ライフサイエンスコーパス: firing frequency

1 g is restored, although at a greatly reduced firing frequency.

2 re they act to delay excitation and regulate firing frequency.

3 ing a role in the modulation of motor neuron firing frequency.

4 current in these neurons and increased their firing frequency.

5 fects on release depend on the subregion and firing frequency.

6 d may contribute to modulating the circadian firing frequency.

7 activation that correlates with LC neuronal firing frequency.

8 hat I(h) plays a critical role in modulating firing frequency.

9 tentials that became more pronounced at high firing frequency.

10 o release Ca(2+) is modulated by its average firing frequency.

11 ts in which subthreshold I(A) might regulate firing frequency.

12 t from a ceiling effect on projection neuron firing frequency.

13 ials of the AVN cells and an increase in the firing frequency.

14 ndent on the strength of coupling but not on firing frequency.

15 emaker, neurons show circadian variations in firing frequency.

16 eform shape and duration, firing pattern and firing frequency.

17 ate nucleus (dLGN) is markedly enhanced with firing frequency.

18 aden action potentials and lower sustainable firing frequency.

19 and plays an important role in setting tonic firing frequency.

20 eby depolarizing the cell and increasing its firing frequency.

21 nd was associated with a reduction in evoked firing frequency.

22 activation at subthreshold voltages modulate firing frequency.

23 and its release probability is dependent on firing frequency.

24 cells was able to increase the intrinsic IHC firing frequency.

25 e inactivating K+ channels to modulate their firing frequency.

26 which in turn was followed by an increase in firing frequency.

27 hat it increases with increasing motorneuron firing frequency.

28 nward depolarizing current and increased the firing frequency.

29 s, and block by 1 mM cesium had no effect on firing frequency.

30 ion evoked by Ba2+ or CRH increased the cell firing frequency.

31 may be a key factor in determining neuronal firing frequency.

32 l sympathetic nerve fibers rather than their firing frequency.

33 sing action potential threshold and lowering firing frequency.

34 cells was able to increase the intrinsic IHC firing frequency.

35 pike in a train, without reducing subsequent firing frequency.

36 ppresses glucose-stimulated action potential firing frequency.

37 , this was associated with increased initial firing frequency.

38 ncreased action potential (AP) amplitude and firing frequency.

39 rower action potentials and a higher maximal firing frequency.

40 amin was found inversely correlated to basal firing frequency.

41 and observed a CB(2)R-mediated reduction in firing frequency.

42 fferentiation 4 (CD4)), enhanced spontaneous firing frequency.

43 tly less effective at increasing the maximal firing frequency.

44 on decreased current threshold and increased firing-frequency.

45 ng interneuron pairs through a wide range of firing frequencies.

46 ork state and only mildly attenuated by high firing frequencies.

47 neurons typically display much lower maximum firing frequencies.

48 inactivation that is active at physiological firing frequencies.

49 apses permits iBMPs to be initiated at lower firing frequencies.

50 lity of transmission across a broad range of firing frequencies.

51 rates, but have little contribution at lower firing frequencies.

52 ion, leading to spike broadening at moderate firing frequencies.

53 ter approximately 45 impulses, regardless of firing frequency (1-10 Hz), and autonomous activity decl

54 The MVC(like) SPNs have higher baseline firing frequencies (2.52 +/- 0.33 Hz vs. CVC(like) 1.34

55 action potentials (4.2 +/- 1.4 ms) and high firing frequencies (68.9 +/- 5.3 Hz), both sensitive to

56 , a progressive reduction in Purkinje neuron firing frequency accompanies cell atrophy.

57 n the GP may echo the changes in presynaptic firing frequency across postsynaptic targets.

58 ce, impedance amplitude and action-potential firing frequency across the somato-apical trunk.

59 Measuring firing frequency alone only partially reflects spike pat

60 litude of the HOpr; instead, they affect the firing frequency among individual cell cycles.

61 ltured mouse DRG neurons and increased their firing frequency, an effect that was absent in DRG neuro

62 Decreases in the firing frequencies and burst durations that were thresho

63 to neural activation, the relations between firing frequencies and forces developed by the muscles.

64 A range of firing frequencies and patterns was observed including r

65 different neuronal responses with different firing frequencies and temporal dynamics.

