ライフサイエンスコーパス: fimbriae

1 t epithelium via thin fibers called pili (or fimbriae).

2 d S Typhi strains with a deletion in the stg fimbriae.

3 r their ability to produce surface-assembled fimbriae.

4 were used to investigate the role of type 1 fimbriae.

5 nce-associated surface fibers termed pili or fimbriae.

6 le bacteria expressing S. Typhimurium type 1 fimbriae.

7 between cellular receptors and Gram-positive fimbriae.

8 antly reduced surface assembly of the type 1 fimbriae.

9 serve as fimbrial receptors, involves type 1 fimbriae.

10 hat assembles adhesive fibres termed pili or fimbriae.

11 at enables the rapid deployment of bacterial fimbriae.

12 mponents of a machinery allowing assembly of fimbriae.

13 5% of all UTI-causing E. coli express type 1 fimbriae.

14 olymerization mechanism of the P. gingivalis fimbriae.

15 uman extracellular matrices using the type 3 fimbriae.

16 (minor) fimbriae and the 41-kDa fimA (major) fimbriae.

17 was achieved with the antibody against CFA/I fimbriae.

18 FimH adhesins capping the distal end of its fimbriae.

19 , from colonization factor antigen I (CFA/I) fimbriae.

20 ve and virulence properties to P. gingivalis fimbriae.

21 e production of at least 10 of its predicted fimbriae.

22 ls following stimulation with major or minor fimbriae.

23 nisation in atypical/FGL-chaperone assembled fimbriae.

24 opulation-level control of the expression of fimbriae.

25 ooth model, is mediated by long peritrichous fimbriae.

26 only one of these adhesins, known as type 1 fimbriae.

27 uous 54-kb flagellar regulon and 17 types of fimbriae.

28 utational model to simulate the evolution of fimbriae.

29 lithiasis, and mannose-resistantProteus-like fimbriae.

30 ent on the expression of the major and minor fimbriae.

31 here to the in vitro tooth model and to form fimbriae.

32 erotoxigenic Escherichia coli (ETEC) Class 5 fimbriae.

33 mB proteins, but it does not assemble type 2 fimbriae.

34 the surface of bacterial pathogens, such as fimbriae.

35 that is essential for assembly of the type 2 fimbriae.

36 e 1 activation irrespective of P. gingivalis fimbriae.

37 ibuted to this biomechanical feature of ETEC fimbriae.

38 lence factors in particular: urease and MR/P fimbriae.

39 and mode of binding by the poly-adhesive F4 fimbriae.

40 iring adherence factors such as flagella and fimbriae.

41 n the GI tract, promoted expression of these fimbriae.

42 ess stable, non-oxidized DraE forms into the fimbriae.

43 s required for expression of plasmid-encoded fimbriae.

44 e by specifically increasing production of P fimbriae.

45 major structural subunit of plasmid-encoded fimbriae.

46 sly assessed biomechanical properties of the fimbriae.

47 owever, SL1344DeltafimI was able to assemble fimbriae.

48 Long polar fimbriae 1 (Lpf1) of Escherichia coli O157:H7 is a tight

49 toxin (PT), filamentous hemagglutinin (FHA), fimbriae 2 + 3 (FIMs), diphtheria, tetanus, Hib, MCC and

50 Type 1 fimbriae, a major UPEC virulence factor, are essential f

51 factors, including the aggregative adherence fimbriae (AAF), dispersin, the dispersin translocator Aa

52 tissue is mediated by aggregative adherence fimbriae (AAF); however, the receptors involved in EAEC

53 ed the presence of the aggregative adherence fimbriae (AAFs) by a multiplex PCR, targeting the four k

54 Expression of aggregative adherence fimbriae (AAFs), the principal adhesins of EAEC, was req

55 herence is mediated by aggregative adherence fimbriae (AAFs), which are encoded on the pAA virulence

56 e significantly longer on average, with many fimbriae able to stretch to >20 microm in length.

57 Therefore, P. gingivalis fimbriae activate two distinct TLR2 pathways mediating p

58 of the reported protein agonists, PG1828 and fimbriae, activate TLR2 as strongly as the wild type.

59 ight compound that inhibits FimH, the type 1 fimbriae adhesin, significantly reduced bacterial coloni

60 h urine and along mucus layers, while type 1 fimbriae allow bacteria to adhere to specific receptors

61 Strikingly, native fimbriae allowed P. gingivalis to exploit the TLR2/compl

62 However, it is unclear whether CFA/I fimbriae alone are protective and whether other regulato

63 on of mfa, encoding the subunit of the short fimbriae, along with higher levels of Mfa protein.

