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1 ranulocyte colony-stimulating factor (G-CSF; filgrastim).
2  with granulocyte-colony-stimulating factor (Filgrastim).
3 tively (22% for paclitaxel 175 mg/m2 without filgrastim).
4 rvested with cyclophosphamide (2 g/m(2)) and filgrastim.
5 le or greater than those achieved with daily filgrastim.
6 yclophosphamide and 10 microg per kg per day filgrastim.
7  57 (40%) erythropoietin, and 17 of 57 (30%) filgrastim.
8 after mobilisation with cyclophosphamide and filgrastim.
9 relative to daily subcutaneous injections of filgrastim.
10 benefit to justify paclitaxel 250 mg/m2 plus filgrastim.
11 ilar to that provided by daily injections of filgrastim.
12 ncurrent AC x 4 --> T x 4 every 2 weeks with filgrastim.
13 utropenia and from 36 patients not receiving filgrastim.
14 4-hour infusions and supported with PBSC and filgrastim.
15                            Mobilization with filgrastim 10 microg/kg subcutaneous daily for 5 days wa
16 og/kg/d) plus Filgrastim (10 microg/kg/d) or Filgrastim (10 microg/kg/d) alone to mobilize peripheral
17 metHuSCF (5, 10, 15, or 20 microg/kg/d) plus Filgrastim (10 microg/kg/d) or Filgrastim (10 microg/kg/
18 ranulocyte colony-stimulating factor (G-CSF; Filgrastim) 10 microg/kg per day, for 7 days.
19 e colony-stimulating factor (r-met Hu G-CSF; filgrastim; 10 microgram/kg/day for 7 days) was used to
20 jection of pegfilgrastim (sustained-duration filgrastim) 100 micro g/kg per chemotherapy cycle (n = 3
21  in the patients who received r-metHuSCF and Filgrastim (12.5 v 23 days).
22 ere randomized to receive placebo (n=243) or filgrastim 300 microg/day (n=237), in addition to standa
23  Standard antibiotic therapy with or without filgrastim (300 microg/day) or placebo administered as a
24  = 33) with daily subcutaneous injections of filgrastim 5 micro g/kg (n = 33) in patients receiving s
25 e 20 mg/m(2) iv days1 through 5, followed by filgrastim 5 microg/kg subcutaneous starting approximate
26 5 mg/m2 and cyclophosphamide 750 mg/m2, with filgrastim 5 microG/kg/d subcutaneously beginning 24 hou
27                   All patients also received filgrastim 5 micrograms/kg administered subcutaneously b
28                        All patients received filgrastim (5 mcg/kg) daily until the absolute neutrophi
29 nd etoposide (500 mg/m2) for 14 cycles, with filgrastim (5 mg/kg per day; maximum, 300 mg) between cy
30 lung cancer were randomized to receive daily filgrastim (5 microg/kg/d) or a single injection of SD/0
31                                              Filgrastim (5 micrograms/kg/d) was administered subcutan
32    The duration of administration of SCF and filgrastim (7, 10, or 13 days) did not significantly aff
33 s of placebo (n = 21) or one of two doses of filgrastim (75 microg [n = 20] or 300 microg [n = 20]) f
34  mg/m2 and cyclophosphamide 1,250 mg/m2 with filgrastim administered every 21 days are the doses reco
35 itive stem cells to injured myocardium after filgrastim administration (control vs SDF-1-expressing c
36                         Contemporaneous with filgrastim administration for stem cell mobilization, th
37 filgrastim injection with daily subcutaneous filgrastim administration in pediatric patients receivin
38                                              Filgrastim administration was accompanied by similar sym
39  can be concluded that the administration of filgrastim after allogeneic blood stem cell transplantat
40 o receive one dose of pegfilgrastim or daily filgrastim after chemotherapy.
