ライフサイエンスコーパス: firing rate

1 ics and/or performance errors independent of firing rate.

2 ncidentally, above and beyond their baseline firing rate.

3 correlation level into a mean change in the firing rate.

4 uniform in size, number of spikes, and peak firing rate.

5 , which also exhibited increased spontaneous firing rate.

6 neurons, and reduced leak Na(+) current and firing rate.

7 t can act directly on MNCs to modulate their firing rate.

8 g rate to its own expected future discounted firing rate.

9 eficits, including decreased gamma power and firing rate.

10 Q-preferring, or nonselective based on total firing rate.

11 s and the spiking correlation increases with firing rate.

12 he autocorrelogram, waveform parameters, and firing rate.

13 nt will eventually also elevate the neuron's firing rate.

14 deficits including decreased gamma power and firing rate.

15 hisking kinematics through linear changes in firing rate.

16 potential with a resultant reduction in the firing rate.

17 nt and underlie the steep initial rise in MU firing rate.

18 neuron firing that did not alter the overall firing rate.

19 ientation or direction by suppression of the firing rate.

20 e for the initial sharp rise in motor neuron firing rate.

21 with a subsequent reduction in simple spike firing rate.

22 d changing repetition frequency by increased firing rate.

23 orrelations can increase systematically with firing rate.

24 ease, and, consequently, reduced spontaneous firing rate.

25 athway might curb this initial steep rise in firing rate.

26 o hypoxia by either increasing or decreasing firing rate.

27 cells only included state cells with reduced firing rates.

28 quencies, and as a result efficiently encode firing rates.

29 ata are often unstable, leading to divergent firing rates.

30 tes was wide and strongly skewed toward high firing rates.

31 d an approximately lognormal distribution of firing rates.

32 tatic effects on both synaptic strengths and firing rates.

33 , but not in the probability distribution of firing rates.

34 sticity, sparse coding, and modifications of firing rates.

35 significant ITD sensitivity in their overall firing rates.

36 ation about coarse natural image features as firing rates.

37 olarizing these neurons and increasing their firing rates.

38 aterals and reduction in background striatal firing rates.

39 tation within CA1, thus leading to unaltered firing rates.

40 he negative feedback mechanism that controls firing rates.

41 l visuomotor continuum based on task-related firing rates.

42 ip emerged between pairwise correlations and firing rates.

43 showed reduced spontaneous and sound-evoked firing rates.

44 onal spiking activity across a wide range of firing rates (10 Hz to 150 Hz).

45 at one end of the continuum increased their firing rates 150 ms after stimulus onset and these firi

46 V1 neurons preferring low SF (mean change in firing rate: -8.0%), whereas silencing PM L5 feedback su

47 essing deficits manifested as an increase in firing rate, a broadening of the frequency response area

48 explain why covariation of correlations with firing rate-a relationship previously explained in feedf

49 ng" activity, a monotonic change in neuronal firing rate across time, is observed throughout frontost

50 By contrast, the effect of REM was to reduce firing rates across the entire rate spectrum.

51 We find a rich diversity of firing rates across the neuronal population as reflected

52 e probability distribution of sensory neuron firing rates across the population of odorant sensory ne

53 d predominantly responded with redistributed firing rates across their grid fields.

54 an give rise to a novel state in which local firing rates adjust dynamically so that adaptation curre

55 the other end of the continuum reduced their firing rate after stimulus onset, while "perimovement" n

56 able accurate transmission of gain-modulated firing rates, allowing neuronal firing to be efficiently

57 ilarity via either increases or decreases in firing rate, although only shell neurons showed a signif

58 s associated with a substantial reduction in firing rates among a large subpopulation of cortical neu

59 ormation coded in mean population current or firing rate amplitudes.

60 hat a single cocaine injection increases the firing rate and bursting activity of VTA dopamine neuron

61 yers exhibit attention-mediated increases in firing rate and decreases in variability.