64 Fimbriae (also known as pili) are appendages that extend

65 ances binding affinity and triggers multiple fimbriae anchoring.

66 genes, encoding the major protein subunit of fimbriae and an arginine-specific proteinase, respective

67 C colonization genes encoding type 1 and F1C fimbriae and capsule biosynthesis were transcriptionally

68 ayfiR suppressed the overproduction of curli fimbriae and cellulose and further verified that deletio

69 Curli fimbriae and cellulose production were increased in the

70 of csgD and bcsA, genes necessary for curli fimbriae and cellulose production, respectively, returne

71 This mutant produces abundant type 1 fimbriae and expresses the monomeric FimA and FimB prote

72 Type 1 fimbriae and flagella have been previously shown to cont

73 Both fimbriae and flagella have been proven important for vir

74 cesses of adhesion and motility, mediated by fimbriae and flagella, respectively, is essential for di

75 Type 1 fimbriae and flagella, two surface organelles critical f

76 The DraD/AfaD subunit caps fimbriae and has been implicated in the entry of Dr-fimb

77 nal colonization factors (CFs) such as CFA/I fimbriae and heat-labile enterotoxin (LT) are important

78 i CFT073 leads to elevated expression of PAP fimbriae and hemolysin by an unknown mechanism.

79 or the guaB gene in the regulation of type 1 fimbriae and in colonisation of the mouse bladder.

80 genes, which leads to the production of CupD fimbriae and increased attachment.

81 uinis, is the major constituent of bacterial fimbriae and is required for adhesion and biofilm format

82 ns of Escherichia coli on the tips of type 1 fimbriae and mediates adhesion via a catch bond to its l

83 equence of ArcA that repressed expression of fimbriae and of gingipains.

84 nstruct that constitutively expresses type 1 fimbriae and represses motility, we identified six mutan

85 shown to block CR3 binding of P. gingivalis fimbriae and reverse IL-12p70 inhibition; specifically,

86 thogenicity of ETEC expressing newer class 5 fimbriae and suggest suitability of the LT|CS17-ETEC cha

87 least two adhesins: the 67-kDa mfa-1 (minor) fimbriae and the 41-kDa fimA (major) fimbriae.

88 infections are associated with production of fimbriae and the formation of a biofilm.

89 Purified Std fimbriae and UEA both bound to a receptor localized in t

90 st, the fimA and srtC2 mutants lacked type 2 fimbriae and were non-adherent in each of these assays.

91 tigen fraction 1 (F1), the pH 6 antigen (Psa fimbriae), and the outer membrane protease Pla, on the b

92 chinery, capsule, lipopolysaccharide, type 1 fimbriae, and iron acquisition systems during UTI.

93 lysaccharide (LPS) and lipid A, lipoprotein, fimbriae, and phosphorylated dihydroceramides of P. ging

94 gly dependent upon minor constituents of its fimbriae, and support the concept that pathogens evolved

95 Type 1 fimbriae are a known virulence factor in a number of pat

96 Summary Fimbriae are adhesive organelles known to enable pathoge

97 for the first time, demonstrated that these fimbriae are associated with adherence and hemagglutinat

98 ETEC strains expressing F4 fimbriae are associated with neonatal and post-weaning d

99 S. Typhimurium type 1 fimbriae are characterized by mannose-sensitive hemagglu

100 esults show atypical/FGL-chaperone assembled fimbriae are composed of highly flexible linear multi-su

101 Dr fimbriae are comprised of two subunits.

102 Two types of adhesive fimbriae are expressed by Actinomyces; however, the arch

103 The three fimbriae are expressed by ETEC, colonize in similar gut

104 Fimbriae are filamentous structures whose shafts are pri

105 The structural components of the fimbriae are FimA (major subunit), FimI, FimH (adhesin),

106 Dr fimbriae are homopolymeric adhesive organelles of uropat

107 , we are able to show that type 1 and type 3 fimbriae are important colonization factors in the murin

108 st that in Salmonella spp., wild-type type 1 fimbriae are important for attachment to and/or persiste

109 Studies have shown that type 1 and type 3 fimbriae are involved in attachment and biofilm formatio

110 This study reveals that major fimbriae are involved in the initial invasion of osteobl

111 strains, but for the most potent UPEC type 1 fimbriae are involved.

