ライフサイエンスコーパス: firing pattern

1 tylcholine receptor antagonists impairs this firing pattern.

2 ed directions causes a grid cell's grid-like firing pattern.

3 ice preparation, V2a neurons exhibit a tonic firing pattern.

4 te the functional significance of the phasic firing pattern.

5 degrees orientations and has the most stable firing pattern.

6 duced and neurons exhibited a more irregular firing pattern.

7 e to the temporal nature of action potential firing patterns.

8 uspected heterogeneity and adaptivity in MEC firing patterns.

9 omputation of location that drives grid cell firing patterns.

10 replaced by low-entropy, stimulus-entrained firing patterns.

11 odulation of theta rhythmicity and grid cell firing patterns.

12 anglion cells in the two strains had similar firing patterns.

13 urons and in the temporal structure of their firing patterns.

14 uced changes in the preexisting goal-related firing patterns.

15 al ganglia movement disorders by normalizing firing patterns.

16 y, act primarily by eliminating pathological firing patterns.

17 lls could be distinguished based on neuronal firing patterns.

18 intensities, showed irregular or stuttering firing patterns.

19 differences in dendritic tree morphology and firing patterns.

20 l firing patterns but did not affect spatial firing patterns.

21 ar retrosplenial cortex showed bidirectional firing patterns.

22 and dendritic Ca(2+) spikes and in disrupted firing patterns.

23 er firing rates and more distributed spatial firing patterns.

24 um and potassium channels) to shape neuronal firing patterns.

25 how midbrain dopamine neurons modulate their firing patterns.

26 ion of the animal's position from population firing patterns.

27 rhinal cortex and to generation of grid cell firing patterns.

28 on the downstream parkinsonian basal ganglia firing patterns.

29 membrane activity, whereas GABA can modulate firing patterns.

30 urons (ORNs) respond to odorants with simple firing patterns.

31 l cells completely reorganized their spatial firing patterns.

32 dynamics beneath similar population average firing patterns.

33 tassium (Kv) channels that regulate temporal firing patterns.

34 proposed to account for place and grid-cell firing patterns.

35 d cells display strikingly symmetric spatial firing patterns.

36 by mossy fiber inputs with a wide variety of firing patterns.

37 rd a feed-forward mechanism that is coded by firing patterns.

38 rization of neuronal subtypes based on their firing patterns.

39 rons display considerable diversity in their firing patterns.

40 to regulate membrane excitability and spike firing patterns.

41 subregions led to different action potential firing patterns.

42 ing did not always necessitate modulation in firing patterns (2/12 cells in globus pallidus; 13/23 ce

43 rhinal cortex, which exhibit spatially tuned firing patterns [2, 3].

44 1) retrograde signaling initiated by in vivo firing pattern, (2) interneuron bAPs detected with fast

45 urons, exhibit tremendous diversity in their firing patterns, a consequence of the complex collection

46 is large, with minimal recurrence of spatial firing patterns across environments.

47 nge between behaviors in the coordination of firing patterns across neurons that could account for th

48 Grid cells exhibit hexagonal grid firing patterns across space in multiple spatial scales

49 majority of neurons ( approximately 90%) the firing patterns across the four tasks could be explained

50 We propose that the difference in firing pattern along the cochlea instructs the tonotopic

51 impact vs. incentive salience, and a faster firing pattern also distinguished incentive signals from

52 t cholinergically-induced changes in network firing patterns alter overall network synaptic potentiat

53 Moreover, 5-HT induced spatiotemporal firing pattern alterations could be monitored in neuron

54 spontaneously active, exhibiting a range of firing patterns, although only a minority (15%) exhibite

55 The firing pattern and the firing rate of layer 2/3 neurons

56 nteract in a highly nonlinear way to produce firing patterns and (2) across animals there is substant

57 um channels, but how they combine to control firing patterns and conduction is not well understood.