62 approaches, we identified decreased neuronal firing rate and deficits in gamma frequency in the prefr

63 oextracellular recordings, we show decreased firing rate and gamma frequency power in the prefrontal

64 tion neurons displayed an increased baseline firing rate and loss of sensitivity to acute ethanol fol

65 Here, we show that the mean firing rate and neuronal gain increase during locomotion

66 eceptors on LC neurons, resulting in reduced firing rate and norepinephrine release.

67 We show that the firing rate and spatial selectivity changed with cue rel

68 c complex tones and exhibited an increase in firing rate and temporal pattern changes when one freque

69 free choice protocol for 8 weeks), the basal firing rate and the excitability of LHb neurons in brain

70 al cortex, with changes evident in grid cell firing rate and the local field potential theta frequenc

71 f inhibitory neurons, both in terms of their firing rate and their phasic firing with the oscillation

72 central node can be tuned to have a certain firing rate and variability, or to allow for an optimal

73 ducing the expansive nonlinearity that links firing rate and variance.

74 on of iSPNs, which often displayed excessive firing rates and aberrant phase-locked firing to cortica

75 ced heightened anxiety, decreased BLA neuron firing rates and attenuated the CS-induced increase in B

76 ration of phospho-CREB in the face of higher firing rates and bigger Ca(2+) transients.

77 for joint alterations in the observed neural firing rates and correlations; (2) Neural circuit functi

78 their neurites, and increasing POMC neuronal firing rates and excitability.

79 creasing the tone and noise levels increased firing rates and expanded bandwidths, as is usually seen

80 dopamine neurons might be important for low firing rates and fine-tuning basal dopamine levels, whil

81 Alcohol increases CeA activity (neuronal firing rates and GABA release) in naive rats by engaging

82 led to a reduction of attentional effects on firing rates and gamma synchrony in V4, a reduction of s

83 bility in basic neuronal properties, such as firing rates and inter-spike interval distributions.

84 MU population model was used to simulate MU firing rates and isometric muscle forces and, to that mo

85 ts, those in older participants had 8% lower firing rates and larger MUP size (+25%), as well as incr

86 d the effects of adaptation on single-neuron firing rates and local field potentials; this mechanisti

87 increasing the tone and noise levels reduced firing rates and narrowed FRA bandwidths; at higher SNRs

88 Pallidal firing rates and patterns differ significantly with dyst

89 ntion increases coding abilities by altering firing rates and rate variability.

90 he stimulus in the form of slowly increasing firing rates and reach a decision when those firing rate

91 are by looking at the distribution of field firing rates and reproducibility of this distribution ac

92 The high convergence, firing rates and strength of Purkinje inputs predict pow

93 variability because attention both increases firing rates and their stimulus sensitivity, as well as

94 his elevated excitation results in increased firing rates, and abnormal coding of frequency and binau

95 where the major effect is the increasing of firing rates, and in layer V, where the major effect is

96 We found that small changes in firing rate ( approximately 1 Hz) occurred across a broa

97 ndings indicate that wake-related changes in firing rates are determined not only by wake duration, b

98 Specifically, cortical firing rates are significantly higher towards the end of

99 d features as predictors and spike counts or firing rates as responses.

100 cluding destabilized grid fields and reduced firing rates, as well as altered network activity.

101 ural responses, producing complex changes in firing rates, as well as modifying the structure and siz

102 d changes in MU force, contraction time, and firing rate associated with sustained voluntary contract

103 windowing at lower pulse rates, and overall firing rate at higher pulse rates, neural ITD JNDs were

104 e feedback, perhaps driving increased neural firing rate at this time.

105 decreased firing at 200-300 pA and increased firing rates at 450 pA), whereas insignificant morpholog

106 bit two-dimensional tuning curves, with peak firing rates at a preferred vertical orientation.

107 al representations of time-varying sounds to firing rate-based representations.