112 Fimbriae are protein-based filamentous appendages that p

113 P fimbriae are strongly associated with upper urinary trac

114 chia coli (ETEC) strains expressing K88 (F4) fimbriae are the major cause of diarrhea in young pigs.

115 The best-studied examples of fimbriae are the type 1 and P fimbriae of uropathogenic

116 cterize the protective properties of the Psa fimbriae are warranted.

117 Escherichia coli (UPEC), flagella and type 1 fimbriae, are critical for colonization of the urinary t

118 ese extracellular structures, called pill or fimbriae, are employed in attachment and invasion, biofi

119 yromonas gingivalis, as well as its purified fimbriae, are known to activate TLR2 and induce proinfla

120 Using coli surface antigen 20 (CS20) fimbriae as a model ETEC colonization factor, we show us

121 Recent understanding about the role of fimbriae as virulence factors points to an evolutionary

122 tor responsible for the expression of type I fimbriae as well as flagellar genes, has also been impli

123 The presence of multiple types of fimbriae assembled by the chaperone/usher pathway can be

124 The biophysical properties of CS2 fimbriae assessed in this work classify them into a low-

125 Fimbriae-associated protein (Fap1) from Streptococcus pa

126 ed that the synthesis and presence of type 1 fimbriae at the bacterial surface is only partially resp

127 als without detectable chlamydial DNA in the fimbriae at weeks 5 and 12.

128 In Escherichia coli type 1 and Pap fimbriae, at least two adaptors are expressed in additio

129 olled by the major subunit (FaeG) of the K88 fimbriae, because the genes coding for the only other fi

130 along a mannosylated surface under flow, the fimbriae bend and buckle as they interact with the surfa

131 rbent assay (ELISA) in which plasmid-encoded fimbriae bound Le(x)-coated wells in a concentration-dep

132 Major and minor fimbriae bound to a human TLR2:Fc chimeric protein with

133 r ability to uncoil under exposure to force, fimbriae can reduce fluid shear stress on the adhesin-re

134 4), and bacteria expressing FimCDE-deficient fimbriae cannot exploit CXCR4 in vivo for promoting thei

135 to be MrkA, a major protein in the type III fimbriae complex, and showed that these serotype-indepen

136 that the fimB mutant, which produced type 2 fimbriae composed only of FimA, like the wild type co-ag

137 athogen partially depends upon expression of fimbriae comprising polymerized fimbrillin (FimA) associ

138 ed assay with E. coli expressing mutant F4ad fimbriae confirmed the elucidated co-complex structure.

139 in the mouse model, demonstrating that these fimbriae contribute to uropathogenesis.

140 th P. gingivalis ATCC 33277 or YPF1, a major fimbriae-deficient mutant of P. gingivalis.

141 ranscripts in response to P. gingivalis in a fimbriae-dependent manner.

142 ectional, where the overexpression of type 1 fimbriae dramatically affects motility and flagellum exp

143 d process, and, therefore, the role of these fimbriae during binding to epithelial cells has been dif

144 (S. typhimurium) to the production of type I fimbriae encoded by the fimAICDHF operon.

145 of fimbriae together with the CFA/I and CS20 fimbriae expressed by ETEC strains.

146 impact on the biophysical characteristics of fimbriae expressed by ETEC.

147 On the other hand, the fimbriae expressed by the mutants are significantly long

148 rt across the inner membrane, fewer FimH and fimbriae expressed on the bacterial surface, and decreas

149 elicit a host-based nutrient release if the fimbriae expression is low.

150 imB gene that controls phase-variable type 1 fimbriae expression via the invertible fimS promoter.

151 strains causes altered regulation of type 1 fimbriae expression.

152 Three naturally occurring variants of F4 fimbriae (F4ab, F4ac, and F4ad) exist that differ in the

153 Type 1 fimbriae facilitate adhesion to mucosal cells and promot

154 ) (17 [71%] vs 62 [47%]; P = .03) and prf (P-fimbriae family) (13 [54%] vs 40 [30%]; P = .02) were mo

155 Two types of fimbriae, FimA and Mfa1, of the periodontal pathogen Por

156 e adhesive, tip-associated subunit of type 1 fimbriae (FimH) are positively selected in uropathogenic

157 e gene content, the possession of the type 1 fimbriae FimH30 allele, and the production of the CTX-M-

158 The targeted bacterial antigens were CFA/I fimbriae, flagella, lipopolysaccharides (LPS), and capsu

159 , indicating the specialized function of Mad fimbriae for symbiosis.

