ライフサイエンスコーパス: fibrinolytic system

1 n between two proteins of the complement and fibrinolytic system.

2 ne protease plasmin, a central enzyme of the fibrinolytic system.

3 but subsequently generates inhibitors of the fibrinolytic system.

4 and the functioning of the plasminogen-based fibrinolytic system.

5 capable of inducing other components of the fibrinolytic system.

6 lts from ordered breakdown of thrombi by the fibrinolytic system.

7 s, is considered a critical regulator of the fibrinolytic system.

8 PA suggested a decrease in inhibition of the fibrinolytic system.

9 rliest targets attacked by plasmin following fibrinolytic system activation.

10 brinogen, were released in vivo early during fibrinolytic system activation.

11 In conclusion, troglitazone enhances fibrinolytic system activity in insulin-resistant type 2

12 d by approximately 20%, indicating augmented fibrinolytic system activity.

13 I-1) is a major physiologic regulator of the fibrinolytic system and has recently gained recognition

14 ationships between protein components of the fibrinolytic system and infectivity by Mycobacterium avi

15 zed the effects of IL-1 on the expression of fibrinolytic system and matrix proteins in rat cardiac m

16 To examine the relationship between the fibrinolytic system and pulmonary fibrosis, lung inflamm

17 Additionally, the role of the coagulation/fibrinolytic systems and angiogenesis has also been exam

18 f endothelial activation, protein C pathway, fibrinolytic system, and complement.

19 coagulation and anticoagulant pathways, the fibrinolytic system, and platelets in the pathophysiolog

20 ment system, the blood clotting cascade, the fibrinolytic system, and the kallikrein-kinin system.

21 activation mechanisms of the coagulation and fibrinolytic systems, and therefore the prethrombotic st

22 Haemodynamic forces and the fibrinolytic system are considered to be the principal m

23 The complement, coagulation, and fibrinolytic systems are crucial for the maintenance of

24 These findings define the endogenous fibrinolytic system as an important regulator of clot re

25 ude components of complement and coagulation-fibrinolytic systems, as well as plasma lipoproteins.

26 Although the fibrinolytic system assembles at the site of pulmonary e

27 ion system is best known as an extracellular fibrinolytic system but was previously reported to also

28 d/or inhibition of natural anticoagulant and fibrinolytic systems by antiphospholipid antibodies.

29 These studies showed that the protein C and fibrinolytic systems can work in tandem to regulate even

30 The coagulation and fibrinolytic systems contribute to malignancy by increas

31 Our findings indicate that disruption of p53-fibrinolytic system cross talk may serve as a novel inte

32 Dysregulation of the fibrinolytic system developed during the course of infec

33 acids lower fibrinogen or interact with the fibrinolytic system directly.

34 Absence of these two components of the fibrinolytic system, either urokinase or plasminogen, re

35 Components of the fibrinolytic system have been implicated in cell migrato

36 lts of these studies indicate a role for the fibrinolytic system in acute lung injury and suggests th

37 plasma PAI-1 and relief of inhibition of the fibrinolytic system in elderly, obese subjects.

38 sults underscore the importance of the human fibrinolytic system in host-pathogen interactions in inv

39 Consistent with an important role of the fibrinolytic system in hypoxia-induced fibrin accumulati

40 ortant potential role of macrophages and the fibrinolytic system in ischemia-induced thrombosis.

41 tion and expression of the components of the fibrinolytic system in patients with chronic rhinosinusi

42 To determine the role of the fibrinolytic system in regulating the pathologies associ

43 this study emphasize the involvement of the fibrinolytic system in vascular repair processes after i

44 Fibrin is degraded by the fibrinolytic system in which a plasminogen activator con

45 e known to express several components of the fibrinolytic system, including PAI-1.

46 ducing expression of other components of the fibrinolytic system, including uPAR.

47 ity of uPA to induce other components of the fibrinolytic system, involves posttranscriptional regula

48 Because the fibrinolytic system is active during repair processes th

49 The fibrinolytic system is known to play an important role i

50 nd urokinase-dependent pathways by which the fibrinolytic system is regulated in the lung.

51 Although the fibrinolytic system is strongly affected by infection, t

52 fying the activity of a key regulator of the fibrinolytic system, like alpha2-antiplasmin, may have u

53 Thus, the fibrinolytic system linked by an activation cascade may

54 Because of the complexity of the fibrinolytic system, mathematical models closely tied wi

55 of disorders involving dysregulation of the fibrinolytic system may affect interactions between fibr

56 xaggerated activation of the coagulation and fibrinolytic systems may contribute to the clinically ob

57 effects of low ambient oxygen tension on the fibrinolytic system, mice were placed in a hypoxic envir

58 nsequently, modulation of the local cellular fibrinolytic system of catecholaminergic cells results i

59 ss the physiological impact of an imbalanced fibrinolytic system on both early and late stages of thi

60 assembly and activation of components of the fibrinolytic system on the abnormal fibrin, resulting in

61 lderly, obese individuals, and its effect on fibrinolytic system peptides was measured.

62 in III complexes), nor the activation of the fibrinolytic system (plasma levels of tissue-type plasmi

63 hrombin III complexes, and activation of the fibrinolytic system (plasma levels of tissue-type plasmi

64 elium (plasma von Willebrand levels) and the fibrinolytic system (plasma tissue-type plasminogen acti

65 Activation of the fibrinolytic system (plasminogen activator activity, tis

66 ionally activates the central zymogen of the fibrinolytic system, plasminogen (Pg).

67 sminogen axis provides cells with a powerful fibrinolytic system, plasminogen-deleted animals use alt

68 elial cells suggest that the coagulation and fibrinolytic systems play an important role in corneal w

69 The fibrinolytic system plays a key role in the regulation o

70 The results obtained suggest that the host fibrinolytic system plays an important role in tumor gro

71 ibitor-1 (PAI-1), a central regulator of the fibrinolytic system, plays an important role in determin

72 In addition, we observed altered airway fibrinolytic system protein balance consistent with prom

73 Despite abundant evidence for the fibrinolytic system regulating thrombosis, it has been o

74 cascades, such as the blood coagulation and fibrinolytic systems, required the evolution of protease

75 nd negative modulation of the local cellular fibrinolytic system resulted in substantial alterations

76 thesized that plasmin, the key enzyme of the fibrinolytic system, serves as a physiological backup en

77 In the fibrinolytic system, the serpin PAI-1 negatively regulat

78 However, if balanced by a healthy fibrinolytic system, thrombosis may not occur or cause l

79 o link the renin-angiotensin system with the fibrinolytic system to regulate trophoblast invasion.

80 No correlation was seen between fibrinolytic system variables and baseline concentration

81 gen and activity levels of components of the fibrinolytic system were measured by immunoassays, which