108 ) and "indirect pathway" SPNs (iSPNs); their firing rates became imbalanced, and they disparately eng

109 lity was improved, even for fixed population firing rates, because of a decrease in noise correlation

110 ot only changes their membrane potential and firing rate but as a secondary action reduces membrane r

111 pikelets are preceded by higher simple spike firing rates but, following the complex spike, simple sp

112 ery of rudimentary sound features encoded by firing rate, but not features encoded by precise spike t

113 esent whisker movement via linear changes in firing rate, but the circuit mechanisms underlying this

114 manipulation of inhibitory strength altered firing rates, but did not change the strength of surroun

115 rkinje-mediated IPSCs, and lower spontaneous firing rates, but rotarod performances were indistinguis

116 us-dependent correlations that increase with firing rate can have beneficial effects on information c

117 ls or light-off cells according to how their firing rate changed in acute response to light, or as no

118 abling top-down attention, attention induced firing rate changes are profound, but its effect on diff

119 lar layer interneurons exhibit bidirectional firing rate changes during whisking, similar to PCs.

120 al attention in human and nonhuman primates, firing rate changes with attention occur, but rate varia

121 layer interneurons results in unidirectional firing rate changes, increased SSp regularity and disrup

122 remaining afferent inputs, thereby restoring firing rate codes for rudimentary sound features.

123 rneurons recorded from old animals had lower firing rates compared with those from young animals.

124 Specific forms of firing rate correlations can limit efficient information

125 rates 150 ms after stimulus onset and these firing rates covaried systematically with choice, stimul

126 tter increased, while spontaneous and evoked firing rates decreased, suggesting that deprivation caus

127 quantified the extent to which variation in firing rates depended on location, on object, and on the

128 dystonia and investigate whether GPi and GPe firing rates differ between dystonia types.

129 he net result of sleep was to homogenize the firing rate distribution.

130 While firing rates do not change within the targeted area, tDC

131 sk, we report that OT neurons modulate their firing rate during initiation and progression of the ins

132 context cue, by increasing or decreasing the firing rate during the stationary periods following cloc

133 FEF neurons increase their firing rate during the three epochs of the memory-guided

134 They have stable firing rates during prolonged periods of stimulation and

135 F"/"ON" time ratios but did not alter Pol II firing rates during the "ON" period.

136 mean response properties of population-scale firing rate dynamics.

137 First, locomotion-induced increases in firing rates enhanced the mutual information between vis

138 theless, the corresponding Wilson-Cowan type firing rate equation for such an inhibitory population d

139 ng neurons which is not captured by standard firing rate equations.

140 of the conversation, with greater changes in firing rate evident for longer conversations.

141 owever, we also find that PN and interneuron firing rates exhibit significant 10-Hz rhythmicity locke

142 Additionally, firing rates exhibited a linear decrease in sequences of

143 ion times were strongly related to modulated firing rates (F1 values) generated by drifting grating s

144 The impact of firing rate fluctuations on network and perceptual accur

145 y (measured in terms of coordination between firing rate fluctuations) was globally stronger in wakef

146 This subpopulation of neurons showed blunted firing rates following rewards in alcohol-consuming rats

147 Cortical firing rates frequently display elaborate and heterogene

148 iched with cells with small RFs, high evoked firing rates (FRs), and sustained temporal responses, wh

149 Here, we monitored firing rate homeostasis in individual visual cortical ne

150 Sh, mPFC, and LH, in a manner that maintains firing rate homeostasis.

151 ically-quiescent, muscles, the instantaneous firing rates (IFRs) of muscle spindles are associated wi

152 than-expected reward resulted in a decreased firing rate in 20-35% of the neurons.

153 pected reward caused a transient increase in firing rate in 60-80% of the total neuronal sample, wher

154 They observed gains in firing rate in auditory cortex despite nearly absent aud

155 (LOST) model to decompose the instantaneous firing rate in biologically and behaviorally relevant fa

156 Half of the MEC neurons changed their firing rate in darkness.

157 (XE991)-induced increase in the spontaneous firing rate in LHb neurons was smaller.