58 interpretation of corticospinal motor neuron firing patterns and help specify the logic of corticospi

59 rats, finding two classes of cells based on firing patterns and juxtacellular labeling (of a subset)

60 e extent to which it will determine neuronal firing patterns and network activity remains poorly unde

61 erations in axonal signaling affect neuronal firing patterns and neurotransmitter release, this is an

62 the basal ganglia, including both pathologic firing patterns and normal, task-related modulations in

63 of this hypothesis and discuss how specific firing patterns and oscillatory dynamics in the entorhin

64 for the temporal organization of hippocampal firing patterns and suggest that cognitive functions tha

65 y heterogeneous spontaneous action-potential firing patterns and their resting membrane potential is

66 ransmitter release, conduction velocity, and firing patterns and understanding the role of particular

67 They differ in their connectivity and firing patterns and, therefore, in their functional prop

68 nal populations defined as type I (irregular firing patterns) and type II (quiescent).

69 ls and influences action potential waveform, firing pattern, and rate.

70 intrinsically bursting action potential (AP) firing pattern, and the rest respond to injected depolar

71 ad that motor disorders derive from abnormal firing patterns, and have led to the hypothesis that sur

72 tanding which cell types correspond to which firing patterns, and how these correlates change with be

73 afterhyperpolarization, in the regulation of firing patterns, and in setting and stabilizing the rest

74 that include increased firing rate, altered firing patterns, and increased oscillatory activity.

75 trial variations in mean spike rate or burst-firing patterns, and potentially provides a principled f

76 ium currents, and tonic- or initial bursting firing patterns, and received weak excitatory synaptic i

77 ibitory currents are potent in modifying the firing patterns, and the inhibitory response to sound of

78 Overall, these studies reveal novel firing-pattern- and neural-circuit-specific mechanisms o

79 Temporally synchronized neural firing patterns are advantageous for efficiently represe

80 ransmitted to downstream neurons, persistent firing patterns are affected by prior experience in sele

81 rt a class of cells whose spatially periodic firing patterns are composed of plane waves (or bands) d

82 Behaviorally adequate neuronal firing patterns are critically dependent on the specific

83 Instead, we propose that place cell spatial firing patterns are determined by environmental sensory

84 Here we report that local firing patterns are distinctive: whereas multi-neuronal

85 Neuronal firing patterns are established by the collective activi

86 g of hippocampal neurons, but which specific firing patterns are induced by either of the two process

87 y govern survival of new neurons and precise firing patterns are not essential for neuronal integrati

88 In this view, grid and place cell firing patterns are not successive stages of a processin

89 nisms by which experience-related persistent firing patterns are regulated in specific neuronal popul

90 ational lesion," whereby pathologic neuronal firing patterns are replaced by low-entropy, stimulus-en

91 These models assume that grid-like firing patterns are the result of computation of locatio

92 n in neuroscience is to understand how noisy firing patterns are used to transmit information.

93 where we could definitively identify neural firing patterns as output-null or output-potent.

94 Here, we examined hippocampal neuronal firing patterns as rats ran in place on a treadmill, thu

95 tC neurons had preinspiratory or inspiratory firing patterns associated with excitatory effects on bu

96 C neurons had inspiratory or postinspiratory firing patterns associated with excitatory responses on

97 odulin activation specifically during neuron-firing patterns associated with induction of spike timin

98 erns are distinctive: whereas multi-neuronal firing patterns at larger distances can be predicted by

99 sion of motor neuron identity, virtually all firing patterns became distinctly flexor like.

100 ciations represented by hippocampal neuronal firing patterns but did not affect spatial firing patter

101 e not simply movement-related in their spike-firing patterns but instead were selectively modulated f

102 A depolarizing 'leak' current supports this firing pattern, but its molecular basis remains poorly u

103 that shapes action potentials and regulates firing patterns, but is not involved directly in trigger

104 tial location of an animal through localized firing patterns called "place fields." To explore the me

105 We show how such firing patterns can arise from quite small shifts in the

106 more show that other aspects of the observed firing patterns can be explained by learning that occurs

107 ently under natural conditions, and baseline firing patterns can impact neural coding (e.g., signal-t

