ライフサイエンスコーパス: filtration barrier

1 to their function in maintaining the kidney filtration barrier.

2 e tetraspanin CD151 to maintain a functional filtration barrier.

3 aintaining the characteristics of the kidney filtration barrier.

4 rane (GBM) in order to maintain a functional filtration barrier.

5 podocytes, a key component of the glomerular filtration barrier.

6 ion and maintenance of the kidney glomerular filtration barrier.

7 ctural framework for a functional glomerular filtration barrier.

8 the structure and function of the glomerular filtration barrier.

9 A (VEGFA) maintains a functional glomerular filtration barrier.

10 ture of the slit diaphragm in the glomerular filtration barrier.

11 a role in the maintenance of the glomerular filtration barrier.

12 ch are critical components of the glomerular filtration barrier.

13 for the establishment of a normal glomerular filtration barrier.

14 quired for proper function of the glomerular filtration barrier.

15 emove immunoglobulins that accumulate at the filtration barrier.

16 i but is critical to maintain the glomerular filtration barrier.

17 ffects on cells that comprise the glomerular filtration barrier.

18 red for proper functioning of the glomerular filtration barrier.

19 itical role in the maintenance of the kidney filtration barrier.

20 maintaining the integrity of the glomerular filtration barrier.

21 s found to cover 58 to 65% of the glomerular filtration barrier.

22 ar filtration and cleaning of the glomerular filtration barrier.

23 in in the development of a normal glomerular filtration barrier.

24 e as the central component of the glomerular filtration barrier.

25 cytes, cells that are a critical part of the filtration barrier.

26 novel role for kidney apoE in preserving the filtration barrier.

27 been linked to the maintenance of the kidney filtration barrier.

28 rom neighboring cells to form the glomerular filtration barrier.

29 maintaining the integrity of the glomerular filtration barrier.

30 ed macromolecules and the maintenance of the filtration barrier.

31 hat act as a key component of the glomerular filtration barrier.

32 elial cells that reside along the glomerular filtration barrier.

33 h induced severe edema and disruption of the filtration barrier.

34 evelopment and maintenance of the glomerular filtration barrier.

35 l for the maintenance of a normal glomerular filtration barrier.

36 effacement and impairment of the glomerular filtration barrier.

37 ural and functional roles in maintaining the filtration barrier.

38 Excess sema3a disrupts the glomerular filtration barrier.

39 he structure and integrity of the glomerular filtration barrier.

40 is critical to ensure integrity of the blood filtration barrier.

41 complex, an important part of the glomerular filtration barrier.

42 synapse formation to formation of the kidney filtration barrier.

43 helial cells that line the kidney glomerular filtration barrier.

44 ural and functional regulation of the kidney filtration barrier.

45 anosensation and the integrity of the kidney filtration barrier.

46 uptake for the maintenance of the glomerular filtration barrier.

47 sential component of the kidney's glomerular filtration barrier.

48 epresent a key constituent of the glomerular filtration barrier.

49 grity of which is crucial for the glomerular filtration barrier.

50 involving the three layers of the glomerular filtration barrier.

51 sustaining the mechanical resistance of the filtration barrier.

52 subepithelial location along the glomerular filtration barrier 14 days after antibody injection, and

53 ells form altogether comprise the glomerular filtration barrier, a dynamic and highly selective filte

54 ephropathy (DN) is highlighted by glomerular filtration barrier abnormalities.

55 nvolved in the maintenance of the glomerular filtration barrier and are key targets of injury in many

56 are an essential component of the glomerular filtration barrier and cover the outer aspect of glomeru

57 , these mutants failed to establish a normal filtration barrier and exhibited severe proteinuria due

58 y role both in maintenance of the glomerular filtration barrier and in glomerular structural integrit

59 drome results from a breakdown of the kidney filtration barrier and is associated with proteinuria, h

60 B-domain protein podocin maintains the renal filtration barrier and its mutation is an important caus

61 e slit diaphragm cell junction at the kidney filtration barrier and part of a multiprotein-lipid supe

62 essential components of the renal glomerular filtration barrier and podocyte dysfunction leads to pro

63 hening this interaction may protect kidney's filtration barrier and preserve kidney function.

