ライフサイエンスコーパス: first step

1 er from TsOH (tau approximately 3 ns for the first step).

2 a novel approach that clusters k-mers as the first step.

3 e mixed disulfide intermediate formed in the first step.

4 oose between the two rewards selected in the first step.

5 equires appropriate risk stratification as a first step.

6 ative trait loci based on estimates from the first step.

7 ing a two-step approach, which included as a first step, a biological selection of genes, which are i

8 In the first step, a multicomponent alkynyl halo-Prins reaction

9 In the first step, a one-class model was developed with unadult

10 In the first step, a small protein is designed that binds a sin

11 ur antigen specific mAb conjugates are, in a first step, administered into a patient.

12 are identified by database searching in the first step, all MS data are considered to select biomark

13 In the first step, an expert panel, using the modified RAND-UCL

14 In the first step, an intramolecular propargylic ene reaction g

15 methods, that consists in a "flat" learning first step and a hierarchical combination of the predict

16 by the formation of planar 3-radicals in the first step and the stabilization of 4'-radicals in the s

17 iCBT can be considered as an evidence-based first-step approach in treating symptoms of depression.

18 note, the TMEM106B allele identified in the first step as being associated with better residual cogn

19 In the first step, bromide end layer was electrochemically graf

20 predicted this initial dip, suggesting that first-step decision dynamics depend on additive integrat

21 as predicted by the HLCA and PEI models, the first-step decision dynamics were initially biased towar

22 nY2 -TMA complexes (Y = I(-) , F(-) ) in the first-step deposition, followed by intercalating with FA

23 The first step during colonization and infection is bacteria

24 The first step, finding out whether an identifier in the use

25 It is, therefore, a critical first step for any downstream co-localised cross-slide a

26 Plant litter decomposition is an important first step for carbon and nutrient turnover, and litter

27 g imaging of urine sediments was used in the first step for fast preselection of urothelial cells, wh

28 this a computationally demanding problem, a first step for this aim is to facilitate tractability of

29 ting agents likely represents an encouraging first step for this latter population, and it is hoped w

30 of RNA molecules from cells is typically the first step for transcriptomic analysis.

31 ormalize, and filter RNA-Seq data - critical first steps for any subsequent analysis.

32 gh diet, exercise, and smoking cessation are first steps for patients with a proinflammatory response

33 First steps have been reported with respect to proof-of-

34 The PR --> F transition is the first step in a catalytic cycle that requires proton tra

35 e computational model here only represents a first step in a new approach to understanding the comple

36 to a receptor(s) on a host cell acts as the first step in a series of events culminating in fusion w

37 erence-free particle picking is an important first step in a visual proteomics analysis of cell tomog

38 Adopting these Standards is the first step in achieving international standardization of

39 une infiltration of gliomas represents a key first step in achieving tumor destruction through immuno

40 As a first step in addressing these conditions, we study here

41 Here, we made a first step in addressing this issue by tracking the plas

42 Therefore, the very first step in analyzing the ensemble is an estimation of

43 Our analysis is a first step in bridging the gap between RMDs and empiric

44 This study provides a first step in characterizing distinct trafficking pathwa

45 thifying ecosystems and provide an important first step in characterizing the shared microbiome of mo

46 interactions, which promote C1q binding, the first step in classical pathway complement activation.

47 Reliable detection of CP-CRE is the first step in combating this problem.

48 As a first step in designing an effective HTLV-1 vaccine, we

49 hanges appear possible, suggesting this is a first step in developing a simple way of controlling pla

50 s to the extent of the problem as a critical first step in developing effective strategies for: (1) i

51 We believe that these results are a first step in developing methods to characterise large a

52 ibody half-life in vivo This is an important first step in developing safer therapeutics, and the nex

53 ctions, with nasal colonization an important first step in disease.

54 Diagnosis is a critical first step in effectively managing their spread.

55 mation of tubular ER in the mother cell, the first step in ER inheritance, depends on functional symm

56 midline fluid percussion injury (mFPI) as a first step in exploiting microglia morphology to reflect

57 This perspective is a first step in gathering information to allow provision o

58 The first step in glutamine catabolism is catalysis by the m

59 This morphological analysis provides the first step in identifying a potential role for biplexifo

60 As a first step in identifying genes associated with these tr

61 ide nanostructures may represent the crucial first step in integrating biology with nano-electronics

62 Read assignment is an important first step in many metagenomic analysis workflows, provi

63 The first step in methane metabolism is its oxidation to met

64 gnetic resonance imaging (MRI) is a critical first step in most neuroimage analysis pipelines.