41 o determine whether further stimulation with filgrastim after transplantation would affect hematopoie
42 g filgrastim followed by cladribine and then filgrastim again to determine if filgrastim would lead t
43                              The addition of filgrastim allowed escalation of the topotecan dose to t
44                     Patients received either filgrastim alone (10 microg/kg/d for 7 days) or the comb
45 han 10 microg/kg/d, than for those receiving filgrastim alone (7.7 v 3.2 x 10(6)/kg, P < .05).
46 kaphereses) compared with patients receiving Filgrastim alone (median, 6 or more leukapherses; ie, <5
47  = 100) compared with 47% of those receiving Filgrastim alone (n = 103) reached the CD34(+) cell targ
48 tHuSCF and Filgrastim (N = 18) compared with Filgrastim alone (N = 5).
49 no major differences in outcomes between the filgrastim alone and the sequential regimens.
50 ion with Filgrastim at 10 micrograms/kg/d or Filgrastim alone at 10 micrograms/kg/d, from 203 patient
51                  Stem-cell mobilisation with filgrastim alone did not lead to engraftment of bone-mar
52 obilization of PBSC was achieved with either filgrastim alone or in combination with cyclophosphamide
53                        It was concluded that filgrastim alone or sequential sargramostim and filgrast
54              Treatment groups mobilized with filgrastim alone or with the cytokine combination had si
55 6)/kg) 7-day combination groups than for the filgrastim alone patients (median, 3.2 x 10(6)/kg).
56 enitor cell (PBPC)-mobilization regimen than Filgrastim alone.
57                                              Filgrastim, an analog for granulocyte colony-stimulating
58 7 days) or the combination of 10 microg/kg/d filgrastim and 5 to 30 microg/kg/d SCF for either 7, 10,
59 men with breast cancer chemotherapy received filgrastim and 6.8% received epoetin.
60 d as a 1-hour infusion at 60 mg/m(2) without filgrastim and at 60, 70, and 80 mg/m(2) with filgrastim
61                Thirty-five patients received filgrastim and cladribine and were compared with 105 his
62 etect any clinical advantage from the use of filgrastim and cladribine in the treatment of HCL.
63 ve times and 65 times more likely to receive filgrastim and epoetin, respectively, after controlling
64  recommendations include the addition of tbo-filgrastim and filgrastim-sndz, moderation of the recomm
65 nd topotecan can be safely administered with filgrastim and PBSC support.
66 er for patients receiving the combination of filgrastim and SCF, at doses greater than 10 microg/kg/d
67 ease in absolute neutrophil count, safety of filgrastim, and frequency of nosocomial infections (pneu
68 travenous infusion (CIVI) for 4 days without filgrastim, and paclitaxel 17.5 mg/m(2)/d CIVI for 4 day
69 e model protein lysozyme, the biotherapeutic filgrastim, and the Fc part of immunoglobulin G1.
70                        The administration of filgrastim appears to be a safe and effective supportive
71              Hematopoietic cytokines such as filgrastim are used extensively to stimulate granulocyte
72 BSCT were randomly assigned to receive daily filgrastim at 10 microg/kg or placebo starting on the da
73 F) at 20 micrograms/kg/d in combination with Filgrastim at 10 micrograms/kg/d or Filgrastim alone at
74 y cycle is comparable to daily injections of filgrastim at 5 microg/kg for pediatric sarcoma patients
75 PBSC donors were treated with 5 to 7 days of filgrastim at a dose of 16 microg/kg/d and underwent 1 t
76 esna was administered similarly (both arms); filgrastim began on day 4 (arm 2).
