ライフサイエンスコーパス: fine-tuning

1 eptor trafficking, targeting, and functional fine-tuning.

2 near the two ends of the chain with minimal fine-tuning.

3 biochemically specific method of clinically fine-tuning abiraterone metabolism to optimize therapy.

4 The promise of selectively "fine-tuning" acoustic mapping as it emerges has far-reac

5 erebellum by patterning the molecular zones, fine-tuning afferent circuitry, and shaping neuronal act

6 nhibition during a period of neurobehavioral fine-tuning (age 22-36 years).

7 f the synaptic proteasome is responsible for fine tuning AMPA receptor synaptic levels under basal co

8 affecting expression) accomplish wide-spread fine tuning and both jointly contribute to the functiona

9 ial band-pass structures that do not require fine-tuning and are robust against environmental and cel

10 to-eukaryote transition allows for increased fine-tuning and broadening of Hsp70 function in eukaryot

11 ay represent a more widespread mechanism for fine-tuning and optimization of cellular immunity.

12 This one-component feature allows for fine-tuning and optimization of the drug loading and phy

13 ows that microRNAs play an essential role in fine-tuning and providing robustness to the switch.

14 However, fine-tuning and termination of TCR signaling are only pa

15 ponsive genes and discuss their relevance in fine-tuning antimicrobial immune responses.

16 logical plasticity mechanism for dynamically fine-tuning AP conduction velocity, which potentially ha

17 rization may serve as a unique mechanism for fine-tuning APJ-mediated functions.

18 obably determined by hydrophobicity, but the fine tuning appears to arise from the distribution of ca

19 as been described, these processes and their fine-tuning are not fully understood.

20 might be important for low firing rates and fine-tuning basal dopamine levels, while switching excit

21 ng interfaces are not the result of adaptive fine tuning but a simple consequence of random genetic d

22 rings, alkyl groups, and halogens allowed a fine-tuning capability to the hydrophobic character and

23 s identified as the underlying mechanism for fine-tuning carotenoid composition, stability, and ultim

24 Thus, MCJ offers a mechanism for fine-tuning CD8(+) T cell mitochondrial metabolism as an

25 and CaMKI and PME-1 networks may function in fine-tuning cell proliferation and stress response.

26 by remodeling their local microenvironment, fine-tuning cell stiffness, polarity, and shape.

27 her receptors is emerging as a mechanism for fine-tuning cellular responses.

28 and highly conserved role for the BBSome in fine-tuning ciliary signaling by regulating the ciliary

29 tifying and correcting causes of failure and fine-tuning circuit characteristics.

30 ng protein, shedding light to understand the fine-tuning control of the different vesicle fusion even

31 nal modification of steroid receptors allows fine-tuning different properties of this family of prote

32 l specification, the underlying mechanism of fine-tuning double flower formation remains largely uncl

33 y FMRP and FXR2P that ultimately affects its fine-tuning during synaptic activity.

34 Overall, this work suggests that fine-tuning E degrees ' in HCOs and other heme enzymes c

35 nstrate that miR-224 plays a pivotal role in fine tuning enamel mineralization by modulating SLC4A4 a

36 plants to adapt to changing environments by fine-tuning energy production in leaves and the availabi

37 r coactivators may play an important role in fine-tuning ERalpha transactivation.

38 ted immune responses may provide avenues for fine-tuning existing IFN treatment for infection and int

39 Mechanisms of fine-tuning expression of iron-regulated genes, beyond s

40 ltiple genes, often within the same pathway, fine-tuning expression of key factors and stabilizing ge

41 esults suggest that the cerebellum's role in fine-tuning eye movements extends even to the oculomotor

42 However, the machinery fine-tuning FGFR signaling in chondrocytes is incomplete

43 However, predictably fine-tuning function (e.g., by adjusting ligand affinity

44 Astrocytes are crucial in the formation, fine-tuning, function and plasticity of neural circuits

45 e HNF1B-mediated transcription necessary for fine tuning FXYD2 transcription in the DCT and suggest t

46 ng site, the Tyr-541 residue participates in fine-tuning Gd(3+)-sensitivity, and that the Asn-584 res

47 olism may underlie the clinical phenotype by fine tuning gene expression which is essential for corre

48 The role of microRNAs (miRNA) in fine-tuning gene expression has become a major regulator

49 ntegrate such gene-environment interactions, fine-tuning gene expression, and possibly contributing t

50 , have been shown to play important roles in fine-tuning gene expression, defending virus and control

51 ntrabodies and provide a novel framework for fine-tuning GPCR functions with potential therapeutic im

52 ntroduces a hybrid approach for creating and fine tuning high-Q nanocavities, involving the local dep

53 se to environmental signals, is critical for fine-tuning HlyA cytotoxicity.