65 Alignment is the first step in most RNA-seq analysis pipelines, and the a

66 Read alignment is the first step in most sequencing data analyses.

67 n of CB2R on activated microglial cells, the first step in neurodegeneration, has been widely demonst

68 Neurite initiation is the first step in neuronal development and occurs spontaneou

69 DNA end by the DNA repair protein Ku is the first step in NHEJ, followed by the iterative binding of

70 How the very first step in nucleosome assembly, deposition of histone

71 heating rate (2 degrees C/min) used for the first step in order to create a baseline for analysis.

72 with geographic structure, which is often a first step in phylogeographic analysis.

73 The first step in PM phosphoinositide synthesis is the conve

74 llular replication of S. pneumoniae as a key first step in pneumococcal pathogenesis within the heart

75 into the membrane and we propose this as the first step in pore formation, mediated by the nisin N-te

76 As a first step in potential standardization of EVs isolation

77 An urgent, critical first step in solving this problem is replacing the Jour

78 ubunit of ADP-glucose pyrophosphorylase, the first step in starch synthesis, and the suc2 mutation di

79 inhibits CD3 ITAM phosphorylation, a crucial first step in T cell activation.

80 on protospacer-adjacent motifs (PAMs) as the first step in target recognition.

81 yptophan to 7-chlorotryptophan, which is the first step in the antibiotic pyrrolnitrin biosynthesis.

82 (COase) is a bacterial enzyme catalyzing the first step in the biodegradation of cholesterol.

83 n into the endoplasmic reticulum (ER) is the first step in the biogenesis of thousands of eukaryotic

84 The first step in the biosynthesis of nearly all plant membr

85 This reaction is the first step in the biosynthesis of the quinaldic acid moi

86 Its reaction is the first step in the biosynthesis of the unique quinaldic a

87 Screening methods are the first step in the control of antibiotic residues in food

88 complementation experiments confirm that the first step in the conversion of PA-B into the major prod

89 ed with an alternative pathway, an essential first step in the creation of a designer organelle.Desig

90 landin dehydrogenase (15-PGDH) catalyzes the first step in the degradation of prostaglandins includin

91 chieve multifunctional surfaces represents a first step in the design of novel cell-instructive bioma

92 with compounds 11a and 12b representing the first step in the development of a novel class of drugs

93 This work represents a first step in the development of a real-time RSV predict

94 nstrate whether LAR should be considered the first step in the development of allergic rhinitis (AR)

95 ing blood to atherosclerotic foci is the key first step in the development of atherosclerosis.

96 Together, these data represent an important first step in the development of protein polymer conjuga

97 and other pathway components, providing the first step in the development of rational guidelines for

98 Our results provide new insights into the first step in the establishment of S. aureus colonizatio

99 Catecholamine-induced lipolysis, the first step in the generation of energy substrates by the

100 ust female social defeat model is a critical first step in the identification and development of nove

101 ex (ORC) to origins of replication marks the first step in the initiation of replication of the genom

102 The first step in the post-transcriptional regulatory functi

103 handle for activating/deactivating the very first step in the redox chain.

104 As a first step in the selection of mitigation strategies, th

105 The first step in the traditional process (maize grits cooki

106 We conclude that ZnO NPs prevent the first step in the translocation of cholera toxin into in

107 n of DNA double-strand breaks is the crucial first step in their repair via homologous recombination.

108 Acyl-CoA oxidases, which catalyze the first step in these beta-oxidation cycles, have differen

109 The first step in these pathways typically involves the bind

110 Here, we undertake a first step in this direction by focussing on the pressur

111 As a first step in this direction, we investigate here the pr

112 As a first step in this direction, we investigated data quali

113 plement of Clinical Infectious Diseases is a first step in this direction.

114 The first step in this pathway is catalyzed by a flavoprotei

115 The OM lipoprotein MlaA performs the first step in this process via an unknown mechanism that

116 As a first step in this process, we developed a standardized

117 dide (I(-)) accumulation in the thyroid, the first step in thyroid hormone (TH) biosynthesis.