64 maintaining the integrity of the glomerular filtration barrier and preventing urinary protein leakag

65 maintaining the integrity of the glomerular filtration barrier and provide insight into the pathogen

66 al podocyte proteins cause disruption of the filtration barrier and rearrangement of the highly dynam

67 cal during the development of the glomerular filtration barrier and required for the proper function

68 acids (NEFAs) across the damaged glomerular filtration barrier and subsequent reabsorption by the do

69 ion of proteins that traverse the glomerular filtration barrier and that is also involved in the exte

70 ssential for the integrity of the glomerular filtration barrier and that this protein is a key determ

71 g technology for the study of the glomerular filtration barrier and the controversy it recently gener

72 the direct injurious effects of TWEAK on the filtration barrier and/or modulation of cytokine product

73 odocyte as a key component of the glomerular filtration barrier, and hence an important common pathwa

74 ytes are a major component of the glomerular filtration barrier, and their ability to sense insulin i

75 cytes are key components of the kidney blood filtration barrier, and their ability to withstand hemod

76 at are critical components of the glomerular filtration barrier, and their dysfunction leads to prote

77 cesses are an essential part of the kidney's filtration barrier, and their structure is regulated pri

78 Diseases of the kidney filtration barrier are a leading cause of ESRD.

79 t are critical in the formation of the renal filtration barrier are found to be regulated in associat

80 onsequently, the integrity of the glomerular filtration barrier are incompletely understood.

81 o, but its in vivo effects on the glomerular filtration barrier are not well described.

82 Podocytes, as an important component of the filtration barrier, are susceptible to lipid disorders.

83 tic syndrome (NS) occurs when the glomerular filtration barrier becomes excessively permeable leading

84 es is critical to form the normal glomerular filtration barrier, but the molecular programs driving t

85 evelopment and maintenance of the glomerular filtration barrier, but the pathogenic role of excessive

86 ne has the potential to alter the glomerular filtration barrier by compromising the integrity of podo

87 veloped a functional assay of the glomerular filtration barrier by creating transgenic zebrafish expr

88 critical role in maintaining the glomerular filtration barrier by modulating the bioavailability of

89 s microalbuminuria resulting from glomerular filtration barrier damage.

90 ate for the loss of Lambeta2, leading to the filtration barrier defects and nephrotic syndrome.

91 of Fat1 in mice induces abnormal glomerular filtration barrier development, leading to podocyte foot

92 for normal kidney patterning and glomerular filtration barrier development.

93 sal end point of podocyte injury, glomerular filtration barrier disruption, and SRNS.

94 aining podocytes in vivo could contribute to filtration barrier dysfunction.

95 layer (ESL) has been postulated to act as a filtration barrier for large molecules, such as albumin.

96 tein expressed in kidney that is part of the filtration barrier formed by podocytes.

97 docyte differentiation state is critical for filtration barrier function and is regulated by WT1, a z

98 Podocytes are important for glomerular filtration barrier function and maintenance of size sele

99 in human diabetic nephropathy and may alter filtration barrier function and systolic BP through the

100 The glomerulus exercises its filtration barrier function by establishing a complex fi

101 d apoptosis, hypermotility and impairment of filtration barrier function equally in primary podocytes

102 cyte differentiation and impaired glomerular filtration barrier function, with development of pericar

103 sion of differentiation markers and improved filtration barrier function.

104 ith the glomerular capillary bed to maintain filtration barrier function.

105 for maintenance of glomerular endothelia and filtration barrier functional integrity, respectively.

106 nd nitric oxide are essential for glomerular filtration barrier homeostasis and are dysregulated in d

107 the structure and function of the glomerular filtration barrier; however, they also exhibit increased

108 uggest that albumin loss through the damaged filtration barrier impairs podocyte regeneration by sequ

109 a direct protective effect on the glomerular filtration barrier in FSGS.

110 xamined the effect of morphine on glomerular filtration barrier in general and podocyte integrity in

111 the structure and function of the glomerular filtration barrier in the adult kidney.

112 Podocytes help form the glomerular blood filtration barrier in the kidney and their injury or los

113 As an integral member of the filtration barrier in the kidney glomerulus, the podocyt

114 ized cells of the kidney that form the blood filtration barrier in the kidney glomerulus.

115 erminally differentiated cells that act as a filtration barrier in the kidney.

116 process effacement on long stretches of the filtration barrier in the zebrafish knockdown model and

117 calyx in protein leakage over the glomerular filtration barrier, in an immunogold labeling study of i

118 ria accompanied by structural changes in the filtration barrier, including podocyte foot process effa

119 we found that the ion channel TRPC5 mediates filtration barrier injury.