66 t thermal stimuli markedly increase the mean firing frequencies and the number of active rat DRG neur

67 ls, neurons need to achieve a broad range of firing frequencies and to move smoothly between low and

68 w presynaptic terminals to translate complex firing frequencies and tune the amount of neurotransmitt

69 pes leads to an increase in action potential firing frequency and a rise in the intracellular Ca(2+)

70 Furthermore, AUT1 application modulated firing frequency and action potential properties of Cloc

71 afterhyperpolarization (AHP) that influences firing frequency and affects neuronal integration.

72 midbrain neurons, menthol reduced DA neuron firing frequency and altered DA neuron excitability foll

73 enhanced inhibitory transmission reduced the firing frequency and altered the pattern of action poten

74 enlarged glucagon granules and increased AP firing frequency and amplitude coinciding with enhanced

75 bilaterally resulted in reductions of their firing frequency and amplitude of inspiratory-related sy

76 OC) and I(SK), leading to an increase in the firing frequency and Ca(2+) influx after a transient ces

77 a role in regulating membrane potential and firing frequency and comprise the target channel mediati

78 wild-type mice, facilitation increases with firing frequency and counteracts depression to produce f

79 thalamic brain slices, sevoflurane inhibited firing frequency and delayed the onset of action potenti

80 s, Maxi-K and M-current, causing enhanced AP firing frequency and depolarization, respectively.

81 Neuronal firing frequency and duration determine the time course

82 entials, but F1.Q54 neurons exhibited higher firing frequency and greater evoked activity compared wi

83 I(SA)s) are important in regulating neuronal firing frequency and in the modulation of incoming signa

84 sitivity was indicated by augmentation of AP firing frequency and increased maximum gain of AP freque

85 ke receptor blockade reduced SNr GABA neuron firing frequency and increased their firing irregularity

86 larizing inputs and the relationship between firing frequency and input (f-I curve), each of which is

87 highly sensitive to multiple factors such as firing frequency and membrane conductance, raising doubt

88 neuroanatomical observations (e.g., average firing frequency and number of neurons).

89 and may result in persistent changes to both firing frequency and pattern.

90 tion, mAChR activation consistently enhanced firing frequency and produced large, sustained afterdepo

91 currents of 20-30 pA increase instantaneous firing frequency and reset the phase of spontaneously fi

92 nts in sodium channel Na(V)1.7 that increase firing frequency and spontaneous firing of dorsal root g

93 nd of the physiological range of motorneuron firing frequency and that it increases with increasing m

94 A-type potassium channels regulate neuronal firing frequency and the back-propagation of action pote

95 reversibly hyperpolarised, and decreased the firing frequency and the input resistance of Im cells vi

96 ); however, there was no correlation between firing frequency and the response to ACh.

97 ential, reduced current-threshold, increased firing-frequency and spontaneous firing.

98 ntain constant strength over a wide range of firing frequencies, and as a result efficiently encode f

99 ond endocytic form is activated by increased firing frequencies, and is selectively blocked by cyclos

100 .g., fast and medium afterhyperpolarization, firing frequency, and depolarizing sag), whereas the dif

101 n of FS outputs is relatively insensitive to firing frequency, and dynamic-clamp experiments reveal t

102 roM) decreased neuronal input resistance and firing frequency, and elicited a steady outward current

103 s characterized by depolarization, increased firing frequency, and increased burst-firing activity.

104 hannels induces hyperpolarization, decreases firing frequency, and increases firing irregularity.

105 d changes in action potential (AP) waveform, firing frequency, and intrinsic excitability.

106 regulating cardiac repolarization, neuronal firing frequency, and neoplastic cell growth.

107 d DA signals varied with the average ongoing firing frequency, and the ratio was generally higher in

108 7mV, increased current-threshold, decreased firing-frequency, and reduced NMDG-induced-hyperpolariza

109 the combination of electrotonic coupling and firing frequency are the key elements that regulate sync

110 stimulus concentration often saturating the firing frequency at 200-300 Hz.

111 t neurons, exhibited a transient increase in firing frequency at a constant interval after the cornea

112 At the normal average firing frequency, burst stimulation produces a larger in

113 ) accumulations that are linearly related to firing frequency but spatially confined to proximal dend

114 oduced more action potentials and had higher firing frequencies, but individual postsynaptic potentia

115 CA3 pyramidal cells and a reduction of their firing frequency, but not by alteration of inhibitory ne

116 ority of dPAG and vPAG units increased their firing frequency, but spike-triggered averaging showed t

117 s depolarizing current pulses) and increased firing frequency by 19% in tonic PGN.