118 As such, it represents an essential first step in translating animal data into the clinic.

119 p these conceptual confusions is a necessary first step in understanding how general intelligence evo

120 aracterize their free energy landscapes as a first step in understanding the initial stages of diseas

121 s ( 1 , p. 19), the father of taxonomy, "The first step in wisdom is to know the things themselves; t

122 19), the father of taxonomy, "The first step in wisdom is to know the things themselves; t

123 he U6 snRNP that are critical for one of the first steps in assembly of the megaDalton U4/U6.U5 tri-s

124 This study takes the first steps in evaluating these animals' communication s

125 Although these are only the first steps in implementation of proteomics into the cli

126 faces of such vesicles, thereby blocking the first steps in its aggregation process.

127 However, the first steps in the formation of hydroxyaluminosilicates

128 One of the first steps in this process involves displacement of the

129 rganized tissue microenvironment to take the first steps into becoming aggressive tumors.

130 These results represent first steps into the uncharted territory of therapy targ

131 ddress issues of scalability, describing our first steps into the use of text mining to identify prot

132 The first step involves a change in the distance between the

133 The first step involves a nucleophilic substitution reaction

134 factor 1 (HCF-1) by a mechanism in which the first step involves glycosylation on glutamate.

135 Experimental evidence had shown that the first step involves the generation of F atoms from F2 ,

136 onventional metabolic pathways, in which the first step is rate-limiting and metabolic intermediates

137 We show that an important first step is to ask whether the functional unit of path

138 The measured rates for the first step (k1 approximately 10(-4) M(-1) s(-1)) are 2-3

139 pproach, the gene clusters identified in the first step may have little overlap among different speci

140 The first step Mendelian randomization estimated that matern

141 geneity makes RNASeq on PBMC unsuitable as a first-step method for screening biomarker candidates in

142 The first step models the association between the genotype a

143 in PLOS Biology by Ono et al. finds that the first-step mutations selected in yeast populations evolv

144 In the first step (n = 979), we performed a genome-wide associa

145 ough mixing of the starting materials is the first step of a crystal growth procedure.

146 etohydroxyacid synthase (AHAS) catalyzes the first step of branched-chain amino acid (BCAA) biosynthe

147 nosylmethionine (SAM) enzyme involved in the first step of diphthamide biosynthesis.

148 ples were heated in acidic conditions at the first step of extraction (Protocol 1).

149 Chalcone synthase (CHS) catalyzes the first step of flavonoid biosynthesis by directing carbon

150 Pyruvate carboxylase, which catalyzes the first step of gluconeogenesis, was also downregulated by

151 Hexokinases (HKs), which catalyze the first step of glycolysis, have been identified to play a

152 coding for hexokinase-2, which catalyzes the first step of glycolysis, was significantly lower expres

153 ulinate synthase (ALAS), which catalyzes the first step of heme synthesis.

154 The first step of human biosonar is the transmission (mouth

155 o receptors on neuronal cell surfaces as the first step of invasion.

156 extracted by the LptB2FG complex during the first step of LPS transport to the outer membrane.

157 The adenylating enzyme MbtA catalyzes the first step of mycobactin biosynthesis in two half-reacti

158 (AOB) and archaea (AOA) are involved in the first step of nitrification and are important to ecosyst

159 At the first step of our method we test whether there exists an

160 In the first step of peptide generation, proteins are degraded

161 ar systems, it has been established that the first step of photoinduced electron transfer can be fast

162 notion that loss of ndh gene function is the first step of plastome degradation in the transition to

163 gnate tRNA molecules, which is the essential first step of protein translation.

164 osome (Bact), the spliceosome just after the first step of splicing (C), and the spliceosome activate

165 ause of the greater charge separation in the first step of the [2 + 2] cycloaddition.

166 11 human DNA glycosylases that catalyze the first step of the BER pathway, i.e. recognition and exci

167 und that FeNTf2 is an effective catalyst for first step of the domino isomerization, transformation o

168 neutralizes toxin activity by inhibiting the first step of the intoxication cascade.

169 Theoretical calculations show that the first step of the main mechanism is the photodissociatio

170 yl-CoA oxidase, which is responsible for the first step of the peroxisomal fatty acid (FA) beta-oxida

171 In stepwise mechanisms, the first step of the reaction is a rare case in which the n

172 The first step of the ring opening of the epoxide is the rat

173 The first step of the surgery was L2-S1 fusion with decompre

174 m in our study, particularly in the critical first step of timely linkage to care following diagnosis

175 the regions close to the active site in the first step of unfolding, i.e., the N-I1 transition.

