a beta-sheet structure.

253 Non-fibrillar soluble oligomeric forms of amyloid-beta pepti

254 individually characterize the oligomeric and fibrillar species formed along the amyloid aggregation.

255 region of Abeta contributes to the enhanced fibrillar stability due to a gain of function mechanism

256 ling and the transition through intermediate fibrillar stages are incompletely understood.

257 ling and the transition through intermediate fibrillar stages are still incompletely understood.

258 The globular native fold transition to the fibrillar state is primed by exposure to a hydrophobic-h

259 n which Abeta converts from a monomeric to a fibrillar state via a series of kinetically defined step

260 regions that form the beta-sheet core in the fibrillar state, although their spatial arrangement may

261 In the fibrillar state, use of circular dichroism, atomic-force

262 de novo designed gel-forming peptide, in its fibrillar state.

263 that lead to the formation of oligomeric and fibrillar states of amyloid-beta(1-42) (Abeta(1-42)) dur

264 induce drastic architectural changes in the fibrillar structure but intercalates between the two bet

265 n very small changes in the assumed material fibrillar structure can produce large changes in the wav

266 ffraction to probe time-dependent changes in fibrillar structure during in situ tensile testing of se

267 in individual plaques there is a gradient of fibrillar structure from core to margins.

268 y manipulating this pathway, we show that BM fibrillar structure influences egg chamber morphogenesis

269 otivates attempts to better understand their fibrillar structure.

270 phology and other physical properties of the fibrillar structure.

271 nalysis of native Sup35 reveals that similar fibrillar structures are formed in both the wild-type an

272 However, all fibrillar structures formed possess an unexpected right-

273 minal residues 138-144 prevents formation of fibrillar structures in agreement with the experiment.

274 by solid-phase peptide synthesis, also forms fibrillar structures in water at pH 2.

275 Self-assembly of proteins into ordered, fibrillar structures is a commonly observed theme in bio

276 ational distributions in protein aggregates, fibrillar structures of cells, and cell membranes.

277 y demonstrates that MinE self-assembles into fibrillar structures on the supported lipid bilayer.

278 taining methods, we found that 5-15-mum-long fibrillar structures stained by anti-MSP3 antibodies wer

279 a monomers undergo structural transitions to fibrillar structures upon their binding to fibril tips.

280 electron microscopy of the fibrin gel showed fibrillar structures with a high degree of cross-linking

281 betaalphabeta fold that self-assembles into fibrillar structures.

282 d, amorphous aggregates as opposed to linear fibrillar structures.

283 from disordered monomers to beta-sheet-rich fibrillar structures.

284 histories may contain different ensembles of fibrillar structures; (ii) plaques harboring distinct am

285 stabilization, and enhances the formation of fibrillar tau aggregates, highlighting both loss and gai

286 INTERPRETATION: Biomarkers of fibrillar tau deposition can be included with those of b

287 in mechanosensation occurs before detectable fibrillar tau formation.

288 However, fibrillar tau has been dissociated from neuron death and

289 he clear free energy barrier between the pre-fibrillar tetramer form and the fibrillar pentamer in th

290 the conversion from pre-fibrillar trimers to fibrillar tetramers.

291 ed cases had significantly higher burdens of fibrillar thioflavin-S-positive plaques and of oligomeri

292 more complex physiological and pathological fibrillar tissues organization.

293 tact response of migrating cancer cells in a fibrillar TMEN is poorly understood.

294 d greatly facilitate the conversion from pre-fibrillar trimers to fibrillar tetramers.

295 Fibrillar type I collagen is the major organic component

296 alpha2beta1 integrin in contact with dermal fibrillar type I collagen, and the activity of MMP-1 is

297 Fibrillar type I collagen-based hydrogels are commonly u

298 ow we used this method to image the collagen fibrillar ultrastructure of intact rat tail tendons.

299 , and thioflavin-S binding established their fibrillar ultrastructure, and fluorescence recovery afte

300 n notably for the tripeptide, which produced fibrillar xerogels.