54 miRNAs play an important role in fine-tuning host immune homeostasis and responses throug

55 Thus, HBL1 plays a modulatory role in fine-tuning human-specific cardiomyocyte development by

56 cate an interplay between STAT1 and STAT3 in fine-tuning IL-21 actions.

57 d ligand interaction, as well as its role in fine tuning immune cell functions and its clinical relev

58 udy identifies a novel role for microRNAs in fine-tuning immune homeostasis and thereby maintaining t

59 ment for numerous optical elements and their fine tuning in conventional design, paving the way for r

60 c connectors for the catalytic sites with no fine tuning in DeltaEm_b required for efficient cross-me

61 d their crystalline mechanical properties to fine-tuning in a controllable manner by disrupting the w

62 verse metal or complex cations, resulting in fine-tuning in porosity, fast ion conductivity, and phot

63 ur study shows that exosomes are involved in fine-tuning intercellular communication in asthma.

64 In plant primary metabolism, metabolic fine-tuning involves feed-back mechanisms whereby the ou

65 This fine-tuning is controlled by the nuclear receptors (NRs)

66 astic energy at different temperatures, thus fine-tuning its core replacement energy to reversibly se

67 ariety of biochemical mechanisms employed in fine-tuning its redox properties and function.

68 core promoter region plays a central role in fine-tuning levels of capsule to promote colonization an

69 and allelic expression control necessary for fine-tuning mammalian immune responses.

70 lation of BMP signal transduction provides a fine-tuning mechanism based on the two major enzymes tha

71 te that O-GlcNAcylation of DELLAs provides a fine-tuning mechanism in coordinating multiple signaling

72 o study models of MOND and to illustrate the fine-tuning mechanism in cosmology.

73 Although the fine-tuning mechanism provided by A-to-I RNA editing is

74 nd WRN, suggesting that PARylation acts as a fine-tuning mechanism to coordinate their functions in t

75 motility, we propose a novel CRISP1-mediated fine-tuning mechanism to regulate sperm hyperactivation

76 by IHF and Fis, while CRP seems to provide a fine-tuning mechanism.

77 tro and in vivo data in order to help define fine-tuning mechanisms at four sensitive receptor popula

78 r results indicate that SRT2 is important in fine-tuning mitochondrial energy metabolism.

79 regulation by miR-34a provides one means of fine-tuning Mo behavior toward AC in specific tissue env

80 s of core components have implicated PRC2 in fine-tuning multiple pathways that instruct HSPC behavio

81 Fine-tuning Myc matters and is possible as Myc protein h

82 y loop and converter domain is important for fine-tuning myosin kinetics, in particular ATP binding a

83 inhibiting extrasynaptic NMDARs and thereby fine tuning neuronal excitability and signaling.

84 sis, thereby providing a local mechanism for fine-tuning neuronal excitability.

85 supports host protection during infection by fine-tuning NF-kappaB activity, suggesting that SP110b m

86 d in vivo, and identify a ZNRF4-RIP2 axis of fine-tuning NOD2 signalling to promote protective host i

87 We report that this fine tuning of ATP and O2(.-) levels by cooling controls

88 rial function that negatively impacts on the fine tuning of Ca(2+) dynamics.

89 Thus, the fine tuning of Ca(2+) signals plays a key role in shapin

90 Fine tuning of conditions will be needed for other amino

91 recognition and metabolizing activities for fine tuning of DNA repair processes.

92 We conclude that a fine tuning of ERK1/2 signaling strength is critically i

93 nominal M n+1AX n compounds enables not only fine tuning of existing properties but also entirely new

94 This may contribute to the fine tuning of expression of the denitrification respiro

95 This fine tuning of GAL1/glycan interactions may be a strateg

96 nd AtPMEI7 could be partners involved in the fine tuning of HG methylesterification during plant deve

97 The fine tuning of metabolism and hERG followed by different

98 n underscores the importance of SLC25A46 and fine tuning of mitochondrial fission and fusion in ponto

99 the tissue-specific regulation of OXPHOS and fine tuning of mitochondrial translation accuracy.