158 t may underlie the initial steep increase in firing rate in motor neurons.

159 is the major causal determinant of the tonic firing rate in the intact model, by virtue of the higher

160 tion potentials, is a key determinant of the firing rate in these neurons.

161 The average population firing rate in these states is typically low.

162 increase in the single-unit action potential firing rate in vivo in VTA dopamine neurons, which was b

163 and laminar organization of decision-related firing rates in dorsal premotor cortex.

164 ced CTA caused significantly higher baseline firing rates in LHb neurons, as well as elevated firing

165 They discuss alternate analyses of average firing rates in other tasks, the relationship between ne

166 her open probabilities, leading to increased firing rates in rat hippocampal neurons.

167 lationship between pairwise correlations and firing rates in recurrently coupled excitatory-inhibitor

168 We found that DMV neurons maintain normal firing rates in response to ASOX.

169 ng rates in LHb neurons, as well as elevated firing rates in response to cue presentation, lever pres

170 motoneurons, axonal L-type channels enhance firing rates in unmyelinated Drosophila motoraxons.

171 , showed weaker impulse responses and a slow firing rate increase during sequences.

172 aded isometric contractions, motor unit (MU) firing rates increase steeply upon recruitment but then

173 aded isometric contractions, motor unit (MU) firing rates increase steeply upon recruitment but then

174 neurons undergo one-time, discrete steps in firing rate instead of gradual changes that represent th

175 LOST is able to detect oscillations when the firing rate is low, the modulation is weak, and when the

176 r space, we discovered that each face cell's firing rate is proportional to the projection of an inco

177 red variability, increased correlations with firing rates, limited range correlations, and differenti

178 nset latencies nor noise-driven steady-state firing rates meaningfully interacted with SNRs or overal

179 Here we utilize a firing rate model and a computational model to elucidate

180 ness under all tested conditions whereas the firing rate model does not.

181 e then implemented the spatial variation and firing rate models of roughness based on these simulated

182 otentials that drive neuronal plasticity and firing rate modulation.

183 in alone, but behavior or stimulus triggered firing-rate modulation, spiking sparseness, presence of

184 This produces firing rate modulations and receptive field shifts.

185 ny was higher, excitation increased CbN cell firing rates more effectively.

186 lity across cortical layers, with changes in firing rates most important in the upper layers and chan

187 Tutor similarity predicted firing rates most strongly during early stages of learni

188 The result was consistent across varying firing rates, network sizes, and topologies.

189 rrelations for different correlation levels, firing rates, network sizes, network densities, and topo

190 of nonREM sleep reduced the activity of high firing rate neurons and tended to upregulate firing of s

191 ded while the inhibitory reflex was engaged, firing rates no longer increased steeply, suggesting tha

192 actors: spiking refractoriness, event-locked firing rate non-stationarity, and trial-to-trial variabi

193 addition to the sample length, bin size, and firing rate, number of active hippocampal pyramidal neur

194 .SIGNIFICANCE STATEMENT We report that lower firing rates observed in aged perirhinal cortical princi

195 tedly followed by an event that elevates the firing rate of a neuron, the originally neutral event wi

196 hermore, astrocytic activation decreased the firing rate of CeM neurons and reduced fear expression i

197 on of ethanol dose-dependently decreased the firing rate of low-frequency GPe neurons, but did not al

198 In contrast, both manipulations altered the firing rate of MEC neurons without changing their firing

199 onmetric contextual cues, also regulates the firing rate of MEC neurons.

200 leotide-gated cation channels decreasing the firing rate of MNCs and the consequent secretion of VP a

201 , orientation filtering did not modulate the firing rate of neurons to phase-scrambled face stimuli i

202 elected at different time points, changes in firing rate of nigrostriatal dopamine neurons, as well a

203 GCs were rendered silent while enhancing the firing rate of OFF RGCs, c-Fos expression was greatly in

204 tor projection eliminated the characteristic firing rate of premotor neurons.