120 morphogenesis and maintenance of glomerular filtration barrier integrity is poorly understood.

121 rafish morphants caused a loss of glomerular filtration barrier integrity, podocyte foot process effa

122 ng an important role of THSD7A in glomerular filtration barrier integrity.

123 define its role in maintenance of glomerular filtration barrier integrity.

124 sually caused by deterioration of glomerular filtration barrier integrity.

125 of renal disease owing to the disruption of filtration barrier integrity.

126 ases, loss of size selectivity by the kidney filtration barrier is associated with changes in the mor

127 The kidney filtration barrier is comprised of the endothelial linin

128 ate of internalization is increased when the filtration barrier is disrupted.

129 The glomerular filtration barrier is known as a 'size cutoff' slit, whi

130 ship with other components of the glomerular filtration barrier is of great interest in this field.

131 the central question of whether the primary filtration barrier is the basement membrane or the epith

132 gm (SD), the major constituent of glomerular filtration barrier, is still unclear.

133 terations to the structure of the glomerular filtration barrier lead to effacement of podocyte foot p

134 th glomerular diseases have an injured renal filtration barrier, leading to proteinuria and reduced r

135 isruption of any component of the glomerular filtration barrier leads to glomerular dysfunction, freq

136 Ctnnb1 expression is critical for glomerular filtration barrier maintenance.

137 Glycosaminoglycans (GAGs) contribute to the filtration barrier of aqueous outflow through the trabec

138 Podocytes are critical in maintaining the filtration barrier of the glomerulus and are dependent o

139 tes are critical components of the selective filtration barrier of the glomerulus and are susceptible

140 Ultrastructurally, the glomerular filtration barrier of the Gsalpha-deficient animals feat

141 ocyte is a critical cell for maintaining the filtration barrier of the kidney and preventing albuminu

142 adherens junction that comprises the protein filtration barrier of the kidney, and interacts with a n

143 he integrity of podocytes and the glomerular filtration barrier of the kidney.

144 entiated cells and critical elements for the filtration barrier of the kidney.

145 a central role in maintaining the selective filtration barrier of the renal glomerulus.

146 changes in ultrastructure of the glomerular filtration barrier on the vascular side of the glomerula

147 ocal segmental glomerulosclerosis, increased filtration barrier permeability is restricted only to ar

148 The glomerular filtration barrier prevents large serum proteins from be

149 The mechanisms by which the glomerular filtration barrier prevents the loss of large macromolec

150 Damage to the filtration barrier results in albumin loss in the urine,

151 terogeneous disorder of the renal glomerular filtration barrier, results in impairment of glomerular

152 A functional assay of glomerular filtration barrier revealed that absence of normal nephr

153 oteins, suggesting failure of the glomerular filtration barrier sieving properties, or different coll

154 y prevented albuminuria, restored glomerular filtration barrier structure, and markedly reduced glome

155 ialized epithelial cells of the kidney blood filtration barrier that contribute to permselectivity vi

156 ant role in maintaining the structure of the filtration barrier that prevents proteins from freely en

157 as an essential component of the glomerular filtration barrier that promotes podocyte survival by in

158 The glomerular capillaries function as the filtration barrier that retains albumin and other plasma

159 Here, we show that a component of the renal filtration barrier--the glomerular basement membrane (GB

160 gial matrix is associated with disruption of filtration barrier, these data suggest a novel role for

161 s involved in the response of the glomerular filtration barrier to injury, we studied freshly isolate

162 rminant required for the kidney's glomerular filtration barrier to plasma protein.

163 of dynamin in the maintenance of the kidney filtration barrier via an action on the actin cytoskelet

164 which podocytes sense the disruption of the filtration barrier via FFAs bound to albumin and respond

165 lay an integral role in the renal glomerular filtration barrier via their foot processes.

166 his severe charge disruption, the glomerular filtration barrier was not compromised, even when challe

167 se lesions and dysfunction of the glomerular filtration barrier were associated with FSGS in endothel

168 ucidated that murine cells of the glomerular filtration barrier were unresponsive to Stx2 because the

169 for particular components of the glomerular filtration barrier) were used to determine the exact loc

170 ial-podocyte crosstalk across the glomerular filtration barrier, whereby the actions of one type of c