100 ranscription factors and coregulators in the fine tuning of organismal metabolism.HDAC3 is a critical

101 en ITAM and RANK/TNFR signaling and allowing fine tuning of osteoclastogenesis during bone homeostasi

102 echanism refined by evolution to allow for a fine tuning of p38alpha kinase activity.

103 unique, quantized activation process enables fine tuning of PANX1 channel activity and may be a gener

104 ays between pump and probe pulses allows for fine tuning of spectral resolution, bandwidth and imagin

105 epresent molecular tools for transcriptional fine tuning of target genes.

106 Thus, the fine tuning of TGFbeta signalling derives from positive

107 bond-breaking elementary steps and thus the fine tuning of the biological repair function for optima

108 ls whose synthesis critically depends on the fine tuning of the crystal growth and error correction r

109 Fine tuning of the emission characteristics through stru

110 of a Nedd8-moiety to Cullin proteins) in the fine tuning of the NF-kappaB response (via Cullin-1).

111 (usually life history) time frames, offering fine tuning of the response to environmental context.

112 the cell membrane, their activation and the fine tuning of their biophysical properties are all dram

113 This allows for the fine tuning of their optical and electrochemical propert

114 lar body and repair of adult tissues require fine--tuning of cell adhesion, cell mechanics, and inter

115 DCs, the action of which contributes to the fine-tuning of Ag cross-presentation.

116 e for mounting novel responses and decreased fine-tuning of BCR specificities by somatic hypermutatio

117 Our results show that fine-tuning of BCR-ligand recognition can lead to B cell

118 ur data suggest that PIST contributes to the fine-tuning of beta1AR sorting both during biosynthetic

119 We show a strict fine-tuning of binding and sequence-dependent alteration

120 to damaged chromatin, ZMYM3 facilitates the fine-tuning of BRCA1 interactions with DNA damage sites

121 This vital function is based on the fine-tuning of cardiac performance by the Frank-Starling

122 Such location sensitivity may reflect fine-tuning of category-specific visual processing to re

123 are water channel proteins that mediate the fine-tuning of cell membrane water permeability during d

124 material properties of the cell wall and the fine-tuning of cellular biophysical parameters in the mu

125 of KSRP destabilizes CX3CL1 mRNA, providing fine-tuning of cellular inflammatory reactions in respon

126 TIP isoforms allow the spatial and temporal fine-tuning of cellular water transport, which is critic

127 eful properties that can be tailored through fine-tuning of certain parameters, such as size, shape a

128 the Weyl semimetal state does not depend on fine-tuning of chemical composition or magnetic order, w

129 ase pathways and drug exposure, allowing for fine-tuning of clearance in response to specific conditi

130 Finally, we propose that precise fine-tuning of conduction along already-myelinated axons

131 and Arp2/3 and suggest a mechanism for rapid fine-tuning of cortex structure and mechanics by adjusti

132 Fine-tuning of cytokine-inducing pathways is essential f

133 calization and activity, suggesting that the fine-tuning of DA homeostasis involves multiple mechanis

134 ating that m(6)t(6)A plays a general role in fine-tuning of decoding in organisms from bacteria to ma

135 al stresses that require the involvement and fine-tuning of different stress signaling pathways.

136 Fine-tuning of electron-poor aromatic rings in position

137 n which structural changes are necessary for fine-tuning of electronic properties.

138 based EWNS platform was developed to enable fine-tuning of EWNS properties by modifying synthesis pa

139 and increase efficiency of neural function, fine-tuning of excitatory and inhibitory neurotransmitte

140 These adjustments involve fine-tuning of expression levels and mutual interactions

141 our results demonstrate for the first time a fine-tuning of FACT by a ubiquitin proteasome system in

142 LC-SOC1 signaling network contributes to the fine-tuning of flowering during changing seasons.

143 ent advances in the design, preparation, and fine-tuning of fluorophores by means of multicomponent r

144 MicroRNA is responsible for the fine-tuning of fundamental cellular activities and human

145 , in particular microRNAs (miRNAs), regulate fine-tuning of gene expression and can impact a wide ran

146 in function of m(6)A is post-transcriptional fine-tuning of gene expression.

147 mRNA decay mechanisms suggests selection for fine-tuning of gene expression.

148 uf3p plays a broad, but nuanced, role in the fine-tuning of gene expression.

149 criptional regulation of RNA facilitates the fine-tuning of gene expression.