77                                              Filgrastim caused a dose-dependent increase in absolute
78 erapy, median ANC nadirs were similar in the filgrastim cohort and the cohort receiving SD/01 30 micr
79 both groups, CD34(+) cells were mobilized by filgrastim, collected via apheresis, and labeled with te
80 (range, 9-20 days) for patients who received filgrastim compared with 15 days (range, 10-22 days) for
81 (range, 8-35 days) for patients who received filgrastim compared with 15.5 days (range, 8-42 days) fo
82                                 Doubling the filgrastim dose from 5 to 10 microg/kg did not reduce th
83  and 18% on the 5-microg/kg and 10-microg/kg filgrastim dose, respectively (22% for paclitaxel 175 mg
84 stim dose of 100 microg/kg (n = 38) or daily filgrastim doses of 5 microg/kg (n = 6) after chemothera
85              We performed a study of priming filgrastim followed by cladribine and then filgrastim ag
86 y topotecan 0.75 mg/m2 daily for 5 days with filgrastim for amelioration of neutropenia.
87 geable levels of toxicity when combined with filgrastim for PBPC mobilization.
88 actor (SCF) administered in combination with filgrastim for the mobilization of peripheral blood prog
89 Food and Drug Administration approved G-CSF (filgrastim) for the treatment of congenital and acquired
90 ients were also randomly assigned to receive filgrastim (G-CSF) from day 0 until neutrophil count was
91  cyclophosphamide (CPA)/paclitaxel (Txl) and filgrastim (granulocyte colony-stimulating factor [G-CSF
92  peripheral-blood progenitor-cell (PBPC) and filgrastim (granulocyte colony-stimulating factor [G-CSF
93           This study evaluated the effect of filgrastim (granulocyte colony-stimulating factor [G-CSF
94 dy was performed to determine the effects of filgrastim (granulocyte colony-stimulating factor; G-CSF
95 re randomized to have HPC mobilization using filgrastim [granulocyte-colony-stimulating factor (G-CSF
96                                          The filgrastim group also had a trend for earlier discharge
97 grade 4 neutropenia in the pegfilgrastim and filgrastim groups was 69% and 68%, respectively.
98                          The group receiving filgrastim had a shorter time to neutrophil levels great
99 received sargramostim, patients who received filgrastim had faster recovery of an absolute neutrophil
100 Filgrastim or r-metHuSCF in combination with Filgrastim); however, when prior chemotherapy was taken
101 A x 4 --> T x 4 --> C x 4 every 2 weeks with filgrastim, (III) concurrent AC x 4 --> T x 4 every 3 we
102 , prednisone, and rituximab (DA-EPOCH-R) and filgrastim in untreated MGZL.
103 ranulocyte colony-stimulating factor (G-CSF; filgrastim) in an attempt to maximize delivered dose-int
104                                              Filgrastim increased the white blood cell count to a med
105                                              Filgrastim increased WBC counts (baseline median, 13.3x1
106 reatment was supported by daily subcutaneous filgrastim injections and reinfusion of 750 mL of autolo
107                      In conclusion, SCF plus Filgrastim is a more effective peripheral blood progenit
108                                              Filgrastim largely obviates neutropenic fever and allows
109           Fludarabine, cyclophosphamide, and filgrastim make up a highly active and well-tolerated re
110 tatistical significance, which suggests that filgrastim may reduce the decline of HIV-1 RNA loads.
111 et yield for the patients receiving SCF plus Filgrastim (median, 4 leukaphereses) compared with patie
112                     The study concluded that filgrastim mobilization, large volume apheresis, process
113 g donor adverse events (AEs) associated with filgrastim mobilized peripheral blood stem cell (PBSC) c
114 y), sirolimus, and infusion of unmanipulated filgrastim mobilized peripheral blood stem cells (5.5-31
115 igned to receive either allogeneic marrow or filgrastim-mobilized blood stem cell transplantation.
116    Marrow (BMT) was used for 44 patients and filgrastim-mobilized blood stem cells (SCT) for 41 patie
117 de that the transplantation of unmanipulated filgrastim-mobilized blood stem cells may result in a re
118  In a prospective randomized clinical trial, filgrastim-mobilized PBPCT resulted in faster recovery o
119 om a randomized clinical trial that compared filgrastim-mobilized PBPCT versus ABMT following carmust
120 om a randomized clinical trial that compared filgrastim-mobilized PBPCT versus ABMT.