108 After this disruption, new, stable spatial firing patterns can later form, but the new and original

109 Moreover, these firing patterns can repeat across similar subsegments of

110 However, the tonic firing pattern changed to burst firing exclusively durin

111 Significant firing pattern changes were observed more frequently in

112 iven boundary vector cell model leads to the firing patterns characteristic for boundary vector cells

113 developed into mature neurons and exhibited firing patterns characteristic of subpopulations of cort

114 Abnormal neuronal firing patterns characteristic of the fast deactivation

115 PMC neurons had homogeneous firing patterns, characterized by tonic activity and pha

116 kinematics over the ten-week period suggests firing patterns collected with the microchannel electrod

117 e-trial population spike trains into spatial firing patterns (combinations of neurons firing together

118 n to the ascending auditory nuclei, the IHCs firing pattern controlled by the alpha9alpha10 receptor

119 signal to hippocampus, and changes in their firing pattern could thus generate a distinct spatial co

120 Neurons with similar firing patterns could also have different effects on beh

121 a2+ entry in TC neurons during sleep-related firing patterns could be an important factor in maintain

122 ral tegmental area (VTA) where they regulate firing patterns critical for movement control, reward, a

123 is currently unknown whether these temporal firing patterns critically rely on upstream cortical inp

124 llidus; 13/23 cells in VLo), and regularized firing patterns did not always correspond to altered res

125 assayed, and the retinal ganglion cell (RGC) firing patterns, direction selectivity, vestibulomotor f

126 Spatial firing patterns distinguished the behaviorally identical

127 GABAA conductance transforms the interneuron firing pattern driven by individual EPSPs into a more re

128 atory neurons generate a unique and reliable firing pattern during sensory stimulation and that this

129 Acoustic responses and neuronal firing patterns during AGS were compared in non-kindled

130 esence of an aversive stimulus, modify their firing patterns during emotional learning, and stabilize

131 he level of single neurons induced by normal firing patterns during free behavior.

132 g the 'reactivation' of the original network firing patterns during sleep and rest.

133 nce of the LFP, the organization of neuronal firing patterns during spindles bears little resemblance

134 coordinated replay of prior learning-related firing patterns during subsequent NREM sleep.

135 istical summaries properly characterized the firing patterns (e. g. template and variability) and qua

136 between Et and controls were observed in the firing pattern elicited in layer 5 neurons by steps of d

137 able and long-lasting sequences of transient firing patterns, even in the absence of changing externa

138 lts in a significant disruption of grid cell firing patterns, even when the quality of the directiona

139 on information influences spatially-specific firing patterns exhibited by hippocampal neurons.

140 ng spike patterns, and retrieved informative firing patterns expressed by the same population in resp

141 owever, with prolonged experience, grid cell firing patterns formed a single, continuous representati

142 supporting a diversity of multineuron spike firing patterns from overlapping sets of neurons.

143 selective modulation of SPNs based on their firing patterns; FSIs inhibit most SPNs but paradoxicall

144 hannelrhodopsin-2, enable precise control of firing patterns; green fluorescent protein-based reporte

145 allidus, (2) a monophasic stimulus-entrained firing pattern in motor thalamus, and (3) a complete or

146 mediate spontaneous activity and changes of firing pattern in these neurons is essential for underst

147 ation, hippocampal neurons show a sequential firing pattern in which individual neurons fire specific

148 teracts with the switching between different firing patterns in a state-dependent and type-dependent

149 The changes in firing patterns in basal ganglia neurons were not correl

150 However, burst firing patterns in both nuclei in the slow-wave activity

151 To elucidate the origin of firing patterns in branched mechanoreceptors, we combine

152 associative learning, that the coherence of firing patterns in directly connected entorhinal-hippoca

153 ntially affected, such that action potential firing patterns in dorsal mEC-SCs were altered, while th

154 ) GP-DBS resulted in: (1) stimulus-entrained firing patterns in globus pallidus, (2) a monophasic sti

155 de and that maintain their vocalization-like firing patterns in levels of background sound that permi

156 computational study proposed that population-firing patterns in parietal cortex have one-dimensional

157 action regulates the emergence of persistent firing patterns in specific neuronal populations.