118 in Kv2.1(-/-) mouse beta-cells increased AP firing frequency by 39.6% but did not significantly enha

119 Inhibition of SK channels decreased AP firing frequency by 66% and increased AP duration by 67%

120 arly, isoprenaline increased the spontaneous firing frequency by an effect exclusively on the after-h

121 ontaneously firing cells, ZD7288 reduced the firing frequency by selectively altering the time course

122 Decreased firing frequency can occur via increased function of K+

123 he task (delay), many units showed sustained firing frequency change, either excitation or inhibition

124 arization, brief refractory period, and high firing frequency characteristic of FS GABAergic interneu

125 izing-shift-like complexes, and an increased firing frequency, consistent with a dominant gain-of-fun

126 Furthermore, the CT firing frequency correlated with hedonic ratings to the

127 ve effect, reducing the slope or gain of the firing frequency-current (f-I) relationship.

128 Conversely, increasing the firing frequency decreased the amplitude and synchrony o

129 ons in lesioned cortex had increased maximum firing frequency, decreased initial afterhyperpolarizati

130 uency of miniature IPSCs and the basket cell firing frequency did not differ between groups.

131 Both GPi and GPe firing frequencies differed significantly with dystonia

132 crease burst duration and maximum intraburst firing frequencies during crawling-like motor patterns i

133 bag1 (b1) contacts in addition showed higher firing frequencies during muscle lengthening in active t

134 ing their VCN-elicited activity patterns and firing frequencies, elicited a VCN-like gastric mill rhy

135 : (1) thin axons are most numerous; (2) mean firing frequencies, estimated for nine of the identified

136 e membrane depolarization and enhancement of firing frequency evoked by CRH.

137 ed inspiratory currents but had no effect on firing frequency evoked by unfiltered currents.

138 discharge was termed either anticipated, if firing frequency exhibited classic negative-feedback res

139 Decreases in the PC firing frequency first showed at 6 weeks and paralleled

140 d with an increase in the minimal repetitive firing frequency (Fmin).

141 isting of an acute desensitizing increase in firing frequency followed by a sustained increase that l

142 ttern accurately predicted the difference in firing frequency for secondary afferents obtained by sub

143 llowed by a variable decay to a steady-state firing frequency (Fss).

144 hanges in membrane potential and spontaneous firing frequency have been observed in microbial systems

145 distension-responsive colon afferents: high-firing frequency (HF) and low-firing frequency (LF) cell

146 ls in the PrL, and DP regions had interspike firing frequencies (IFFs) at beta (20-30 Hz) frequencies

147 This oscillator generated firing frequencies in a variable band of 3-12 Hz dependi

148 dentified a SN-selective increase of in vivo firing frequencies in DA midbrain neurons, which was not

149 necessary to attain physiologically relevant firing frequencies in GCs.

150 interneurons demonstrated decreased maximum firing frequencies in malformed cortex compared to contr

151 erents from Kcnq3(-/-) mice showed increased firing frequencies in response to mechanical ramp-and-ho

152 er MC4R PVN neurons, with fasting increasing firing frequency in a leptin-dependent manner.

153 producing depolarization and an increase in firing frequency in epileptic but not control mice.

154 Furthermore, ProTx II decreased firing frequency in human DRGs with spontaneous action p

155 locity but markedly reduced action potential firing frequency in intracardiac neurons, confirming a f

156 s an important modulator of action potential firing frequency in many excitable cells.

157 ssium channels are important determinants of firing frequency in many excitable cells.

158 and a dramatic reduction of action potential firing frequency in rat sympathetic neurons.

159 of the sampled neurons displayed a decreased firing frequency in response to elevated glucose concent

160 or characterized by a continuous decrease in firing frequency in response to hyperpolarizing currents

161 to undergo POMC depolarization or increased firing frequency in response to leptin.

162 gonist phenylephrine increased instantaneous firing frequency in responses evoked by square-wave or l

163 Decreasing the firing frequency in slices from adult animals facilitate

164 ncrease EPSC amplitudes on a linear scale to firing frequency in the physiological range.

165 ha,beta-meATP induced a moderate decrease in firing frequency in three of seven CT preparations.

166 sting that some other conductance influences firing frequency in type A photoreceptors.

167 activation of neurons and precise control of firing frequency in vivo.