150 A-mediated feedback and feedforward loops in fine-tuning of gene expression; (ii) the miRNA-target in

151 The results show that conformational fine-tuning of helical pore-forming peptides is a powerf

152 Thus, we have discovered that fine-tuning of HlyA expression by the CpxRA system is cr

153 , cell trafficking to sites of inflammation, fine-tuning of immune responses leading to activation or

154 ral circuits, which often requires exquisite fine-tuning of inhibitory connections.

155 topes on the same target molecule may enable fine-tuning of intracellular delivery based on the hemod

156 that this expansion of the JAZ family allows fine-tuning of JA-mediated transcriptional responses.

157 to regulation at multiple levels that allow fine-tuning of key biological responses.

158 ively stimulate abortive termination without fine-tuning of kinetic rate parameters at ribosome stall

159 NHCs and provides a guide to the structural fine-tuning of ligand requirements and stereochemical mo

160 Tissue modulation is dependent on the fine-tuning of mechanical forces that are transmitted in

161 he body of work on the synthesis and optical fine-tuning of meso-aryl-substituted bacteriochlorins.

162 ation by promoting Tnfaip3 transcription and fine-tuning of metabolic reprogramming in macrophages.

163 for a variety of processes, ranging from the fine-tuning of motor skill learning to important social

164 tive valorisation of lignin requires careful fine-tuning of multiple "upstream" (i.e., lignin bioengi

165 s that MYB182 plays an important role in the fine-tuning of MYB134-mediated flavonoid metabolism.

166 s without requiring any form of learning, or fine-tuning of neuronal parameters to replicate these re

167 in this compound correlates closely with the fine-tuning of one of the band-edge singularities to wit

168 ensures site-specific NCP ubiquitination and fine-tuning of opposing enzymatic activities.

169 The fine-tuning of optical and switching properties relies o

170 s to realize MF, however, generally requires fine-tuning of parameters.

171 nctional conformations, this enzyme exerts a fine-tuning of phosphorylation signals.

172 icity and anisotropy, can further permit the fine-tuning of plasmon behaviors in borophene, potential

173 osine modulation may provide a mechanism for fine-tuning of plasticity and learning according to brai

174 criptome diversification is required for the fine-tuning of protein expression in monocytes, suggesti

175 crutinity of polymerization outcomes and the fine-tuning of reaction conditions.

176 eceptor-interacting proteins also facilitate fine-tuning of receptor activity and tissue specificity.

177 m memory, which is robust to noise and where fine-tuning of recurrent excitation or inclusion of sub-

178 ortant role in accelerating the evolutionary fine-tuning of regulatory networks.

179 rved physiological role for Oma1 protease in fine-tuning of respiratory function.

180 e, to our knowledge, for the first time that fine-tuning of ROS production by RhoA, through a delicat

181 The fine-tuning of stoichiometry and organization is realize

182 l pathways have been suggested to accomplish fine-tuning of stress responses at the expense of growth

183 n many interacting components that allow for fine-tuning of switching and memory properties.

184 central role of AMPARs in neurobiology, the fine-tuning of synaptic AMPA responses by endogenous mod

185 privation, 2-AG signaling may play a role in fine-tuning of synaptic strengths via presynaptically-ex

186 The dynamic fine-tuning of tendon ECM composition and assembly thus

187 al search efficiency but enables rapid local fine-tuning of TF search parameters.

188 e novel mechanism proposes the DDB2-mediated fine-tuning of TGF-beta signaling and its downstream eff

189 screening platform promises to enable rapid fine-tuning of the ABA sensors and engineering of plant

190 ds for RGD-recognizing integrin subtypes; 5) fine-tuning of the affinity and selectivity by additiona

191 Following fine-tuning of the anesthetic regime, stimulation elicit

192 The results showed a fine-tuning of the binding properties of [8]CPP 1 toward

193 n receptor trafficking and signaling for the fine-tuning of the cellular response.

194 In addition, fine-tuning of the crystal structure by changing the cry

195 The fine-tuning of the degree of methylesterification of cel

196 n or peptide-based imaging probes and allows fine-tuning of the desired blood half-life, because long

197 The fine-tuning of the electronic properties and redox poten

198 An easy synthetic approach has enabled the fine-tuning of the electronic structure of the organobor

199 ion of excitation and inhibition and enables fine-tuning of the excitation-inhibition balance.

200 rent solvent systems, as key factors for the fine-tuning of the extraction properties, are discussed.

