ライフサイエンスコーパス: first trimester

1 escriptions filled both during and after the first trimester).

2 uorononanoic acid (PFNA) in maternal plasma (first trimester).

3 es (34-191) per 10,000 women infected in the first trimester.

4 t 1 prescription for a typical AP during the first trimester.

5 n began the use of antenatal care during the first trimester.

6 s whose mothers reported symptoms during the first trimester.

7 antenatal systemic therapy and 2 during the first trimester.

8 d ratio, 1.26; 95% CI, 0.91-1.74) or for the first trimester.

9 omen were exposed to omalizumab during their first trimester.

10 Six miscarriages (8%) occurred during the first trimester.

11 with arteries only appear at the end of the first trimester.

12 4 mRNA levels in the third trimester but not first trimester.

13 o ICS monotherapy at higher doses during the first trimester.

14 ssociated with deficient placentation in the first trimester.

15 ttributable to antidepressant use during the first trimester.

16 reported at least 1 instance of a GUI in the first trimester.

17 easurement of fetal crown-rump length in the first trimester.

18 women (6.8%) used antidepressants during the first trimester.

19 y consistent with infection occurring in the first trimester.

20 y that occur in pregnancy, especially in the first trimester.

21 ission in women with positive CMV IgM in the first trimester.

22 a 1- month interval after completion of the first trimester.

23 tor or triple-nucleoside regimens during the first trimester.

24 the occurrence of FD was related only to the first trimester.

25 nancies and often became detectable from the first trimester.

26 r, but nonsignificant, point estimate in the first trimester.

27 and ambient temperature exposures during the first trimester.

28 increased pregnancy termination rate in the first trimester.

29 359 Chinese women with ALT measured in their first trimester.

30 sure to traffic-related pollution during the first trimester (0.0538 ppm carbon monoxide, estimated u

31 Three patients were scanned during the first trimester (1 with PET and 2 with PET/CT), 2 were s

32 the vaccine, 14 385 were exposed within the first trimester (14 weeks), and 7502 were exposed during

33 gns and symptoms during pregnancy, 18 in the first trimester, 4 in the second trimester, and 1 in the

34 rse outcomes after maternal infection in the first trimester, 52% after infection in the second trime

35 8,486 women exposed to metoclopramide in the first trimester, 721 had an infant with a major congenit

36 duced placental growth factorproduction from first-trimester (8-12 weeks gestation) human placental e

37 s (58.3%) were born to women infected in the first trimester, 8 (33.3%) in the second trimester, and

38 y pregnancy, 1.3E-02 in the late part of the first trimester, 8.5E-03 in the second trimester, and 5.

39 een the three groups (lithium-exposed in the first trimester: 8/123 [6.5%]; bipolar: 2/61 [3.3%]; non

40 hers who used protease inhibitors during the first trimester (adjusted odds ratios, 1.55 and 1.59, re

41 -0.23% to 0.56%) for vaccination during the first trimester and 0.10% (CI, -0.41% to 0.62%) for vacc

42 1]pdm09 vaccine during pregnancy [345 in the first trimester and 6644 in the second or third trimeste

43 Associations were most pronounced in the first trimester and among Hispanic women.

44 or treatment of uncomplicated malaria in the first trimester and artemisinin-based combination therap

45 use) in the prepregnancy period through the first trimester and asthma in childhood (summary risk es

46 design, pregnant women were enrolled in the first trimester and began receiving their allocated supp

47 concentrations greater than 2.5 mIU/L in the first trimester and greater than 3 mIU/L in the second a

48 e majority of these vaccinations were in the first trimester and in 83 (62%), no AE was reported.

49 on deficiency, recommending oral iron in the first trimester and IV iron later.