176 e broad-spectrum substances that prevent the first step of virus-cell interaction by mimicking hepara

177 Our results thus provide the first steps of a comparative study between the gauge col

178 make use of this chemistry to coordinate the first steps of DNA synthesis.

179 more, we implement a parameterization of the first steps of growth in a global aerosol model and find

180 te inflammation only takes place after these first steps of immune modifications.

181 nd this research sheds new light on the very first steps of infection of this important pathogen.IMPO

182 nderstand the molecular requirements for the first steps of locus activation, we investigated whether

183 ort events that enable proton pumping during first steps of oxidation of the fully reduced enzyme.

184 During the first steps of photosynthesis, the energy of impinging s

185 ional chains provide a glimpse into the very first steps of the transformation from white to red phos

186 to recapitulate this trajectory, one of the first steps of which was a change in leaf anatomy.

187 orage compared to the others obtained in the first steps of whitening.

188 ces in natural scenes, performing a critical first step on which other face processing operations can

189 In a first step, participants choose between two potential up

190 Second, based on results from the first step, Poisson regression analysis was used to deri

191 In a first step, reproduction of patient anatomy was tested b

192 In first step, sequence homology-based genetic analysis of

193 In the first step, small concentrations of Se and S were substi

194 This work lays first step stone towards real-time electrochemical quant

195 s problem for static networks, but this is a first step study to explore designing surveillance syste

196 In a first step, the elongation modes of recombinant capsular

197 nts compared with other treatment options as first-step therapies for acute MDD.

198 ressed by researchers and it marks a crucial first step to analyzing the structural health of the mat

199 of this problem in the field is an important first step to developing coordinated, strategic approach

200 Therefore, these studies are only the first step to discern whether natural selection is respo

201 ng at the atomic level, it is necessary in a first step to drastically reduce complexity and then sys

202 As a first step to elucidating the global 3D organization (to

203 edure that we describe provides an important first step to epigenetic quantitative trait loci mapping

204 Though this safety study was an important first step to evaluate e-POCT, its true utility should b

205 erification of its existence is an important first step to exploring the consequences of the J eff =

206 These results are a first step to gain a better understanding of how mood fl

207 ded (ds) DNA breaks at a target locus as the first step to gene correction.

208 Furthermore, as a first step to identifying PTPRG.CNTN complexes in vivo,

209 Plant pathogen detection is important as first step to manage a plant disease in greenhouses, fie

210 Clustering is often the first step to perform in sequence analysis, and hierarch

211 g where patients access health services is a first step to planning for the placement of services to

212 The first step to reducing nitrogen load and improving water

213 As a first step to test this possibility, we used pharmacolog

214 This study represents the first step to the ultimate goal of developing a cost-eff

215 ons in known monogenic diabetes genes is the first step to then allow us to concentrate on remaining

216 omere dynamics in vivo, which is a necessary first step to understand movement disorders and to creat

217 and other temporal factors that constitute a first step to understanding how and why music literally

218 Five first steps to creating a program are: dedicate a coordi

219 rgeted imaging agents, it is important, as a first step, to understand how the signal is affected by

220 tral goal in neuroscience and is a necessary first step toward a circuit-level understanding of how t

221 The results here show the first step toward a manufacturing infrastructure for tra

222 As a first step toward a molecular understanding of how Toc15

223 As a first step toward addressing this issue, we developed a

224 This paper proposes a first step toward an alternative computational framework

225 nfluence mitochondrial dynamics and aging, a first step toward analogous manipulations to modulate hu

226 This study represents a first step toward assessing the development of functiona

227 Our findings constitute a first step toward capturing pluripotent stem cells with

228 misorbed CO2 in the presence of water as the first step toward CO2 reduction products such as formate

229 A key first step toward elucidating the mechanism by which S-n

230 Identification of the linkage is a first step toward identifying the linking enzyme and pot

231 As a first step toward identifying the machinery mediating th

232 This study is the first step toward implementing in situ carbon sequestrat

233 ability to bacteria in marine systems is the first step toward its bioamplification in food webs.