158 Here we compare conductance and firing patterns in spinal motoneurons during network act

159 ronal excitability, transmitter release, and firing patterns in thalamic networks, thereby altering t

160 stems from increasing the regularity of the firing patterns in the basal ganglia (BG).

161 We found that grid-like firing patterns in the entorhinal cortex vanished when t

162 on a microscopic scale, in relation to their firing patterns in the environment would facilitate a gr

163 tcome-predicting cues induced a remapping of firing patterns in the HC, consistent with its role in e

164 d with increased synchronization of neuronal firing patterns in the hippocampus and the connected ven

165 ctopic discharges included burst and regular firing patterns in the IAN and V2 branches of the TG neu

166 espondingly, we studied the evolution of the firing patterns in the loop.

167 approach responses are represented in neural firing patterns in the major output structure of the mes

168 tivity but could also contribute to abnormal firing patterns in the parkinsonian STN.

169 In the recordings, we found distinct firing patterns in the striatum, globus pallidus, and su

170 : The capability to disentangle superimposed firing patterns in upstream networks, and to represent t

171 regulation of their AP shape during natural firing patterns in vivo.

172 sive stimuli exposure produced heterogeneous firing patterns in VTA-projecting BNST neurons.

173 rates but for driving task-specific cortical firing patterns, including bursts.

174 and how this functional coupling affects the firing patterns induced by sustained current injections.

175 Understanding this shared variability in firing patterns is critical for appreciating the represe

176 lts suggest that the observed differences in firing patterns likely reflect dissimilarities in task a

177 These differences in firing patterns may be due to variations in behavioral c

178 Identification of specific firing patterns may help determine targets and patient-s

179 Task-dependent alterations in place cell firing patterns may reflect the operation of the hippoca

180 The in vivo firing pattern modulated the size of unitary EPSPs impin

181 ferior colliculus (IC), the diverse temporal firing patterns must be coded by other synaptic mechanis

182 This is at odds with firing patterns observed in the cortex of intact animals

183 In females, estradiol shifts the firing pattern of AVPV/PeN Kiss1 neurons and alters cell

184 nd how tonic GABAA conductance regulates the firing pattern of CA3 interneurons.

185 Furthermore, this plasticity altered the firing pattern of CINs increasing the variance of action

186 The tonic firing pattern of dopamine cells responds to these input

187 out the ion channel machinery that specifies firing pattern of enteric neurons.

188 The spatial firing pattern of entorhinal grid cells may be important

189 of retinal waves, they strongly modulate the firing pattern of individual RGCs, ensuring strongly cor

190 Our experiments revealed that the firing pattern of many hypothalamic cells was influenced

191 The firing pattern of midbrain dopamine (DA) neurons is well

192 Moreover, although a distinct firing pattern of Mthal neurons, called low-threshold ca

193 (ChR2) in brain tissue, and consequently the firing pattern of neurons, by manipulating the phase of

194 tions and the rapid formation of the spatial firing pattern of place cells.

195 Purkinje neurons have a complex firing pattern of regular spikes interrupted by intermit

196 alleviated age-dependent dysfunction in the firing pattern of SCA2 PCs.

197 tractor corresponding to a different spatial firing pattern of sparks.

198 the mechanism considered here (the change in firing pattern of subthalamic neurons through the dopami

199 These "attract" the firing pattern of the network to a stored pattern, even

200 nd inhibitory synaptic currents to shape the firing pattern of the neuron.

201 aptic plasticity that regulates the temporal firing pattern of the principal output cells of the cere

202 inesia is causatively regulated by the burst-firing pattern of the subthalamic nucleus (STN) in a fee

203 The observed firing patterns of CA3 meet these criteria and can be qu

204 ostsynaptic cholinergic receptors encode the firing patterns of CHIs in the striatum.