50 osure exclusively in the first trimester (or first trimester and periconceptional period), with no re

51 of pregnancies infected with ZIKV during the first trimester and provide estimates of microcephaly ca

52 ceptors localized to cytotrophoblasts in the first trimester and to syncytiotrophoblasts in the third

53 ers demonstrated a viral syndrome during the first trimester and who subsequently were born with micr

54 MT1-MMP protein was localized in first-trimester and term placentas.

55 ation Service were followed up (90.2% in the first trimester) and compared with 72 disease-matched an

56 a healthy infant, 2 had miscarriages in the first trimester, and 1 had fetal death, with the macerat

57 ccinated, 349 mothers were vaccinated in the first trimester, and 5962 mothers were vaccinated in the

58 tients, the valve thrombosis occurred in the first trimester, and all 5 patients had been switched to

59 etermined by a dating ultrasound scan in the first trimester, and infant birth anthropometric measure

60 ess, to develop safe drugs to be used in the first trimester, and to consider preconceptional interve

61 on, the increase in the sex ratio during the first trimester, and total mortality during pregnancy be

62 tion filled), "first trimester only," "after first trimester," and "both" (prescriptions filled both

63 PD status in an independent N=51 women using first trimester antenatal gene expression levels of HP1B

64 orted first-trimester antidepressant use and first-trimester antidepressant dispensations.

65 ernative hypotheses for associations between first-trimester antidepressant exposure and birth and ne

66 or pregnancy, maternal, and paternal traits, first-trimester antidepressant exposure was associated w

67 Maternal self-reported first-trimester antidepressant use and first-trimester a

68 bination therapies, it is time to reconsider first-trimester antimalarial treatment recommendations.

69 f major congenital anomalies was similar for first-trimester artemisinin (1.5% [95% CI 0.6%-3.5%]) an

70 used to evaluate the association of CAs with first-trimester ARV exposures, adjusting for demographic

71 among infants exposed to lithium during the first trimester as compared with unexposed infants and,

72 mbination chemotherapy administered past the first trimester, as early as 13 weeks gestation, was ass

73 cy from a failed or ectopic pregnancy in the first trimester; assigning gestational age and assessing

74 eton pregnancies were recruited during their first trimester at two major Singapore maternity hospita

75 With first-trimester atazanavir exposure, risks were highest

76 Preterm birth risk tended to increase with first-trimester average atmospheric pressure (odds ratio

77 ce of an increase in preterm birth risk with first-trimester average temperature in the -5 degrees C

78 Chemotherapy is contraindicated during the first trimester because of a higher risk of fetal malfor

79 ight be most vulnerable to ZIKV early in the first trimester before a protective zone of mature villo

80 After adjustment for first trimester body mass index and mean arterial pressu

81 Higher first-trimester BPA exposure was associated with signifi

82 laparoscopic biopsy was performed during the first trimester, but complete removal of the mass was de

83 s received an influenza vaccination in their first trimester, but the association was not statistical

84 tal region), and binge-level exposure in the first trimester (chin).

85 DNA methylation in first-trimester chorionic villi was assessed in chromoso

86 d late-gestation placentas and explants from first-trimester chorionic villi with the prototype Ugand

87 Vitamin K antagonist use in the first trimester compared with heparin was associated wit

88 infants (5.5%) exposed to the vaccine in the first trimester, compared with 15 of 330 unexposed infan

89 d in 31 of 330 infants (9.4%) exposed in the first trimester, compared with 24 of 330 unexposed infan

90 ificantly increased levels of LBP during the first trimester, compared with HIV-infected women with d

91 We sought to determine whether higher first-trimester concentrations of alpha-tocopherol and g

92 Weight-averaged aggregate first-trimester DBP exposures were assigned to individua

93 Immunostaining of first trimester decidua localized IP-10, I-TAC, IFN-gamm

94 The maternal leukocytes of the first-trimester decidua play a fundamental role in impla

95 In human first-trimester decidual cells incubated with estradiol,

96 availability of both a urine sample from the first trimester (defined as </=13 weeks' gestation; medi

97 These results suggest that first-trimester DES exposure may be associated with an i

98 Maternal first-trimester dietary factors are associated with chil

99 We assessed the association of maternal first-trimester dietary intake during pregnancy with chi

100 ensations before pregnancy and with paternal first-trimester dispensations were consistent with findi

101 and similar but weaker effect estimates for first trimester drinking.

102 ernal blood samples were obtained during the first trimester, during the third trimester, and at deli

103 First-trimester energy-adjusted maternal protein intake

104 In conclusion, elevated ALT levels in the first trimester even within normal range predicted GDM r

105 ing recommended for malaria treatment in the first trimester except in lifesaving circumstances.