121 y for 2 days) followed by transplantation of filgrastim-mobilized peripheral blood cells from HLA-ide
122 ly assigned to receive either bone marrow or filgrastim-mobilized peripheral-blood cells from HLA-ide
123 rials have shown that the transplantation of filgrastim-mobilized peripheral-blood stem cells from HL
124                                              Filgrastim-mobilized stem cells from HLA-identical relat
125 s, 63% of the patients treated with SCF plus Filgrastim (n = 100) compared with 47% of those receivin
126 (4)/kg) in patients receiving r-metHuSCF and Filgrastim (N = 18) compared with Filgrastim alone (N =
127 ifty-six patients were randomized to receive filgrastim (n = 51), sargramostim (n = 52), or sargramos
128  52), or sargramostim for 5 days followed by filgrastim (n = 53) after MC with either cyclophosphamid
129 sargramostim, or sequential sargramostim and filgrastim on CD34(+) cell yields and morbidity after my
130 ilgrastim and at 60, 70, and 80 mg/m(2) with filgrastim on day 1, and topotecan was administered at 0
131 g/m2 every 2 weeks x four cycles), requiring filgrastim on days 3 through 10 of each cycle has been s
132 y treatment cohort and mobilization regimen (Filgrastim or r-metHuSCF in combination with Filgrastim)
133 eral-blood stem cells (PBSCs) mobilized with filgrastim or the sequential regimen received higher num
134                                              Filgrastim, or granulocyte colony-stimulating factor, re
135 sical status starting with administration of filgrastim (PBSC donors) or after the marrow collection
136 so randomly assigned to 5 or 10 microg/kg of filgrastim per day subcutaneously.
137 limiting adverse effect, and the addition of filgrastim permitted the maintenance of dose-intensity i
138                                        After filgrastim priming, the median ANC increased from 0.9 x
139                          The hypothesis that filgrastim (r-met-huG-CSF) activates replication of mino
140 is study assessed the safety and efficacy of filgrastim (r-metHuG-CSF [recombinant human methionine g
141 pheral-blood cells mobilized with the use of filgrastim (recombinant granulocyte colony-stimulating f
142         Our results suggest that the CDE and filgrastim regimen is tolerable and effective for patien
143                                              Filgrastim regularly increases the ANC in patients with
144 cosylated recombinant forms, lenograstim and filgrastim, respectively, are used clinically to manage
145  of this study was to compare the effects of filgrastim, sargramostim, or sequential sargramostim and
146 ranulocyte colony-stimulating factor (G-CSF; filgrastim) shortens the time to neutrophil recovery aft
147 s include the addition of tbo-filgrastim and filgrastim-sndz, moderation of the recommendation regard
148                   Early studies suggest that filgrastim-stimulated bone marrow may confer some of the
149 ogenitors in the blood stem cell grafts from filgrastim-stimulated donors.
150 e randomized to receive 10 microg/kg per day filgrastim subcutaneously from day 1 through neutrophil
151                                              Filgrastim, sulfamethoxazole/trimethoprim, and acyclovir
152                                              Filgrastim, sulfamethoxazole/trimethoprim, and acyclovir
153 ted of fludarabine and cyclophosphamide with filgrastim support in patients with previously untreated
154  to respond or progressed could then receive filgrastim support or paclitaxel administered over 96 ho
155       Induction CIP was well tolerated (with filgrastim support) and active (partial response rate, 4
156  and mitoxantrone/diaziquone with or without filgrastim support.
157 d to achieve an AUC of 7 mg/mL x minute with filgrastim support.
158 table hematopoietic toxicity with the use of filgrastim support.
159 lerated by a large fraction of patients with filgrastim support.
160 nrolled at a starting dose of 8 mg/m2/d with filgrastim support.