168 aded increases in MSNA.In single units, mean firing frequency increased from 0.2+/-0.04 in 21% O2 to

169 s, spikes occurred with long latency and the firing frequency increased throughout the duration of th

170 taneously oscillating action potentials; the firing frequency increased with beta-adrenergic stimulat

171 Similarly, firing frequency increases with intensity and duration i

172 ls of intracellular calcium, which occurs as firing frequency increases, significantly increases the

173 As determinants of spike timing and firing frequency, intracellular Ca(2+) buffers shift the

174 than type B photoreceptors; after this time, firing frequency is higher in type B than type A photore

175 ession, weakening to a greater extent as the firing frequency is increased.

176 a strong, alpha3beta4-dependent increase in firing frequency is observed in these pacemaker neurons

177 oding, in which information is coded through firing frequency, is exemplarily illustrated by place ce

178 plitude, but not spontaneous or odor-induced firing frequency, is under clock control in ab1 and ab3

179 e neurons that also accounts for the reduced firing frequency late in disease.

180 The spontaneous firing frequency lay in the middle of the dynamic range

181 fferents: high-firing frequency (HF) and low-firing frequency (LF) cells.

182 in single boutons at very high instantaneous firing frequencies (more than 700 Hz).

183 can reach a bistable region, between the low firing frequency network state (L) and a quiescent one (

184 ches between receptor and agonist, peaked at firing frequencies of approximately 40 Hz, initiated and

185 rong feedforward inhibition at physiological firing frequencies of dentate granule cells.

186 Such units had a mean firing frequency of 1.62 +/- 0.70 Hz.

187 Stimulating CBI-2 at a physiological firing frequency of 10 Hz for 30 sec causes these synaps

188 ctions, which induced firing up to a maximum firing frequency of 310 Hz.

189 ection evoked regular activity up to maximum firing frequency of 350 Hz followed by moderate spike fr

190 nfusions into VLS also caused changes in the firing frequency of a majority of SNpr neurons.

191 r output rises and falls in concert with the firing frequency of all A-IFM fibers and cannot be expla

192 evoked (in vitro) and spontaneous (in vivo) firing frequency of CA1 neurons, implicating the BK chan

193 Firing frequency of CCK BCs was controlled through M3 mA

194 2 in the CA1 area specifically increases the firing frequency of CCK-positive but not parvalbumin-pos

195 at are seen in patients, including decreased firing frequency of cerebellar Purkinje cells and a decl

196 Although the firing frequency of CINs was increased by blocking gluta

197 Nicotine administration increased the firing frequency of dopamine neurons and specifically in

198 mouse brain slices, RO5203648 increased the firing frequency of dopaminergic and serotonergic neuron

199 sensitivity to light touch and decreases the firing frequency of ectopic discharges originating in Ab

200 , decreases current threshold, and increases firing frequency of evoked action potentials within smal

201 decrease current threshold and increase the firing frequency of evoked action potentials within smal

202 rations, ranolazine reduced action potential firing frequency of hippocampal neurons in response to r

203 tration did not significantly potentiate the firing frequency of individual ARC POMC-EGFP cells compa

204 ow that this mechanosensitivity enhances the firing frequency of individual neurons when they are wea

205 phosphorylation of Kv3.2 lowered the maximum firing frequency of inhibitory neurons, which in turn ne

206 ent had no impact on evoked action potential firing frequency of interneurons, but did suppress aberr

207 ions produced a significant reduction in the firing frequency of L/M interneurons recorded in current

208 om AOB slices, we show that NA decreases the firing frequency of M/TCs in response to stimulation.

209 ogue exendin-4 increase the action potential firing frequency of MCs by decreasing the interburst int

210 nitored by the olfactory bulb can modify the firing frequency of MCs, olfactory coding could change d

211 cokinetic properties, for its effects on the firing frequency of monoaminergic neurons ex vivo, and f

212 synaptic currents will vary depending on the firing frequency of mossy fiber afferents.

213 GLP-1 increases the firing frequency of neurons (mitral cells) that encode o

214 o 63% of that for WT channels, and increased firing frequency of neurons when stimulated with suprath

215 Notably, the firing frequency of Purkinje cells returned to normal ev

216 modulates AHP amplitude, and influences the firing frequency of pyramidal neurones.