106 LPS exposure in first-trimester explants decreased (P < 0.001) ABCB1 and

107 as observed in 25 of 330 infants (7.6%) with first-trimester exposure compared with 31 of 330 unexpos

108 n, after accounting for confounding factors, first-trimester exposure to antidepressants, compared wi

109 First-trimester exposure to any ARV and to specific ARV

110 The study confirmed increased odds of first-trimester exposure to inhaled beta2-agonists for c

111 Of 214 live births with first-trimester exposure to second-generation antipsycho

112 At the population level, first-trimester exposure was associated with all outcome

113 es of adverse fetal outcomes associated with first-trimester exposure.

114 In adjusted models, no association of first-trimester exposures with CAs was found for any ARV

115 A up-regulated in preeclamptic placentas, in first-trimester extravillous trophoblasts.

116 (forehead), moderate to high exposure in the first trimester (eyes, midface, chin, and parietal regio

117 First-trimester falciparum and vivax malaria both increa

118 arriage increased 1.61-fold after an initial first-trimester falciparum episode (95% CI 1.32-1.97; p<

119 ebral organoids to recapitulate early stage, first trimester fetal brain development.

120 he origin of the disease can be found in the first trimester fetal placenta.

121 (LMWH) throughout pregnancy; 3) LMWH for the first trimester, followed by a VKA (LMWH and VKA); or 4)

122 d VKA); or 4) unfractionated heparin for the first trimester, followed by a VKA (UFH and VKA).

123 exposure and groups with low exposure in the first trimester (forehead), moderate to high exposure in

124 ocular findings reported symptoms during the first trimester (frequency, 0.48; 95% CI, 0.02-0.67; P =

125 fetuses, either diagnosed with a CHD in the first trimester (Group I, 127 fetuses) or only in the se

126 First trimester human decidua is composed of decidual ce

127 s evaluated by whole-genome expression in 67 first trimester human embryonic and fetal ovaries and te

128 e characterize the first emerging B cells in first-trimester human embryos, identifying a development

129 diffuse expression of KDR and PDGFRalpha in first-trimester human fetal hearts.

130 Using first-trimester human placental explants, we demonstrate

131 narrow 'early window' of sensitivity within first trimester, ibuprofen causes direct endocrine distu

132 Drug therapy should be avoided during the first trimester if possible and drugs with the longest r

133 ure, a recurrent case of POC detected in the first trimester in a mother whose previous pregnancy als

134 A testing with standard screening during the first trimester in routine prenatal populations.

135 ally with a series of echocardiograms in the first trimester, in the third trimester, and postpartum.

136 In trimester-specific analyses, first-trimester influenza vaccination was the only perio

137 Results for first-trimester intake were in the same direction but we

138 Results were similar for first-trimester intake.

139 Excessive GWG in the first trimester is a risk factor for asthma exacerbation

140 The first trimester is the time window of interest for malfo

141 We aimed to assess the effect of first-trimester malaria and artemisinin treatment on mis

142 d 2013, 25 485 pregnancies were analysed for first-trimester malaria and miscarriage, in which 2558 (

143 ria and miscarriage, in which 2558 (10%) had first-trimester malaria.

144 ing the Integrated test (or 1.5 to 1.4% with first trimester markers measured at 11 weeks).

145 At a 90% DR with first trimester markers measured at 13 weeks, adding PlG

146 We examined associations between first-trimester maternal plasma PFAS concentrations and

147 First-trimester maternal protein intake was not signific

148 Higher first-trimester maternal protein, calcium, and phosphoru

149 First-trimester maternal total protein intake was associ

150 hroughout pregnancy, although use during the first trimester may increase the risk of cleft palate fo

151 Maternal vitamin E status in the first trimester may influence risk of early pregnancy lo

152 First trimester median PlGF was 15%, 28% and 39% lower i

153 egnant rhesus monkeys to induce MIA: 1) late first trimester MIA (n = 6), and 2) late second trimeste