234 ization of the new peptide psiRGDechi as the first step toward novel-targeted theranostics in melanom

235 saminyltransferase 1 (POMGNT1) catalyzes the first step toward other various glycan structures presen

236 KEY POINTS: This study represents a first step toward predicting mechanisms of sex-based arr

237 utational approach presented here could be a first step toward predicting rejections trends of, for e

238 This study represents a first step toward predicting therapeutic mechanisms of d

239 LAIV may be a first step toward the desired universal influenza vaccin

240 This knowledge is a first step toward the development of novel therapeutics

241 We present the first step toward the development of such technology.

242 saminyltransferase 2 (POMGNT2) catalyzes the first step toward the functional matriglycan structure o

243 As a first step toward the realization of such machines, whic

244 dentifying genomic variants is a fundamental first step toward the understanding of the role of inher

245 ation of resilient individuals may provide a first step toward uncovering protective genetic variants

246 A first step toward understanding cochlear neurodegenerati

247 structure (EXAFS) spectroscopy constitutes a first step toward understanding how impurities and conta

248 The result is an important first step toward understanding the biological functions

249 This work is a first step toward understanding the requirements for vis

250 Here we take the first steps toward a rapid cost-effective surface plasmo

251 These data are important first steps toward implementation of precision head and

252 The first steps toward maize (Zea mays subspecies mays) dome

253 Current experiments are taking the first steps toward noise-resilient logical qubits.

254 Here we show the first steps toward not only the detection of glycosylati

255 Although the first steps toward potential therapies have been taken,

256 mmarizes recent studies that illustrate some first steps toward successfully answering these modern b

257 This represents the first steps toward the development of a single RDT-based

258 This approach may represent the first steps toward the development of a technology to in

259 d fossil [4-7] data indicate that one of the first steps toward the shelled body plan was broadening

260 nt loci for cannabis dependence is among the first steps toward understanding the biological contribu

261 As a first step towards a comprehensive study of descending m

262 This study serves as a first step towards a computer-aided detection/diagnosis

263 This constitutes a first step towards a fully integrated system for rapid l

264 good to excellent yield, and represents the first step towards a general transition metal catalysed

265 It is a first step towards a mathematical characterization of th

266 This work represents the first step towards a quantum network for high-dimensiona

267 S, these positive results could indicate the first step towards abolition of complete locked-in state

268 --to environmental variability, which is the first step towards addressing why some regions appear to

269 r, these closed-form solutions represent the first step towards an analytical framework for wavetrain

270 The results show that this strategy is a first step towards developing "activator drugs" for a la

271 lectrodes fabricated on glass-substrate as a first step towards developing a miniaturized platform.

272 Our demonstration represents an important first step towards developing practical and monolithic I

273 As a first step towards dissecting these circuits, we optogen

274 on of a non-RNA-guided Cas9 endonuclease and first step towards eliminating the ribose dependency of

275 Here, we present a first step towards empirically investigating the probabi

276 angling species relationships, and provide a first step towards future genomic studies in Trithuria.

277 Our results constitute a first step towards implementing p-bits with nano devices

278 r glucosinolate and polyphenol contents as a first step towards industrial bio-refining.

279 ional regions from non-coding regions is the first step towards lincRNA recognition.

280 This experiment constitutes a first step towards measurements of ultrafast atomic dyna

281 proach for the diagnosis of cHP represents a first step towards the development of international guid

282 d was liable to cell repopulation, a crucial first step towards the generation of urethra bioscaffold

283 These genomic resources are an important first step towards the genetic improvement of quinoa.

284 The first step towards the molecular characterisation of PPI

285 rties of charge in a transport experiment, a first step towards their potential application.

286 candidate genes for phenocopy as a critical first step towards understanding disease mechanisms of t

287 ard, we believe that this model represents a first step towards understanding reconciliations in dupl

288 In general, our results represent the first step towards understanding the effect of structura

289 These results provide an important first step towards understanding the nature of variabili

290 published, Canver et al. have now taken the first steps towards addressing these issues by increasin

291 Our framework provides first steps towards light-based non-von Neumann arithmet

292 To take first steps towards such a multifunctional surface we pr

293 lification-based assays, these results are a first-step towards application of this technology to the

294 As a first step we have investigated the possibility of repla

295 In a first step, we modeled historical and future change in t

296 As a first step, we present models for various cell organelle

297 lve the reconstruction problem, where in the first step, we recover both direct and indirect interact

298 As a first step, we show that, in operando, MAPbI3 (unlike MA

299 ion implied by the rate differences at these first steps, we compared the kinetics of KIF3AB microtub

300 specific recombination reactions is that the first step, XerD-mediated strand exchange, relies on int