217 caine increases both the pacemaker and burst-firing frequency of rat ventral-midbrain dopaminergic ne

218 The slow afterhyperpolarization limits the firing frequency of repetitive action potentials (spike-

219 hat block of Ih differentially increased the firing frequency of spikes occurring early in the train

220 Although noise also increased the firing frequency of the motoneurones slightly, the effec

221 Thus, both firing frequency of the neurons in a circuit, and the mo

222 hibition is inversely related to the initial firing frequency of these cells within their normal rang

223 nd bradykinin) results in an increase in the firing frequency of vagal afferent neurons from <0.1 to

224 otine can directly and robustly increase the firing frequency of VTA DAergic neurons for several minu

225 lockade were accompanied by decreases in the firing frequency of VTA dopamine neurons, an important e

226 dies examining the effects of restoration of firing frequency on motor function and prevention of fut

227 Furthermore, the influence of nRT tonic firing frequency on VB holding current is also greatly r

228 onsequently, LBPP increased mean single-unit firing frequency (P<0.05) and did not inhibit multiunit

229 ecular and neurophysiological (Purkinje cell firing frequency) phenotypes.

230 Mean firing frequencies ranged from 0.06 to 3.65 Hz, with the

231 TRH increased the action potential firing frequency recorded from GABAergic interneurons in

232 followed by a reduction in action potential firing frequency recorded from GABAergic interneurons, s

233 itability by decreasing and increasing their firing frequency, respectively.

234 The gammad firing frequency rose very suddenly from zero to a maxim

235 acilitated AP generation, measured as higher firing frequency, shorter EPSP-AP delay in vivo, and sho

236 ditionally, in vitro and in vivo measures of firing frequency show that BK-channel blockade increases

237 The GPi firing frequency showed a positive correlation with 1-ye

238 In the same period, maximal firing frequency significantly increased and doublets an

239 ified in dyskinetic monkeys and its neuronal firing frequency significantly increased in ON L-DOPA dy

240 ertebrate brain nuclei share similarities in firing frequencies, spike shapes, and inhibition by 5HT

241 ti-compartment, multi-channel model exhibits firing frequency, spike width, and latency to first spik

242 ut, the network exhibits an asynchronous low firing frequency state (L).

243 A photoreceptors have a significantly higher firing frequency than type B photoreceptors; after this

244 to the saturation of synaptic drive at high firing frequencies that contributes to rate control in a

245 vermis and hemisphere have high simple spike firing frequencies that precede complex spikes with grea

246 axon, but also determines the instantaneous firing frequency that encodes pain intensity.

247 though membrane potential is correlated with firing frequency, this correlation is much lower in type

248 relationships allowed current amplitudes and firing frequencies to be tuned by varying the concentrat

249 synaptic drive efficiency, and constrain MN firing frequencies to those optimal for muscle contracti

250 urons for temperature-dependent increases in firing frequency upon tissue damage.

251 ed, while glutamate cotransmission at phasic firing frequencies was reduced, enabling a selective foc

252 The median GPe firing frequency was higher in the NBIA group than in th

253 The median GPi firing frequency was higher in the primary group than in

254 During HF-SCS, mean peak SMU firing frequency was highest in the 3rd interspace (dors

255 anism underlying the TRH-induced increase in firing frequency was investigated using the perforated-p

256 n spike accommodation, whereas instantaneous firing frequency was unchanged.

257 ight similarly rise and fall in concert with firing frequency, we genetically engineered Drosophila t

258 xcitatory drive to the network, the neuronal firing frequencies were gradually and monotonically vari

259 vated potassium (SK) channels, regulators of firing frequency, were silenced in the CNS of Tg mice wi

260 lay low temporal summation and accelerate in firing frequency when depolarized, whereas COM neurons h

261 increased mean firing rate and instantaneous firing frequency, which could increase GnRH release, and

262 the modulation of Purkinje cell simple spike firing frequency, which has implications for controlling

263 ith short latency, followed by a decrease in firing frequency, which in turn was followed by an incre

264 hannels play a role in setting the intrinsic firing frequency, while BK channels regulate action pote

265 ermal nociceptors showed an increase in peak firing frequency with increased strength of mechanical s

266 ive afferents proportionally increased their firing frequency with stroking velocity and showed no te

267 ught to encode time of day by changing their firing frequency, with high rates during the day and low

268 revealed that both mutations increased cell firing frequency, with the R213Q mutation prompting more

269 mplitudes (the number of spikes in a burst), firing frequency within bursts or peak firing rate.