154 When evaluated with unfamiliar conspecifics, first trimester MIA offspring deviated from species-typi

155 l processing capabilities in a subset of the first trimester MIA-exposed offspring (n = 4) and contro

156 variation in HBD2 protein expression in the first trimester might be useful to predict risk of prete

157 tment does not adversely affect fertility or first trimester miscarriage, although it is associated w

158 The adjusted hazard of first-trimester miscarriage was lower with higher 25(OH)

159 We found an association between 25(OH)D and first-trimester miscarriages, suggesting vitamin D as a

160 During 1 month preconception through the first trimester, mothers of limb deficiency, cleft palat

161 Comparing first-trimester MRI (n = 1737) to no MRI (n = 1418451),

162 For first-trimester MRI exposure, the risk of stillbirth or

163 In the first trimester (n = 2), the sensors were inserted only

164 h the use of artemisinins anytime during the first trimester (n = 37/671) compared with quinine (n =

165 Invariably, acute leukemia diagnosed in the first trimester necessitates intensive chemotherapy that

166 to the following 4 groups in relation to the first trimester: "none" (no prescription filled), "first

167 Although first-trimester O3 exposure was not associated with CIMT

168 k of placental growth and development in the first trimester occurs under low oxygen tension.

169 ated with acute lymphoblastic leukemia [ALL; first trimester odds ratio (OR) = 1.05; 95% CI: 1.01, 1.

170 n mean nitrogen dioxide concentration in the first trimester (odds ratio (OR) = 1.16, 95% confidence

171 captopurine, or corticosteroids during their first trimester of fetal development.

172 mothers who had a viral syndrome during the first trimester of gestation in an area that subsequentl

173 ring pregnancy does not adequately cover the first trimester of gestation in high-transmission areas.

174 riods of early development, ranging from the first trimester of gestation to age 6-12 mo.

175 During the first trimester of gestation, oxygen tension rises steep

176 al: 1.09, 1.97) after famine exposure in the first trimester of gestation.

177 de spectrum of presentation on ultrasound in first trimester of gestation.

178 (at a time point analogous to the end of the first trimester of human gestation) in ways relevant to

179 larger gestational weight gain (GWG) in the first trimester of pregnancy (P < .001) and increased to

180 increasing severe abdominal pain during the first trimester of pregnancy and increasing abdominal di

181 enrollment and micronutrient use during the first trimester of pregnancy appeared to be of particula

182 Low 25(OH)D serum concentrations in the first trimester of pregnancy are not associated with adv

183 ecommended for falciparum malaria during the first trimester of pregnancy because of safety concerns.

184 artery Doppler resistance index (RI) in the first trimester of pregnancy can be used as a proxy meas

185 Exposure to MRI during the first trimester of pregnancy compared with nonexposure w

186 Progesterone therapy in the first trimester of pregnancy did not result in a signifi

187 ber 30, 2014, among mothers recruited in the first trimester of pregnancy from low-risk, public mater

188 t animal, maternal protein intake during the first trimester of pregnancy is associated with a higher

189 alovirus (CMV) immunoglobulin M (IgM) in the first trimester of pregnancy is ill-defined.

190 ystemic therapy given for lymphoma after the first trimester of pregnancy is likely safe and results

191 magnetic resonance imaging (MRI) during the first trimester of pregnancy or with gadolinium enhancem

192 Use of inhaled corticosteroids during the first trimester of pregnancy seems to be safe in relatio

193 n, acute parvovirus B19 infection during the first trimester of pregnancy was associated with an incr

194 cohort of pregnant women (n = 670) in their first trimester of pregnancy was enrolled and followed u

195 , use of intranasal triamcinolone during the first trimester of pregnancy was not significantly assoc

196 febrile illness with rash at the end of the first trimester of pregnancy while she was living in Bra

197 whether progesterone supplementation in the first trimester of pregnancy would increase the rate of

198 esterified (free) fatty acids (NEFAs) in the first trimester of pregnancy would mark women at excess

199 sit, completed at least one visit during the first trimester of pregnancy, attended four or more appo

200 Magnetic resonance imaging exposure in the first trimester of pregnancy, or gadolinium MRI exposure

201 P. falciparum is already established in the first trimester of pregnancy, with consequent implicatio

202 t of serum samples were collected during the first trimester of pregnancy.