160 eria, enterics use cellulose and aggregative fimbriae for their attachment to plant surfaces.

161 s-associated and temperature-regulated (Mat) fimbriae) for E. coli serotypes O157:H7 and O18:K1:H7.

162 Tip-localized adhesive proteins of bacterial fimbriae from diverse pathogens confer protection in ani

163 drate binding specificity of plasmid-encoded fimbriae from S. Typhimurium.

164 vestigated the biophysical properties of CS2 fimbriae from the CFA/II group.

165 structural similarities seen between class 5 fimbriae (from bacteria primarily causing gastrointestin

166 by which intestinal antibodies against ETEC fimbriae function to prevent disease.

167 However, E. coli type 1 and Pap fimbriae have been reported to be able to assemble fimbr

168 tisubunit protein polymers, known as pili or fimbriae, have a pivotal role in the colonization of spe

169 other systems, including flagella and type 1 fimbriae, have been implicated in Salmonella pathogenesi

170 e caused by strains that express K88 (F4)(+) fimbriae, heat-labile enterotoxin (LT), heat-stable ente

171 This functional effect of longer fimbriae highlights the importance of the nonadhesive fi

172 60A the impAB and the aggregative adherence fimbriae I (AAF/I)-encoding genes are on the same large

173 hat the AggR-regulated aggregative adherence fimbriae I enhance inflammation and enable the outbreak

174 ayers, implicating the aggregative adherence fimbriae II (AAF/II) as necessary for barrier dysfunctio

175 sly been attributed to aggregative adherence fimbriae II (AAF/II), which confer aggregative adherence

176 tion of the biomechanical properties of CS20 fimbriae impedes sustained adhesion of ETEC to the intes

177 P-induced IL-1beta secretion by means of its fimbriae in a purinergic P2X7 receptor-dependent manner.

178 t of PI3K and was activated by P. gingivalis fimbriae in a TLR2- and PI3K-dependent way, Akt was show

179 In agreement with the role of type 1 fimbriae in binding to PRPs, aggregation of A. oris with

180 One hypothesis of the role of fimbriae in commensals is that they evoke a small but to

181 recombinase to control expression of type I fimbriae in E. coli.

182 erythrocytes coursing over immobilized CFA/I fimbriae in flow chambers exhibited low accumulation lev

183 pe of infection, we investigated the role of fimbriae in implant-associated urinary tract infections

184 However, the role of fimbriae in P. gingivalis-osteoblast interactions remain

185 e encoding the major protein subunit of long fimbriae in P. gingivalis; as a result, S. cristatus int

186 Type I fimbriae in Salmonella enterica serovar Typhimurium are

187 The production of type 1 fimbriae in Salmonella enterica serovar Typhimurium is c

188 ae have been reported to be able to assemble fimbriae in the absence of these proteins.

189 the present study, the involvement of major fimbriae in the initial and long-term interactions betwe

190 ng bacterial mutants demonstrated a role for fimbriae in the modulation of TLR-mediated activation of

191 Expression of Std fimbriae in the rosE mutant resulted in increased attach

192 eover, the constitutive expression of type 1 fimbriae in UPEC cystitis isolate F11 and the laboratory

193 Expression of MR/P fimbriae increases in a cell-density dependent manner in

194 d -DeltafimF mutants were unable to assemble fimbriae, indicating that these genes are necessary for

195 cherichia coli colonization factor antigen I fimbriae, initiates binding of this enteropathogen to th

196 One class of these fimbriae is assembled using a periplasmic chaperone and

197 ause the fim operon encoding adhesive type 1 fimbriae is incomplete.

198 Highlighting the importance of MR/P fimbriae is the cotranscribed regulator, MrpJ, which glo

199 Lpf (stands for long polar fimbriae) is one of the few adhesive factors of enterohe

200 CfaA, CfaB, the major pilin subunit of CFA/I fimbriae, is able to spontaneously refold and polymerize

201 function as the major adhesin of the type 1 fimbriae, it also plays an important role in fimbrial as

202 Three antigenic variants of K88 fimbriae (K88ab, K88ac, and K88ad) have been identified

203 disruption mutant with reduced expression of fimbriae lacking all accessory proteins.