201 propose a general mechanism that enables the fine-tuning of the Fermi velocity in Dirac materials in

202 r, human LCN2-R-NTD could be involved in the fine-tuning of the interaction between NGAL and its cell

203 l bursting individually allows combinatorial fine-tuning of the level of MHC class I gene expression

204 In conclusion, fine-tuning of the levels of EBOV GP expressed at the su

205 ata suggest that it might be involved in the fine-tuning of the life span and function of activated D

206 bis(diphenylphosphino)amine (DPPA) allows a fine-tuning of the ligand properties and offers a consid

207 ystematic study, we show that the structural fine-tuning of the linkers allows access to variations i

208 Fine-tuning of the maintenance of lysogeny is facilitate

209 y acquisition, possibly allowing more subtle fine-tuning of the maturation process.

210 hes between hydrophilic and hydrophobic, but fine-tuning of the microenvironment is possible by adjus

211 rinciples of mu-EME transfer enabled further fine-tuning of the mu-EME process.

212 hylenediamine kappa pharmacophore allows the fine-tuning of the pharmacodynamic and pharmacokinetic p

213 These modifications allowed for fine-tuning of the photoluminescence (PL) and ECL emissi

214 uch polyplex formulation and determined that fine-tuning of the polyplex structure is essential for e

215 antly, the ligands on the boronate allow for fine-tuning of the properties and reactivity of acylboro

216 This allows a fine-tuning of the properties of these macrocycles throu

217 this deacetylase proteome could lead to the fine-tuning of the regulation of microtubule dynamics an

218 ty of GAIT elements may provide hierarchical fine-tuning of the resolution of inflammation.

219 sition 7 of quinolinone ring combined with a fine-tuning of the substituents on the benzyl group in p

220 be integrated into one single 2.5 nm AuNP by fine-tuning of the surface coverage; a ratiometric pH re

221 s within the IleRS.tRNA complex, whereas the fine-tuning of the synthetic site is attained via confor

222 teroaromatic moiety provided a means for the fine-tuning of the UV/vis absorption and emission spectr

223 Golgi trafficking and thus contribute to the fine-tuning of the water permeability of the plasma memb

224 rsity of their building blocks, which allows fine-tuning of their chemical and physical properties by

225 Our results demonstrate that fine-tuning of their photophysical properties can be obt

226 , plays an important role in the control and fine-tuning of these stress responses.

227 ampal circuits throughout adulthood, and the fine-tuning of this process is likely important for effi

228 Hence, chromatin chaperone-mediated fine-tuning of transcription is crucial for driving morp

229 ssor activity and might be important for the fine-tuning of transcription regulation within this regi

230 offer untapped opportunities for therapeutic fine-tuning of Tregs and their all-important restraint o

231 litate host adaptation through sRNA-mediated fine-tuning of virulence gene expression.

232 nabled model provides insights into thermal "fine-tuning" of carbohydrate metabolism and a warning th

233 s have important implications with regard to fine-tuning our understanding of the bipolar disorder br

234 een recognized, and offers novel avenues for fine-tuning oxide nanocomposites with enhanced functiona

235 at ATFS-1 stimulates respiratory recovery by fine-tuning OXPHOS expression to match the capacity of t

236 type MEFs, suggesting a role for p19(Arf) in fine-tuning p53 activity.

237 le, mediates satellite cell heterogeneity by fine-tuning Pax7 levels during muscle development and re

238 zymatic back-up systems, are responsible for fine-tuning physiological redox signaling.

239 nation-mediated stress-tolerance pathways by fine-tuning Poleta turnover.

240 lung development with epigenetic regulation fine-tuning pre-natal developmental processes.

241 tion, CARD9 negatively regulates IL-1beta by fine-tuning pro-IL-1beta expression, spleen tyrosine kin

242 Here we explore a platform which avoids the fine-tuning problem, namely a ferromagnetic chain deposi

243 plicing of Nf1 is an important mechanism for fine-tuning Ras/ERK signaling as well as learning and me

244 Furthermore, the assay can be used for fine-tuning reaction mixtures of various agents to enhan

245 ing diverse intrinsic and extrinsic signals, fine-tuning regulatory output and increasing the robustn

246 erall, these results provide new insights on fine-tuning RNA binding properties of ametantrone by sin

247 activate, SAMHD1 dNTPase in S phase, thereby fine-tuning SAMHD1 control of dNTP levels during DNA rep

248 This fine tuning seems to occur mainly in the nucleus at the

249 enesis mechanisms, and ICL2 is proposed as a fine-tuning selective switch that can differentiates mod

250 n bond network constitutes a focal point for fine-tuning seven trans-membrane receptor conformations

251 henotyping, we propose target haplotypes for fine-tuning starch structure in rice through marker-assi

252 ongly correlated regime and does not require fine tuning, suggesting that this state is generic for p

253 verse signaling is an autocrine feedback and fine-tuning system in the communication between cells th

254 Through such fine-tuning, target selection and downstream effects of

255 lling evidence for a new function of BRD7 in fine-tuning TGF-beta physiological responses.