203 as best explained by a period of risk in the first trimester of pregnancy.

204 of mothers with a viral syndrome during the first trimester of pregnancy.

205 ter exposure to antiasthma medication in the first trimester of pregnancy.

206 from continued FA supplementation after the first trimester of pregnancy.

207 ernal daily cigarette consumption during the first trimester of pregnancy.

208 copy number and serum HBD2 expression in the first trimester of pregnancy; this might be due to varia

209 "none" group, infants born to women in the "first trimester only" group had higher relative odds of

210 trimester: "none" (no prescription filled), "first trimester only," "after first trimester," and "bot

211 st invasion into maternal decidua during the first trimester, optimizing hemochorial placentation.

212 high, or binge-level alcohol exposure in the first trimester or throughout pregnancy.

213 ess of whether exposure occurred only in the first trimester or throughout pregnancy.

214 255.8), and maternal trimester of infection (first trimester OR, 5.1; 95% CI, 1.9-13.2; second trimes

215 conception (OR = 1.52; 95% CI: 1.22, 1.89), first trimester (OR = 1.93; 95% CI: 1.55, 2.40), second

216 rnal symptoms or exposure exclusively in the first trimester (or first trimester and periconceptional

217 atever the trimester of exposure considered (first trimester: OR, 2.09, 95% CI,1.66-2.64; second: OR,

218 of liveborn infants in Denmark, we evaluated first-trimester oral fluconazole exposure and the risk o

219 We categorized first-trimester passive and active smoke exposure.

220 a set, we found a modest association between first-trimester passive smoking and oral clefts that was

221 the deleterious effect of an increased mean first-trimester phenylalanine concentration on FD.

222 Using human first trimester placenta, decidua, primary dNK cells, an

223 trophoblast and trophoblast debris shed from first-trimester placenta.

224 n of miR-377 and let-7a, but not miR-145, in first trimester placental explants significantly reduced

225 Incubation of first-trimester placental explants with TNF-alpha provok

226 e also seen in chorionic villi of one of the first trimester placentas.

227 First trimester PlGF measurements improve the performanc

228 oglobin in blood plasma can, as early as the first trimester, potentially serve as a diagnostic bioma

229 refore, also for embryonic growth during the first-trimester pregestational diabetic pregnancies when

230 congenital anomaly (primary outcomes) among first-trimester pregnancies treated with artemisinin der

231 We provide evidence that even in the first trimester, pregnancies with high uterine artery Do

232 nce of bacteria in the vaginal microbiome in first trimester pregnant women, 52 with their first know

233 or urine volume) in stored samples from 1040 first-trimester pregnant women.

234 er restricting the analysis to subjects with first-trimester prenatal care, a nonmissing date of the

235 mechanisms of deficient placentation in the first trimester remain poorly understood, although apopt

236 key model, exposure to MIA at the end of the first trimester results in abnormal gaze patterns to sal

237 rough all routes of BTHM exposure during the first trimester (RR for 1 mug/week=3.14; 95% CI: 1.16, 8

238 In a third group of first-trimester samples all progesterone sulfates were s

239 First trimester sCD14 and LBP levels and third trimester

240 independent association was observed between first trimester sCD14 levels and preterm delivery among

241 specificity than maternal serum screening or first trimester screening.

242 First-trimester screening had a significant impact on th

243 ith singleton pregnancies who were attending first-trimester screening in New South Wales, Australia.

244 The study analyzed the impact of first-trimester screening on the spectrum of congenital

245 n the second-trimester groups differed after first-trimester screening was implemented.

246 imester from 1996 to 2001, the period before first-trimester screening was introduced).

247 (2.33-microg/m(3)) increase in PM2.5 in the first trimester, second trimester, third trimester, and

248 48.6% female; 1.4% [n = 22544] with maternal first-trimester self-reported antidepressant use) born t

249 Significantly elevated IP-10 levels in first trimester sera from women eventually developing pr

250 iously shown that these women have increased first trimester serum HBD2.