205 umin-positive interneurons and decreases the firing rate of pyramidal neurons, phenomena mimicked by

206 +) influx in IHCs, and increased the maximal firing rate of SGNs at sound onset.

207 Similar to the firing rate of single neurons, correlated activity can b

208 The firing rate of single OFC neurons distinguished identica

209 ion of serotonin significantly increased the firing rate of spontaneous action potentials, demonstrat

210 frontality" in dmPFC and OFC by reducing the firing rate of spontaneously active neuronal subpopulati

211 l pathway while keeping constant the average firing rate of substantia nigra pars reticulata reduces

212 stimuli can either increase or decrease the firing rate of the cell, depending on contrast.

213 inverse membrane time constant and the mean firing rate of the neuron.

214 The time-averaged firing rate of the SCN is modestly increased under these

215 e in CO2/H+ typically reflects a rise in the firing rate of these neurons, which stimulates an increa

216 icantly inhibited the spontaneous and evoked firing rate of third order thalamocortical projection ne

217 rved in adult MAM animals, as well as higher firing rates of BLA neurons in both peripubertal and adu

218 n caused significant changes in the relative firing rates of individual grid fields, reconfiguring th

219 The firing rates of many lateral SNR neurons were time-locke

220 ally activated during voluntary contraction, firing rates of motor neurons increase steeply but then

221 the effect of microstimulation in V1 on the firing rates of MT neurons.

222 s of neural activity in that it assumes that firing rates of neurons are sensitive to multiple discre

223 for by differences in running speed, as the firing rates of PER interneurons did not show significan

224 Here, we show a similar effect in the firing rates of primary motor cortical cells.

225 Simulated depolarization increased baseline firing rates of pyramidal neurons, which altered their s

226 interspersed within nonREM epochs, increased firing rates of slow-firing neurons.

227 Firing rates of some neurons were phasically selective f

228 ine depletion stem from the disproportionate firing rates of spiny projection neurons (SPNs) therein.

229 mRNA counts, Pol II density and Pol II firing rates of the Ccnb1 promoter transgene resembled t

230 Rate remapping readjusts the firing rates of this set depending on current experience

231 spikelets/CS correlated with the average SS firing rate only for Z+ cells.

232 disease symptoms on the basis of changes in firing rate or firing synchronization/rhythmicity.

233 ace fields in CA2 with no effect on neuronal firing rate or immediate early gene expression.

234 SPW-R silencing did not impact the firing rates or proportions of place cells.

235 errors and are not due to differences in SS firing rates or variability.

236 alysis over a wide range of AP waveforms and firing rates, owing in part to the use of an iterative a

237 r response fluctuations and choices, and had firing rate patterns consistent with their sensory role

238 Neurons in area LIP exhibited firing rate patterns that directly resembled the evidenc

239 wo interneuron populations differed in their firing rates, patterns and relationships with cortical o

240 MUP size, firing rates, phases, turns and near fibre (NF) jiggle w

241 Here we show that firing rate potentiation, a form of intrinsic plasticity

242 s in postsynaptic excitability, occlusion of firing rate potentiation, and reductions in BK currents

243 t the correlation of spikelet number with SS firing rate primarily reflected a relationship with non-

244 Firing rate profiles (expressed as a function of contrac

245 the idea that PICs contribute to non-linear firing rate profiles during ascending but not descending

246 Firing rate profiles for the descending phases of the co

247 e of the triangular contractions, 93% of the firing rate profiles were best fitted by rising exponent

248 With stimulation, however, firing rate profiles were best fitted with linear functi

249 ed a remarkable form of temporal invariance: firing rate profiles were temporally scaled to match the

250 e strength of SA1 responses - the population firing rate - rather than their spatial layout.

251 firing rates and reach a decision when those firing rates reach a threshold.

252 ith lengthening of the wake period enhancing firing rate rebound.

