ライフサイエンスコーパス: fibroblast growth factor receptor 3

1 vascular endothelial growth factor (VEGF) or fibroblast growth factor receptor-3.

2 observed stimulation of VEGF receptor-1 and fibroblast growth factor receptor-3.

3 mulates further growth factor receptors like fibroblast growth factor receptor-3.

4 thelial cells, secretoneurin also stimulated fibroblast growth factor receptor-3 and insulin-like gro

5 E TM domain mutation on the stability of the fibroblast growth factor receptor 3 dimer in the presenc

6 these results to the case of the isolated TM fibroblast growth factor receptor 3 domains.

7 caused by gain-of-function mutations in the fibroblast growth factor receptor 3-encoding (FGFR3-enco

8 receptor, bone morphogenetic protein-7, and fibroblast growth factor receptor-3 expression increased

9 We have identified a role for fibroblast growth factor receptor 3 (FGFR-3) in this pro

10 Fibroblast growth factor receptor-3 (FGFR-3) expression

11 an autosomal-dominant activating mutation in fibroblast growth factor receptor 3 (FGFR3(P250R) ).

12 ice with the K644E kinase domain mutation in fibroblast growth factor receptor 3 (Fgfr3) (EIIa;Fgfr3(

13 have the same point mutation in the gene for fibroblast growth factor receptor 3 (FGFR3) and more tha

14 n that it involves 2 potential target genes: fibroblast growth factor receptor 3 (FGFR3) and multiple

15 Mutations to fibroblast growth factor receptor 3 (FGFR3) and phosphat

16 athymic nude mice, due to down regulation of fibroblast growth factor receptor 3 (FGFR3) and PI3K/Akt

17 Although activating mutations of fibroblast growth factor receptor 3 (FGFR3) are frequent

18 Mutations of fibroblast growth factor receptor 3 (FGFR3) are responsi

19 Ectopic expression of fibroblast growth factor receptor 3 (FGFR3) associated w

20 Fibroblast growth factor receptor 3 (FGFR3) belongs to a

21 have previously shown that dysregulation of fibroblast growth factor receptor 3 (FGFR3) by the t(4;1

22 Mutations in fibroblast growth factor receptor 3 (FGFR3) cause the mo

23 380R mutation in the transmembrane domain of fibroblast growth factor receptor 3 (FGFR3) causes achon

24 Fibroblast growth factor receptor 3 (FGFR3) coimmunoprec

25 ently reported that receptor tyrosine kinase fibroblast growth factor receptor 3 (FGFR3) directly tyr

26 quency of the nucleotide substitution in the fibroblast growth factor receptor 3 (FGFR3) gene that ca

27 of two mutations (G1138A and G1138C) in the fibroblast growth factor receptor 3 (FGFR3) gene, which

28 Fibroblast growth factor receptor 3 (FGFR3) has a comple

29 Recently, fibroblast growth factor receptor 3 (FGFR3) has also bee

30 e C749G (Pro250Arg) mutation in the gene for fibroblast growth factor receptor 3 (FGFR3) has been fou

31 erozygous mutations of the gene encoding the fibroblast growth factor receptor 3 (FGFR3) have been fo

32 ermline mutations of the gene encoding human fibroblast growth factor receptor 3 (FGFR3) have been sh

33 380R mutation in the transmembrane domain of fibroblast growth factor receptor 3 (FGFR3) in >97% of t

34 Fibroblast growth factor receptor 3 (FGFR3) influences a

35 We recently found that the fibroblast growth factor receptor 3 (FGFR3) interacts wi

36 Fibroblast growth factor receptor 3 (FGFR3) is a develop

37 Fibroblast growth factor receptor 3 (FGFR3) is a key reg

38 Fibroblast growth factor receptor 3 (FGFR3) is a key reg

39 Fibroblast growth factor receptor 3 (FGFR3) is a major n

40 Fibroblast growth factor receptor 3 (FGFR3) is a recepto

41 Fibroblast growth factor receptor 3 (Fgfr3) is a tyrosin

42 Ectopic activation of fibroblast growth factor receptor 3 (FGFR3) is associate

43 Fibroblast growth factor receptor 3 (FGFR3) is expressed

44 ly, we found that the enhanced activation of fibroblast growth factor receptor 3 (FGFR3) is linked to

45 The A391E mutation in fibroblast growth factor receptor 3 (FGFR3) is the genet

46 We have identified a novel fibroblast growth factor receptor 3 (FGFR3) missense mut

47 Fibroblast growth factor receptor 3 (FGFR3) mutations ar

48 Fibroblast growth factor receptor 3 (FGFR3) mutations ar

49 Missense mutations of fibroblast growth factor receptor 3 (FGFR3) occur in up

50 Gly380 --> Arg mutation in the TM domain of fibroblast growth factor receptor 3 (FGFR3) of the RTK f

51 Fibroblast growth factor receptor 3 (FGFR3) plays a crit

52 ysregulation of the receptor tyrosine kinase fibroblast growth factor receptor 3 (FGFR3) plays a path