204 We now show that P. gingivalis fimbriae lacking FimCDE fail to interact with the CXC-ch

205 Constitutive expression of type 1 fimbriae leads to repression of motility and chemotaxis

206 Fimbriae, lipopolysaccharide (LPS), and extracellular po

207 usly we showed that EHEC produces long polar fimbriae (LPF) and that maximum expression is observed d

208 The expression of the long polar fimbriae (LPF) of enterohemorrhagic Escherichia coli (EH

209 xpress an adherence factor called long polar fimbriae (LPF) that aids in the binding of these bacteri

210 r enhanced by introduction of the long polar fimbriae (Lpf), which facilitate adherence of S Typhimur

211 curli and two operons that encode long polar fimbriae (Lpf).

212 The amounts of fimbriae, LPS, and EPS were also estimated from stained

213 Increased expression of type-1 fimbriae may enhance bacterial interference without conf

214 Type 1 fimbriae mediate adhesion of uropathogenic Escherichia c

215 he failure of this polysaccharide to support fimbriae-mediated adhesion of Actinomyces naeslundii was

216 ant strain, E. coli 83972::lgtCE, impaired P fimbriae-mediated adhesion to human erythrocytes and kid

217 In contrast, CFA/I fimbriae-mediated protection was abated in EBI3(-/-) mic

218 enic major (DPG-3)-, minor (MFI)-, or double fimbriae (MFB)-deficient mutant P. gingivalis strains.

219 actors, including expression of type I and P fimbriae, modulation of hemolysin expression, and expres

220 is dependent on DC-SIGN, whereas the double fimbriae mutant strain does not bind.

221 Using a P. gingivalis major and minor fimbriae mutant, we confirmed that TLR2 binding in whole

222 The type 1 fimbriae of Actinomyces naeslundii T14V mediate adhesion

223 lass 5 colonization factor antigen I (CFA/I) fimbriae of enterotoxigenic E. coli was proposed to proc

224 Class 5 fimbriae of enterotoxigenic Escherichia coli (ETEC) comp

225 pecific adhesin located on the tip of type 1 fimbriae of Escherichia coli that is capable of mediatin

226 Type 1 fimbriae of Escherichia coli, which are likewise subject

227 We have previously shown that the fimbriae of P. gingivalis interact with complement recep

228 The fimbriae of Porphyromonas gingivalis mediate critical ro

229 FimH is the adhesive subunit of type 1 fimbriae of the Escherichia coli that is composed of a m

230 Fimbriae of the human uropathogen Proteus mirabilis are

231 The major fimbriae of this periodontal pathogen mediate binding to

232 ed examples of fimbriae are the type 1 and P fimbriae of uropathogenic Escherichia coli, the major ca

233 MR/P fimbriae of uropathogenic Proteus mirabilis undergo inve

234 Here we showed that the highly conserved Psa fimbriae of Y. pestis (also called pH 6 antigen) are exp

235 pression of DC-SIGN on MoDCs and minor mfa-1 fimbriae on P. gingivalis and is evidenced by robust upr

236 and Mfa4, into fibers and the expression of fimbriae on the cell surface.

237 due to the constitutive expression of type 1 fimbriae on the surfaces of the bacteria and that multip

238 ria assemble hair-like fibers termed pili or fimbriae on their cell surface.

239 Vaccination of female DBA/2 mice with CFA/I fimbriae or dscCfaE, each given with a genetically atten

240 Unlike fimbriae or LT, STa has not often been included as an an

241 Here we studied Salmonella atypical fimbriae (or Saf pili), formed by the conserved chaperon

242 E. coli fimbriae, or colonization factor antigens (CFAs), and en

243 Adherence, often mediated by fimbriae, permits bacteria to attach to host cells and e

244 ssing fimbriae (phase ON) and not expressing fimbriae (phase OFF).

245 vidual bacterium switches between expressing fimbriae (phase ON) and not expressing fimbriae (phase O

246 xpresses a plethora of colonization factors (fimbriae/pili), of which CFA/I and CFA/II, which are ass

247 Adhesion pili (fimbriae) play a critical role in initiating the events

248 single oral dose of purified, soluble CFA/I fimbriae protected against CIA as effectively as did Sal

249 richia coli colonization factor Ag I (CFA/I) fimbriae protects against collagen-induced arthritis (CI

250 hat native forms of both the major and minor fimbriae proteins bind to and signal through TLR2 for th

251 The major and minor fimbriae proteins produced by the human pathogen Porphyr

252 s vaccine candidates are the usher-chaperone fimbriae Psa and Caf.