253 ire neurons in the inhibition-dominated, low firing rate regime.

254 isms do, or do not, produce this correlation-firing rate relationship.

255 response variability were to decrease while firing rate remained constant, then neural sensitivity c

256 By contrast, maximum intraburst firing rates require axonal calcium influx through Dmca1

257 n the high gamma band, which correlates with firing rate response.

258 The firing-rate response increased indefinitely with injecte

259 A sensitivity analysis for the firing-rate response to the different stimuli revealed t

260 nucleus (LGN) neurons, leading to increased firing-rate responses to the presented stimulus orientat

261 nchrony and bursting, as well as spontaneous firing rate (SFR), correlated with behavioral evidence o

262 otential (AP) generation, measured as higher firing rate, shorter EPSP-AP delay in vivo and shorter A

263 relationship between neuronal morphology and firing rate showed that dopaminergic neurons function as

264 of MS input resulted in strengthening of the firing rate speed signal, while decreasing the strength

265 nge in the slopes of the theta frequency and firing rate speed signals thought to be used by grid cel

266 fibers (ANFs) exhibit a range of spontaneous firing rates (SRs) that are inversely correlated with th

267 er of 10-30 ANFs with a range of spontaneous firing rates (SRs).

268 Using optogenetics we show that at increased firing rates tectal-derived dLGN-INs generate a powerful

269 ten use either an oscillatory frequency or a firing rate that increases as a function of running spee

270 ion/direction-selective (OS/DS) cells with a firing rate that is suppressed by drifting sinusoidal gr

271 tifying a population-wide increase in neural firing rates that corresponded with the hand being near

272 Furthermore, when correlations covary with firing rate, this relationship is reflected in low-rank

273 try in the antennal lobe constrains the mean firing rate to be the same for all odors and concentrati

274 two-compartment neuron to match its current firing rate to its own expected future discounted firing

275 ited persistent and tuned suppression of the firing rate to subsequent SAM signals.

276 y midbrain, for example, rapidly adapt their firing rates to enhance coding precision of common sound

277 Face-responsive neurons showed reduced firing rates to expected faces, an effect consistent wit

278 ural population responses and predict neural firing rates to faces.

279 Here, we show that in vivo, both the firing rate (tonic activity) and burst firing (phasic ac

280 It was found that THC left firing rate unaltered and only slightly reduced theta os

281 -chain' domain rescues BK current levels and firing rate, unexpectedly contributing to the subthresho

282 RH excitability, a key determinant of neural firing rate using laboratory and computational approache

283 ming can be equivalently induced by a modest firing rate variation.

284 The recovery of the mean firing rate was close to pre-ictal levels also within th

285 tly, this social context-dependent change in firing rate was evident even before subjects heard the v

286 n the deafened condition was steeper and the firing rate was higher than in the hearing condition at

287 Although the firing rate was not altered, the regularity of DA cell f

288 rved that the distribution of pyramidal cell firing rates was wide and strongly skewed toward high fi

289 When neuronal firing rates were perturbed by visual deprivation, they

290 Many state cells with increased firing rates were S cells, whereas R cells only included

291 DAP firing rates were several-fold larger than somatic rates

292 Finally, we found that spontaneous firing rates were shifted up or down by dnCaMKIV or caCa

293 Finally, firing rates were significantly higher during consumptio

294 s a critical role in setting the basal tonic firing rate, which in turn could control striatal dopami

295 vo We observed a positive correlation of the firing rate with both proximity and size of the AIS.

296 -monotonic neurons (monotonically increasing firing rate with increasing stimulus repetition frequenc

297 kade of HCN channels by ZD7288 decreases MNC firing rate with significant consequences on the release

298 stabilize neural circuit function by keeping firing rates within a set-point range, but whether this

299 able sequence of states (each defined by the firing rates within the ensemble) separated by brief sta

300 olarization, which increases the spontaneous firing rate without affecting the resting membrane poten