53 Several studies suggest fibroblast growth factor receptor 3 (FGFR3) plays a role

54 Fibroblast growth factor receptor 3 (FGFR3) plays an imp

55 Missense mutations in fibroblast growth factor receptor 3 (FGFR3) result in se

56 Missense mutations in fibroblast growth factor receptor 3 (FGFR3) result in se

57 Stimulation of fibroblast growth factor receptor 3 (FGFR3) results in a

58 Aberrant fibroblast growth factor receptor 3 (FGFR3) signaling di

59 Research on the mutation in Fibroblast Growth Factor Receptor 3 (FGFR3) that causes

60 is associated with ectopic overexpression of fibroblast growth factor receptor 3 (FGFR3) that sometim

61 y of dimer formation of the G380R mutants of fibroblast growth factor receptor 3 (FGFR3) transmembran

62 for heterodimer formation between wild-type fibroblast growth factor receptor 3 (FGFR3) transmembran

63 hogenic mutations (V664E in Neu and A391E in fibroblast growth factor receptor 3 (FGFR3)) on receptor

64 Activating mutations within fibroblast growth factor receptor 3 (FGFR3), a receptor

65 ons that exaggerate the signal output of the fibroblast growth factor receptor 3 (FGFR3), a receptor

66 Activating mutations within fibroblast growth factor receptor 3 (FGFR3), a receptor

67 stitution in the transmembrane domain of the fibroblast growth factor receptor 3 (FGFR3), although th

68 ion mutations in a receptor tyrosine kinase, fibroblast growth factor receptor 3 (FGFR3), cause dwarf

69 estigated whether the TM domains of one RTK, fibroblast growth factor receptor 3 (FGFR3), dimerize in

70 nic mutation is the Ala391-->Glu mutation in fibroblast growth factor receptor 3 (FGFR3), linked to C

71 erozygous Pro250Arg substitution mutation in fibroblast growth factor receptor 3 (FGFR3), which incre

72 is caused by a gain-of function mutation in fibroblast growth factor receptor 3 (FGFR3).

73 tions on dimerization of TM domains of human fibroblast growth factor receptor 3 (FGFR3).

74 inomas contain activating point mutations of fibroblast growth factor receptor 3 (FGFR3).

75 r, previous results suggested a key role for fibroblast growth factor receptor 3 (FGFR3).

76 One candidate within this region is fibroblast growth factor receptor 3 (FGFR3).

77 titution of an amino acid with a cysteine in fibroblast growth factor receptor 3 (FGFR3).

78 rved activation loop of the kinase domain of fibroblast growth factor receptor 3 (FGFR3).

79 lasia or achondroplasia, in the TM domain of fibroblast growth factor receptors 3 (FGFR3).

80 The fibroblast growth factor-receptor 3 (FGFR3) Lys650 codon

81 sia caused by a gain-of-function mutation in fibroblast-growth-factor-receptor 3 (FGFR3).

82 g 11q13 (cyclin D1), 6p21 (cyclin D3), 4p16 (fibroblast growth factor receptor 3 [FGFR3] and multiple

83 expression of 2 potential oncogenes, FGFR3 (fibroblast growth factor receptor 3) from der(14) and mu

84 ge and the frequencies of sperm with DFI and fibroblast growth factor receptor 3 gene (FGFR3) mutatio

85 ustered in a 70-kb region centromeric to the fibroblast growth factor receptor 3 gene (FGFR3), the ap

86 result of distinct missense mutations in the fibroblast growth factor receptor 3 gene (FGFR3).

87 results from a single point mutation in the fibroblast growth factor receptor 3 gene on chromosome 4

88 Mutations in the gene for human fibroblast growth factor receptor 3 (hFGFR3) cause a var

89 rmation induced by the constitutively active fibroblast growth factor receptor 3 (K/E-FR3) (Oncogene,

90 rm of human achondrodysplasia, linked to the fibroblast-growth-factor receptor 3 locus, not linked to

91 ude HER2, epidermal growth factor receptors, fibroblast growth factor receptor 3, mTOR and others.

92 ctivity, including: CHIR-258, which inhibits fibroblast growth factor receptor 3; NVP-ADW742, which i

93 ) contains many scattered cells that express fibroblast growth factor receptor 3 transcripts (Fgfr3).

94 ransmembrane (TM) and kinase domains (KD) of fibroblast growth factor receptor 3, were introduced int