253 splaying a surface-located oligosaccharide P fimbriae receptor mimic that bound to P-fimbriated E. co

254 We conclude that synthesis of P fimbriae regulates flagellum synthesis to repress motili

255 s provide a comprehensive analysis of type 1 fimbriae regulation in ST131, and highlight important di

256 While constitutive expression of type 1 fimbriae resulted in a significant decrease in motility

257 Fimbriae share a common mode of biogenesis, orchestrated

258 Thus, CFA/I fimbriae stimulate IL-35 required for the coinduction of

259 the association of FimCDE with P. gingivalis fimbriae suggest that FimE may recruit FimC and FimD int

260 . coli body is surrounded by many long, thin fimbriae terminating in a single FimH receptor that is c

261 were caused by strains less likely to have P fimbriae than other rUTI strains (P=.002).

262 ouse periodontitis model and express shorter fimbriae than the wild type.

263 ct models for 2 morphological forms of CFA/I fimbriae that are both observed in vivo: the helical fil

264 antigen (Psa) of Yersinia pestis consists of fimbriae that bind to two receptors: beta1-linked galact

265 Assembly of type 2 fimbriae that directly facilitate coaggregation with ora

266 ve enterobacteria produce surface-associated fimbriae that facilitate attachment and adherence to euc

267 ein polymers on their surface called pili or fimbriae that serve either as attachment devices or as c

268 2 agonists include lipopolysaccharide (LPS), fimbriae, the lipoprotein PG1828, and phosphoceramides.

269 found no role for the aggregative adherence fimbriae, the transcriptional activator AggR, or the sur

270 The binding of purified plasmid-encoded fimbriae to a glycanarray suggested that this adhesin sp

271 Direct binding of the major and minor fimbriae to a human chimeric CD14-Fc protein also establ

272 shed specific binding of the major and minor fimbriae to CD14 with classic saturation kinetics.

273 Binding of purified Std fimbriae to Fucalpha1-2Galbeta1-4GlcNAc in a solid phase

274 its the costly expression of plasmid-encoded fimbriae to host environments in a mouse model.

275 The binding of plasmid-encoded fimbriae to Le(x)-coated wells could be inhibited by co-

276 not observe binding with the major or minor fimbriae to the TLR4-Fc chimeric protein, signaling thro

277 is expresses proteinaceous pili (also called fimbriae) to mediate the following two key events in bio

278 n vivo following adherence, using the type 3 fimbriae, to indwelling devices coated with extracellula

279 ify them into a low-force unwinding group of fimbriae together with the CFA/I and CS20 fimbriae expre

280 ved in this regulation of motility by type 1 fimbriae, transposon mutagenesis was performed on a phas

281 Inquiring into their relevance, CFA/I fimbriae-treated IL-27R-deficient (WSX-1(-/-)) mice were

282 eezers force spectroscopy, we found that CS2 fimbriae unwind at a constant force of 10 pN and have a

283 ncoded mannose-resistant Proteus-like (MR/P) fimbriae, urease, iron uptake systems, amino acid and pe

284 We show here that CFA/I fimbriae utilize donor strand complementation to promote

285 cted ExPEC virulence genes, including pap (P fimbriae), vat (vacuolating toxin), kpsM II (group 2 cap

286 only by UPEC, and (3) dependent upon type 1 fimbriae, we analyzed strains representing epidemiologic

287 After verifying biosynthesis of the chimeric fimbriae, we examined their binding specificities in bac

288 Mad fimbriae were detected on TT01 phase ON cells but not on

289 Fimbriae were downregulated in swarming cells, while gen

290 Ygi fimbriae were necessary for wild-type levels of adherenc

291 Yad fimbriae were necessary for wild-type levels of adherenc

292 The Mad fimbriae were not required for insect pathogenesis, indi

293 Plasmid-encoded fimbriae were purified from the surface of E. coli, and

294 flagellar motility and expression of type 1 fimbriae were unimportant.

295 When whole fimbriae were used, the antifimbrial immune serum that c

296 control E. coli strain, which lack of type 1 fimbriae, were ineffective.

297 This is accomplished through its surface fimbriae, which induce CXCR4/TLR2 co-association in lipi

298 , the shaft fimbrillin of Actinomyces type 2 fimbriae, which uniquely mediates the receptor-dependent

299 eversible and abolished by pre-incubation of fimbriae with anti-CfaE antibody.

300 Interaction of Mfa fimbriae with S. gordonii is necessary to initiate signa