251 ression models to estimate associations with first-trimester serum levels of triglycerides, total cho

252 First-trimester serum samples were tested for parvovirus

253 th genes and were higher at term than in the first trimester, so they were selected for further analy

254 Stillbirth was not associated with first-trimester SSRI use (adjusted odds ratio=0.77, 95%

255 For an average-sized pregnant patient at the first trimester, the 256-slice CTPA exposure resulted in

256 54% of pregnancies that progressed past the first trimester, the dose or the frequency of use of ecu

257 Use of APs during the first trimester, the etiologically relevant period for o

258 This was tested using a first trimester trophoblast-derived cell line (ACH-3P).

259 cts on ROS formation, resulting in decreased first-trimester trophoblast growth.

260 levels (21%) reduces proliferation of human first-trimester trophoblasts in a ROS-independent manner

261 A profiling of sorted populations of primary first-trimester trophoblasts, we evaluated the first sta

262 f around 12 weeks was referred for a routine first trimester ultrasound scan.

263 Each 1-percentage-point increase in the first-trimester unemployment rate was associated with a

264 During the Great Recession, however, first-trimester unemployment was associated with a 16% i

265 men received CSB Plus (treatment) during the first trimester until delivery or continued their normal

266 We analyzed associations between first-trimester urine concentrations of 8 phenols and 11

267 BPA was assayed in first-trimester urine samples from 385 participants who

268 natal mortality was not associated with SSRI first-trimester use (odds ratio=0.56, 95% CI=0.25-1.24),

269 significantly increased odds of exposure to first-trimester use of inhaled beta2-agonists compared w

270 ating evidence supports associations between first-trimester use of specific oral and possibly intran

271 th adjustment for maternal age, smoking, and first-trimester vaginal bleeding, standard guidelines fo

272 intake (each additional z score) during the first trimester was associated with 47% reduced odds of

273 Maternal use of lithium during the first trimester was associated with an increased risk of

274 Finally, gestational infection during the first trimester was associated with lower cord-blood tot

275 l exposure to multiple air pollutants in the first trimester was associated with lower DNA methylatio

276 Higher milk intake during the first trimester was associated with reduced asthma (OR,

277 red to quinine, artemisinin treatment in the first trimester was not associated with an increased ris

278 2 888 children included, ZDV exposure in the first trimester was significantly associated with CHD (1

279 Maternal weight gain from 0 to 13 wk (first trimester) was not associated with fetal size at 1

280 More than 5 kg first-trimester weight gain was associated with an incre

281 t low vitamin B-12 and folate intakes in the first trimester were independently associated with a hig

282 Children exposed in the first trimester were not more likely to be hospitalized

283 her trimesters, but models that excluded the first trimester were not supported by the data.

284 ydrocarbons before conception and during the first trimester were significantly associated with 8%-20

285 oid-exposed, and nonexposed women during the first trimester were studied for major congenital malfor

286 microcephaly given maternal infection in the first trimester were the primary drivers of both magnitu

287 es and reported taking FA supplements in the first trimester, were randomly assigned at the start of

288 ntly in the lithium group exposed during the first trimester when compared with the nonteratogenic ex

289 miR species whose expression differs between first trimester, when cytotrophoblast proliferation is r

290 as strongest for women exposed to DES in the first trimester, when exposure corresponds to early stag

291 diffuses to the fetal circulation during the first trimester, when organogenesis occurs.

292 Around the end of the first trimester, when the placenta becomes susceptible t

293 ic pregnant women exposed to ICSs during the first trimester who delivered between January 1990 and M

294 y were measured in 380 pregnant women in the first trimester who were recruited at the University Hos

295 ymptoms in pregnant women increased from the first trimester with 26.1 to 36.1% in the second trimest

296 ergy-adjusted SCB intake was assessed in the first trimester with a food-frequency questionnaire.

297 presented to antenatal clinics during their first trimester with a viable fetus.

298 ronger association beginning as early as the first trimester with post-delivery maternal serum leptin

299 to women who took antidepressants during the first trimester with the risk among infants born to wome

300 s and microcephaly, whereas among women with first-trimester Zika infection, 11% of fetuses or infant