205 tures of sensory scenes to be encoded in the firing patterns of cortical populations.

206 Our results show that firing patterns of densely perturbed oscillators cannot

207 we have characterized ionic conductances and firing patterns of developing zebrafish spinal neurons.

208 y roles in network oscillations, the in vivo firing patterns of distinct hippocampal interneurons in

209 light stimulation method for modulating the firing patterns of electrically-excitable cells using su

210 rocedures demonstrated no differences in the firing patterns of GPi neurons from DYT1 and DYT6 patien

211 rdcastle et al. (2015) show that the spatial firing patterns of grid cells accumulate error, drifting

212 The firing patterns of grid cells in medial entorhinal corte

213 The periodic spatial firing patterns of grid cells in the hippocampal formati

214 hat environmental novelty causes the spatial firing patterns of grid cells to expand in scale and red

215 sory input in generating the regular spatial firing patterns of grid cells, and changes in grid cell

216 Compared with CA1, the firing patterns of hippocampal CA3 cell populations are

217 hat both the discharge rates and the spatial firing patterns of individual cells will be distinct in

218 We show that standard spatial and temporal firing patterns of individual hippocampal principal neur

219 atory activity interacting strongly with the firing patterns of inhibitory neurons, suggesting a proc

220 The firing patterns of interneurons developed a relationship

221 ng algorithms have been used to identify the firing patterns of isolated neurons ('single units') fro

222 ell-type identification, to characterize the firing patterns of monosynaptic inputs to dopamine neuro

223 es high-frequency action potentials, but the firing patterns of most peptide/GABA-releasing interneur

224 ntributions to schema updating by monitoring firing patterns of multiple CA1 neurons as rats learned

225 The firing patterns of neurons contained enough information

226 The firing patterns of neurons in the globus pallidus (GP) a

227 This work indicates that the spatial firing patterns of neurons in the medial entorhinal cort

228 erneurons play critical roles in shaping the firing patterns of principal neurons in many brain syste

229 Although the firing patterns of principal neurons in the olfactory bu

230 that Rac1 modulates SK channel activity and firing patterns of Purkinje cells.

231 consortium of inhibitory neurons control the firing patterns of pyramidal cells, but their specific r

232 other parts of the brain, so we examined the firing patterns of rat subicular neurons.

233 We used phase resetting methods to predict firing patterns of rat subthalamic nucleus (STN) neurons

234 mulating and inhibiting the action potential firing patterns of SH-SY5Y human neuroblastoma cells and

235 cal and chemical stimulation showed specific firing patterns of spike frequency adaptation, postinhib

236 iginates in the circuitry that regulates the firing patterns of spinal motorneurons.

237 We show how the changes in firing patterns of STN neuron due to the lack of dopamin

238 By altering firing patterns of STN neurons, this NMDA/K-ATP interact

239 n the oligodendrocyte lineage to monitor the firing patterns of surrounding neurons.

240 o maximize information transfer for specific firing patterns of the corresponding neurons.

241 e spike threshold, filtering properties, and firing patterns of the different motoneuron pools are gr

242 Finally, the distinct firing patterns of the electrically coupled neurons were

243 Percepts in our model are identified in the firing patterns of the neuronal units.

244 When comparing the firing patterns of the same neurons across brain states

245 potentials that are critical to shaping the firing patterns of these cells.

246 combined with self-motion information in the firing patterns of these cells.

247 However, this system is complex because firing patterns of these neurons are heterogeneous; subp

248 most cases, the distribution and dynamics of firing patterns of these neurons during behavior are not

249 tactile information, the highly reproducible firing patterns of these neurons suggest that a single s

250 In contrast, the heterogeneous firing patterns of VPvm neurons may implicate VPvm in fa

251 e model that predicts the dependence of IHCs firing patterns on the level of activation of two parame

252 d how circuit structure gives rise to neural firing patterns or computations is fundamental to our un

253 h switch, but did not develop anticorrelated firing patterns or predict choice accuracy.