256 ivalent approach may provide a mechanism for fine tuning the efficacy of allosteric compounds in futu

257 ted by the ubiquitin ligase Neuralized, thus fine tuning the endocytosis and activity of this apical

258 egulate homeostasis in health and disease by fine tuning the expression of a network of genes through

259 we explore the mechanism of mCA and MeCP2 in fine tuning the expression of long genes.

260 ntermediates provides an important valve for fine tuning the pathway flux.

261 During ZnO growth, fine tuning the solution temperature expedites random cu

262 novel BF-3 regulatory sequence important for fine-tuning the activity of the AR.

263 lm morphologies (continuous large grains) by fine-tuning the amount of surface ligands used.

264 Thus miRNAs are important for fine-tuning the atrophy program and their modulation can

265 potential role for a 'housekeeping' gene in fine-tuning the development of an ecologically important

266 This would allow fine-tuning the dosage according to the patient's metabo

267 These findings provide a new approach for fine-tuning the electronic properties of peptides by con

268 ycling-independent iron uptake in hBMVECs by fine-tuning the endosomal pH in response to paracrine si

269 native differentiation possibilities through fine-tuning the expression of a critical epigenetic regu

270 more, we found that Setdb2 functions through fine-tuning the expression of dvr1, a ligand of the TGF-

271 ugh a feedback loop that might contribute to fine-tuning the expression of more than a thousand of MY

272 hrough modulating the production of H2 O2 by fine-tuning the expression of poxL, indicating that H2 O

273 global regulators of developmental timing by fine-tuning the expression of temporal regulatory genes.

274 urther demonstrate the general importance of fine-tuning the integrative properties of neuronal dendr

275 pe mice, suggesting Adn has multiple effects fine-tuning the kinetics of liver regeneration.

276 ing unit, we suggest that these proteins are fine-tuning the last steps of CPS biosynthesis (i.e. the

277 rol the mitochondrial apoptotic machinery by fine-tuning the levels of expression of the proapoptotic

278 bility of cells to trap and transduce BMP by fine-tuning the levels of the BMP reception system at th

279 hese thinner high-quality SAPO-34 membranes, fine-tuning the local crystal structure by incorporating

280 M-CSFR signaling played an important role in fine-tuning the MHC-II(hi) phenotype.

281 mbinations of promoter motifs are engaged in fine-tuning the MTI response and active transcriptional

282 with G1 progression may thus be critical for fine-tuning the orientation of the polarity axis in yeas

283 iding adjustable drug activation kinetics by fine-tuning the peptide interface layer.

284 protection or protein repair processes, thus fine-tuning the photosynthetic energy conversion.

285 We also show that fine-tuning the predictor on a set of well-studied 'gold

286 ategy allowed us to establish principles for fine-tuning the properties of fluorophores and to develo

287 teractions also presents a convenient way of fine-tuning the protein's interaction network, by making

288 lity of cortisol in inflamed environments by fine-tuning the RCL proteolysis by endogenous and exogen

289 gence in product selectivity was achieved by fine-tuning the steric nature of the ligand of the Au(I)

290 the S1 helix also play an important role in fine-tuning the voltage dependence of activation, regula

291 anoparticle superstructures is important for fine-tuning their chiroptical properties.

292 structural variations of small molecules for fine-tuning their electronic properties, such as ionizat

293 gence in T cells' effector phenotypes, hence fine-tuning their functioning.

294 mains of many ion channels are important for fine-tuning their gating kinetics.

295 a nexus for sleep and mood regulation while fine-tuning these processes to adapt to seasonal changes

296 for mammalian cells often require extensive fine-tuning to perform as intended.

297 that CLEC14A acts in vascular homeostasis by fine-tuning VEGFR-2 and VEGFR-3 signaling in ECs, sugges

298 nstream of PINK1 and HTRA2 for mitochondrial fine tuning, whereas TRAP1 loss of function leads to red

299 y factor in the execution of transcriptional fine-tuning with Mbd3/NuRD in ESCs through interactions

300 We propose that this level of fine-tuning within MYO1C broadens its adaptability withi