161 apy was dose-intensified CHOP (CHOP-DI) with filgrastim support.
162 of 8 mg/m2/d was neutropenia with or without filgrastim support.
163 table hematopoietic toxicity with the use of filgrastim support.
164 clitaxel 17.5 mg/m(2)/d CIVI for 4 days with filgrastim support.
165 o achieve an AUC of 7 mg/mL x minute without filgrastim support; (2) paclitaxel 135 mg/m2 with a carb
166 d to achieve an AUC of 9 mg/mL x minute with filgrastim support; and (3) paclitaxel 225 mg/m2 with a
167 135 mg/m2 over 3 hours every 3 weeks without filgrastim support; the dose was increased as tolerated
168 ation with 600 mg/m2 of cyclophosphamide and filgrastim, the MTD of mitoxantrone is 28 mg/m2, a dose
169                        Six patients required filgrastim therapy for neutropenia.
170 sion, patients were randomly assigned G-CSF (filgrastim) therapy (n = 20) or placebo (n = 20) for 7 d
171                    He started treatment with filgrastim to facilitate collection of circulating hemat
172 ne and etoposide combined with rituximab and filgrastim to mobilize autologous peripheral-blood stem
173 ed from 36 HIV-1-infected patients receiving filgrastim to prevent neutropenia and from 36 patients n
174                              The addition of filgrastim to the antibiotic and supportive care treatme
175 ranulocyte colony-stimulating factor (G-CSF, filgrastim) to determine the effect of drug sequence on
176 greater than 1.0 x 10(9)/L was 9 days in the filgrastim-treated group versus 22 days among historic c
177 fter cladribine, the median nadir ANC in the filgrastim-treated group was 0.53 x 10(9)/L compared wit
178                                              Filgrastim-treated patients received a median of 11 inje
179 rees of env sequences from 3 subjects during filgrastim treatment contained unique intrasubject subcl
180  plasma quasi species present 5 years before filgrastim treatment than were the majority of the pretr
181 ence that increased HIV-1 replication during filgrastim treatment was associated with activation of H
182 th activation of HIV-1 variants that, before filgrastim treatment, were minor components of the plasm
183  unique subclusters were not detected before filgrastim treatment, yet they composed 40%-70% of the p
184 n whom plasma HIV-1 RNA had increased during filgrastim treatment.
185 n of PBPCs, patients received 10 microg/kg/d filgrastim until absolute neutrophil count recovery.
186 0) HIV-1 RNA level for individuals receiving filgrastim versus those not receiving the drug of 5.11 v
187                                              Filgrastim was administered at 5 micrograms/kg/d subcuta
188           In this patient population, use of filgrastim was safe and the agent appeared to reduce the
189 ll be required to validate this observation, filgrastim was safe and well tolerated when administered
190              A dose of 5 microg/kg of G-CSF (Filgrastim) was given subcutaneously each day for 5 days
191                    Results Pegfilgrastim and filgrastim were similar for all efficacy and safety end
192 grastim alone or sequential sargramostim and filgrastim were superior to sargramostim alone for the m
193 hylactic corticosteroids, ciprofloxacin, and filgrastim were used.
194   Accordingly, the routine adjunctive use of filgrastim with cladribine in the treatment of HCL canno
195 ion of 20 microg/kg/d SCF and 10 microg/kg/d filgrastim with daily apheresis beginning on day 5 was s
196 se of granulocyte colony-stimulating factor (filgrastim) with or without transplantation of syngeneic
197  when given on an every 2-week schedule with filgrastim, with encouraging antitumor activity observed
198 , prednisone, and rituximab (DA-EPOCH-R) and filgrastim without radiotherapy in 51 patients with untr
199 ne and then filgrastim again to determine if filgrastim would lead to a reduction of neutropenia and
200                        Patients who received filgrastim yielded more CD34(+) cells (median, 7.1 v 2.0

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