254 ce, based solely on the neurons' fluctuating firing patterns, or it may occur too frequently to be ex

255 does not interfere with the action potential firing pattern, pharmacological ablation of the alpha9al

256 s are necessary for generating grid-specific firing patterns, possibly by driving velocity modulation

257 We found that the "in vivo firing pattern" produced a transient firing-induced supp

258 To investigate whether spatial firing patterns recur when animals are exposed to multip

259 cified neurons had synaptic properties and a firing pattern reminiscent of a pyramidal cell-like phen

260 l, on the replay of spatially tuned neuronal firing patterns representing discrete places and spatial

261 provide inputs to the hippocampus, and their firing patterns shift relative to each other across diff

262 channels increases the variability in their firing pattern, sometimes also increasing the number of

263 neurons encode both modalities with similar firing patterns (stimulus-synchronized or nonsynchronize

264 ations of neurons firing together), temporal firing patterns (temporal activation of these groups of

265 perirhinal cortex of rats generate sustained firing patterns that discriminate large segments of the

266 al cortex exhibit remarkably regular spatial firing patterns that tessellate all environments visited

267 However, accumulating phase noise causes the firing pattern to drift and become corrupted.

268 ls in the hippocampus retained their spatial firing patterns to a larger extent during these periods

269 Using these firing patterns to generate realistic inputs to our netw

270 s repetitive firing, and can convert regular firing patterns to irregular ones.

271 otoneurons and compared their current-evoked firing patterns to network-driven ones in the larval zeb

272 rate and universal metric requires grid cell firing patterns to uniformly cover the space to be navig

273 Although there was no firing pattern unique to either core or shell, the rewar

274 ers of Na(+) and K(+) channels, are similar, firing patterns vary among cell types.

275 uced a shorter NIP, and this altered network firing pattern was normalized by clonazepam, a positive

276 pyramidal cells (clustered vs uniform), and firing patterns (weakly vs highly synchronized).

277 Neuronal firing patterns were analysed by constructing hazard fun

278 es to the multicompartment environment, grid firing patterns were dominated by local environmental cu

279 In contrast, VPvm firing patterns were heterogeneous, changing FRs during

280 this finding, both regular-spiking and burst firing patterns were profoundly depressed in the mouse w

281 during these response periods, a variety of firing patterns were seen that could be broadly describe

282 However, grid cell firing patterns were unaffected, concordant with an abse

283 atial cells and confirmed that their spatial firing patterns were unrelated to running speed and high

284 s and are necessary for characteristic burst firing patterns which serve to maximize hormone release.

285 The calyx showed a characteristic burst firing pattern, which has previously been shown to origi

286 term alterations in medial rectus motoneuron firing pattern, which were more drastic in MLF of animal

287 reorganization of the postsaccadic neuronal firing patterns, which follow a similar retinotopic prog

288 ze of the AIS likely underlie differences in firing pattern, while the tapering diameter of AIS may d

289 bit both phasic and regular-spiking tonic AP firing patterns, while dlPFC neurons exhibit only tonic

290 Typical NGFCs exhibited a late firing pattern with a ramp in membrane potential prior t

291 (FS) interneurons predominately had a tonic firing pattern with very few exhibiting bursting activit

292 exhibit considerable heterogeneity in their firing patterns with both similarities and differences t

293 unique in our sample in expressing circadian firing patterns with highest activity during the mid pro

294 one would like to combine precise control of firing patterns with highly sensitive probes of cellular

295 of a radial maze, and (3) discharged similar firing patterns with respect to the goals, both on multi

296 3 neurons discharged in spatially irregular firing patterns, with weak theta-modulation and head-dir

297 nimals would reveal dynamic shifts in neural firing patterns within and across sensory, sensorimotor,

298 have been linked to abnormal and hyperactive firing patterns within the auditory system, these result

299 rates of transgenic neurons are reduced, and firing patterns within Up states are altered, with longe

300 This shift in stimulus-evoked firing pattern would allow downstream structures to dist